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CL:0001014

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Name:CD1a-positive Langerhans cell
Namespace:FANTOM
Definition:"CD1a-positive Langerhans cell is a Langerhans_cell that is CD1a-positive and CD324-positive." [GO_REF:0000031, GOC:amm, PMID:17850486]
Synonyms: "CD1a-LC" EXACT []
Comments:These markers are associated with human cells. Originally described in the dendritic cell ontology (DC_CL:0000026)(PMID: 19243617). These cells are also CD281-positive (TLR1), CD282-positive (TLR2), CD284-positive (TLR4), CD286-positive (TLR6), CD287-positive (TLR7), and CD290-positive (TLR10). When activated, these cells are capable of producing IL-6, IL-8, and IL-15.


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:CL:0000453(Langerhans cell)



Children


is a:CL:0001016 (immature CD1a-positive Langerhans cell)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.


Human (Homo sapiens)

Mouse (Mus musculus)


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0001014 (CD1a-positive Langerhans cell), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data


P-valueFFCPShort description
3.29e-195FFCP PHASE1:Hg19::chr2:71058922..71058927,-#_d7ef70998e117c30b280d3c550b22420p@chr2:71058922..71058927, -
3.29e-195FFCP PHASE1:Hg19::chr17:817943..817953,-#_d7ef70998e117c30b280d3c550b22420p@chr17:817943..817953, -
3.29e-195FFCP PHASE1:Hg19::chr19:6063965..6063994,+#_d7ef70998e117c30b280d3c550b22420p@chr19:6063965..6063994, +
3.29e-195FFCP PHASE1:Hg19::chr3:7961529..7961534,-#_d7ef70998e117c30b280d3c550b22420p@chr3:7961529..7961534, -
3.29e-195FFCP PHASE1:Hg19::chr7:20479783..20479785,-#_d7ef70998e117c30b280d3c550b22420p@chr7:20479783..20479785, -
3.29e-195FFCP PHASE1:Hg19::chr6:10529918..10529924,+#_d7ef70998e117c30b280d3c550b22420p31@GCNT2
3.29e-195FFCP PHASE2:Hg19::chr19:35485281..35485283,+#_d7ef70998e117c30b280d3c550b22420p20@GRAMD1A
3.29e-195FFCP PHASE1:Hg19::chr20:62482031..62482052,-#_d7ef70998e117c30b280d3c550b22420p@chr20:62482031..62482052, -
3.29e-195FFCP PHASE1:Hg19::chr8:21039080..21039110,+#_d7ef70998e117c30b280d3c550b22420p@chr8:21039080..21039110, +
3.29e-195FFCP PHASE2:Hg19::chr2:71057873..71057874,-#_d7ef70998e117c30b280d3c550b22420p@chr2:71057873..71057874, -
3.29e-195FFCP PHASE2:Hg19::chr18:53545759..53545802,+#_d7ef70998e117c30b280d3c550b22420p@chr18:53545759..53545802, +
3.29e-195FFCP PHASE1:Hg19::chr14:69223811..69223817,+#_d7ef70998e117c30b280d3c550b22420p@chr14:69223811..69223817, +
3.29e-195FFCP PHASE2:Hg19::chr1:117087402..117087404,+#_d7ef70998e117c30b280d3c550b22420p@chr1:117087402..117087404, +
3.29e-195FFCP PHASE2:Hg19::chr2:135821386..135821432,+#_d7ef70998e117c30b280d3c550b22420p@chr2:135821386..135821432, +
3.29e-195FFCP PHASE1:Hg19::chr20:1762918..1762921,-#_d7ef70998e117c30b280d3c550b22420p@chr20:1762918..1762921, -
3.29e-195FFCP PHASE1:Hg19::chr10:81701830..81701837,-#_d7ef70998e117c30b280d3c550b22420p@chr10:81701830..81701837, -
3.29e-195FFCP PHASE2:Hg19::chr6:33084930..33084937,+#_d7ef70998e117c30b280d3c550b22420p@chr6:33084930..33084937, +
