MCL coexpression mm9:652: Difference between revisions
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{{MCL_coexpression_mm9 | 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794678253004593,0.94128070561822,0.0760168881589905,0.220572027003917,0.188495428553301|gostat_on_MCL_coexpression=GO:0006066;alcohol metabolic process;0.00410307789521319;18563,218865,19013!GO:0019752;carboxylic acid metabolic process;0.00410307789521319;18563,218865,19013!GO:0006082;organic acid metabolic process;0.00410307789521319;18563,218865,19013!GO:0008812;choline dehydrogenase activity;0.00410307789521319;218865!GO:0004736;pyruvate carboxylase activity;0.00410307789521319;18563!GO:0031455;glycine betaine metabolic process;0.00410307789521319;218865!GO:0006578;betaine biosynthetic process;0.00410307789521319;218865!GO:0031456;glycine betaine biosynthetic process;0.00410307789521319;218865!GO:0019285;glycine betaine biosynthetic process from choline;0.00410307789521319;218865!GO:0006577;betaine metabolic process;0.00410307789521319;218865!GO:0015362;high affinity sodium:dicarboxylate symporter activity;0.00410307789521319;114644!GO:0006006;glucose metabolic process;0.00410307789521319;18563,19013!GO:0019318;hexose metabolic process;0.0065005020284588;18563,19013!GO:0005996;monosaccharide metabolic process;0.0065005020284588;18563,19013!GO:0019695;choline metabolic process;0.0065005020284588;218865!GO:0042439;ethanolamine and derivative metabolic process;0.0114689602854353;218865!GO:0009374;biotin binding;0.0114689602854353;18563!GO:0032787;monocarboxylic acid metabolic process;0.013096251318891;18563,19013!GO:0005743;mitochondrial inner membrane;0.0142120590508497;18563,218865!GO:0019866;organelle inner membrane;0.0142120590508497;18563,218865!GO:0031966;mitochondrial membrane;0.0142120590508497;18563,218865!GO:0044262;cellular carbohydrate metabolic process;0.0142120590508497;18563,19013!GO:0019217;regulation of fatty acid metabolic process;0.0142120590508497;19013!GO:0016885;ligase activity, forming carbon-carbon bonds;0.0142120590508497;18563!GO:0005740;mitochondrial envelope;0.0148516707081126;18563,218865!GO:0017153;sodium:dicarboxylate symporter activity;0.0149912985343832;114644!GO:0006835;dicarboxylic acid transport;0.0173968011642717;114644!GO:0005310;dicarboxylic acid transmembrane transporter activity;0.0173968011642717;114644!GO:0044429;mitochondrial part;0.0177160223997982;18563,218865!GO:0005975;carbohydrate metabolic process;0.0205855343660068;18563,19013!GO:0031975;envelope;0.0224742366795592;18563,218865!GO:0031967;organelle envelope;0.0224742366795592;18563,218865!GO:0006094;gluconeogenesis;0.0250743263206327;18563!GO:0015296;anion:cation symporter activity;0.0256832636280242;114644!GO:0005343;organic acid:sodium symporter activity;0.0256832636280242;114644!GO:0019216;regulation of lipid metabolic process;0.0256832636280242;19013!GO:0006090;pyruvate metabolic process;0.0276135025934446;18563!GO:0019319;hexose biosynthetic process;0.0294410289118389;18563!GO:0042401;biogenic amine biosynthetic process;0.0296530734806422;218865!GO:0046165;alcohol biosynthetic process;0.0296530734806422;18563!GO:0046364;monosaccharide biosynthetic process;0.0296530734806422;18563!GO:0044255;cellular lipid metabolic process;0.030747846169631;18563,19013!GO:0042398;amino acid derivative biosynthetic process;0.0311821039025154;218865!GO:0031090;organelle membrane;0.0311821039025154;18563,218865!GO:0006629;lipid metabolic process;0.0376562959052965;18563,19013!GO:0015370;solute:sodium symporter activity;0.0422184080370688;114644!GO:0003707;steroid hormone receptor activity;0.0485086249414863;19013!GO:0004879;ligand-dependent nuclear receptor 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| |||
