CL:0000092
From FANTOM5_SSTAR
Name: | osteoclast | ||
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Namespace: | FANTOM | ||
Definition: | "A specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes. This cell has the following markers: tartrate-resistant acid phosphatase type 5-positive, PU.1-positive, c-fos-positive, nuclear factor NF-kappa-B p100 subunit-positive, tumor necrosis factor receptor superfamily member 11A-positive and macrophage colony-stimulating factor 1 receptor-positive." [GO_REF:0000031, GOC:add, GOC:tfm, ISBN:0781735149, PMID:10428500, PMID:15055519, PMID:17380158] | ||
Xrefs: |
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Synonyms: | "chondroclast" RELATED [] | ||
Comments: | Morphology: Highly vesicular; markers: Surface: RANK, cFMS (MCSF receptor); Secreted: cathepsin K and TRAP (tartate resistant acid phosphatase); transcription factors: PU.1, cFOS, MITF, NFkB (p52); role or process: tissue remodelling: bone resorption; lineage: hematopoietic, myeloid. |
Ontology association
Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.
link to ontology dataset
data
Parents
is_a: | CL:0000766(myeloid leukocyte),CL:0001035(bone cell) |
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develops_from: | CL:0000576(monocyte) |
part_of: | UBERON:0001474(bone element) |
Children
derives from: | FF:0100969 (osteoclastoma cell sample),FF:0200020 (osteoclast, bone marrow-derived sample) |
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Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples
It includes FANTOM5 samples that overlay the Cell ontology.
Human (Homo sapiens)
- 10704-109H2 (osteoclastoma cell line:Hs 706.T)
- 10711-109H9 (fibrous histiocytoma cell line:GCT TIB-223)
- 10731-110B2
- 2379-69A1 (osteoclast, bone marrow derived)
Mouse (Mus musculus)
- 10704-109H2 (osteoclastoma cell line:Hs 706.T)
- 10711-109H9 (fibrous histiocytoma cell line:GCT TIB-223)
- 10731-110B2
- 2379-69A1 (osteoclast, bone marrow derived)
Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000092 (osteoclast), sorted by p-values
Analyst: Hideya Kawaji
link to source dataset
human : data
mouse : data
P-value | FFCP | Short description |
---|---|---|
1.55e-98 | FFCP PHASE2:Hg19::chr16:77317713..77317723,+#_b903eca76d53485a4f1d302a80ba1931 | p1@CU687665 |
1.55e-98 | FFCP PHASE1:Hg19::chr16:77317713..77317723,+#_b903eca76d53485a4f1d302a80ba1931 | p1@CU687665 |
1.55e-98 | FFCP PHASE2:Hg19::chr11:101742272..101742276,-#_b903eca76d53485a4f1d302a80ba1931 | p@chr11:101742272..101742276, - |
1.55e-98 | FFCP PHASE1:Hg19::chr11:101742272..101742276,-#_b903eca76d53485a4f1d302a80ba1931 | p@chr11:101742272..101742276, - |
2.74e-50 | FFCP PHASE1:Hg19::chr18:71197490..71197495,-#_33220fce424e59c6ca585a69a9fb1376 | p@chr18:71197490..71197495, - |
