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MCL coexpression mm9:1045

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Phase1 CAGE Peaks

  Short description
Mm9::chr10:80392977..80392985,+ p4@Gadd45b
Mm9::chr15:61819234..61819308,+ p@chr15:61819234..61819308
+
Mm9::chr15:61819573..61819671,+ p@chr15:61819573..61819671
+
Mm9::chr15:61821037..61821049,+ p@chr15:61821037..61821049
+
Mm9::chr3:58218663..58218693,+ p@chr3:58218663..58218693
+
Mm9::chr3:58218700..58218716,+ p@chr3:58218700..58218716
+
Mm9::chr6:83392692..83392718,- p@chr6:83392692..83392718
-


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


GO IDGO nameFDR corrected p-value
GO:0043085positive regulation of catalytic activity0.00848527128717106
GO:0008633activation of pro-apoptotic gene products0.00848527128717106
GO:0050790regulation of catalytic activity0.00848527128717106
GO:0008634negative regulation of survival gene product activity0.00848527128717106
GO:0065009regulation of a molecular function0.00848527128717106
GO:0001783B cell apoptosis0.00848527128717106
GO:0051726regulation of cell cycle0.00848527128717106
GO:0042474middle ear morphogenesis0.00941046571901774
GO:0006309DNA fragmentation during apoptosis0.00941046571901774
GO:0050910detection of mechanical stimulus during sensory perception of sound0.00941046571901774
GO:0006921cell structure disassembly during apoptosis0.00941046571901774
GO:0022402cell cycle process0.00941046571901774
GO:0030262apoptotic nuclear changes0.00941046571901774
GO:0006915apoptosis0.00941046571901774
GO:0012501programmed cell death0.00941046571901774
GO:0001836release of cytochrome c from mitochondria0.00941046571901774
GO:0045884regulation of survival gene product activity0.00941046571901774
GO:0000186activation of MAPKK activity0.00941046571901774
GO:0050974detection of mechanical stimulus during sensory perception0.00941046571901774
GO:0008219cell death0.00941046571901774
GO:0016265death0.00941046571901774
GO:0050982detection of mechanical stimulus0.0098288130961369
GO:0006308DNA catabolic process0.0098288130961369
GO:0007049cell cycle0.0098288130961369
GO:0043279response to alkaloid0.0116010135295285
GO:0009612response to mechanical stimulus0.0116010135295285
GO:0008637apoptotic mitochondrial changes0.0124849380356378
GO:0006919caspase activation0.0126723341347702
GO:0043280positive regulation of caspase activity0.012846772829689
GO:0022411cellular component disassembly0.0130095498608156
GO:0048705skeletal morphogenesis0.0131617937762588
GO:0051345positive regulation of hydrolase activity0.0133044920556141
GO:0006997nuclear organization and biogenesis0.0138618984365038
GO:0007242intracellular signaling cascade0.0138618984365038
GO:0010033response to organic substance0.0143808690559699
GO:0032147activation of protein kinase activity0.0143808690559699
GO:0008629induction of apoptosis by intracellular signals0.0143808690559699
GO:0043281regulation of caspase activity0.0144687759505001
GO:0048468cell development0.0152654088873376
GO:0006469negative regulation of protein kinase activity0.0153144448360408
GO:0033673negative regulation of kinase activity0.0153144448360408
GO:0005819spindle0.0153144448360408
GO:0051348negative regulation of transferase activity0.0153144448360408
GO:0016604nuclear body0.0153144448360408
GO:0009582detection of abiotic stimulus0.0173356064459318
GO:0043086negative regulation of catalytic activity0.0180964821540238
GO:0009581detection of external stimulus0.0180964821540238
GO:0008632apoptotic program0.0180964821540238
GO:0050906detection of stimulus during sensory perception0.0198945647774472
GO:0042471ear morphogenesis0.0212661807720997
GO:0016485protein processing0.0228294942868084
GO:0007005mitochondrion organization and biogenesis0.0228294942868084
GO:0051606detection of stimulus0.0230661023719913
GO:0043583ear development0.0242389304980314
GO:0048869cellular developmental process0.0242389304980314
GO:0030154cell differentiation0.0242389304980314
GO:0006916anti-apoptosis0.0242389304980314
GO:0045860positive regulation of protein kinase activity0.0253445269421714
GO:0033674positive regulation of kinase activity0.026266444974434
GO:0051347positive regulation of transferase activity0.026266444974434
GO:0007605sensory perception of sound0.026558655997863
GO:0009314response to radiation0.026558655997863
GO:0050954sensory perception of mechanical stimulus0.0272582711886683
GO:0051336regulation of hydrolase activity0.0301418900256973
GO:0000165MAPKKK cascade0.0323920340714532
GO:0007275multicellular organismal development0.0330693654384248
GO:0045859regulation of protein kinase activity0.0330693654384248
GO:0006917induction of apoptosis0.0330693654384248
GO:0012502induction of programmed cell death0.0330693654384248
GO:0043549regulation of kinase activity0.0333522635888105
GO:0051338regulation of transferase activity0.0336270694995324
GO:0043066negative regulation of apoptosis0.0365659272351112
GO:0043069negative regulation of programmed cell death0.0365659272351112
GO:0043065positive regulation of apoptosis0.0388756715682953
GO:0043068positive regulation of programmed cell death0.0388756715682953
GO:0009628response to abiotic stimulus0.0390584548816205
GO:0008284positive regulation of cell proliferation0.0403780821077872
GO:0001501skeletal development0.0407618443253016
GO:0007423sensory organ development0.0415805314464115
GO:0048598embryonic morphogenesis0.0443538016122502
GO:0032502developmental process0.04712373003694
GO:0007243protein kinase cascade0.04712373003694
GO:0043285biopolymer catabolic process0.0490907465633064



