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|gostat_on_coexpression_clusters=GO:0042493!response to drug!0.0221113997876872!64240;55244$GO:0006855!multidrug transport!0.0363522643590524!55244$GO:0005017!platelet-derived growth factor receptor activity!0.0363522643590524!5159$GO:0004873!asialoglycoprotein receptor activity!0.0363522643590524!432$GO:0004992!platelet activating factor receptor activity!0.0387711830818315!5159$GO:0030299!cholesterol absorption!0.0458376287579303!64240$GO:0003917!DNA topoisomerase type I activity!0.0458376287579303!116447$GO:0044241!lipid digestion!0.0458376287579303!64240$GO:0050892!intestinal absorption!0.0458376287579303!64240$GO:0003918!DNA topoisomerase (ATP-hydrolyzing) activity!0.0458376287579303!116447$GO:0005160!transforming growth factor beta receptor binding!0.0458376287579303!3626$GO:0016020!membrane!0.0458376287579303!64240;5909;5159;55244;64083;432;7803$GO:0010212!response to ionizing radiation!0.0458376287579303!64240$GO:0006268!DNA unwinding during replication!0.0458376287579303!116447$GO:0006265!DNA topological change!0.0458376287579303!116447$GO:0003916!DNA topoisomerase activity!0.0458376287579303!116447$GO:0015893!drug transport!0.0458376287579303!55244$GO:0032392!DNA geometric change!0.0458376287579303!116447$GO:0032508!DNA duplex unwinding!0.0458376287579303!116447$GO:0022600!digestive system process!0.0459595450544434!64240$GO:0015238!drug transporter activity!0.0483613875409549!55244$GO:0005021!vascular endothelial growth factor receptor activity!0.0483613875409549!5159
 
|gostat_on_coexpression_clusters=GO:0042493!response to drug!0.0221113997876872!64240;55244$GO:0006855!multidrug transport!0.0363522643590524!55244$GO:0005017!platelet-derived growth factor receptor activity!0.0363522643590524!5159$GO:0004873!asialoglycoprotein receptor activity!0.0363522643590524!432$GO:0004992!platelet activating factor receptor activity!0.0387711830818315!5159$GO:0030299!cholesterol absorption!0.0458376287579303!64240$GO:0003917!DNA topoisomerase type I activity!0.0458376287579303!116447$GO:0044241!lipid digestion!0.0458376287579303!64240$GO:0050892!intestinal absorption!0.0458376287579303!64240$GO:0003918!DNA topoisomerase (ATP-hydrolyzing) activity!0.0458376287579303!116447$GO:0005160!transforming growth factor beta receptor binding!0.0458376287579303!3626$GO:0016020!membrane!0.0458376287579303!64240;5909;5159;55244;64083;432;7803$GO:0010212!response to ionizing radiation!0.0458376287579303!64240$GO:0006268!DNA unwinding during replication!0.0458376287579303!116447$GO:0006265!DNA topological change!0.0458376287579303!116447$GO:0003916!DNA topoisomerase activity!0.0458376287579303!116447$GO:0015893!drug transport!0.0458376287579303!55244$GO:0032392!DNA geometric change!0.0458376287579303!116447$GO:0032508!DNA duplex unwinding!0.0458376287579303!116447$GO:0022600!digestive system process!0.0459595450544434!64240$GO:0015238!drug transporter activity!0.0483613875409549!55244$GO:0005021!vascular endothelial growth factor receptor activity!0.0483613875409549!5159
 
|id=C576
 
|id=C576
 +
|ontology_enrichment_celltype=CL:0000136!1.49e-11!15
 +
|ontology_enrichment_disease=
 +
|ontology_enrichment_uberon=UBERON:0007023!2.53e-10!115;UBERON:0009856!6.54e-08!26;UBERON:0007499!1.67e-07!25;UBERON:0009854!2.07e-07!23;UBERON:0000475!2.71e-07!365;UBERON:0002107!3.11e-07!19;UBERON:0006925!3.11e-07!19;UBERON:0008836!3.11e-07!19;UBERON:0008835!5.31e-07!22;UBERON:0003894!5.31e-07!22;UBERON:0002417!5.32e-07!61;UBERON:0000916!5.32e-07!61;UBERON:0009497!7.68e-07!25;UBERON:0000015!7.68e-07!25;UBERON:0002423!7.68e-07!25;UBERON:0006235!7.68e-07!25;UBERON:0004161!7.68e-07!25
 
