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DOID:1240

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Name:leukemia
Namespace:FANTOM
Definition:"A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells." [url:http://en.wikipedia.org/wiki/Leukemia]
Xrefs:
links:

ICD9CM:208
ICD9CM:208.9
MSH:D007938
NCI:C3161
SNOMEDCT_2010_1_31:154598008
SNOMEDCT_2010_1_31:188762002
SNOMEDCT_2010_1_31:188767008
SNOMEDCT_2010_1_31:190024009
SNOMEDCT_2010_1_31:190025005
SNOMEDCT_2010_1_31:190029004
SNOMEDCT_2010_1_31:190071003
SNOMEDCT_2010_1_31:255049003
SNOMEDCT_2010_1_31:87163000
SNOMEDCT_2010_1_31:93143009

UMLS_CUI:C0023418
Alt_id: DOID:9145

Ontology association<br>Each term has an is_a parent in the Disease Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to DISEASE ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:DOID:2531(hematologic cancer)



Children


is a:DOID:1036 (chronic leukemia),DOID:1037 (lymphoblastic leukemia),DOID:12603 (acute leukemia),DOID:8692 (myeloid leukemia)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples

Human (Homo sapiens)

  • 10399-106A3 (acute myeloid leukemia (FAB M5) cell line:THP-1 (fresh))
  • 10400-106A4 (acute myeloid leukemia (FAB M5) cell line:THP-1 (revived))
  • 10405-106A9 (acute myeloid leukemia (FAB M5) cell line:THP-1 (thawed))
  • 10409-106B4 (chronic myelogenous leukemia cell line:KU812)
  • 10416-106C2 (chronic lymphocytic leukemia (T-CLL) cell line:SKW-3)
  • 10421-106C7 (adult T-cell leukemia cell line:ATN-1)
  • 10429-106D6 (acute lymphoblastic leukemia (T-ALL) cell line:HPB-ALL)
  • 10454-106G4 (chronic myelogenous leukemia cell line:K562)
  • 10455-106G5 (acute lymphoblastic leukemia (B-ALL) cell line:BALL-1)
  • 10464-106H5 (acute lymphoblastic leukemia (T-ALL) cell line:Jurkat)

... further results Mouse (Mus musculus)

  • 10399-106A3 (acute myeloid leukemia (FAB M5) cell line:THP-1 (fresh))
  • 10400-106A4 (acute myeloid leukemia (FAB M5) cell line:THP-1 (revived))
  • 10405-106A9 (acute myeloid leukemia (FAB M5) cell line:THP-1 (thawed))
  • 10409-106B4 (chronic myelogenous leukemia cell line:KU812)
  • 10416-106C2 (chronic lymphocytic leukemia (T-CLL) cell line:SKW-3)
  • 10421-106C7 (adult T-cell leukemia cell line:ATN-1)
  • 10429-106D6 (acute lymphoblastic leukemia (T-ALL) cell line:HPB-ALL)
  • 10454-106G4 (chronic myelogenous leukemia cell line:K562)
  • 10455-106G5 (acute lymphoblastic leukemia (B-ALL) cell line:BALL-1)
  • 10464-106H5 (acute lymphoblastic leukemia (T-ALL) cell line:Jurkat)

... further results

Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with DOID:1240 (leukemia), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data


