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MCL coexpression mm9:1487

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Phase1 CAGE Peaks

 Short description
Mm9::chrM:10603..10606,+p@chrM:10603..10606
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Mm9::chrM:7005..7022,+p1@COX2
Mm9::chrM:7759..7794,+p1@ATP8
Mm9::chrM:9452..9468,+p1@ND3
Mm9::chrM:9870..9885,+p1@ND4L
Mm9::chrX:60568425..60568442,+p@chrX:60568425..60568442
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0004666prostaglandin-endoperoxide synthase activity0.00864828482206447
GO:0046457prostanoid biosynthetic process0.00864828482206447
GO:0001516prostaglandin biosynthetic process0.00864828482206447
GO:0042640anagen0.00864828482206447
GO:0006693prostaglandin metabolic process0.00864828482206447
GO:0006692prostanoid metabolic process0.00864828482206447
GO:0048820hair follicle maturation0.00864828482206447
GO:0030216keratinocyte differentiation0.0110291891455478
GO:0046456icosanoid biosynthetic process0.0110291891455478
GO:0006690icosanoid metabolic process0.0110291891455478
GO:0004601peroxidase activity0.0110291891455478
GO:0016684oxidoreductase activity, acting on peroxide as acceptor0.0110291891455478
GO:0008217regulation of blood pressure0.0110291891455478
GO:0022404molting cycle process0.0110291891455478
GO:0001942hair follicle development0.0110291891455478
GO:0022405hair cycle process0.0110291891455478
GO:0042633hair cycle0.0110291891455478
GO:0042303molting cycle0.0110291891455478
GO:0006979response to oxidative stress0.0110291891455478
GO:0048589developmental growth0.0111762450008218
GO:0051213dioxygenase activity0.0121480923921976
GO:0016702oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen0.0121480923921976
GO:0016701oxidoreductase activity, acting on single donors with incorporation of molecular oxygen0.0121480923921976
GO:0006633fatty acid biosynthetic process0.0130747737990383
GO:0016053organic acid biosynthetic process0.0130747737990383
GO:0046394carboxylic acid biosynthetic process0.0130747737990383
GO:0021700developmental maturation0.0149016600010957
GO:0008015blood circulation0.0149016600010957
GO:0003013circulatory system process0.0149016600010957
GO:0008544epidermis development0.0149016600010957
GO:0007398ectoderm development0.0151720530253091
GO:0020037heme binding0.0156636767056972
GO:0046906tetrapyrrole binding0.0156636767056972
GO:0016705oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen0.0171204733468471
GO:0005792microsome0.0201373783798591
GO:0042598vesicular fraction0.0201373783798591
GO:0006631fatty acid metabolic process0.0201373783798591
GO:0032787monocarboxylic acid metabolic process0.0261024143111298
GO:0008610lipid biosynthetic process0.0281794211559182
GO:0009888tissue development0.0327138004711554
GO:0005506iron ion binding0.0333924393317236
GO:0006118electron transport0.0348148901811313
GO:0006091generation of precursor metabolites and energy0.0442934516020941
GO:0042221response to chemical stimulus0.0443879234075191
GO:0005624membrane fraction0.0443879234075191
GO:0019752carboxylic acid metabolic process0.0443879234075191
GO:0006082organic acid metabolic process0.0443879234075191
GO:0000267cell fraction0.0480882650545563
GO:0044255cellular lipid metabolic process0.0480882650545563



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
mucosa7.46e-0815
connective tissue6.06e-0746


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.00973143
MA0004.10.536396
MA0006.10.359699
MA0007.10.52077
MA0009.10.987341
MA0014.10.0315641
MA0017.10.387481
MA0019.10.800946
MA0024.10.942716
MA0025.11.22395
MA0027.12.64231
MA0028.10.370592
MA0029.10.920529
MA0030.10.927235
MA0031.10.890871
MA0038.10.686534
MA0040.11.00009
MA0041.10.457338
MA0042.10.443591
MA0043.11.08567
MA0046.11.02391
MA0048.10.161427
MA0050.10.57678
MA0051.10.695779
MA0052.11.00829
MA0055.10.0585191
MA0056.10
MA0057.10.149949
MA0058.10.436487
MA0059.10.449345
MA0060.10.275911
MA0061.10.307097
MA0063.10
MA0066.10.675169
MA0067.11.33603
MA0068.10.153907
MA0069.11.00864
MA0070.10.998765
MA0071.10.575909
MA0072.10.990133
MA0073.10.000157319
MA0074.10.638014
MA0076.10.407465
MA0077.10.968053
MA0078.10.729877
MA0081.10.473489
MA0083.11.08487
MA0084.11.66561
MA0087.11.04109
MA0088.10.111145
MA0089.10
MA0090.10.500693
MA0091.10.55008
MA0092.10.501022
MA0093.10.379257
MA0095.10
MA0098.10
MA0100.10.626021
MA0101.10.458688
MA0103.10.398766
MA0105.10.199622
MA0106.10.737893
MA0107.10.392331
MA0108.20.824407
MA0109.10
MA0111.10.515457
MA0113.10.708789
MA0114.10.304661
MA0115.11.08851
MA0116.10.359483
MA0117.11.05576
MA0119.10.459301
MA0122.11.07591
MA0124.11.28237
MA0125.11.20757
MA0130.10
MA0131.10.796279
MA0132.10
MA0133.10
MA0135.11.1226
MA0136.10.658622
MA0139.10.243463
MA0140.10.625902
MA0141.10.419361
MA0142.10.876028
MA0143.10.725672
MA0144.10.307873
MA0145.10.119202
MA0146.10.0392287
MA0147.10.320675
MA0148.10.553294
MA0149.10.464445
MA0062.20.204999
MA0035.20.630778
MA0039.20.00481054
MA0138.20.788113
MA0002.20.246463
MA0137.20.416331
MA0104.20.261255
MA0047.20.685741
MA0112.20.119197
MA0065.20.119561
MA0150.10.520653
MA0151.10
MA0152.10.685852
MA0153.11.13945
MA0154.10.159217
MA0155.10.132921
MA0156.10.406559
MA0157.10.843181
MA0158.10
MA0159.10.331229
MA0160.10.556423
MA0161.10
MA0162.10.0465447
MA0163.10.0423021
MA0164.10.658997
MA0080.20.393257
MA0018.20.669032
MA0099.20.781628
MA0079.24.33609e-06
MA0102.21.7182
MA0258.10.290587
MA0259.10.309517
MA0442.10