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MCL coexpression mm9:133

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Phase1 CAGE Peaks

  Short description
Mm9::chr10:14437997..14438034,- p1@Gje1
Mm9::chr10:19925162..19925172,+ p@chr10:19925162..19925172
+
Mm9::chr10:62562530..62562540,+ p1@Atoh7
Mm9::chr11:120494497..120494508,+ p@chr11:120494497..120494508
+
Mm9::chr12:74046619..74046630,+ p@chr12:74046619..74046630
+
Mm9::chr12:74046665..74046675,+ p@chr12:74046665..74046675
+
Mm9::chr12:74046677..74046684,+ p@chr12:74046677..74046684
+
Mm9::chr12:74046687..74046697,+ p@chr12:74046687..74046697
+
Mm9::chr12:74046750..74046761,+ p@chr12:74046750..74046761
+
Mm9::chr12:74046774..74046787,+ p@chr12:74046774..74046787
+
Mm9::chr12:85910771..85910785,+ p1@Vsx2
Mm9::chr12:86865603..86865614,+ p@chr12:86865603..86865614
+
Mm9::chr13:31991492..31991501,+ p@chr13:31991492..31991501
+
Mm9::chr13:81709652..81709670,- p2@Gpr98
Mm9::chr14:18814020..18814023,+ p3@Thrb
Mm9::chr14:61103994..61104005,+ p@chr14:61103994..61104005
+
Mm9::chr14:61104008..61104026,+ p@chr14:61104008..61104026
+
Mm9::chr14:61108681..61108683,+ p@chr14:61108681..61108683
+
Mm9::chr15:30564498..30564511,+ p@chr15:30564498..30564511
+
Mm9::chr17:18368516..18368523,- p@chr17:18368516..18368523
-
Mm9::chr17:24751444..24751455,- p@chr17:24751444..24751455
-
Mm9::chr17:24751458..24751473,- p@chr17:24751458..24751473
-
Mm9::chr17:35164482..35164492,+ p@chr17:35164482..35164492
+
Mm9::chr17:78707813..78707820,+ +
p@chr17:78707813..78707820
Mm9::chr17:86014340..86014350,- p3@ENSMUST00000162311
Mm9::chr17:86014476..86014492,- p1@ENSMUST00000162311
Mm9::chr17:86014504..86014516,- p2@ENSMUST00000162311
Mm9::chr18:66095599..66095632,- p@chr18:66095599..66095632
-
Mm9::chr18:66098673..66098684,- p2@Rax
Mm9::chr18:66098702..66098742,- p1@Rax
Mm9::chr18:66098752..66098757,- p3@Rax
Mm9::chr18:66182144..66182159,- p2@Lman1
Mm9::chr18:66182236..66182254,- p3@Lman1
Mm9::chr18:84888878..84888899,+ p@chr18:84888878..84888899
+
Mm9::chr18:84890097..84890110,- p2@ENSMUST00000162318
Mm9::chr18:84890165..84890175,- p1@ENSMUST00000162318
Mm9::chr19:46222859..46222876,- p1@Pitx3
Mm9::chr1:152472420..152472431,+ p1@uc007cyk.1
Mm9::chr1:51936265..51936290,- p@chr1:51936265..51936290
-
Mm9::chr1:92672349..92672354,- p@chr1:92672349..92672354
-
Mm9::chr2:105500930..105500942,+ p@chr2:105500930..105500942
+
Mm9::chr2:105500957..105500969,+ p@chr2:105500957..105500969
+
Mm9::chr2:120302586..120302587,+ p8@Capn3
Mm9::chr2:120302647..120302660,+ p2@Capn3
Mm9::chr2:173232557..173232568,+ p@chr2:173232557..173232568
+
Mm9::chr2:180121458..180121468,- p2@uc008oiz.1
Mm9::chr2:180121498..180121502,- p3@uc008oiz.1
Mm9::chr2:68253915..68253921,- p@chr2:68253915..68253921
-
Mm9::chr2:90608579..90608583,+ p10@Fnbp4
Mm9::chr2:90827760..90827769,+ p6@Celf1
Mm9::chr3:121876676..121876690,+ p@chr3:121876676..121876690
+
Mm9::chr3:17685526..17685557,- p@chr3:17685526..17685557
-
Mm9::chr3:17685568..17685584,- p@chr3:17685568..17685584
-
Mm9::chr3:26229959..26229976,- p@chr3:26229959..26229976
-
Mm9::chr3:86355053..86355062,- p@chr3:86355053..86355062
-
Mm9::chr3:96729842..96729864,- p1@Gja8
Mm9::chr3:96729979..96729990,- p2@Gja8
Mm9::chr4:114598669..114598674,- p1@Foxe3
Mm9::chr4:140954146..140954156,- p5@Clcnka
Mm9::chr5:103270071..103270076,+ p@chr5:103270071..103270076
+
Mm9::chr5:112688326..112688337,+ p@chr5:112688326..112688337
+
Mm9::chr5:112688342..112688357,+ p@chr5:112688342..112688357
+
Mm9::chr5:112690761..112690766,+ p@chr5:112690761..112690766
+
Mm9::chr5:113505559..113505563,- p@chr5:113505559..113505563
-
Mm9::chr5:113506006..113506025,- p@chr5:113506006..113506025
-
Mm9::chr5:113506223..113506243,- p@chr5:113506223..113506243
-
Mm9::chr5:114723781..114723795,- p1@Foxn4
Mm9::chr5:114723842..114723847,- p5@Foxn4
Mm9::chr5:114724042..114724090,- p2@Foxn4
Mm9::chr5:24263661..24263674,- p1@Crygn
Mm9::chr5:35731493..35731531,+ p1@Hmx1
Mm9::chr5:35731576..35731581,+ p4@Hmx1
Mm9::chr6:25639495..25639506,- p11@Gpr37
Mm9::chr6:54629340..54629346,+ p@chr6:54629340..54629346
+
Mm9::chr7:129041851..129041873,+ p@chr7:129041851..129041873
+
Mm9::chr7:150755077..150755109,- p4@Cars
Mm9::chr7:152082428..152082444,+ p1@Fgf15
Mm9::chr7:152127385..152127398,- p@chr7:152127385..152127398
-
Mm9::chr7:152127432..152127449,- p@chr7:152127432..152127449
-
Mm9::chr8:113239018..113239029,+ p@chr8:113239018..113239029
+
Mm9::chr8:77582172..77582183,+ p@chr8:77582172..77582183
+
Mm9::chr8:77582194..77582219,+ p@chr8:77582194..77582219
+
Mm9::chr8:77582242..77582256,+ p@chr8:77582242..77582256
+
Mm9::chr8:77584221..77584232,+ p3@Tom1
Mm9::chr8:80960539..80960548,- p1@Pou4f2
Mm9::chr9:103382696..103382703,- p7@Bfsp2
Mm9::chr9:89697580..89697585,- p1@Mir184
Mm9::chrX:104872176..104872196,+ p@chrX:104872176..104872196
+


