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MCL coexpression mm9:469

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Phase1 CAGE Peaks

 Short description
Mm9::chr18:65382340..65382345,-p@chr18:65382340..65382345
-
Mm9::chr2:5597108..5597111,-p11@Camk1d
Mm9::chr3:121517222..121517245,-p@chr3:121517222..121517245
-
Mm9::chr3:138037110..138037127,+p1@Adh6-ps1
Mm9::chr4:41691973..41691986,-p9@Sigmar1
Mm9::chr6:121087499..121087514,+p@chr6:121087499..121087514
+
Mm9::chr7:15021789..15021806,-p@chr7:15021789..15021806
-
Mm9::chr7:20283537..20283548,-p@chr7:20283537..20283548
-
Mm9::chr8:129971569..129971578,+p16@Pard3
Mm9::chr8:88125923..88125936,+p@chr8:88125923..88125936
+
Mm9::chr8:88125941..88125950,+p@chr8:88125941..88125950
+
Mm9::chr8:88125965..88125972,+p@chr8:88125965..88125972
+
Mm9::chr8:89139298..89139300,+p@chr8:89139298..89139300
+
Mm9::chr9:42070219..42070224,-p@chr9:42070219..42070224
-
Mm9::chr9:42072287..42072302,-p2@Sc5d
Mm9::chr9:62193253..62193260,+p@chr9:62193253..62193260
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0016125sterol metabolic process0.0124910973538596
GO:0050046lathosterol oxidase activity0.0124910973538596
GO:0046996oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NADH or NADPH as one donor, and the other dehydrogenated0.0124910973538596
GO:0008202steroid metabolic process0.014831918205804
GO:0006707cholesterol catabolic process0.0214080307195393
GO:0016127sterol catabolic process0.0214080307195393
GO:0033344cholesterol efflux0.0214080307195393
GO:0006066alcohol metabolic process0.0218486435308822
GO:0006706steroid catabolic process0.0218486435308822
GO:0042627chylomicron0.0218486435308822
GO:0017127cholesterol transporter activity0.0218486435308822
GO:0015248sterol transporter activity0.0218486435308822
GO:0008034lipoprotein binding0.0318104378325636
GO:0042311vasodilation0.0318104378325636
GO:0030301cholesterol transport0.0318104378325636
GO:0004683calmodulin-dependent protein kinase activity0.0318104378325636
GO:0015918sterol transport0.0318104378325636
GO:0042632cholesterol homeostasis0.0318104378325636
GO:0055088lipid homeostasis0.0318104378325636
GO:0055092sterol homeostasis0.0318104378325636
GO:0044255cellular lipid metabolic process0.0361080724977768
GO:0007163establishment and/or maintenance of cell polarity0.0408027456076468
GO:0005913cell-cell adherens junction0.0415734311569283
GO:0006629lipid metabolic process0.0415734311569283
GO:0044242cellular lipid catabolic process0.0417010481539018
GO:0016126sterol biosynthetic process0.0417010481539018
GO:0003018vascular process in circulatory system0.0438151927516389
GO:0035150regulation of tube size0.0438151927516389
GO:0050880regulation of blood vessel size0.0438151927516389
GO:0005819spindle0.0473220262945199



Relative expression of the co-expression cluster over median <br>Analyst:



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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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