CL:0000235
From FANTOM5_SSTAR
Name: | macrophage | ||
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Namespace: | FANTOM | ||
Definition: | "A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells." [GO_REF:0000031, GOC:add, GOC:tfm, http://www.clt.astate.edu/wwilliam/, PMID:16213494, PMID:1919437] | ||
Xrefs: |
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Synonyms: | "histiocyte" EXACT [] | ||
Comments: | Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid. |
Ontology association
Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.
link to ontology dataset
data
Parents
is_a: | CL:0000234(phagocyte),CL:0000766(myeloid leukocyte) |
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develops_from: | CL:0000576(monocyte) |
Children
is a: | CL:0000864 (tissue-resident macrophage) |
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derives from: | FF:0000086 (human macrophage sample),FF:0200001 (macrophage, TB infection sample) |
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples
It includes FANTOM5 samples that overlay the Cell ontology.
Human (Homo sapiens)
- 11232-116C8 (Macrophage - monocyte derived, donor1)
- 11313-117C8 (Macrophage - monocyte derived, donor2)
- 11389-118C3 (Macrophage - monocyte derived, donor3)
- 11501-119F7
- 11641-122D3 (Mouse Microglia, donor3)
- 11662-122F6
- 11718-123C8 (Mouse Microglia, donor1)
- 11736-123E8 (Mouse Microglia, donor2)
- 12698-135D7 (Monocyte-derived macrophages response to LPS)
- 12699-135D8 (Monocyte-derived macrophages response to LPS, 00hr15min, donor1 (t2 Subject1))
... further results Mouse (Mus musculus)
- 11232-116C8 (Macrophage - monocyte derived, donor1)
- 11313-117C8 (Macrophage - monocyte derived, donor2)
- 11389-118C3 (Macrophage - monocyte derived, donor3)
- 11501-119F7
- 11641-122D3 (Mouse Microglia, donor3)
- 11662-122F6
- 11718-123C8 (Mouse Microglia, donor1)
- 11736-123E8 (Mouse Microglia, donor2)
- 12698-135D7 (Monocyte-derived macrophages response to LPS)
- 12699-135D8 (Monocyte-derived macrophages response to LPS, 00hr15min, donor1 (t2 Subject1))
Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000235 (macrophage), sorted by p-values
Analyst: Hideya Kawaji
link to source dataset
human : data
mouse : data
P-value | FFCP | Short description |
---|---|---|
2.37e-195 | FFCP PHASE2:Hg19::chr20:44640347..44640359,+#_1b6c67710e2aeff5edb084b7ff71cd57 | p11@MMP9 |
2.37e-195 | FFCP PHASE2:Hg19::chr20:44641953..44641968,+#_1b6c67710e2aeff5edb084b7ff71cd57 | p@chr20:44641953..44641968, + |
2.37e-195 | FFCP PHASE2:Hg19::chr20:44639118..44639130,+#_1b6c67710e2aeff5edb084b7ff71cd57 | p@chr20:44639118..44639130, + |
2.37e-195 | FFCP PHASE2:Hg19::chr20:44638551..44638562,+#_1b6c67710e2aeff5edb084b7ff71cd57 | p@chr20:44638551..44638562, + |
2.37e-195 | FFCP PHASE1:Hg19::chr20:44640347..44640359,+#_1b6c67710e2aeff5edb084b7ff71cd57 | p11@MMP9 |