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


GO IDGO nameFDR corrected p-value
GO:0048731system development3.17060640578933e-07
GO:0007275multicellular organismal development4.02825301259622e-07
GO:0048856anatomical structure development7.97422795057435e-07
GO:0032502developmental process9.12510268051575e-06
GO:0032501multicellular organismal process1.08255785665892e-05
GO:0048513organ development1.17311696845874e-05
GO:0007399nervous system development3.11009248615317e-05
GO:0007423sensory organ development0.000159224236750079
GO:0007605sensory perception of sound0.000233166117341199
GO:0050954sensory perception of mechanical stimulus0.000259137051900052
GO:0043565sequence-specific DNA binding0.000442967931610447
GO:0003700transcription factor activity0.0014541529760685
GO:0060041retina development in camera-type eye0.00176540729959801
GO:0043010camera-type eye development0.00298502399539803
GO:0048869cellular developmental process0.00298502399539803
GO:0030154cell differentiation0.00298502399539803
GO:0022829wide pore channel activity0.00509830734741156
GO:0005243gap junction channel activity0.00509830734741156
GO:0005922connexon complex0.00509830734741156
GO:0001654eye development0.00617227078149919
GO:0048468cell development0.00617227078149919
GO:0030182neuron differentiation0.00702146208390581
GO:0005921gap junction0.00852112694554378
GO:0005212structural constituent of eye lens0.00852112694554378
GO:0048699generation of neurons0.0100366314732522
GO:0022008neurogenesis0.0125660305513375
GO:0003676nucleic acid binding0.014097615774352
GO:0016070RNA metabolic process0.014097615774352
GO:0065007biological regulation0.0143830397897842
GO:0006355regulation of transcription, DNA-dependent0.0154715056464117
GO:0006351transcription, DNA-dependent0.0156396531110116
GO:0032774RNA biosynthetic process0.0156396531110116
GO:0060040retinal bipolar neuron differentiation0.0156396531110116
GO:0014067negative regulation of phosphoinositide 3-kinase cascade0.0156396531110116
GO:0003677DNA binding0.0158314397610302
GO:0045449regulation of transcription0.0165934957700897
GO:0014704intercalated disc0.0165934957700897
GO:0019219regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0182292920822626
GO:0005667transcription factor complex0.0182292920822626
GO:0006350transcription0.0188991732135179
GO:0009653anatomical structure morphogenesis0.0210665078456802
GO:0010468regulation of gene expression0.0221428222969416
GO:0009649entrainment of circadian clock0.0221428222969416
GO:0043547positive regulation of GTPase activity0.0221428222969416
GO:0014066regulation of phosphoinositide 3-kinase cascade0.0221428222969416
GO:0006423cysteinyl-tRNA aminoacylation0.0221428222969416
GO:0004817cysteine-tRNA ligase activity0.0221428222969416
GO:0060042retina morphogenesis in camera-type eye0.0221428222969416
GO:0031323regulation of cellular metabolic process0.0244617526616222
GO:0050794regulation of cellular process0.0244617526616222
GO:0009887organ morphogenesis0.0265603447616523
GO:0010467gene expression0.027415445658086
GO:0019222regulation of metabolic process0.0274710781192674
GO:0044451nucleoplasm part0.0274710781192674
GO:0014065phosphoinositide 3-kinase cascade0.0274710781192674
GO:0048676axon extension involved in development0.0274710781192674
GO:0042473outer ear morphogenesis0.0274710781192674
GO:0004887thyroid hormone receptor activity0.0274710781192674
GO:0043583ear development0.0292549535875154
GO:0005654nucleoplasm0.0313707201051854
GO:0051898negative regulation of protein kinase B signaling cascade0.0342443568458092
GO:0005793ER-Golgi intermediate compartment0.0342443568458092
GO:0051896regulation of protein kinase B signaling cascade0.0408052151797968
GO:0046626regulation of insulin receptor signaling pathway0.0408052151797968
GO:0043209myelin sheath0.0408052151797968
GO:0050789regulation of biological process0.0416096075125384
GO:0006139nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0417836073135098
GO:0045165cell fate commitment0.0432855424115458
GO:0042474middle ear morphogenesis0.0460998529379166
GO:0031981nuclear lumen0.0493290610772881
GO:0007601visual perception0.0498269178099654
GO:0050953sensory perception of light stimulus0.0499982868278047



