Coexpression cluster:C1011: Difference between revisions
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{{Coexpression_clusters | 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repair!1.36711281599438e-07!9401;3978;5426;5424;10036$GO:0006974!response to DNA damage stimulus!1.36711281599438e-07!9401;3978;5426;5424;10036$GO:0006259!DNA metabolic process!1.36711281599438e-07!9401;3978;5426;5424;10036;1786$GO:0009719!response to endogenous stimulus!2.2353665367932e-07!9401;3978;5426;5424;10036$GO:0006260!DNA replication!5.81249790921492e-06!3978;5426;5424;10036$GO:0006950!response to stress!9.73788887599282e-06!9401;3978;5426;5424;10036$GO:0000731!DNA synthesis during DNA repair!1.30963982036091e-05!5426;5424$GO:0003682!chromatin binding!1.70270067455608e-05!5426;5424;10036$GO:0007049!cell cycle!9.94130900183607e-05!3978;5426;5424;10036$GO:0006139!nucleobase, nucleoside, nucleotide and nucleic acid metabolic process!0.00043621865655787!9401;3978;5426;5424;10036;1786$GO:0003887!DNA-directed DNA polymerase activity!0.000449255144653721!5426;5424$GO:0005634!nucleus!0.000449255144653721!9401;3978;5426;5424;10036;1786$GO:0051329!interphase of mitotic cell cycle!0.00119150193290442!5426;5424$GO:0051325!interphase!0.00124071983685884!5426;5424$GO:0043283!biopolymer metabolic process!0.00182299496202717!9401;3978;5426;5424;10036;1786$GO:0043231!intracellular membrane-bound organelle!0.00296693105816845!9401;3978;5426;5424;10036;1786$GO:0043227!membrane-bound organelle!0.00296693105816845!9401;3978;5426;5424;10036;1786$GO:0006335!DNA replication-dependent nucleosome assembly!0.00296693105816845!10036$GO:0045875!negative regulation of sister chromatid cohesion!0.00296693105816845!9401$GO:0007063!regulation of sister chromatid cohesion!0.00296693105816845!9401$GO:0006310!DNA recombination!0.0039538293047545!9401;3978$GO:0016779!nucleotidyltransferase activity!0.00494415731932331!5426;5424$GO:0003891!delta DNA polymerase activity!0.00494415731932331!5424$GO:0003910!DNA ligase (ATP) activity!0.00494415731932331!3978$GO:0003886!DNA (cytosine-5-)-methyltransferase activity!0.00549310385928867!1786$GO:0003893!epsilon DNA polymerase activity!0.00549310385928867!5426$GO:0003909!DNA ligase activity!0.00549310385928867!3978$GO:0043229!intracellular organelle!0.00574075701982397!9401;3978;5426;5424;10036;1786$GO:0043226!organelle!0.00574075701982397!9401;3978;5426;5424;10036;1786$GO:0009008!DNA-methyltransferase activity!0.00574075701982397!1786$GO:0005678!chromatin assembly complex!0.00574075701982397!10036$GO:0003676!nucleic acid binding!0.00618596197214122!9401;3978;5426;5424;1786$GO:0043170!macromolecule metabolic process!0.00633756424988399!9401;3978;5426;5424;10036;1786$GO:0000278!mitotic cell cycle!0.00663322789314192!5426;5424$GO:0003677!DNA binding!0.00686763962456978!3978;5426;5424;1786$GO:0007062!sister chromatid cohesion!0.00741350756267838!9401$GO:0022403!cell cycle phase!0.00778579769906605!5426;5424$GO:0016886!ligase activity, forming phosphoric ester bonds!0.0109211497937796!3978$GO:0048705!skeletal morphogenesis!0.0112381757070516!9401$GO:0044237!cellular metabolic process!0.0112381757070516!9401;3978;5426;5424;10036;1786$GO:0008270!zinc ion binding!0.0112381757070516!9401;5426;5424;1786$GO:0044238!primary metabolic process!0.0112443768708326!9401;3978;5426;5424;10036;1786$GO:0000084!S