2.37e-195 | FFCP PHASE1:Hg19::chr20:44641953..44641968,+#_1b6c67710e2aeff5edb084b7ff71cd57 | p@chr20:44641953..44641968, + |
2.37e-195 | FFCP PHASE1:Hg19::chr20:44639118..44639130,+#_1b6c67710e2aeff5edb084b7ff71cd57 | p@chr20:44639118..44639130, + |
2.37e-195 | FFCP PHASE1:Hg19::chr20:44638551..44638562,+#_1b6c67710e2aeff5edb084b7ff71cd57 | p@chr20:44638551..44638562, + |
5.73e-168 | FFCP PHASE1:Hg19::chr20:44638694..44638710,+#_ef1822b7512b17d46108cdf297257c23 | p@chr20:44638694..44638710, + |
5.73e-168 | FFCP PHASE2:Hg19::chr20:44638633..44638646,+#_ef1822b7512b17d46108cdf297257c23 | p@chr20:44638633..44638646, + |
5.73e-168 | FFCP PHASE1:Hg19::chr20:44638717..44638738,-#_ef1822b7512b17d46108cdf297257c23 | p@chr20:44638717..44638738, - |
5.73e-168 | FFCP PHASE2:Hg19::chr20:44638694..44638710,+#_ef1822b7512b17d46108cdf297257c23 | p@chr20:44638694..44638710, + |
5.73e-168 | FFCP PHASE1:Hg19::chr20:44638633..44638646,+#_ef1822b7512b17d46108cdf297257c23 | p@chr20:44638633..44638646, + |
5.73e-168 | FFCP PHASE2:Hg19::chr20:44638717..44638738,-#_ef1822b7512b17d46108cdf297257c23 | p@chr20:44638717..44638738, - |
7.64e-168 | FFCP PHASE1:Hg19::chr20:44638515..44638530,+#_89572743b093fd89ba9bfb7d604d7385 | p@chr20:44638515..44638530, + |
7.64e-168 | FFCP PHASE2:Hg19::chr20:44638515..44638530,+#_89572743b093fd89ba9bfb7d604d7385 | p@chr20:44638515..44638530, + |
1.02e-167 | FFCP PHASE1:Hg19::chr20:44645128..44645150,+#_bf802cdba157b0fb27b33b4f7e28cb5c | p@chr20:44645128..44645150, + |
1.02e-167 | FFCP PHASE1:Hg19::chr20:44640312..44640322,+#_bf802cdba157b0fb27b33b4f7e28cb5c | p10@MMP9 |
1.02e-167 | FFCP PHASE2:Hg19::chr20:44642333..44642369,+#_bf802cdba157b0fb27b33b4f7e28cb5c | p@chr20:44642333..44642369, + |
1.02e-167 | FFCP PHASE2:Hg19::chr20:44645128..44645150,+#_bf802cdba157b0fb27b33b4f7e28cb5c | p@chr20:44645128..44645150, + |
1.02e-167 | FFCP PHASE2:Hg19::chr20:44640312..44640322,+#_bf802cdba157b0fb27b33b4f7e28cb5c | p10@MMP9 |
1.02e-167 | FFCP PHASE1:Hg19::chr20:44642333..44642369,+#_bf802cdba157b0fb27b33b4f7e28cb5c | p@chr20:44642333..44642369, + |
5.41e-163 | FFCP PHASE1:Hg19::chr20:44640866..44640875,-#_ad3ea0be2280eecaa4dfcd97ce8f79af | p@chr20:44640866..44640875, - |
5.41e-163 | FFCP PHASE2:Hg19::chr20:44640304..44640310,+#_ad3ea0be2280eecaa4dfcd97ce8f79af | p13@MMP9 |
5.41e-163 | FFCP PHASE1:Hg19::chr20:44638625..44638633,-#_ad3ea0be2280eecaa4dfcd97ce8f79af | p@chr20:44638625..44638633, - |
5.41e-163 | FFCP PHASE2:Hg19::chr20:44640866..44640875,-#_ad3ea0be2280eecaa4dfcd97ce8f79af | p@chr20:44640866..44640875, - |
5.41e-163 | FFCP PHASE1:Hg19::chr20:44640304..44640310,+#_ad3ea0be2280eecaa4dfcd97ce8f79af | p13@MMP9 |
5.41e-163 | FFCP PHASE2:Hg19::chr20:44638625..44638633,-#_ad3ea0be2280eecaa4dfcd97ce8f79af | -, p@chr20:44638625..44638633 |
1.99e-147 | FFCP PHASE2:Hg19::chr20:44639634..44639645,+#_38f35c6691261d45b7860f0835be0f85 | p@chr20:44639634..44639645, + |
