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UBERON:0002120

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Name:pronephros
Namespace:FANTOM
Definition:"In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensible for larval life[GO]." [GO:0048793, Wikipedia:Pronephros]
Xrefs:
links:

AAO:0011089
BTO:0001541
EFO:0000927
EHDAA2:0001570
EHDAA:1017
EMAPA:16579
FMA:72170
MAT:0000117
MIAA:0000117
ncithesaurus:Pronephros
SCTID:308804007
TAO:0000151
VHOG:0000037
XAO:0002000

ZFA:0000151
Synonyms: "archinephron" RELATED [BTO:0001541]
"embryonic kidney" RELATED [BTO:0001541]
"pronephric kidney" EXACT [XAO:0002000]
"pronephron" RELATED [BTO:0001541]
Comments:Once the more complex mesonephros forms the pronephros undergoes apoptosis in amphibians. In fishes the nephron degenerates but the organ remains and becomes a component of the immune system[Wikipedia:Pronephros]. // TODO - check developmental relationships. Note that we previously include the ZFA/XAO terms under the more specific 'pronephric kidney', but these are now merged. TODO GCI: relationship: capable_of GO:0030104
Alt_id: UBERON:0005794
UBERON:FMA_72170-MIAA_0000117-XAO_0002000-ZFA_0000151
Subset: organ_slim
uberon_slim

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:UBERON:0002113(kidney),UBERON:0004120(mesoderm-derived structure),UBERON:0005423(developing anatomical structure)
develops_from:UBERON:0005095(kidney rudiment),UBERON:0005721(pronephric mesoderm),UBERON:0005754(rostral part of nephrogenic cord)
part_of:UBERON:0003887(intraembryonic coelom)



Children

develops from:UBERON:0000080 (mesonephros)
part of:UBERON:0003060 (pronephric duct)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology




Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0002120 (pronephros), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data