phase of mitotic cell cycle!0.0114891233863831!5424$GO:0000166!nucleotide binding!0.0114891233863831!9401;3978;5426;5424$GO:0044424!intracellular part!0.0114891233863831!9401;3978;5426;5424;10036;1786$GO:0000792!heterochromatin!0.0127739844957742!1786$GO:0051276!chromosome organization and biogenesis!0.0127739844957742!9401;10036$GO:0051320!S phase!0.0129621865307859!5424$GO:0006305!DNA alkylation!0.0136268075946318!1786$GO:0006306!DNA methylation!0.0136268075946318!1786$GO:0022402!cell cycle process!0.0158980673489082!5426;5424$GO:0006304!DNA modification!0.0159452447403155!1786$GO:0046914!transition metal ion binding!0.0161135256749198!9401;5426;5424;1786$GO:0005657!replication fork!0.0175430415041266!1786$GO:0009411!response to UV!0.0177610225540556!5424$GO:0000082!G1/S transition of mitotic cell cycle!0.0179711408745799!5426$GO:0016458!gene silencing!0.0197272102767894!1786$GO:0005622!intracellular!0.0205585703501337!9401;3978;5426;5424;10036;1786$GO:0016585!chromatin remodeling complex!0.0205585703501337!10036$GO:0043414!biopolymer methylation!0.0221816836641472!1786$GO:0003678!DNA helicase activity!0.023750440581921!9401$GO:0007059!chromosome segregation!0.0281155259347484!9401$GO:0040029!regulation of gene expression, epigenetic!0.0304696161599306!1786$GO:0032259!methylation!0.0326956260140766!1786$GO:0004527!exonuclease activity!0.0326956260140766!5424$GO:0009653!anatomical structure morphogenesis!0.0333618840509839!9401;3978$GO:0016740!transferase activity!0.0350776076463905!5426;5424;1786$GO:0009416!response to light stimulus!0.0350776076463905!5424$GO:0043169!cation binding!0.0350776076463905!9401;5426;5424;1786$GO:0008757!S-adenosylmethionine-dependent methyltransferase activity!0.0362262712413766!1786$GO:0046872!metal ion binding!0.0411364456418694!9401;5426;5424;1786$GO:0009314!response to radiation!0.0413173911846125!5424$GO:0043167!ion binding!0.0425175439882766!9401;5426;5424;1786|id=C1011|kegg_enrichment=hsa03410;Base_excision_repair;2.65E-07!hsa03420;Nucleotide_excision_repair;9.70E-07!hsa03030;DNA_replication;2.12E-06!hsa00240;Pyrimidine_metabolism;4.86E-06!hsa01100;Metabolic_pathways;2.80E-05!hsa00230;Purine_metabolism;6.11E-05|ontology_enrichment_celltype=CL:0000066!2.02e-14!253;CL:0000333!9.42e-07!41|ontology_enrichment_disease=DOID:162!1.26e-44!235;DOID:14566!1.23e-42!239;DOID:2531!4.11e-25!51;DOID:0060083!4.11e-25!51;DOID:0050686!1.31e-22!137;DOID:1240!5.06e-22!39;DOID:0050687!1.20e-21!143;DOID:8692!1.64e-18!31;DOID:305!1.05e-17!106|ontology_enrichment_uberon=|pathway_enrichment=0.000478826714662831;0.0233151777216594;2;163;Purine metabolism (KEGG):00230!0.000180580969984339;0.0095256461666739;2;100;Pyrimidine metabolism (KEGG):00240!3.67416886898525e-08;7.75249631355887e-06;3;36;DNA replication (KEGG):03030!3.07978931231787e-08;7.75249631355887e-06;3;34;Base excision repair (KEGG):03410!8.89191667316632e-08;1.40714581352857e-05;3;48;Nucleotide excision repair (KEGG):03420!9.29638856460575e-06;0.000653845995710604;2;23;Mismatch repair (KEGG):03430!3.15809823992966e-05;0.00181734198715952;2;42;DNA Replication (Wikipathways):WP1806!1.32453795997426e-06;0.000119776075523386;2;9;Mismatch repair (Wikipathways):WP531!1.01567335750795e-06;0.000107153539217089;3;107;DNA Repair (Reactome):REACT_216!6.67157721853038e-06;0.000527888547416216;3;200;DNA Replication (Reactome):REACT_383!2.59719623007301e-05;0.00164402521363621;3;315;Cell Cycle, Mitotic (Reactome):REACT_152!3.75206069989847e-07;4.75010884607146e-05;3;77;Chromosome Maintenance (Reactome):REACT_22172!3.07978931231787e-08;7.75249631355887e-06;3;34;{PCNA,34} (Static 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Latest revision as of 11:35, 17 September 2013