2.74e-50 | FFCP PHASE1:Hg19::chr5:14034644..14034647,-#_33220fce424e59c6ca585a69a9fb1376 | p@chr5:14034644..14034647, - |
2.74e-50 | FFCP PHASE2:Hg19::chr11:81551043..81551054,-#_33220fce424e59c6ca585a69a9fb1376 | p@chr11:81551043..81551054, - |
2.74e-50 | FFCP PHASE2:Hg19::chr16:51670868..51670880,-#_33220fce424e59c6ca585a69a9fb1376 | p@chr16:51670868..51670880, - |
2.74e-50 | FFCP PHASE1:Hg19::chr16:51670868..51670880,-#_33220fce424e59c6ca585a69a9fb1376 | p@chr16:51670868..51670880, - |
2.74e-50 | FFCP PHASE1:Hg19::chr11:81551043..81551054,-#_33220fce424e59c6ca585a69a9fb1376 | p@chr11:81551043..81551054, - |
2.74e-50 | FFCP PHASE2:Hg19::chr18:71197490..71197495,-#_33220fce424e59c6ca585a69a9fb1376 | p@chr18:71197490..71197495, - |
2.74e-50 | FFCP PHASE2:Hg19::chr5:14034644..14034647,-#_33220fce424e59c6ca585a69a9fb1376 | p@chr5:14034644..14034647, - |
4.52e-50 | FFCP PHASE1:Hg19::chr4:34480309..34480321,-#_bcc611bb0a9d91b1d95cfe9aa14af906 | p@chr4:34480309..34480321, - |
4.52e-50 | FFCP PHASE2:Hg19::chr4:34480309..34480321,-#_bcc611bb0a9d91b1d95cfe9aa14af906 | p@chr4:34480309..34480321, - |
4.52e-50 | FFCP PHASE2:Hg19::chr3:45174403..45174415,+#_bcc611bb0a9d91b1d95cfe9aa14af906 | p@chr3:45174403..45174415, + |
4.52e-50 | FFCP PHASE1:Hg19::chr3:106393655..106393659,+#_bcc611bb0a9d91b1d95cfe9aa14af906 | p@chr3:106393655..106393659, + |
4.52e-50 | FFCP PHASE2:Hg19::chr5:23952305..23952310,+#_bcc611bb0a9d91b1d95cfe9aa14af906 | p@chr5:23952305..23952310, + |
4.52e-50 | FFCP PHASE2:Hg19::chr3:106393655..106393659,+#_bcc611bb0a9d91b1d95cfe9aa14af906 | p@chr3:106393655..106393659, + |
4.52e-50 | FFCP PHASE1:Hg19::chr3:45174403..45174415,+#_bcc611bb0a9d91b1d95cfe9aa14af906 | p@chr3:45174403..45174415, + |
4.52e-50 | FFCP PHASE1:Hg19::chr5:23952305..23952310,+#_bcc611bb0a9d91b1d95cfe9aa14af906 | p@chr5:23952305..23952310, + |
3.61e-34 | FFCP PHASE1:Hg19::chr7:119353807..119353812,-#_c06849cd5e3fae14cd7426a8305dd2a6 | p@chr7:119353807..119353812, - |
3.61e-34 | FFCP PHASE2:Hg19::chr7:119353807..119353812,-#_c06849cd5e3fae14cd7426a8305dd2a6 | p@chr7:119353807..119353812, - |
3.61e-34 | FFCP PHASE1:Hg19::chr4:177796841..177796851,+#_c06849cd5e3fae14cd7426a8305dd2a6 | p1@ENST00000508790 |
3.61e-34 | FFCP PHASE2:Hg19::chr4:177796841..177796851,+#_c06849cd5e3fae14cd7426a8305dd2a6 | p1@ENST00000508790 |
5.04e-34 | FFCP PHASE1:Hg19::chr4:46093758..46093781,-#_d8e3c1647d49dfbb2f4c17d1404d654f | p@chr4:46093758..46093781, - |
5.04e-34 | FFCP PHASE1:Hg19::chr10:37004821..37004852,-#_d8e3c1647d49dfbb2f4c17d1404d654f | p@chr10:37004821..37004852, - |
5.04e-34 | FFCP PHASE2:Hg19::chr10:37004821..37004852,-#_d8e3c1647d49dfbb2f4c17d1404d654f | p@chr10:37004821..37004852, - |
5.04e-34 | FFCP PHASE2:Hg19::chrX:132231123..132231140,-#_d8e3c1647d49dfbb2f4c17d1404d654f | p1@USP26 |
5.04e-34 | FFCP PHASE2:Hg19::chr8:15939682..15939688,+#_d8e3c1647d49dfbb2f4c17d1404d654f | p@chr8:15939682..15939688, + |