Relative expression of the co-expression cluster over median
Analyst:





Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset


uberon_data


Uber Anatomy
Ontology termp-valuen
eye5.61e-389
camera-type eye5.61e-389
simple eye5.61e-389
immature eye5.61e-389
ocular region5.61e-389
visual system5.61e-389
face5.61e-389
optic cup5.61e-389
optic vesicle5.61e-389
eye primordium5.61e-389
subdivision of head6.25e-3111
sense organ2.76e-2812
sensory system2.76e-2812
entire sense organ system2.76e-2812
head4.78e-2613
ectodermal placode4.78e-2613
craniocervical region8.15e-0936
pre-chordal neural plate7.42e-0849
anterior region of body3.22e-0743


TFBS overrepresentationSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.12.52929
MA0004.10.246821
MA0006.10.0734747
MA0007.10.0478182
MA0009.10.32515
MA0014.10.0519294
MA0017.10.0226026
MA0019.10.144022
MA0024.10.0804853
MA0025.10.225742
MA0027.11.48273
MA0028.10.00115733
MA0029.10.0722024
MA0030.10.0746529
MA0031.10.0619169
MA0038.10.0701547
MA0040.10.104202
MA0041.10.221769
MA0042.10.0499362
MA0043.10.145499
MA0046.10.115002
MA0048.10.135775
MA0050.10.0818966
MA0051.10.624557
MA0052.10.349675
MA0055.10.389529
MA0056.10
MA0057.10.829526
MA0058.10.299059
MA0059.10.11381
MA0060.10.00631716
MA0061.10.876373
MA0063.10
MA0066.11.19506
MA0067.10.301247
MA0068.10.0276468
MA0069.10.350086
MA0070.10.33843
MA0071.10.763745
MA0072.10.328374
MA0073.13.73596
MA0074.10.272587
MA0076.10.00248208
MA0077.12.7697
MA0078.11.90623
MA0081.10.255167
MA0083.10.874477
MA0084.10.562229
MA0087.10.779274
MA0088.10.289428
MA0089.10
MA0090.10.0939368
MA0091.10.44548
MA0092.10.317657
MA0093.10.270032
MA0095.10
MA0098.10
MA0100.10.252958
MA0101.10.359812
MA0103.10.0624834
MA0105.10.52003
MA0106.14.19819
MA0107.10.0572829
MA0108.20.663057
MA0109.10
MA0111.10.0451719
MA0113.10.661959
MA0114.10.0293833
MA0115.10.146985
MA0116.11.31366
MA0117.10.407968
MA0119.10.00608287
MA0122.10.140445
MA0124.10.264049
MA0125.10.215442
MA0130.10
MA0131.10.0351382
MA0132.10
MA0133.10
MA0135.10.165378
MA0136.10.0566883
MA0139.10.729131
MA0140.10.121451
MA0141.10.561159
MA0142.10.457557
MA0143.10.437405
MA0144.10.00472046
MA0145.10.214749
MA0146.10.757519
MA0147.10.213222
MA0148.10.150209
MA0149.10.000913137
MA0062.20.000157215
MA0035.20.125878
MA0039.20.0103803
MA0138.20.0332509
MA0002.20.0644266
MA0137.20.0121743
MA0104.20.416234
MA0047.20.0149432
MA0112.21.63383
MA0065.20.0532747
MA0150.11.37239
MA0151.10
MA0152.10.596614
MA0153.10.174838
MA0154.10.249408
MA0155.12.22476
MA0156.10.0691745
MA0157.10.0472741
MA0158.10
MA0159.11.31188
MA0160.10.68783
MA0161.10
MA0162.10.159609
MA0163.11.54248
MA0164.10.308679
MA0080.20.0247642
MA0018.20.0615045
MA0099.20.306082
MA0079.21.36607
MA0102.20.607761
MA0258.10.75214
MA0259.10.184363
MA0442.10