Relative expression of the co-expression cluster over median
Analyst:





Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset






TFBS overrepresentationSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.339775
MA0004.10.481116
MA0006.10.311391
MA0007.10.465969
MA0009.10.92425
MA0014.10.222567
MA0017.10.337808
MA0019.10.740036
MA0024.10.880057
MA0025.11.15921
MA0027.12.57545
MA0028.10.321735
MA0029.10.858105
MA0030.10.864739
MA0031.10.828781
MA0038.10.62758
MA0040.10.936879
MA0041.10.404721
MA0042.10.391504
MA0043.11.02178
MA0046.10.960497
MA0048.10.801219
MA0050.10.520357
MA0051.10.636645
MA0052.10.945011
MA0055.15.04439
MA0056.10
MA0057.10.756125
MA0058.10.384683
MA0059.10.397033
MA0060.10.232592
MA0061.10.724575
MA0063.10
MA0066.10.616444
MA0067.11.27078
MA0068.11.83304
MA0069.10.945354
MA0070.10.93557
MA0071.10.519509
MA0072.10.927016
MA0073.10.152496
MA0074.10.580087
MA0076.10.356883
MA0077.10.905143
MA0078.10.670113
MA0081.10.420276
MA0083.11.02098
MA0084.11.59945
MA0087.10.977537
MA0088.11.00582
MA0089.10
MA0090.10.446539
MA0091.10.494398
MA0092.10.446857
MA0093.10.329976
MA0095.10
MA0098.10
MA0100.10.568369
MA0101.10.406019
MA0103.10.348572
MA0105.10.488671
MA0106.10.677988
MA0107.10.342432
MA0108.20.763162
MA0109.10
MA0111.10.460823
MA0113.10.649407
MA0114.10.259463
MA0115.11.0246
MA0116.10.836994
MA0117.10.992087
MA0119.10.40661
MA0122.11.01209
MA0124.11.21735
MA0125.11.14291
MA0130.10
MA0131.10.735438
MA0132.10
MA0133.10
MA0135.11.05845
MA0136.10.600242
MA0139.10.202522
MA0140.10.568252
MA0141.10.368264
MA0142.10.814115
MA0143.10.665982
MA0144.10.262477
MA0145.10.304732
MA0146.10.108739
MA0147.10.274511
MA0148.10.49752
MA0149.10.411562
MA0062.20.167299
MA0035.20.573016
MA0039.21.06357
MA0138.20.727395
MA0002.20.205289
MA0137.20.365364
MA0104.20.218974
MA0047.20.626803
MA0112.20.0910939
MA0065.20.633155
MA0150.10.465855
MA0151.10
MA0152.10.626912
MA0153.11.07519
MA0154.11.87278
MA0155.10.102995
MA0156.10.356017
MA0157.10.781683
MA0158.10
MA0159.10.284457
MA0160.10.50056
MA0161.10
MA0162.11.26636
MA0163.13.21163
MA0164.10.600609
MA0080.20.343316
MA0018.21.48306
MA0099.20.721008
MA0079.20.0369305
MA0102.21.65195
MA0258.10.246285
MA0259.10.26402
MA0442.10