5.04e-34 | FFCP PHASE2:Hg19::chr4:46093758..46093781,-#_d8e3c1647d49dfbb2f4c17d1404d654f | p@chr4:46093758..46093781, - |
5.04e-34 | FFCP PHASE1:Hg19::chr8:15939682..15939688,+#_d8e3c1647d49dfbb2f4c17d1404d654f | p@chr8:15939682..15939688, + |
5.04e-34 | FFCP PHASE1:Hg19::chrX:132231123..132231140,-#_d8e3c1647d49dfbb2f4c17d1404d654f | p1@USP26 |
7.05e-34 | FFCP PHASE2:Hg19::chr6:155427848..155427862,+#_85c553399eb943d9f9d14fe1e1033c67 | p@chr6:155427848..155427862, + |
7.05e-34 | FFCP PHASE1:Hg19::chr6:155427848..155427862,+#_85c553399eb943d9f9d14fe1e1033c67 | p@chr6:155427848..155427862, + |
7.05e-34 | FFCP PHASE2:Hg19::chrX:89462083..89462089,+#_85c553399eb943d9f9d14fe1e1033c67 | p@chrX:89462083..89462089, + |
7.05e-34 | FFCP PHASE1:Hg19::chrX:89462083..89462089,+#_85c553399eb943d9f9d14fe1e1033c67 | p@chrX:89462083..89462089, + |
7.05e-34 | FFCP PHASE2:Hg19::chr11:84019133..84019135,-#_85c553399eb943d9f9d14fe1e1033c67 | p@chr11:84019133..84019135, - |
7.05e-34 | FFCP PHASE1:Hg19::chr11:84019133..84019135,-#_85c553399eb943d9f9d14fe1e1033c67 | p@chr11:84019133..84019135, - |
5.5e-31 | FFCP PHASE2:Hg19::chr3:106556598..106556609,-#_f68521af51a91f3238c0e54fb137aa1e | -, p@chr3:106556598..106556609 |
5.5e-31 | FFCP PHASE1:Hg19::chr3:106556598..106556609,-#_f68521af51a91f3238c0e54fb137aa1e | p@chr3:106556598..106556609, - |
7.1e-28 | FFCP PHASE2:Hg19::chr6:68597008..68597030,-#_7e3f148977a24c49a4c7e2fb478f64d6 | p@chr6:68597008..68597030, - |
7.1e-28 | FFCP PHASE1:Hg19::chr6:68597008..68597030,-#_7e3f148977a24c49a4c7e2fb478f64d6 | p@chr6:68597008..68597030, - |
4.32e-26 | FFCP PHASE2:Hg19::chr11:81549961..81549965,-#_3d436b61f22464e3293afc5cb9600f13 | p@chr11:81549961..81549965, - |
4.32e-26 | FFCP PHASE1:Hg19::chr11:81549961..81549965,-#_3d436b61f22464e3293afc5cb9600f13 | p@chr11:81549961..81549965, - |
4.32e-26 | FFCP PHASE1:Hg19::chr5:27723923..27723927,-#_3d436b61f22464e3293afc5cb9600f13 | p@chr5:27723923..27723927, - |
4.32e-26 | FFCP PHASE2:Hg19::chr5:27723923..27723927,-#_3d436b61f22464e3293afc5cb9600f13 | -, p@chr5:27723923..27723927 |
5.56e-26 | FFCP PHASE1:Hg19::chrX:89176902..89176913,+#_fcf427a9031ef6a1f81ae8af91e0d2fd | p1@TGIF2LX |
5.56e-26 | FFCP PHASE2:Hg19::chr5:167315847..167315852,+#_fcf427a9031ef6a1f81ae8af91e0d2fd | p@chr5:167315847..167315852, + |
5.56e-26 | FFCP PHASE1:Hg19::chrX:124347061..124347063,-#_fcf427a9031ef6a1f81ae8af91e0d2fd | p@chrX:124347061..124347063, - |
5.56e-26 | FFCP PHASE1:Hg19::chr5:153673183..153673186,+#_fcf427a9031ef6a1f81ae8af91e0d2fd | p@chr5:153673183..153673186, + |
5.56e-26 | FFCP PHASE2:Hg19::chrX:89176902..89176913,+#_fcf427a9031ef6a1f81ae8af91e0d2fd | p1@TGIF2LX |
5.56e-26 | FFCP PHASE1:Hg19::chrX:132352373..132352384,-#_fcf427a9031ef6a1f81ae8af91e0d2fd | p1@TFDP3 |