Full id: C1011_acute_granulocyte_Hodgkin_neuroepithelioma_retinoblastoma_hepatoblastoma_merkel
Phase1 CAGE Peaks
| Hg19::chr12:133263893..133263986,- | p1@POLE |
| Hg19::chr19:10305581..10305646,- | p1@DNMT1 |
| Hg19::chr19:4402613..4402658,+ | p1@CHAF1A |
| Hg19::chr19:48673580..48673630,- | p1@LIG1 |
| Hg19::chr19:50887585..50887619,+ | p1@POLD1 |
| Hg19::chr8:145669791..145669834,- | p1@TONSL |
| Hg19::chr8:145743164..145743236,- | p1@RECQL4 |
| Hg19::chr8:145743237..145743261,- | p2@RECQL4 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| p.value | FDR | nGenes | nPathway | Name |
|---|---|---|---|---|
| 0.000478826714662831 | 0.0233151777216594 | 2 | 163 | Purine metabolism (KEGG):00230 |
| 0.000180580969984339 | 0.0095256461666739 | 2 | 100 | Pyrimidine metabolism (KEGG):00240 |
| 3.67416886898525e-08 | 7.75249631355887e-06 | 3 | 36 | DNA replication (KEGG):03030 |
| 3.07978931231787e-08 | 7.75249631355887e-06 | 3 | 34 | Base excision repair (KEGG):03410 |
| 8.89191667316632e-08 | 1.40714581352857e-05 | 3 | 48 | Nucleotide excision repair (KEGG):03420 |
| 9.29638856460575e-06 | 0.000653845995710604 | 2 | 23 | Mismatch repair (KEGG):03430 |
| 3.15809823992966e-05 | 0.00181734198715952 | 2 | 42 | DNA Replication (Wikipathways):WP1806 |
| 1.32453795997426e-06 | 0.000119776075523386 | 2 | 9 | Mismatch repair (Wikipathways):WP531 |
| 1.01567335750795e-06 | 0.000107153539217089 | 3 | 107 | DNA Repair (Reactome):REACT_216 |
| 6.67157721853038e-06 | 0.000527888547416216 | 3 | 200 | DNA Replication (Reactome):REACT_383 |
| 2.59719623007301e-05 | 0.00164402521363621 | 3 | 315 | Cell Cycle, Mitotic (Reactome):REACT_152 |
| 3.75206069989847e-07 | 4.75010884607146e-05 | 3 | 77 | Chromosome Maintenance (Reactome):REACT_22172 |
| 3.07978931231787e-08 | 7.75249631355887e-06 | 3 | 34 | {PCNA,34} (Static Module):NA |
Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0006281 | DNA repair | 1.36711281599438e-07 |
| GO:0006974 | response to DNA damage stimulus | 1.36711281599438e-07 |
| GO:0006259 | DNA metabolic process | 1.36711281599438e-07 |
| GO:0009719 | response to endogenous stimulus | 2.2353665367932e-07 |
| GO:0006260 | DNA replication | 5.81249790921492e-06 |
| GO:0006950 | response to stress | 9.73788887599282e-06 |
| GO:0000731 | DNA synthesis during DNA repair | 1.30963982036091e-05 |
| GO:0003682 | chromatin binding | 1.70270067455608e-05 |
| GO:0007049 | cell cycle | 9.94130900183607e-05 |
| GO:0006139 | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 0.00043621865655787 |
| GO:0003887 | DNA-directed DNA polymerase activity | 0.000449255144653721 |
| GO:0005634 | nucleus | 0.000449255144653721 |
| GO:0051329 | interphase of mitotic cell cycle | 0.00119150193290442 |
| GO:0051325 | interphase | 0.00124071983685884 |
| GO:0043283 | biopolymer metabolic process | 0.00182299496202717 |
| GO:0043231 | intracellular membrane-bound organelle | 0.00296693105816845 |