P-valueFFCPShort description
2.83e-65FFCP PHASE2:Mm9::chr18:44264202..44264213,+#_dfc3d7f2f7d40a4190c9d022e331fe17p4@Spink12
2.83e-65FFCP PHASE1:Mm9::chr18:44264202..44264213,+#_dfc3d7f2f7d40a4190c9d022e331fe17p4@Spink12
2.83e-65FFCP PHASE2:Mm9::chr14:63665679..63665688,+#_dfc3d7f2f7d40a4190c9d022e331fe17p4@Defb42
2.83e-65FFCP PHASE1:Mm9::chr10:127470655..127470664,+#_dfc3d7f2f7d40a4190c9d022e331fe17p@chr10:127470655..127470664, +
2.83e-65FFCP PHASE2:Mm9::chr14:63585028..63585037,-#_dfc3d7f2f7d40a4190c9d022e331fe17p@chr14:63585028..63585037, -
2.83e-65FFCP PHASE1:Mm9::chr14:63585028..63585037,-#_dfc3d7f2f7d40a4190c9d022e331fe17p@chr14:63585028..63585037, -
2.83e-65FFCP PHASE1:Mm9::chr14:63665679..63665688,+#_dfc3d7f2f7d40a4190c9d022e331fe17p4@Defb42
2.83e-65FFCP PHASE2:Mm9::chr10:127470655..127470664,+#_dfc3d7f2f7d40a4190c9d022e331fe17p@chr10:127470655..127470664, +
3.99e-50FFCP PHASE2:Mm9::chr2:152388713..152388729,+#_af7b1b4569a348edf7a14b3894a630b9p@chr2:152388713..152388729, +
3.99e-50FFCP PHASE1:Mm9::chr2:152388713..152388729,+#_af7b1b4569a348edf7a14b3894a630b9p@chr2:152388713..152388729, +
5.6e-50FFCP PHASE2:Hg19::chr2:120409486..120409492,+#_e8dbb8ce83e3899a975c53ac0cdc786ap@chr2:120409486..120409492, +
5.6e-50FFCP PHASE1:Hg19::chr2:120409486..120409492,+#_e8dbb8ce83e3899a975c53ac0cdc786ap@chr2:120409486..120409492, +
1.6e-49FFCP PHASE2:Mm9::chr11:105797641..105797656,-#_322454c4f87acb7a8bb5c7fee7d231ddp4@Cyb561
1.6e-49FFCP PHASE2:Mm9::chr14:63585020..63585025,-#_322454c4f87acb7a8bb5c7fee7d231ddp@chr14:63585020..63585025, -
1.6e-49FFCP PHASE1:Mm9::chr14:63585020..63585025,-#_322454c4f87acb7a8bb5c7fee7d231ddp@chr14:63585020..63585025, -
1.6e-49FFCP PHASE1:Mm9::chr11:105797641..105797656,-#_322454c4f87acb7a8bb5c7fee7d231ddp4@Cyb561
1.6e-49FFCP PHASE2:Mm9::chr14:63585048..63585062,-#_322454c4f87acb7a8bb5c7fee7d231ddp@chr14:63585048..63585062, -
1.6e-49FFCP PHASE2:Mm9::chr11:76361451..76361499,+#_322454c4f87acb7a8bb5c7fee7d231ddp@chr11:76361451..76361499, +
1.6e-49FFCP PHASE2:Mm9::chr9:35597686..35597691,-#_322454c4f87acb7a8bb5c7fee7d231ddp2@D730048I06Rik, p2@Gm17727
1.6e-49FFCP PHASE1:Mm9::chr9:35597686..35597691,-#_322454c4f87acb7a8bb5c7fee7d231ddp2@D730048I06Rik, p2@Gm17727
1.6e-49FFCP PHASE1:Mm9::chr14:63585048..63585062,-#_322454c4f87acb7a8bb5c7fee7d231ddp@chr14:63585048..63585062, -
1.6e-49FFCP PHASE1:Mm9::chr11:76361451..76361499,+#_322454c4f87acb7a8bb5c7fee7d231ddp@chr11:76361451..76361499, +
2.33e-49FFCP PHASE1:Mm9::chr14:51734043..51734054,+#_9b36385b482b36b725c8708169c94498p2@Eddm3b
2.33e-49FFCP PHASE2:Mm9::chr14:63627556..63627564,-#_9b36385b482b36b725c8708169c94498p@chr14:63627556..63627564, -
2.33e-49FFCP PHASE1:Mm9::chr9:26611246..26611253,-#_9b36385b482b36b725c8708169c94498p@chr9:26611246..26611253, -
2.33e-49FFCP PHASE1:Mm9::chr14:63627556..63627564,-#_9b36385b482b36b725c8708169c94498p@chr14:63627556..63627564, -
2.33e-49FFCP PHASE2:Mm9::chr9:26611246..26611253,-#_9b36385b482b36b725c8708169c94498p@chr9:26611246..26611253, -