1.99e-147 | FFCP PHASE1:Hg19::chr20:44638500..44638512,+#_38f35c6691261d45b7860f0835be0f85 | p@chr20:44638500..44638512, + |
1.99e-147 | FFCP PHASE2:Hg19::chr20:44640269..44640283,+#_38f35c6691261d45b7860f0835be0f85 | p7@MMP9 |
1.99e-147 | FFCP PHASE1:Hg19::chr20:44639634..44639645,+#_38f35c6691261d45b7860f0835be0f85 | p@chr20:44639634..44639645, + |
1.99e-147 | FFCP PHASE2:Hg19::chr20:44638500..44638512,+#_38f35c6691261d45b7860f0835be0f85 | +, p@chr20:44638500..44638512 |
1.99e-147 | FFCP PHASE1:Hg19::chr20:44640269..44640283,+#_38f35c6691261d45b7860f0835be0f85 | p7@MMP9 |
2.56e-147 | FFCP PHASE1:Hg19::chr20:44638613..44638632,+#_9962213947827c29fc3c494f47f527a7 | p@chr20:44638613..44638632, + |
2.56e-147 | FFCP PHASE2:Hg19::chr20:44638566..44638579,+#_9962213947827c29fc3c494f47f527a7 | p@chr20:44638566..44638579, + |
2.56e-147 | FFCP PHASE2:Hg19::chr20:44638613..44638632,+#_9962213947827c29fc3c494f47f527a7 | p@chr20:44638613..44638632, + |
2.56e-147 | FFCP PHASE1:Hg19::chr20:44638566..44638579,+#_9962213947827c29fc3c494f47f527a7 | p@chr20:44638566..44638579, + |
5.45e-147 | FFCP PHASE2:Hg19::chr20:44639771..44639782,+#_5928f006d1ec65317ca25577abb2d92f | p@chr20:44639771..44639782, + |
5.45e-147 | FFCP PHASE1:Hg19::chr20:44639771..44639782,+#_5928f006d1ec65317ca25577abb2d92f | p@chr20:44639771..44639782, + |
7.01e-147 | FFCP PHASE1:Hg19::chr20:44641138..44641146,+#_61ea002cba5ccb1f22f03072ebc78f82 | p@chr20:44641138..44641146, + |
7.01e-147 | FFCP PHASE2:Hg19::chr20:44641138..44641146,+#_61ea002cba5ccb1f22f03072ebc78f82 | p@chr20:44641138..44641146, + |
3.49e-136 | FFCP PHASE1:Hg19::chr20:44639929..44639935,+#_2de983a9177354a727868f6ad017199e | p@chr20:44639929..44639935, + |
3.49e-136 | FFCP PHASE2:Hg19::chr20:44639929..44639935,+#_2de983a9177354a727868f6ad017199e | p@chr20:44639929..44639935, + |
4.61e-136 | FFCP PHASE2:Hg19::chr9:86983573..86983587,-#_ab0c398acde8e81034657cf57d72eabd | p6@SLC28A3 |
4.61e-136 | FFCP PHASE1:Hg19::chr9:86983573..86983587,-#_ab0c398acde8e81034657cf57d72eabd | p6@SLC28A3 |
1.89e-131 | FFCP PHASE1:Hg19::chr20:44639910..44639947,-#_a9d2fa14160aaba1a9dec28f7c706882 | p@chr20:44639910..44639947, - |
1.89e-131 | FFCP PHASE1:Hg19::chr20:44639149..44639161,+#_a9d2fa14160aaba1a9dec28f7c706882 | p@chr20:44639149..44639161, + |
1.89e-131 | FFCP PHASE2:Hg19::chr20:44639910..44639947,-#_a9d2fa14160aaba1a9dec28f7c706882 | p@chr20:44639910..44639947, - |
1.89e-131 | FFCP PHASE2:Hg19::chr20:44639149..44639161,+#_a9d2fa14160aaba1a9dec28f7c706882 | p@chr20:44639149..44639161, + |
5.81e-131 | FFCP PHASE1:Hg19::chr20:44641166..44641180,+#_e61b1dab2458e8334efb89215601b20e | p@chr20:44641166..44641180, + |
5.81e-131 | FFCP PHASE2:Hg19::chr20:44641166..44641180,+#_e61b1dab2458e8334efb89215601b20e | p@chr20:44641166..44641180, + |