| GO:0043227 | membrane-bound organelle | 0.00296693105816845 |
| GO:0006335 | DNA replication-dependent nucleosome assembly | 0.00296693105816845 |
| GO:0045875 | negative regulation of sister chromatid cohesion | 0.00296693105816845 |
| GO:0007063 | regulation of sister chromatid cohesion | 0.00296693105816845 |
| GO:0006310 | DNA recombination | 0.0039538293047545 |
| GO:0016779 | nucleotidyltransferase activity | 0.00494415731932331 |
| GO:0003891 | delta DNA polymerase activity | 0.00494415731932331 |
| GO:0003910 | DNA ligase (ATP) activity | 0.00494415731932331 |
| GO:0003886 | DNA (cytosine-5-)-methyltransferase activity | 0.00549310385928867 |
| GO:0003893 | epsilon DNA polymerase activity | 0.00549310385928867 |
| GO:0003909 | DNA ligase activity | 0.00549310385928867 |
| GO:0043229 | intracellular organelle | 0.00574075701982397 |
| GO:0043226 | organelle | 0.00574075701982397 |
| GO:0009008 | DNA-methyltransferase activity | 0.00574075701982397 |
| GO:0005678 | chromatin assembly complex | 0.00574075701982397 |
| GO:0003676 | nucleic acid binding | 0.00618596197214122 |
| GO:0043170 | macromolecule metabolic process | 0.00633756424988399 |
| GO:0000278 | mitotic cell cycle | 0.00663322789314192 |
| GO:0003677 | DNA binding | 0.00686763962456978 |
| GO:0007062 | sister chromatid cohesion | 0.00741350756267838 |
| GO:0022403 | cell cycle phase | 0.00778579769906605 |
| GO:0016886 | ligase activity, forming phosphoric ester bonds | 0.0109211497937796 |
| GO:0048705 | skeletal morphogenesis | 0.0112381757070516 |
| GO:0044237 | cellular metabolic process | 0.0112381757070516 |
| GO:0008270 | zinc ion binding | 0.0112381757070516 |
| GO:0044238 | primary metabolic process | 0.0112443768708326 |
| GO:0000084 | S phase of mitotic cell cycle | 0.0114891233863831 |
| GO:0000166 | nucleotide binding | 0.0114891233863831 |
| GO:0044424 | intracellular part | 0.0114891233863831 |
| GO:0000792 | heterochromatin | 0.0127739844957742 |
| GO:0051276 | chromosome organization and biogenesis | 0.0127739844957742 |
| GO:0051320 | S phase | 0.0129621865307859 |
| GO:0006305 | DNA alkylation | 0.0136268075946318 |
| GO:0006306 | DNA methylation | 0.0136268075946318 |
| GO:0022402 | cell cycle process | 0.0158980673489082 |
| GO:0006304 | DNA modification | 0.0159452447403155 |
| GO:0046914 | transition metal ion binding | 0.0161135256749198 |
| GO:0005657 | replication fork | 0.0175430415041266 |
| GO:0009411 | response to UV | 0.0177610225540556 |
| GO:0000082 | G1/S transition of mitotic cell cycle | 0.0179711408745799 |
| GO:0016458 | gene silencing | 0.0197272102767894 |
| GO:0005622 | intracellular | 0.0205585703501337 |
| GO:0016585 | chromatin remodeling complex | 0.0205585703501337 |
| GO:0043414 | biopolymer methylation | 0.0221816836641472 |
| GO:0003678 | DNA helicase activity | 0.023750440581921 |
| GO:0007059 | chromosome segregation | 0.0281155259347484 |
| GO:0040029 | regulation of gene expression, epigenetic | 0.0304696161599306 |
| GO:0032259 | methylation | 0.0326956260140766 |
| GO:0004527 | exonuclease activity | 0.0326956260140766 |
| GO:0009653 | anatomical structure morphogenesis | 0.0333618840509839 |
| GO:0016740 | transferase activity | 0.0350776076463905 |
| GO:0009416 | response to light stimulus | 0.0350776076463905 |
| GO:0043169 | cation binding | 0.0350776076463905 |