2.33e-49FFCP PHASE2:Mm9::chr9:26732045..26732085,+#_9b36385b482b36b725c8708169c94498p@chr9:26732045..26732085, +
2.33e-49FFCP PHASE2:Mm9::chr14:51734043..51734054,+#_9b36385b482b36b725c8708169c94498p2@Eddm3b
2.33e-49FFCP PHASE1:Mm9::chr9:26732045..26732085,+#_9b36385b482b36b725c8708169c94498p@chr9:26732045..26732085, +
3.4e-49FFCP PHASE2:Mm9::chr2:69981027..69981032,+#_273d5d205d9097d342700cc2315da66fp@chr2:69981027..69981032, +
3.4e-49FFCP PHASE1:Mm9::chr2:69981027..69981032,+#_273d5d205d9097d342700cc2315da66fp@chr2:69981027..69981032, +
9.75e-45FFCP PHASE1:Hg19::chr14:68644730..68644737,+#_b3a253cd914072d2cfaeec44686052b5p@chr14:68644730..68644737, +
9.75e-45FFCP PHASE2:Hg19::chr1:172416185..172416189,-#_b3a253cd914072d2cfaeec44686052b5p@chr1:172416185..172416189, -
9.75e-45FFCP PHASE1:Hg19::chr10:102505655..102505689,+#_b3a253cd914072d2cfaeec44686052b5p10@PAX2
9.75e-45FFCP PHASE2:Hg19::chr14:68644730..68644737,+#_b3a253cd914072d2cfaeec44686052b5p@chr14:68644730..68644737, +
9.75e-45FFCP PHASE1:Hg19::chr1:172416185..172416189,-#_b3a253cd914072d2cfaeec44686052b5p@chr1:172416185..172416189, -
9.75e-45FFCP PHASE2:Hg19::chr10:102505655..102505689,+#_b3a253cd914072d2cfaeec44686052b5p10@PAX2
4.54e-44FFCP PHASE2:Mm9::chr1:168436322..168436326,-#_e3a90d78abdf29a422505aa2b2f1e632p@chr1:168436322..168436326, -
4.54e-44FFCP PHASE2:Mm9::chr2:152290340..152290344,-#_e3a90d78abdf29a422505aa2b2f1e632p2@Defb23
4.54e-44FFCP PHASE1:Mm9::chr11:101959159..101959163,+#_e3a90d78abdf29a422505aa2b2f1e632p@chr11:101959159..101959163, +
4.54e-44FFCP PHASE2:Mm9::chr2:75866210..75866235,+#_e3a90d78abdf29a422505aa2b2f1e632p@chr2:75866210..75866235, +
4.54e-44FFCP PHASE2:Mm9::chr7:151928014..151928021,+#_e3a90d78abdf29a422505aa2b2f1e632p@chr7:151928014..151928021, +
4.54e-44FFCP PHASE1:Mm9::chr4:123977104..123977120,-#_e3a90d78abdf29a422505aa2b2f1e632p1@ENSMUST00000139012, p1@uc008uqo.1
4.54e-44FFCP PHASE2:Mm9::chr14:103837894..103837900,+#_e3a90d78abdf29a422505aa2b2f1e632p@chr14:103837894..103837900, +
4.54e-44FFCP PHASE1:Mm9::chr14:51627586..51627595,+#_e3a90d78abdf29a422505aa2b2f1e632p4@Rnase10
4.54e-44FFCP PHASE1:Mm9::chr13:21378296..21378303,+#_e3a90d78abdf29a422505aa2b2f1e632p@chr13:21378296..21378303, +
4.54e-44FFCP PHASE2:Mm9::chr1:90155966..90155989,+#_e3a90d78abdf29a422505aa2b2f1e632p@chr1:90155966..90155989, +
4.54e-44FFCP PHASE2:Mm9::chr18:46301295..46301302,-#_e3a90d78abdf29a422505aa2b2f1e632p@chr18:46301295..46301302, -
4.54e-44FFCP PHASE2:Mm9::chr13:21379065..21379072,-#_e3a90d78abdf29a422505aa2b2f1e632p@chr13:21379065..21379072, -
4.54e-44FFCP PHASE1:Mm9::chr9:35585507..35585517,-#_e3a90d78abdf29a422505aa2b2f1e632p4@Gm17727
4.54e-44FFCP PHASE2:Mm9::chr5:31377177..31377184,+#_e3a90d78abdf29a422505aa2b2f1e632p@chr5:31377177..31377184, +
4.54e-44FFCP PHASE1:Mm9::chr1:39707572..39707583,+#_e3a90d78abdf29a422505aa2b2f1e632p@chr1:39707572..39707583, +