|coexpression_dpi_cluster_scores_median=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.506657285314008,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.218555320865808,0.0862481039219708,0,0.0210011038741394,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.647548782992212,1.04920134876188,0.903965374234856,0.945073302214452,0.861676349947304,0.792142497240364,0,0,0,0,0,0,0,0,0,0,1.03421978120145,0,0.112901225419538,0,0,0.417356831753126,0.399193553037224,0.360494157887452,0.440804001341851,0.898805184016489,0.520298732990385,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0421182837367051,0.210060181764701,0,0,0,0,0,0.162000848159969,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0797901069290224,0.0872055405749939,0.290285790444849,0,0.123654991486488,0.0982055462128806,0.145480126286698,0,0,0,0,0,0.163457778354187,0.366612760987425,0.666993424784522,0.850765663252616,0.988493466384598,1.67418032260446,1.37802655558828,1.34006380789294,1.50309976864294,0.980956587774197,0.0670132089181356,0.25193883318552,0.32721800839367,0.535840943218784,1.18268428856877,1.56101777865855,1.72722149385164,1.64402715262851,1.61078154540167,1.49403380118932,1.70003363510312,1.50367807371198,0.939024155482642,0.964011945266222,0.96034678021343,0,0,0,0,0,0,0.169112038294096,0,0,0,0,0.123108665731713,0.0691813633419548,0.0107077170072103,0,0,0,0.10582914506561,0,0,0,0.0913200690696925,0,0,0,0,0,0,0,0,0,0,0.108524491213051,0.276537171471042,0,0.123832128606708,0,0,0,0,0,0,0.0998284739419172,0,0.1324189587654,0,0,0,0,0,0,0,0,0,0,0,0.14527379348779,0.313690168028553,0,0.0883423998797865,0,0,0,0.0660055475634404,0.111087966368681,0,0,0,0.0737896374598673,0,0,0,0,0,0,0,0,0,0.0445418537893845,0,0.174697384122552,0.395065530119756,0.815430404109401,0.100975358632432,0.0139053917903895,0,0,0,0,0,0,0,0,0.36211359164562,0,0,0.0517473144166473,0,0,0,0,0,0,0,0,0,0,0,0,0.0398944891531444,0,0,0,0,0,0,0.201246522626106,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0684580848992459,0.295000909831166,0.211878289366281,0.540874603589178,0.613995455612163,0.69771981334067,0.739799236415186,0.680377052869876,0.775907831452666,0.695582635516603,0.717160018247628,0.696317890281736,0.695748419302245,0.52910534052119,0.741898849485221,0.65053733412937,0.540644181036986,0.627199506642635,0.708797326245089,0.690289813893717,0.666019738288511,0.591835444748819,0.734250886457156,0.76514922521009,0.786892136336876,0.632204522042256,0.716831682248083,0.494343199373666,0.658874407016456,0.65764484689957,0.421097641412443,0.62876416846111,0.719658164608095,0,0.794678253004593,0.94128070561822,0.0760168881589905,0.220572027003917,0.188495428553301 | |||
|gostat_on_MCL_coexpression=GO:0006066;alcohol metabolic process;0.00410307789521319;18563,218865,19013!GO:0019752;carboxylic acid metabolic process;0.00410307789521319;18563,218865,19013!GO:0006082;organic acid metabolic process;0.00410307789521319;18563,218865,19013!GO:0008812;choline dehydrogenase activity;0.00410307789521319;218865!GO:0004736;pyruvate carboxylase activity;0.00410307789521319;18563!GO:0031455;glycine betaine metabolic process;0.00410307789521319;218865!GO:0006578;betaine biosynthetic process;0.00410307789521319;218865!GO:0031456;glycine betaine biosynthetic process;0.00410307789521319;218865!GO:0019285;glycine betaine biosynthetic process from choline;0.00410307789521319;218865!GO:0006577;betaine metabolic process;0.00410307789521319;218865!GO:0015362;high affinity sodium:dicarboxylate symporter activity;0.00410307789521319;114644!GO:0006006;glucose metabolic process;0.00410307789521319;18563,19013!GO:0019318;hexose