| GO:0008757 | S-adenosylmethionine-dependent methyltransferase activity | 0.0362262712413766 |
| GO:0046872 | metal ion binding | 0.0411364456418694 |
| GO:0009314 | response to radiation | 0.0413173911846125 |
| GO:0043167 | ion binding | 0.0425175439882766 |
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br><br>disease_data<br>
| Ontology term | p-value | n |
|---|---|---|
| epithelial cell | 2.02e-14 | 253 |
| migratory neural crest cell | 9.42e-07 | 41 |
| Ontology term | p-value | n |
|---|---|---|
| cancer | 1.26e-44 | 235 |
| disease of cellular proliferation | 1.23e-42 | 239 |
| hematologic cancer | 4.11e-25 | 51 |
| immune system cancer | 4.11e-25 | 51 |
| organ system cancer | 1.31e-22 | 137 |
| leukemia | 5.06e-22 | 39 |
| cell type cancer | 1.20e-21 | 143 |
| myeloid leukemia | 1.64e-18 | 31 |
| carcinoma | 1.05e-17 | 106 |
Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 5.21858 |
| MA0004.1 | 0.455723 |
| MA0006.1 | 1.47431 |
| MA0007.1 | 0.437331 |
| MA0009.1 | 0.918715 |
| MA0014.1 | 4.92777 |
| MA0017.1 | 0.337901 |
| MA0019.1 | 0.602411 |
| MA0024.1 | 3.16573 |
| MA0025.1 | 1.05265 |
| MA0027.1 | 2.5321 |
| MA0028.1 | 0.846854 |
| MA0029.1 | 0.832916 |
| MA0030.1 | 0.821423 |
| MA0031.1 | 0.756713 |
| MA0038.1 | 0.557409 |
| MA0040.1 | 0.838784 |
| MA0041.1 | 0.474018 |
| MA0042.1 | 0.442535 |
| MA0043.1 | 0.919032 |
| MA0046.1 | 0.90778 |
| MA0048.1 | 1.08711 |
| MA0050.1 | 0.443405 |
| MA0051.1 | 0.553205 |
| MA0052.1 | 0.842664 |
| MA0055.1 | 0.524515 |
| MA0056.1 | 0 |
| MA0057.1 | 0.632427 |
| MA0058.1 | 0.950944 |
| MA0059.1 | 0.361075 |
| MA0060.1 | 2.3723 |
| MA0061.1 | 0.961853 |
| MA0063.1 | 0 |
| MA0066.1 | 0.557833 |
| MA0067.1 | 1.23721 |
| MA0068.1 | 0.133123 |
| MA0069.1 | 0.903908 |
| MA0070.1 | 0.892666 |
| MA0071.1 | 0.518907 |
| MA0072.1 | 0.888148 |
| MA0073.1 | 0.326687 |
| MA0074.1 | 0.552456 |
| MA0076.1 | 0.377799 |
| MA0077.1 | 0.880402 |
| MA0078.1 | 0.652193 |
| MA0081.1 | 0.361233 |
| MA0083.1 | 0.926258 |
| MA0084.1 | 1.42483 |
| MA0087.1 | 0.885691 |
| MA0088.1 | 1.6523 |
| MA0089.1 | 0 |
| MA0090.1 | 0.391903 |
| MA0091.1 | 0.458301 |
| MA0092.1 | 0.421159 |
| MA0093.1 | 0.818737 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.571227 |
| MA0101.1 | 0.825856 |
| MA0103.1 | 0.291333 |
| MA0105.1 | 0.988431 |
| MA0106.1 | 1.45807 |
| MA0107.1 | 0.666147 |
| MA0108.2 | 0.753643 |
| MA0109.1 | 0 |
| MA0111.1 | 0.405141 |
| MA0113.1 | 0.614917 |
| MA0114.1 | 0.231781 |
| MA0115.1 | 1.1606 |
| MA0116.1 | 0.673701 |
| MA0117.1 | 0.956472 |
| MA0119.1 | 0.913661 |
| MA0122.1 | 0.982472 |
| MA0124.1 | 1.11898 |
| MA0125.1 | 1.0347 |
| MA0130.1 | 0 |
| MA0131.1 | 1.60834 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 0.949204 |
| MA0136.1 | 0.564434 |
| MA0139.1 | 0.470675 |
| MA0140.1 | 0.516266 |
| MA0141.1 | 0.359385 |
| MA0142.1 | 0.724856 |
| MA0143.1 | 0.615094 |
| MA0144.1 | 0.623945 |
| MA0145.1 | 0.830366 |
| MA0146.1 | 4.05934 |
| MA0147.1 | 0.681318 |
| MA0148.1 | 0.480298 |
| MA0149.1 | 0.506665 |
| MA0062.2 | 0.485915 |
| MA0035.2 | 0.515566 |
| MA0039.2 | 7.27445 |
| MA0138.2 | 0.653421 |
| MA0002.2 | 0.179788 |
| MA0137.2 | 0.86081 |
| MA0104.2 | 0.55506 |
| MA0047.2 | 0.586412 |
| MA0112.2 | 0.79629 |
| MA0065.2 | 0.226158 |
| MA0150.1 | 0.386144 |
| MA0151.1 | 0 |
| MA0152.1 | 0.52279 |
| MA0153.1 | 1.01778 |