4.54e-44FFCP PHASE1:Mm9::chr15:54678902..54678911,-#_e3a90d78abdf29a422505aa2b2f1e632p@chr15:54678902..54678911, -
4.54e-44FFCP PHASE1:Mm9::chr12:103896102..103896116,-#_e3a90d78abdf29a422505aa2b2f1e632p@chr12:103896102..103896116, -
4.54e-44FFCP PHASE2:Mm9::chr19:24582739..24582748,-#_e3a90d78abdf29a422505aa2b2f1e632p@chr19:24582739..24582748, -
4.54e-44FFCP PHASE2:Mm9::chr11:53938008..53938022,+#_e3a90d78abdf29a422505aa2b2f1e632p11@P4ha2
4.54e-44FFCP PHASE2:Mm9::chr7:31507623..31507631,+#_e3a90d78abdf29a422505aa2b2f1e632p4@Atp4a
4.54e-44FFCP PHASE2:Mm9::chr4:106730107..106730125,-#_e3a90d78abdf29a422505aa2b2f1e632p@chr4:106730107..106730125, -
4.54e-44FFCP PHASE1:Mm9::chr5:31379845..31379855,+#_e3a90d78abdf29a422505aa2b2f1e632p@chr5:31379845..31379855, +
4.54e-44FFCP PHASE2:Mm9::chr16:43230846..43230884,+#_e3a90d78abdf29a422505aa2b2f1e632p@chr16:43230846..43230884, +
4.54e-44FFCP PHASE1:Mm9::chr13:21380610..21380620,-#_e3a90d78abdf29a422505aa2b2f1e632p@chr13:21380610..21380620, -
4.54e-44FFCP PHASE2:Mm9::chr3:146278590..146278595,-#_e3a90d78abdf29a422505aa2b2f1e632p10@Dnase2b
4.54e-44FFCP PHASE2:Mm9::chr13:21381141..21381155,-#_e3a90d78abdf29a422505aa2b2f1e632p@chr13:21381141..21381155, -
4.54e-44FFCP PHASE2:Mm9::chr15:54678983..54678995,-#_e3a90d78abdf29a422505aa2b2f1e632p@chr15:54678983..54678995, -
4.54e-44FFCP PHASE2:Mm9::chr14:52542711..52542716,-#_e3a90d78abdf29a422505aa2b2f1e632p2@Rnase13
4.54e-44FFCP PHASE1:Mm9::chr1:90368977..90368987,+#_e3a90d78abdf29a422505aa2b2f1e632p@chr1:90368977..90368987, +
4.54e-44FFCP PHASE2:Mm9::chrX:50280152..50280179,+#_e3a90d78abdf29a422505aa2b2f1e632p@chrX:50280152..50280179, +
4.54e-44FFCP PHASE2:Mm9::chr18:44261480..44261486,+#_e3a90d78abdf29a422505aa2b2f1e632p@chr18:44261480..44261486, +
4.54e-44FFCP PHASE1:Mm9::chr9:70779586..70779596,+#_e3a90d78abdf29a422505aa2b2f1e632p@chr9:70779586..70779596, +
4.54e-44FFCP PHASE1:Mm9::chr9:26730625..26730636,-#_e3a90d78abdf29a422505aa2b2f1e632p3@Gm1110
4.54e-44FFCP PHASE1:Mm9::chr5:110773731..110773753,+#_e3a90d78abdf29a422505aa2b2f1e632p@chr5:110773731..110773753, +
4.54e-44FFCP PHASE2:Mm9::chr8:19141447..19141469,+#_e3a90d78abdf29a422505aa2b2f1e632p@chr8:19141447..19141469, +
4.54e-44FFCP PHASE2:Mm9::chr2:25677632..25677636,-#_e3a90d78abdf29a422505aa2b2f1e632p@chr2:25677632..25677636, -
4.54e-44FFCP PHASE1:Mm9::chr11:116901496..116901514,-#_e3a90d78abdf29a422505aa2b2f1e632p1@ENSMUST00000150628, p1@ENSMUST00000152401, p1@uc007mmw.1
4.54e-44FFCP PHASE2:Mm9::chr14:51677141..51677148,-#_e3a90d78abdf29a422505aa2b2f1e632p7@Rnase12
4.54e-44FFCP PHASE1:Mm9::chr10:61976287..61976297,-#_e3a90d78abdf29a422505aa2b2f1e632p@chr10:61976287..61976297, -
4.54e-44FFCP PHASE2:Mm9::chr13:21379322..21379338,-#_e3a90d78abdf29a422505aa2b2f1e632p@chr13:21379322..21379338, -
4.54e-44FFCP PHASE2:Mm9::chr6:147624258..147624285,-#_e3a90d78abdf29a422505aa2b2f1e632p@chr6:147624258..147624285, -