5.56e-26 | FFCP PHASE1:Hg19::chr4:189864018..189864037,+#_fcf427a9031ef6a1f81ae8af91e0d2fd | p@chr4:189864018..189864037, + |
5.56e-26 | FFCP PHASE2:Hg19::chrX:124347061..124347063,-#_fcf427a9031ef6a1f81ae8af91e0d2fd | p@chrX:124347061..124347063, - |
5.56e-26 | FFCP PHASE2:Hg19::chr4:189864018..189864037,+#_fcf427a9031ef6a1f81ae8af91e0d2fd | p@chr4:189864018..189864037, + |
5.56e-26 | FFCP PHASE1:Hg19::chr5:167315847..167315852,+#_fcf427a9031ef6a1f81ae8af91e0d2fd | p@chr5:167315847..167315852, + |
5.56e-26 | FFCP PHASE2:Hg19::chrX:132352373..132352384,-#_fcf427a9031ef6a1f81ae8af91e0d2fd | p1@TFDP3 |
5.56e-26 | FFCP PHASE2:Hg19::chr5:153673183..153673186,+#_fcf427a9031ef6a1f81ae8af91e0d2fd | +, p@chr5:153673183..153673186 |
9.18e-26 | FFCP PHASE1:Hg19::chr18:14946224..14946236,+#_49480e96743bab033845ce4266ec09a5 | p1@FLJ44255 |
9.18e-26 | FFCP PHASE1:Hg19::chr7:12997533..12997536,+#_49480e96743bab033845ce4266ec09a5 | p@chr7:12997533..12997536, + |
9.18e-26 | FFCP PHASE2:Hg19::chr18:14946224..14946236,+#_49480e96743bab033845ce4266ec09a5 | p1@FLJ44255 |
9.18e-26 | FFCP PHASE2:Hg19::chr7:12997533..12997536,+#_49480e96743bab033845ce4266ec09a5 | p@chr7:12997533..12997536, + |
1.12e-25 | FFCP PHASE2:Hg19::chrX:55246809..55246816,+#_254b010d2b257690dc483a55542712c5 | p3@PAGE5 |
1.12e-25 | FFCP PHASE1:Hg19::chrX:55246809..55246816,+#_254b010d2b257690dc483a55542712c5 | p3@PAGE5 |
4.89e-23 | FFCP PHASE1:Hg19::chrX:55246818..55246829,+#_02f5a7edccb66aacd08df30b8950b7b4 | p2@PAGE5 |
4.89e-23 | FFCP PHASE2:Hg19::chrX:55246818..55246829,+#_02f5a7edccb66aacd08df30b8950b7b4 | p2@PAGE5 |
3.11e-21 | FFCP PHASE2:Hg19::chr5:27742047..27742052,-#_23a75e50def3185ec34c6e75eda71a15 | p@chr5:27742047..27742052, - |
3.11e-21 | FFCP PHASE2:Hg19::chr12:127737083..127737103,-#_23a75e50def3185ec34c6e75eda71a15 | p@chr12:127737083..127737103, - |
3.11e-21 | FFCP PHASE1:Hg19::chr5:27742047..27742052,-#_23a75e50def3185ec34c6e75eda71a15 | p@chr5:27742047..27742052, - |
3.11e-21 | FFCP PHASE1:Hg19::chr12:127737083..127737103,-#_23a75e50def3185ec34c6e75eda71a15 | p@chr12:127737083..127737103, - |
3.11e-21 | FFCP PHASE1:Hg19::chr8:119905427..119905438,-#_23a75e50def3185ec34c6e75eda71a15 | p@chr8:119905427..119905438, - |
3.11e-21 | FFCP PHASE2:Hg19::chr8:119905427..119905438,-#_23a75e50def3185ec34c6e75eda71a15 | p@chr8:119905427..119905438, - |
3.81e-21 | FFCP PHASE1:Hg19::chr13:87732242..87732246,-#_71c506c94b939e7505d1010920c0a5cb | p@chr13:87732242..87732246, - |
3.81e-21 | FFCP PHASE1:Hg19::chr19:9811101..9811112,-#_71c506c94b939e7505d1010920c0a5cb | p3@ZNF812 |
3.81e-21 | FFCP PHASE1:Hg19::chr9:118595109..118595124,+#_71c506c94b939e7505d1010920c0a5cb | p@chr9:118595109..118595124, + |
3.81e-21 | FFCP PHASE2:Hg19::chr13:87732242..87732246,-#_71c506c94b939e7505d1010920c0a5cb | p@chr13:87732242..87732246, - |