3.29e-195FFCP PHASE2:Hg19::chr20:44639733..44639737,+#_d7ef70998e117c30b280d3c550b22420p@chr20:44639733..44639737, +
3.29e-195FFCP PHASE2:Hg19::chr14:69223811..69223817,+#_d7ef70998e117c30b280d3c550b22420p@chr14:69223811..69223817, +
3.29e-195FFCP PHASE1:Hg19::chr3:7961538..7961548,-#_d7ef70998e117c30b280d3c550b22420p@chr3:7961538..7961548, -
3.29e-195FFCP PHASE2:Hg19::chr1:229182544..229182560,-#_d7ef70998e117c30b280d3c550b22420p@chr1:229182544..229182560, -
3.29e-195FFCP PHASE2:Hg19::chr10:81701830..81701837,-#_d7ef70998e117c30b280d3c550b22420p@chr10:81701830..81701837, -
3.29e-195FFCP PHASE2:Hg19::chr10:95326623..95326652,+#_d7ef70998e117c30b280d3c550b22420p3@O3FAR1
3.29e-195FFCP PHASE1:Hg19::chr13:100018656..100018672,+#_d7ef70998e117c30b280d3c550b22420p@chr13:100018656..100018672, +
3.29e-195FFCP PHASE2:Hg19::chr2:71058922..71058927,-#_d7ef70998e117c30b280d3c550b22420p@chr2:71058922..71058927, -
3.29e-195FFCP PHASE1:Hg19::chr2:242169538..242169541,-#_d7ef70998e117c30b280d3c550b22420p71@HDLBP
3.29e-195FFCP PHASE2:Hg19::chr7:111726632..111726641,-#_d7ef70998e117c30b280d3c550b22420p@chr7:111726632..111726641, -
3.29e-195FFCP PHASE1:Hg19::chr19:35485281..35485283,+#_d7ef70998e117c30b280d3c550b22420p20@GRAMD1A
3.29e-195FFCP PHASE1:Hg19::chr13:42969602..42969625,-#_d7ef70998e117c30b280d3c550b22420p@chr13:42969602..42969625, -
3.29e-195FFCP PHASE2:Hg19::chr11:109958698..109958703,-#_d7ef70998e117c30b280d3c550b22420p@chr11:109958698..109958703, -
3.29e-195FFCP PHASE2:Hg19::chr17:817943..817953,-#_d7ef70998e117c30b280d3c550b22420p@chr17:817943..817953, -
3.29e-195FFCP PHASE2:Hg19::chr3:7961529..7961534,-#_d7ef70998e117c30b280d3c550b22420p@chr3:7961529..7961534, -
3.29e-195FFCP PHASE2:Hg19::chr7:20479783..20479785,-#_d7ef70998e117c30b280d3c550b22420p@chr7:20479783..20479785, -
3.29e-195FFCP PHASE2:Hg19::chr12:112587704..112587710,+#_d7ef70998e117c30b280d3c550b22420p@chr12:112587704..112587710, +
3.29e-195FFCP PHASE2:Hg19::chr13:100018656..100018672,+#_d7ef70998e117c30b280d3c550b22420p@chr13:100018656..100018672, +
3.29e-195FFCP PHASE2:Hg19::chr6:10529918..10529924,+#_d7ef70998e117c30b280d3c550b22420p31@GCNT2
3.29e-195FFCP PHASE1:Hg19::chr1:117087402..117087404,+#_d7ef70998e117c30b280d3c550b22420p@chr1:117087402..117087404, +
3.29e-195FFCP PHASE2:Hg19::chr13:42969602..42969625,-#_d7ef70998e117c30b280d3c550b22420p@chr13:42969602..42969625, -
3.29e-195FFCP PHASE1:Hg19::chr16:33722353..33722359,+#_d7ef70998e117c30b280d3c550b22420p@chr16:33722353..33722359, +
3.29e-195FFCP PHASE2:Hg19::chr1:229182571..229182583,-#_d7ef70998e117c30b280d3c550b22420p@chr1:229182571..229182583, -
3.29e-195FFCP PHASE2:Hg19::chr18:46523734..46523740,+#_d7ef70998e117c30b280d3c550b22420p@chr18:46523734..46523740, +
3.29e-195FFCP PHASE1:Hg19::chr20:44639733..44639737,+#_d7ef70998e117c30b280d3c550b22420p@chr20:44639733..44639737, +
3.29e-195FFCP PHASE2:Hg19::chr8:21039080..21039110,+#_d7ef70998e117c30b280d3c550b22420p@chr8:21039080..21039110, +
3.29e-195FFCP PHASE2:Hg19::chr16:33722353..33722359,+#_d7ef70998e117c30b280d3c550b22420p@chr16:33722353..33722359, +
3.29e-195FFCP PHASE1:Hg19::chr9:8384123..8384141,-#_d7ef70998e117c30b280d3c550b22420p@chr9:8384123..8384141, -
