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MCL coexpression mm9:858: Difference between revisions

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{{MCL_coexpression_mm9
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|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0004111!3.03e-08!122;UBERON:0007023!1.11e-07!51;UBERON:0000025!4.61e-07!114
|tfbs_overrepresentation_for_novel_motifs=0.393008,1.66496,0.367606,0.434198,0.260188,0.448401,0.538088,0.515265,0.181564,1.0625,0.494602,0.526159,0.992329,0.550255,0.275867,0,0.742571,0.252772,0.483643,0.29826,0.332107,0.837949,1.35437,0.258745,0.374936,0.577606,0.153291,0.469052,0.818708,0.118137,1.15331,0.843667,0.699026,0.136998,1.38756,0.903852,1.26012,3.29295,0.631914,0.195877,0.256422,0.460258,0.0558565,1.39283,0.663502,0.423266,0.662995,0.484612,0.0447507,0.305876,1.72213,0.604356,0.112729,0.985264,1.00271,0.557354,0.844204,0.513517,0.877107,1.367,0.823643,0.613749,0.560836,0.713876,4.70185,0.754324,1.139,1.48833,0.818971,1.34113,0.922232,0.178433,0.236196,1.03623,2.67198,1.32088,1.35784,0.651651,0.806481,2.42794,0.179489,0.759925,0.612313,0.167672,0.920903,3.70342,1.24076,0.376919,0.667883,1.65055,1.20871,0.925879,0.856465,0.265734,1.16941,0.202284,0.1711,0.859272,0.663249,1.12826,0.242106,0.843387,0.967837,0.725721,0.724668,1.16334,3.07422,1.20804,0.340849,0.333829,0.386136,0.96962,0.337254,0.499714,1.21576,0.254749,1.82084,1.11602,1.76093,0.238599,1.04163,0.692953,0.579418,0.650748,1.26989,0.810177,0.546178,1.97891,1.13749,0.268537,0.950857,0.427043,1.10792,0.570914,1.23736,0.220515,0.401212,0.461647,1.18819,2.01886,1.6187,1.14372,0.591394,1.98802,0.718197,0.460705,0.666107,1.9792,0.403515,1.33415,1.82213,1.66843,0.986833,0.207643,0.569994,1.06851,0.605358,0.287226,0.39061,0.400939,1.1977,0.920047,0.810622,4.69479,0.714896,0.562634,1.2562,0.524587,0.166768
}}

Latest revision as of 16:00, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr10:127806178..127806254,-p@chr10:127806178..127806254
-
Mm9::chr11:60541983..60542004,+p2@Smcr7
Mm9::chr11:94902580..94902585,-p6@Pdk2
Mm9::chr11:94902590..94902611,-p3@Pdk2
Mm9::chr11:94902622..94902644,-p2@Pdk2
Mm9::chr11:94902649..94902688,-p1@Pdk2
Mm9::chr17:36034287..36034314,-p1@2310061I04Rik
Mm9::chr8:23587095..23587158,-p2@AI316807


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0006086acetyl-CoA biosynthetic process from pyruvate0.0124219511511219
GO:0004740pyruvate dehydrogenase (acetyl-transferring) kinase activity0.0124219511511219
GO:0018106peptidyl-histidine phosphorylation0.0124219511511219
GO:0006085acetyl-CoA biosynthetic process0.0124219511511219
GO:0018202peptidyl-histidine modification0.0124219511511219
GO:0004673protein histidine kinase activity0.0172489287925781
GO:0016775phosphotransferase activity, nitrogenous group as acceptor0.0206941778467661
GO:0006090pyruvate metabolic process0.0271506902753816
GO:0006084acetyl-CoA metabolic process0.0390461747357361



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
anatomical conduit3.03e-08122
adult organism1.11e-0751
tube4.61e-07114


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.11.1343
MA0004.12.89405
MA0006.10.271714
MA0007.11.07722
MA0009.10.870101
MA0014.11.54572
MA0017.10.296816
MA0019.10.688051
MA0024.10.826339
MA0025.11.10341
MA0027.12.51754
MA0028.10.281528
MA0029.10.804619
MA0030.10.811181
MA0031.10.775627
MA0038.10.577528
MA0040.10.882616
MA0041.10.360875
MA0042.10.348174
MA0043.10.966833
MA0046.10.906029
MA0048.10.685543
MA0050.10.472794
MA0051.10.586414
MA0052.10.890676
MA0055.10.117901
MA0056.10
MA0057.10.643187
MA0058.13.37914
MA0059.11.6636
MA0060.15.92753
MA0061.10.224905
MA0063.10
MA0066.10.566617
MA0067.11.21448
MA0068.10.319589
MA0069.10.891016
MA0070.10.881319
MA0071.10.471969
MA0072.10.872842
MA0073.10.00296875
MA0074.10.531046
MA0076.10.315013
MA0077.10.851175
MA0078.10.61926
MA0081.10.375851
MA0083.10.96604
MA0084.11.54225
MA0087.10.922929
MA0088.10.064239
MA0089.10
MA0090.10.401197
MA0091.10.447561
MA0092.10.401504
MA0093.13.04876
MA0095.10
MA0098.10
MA0100.10.519598
MA0101.10.362124
MA0103.10.307078
MA0105.10.41549
MA0106.10.626997
MA0107.10.301222
MA0108.20.710846
MA0109.10
MA0111.10.415012
MA0113.11.45892
MA0114.10.222763
MA0115.10.969632
MA0116.10.27152
MA0117.13.55095
MA0119.10.362692
MA0122.10.957212
MA0124.11.16127
MA0125.11.0872
MA0130.10
MA0131.10.683521
MA0132.10
MA0133.10
MA0135.11.00325
MA0136.10.550755
MA0139.10.169849
MA0140.10.519484
MA0141.10.325895
MA0142.10.761136
MA0143.10.615203
MA0144.10.225588
MA0145.10.246409
MA0146.10.385068
MA0147.12.70055
MA0148.10.450593
MA0149.10.367458
MA0062.20.426733
MA0035.20.524137
MA0039.20.254826
MA0138.20.675599
MA0002.20.513194
MA0137.20.32312
MA0104.21.64215
MA0047.20.576767
MA0112.20.2464
MA0065.20.528619
MA0150.10.419883
MA0151.10
MA0152.10.576873
MA0153.11.01988
MA0154.10.100744
MA0155.10.0804339
MA0156.10.314185
MA0157.11.73039
MA0158.10
MA0159.10.246253
MA0160.10.453546
MA0161.10
MA0162.10.439322
MA0163.10.408151
MA0164.10.551114
MA0080.20.302064
MA0018.20.560731
MA0099.20.669311
MA0079.20.685525
MA0102.21.59466
MA0258.10.210437
MA0259.11.2032
MA0442.10
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