1.07e-130 | FFCP PHASE2:Hg19::chr6:164082461..164082467,-#_ccbd6d4b303530e41efaf16c5030b331 | p@chr6:164082461..164082467, - |
1.07e-130 | FFCP PHASE1:Hg19::chr5:147789958..147789969,+#_ccbd6d4b303530e41efaf16c5030b331 | p5@FBXO38 |
1.07e-130 | FFCP PHASE2:Hg19::chr5:147789958..147789969,+#_ccbd6d4b303530e41efaf16c5030b331 | p5@FBXO38 |
1.07e-130 | FFCP PHASE1:Hg19::chr6:164082461..164082467,-#_ccbd6d4b303530e41efaf16c5030b331 | p@chr6:164082461..164082467, - |
1.15e-118 | FFCP PHASE1:Hg19::chr20:44639584..44639604,+#_c68de898b87ba5530c1d3b49f5c47e53 | p@chr20:44639584..44639604, + |
1.15e-118 | FFCP PHASE2:Hg19::chr20:44638657..44638691,+#_c68de898b87ba5530c1d3b49f5c47e53 | p@chr20:44638657..44638691, + |
1.15e-118 | FFCP PHASE2:Hg19::chr20:44639584..44639604,+#_c68de898b87ba5530c1d3b49f5c47e53 | p@chr20:44639584..44639604, + |
1.15e-118 | FFCP PHASE1:Hg19::chr20:44638657..44638691,+#_c68de898b87ba5530c1d3b49f5c47e53 | p@chr20:44638657..44638691, + |
1.73e-118 | FFCP PHASE2:Hg19::chr20:44641061..44641077,+#_4c88df6ec7625d65a009554c1b7193b2 | p@chr20:44641061..44641077, + |
1.73e-118 | FFCP PHASE1:Hg19::chr20:44641061..44641077,+#_4c88df6ec7625d65a009554c1b7193b2 | p@chr20:44641061..44641077, + |
4.35e-117 | FFCP PHASE2:Hg19::chr14:61452664..61452679,+#_deb102209832f851df239d27d62cb1fd | p@chr14:61452664..61452679, + |
4.35e-117 | FFCP PHASE1:Hg19::chrX:46639989..46640013,-#_deb102209832f851df239d27d62cb1fd | p@chrX:46639989..46640013, - |
4.35e-117 | FFCP PHASE2:Hg19::chrX:46639989..46640013,-#_deb102209832f851df239d27d62cb1fd | p@chrX:46639989..46640013, - |
4.35e-117 | FFCP PHASE1:Hg19::chr14:61452664..61452679,+#_deb102209832f851df239d27d62cb1fd | p@chr14:61452664..61452679, + |
4.98e-117 | FFCP PHASE2:Hg19::chr20:44639896..44639903,+#_978d2f722ce0dfa64f3eb042ff33822a | p@chr20:44639896..44639903, + |
4.98e-117 | FFCP PHASE1:Hg19::chr20:44639896..44639903,+#_978d2f722ce0dfa64f3eb042ff33822a | p@chr20:44639896..44639903, + |
8.05e-117 | FFCP PHASE1:Hg19::chr6:4347006..4347027,-#_d5fafda2dbb434ecc724e134e89ebbf8 | p@chr6:4347006..4347027, - |
8.05e-117 | FFCP PHASE2:Hg19::chr6:4347006..4347027,-#_d5fafda2dbb434ecc724e134e89ebbf8 | -, p@chr6:4347006..4347027 |
5.81e-108 | FFCP PHASE2:Hg19::chr20:44640829..44640856,+#_8165ebdcec529dacc0596359cb178de4 | p4@MMP9 |
5.81e-108 | FFCP PHASE1:Hg19::chr20:44640829..44640856,+#_8165ebdcec529dacc0596359cb178de4 | p4@MMP9 |
2.53e-107 | FFCP PHASE1:Hg19::chr8:24256905..24256914,+#_45fecd9dfd55e0c0ed2464e5389beeb2 | p@chr8:24256905..24256914, + |
2.53e-107 | FFCP PHASE2:Hg19::chr8:24256905..24256914,+#_45fecd9dfd55e0c0ed2464e5389beeb2 | p@chr8:24256905..24256914, + |
3.04e-107 | FFCP PHASE2:Hg19::chr7:137308..137321,+#_69c9cb29dd6614e8dc44ac923979ba13 | p@chr7:137308..137321, + |
3.04e-107 | FFCP PHASE1:Hg19::chr7:137308..137321,+#_69c9cb29dd6614e8dc44ac923979ba13 | p@chr7:137308..137321, + |