3.29e-195FFCP PHASE1:Hg19::chr1:229182544..229182560,-#_d7ef70998e117c30b280d3c550b22420p@chr1:229182544..229182560, -
3.29e-195FFCP PHASE1:Hg19::chr18:53545728..53545733,+#_d7ef70998e117c30b280d3c550b22420p@chr18:53545728..53545733, +
3.29e-195FFCP PHASE1:Hg19::chr2:71057780..71057794,-#_d7ef70998e117c30b280d3c550b22420p@chr2:71057780..71057794, -
3.29e-195FFCP PHASE1:Hg19::chr6:4337610..4337616,+#_d7ef70998e117c30b280d3c550b22420p@chr6:4337610..4337616, +
3.29e-195FFCP PHASE1:Hg19::chr10:95326623..95326652,+#_d7ef70998e117c30b280d3c550b22420p3@O3FAR1
3.29e-195FFCP PHASE2:Hg19::chr3:7961538..7961548,-#_d7ef70998e117c30b280d3c550b22420p@chr3:7961538..7961548, -
3.29e-195FFCP PHASE1:Hg19::chr11:109958698..109958703,-#_d7ef70998e117c30b280d3c550b22420p@chr11:109958698..109958703, -
3.29e-195FFCP PHASE1:Hg19::chr12:112587704..112587710,+#_d7ef70998e117c30b280d3c550b22420p@chr12:112587704..112587710, +
3.29e-195FFCP PHASE2:Hg19::chr2:242169538..242169541,-#_d7ef70998e117c30b280d3c550b22420p71@HDLBP
3.29e-195FFCP PHASE1:Hg19::chr1:229182571..229182583,-#_d7ef70998e117c30b280d3c550b22420p@chr1:229182571..229182583, -
3.29e-195FFCP PHASE1:Hg19::chr18:53545759..53545802,+#_d7ef70998e117c30b280d3c550b22420p@chr18:53545759..53545802, +
3.29e-195FFCP PHASE1:Hg19::chr2:71057873..71057874,-#_d7ef70998e117c30b280d3c550b22420p@chr2:71057873..71057874, -
3.29e-195FFCP PHASE2:Hg19::chr19:6063965..6063994,+#_d7ef70998e117c30b280d3c550b22420p@chr19:6063965..6063994, +
3.29e-195FFCP PHASE1:Hg19::chr2:135821386..135821432,+#_d7ef70998e117c30b280d3c550b22420p@chr2:135821386..135821432, +
3.29e-195FFCP PHASE1:Hg19::chr7:111726632..111726641,-#_d7ef70998e117c30b280d3c550b22420p@chr7:111726632..111726641, -
3.29e-195FFCP PHASE1:Hg19::chr6:33084930..33084937,+#_d7ef70998e117c30b280d3c550b22420p@chr6:33084930..33084937, +
3.29e-195FFCP PHASE2:Hg19::chr20:62482031..62482052,-#_d7ef70998e117c30b280d3c550b22420p@chr20:62482031..62482052, -
3.29e-195FFCP PHASE2:Hg19::chr9:8384123..8384141,-#_d7ef70998e117c30b280d3c550b22420p@chr9:8384123..8384141, -
3.29e-195FFCP PHASE2:Hg19::chr2:71057780..71057794,-#_d7ef70998e117c30b280d3c550b22420p@chr2:71057780..71057794, -
3.29e-195FFCP PHASE2:Hg19::chr18:53545728..53545733,+#_d7ef70998e117c30b280d3c550b22420p@chr18:53545728..53545733, +
3.29e-195FFCP PHASE2:Hg19::chr6:4337610..4337616,+#_d7ef70998e117c30b280d3c550b22420p@chr6:4337610..4337616, +
3.29e-195FFCP PHASE1:Hg19::chr18:46523734..46523740,+#_d7ef70998e117c30b280d3c550b22420p@chr18:46523734..46523740, +
3.29e-195FFCP PHASE2:Hg19::chr20:1762918..1762921,-#_d7ef70998e117c30b280d3c550b22420p@chr20:1762918..1762921, -
4.61e-131FFCP PHASE2:Hg19::chr7:55594397..55594400,+#_f74d077167c0d9bc81a935136da2d327p@chr7:55594397..55594400, +
4.61e-131FFCP PHASE2:Hg19::chr1:229182494..229182507,-#_f74d077167c0d9bc81a935136da2d327p@chr1:229182494..229182507, -
4.61e-131FFCP PHASE2:Hg19::chr8:39806514..39806522,+#_f74d077167c0d9bc81a935136da2d327p3@IDO2
4.61e-131FFCP PHASE2:Hg19::chr2:64587249..64587257,-#_f74d077167c0d9bc81a935136da2d327p@chr2:64587249..64587257, -