P-valueFFCPShort description
3.78e-103FFCP PHASE1:Hg19::chr6:135513595..135513617,+#_3b016bbf75b8d0aae2ccd0a938aa331dp4@MYB
3.78e-103FFCP PHASE2:Hg19::chr6:135513595..135513617,+#_3b016bbf75b8d0aae2ccd0a938aa331dp4@MYB
7.48e-96FFCP PHASE1:Hg19::chr12:58329776..58329791,-#_de170edf54466305f1ef07b8fbaa3466p3@ENST00000547492
7.48e-96FFCP PHASE2:Hg19::chr12:58329776..58329791,-#_de170edf54466305f1ef07b8fbaa3466p3@ENST00000547492
6.39e-95FFCP PHASE1:Hg19::chr16:29674970..29675007,+#_3b5137f05a3873cb4003a806e9cce1d8p4@SPN
6.39e-95FFCP PHASE2:Hg19::chr16:29674970..29675007,+#_3b5137f05a3873cb4003a806e9cce1d8p4@SPN
3.4e-94FFCP PHASE1:Hg19::chr6:68598314..68598325,-#_2c95962b21acf34a5695217b20dbcb8cp@chr6:68598314..68598325, -
3.4e-94FFCP PHASE2:Hg19::chr6:68598314..68598325,-#_2c95962b21acf34a5695217b20dbcb8cp@chr6:68598314..68598325, -
2.68e-92FFCP PHASE1:Hg19::chr12:58329793..58329806,-#_eb17f0825cf32b4062f85e5d6bd56b60p2@ENST00000547492
2.68e-92FFCP PHASE2:Hg19::chr12:58329793..58329806,-#_eb17f0825cf32b4062f85e5d6bd56b60p2@ENST00000547492
4.68e-91FFCP PHASE1:Hg19::chr6:68598272..68598298,-#_a003dbefa436770682067a2a3d403e04p@chr6:68598272..68598298, -
4.68e-91FFCP PHASE2:Hg19::chr6:68598272..68598298,-#_a003dbefa436770682067a2a3d403e04p@chr6:68598272..68598298, -
2.96e-89FFCP PHASE2:Hg19::chr6:68596384..68596400,-#_a1698cae91317db36b5031f8a7f7380ap@chr6:68596384..68596400, -
2.96e-89FFCP PHASE1:Hg19::chr6:68596384..68596400,-#_a1698cae91317db36b5031f8a7f7380ap@chr6:68596384..68596400, -
1.58e-86FFCP PHASE2:Mm9::chr11:102331415..102331424,-#_4f59dd18e104717a79d3a5dd3049fefdp9@Itga2b
1.58e-86FFCP PHASE2:Mm9::chr10:76688464..76688474,+#_4f59dd18e104717a79d3a5dd3049fefdp@chr10:76688464..76688474, +
1.58e-86FFCP PHASE1:Mm9::chr11:102331415..102331424,-#_4f59dd18e104717a79d3a5dd3049fefdp9@Itga2b
1.58e-86FFCP PHASE1:Mm9::chr10:76688454..76688462,+#_4f59dd18e104717a79d3a5dd3049fefdp@chr10:76688454..76688462, +
1.58e-86FFCP PHASE1:Mm9::chr10:76688464..76688474,+#_4f59dd18e104717a79d3a5dd3049fefdp@chr10:76688464..76688474, +
1.58e-86FFCP PHASE2:Mm9::chr10:76688454..76688462,+#_4f59dd18e104717a79d3a5dd3049fefdp@chr10:76688454..76688462, +
1.84e-86FFCP PHASE1:Hg19::chr12:58329762..58329773,-#_2fdfc0cab71767590bb07beb58380422p5@ENST00000547492
1.84e-86FFCP PHASE2:Hg19::chr12:58329762..58329773,-#_2fdfc0cab71767590bb07beb58380422p5@ENST00000547492
1.62e-85FFCP PHASE1:Hg19::chr6:135533394..135533403,+#_2ec16243574e23d40d5835b793f7b923p@chr6:135533394..135533403, +
1.62e-85FFCP PHASE2:Hg19::chr6:135533394..135533403,+#_2ec16243574e23d40d5835b793f7b923p@chr6:135533394..135533403, +
3.6e-85FFCP PHASE1:Hg19::chr6:68592986..68593000,-#_bde8bda59c30c868c51525369a683e5dp@chr6:68592986..68593000, -
