MCL coexpression mm9:1574

Phase1 CAGE Peaks

	Short description
Mm9::chr11:58136797..58136859,-	p1@Zfp672
Mm9::chr14:119406667..119406720,-	p2@Uggt2
Mm9::chr14:73952558..73952583,+	p2@Sucla2
Mm9::chr16:91619231..91619269,-	p1@Dnajc28
Mm9::chr9:102528530..102528569,-	p1@Cep63

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0004774	succinate-CoA ligase activity	0.03204601427747
GO:0016405	CoA-ligase activity	0.0329610565951019
GO:0016878	acid-thiol ligase activity	0.0329610565951019
GO:0016877	ligase activity, forming carbon-sulfur bonds	0.0329610565951019
GO:0006099	tricarboxylic acid cycle	0.0329610565951019
GO:0046356	acetyl-CoA catabolic process	0.0329610565951019
GO:0009060	aerobic respiration	0.0329610565951019
GO:0009109	coenzyme catabolic process	0.0329610565951019
GO:0045333	cellular respiration	0.0329610565951019
GO:0051187	cofactor catabolic process	0.0329610565951019
GO:0006084	acetyl-CoA metabolic process	0.0329610565951019

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
anatomical conduit	1.34e-07	122
structure with developmental contribution from neural crest	3.88e-07	92
adult organism	6.28e-07	51
tube	9.25e-07	114

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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