4.54e-44FFCP PHASE2:Mm9::chr2:164464249..164464258,-#_e3a90d78abdf29a422505aa2b2f1e632p@chr2:164464249..164464258, -
4.54e-44FFCP PHASE2:Mm9::chr14:51734060..51734066,+#_e3a90d78abdf29a422505aa2b2f1e632p5@Eddm3b
4.54e-44FFCP PHASE1:Mm9::chr3:146278590..146278595,-#_e3a90d78abdf29a422505aa2b2f1e632p10@Dnase2b
4.54e-44FFCP PHASE1:Mm9::chr13:21381777..21381789,-#_e3a90d78abdf29a422505aa2b2f1e632p@chr13:21381777..21381789, -
4.54e-44FFCP PHASE2:Mm9::chr8:126591032..126591039,+#_e3a90d78abdf29a422505aa2b2f1e632p@chr8:126591032..126591039, +
4.54e-44FFCP PHASE2:Mm9::chr1:165219453..165219469,-#_e3a90d78abdf29a422505aa2b2f1e632p11@Prrx1
4.54e-44FFCP PHASE1:Mm9::chrX:20219008..20219045,+#_e3a90d78abdf29a422505aa2b2f1e632p@chrX:20219008..20219045, +
4.54e-44FFCP PHASE1:Mm9::chr7:6204391..6204398,+#_e3a90d78abdf29a422505aa2b2f1e632p2@Gm6792
4.54e-44FFCP PHASE2:Mm9::chr12:104945515..104945524,-#_e3a90d78abdf29a422505aa2b2f1e632p@chr12:104945515..104945524, -
4.54e-44FFCP PHASE2:Mm9::chr2:158083973..158083982,+#_e3a90d78abdf29a422505aa2b2f1e632p3@Bpi
4.54e-44FFCP PHASE1:Mm9::chr18:74784728..74784738,+#_e3a90d78abdf29a422505aa2b2f1e632p@chr18:74784728..74784738, +
4.54e-44FFCP PHASE1:Mm9::chr17:35252614..35252635,-#_e3a90d78abdf29a422505aa2b2f1e632p3@Ly6g5b
4.54e-44FFCP PHASE2:Mm9::chr8:19062951..19062955,+#_e3a90d78abdf29a422505aa2b2f1e632p@chr8:19062951..19062955, +
4.54e-44FFCP PHASE2:Mm9::chr1:89596972..89596981,+#_e3a90d78abdf29a422505aa2b2f1e632p@chr1:89596972..89596981, +
4.54e-44FFCP PHASE2:Mm9::chr11:101959159..101959163,+#_e3a90d78abdf29a422505aa2b2f1e632p@chr11:101959159..101959163, +
4.54e-44FFCP PHASE2:Mm9::chr9:35651679..35651691,-#_e3a90d78abdf29a422505aa2b2f1e632p5@9230110F15Rik
4.54e-44FFCP PHASE1:Mm9::chrX:130496260..130496269,-#_e3a90d78abdf29a422505aa2b2f1e632p@chrX:130496260..130496269, -
4.54e-44FFCP PHASE1:Mm9::chr13:21378968..21378988,-#_e3a90d78abdf29a422505aa2b2f1e632p@chr13:21378968..21378988, -
4.54e-44FFCP PHASE2:Mm9::chr16:22504758..22504766,-#_e3a90d78abdf29a422505aa2b2f1e632p@chr16:22504758..22504766, -
4.54e-44FFCP PHASE1:Mm9::chr2:152302739..152302742,+#_e3a90d78abdf29a422505aa2b2f1e632p5@Defb20
4.54e-44FFCP PHASE2:Mm9::chr2:148625223..148625234,+#_e3a90d78abdf29a422505aa2b2f1e632p@chr2:148625223..148625234, +










Property "Property value" (as page type) with input value "UBPROP:0000001 "Organ that serves as a transient kidney, providing osmoregulation during early developmental stages and then degenerating during metamorphosis.[AAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process., Property "Property value" (as page type) with input value "UBPROP:0000001 "The embryonic kidney, present at the level of the third somite, is composed of two glomeruli fused at the midline, two pronephric tubules, and paired bilateral pronephric ducts that modify the composition of the blood filtrate before delivering it to the cloaca for excretion.Kimmel et al, 1995.[TAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.