}}
 
}}

Revision as of 05:55, 21 May 2012


Full id: C576_Hepatocyte_hepatocellular_liver_Intestinal_mature_breast_Prostate



Phase1 CAGE Peaks

  Short description
Hg19::chr10:113987378..113987454,- p@chr10:113987378..113987454
-
Hg19::chr10:7755243..7755254,- p@chr10:7755243..7755254
-
Hg19::chr10:7773844..7773851,+ p@chr10:7773844..7773851
+
Hg19::chr12:57828432..57828442,+ p7@INHBC
Hg19::chr12:57828463..57828472,+ p9@INHBC
Hg19::chr16:85570675..85570678,+ p@chr16:85570675..85570678
+
Hg19::chr17:19437692..19437704,- p1@AK127534
Hg19::chr17:7082861..7082882,- p9@ASGR1
Hg19::chr1:21996247..21996270,- p6@RAP1GAP
Hg19::chr2:20793103..20793113,- p@chr2:20793103..20793113
-
Hg19::chr2:44066386..44066398,- p6@ABCG5
Hg19::chr5:149516966..149516977,- p8@PDGFRB
Hg19::chr5:32174797..32174803,- p17@GOLPH3
Hg19::chr6:64231645..64231678,+ p6@PTP4A1
Hg19::chr8:144417558..144417572,- p7@TOP1MT


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset
data


GO IDGO nameFDR corrected p-value
GO:0042493response to drug0.0221113997876872
GO:0006855multidrug transport0.0363522643590524
GO:0005017platelet-derived growth factor receptor activity0.0363522643590524
GO:0004873asialoglycoprotein receptor activity0.0363522643590524
GO:0004992platelet activating factor receptor activity0.0387711830818315
GO:0030299cholesterol absorption0.0458376287579303
GO:0003917DNA topoisomerase type I activity0.0458376287579303
GO:0044241lipid digestion0.0458376287579303
GO:0050892intestinal absorption0.0458376287579303
GO:0003918DNA topoisomerase (ATP-hydrolyzing) activity0.0458376287579303
GO:0005160transforming growth factor beta receptor binding0.0458376287579303
GO:0016020membrane0.0458376287579303
GO:0010212response to ionizing radiation0.0458376287579303
GO:0006268DNA unwinding during replication0.0458376287579303
GO:0006265DNA topological change0.0458376287579303
GO:0003916DNA topoisomerase activity0.0458376287579303
GO:0015893drug transport0.0458376287579303
GO:0032392DNA geometric change0.0458376287579303
GO:0032508DNA duplex unwinding0.0458376287579303
GO:0022600digestive system process0.0459595450544434
GO:0015238drug transporter activity0.0483613875409549
GO:0005021vascular endothelial growth factor receptor activity0.0483613875409549



Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data


Cell Type
Ontology termp-valuen
fat cell1.49e-1115
Uber Anatomy
Ontology termp-valuen
adult organism2.53e-10115
sac6.54e-0826
epithelial sac1.67e-0725
digestive tract diverticulum2.07e-0723
organism subdivision2.71e-07365
liver3.11e-0719
digestive gland3.11e-0719
liver bud3.11e-0719
hepatic diverticulum5.31e-0722
liver primordium5.31e-0722
abdominal segment of trunk5.32e-0761
abdomen5.32e-0761
epithelium of foregut-midgut junction7.68e-0725
anatomical boundary7.68e-0725
hepatobiliary system7.68e-0725
foregut-midgut junction7.68e-0725
septum transversum7.68e-0725


Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset

data


No analysis results for this cluster

Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data


This analysis result is provided for C0 - C305 clusters.