3.6e-85FFCP PHASE2:Hg19::chr6:68592986..68593000,-#_bde8bda59c30c868c51525369a683e5dp@chr6:68592986..68593000, -
3.77e-85FFCP PHASE1:Hg19::chr6:68598245..68598268,-#_7cc31a5c760572801848310dc47bce2ap@chr6:68598245..68598268, -
3.77e-85FFCP PHASE2:Hg19::chr6:68598245..68598268,-#_7cc31a5c760572801848310dc47bce2ap@chr6:68598245..68598268, -
1.61e-84FFCP PHASE1:Hg19::chr6:68598507..68598519,-#_b163918b192f0096fce296b9757f90acp@chr6:68598507..68598519, -
1.61e-84FFCP PHASE2:Hg19::chr6:68598507..68598519,-#_b163918b192f0096fce296b9757f90acp@chr6:68598507..68598519, -
2.52e-84FFCP PHASE1:Hg19::chr6:68598587..68598598,-#_d048f13b3bb24475d4e683781d993ecdp@chr6:68598587..68598598, -
2.52e-84FFCP PHASE2:Hg19::chr6:68598587..68598598,-#_d048f13b3bb24475d4e683781d993ecdp@chr6:68598587..68598598, -
5.25e-84FFCP PHASE1:Hg19::chr16:29675010..29675041,+#_4d798d13addb274d38c5f8bc050cda6bp5@SPN
5.25e-84FFCP PHASE2:Hg19::chr16:29675010..29675041,+#_4d798d13addb274d38c5f8bc050cda6bp5@SPN
2.83e-80FFCP PHASE1:Hg19::chr19:695494..695510,-#_5a0c0dd7fb3fa55eec0104d3c5b506a8p3@PRSS57
2.83e-80FFCP PHASE2:Hg19::chr19:695494..695510,-#_5a0c0dd7fb3fa55eec0104d3c5b506a8p3@PRSS57
5.88e-80FFCP PHASE1:Hg19::chr11:33913475..33913549,-#_aef20964126286b005630e59adb74ed9p5@LMO2
5.88e-80FFCP PHASE2:Hg19::chr11:33913475..33913549,-#_aef20964126286b005630e59adb74ed9p5@LMO2
1.29e-79FFCP PHASE1:Hg19::chr6:68591611..68591627,-#_b541f1de51fa1555575d7dbfcb4bf106p@chr6:68591611..68591627, -
1.29e-79FFCP PHASE2:Hg19::chr6:68591611..68591627,-#_b541f1de51fa1555575d7dbfcb4bf106p@chr6:68591611..68591627, -
1.29e-79FFCP PHASE1:Hg19::chr6:68593536..68593560,-#_b541f1de51fa1555575d7dbfcb4bf106p@chr6:68593536..68593560, -
1.29e-79FFCP PHASE2:Hg19::chr6:68593536..68593560,-#_b541f1de51fa1555575d7dbfcb4bf106p@chr6:68593536..68593560, -
2.09e-79FFCP PHASE2:Hg19::chr6:68596826..68596859,-#_dcdd16cfd9b83b38f8f16e3ab13a56e1p@chr6:68596826..68596859, -
2.09e-79FFCP PHASE1:Hg19::chr6:68597599..68597612,-#_dcdd16cfd9b83b38f8f16e3ab13a56e1p@chr6:68597599..68597612, -
2.09e-79FFCP PHASE1:Hg19::chr6:68596698..68596715,-#_dcdd16cfd9b83b38f8f16e3ab13a56e1p@chr6:68596698..68596715, -
2.09e-79FFCP PHASE2:Hg19::chr6:68597599..68597612,-#_dcdd16cfd9b83b38f8f16e3ab13a56e1p@chr6:68597599..68597612, -
2.09e-79FFCP PHASE2:Hg19::chr6:68596698..68596715,-#_dcdd16cfd9b83b38f8f16e3ab13a56e1p@chr6:68596698..68596715, -
2.09e-79FFCP PHASE1:Hg19::chr6:68596826..68596859,-#_dcdd16cfd9b83b38f8f16e3ab13a56e1p@chr6:68596826..68596859, -
1.93e-78FFCP PHASE1:Hg19::chr6:135502472..135502489,+#_0bdc3d6479a106e0d642eba2834d2b14p3@MYB
1.93e-78FFCP PHASE2:Hg19::chr6:135502472..135502489,+#_0bdc3d6479a106e0d642eba2834d2b14p3@MYB
