Personal tools

MCL coexpression mm9:453: Difference between revisions

From FANTOM5_SSTAR

Jump to: navigation, search
No edit summary
No edit summary
Line 6: Line 6:
|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0003102!5.19e-09!22;UBERON:0002048!7.96e-09!14;UBERON:0000117!7.96e-09!14;UBERON:0000171!7.96e-09!14;UBERON:0000170!7.96e-09!14;UBERON:0005597!7.96e-09!14;UBERON:0000118!7.96e-09!14
|ontology_enrichment_uberon=UBERON:0003102!5.19e-09!22;UBERON:0002048!7.96e-09!14;UBERON:0000117!7.96e-09!14;UBERON:0000171!7.96e-09!14;UBERON:0000170!7.96e-09!14;UBERON:0005597!7.96e-09!14;UBERON:0000118!7.96e-09!14
|tfbs_overrepresentation_for_novel_motifs=0.556227,0.100481,0.510781,1.84325,0.667417,0.656813,0.305009,0.186307,0.768345,0.0241551,0.26934,0.295134,0.0498401,0.845901,0.351364,0,0.482714,0.312712,0.167127,0.89761,0.878946,0.0408122,0.3144,0.0977158,0.523846,0.338177,0.0402178,0.694761,0.126301,0.10762,1.24431,0.574932,0.0927567,0.904269,0.108791,0.178588,0.294993,0.292182,0.075762,0.0613737,0.318773,0.678575,0.00637217,0.354562,0.0559452,0.213039,0.41191,0.26128,0.0241728,0.128181,0.467043,0.360991,0.100464,0.7073,0.723811,0.321095,0.417292,0.284741,0.0367929,0.319396,0.556492,0.369066,0.215066,0.456979,0.330403,0.493315,0.854035,2.6804,0.552202,1.05011,0.158281,1.15547,0.261967,0.755651,0.0343898,0.125122,0.313869,0.401969,0.540754,0.148967,2.74488,0.498379,2.58051,0.0470048,0.646739,0.0847426,1.63864,0.0254035,0.416206,1.35441,0.92132,0.6514,4.80376,0.102076,0.073664,0.231057,0.183077,1.43878,0.412133,0.681961,0.0875773,0.574674,0.690844,0.467576,0.466632,0.677777,0.52055,0.25809,0.463457,0.147333,0.543885,0.692526,0.894157,0.273484,0.928143,0.315992,0.0551807,0.637592,0.483885,0.289365,0.760792,0.438354,0.900811,0.40118,0.980682,0.544138,0.311744,0.580495,0.852575,0.10384,1.6177,0.215942,0.824167,0.332514,0.949083,0.0397143,0.571001,0.681128,0.901468,1.71991,1.32292,1.99712,0.349901,0.584599,0.46084,0.242215,1.87461,1.68046,4.06712,0.672242,0.110319,0.594031,0.708784,0.0677483,0.883035,0.786435,0.361851,0.370626,0.188342,0.196072,0.910663,0.645939,0.544546,0.183389,0.457889,0.325532,0.0869123,0.293837,0.00038779
}}
}}