| MA0154.1 | 0.577214 |
| MA0155.1 | 0.764865 |
| MA0156.1 | 0.865715 |
| MA0157.1 | 0.697424 |
| MA0158.1 | 0 |
| MA0159.1 | 0.243637 |
| MA0160.1 | 0.495355 |
| MA0161.1 | 0 |
| MA0162.1 | 7.09066 |
| MA0163.1 | 0.493198 |
| MA0164.1 | 0.627336 |
| MA0080.2 | 0.303167 |
| MA0018.2 | 0.599912 |
| MA0099.2 | 0.523145 |
| MA0079.2 | 5.96581 |
| MA0102.2 | 1.46209 |
| MA0258.1 | 0.603127 |
| MA0259.1 | 1.99938 |
| MA0442.1 | 0 |
ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data
(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)
| TF | #promoters | Enrichment | p-value | q-value |
|---|---|---|---|---|
| ATF3#467 | 3 | 8.42369044725328 | 0.00417116638960993 | 0.0198701170664327 |
| BRCA1#672 | 5 | 12.6151441520149 | 1.47177326411908e-05 | 0.000349342108934846 |
| CCNT2#905 | 8 | 6.33620157696263 | 3.84606837428661e-07 | 1.87437953776071e-05 |
| CHD2#1106 | 6 | 7.75801712558764 | 1.92157406469162e-05 | 0.000434200073003738 |
| E2F1#1869 | 8 | 4.90738921487932 | 2.97124777369457e-06 | 0.000101443003019577 |
| E2F4#1874 | 8 | 12.6680603152844 | 1.5050509647149e-09 | 1.3332147387944e-07 |
| E2F6#1876 | 8 | 5.01715573169739 | 2.48928731545241e-06 | 8.77713294863383e-05 |
| EGR1#1958 | 7 | 4.36465670795887 | 8.58120841941444e-05 | 0.00128581467161438 |
| ELF1#1997 | 8 | 4.25809795880754 | 9.24826870984006e-06 | 0.000246397942802803 |
| HEY1#23462 | 8 | 4.04011104310571 | 1.4081650274634e-05 | 0.000338864855537443 |
| HMGN3#9324 | 5 | 5.11159232709412 | 0.00110951597588993 | 0.00770764527111667 |
| IRF1#3659 | 8 | 7.6371637535639 | 8.63190100943299e-08 | 5.12802678910223e-06 |
| IRF3#3661 | 2 | 11.7454880528724 | 0.0116448804945314 | 0.0425297130356821 |
| MAX#4149 | 6 | 4.83941663175534 | 0.000291750431370536 | 0.0030965572461288 |
| MXI1#4601 | 5 | 6.22598226797456 | 0.000439395490353943 | 0.00409403386716705 |
| MYC#4609 | 7 | 4.56949663765823 | 6.28392411465611e-05 | 0.00102641030749229 |
| NFYA#4800 | 3 | 6.90959276243645 | 0.00727972723713068 | 0.030121129627142 |
| NFYB#4801 | 4 | 8.37989662676823 | 0.000729691402927855 | 0.00581609100437932 |
| NRF1#4899 | 5 | 7.63142465481932 | 0.000166888299471845 | 0.00204525312233513 |
| PAX5#5079 | 6 | 5.00217414838337 | 0.000241608451547577 | 0.00262874727275523 |
| PBX3#5090 | 3 | 8.21794225752905 | 0.00447320658280844 | 0.0211660575526428 |
| POLR2A#5430 | 8 | 2.14745317655807 | 0.00221072578897191 | 0.0127139862706188 |
| RFX5#5993 | 4 | 6.02395541359755 | 0.0025264968061986 | 0.0139907104953645 |
| SIN3A#25942 | 8 | 5.40888472681514 | 1.36410592556506e-06 | 5.34781752102437e-05 |
| SP1#6667 | 8 | 5.6983813781409 | 8.98832477855329e-07 | 3.86150411989851e-05 |
| SP2#6668 | 3 | 9.80757393519174 | 0.00270718466508561 | 0.0148855248624237 |
| SRF#6722 | 4 | 6.8985891310839 | 0.00152207190456878 | 0.00970000412748713 |
| TAF1#6872 | 8 | 3.34304628574529 | 6.40776711117462e-05 | 0.00104304985867202 |
| TBP#6908 | 8 | 3.70677068709639 | 2.80450451364125e-05 | 0.000591836021216767 |
| TFAP2A#7020 | 3 | 6.19448788989186 | 0.00986148386238029 | 0.0370462757851565 |
| YY1#7528 | 6 | 3.68337806239039 | 0.00136063115499274 | 0.0089564450520791 |
| ZNF143#7702 | 5 | 8.43804784514244 | 0.000103101732172918 | 0.00144167114826715 |
Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data
This analysis result is provided for C0 - C305 clusters.