4.61e-131FFCP PHASE1:Hg19::chr19:35481583..35481590,-#_f74d077167c0d9bc81a935136da2d327p@chr19:35481583..35481590, -
4.61e-131FFCP PHASE2:Hg19::chr8:62629856..62629862,+#_f74d077167c0d9bc81a935136da2d327p@chr8:62629856..62629862, +
4.61e-131FFCP PHASE1:Hg19::chr2:216002151..216002158,+#_f74d077167c0d9bc81a935136da2d327p@chr2:216002151..216002158, +
4.61e-131FFCP PHASE2:Hg19::chr12:322653..322665,-#_f74d077167c0d9bc81a935136da2d327p8@SLC6A12
4.61e-131FFCP PHASE2:Hg19::chr2:235214861..235214870,+#_f74d077167c0d9bc81a935136da2d327p@chr2:235214861..235214870, +
4.61e-131FFCP PHASE2:Hg19::chr10:97592419..97592428,+#_f74d077167c0d9bc81a935136da2d327p@chr10:97592419..97592428, +
4.61e-131FFCP PHASE1:Hg19::chr1:229182494..229182507,-#_f74d077167c0d9bc81a935136da2d327p@chr1:229182494..229182507, -
4.61e-131FFCP PHASE2:Hg19::chr2:128408404..128408428,-#_f74d077167c0d9bc81a935136da2d327p34@LIMS2
4.61e-131FFCP PHASE2:Hg19::chr1:157926828..157926838,+#_f74d077167c0d9bc81a935136da2d327p@chr1:157926828..157926838, +
4.61e-131FFCP PHASE2:Hg19::chr9:8384168..8384183,-#_f74d077167c0d9bc81a935136da2d327p@chr9:8384168..8384183, -
4.61e-131FFCP PHASE2:Hg19::chr6:32729634..32729642,-#_f74d077167c0d9bc81a935136da2d327p2@M95729
4.61e-131FFCP PHASE2:Hg19::chr11:12228326..12228332,+#_f74d077167c0d9bc81a935136da2d327p@chr11:12228326..12228332, +
4.61e-131FFCP PHASE2:Hg19::chr11:109959243..109959256,+#_f74d077167c0d9bc81a935136da2d327p@chr11:109959243..109959256, +
4.61e-131FFCP PHASE1:Hg19::chr12:322653..322665,-#_f74d077167c0d9bc81a935136da2d327p8@SLC6A12
4.61e-131FFCP PHASE2:Hg19::chr19:6063658..6063670,-#_f74d077167c0d9bc81a935136da2d327p@chr19:6063658..6063670, -
4.61e-131FFCP PHASE1:Hg19::chr10:97592419..97592428,+#_f74d077167c0d9bc81a935136da2d327p@chr10:97592419..97592428, +
4.61e-131FFCP PHASE2:Hg19::chr2:216002151..216002158,+#_f74d077167c0d9bc81a935136da2d327p@chr2:216002151..216002158, +
4.61e-131FFCP PHASE1:Hg19::chr2:191756900..191756912,+#_f74d077167c0d9bc81a935136da2d327p@chr2:191756900..191756912, +
4.61e-131FFCP PHASE1:Hg19::chr1:157926828..157926838,+#_f74d077167c0d9bc81a935136da2d327p@chr1:157926828..157926838, +
4.61e-131FFCP PHASE1:Hg19::chr7:55594397..55594400,+#_f74d077167c0d9bc81a935136da2d327p@chr7:55594397..55594400, +
4.61e-131FFCP PHASE1:Hg19::chr8:39806514..39806522,+#_f74d077167c0d9bc81a935136da2d327p3@IDO2
4.61e-131FFCP PHASE1:Hg19::chr11:109959243..109959256,+#_f74d077167c0d9bc81a935136da2d327p@chr11:109959243..109959256, +
4.61e-131FFCP PHASE1:Hg19::chr2:64587249..64587257,-#_f74d077167c0d9bc81a935136da2d327p@chr2:64587249..64587257, -
4.61e-131FFCP PHASE1:Hg19::chr11:12228326..12228332,+#_f74d077167c0d9bc81a935136da2d327p@chr11:12228326..12228332, +
4.61e-131FFCP PHASE1:Hg19::chr19:6063658..6063670,-#_f74d077167c0d9bc81a935136da2d327p@chr19:6063658..6063670, -
4.61e-131FFCP PHASE1:Hg19::chr8:62629856..62629862,+#_f74d077167c0d9bc81a935136da2d327p@chr8:62629856..62629862, +
4.61e-131FFCP PHASE2:Hg19::chr19:35481583..35481590,-#_f74d077167c0d9bc81a935136da2d327p@chr19:35481583..35481590, -
4.61e-131FFCP PHASE1:Hg19::chr16:10953616..10953637,+#_f74d077167c0d9bc81a935136da2d327p@chr16:10953616..10953637, +