2.09e-77FFCP PHASE1:Hg19::chr1:202129105..202129140,-#_d289c35e85c28529698e69239db691a3p2@PTPN7
2.09e-77FFCP PHASE2:Hg19::chr1:202129105..202129140,-#_d289c35e85c28529698e69239db691a3p2@PTPN7
7.47e-77FFCP PHASE1:Hg19::chr11:17297848..17297868,+#_3897ce3a5e4bc599ddf6a959f3a140fbp9@NUCB2
7.47e-77FFCP PHASE2:Hg19::chr11:17297848..17297868,+#_3897ce3a5e4bc599ddf6a959f3a140fbp9@NUCB2
1.06e-74FFCP PHASE1:Hg19::chr6:68593520..68593534,-#_d8e042452dc985d7145220aa9cd7d9dcp@chr6:68593520..68593534, -
1.06e-74FFCP PHASE1:Hg19::chr6:68595369..68595417,-#_d8e042452dc985d7145220aa9cd7d9dcp@chr6:68595369..68595417, -
1.06e-74FFCP PHASE2:Hg19::chr6:68593520..68593534,-#_d8e042452dc985d7145220aa9cd7d9dcp@chr6:68593520..68593534, -
1.06e-74FFCP PHASE2:Hg19::chr6:68595369..68595417,-#_d8e042452dc985d7145220aa9cd7d9dcp@chr6:68595369..68595417, -
1.7e-74FFCP PHASE1:Hg19::chr6:68596343..68596355,-#_0911214e5fef66bd1b44f37dbbb99830p@chr6:68596343..68596355, -
1.7e-74FFCP PHASE1:Hg19::chr6:68596783..68596797,-#_0911214e5fef66bd1b44f37dbbb99830p@chr6:68596783..68596797, -
1.7e-74FFCP PHASE2:Hg19::chr6:68596343..68596355,-#_0911214e5fef66bd1b44f37dbbb99830p@chr6:68596343..68596355, -
1.7e-74FFCP PHASE2:Hg19::chr6:68596783..68596797,-#_0911214e5fef66bd1b44f37dbbb99830p@chr6:68596783..68596797, -
6.82e-72FFCP PHASE1:Hg19::chr3:18020982..18021001,+#_309d32364d6261e7826f714b9642f0abp@chr3:18020982..18021001, +
6.82e-72FFCP PHASE2:Hg19::chr3:18020982..18021001,+#_309d32364d6261e7826f714b9642f0abp@chr3:18020982..18021001, +
1.36e-71FFCP PHASE1:Hg19::chr22:50523908..50523925,-#_b795c5eb1f107dd59e1175c561e88221p8@MLC1
1.36e-71FFCP PHASE2:Hg19::chr22:50523908..50523925,-#_b795c5eb1f107dd59e1175c561e88221p8@MLC1
1.62e-71FFCP PHASE1:Hg19::chr19:695467..695482,-#_660c7fbcb2045bf4c8ea016d3cf37580p2@PRSS57
1.62e-71FFCP PHASE2:Hg19::chr19:695467..695482,-#_660c7fbcb2045bf4c8ea016d3cf37580p2@PRSS57
5.58e-71FFCP PHASE1:Hg19::chr6:135516978..135516993,+#_0a0febb1a555fc1c8a3746dd8f038f67p7@MYB
5.58e-71FFCP PHASE2:Hg19::chr6:135516978..135516993,+#_0a0febb1a555fc1c8a3746dd8f038f67p7@MYB
8.11e-71FFCP PHASE1:Hg19::chr6:68598984..68598997,-#_2d836f82f6de1b961f7fbc55bc331de3p2@uc003pes.1, p2@uc003pet.1
8.11e-71FFCP PHASE2:Hg19::chr6:68598984..68598997,-#_2d836f82f6de1b961f7fbc55bc331de3p2@uc003pes.1, p2@uc003pet.1
2.97e-70FFCP PHASE1:Hg19::chr6:68596289..68596302,-#_7f16ea159dc368696d4824bc2d899b30p@chr6:68596289..68596302, -
2.97e-70FFCP PHASE2:Hg19::chr6:68596289..68596302,-#_7f16ea159dc368696d4824bc2d899b30p@chr6:68596289..68596302, -
3.0e-70FFCP PHASE1:Hg19::chr1:202130702..202130728,-#_9b0ee045f0da192d3338396b840ecc81p3@PTPN7
3.0e-70FFCP PHASE2:Hg19::chr1:202130702..202130728,-#_9b0ee045f0da192d3338396b840ecc81p3@PTPN7