Revision as of 18:23, 26 November 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr10:33816270..33816273,-p6@Fam26e
Mm9::chr13:49703399..49703432,+p1@Ogn
Mm9::chr13:49718335..49718348,+p@chr13:49718335..49718348
+
Mm9::chr14:47006937..47006958,-p@chr14:47006937..47006958
-
Mm9::chr14:47006973..47006987,-p@chr14:47006973..47006987
-
Mm9::chr15:54684962..54684979,-p@chr15:54684962..54684979
-
Mm9::chr17:80114052..80114087,-p3@Cyp1b1
Mm9::chr1:172040854..172040860,-p9@Ddr2
Mm9::chr1:95196851..95196860,+p@chr1:95196851..95196860
+
Mm9::chr2:125860373..125860382,+p7@Fgf7
Mm9::chr2:125860383..125860401,+p1@Fgf7
Mm9::chr2:125860402..125860415,+p3@Fgf7
Mm9::chr2:125860501..125860530,+p2@Fgf7
Mm9::chr2:125860531..125860544,+p4@Fgf7
Mm9::chr2:125861402..125861426,+p@chr2:125861402..125861426
+
Mm9::chr2:125861431..125861460,+p@chr2:125861431..125861460
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0008083growth factor activity0.00122733627288827
GO:0007500mesodermal cell fate determination0.0162561456218623
GO:0005102receptor binding0.0162561456218623
GO:0021978telencephalon regionalization0.0162561456218623
GO:0048522positive regulation of cellular process0.0162561456218623
GO:0044421extracellular region part0.0162561456218623
GO:0032331negative regulation of chondrocyte differentiation0.0162561456218623
GO:0032330regulation of chondrocyte differentiation0.0162561456218623
GO:0045662negative regulation of myoblast differentiation0.0162561456218623
GO:0001710mesodermal cell fate commitment0.0162561456218623
GO:0048333mesodermal cell differentiation0.0162561456218623
GO:0048518positive regulation of biological process0.0162561456218623
GO:0008284positive regulation of cell proliferation0.0162561456218623
GO:0021904dorsoventral neural tube patterning0.0170144388354342
GO:0030501positive regulation of bone mineralization0.0170144388354342
GO:0005125cytokine activity0.0194654964544927
GO:0045778positive regulation of ossification0.0210468324063134
GO:0021871forebrain regionalization0.0210468324063134
GO:0046852positive regulation of bone remodeling0.0210468324063134
GO:0045669positive regulation of osteoblast differentiation0.0210468324063134
GO:0045843negative regulation of striated muscle development0.0210468324063134
GO:0007167enzyme linked receptor protein signaling pathway0.0210468324063134
GO:0021532neural tube patterning0.0210468324063134
GO:0045661regulation of myoblast differentiation0.0210468324063134
GO:0005578proteinaceous extracellular matrix0.0210468324063134
GO:0051145smooth muscle cell differentiation0.0220739524444176
GO:0042127regulation of cell proliferation0.0250632321560463
GO:0045667regulation of osteoblast differentiation0.0273206722856267
GO:0016202regulation of striated muscle development0.028573663789643
GO:0050679positive regulation of epithelial cell proliferation0.0298721632535791
GO:0002062chondrocyte differentiation0.0298721632535791
GO:0030500regulation of bone mineralization0.0298721632535791
GO:0001658ureteric bud branching0.0347489098758318
GO:0005104fibroblast growth factor receptor binding0.0355966978373871
GO:0008283cell proliferation0.0365611800202646
GO:0030282bone mineralization0.0365611800202646
GO:0050678regulation of epithelial cell proliferation0.0365611800202646
GO:0030278regulation of ossification0.0365611800202646
GO:0001709cell fate determination0.0365611800202646
GO:0001707mesoderm formation0.0365611800202646
GO:0048332mesoderm morphogenesis0.0365611800202646
GO:0001649osteoblast differentiation0.0365611800202646
GO:0001934positive regulation of protein amino acid phosphorylation0.0365611800202646
GO:0001704formation of primary germ layer0.0365611800202646
GO:0033240positive regulation of amine metabolic process0.0365611800202646
GO:0045764positive regulation of amino acid metabolic process0.0365611800202646
GO:0007281germ cell development0.0365611800202646
GO:0030509BMP signaling pathway0.0376583279657835
GO:0046850regulation of bone remodeling0.0376583279657835
GO:0050673epithelial cell proliferation0.0391437993405773
GO:0001657ureteric bud development0.0391437993405773
GO:0050381unspecific monooxygenase activity0.0391437993405773
GO:0045445myoblast differentiation0.0416472564852497
GO:0042475odontogenesis of dentine-containing teeth0.0416472564852497
GO:0006468protein amino acid phosphorylation0.0416472564852497
GO:0030218erythrocyte differentiation0.0416472564852497
GO:0042476odontogenesis0.0416472564852497
GO:0016712oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen0.0416472564852497
GO:0005615extracellular space0.0419100510557126
GO:0009953dorsal/ventral pattern formation0.0455312993014895
GO:0016310phosphorylation0.0461018634925893
GO:0001656metanephros development0.0461018634925893
GO:0045597positive regulation of cell differentiation0.0463732300747337
GO:0051216cartilage development0.0476229337557569
GO:0007498mesoderm development0.0478619088067146
GO:0033238regulation of amine metabolic process0.0485354375447023
GO:0001932regulation of protein amino acid phosphorylation0.0485354375447023
GO:0006521regulation of amino acid metabolic process0.0485354375447023
GO:0042325regulation of phosphorylation0.0490433248316235
GO:0051174regulation of phosphorus metabolic process0.0490433248316235
GO:0019220regulation of phosphate metabolic process0.0490433248316235
GO:0048754branching morphogenesis of a tube0.0490433248316235
GO:0008201heparin binding0.0490433248316235
GO:0006793phosphorus metabolic process0.0490433248316235
GO:0006796phosphate metabolic process0.0490433248316235
GO:0007369gastrulation0.0490433248316235
GO:0004714transmembrane receptor protein tyrosine kinase activity0.0490433248316235
GO:0001763morphogenesis of a branching structure0.0490433248316235
GO:0042692muscle cell differentiation0.0490433248316235
GO:0048741skeletal muscle fiber development0.0490433248316235
GO:0030324lung development0.0490433248316235
GO:0048747muscle fiber development0.0490433248316235
GO:0030323respiratory tube development0.0490433248316235
GO:0021915neural tube development0.0490433248316235



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
surface structure5.19e-0922
lung7.96e-0914
respiratory tube7.96e-0914
respiration organ7.96e-0914
pair of lungs7.96e-0914
lung primordium7.96e-0914
lung bud7.96e-0914


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}