3.81e-21 | FFCP PHASE2:Hg19::chr5:135378750..135378757,+#_71c506c94b939e7505d1010920c0a5cb | p@chr5:135378750..135378757, + |
3.81e-21 | FFCP PHASE2:Hg19::chr2:145815206..145815208,+#_71c506c94b939e7505d1010920c0a5cb | p@chr2:145815206..145815208, + |
3.81e-21 | FFCP PHASE2:Hg19::chr9:118595109..118595124,+#_71c506c94b939e7505d1010920c0a5cb | p@chr9:118595109..118595124, + |
3.81e-21 | FFCP PHASE2:Hg19::chr19:9811101..9811112,-#_71c506c94b939e7505d1010920c0a5cb | p3@ZNF812 |
3.81e-21 | FFCP PHASE1:Hg19::chr5:135378750..135378757,+#_71c506c94b939e7505d1010920c0a5cb | p@chr5:135378750..135378757, + |
3.81e-21 | FFCP PHASE1:Hg19::chr2:145815206..145815208,+#_71c506c94b939e7505d1010920c0a5cb | p@chr2:145815206..145815208, + |
4.66e-21 | FFCP PHASE2:Hg19::chrX:140336680..140336697,-#_9c0b0d452b1dad3af03606a959be177f | p2@SPANXC |
4.66e-21 | FFCP PHASE1:Hg19::chrX:140336680..140336697,-#_9c0b0d452b1dad3af03606a959be177f | p2@SPANXC |
5.7e-21 | FFCP PHASE2:Hg19::chr2:33171944..33171945,+#_8540f02e5c5ad9ca3af574841967f8a4 | p15@LTBP1 |
5.7e-21 | FFCP PHASE1:Hg19::chr2:33171944..33171945,+#_8540f02e5c5ad9ca3af574841967f8a4 | p15@LTBP1 |
5.7e-21 | FFCP PHASE1:Hg19::chr5:142000787..142000807,-#_8540f02e5c5ad9ca3af574841967f8a4 | p@chr5:142000787..142000807, - |
5.7e-21 | FFCP PHASE2:Hg19::chr5:142000787..142000807,-#_8540f02e5c5ad9ca3af574841967f8a4 | p@chr5:142000787..142000807, - |
6.96e-21 | FFCP PHASE1:Hg19::chr11:12061317..12061323,-#_9878b9d457bc8a70757269c025f120b6 | p@chr11:12061317..12061323, - |
6.96e-21 | FFCP PHASE2:Hg19::chr11:28792916..28792929,+#_9878b9d457bc8a70757269c025f120b6 | p@chr11:28792916..28792929, + |
6.96e-21 | FFCP PHASE1:Hg19::chr11:28792916..28792929,+#_9878b9d457bc8a70757269c025f120b6 | p@chr11:28792916..28792929, + |
6.96e-21 | FFCP PHASE1:Hg19::chr5:81611412..81611423,+#_9878b9d457bc8a70757269c025f120b6 | p@chr5:81611412..81611423, + |
6.96e-21 | FFCP PHASE2:Hg19::chr18:63273310..63273317,+#_9878b9d457bc8a70757269c025f120b6 | p@chr18:63273310..63273317, + |
6.96e-21 | FFCP PHASE1:Hg19::chr8:76774227..76774234,+#_9878b9d457bc8a70757269c025f120b6 | p@chr8:76774227..76774234, + |
6.96e-21 | FFCP PHASE2:Hg19::chr3:60761167..60761179,+#_9878b9d457bc8a70757269c025f120b6 | p@chr3:60761167..60761179, + |
6.96e-21 | FFCP PHASE2:Hg19::chr8:76774227..76774234,+#_9878b9d457bc8a70757269c025f120b6 | +, p@chr8:76774227..76774234 |
6.96e-21 | FFCP PHASE1:Hg19::chr3:60761167..60761179,+#_9878b9d457bc8a70757269c025f120b6 | p@chr3:60761167..60761179, + |
6.96e-21 | FFCP PHASE2:Hg19::chr5:81611412..81611423,+#_9878b9d457bc8a70757269c025f120b6 | p@chr5:81611412..81611423, + |
6.96e-21 | FFCP PHASE1:Hg19::chr18:63273310..63273317,+#_9878b9d457bc8a70757269c025f120b6 | p@chr18:63273310..63273317, + |
6.96e-21 | FFCP PHASE2:Hg19::chr11:12061317..12061323,-#_9878b9d457bc8a70757269c025f120b6 | p@chr11:12061317..12061323, - |