6.32e-107 | FFCP PHASE1:Hg19::chr19:45418067..45418076,+#_947633915711acf39a6e735aa87087e6 | p7@APOC1 |
6.32e-107 | FFCP PHASE2:Hg19::chr19:45418067..45418076,+#_947633915711acf39a6e735aa87087e6 | p7@APOC1 |
7.59e-107 | FFCP PHASE2:Hg19::chr6:46700055..46700067,-#_19c52bcdc4955a5dd9520cb5d180fc10 | p@chr6:46700055..46700067, - |
7.59e-107 | FFCP PHASE1:Hg19::chr6:46700055..46700067,-#_19c52bcdc4955a5dd9520cb5d180fc10 | p@chr6:46700055..46700067, - |
6.76e-105 | FFCP PHASE2:Hg19::chr17:62315972..62315978,-#_021d3f5a9c8a464bd65df08ab4fbabe1 | p@chr17:62315972..62315978, - |
6.76e-105 | FFCP PHASE1:Hg19::chr17:62315972..62315978,-#_021d3f5a9c8a464bd65df08ab4fbabe1 | p@chr17:62315972..62315978, - |
5.07e-102 | FFCP PHASE2:Hg19::chr17:29281302..29281321,+#_aeecea40033812b82c371ed766522dbb | p6@ADAP2 |
5.07e-102 | FFCP PHASE1:Hg19::chr17:29281302..29281321,+#_aeecea40033812b82c371ed766522dbb | p6@ADAP2 |
1.44e-101 | FFCP PHASE2:Hg19::chr5:150873510..150873548,+#_3a5ea8d82598857fa6ec684560490e89 | p@chr5:150873510..150873548, + |
1.44e-101 | FFCP PHASE1:Hg19::chr5:150873510..150873548,+#_3a5ea8d82598857fa6ec684560490e89 | p@chr5:150873510..150873548, + |
1.76e-99 | FFCP PHASE2:Hg19::chr20:44641085..44641097,+#_a516629f939638c41f9c12760f4ca6d9 | p@chr20:44641085..44641097, + |
1.76e-99 | FFCP PHASE2:Hg19::chr20:44639906..44639917,+#_a516629f939638c41f9c12760f4ca6d9 | p@chr20:44639906..44639917, + |
1.76e-99 | FFCP PHASE2:Hg19::chr20:44639141..44639152,-#_a516629f939638c41f9c12760f4ca6d9 | p@chr20:44639141..44639152, - |
1.76e-99 | FFCP PHASE1:Hg19::chr20:44641085..44641097,+#_a516629f939638c41f9c12760f4ca6d9 | p@chr20:44641085..44641097, + |
1.76e-99 | FFCP PHASE1:Hg19::chr20:44639906..44639917,+#_a516629f939638c41f9c12760f4ca6d9 | p@chr20:44639906..44639917, + |
1.76e-99 | FFCP PHASE1:Hg19::chr20:44639141..44639152,-#_a516629f939638c41f9c12760f4ca6d9 | p@chr20:44639141..44639152, - |
1.83e-98 | FFCP PHASE1:Hg19::chr6:4346987..4346998,-#_3bc0af37f50f6166a31b0f14829ba06d | p@chr6:4346987..4346998, - |
1.83e-98 | FFCP PHASE2:Hg19::chr20:44638538..44638547,-#_3bc0af37f50f6166a31b0f14829ba06d | p@chr20:44638538..44638547, - |
1.83e-98 | FFCP PHASE2:Hg19::chr1:156510852..156510859,-#_3bc0af37f50f6166a31b0f14829ba06d | p@chr1:156510852..156510859, - |
1.83e-98 | FFCP PHASE2:Hg19::chr6:4346987..4346998,-#_3bc0af37f50f6166a31b0f14829ba06d | p@chr6:4346987..4346998, - |
1.83e-98 | FFCP PHASE1:Hg19::chr20:44639616..44639619,+#_3bc0af37f50f6166a31b0f14829ba06d | p@chr20:44639616..44639619, + |
1.83e-98 | FFCP PHASE1:Hg19::chr6:164082477..164082487,-#_3bc0af37f50f6166a31b0f14829ba06d | p@chr6:164082477..164082487, - |
1.83e-98 | FFCP PHASE1:Hg19::chr20:44639171..44639178,+#_3bc0af37f50f6166a31b0f14829ba06d | p@chr20:44639171..44639178, + |
1.83e-98 | FFCP PHASE1:Hg19::chr20:44638538..44638547,-#_3bc0af37f50f6166a31b0f14829ba06d | p@chr20:44638538..44638547, - |