6.05e-70FFCP PHASE1:Hg19::chr6:68599042..68599067,-#_a3519b67f79d798714a9296340ea1cadp1@uc003pes.1, p1@uc003pet.1
6.05e-70FFCP PHASE2:Hg19::chr6:68599042..68599067,-#_a3519b67f79d798714a9296340ea1cadp1@uc003pes.1, p1@uc003pet.1
8.49e-70FFCP PHASE1:Hg19::chr6:68592948..68592958,-#_421152d995d6919610685e29e63536a1p@chr6:68592948..68592958, -
8.49e-70FFCP PHASE2:Hg19::chr6:68592948..68592958,-#_421152d995d6919610685e29e63536a1p@chr6:68592948..68592958, -
8.92e-70FFCP PHASE1:Hg19::chr6:68598534..68598555,-#_14abc2887998125bd622ecfee0886f04p@chr6:68598534..68598555, -
8.92e-70FFCP PHASE2:Hg19::chr6:68598534..68598555,-#_14abc2887998125bd622ecfee0886f04p@chr6:68598534..68598555, -
9.84e-70FFCP PHASE1:Hg19::chr6:68593264..68593275,-#_2230b51a397e4fea1899b7c33e138801p@chr6:68593264..68593275, -
9.84e-70FFCP PHASE2:Hg19::chr6:68593264..68593275,-#_2230b51a397e4fea1899b7c33e138801p@chr6:68593264..68593275, -
1.35e-69FFCP PHASE2:Hg19::chr6:68597438..68597450,-#_65669b8918ba69bf8f73b14b1fe4c532p@chr6:68597438..68597450, -
1.35e-69FFCP PHASE1:Hg19::chr6:68593250..68593259,-#_65669b8918ba69bf8f73b14b1fe4c532p@chr6:68593250..68593259, -
1.35e-69FFCP PHASE2:Hg19::chr6:68593587..68593600,-#_65669b8918ba69bf8f73b14b1fe4c532p@chr6:68593587..68593600, -
1.35e-69FFCP PHASE2:Hg19::chr6:68593250..68593259,-#_65669b8918ba69bf8f73b14b1fe4c532p@chr6:68593250..68593259, -
1.35e-69FFCP PHASE1:Hg19::chr6:68596757..68596769,-#_65669b8918ba69bf8f73b14b1fe4c532p@chr6:68596757..68596769, -
1.35e-69FFCP PHASE2:Hg19::chr6:68596757..68596769,-#_65669b8918ba69bf8f73b14b1fe4c532p@chr6:68596757..68596769, -
1.35e-69FFCP PHASE1:Hg19::chr6:68597438..68597450,-#_65669b8918ba69bf8f73b14b1fe4c532p@chr6:68597438..68597450, -
1.35e-69FFCP PHASE1:Hg19::chr6:68593587..68593600,-#_65669b8918ba69bf8f73b14b1fe4c532p@chr6:68593587..68593600, -
4.05e-69FFCP PHASE1:Hg19::chr8:130560752..130560768,-#_4ae59d82190171b6d556037d8d0d87dfp@chr8:130560752..130560768, -
4.05e-69FFCP PHASE2:Hg19::chr8:130560752..130560768,-#_4ae59d82190171b6d556037d8d0d87dfp@chr8:130560752..130560768, -
1.38e-67FFCP PHASE1:Hg19::chr6:135526382..135526388,+#_5e234e4e5108e58d4777282dd1510b34p@chr6:135526382..135526388, +
1.38e-67FFCP PHASE2:Hg19::chr6:135526382..135526388,+#_5e234e4e5108e58d4777282dd1510b34p@chr6:135526382..135526388, +
3.05e-67FFCP PHASE1:Hg19::chr16:89043605..89043625,-#_d0546a37882c3c9167181a0ab22af388p6@CBFA2T3
3.05e-67FFCP PHASE2:Hg19::chr16:89043605..89043625,-#_d0546a37882c3c9167181a0ab22af388p6@CBFA2T3
7.28e-67FFCP PHASE1:Hg19::chr12:58329689..58329704,-#_eee80096774b4903575a992a89c96248p4@ENST00000547492
7.28e-67FFCP PHASE2:Hg19::chr12:58329689..58329704,-#_eee80096774b4903575a992a89c96248p4@ENST00000547492