metabolic process;0.0065005020284588;18563,19013!GO:0005996;monosaccharide metabolic process;0.0065005020284588;18563,19013!GO:0019695;choline metabolic process;0.0065005020284588;218865!GO:0042439;ethanolamine and derivative metabolic process;0.0114689602854353;218865!GO:0009374;biotin binding;0.0114689602854353;18563!GO:0032787;monocarboxylic acid metabolic process;0.013096251318891;18563,19013!GO:0005743;mitochondrial inner membrane;0.0142120590508497;18563,218865!GO:0019866;organelle inner membrane;0.0142120590508497;18563,218865!GO:0031966;mitochondrial membrane;0.0142120590508497;18563,218865!GO:0044262;cellular carbohydrate metabolic process;0.0142120590508497;18563,19013!GO:0019217;regulation of fatty acid metabolic process;0.0142120590508497;19013!GO:0016885;ligase activity, forming carbon-carbon bonds;0.0142120590508497;18563!GO:0005740;mitochondrial envelope;0.0148516707081126;18563,218865!GO:0017153;sodium:dicarboxylate symporter activity;0.0149912985343832;114644!GO:0006835;dicarboxylic acid transport;0.0173968011642717;114644!GO:0005310;dicarboxylic acid transmembrane transporter activity;0.0173968011642717;114644!GO:0044429;mitochondrial part;0.0177160223997982;18563,218865!GO:0005975;carbohydrate metabolic process;0.0205855343660068;18563,19013!GO:0031975;envelope;0.0224742366795592;18563,218865!GO:0031967;organelle envelope;0.0224742366795592;18563,218865!GO:0006094;gluconeogenesis;0.0250743263206327;18563!GO:0015296;anion:cation symporter activity;0.0256832636280242;114644!GO:0005343;organic acid:sodium symporter activity;0.0256832636280242;114644!GO:0019216;regulation of lipid metabolic process;0.0256832636280242;19013!GO:0006090;pyruvate metabolic process;0.0276135025934446;18563!GO:0019319;hexose biosynthetic process;0.0294410289118389;18563!GO:0042401;biogenic amine biosynthetic process;0.0296530734806422;218865!GO:0046165;alcohol biosynthetic process;0.0296530734806422;18563!GO:0046364;monosaccharide biosynthetic process;0.0296530734806422;18563!GO:0044255;cellular lipid metabolic process;0.030747846169631;18563,19013!GO:0042398;amino acid derivative biosynthetic process;0.0311821039025154;218865!GO:0031090;organelle membrane;0.0311821039025154;18563,218865!GO:0006629;lipid metabolic process;0.0376562959052965;18563,19013!GO:0015370;solute:sodium symporter activity;0.0422184080370688;114644!GO:0003707;steroid hormone receptor activity;0.0485086249414863;19013!GO:0004879;ligand-dependent nuclear receptor activity;0.0485086249414863;19013! | |||
}} |
Latest revision as of 15:40, 17 September 2013
Phase1 CAGE Peaks
Short description | |
---|---|
Mm9::chr11:46512321..46512337,- | p4@Timd2 |
Mm9::chr11:55031211..55031234,+ | p@chr11:55031211..55031234 + |
Mm9::chr14:30822115..30822130,+ | p5@Chdh |
Mm9::chr15:85602581..85602598,+ | p8@Ppara |
Mm9::chr16:23029153..23029179,- | p1@Kng2 |
Mm9::chr16:23029188..23029211,- | p2@Kng2 |
Mm9::chr19:4594312..4594332,+ | p5@Pcx |
Mm9::chr19:4594337..4594361,+ | p6@Pcx |
Mm9::chr19:4594363..4594394,+ | p3@Pcx |
Mm9::chr19:4594398..4594422,+ | p4@Pcx |
Mm9::chr2:165298687..165298702,- | p1@Slc13a3 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0006066 | alcohol metabolic process | 0.00410307789521319 |
GO:0019752 | carboxylic acid metabolic process | 0.00410307789521319 |
GO:0006082 | organic acid metabolic process | 0.00410307789521319 |
GO:0008812 | choline dehydrogenase activity | 0.00410307789521319 |
GO:0004736 | pyruvate carboxylase activity | 0.00410307789521319 |
GO:0031455 | glycine betaine metabolic process | 0.00410307789521319 |
GO:0006578 | betaine biosynthetic process | 0.00410307789521319 |
GO:0031456 | glycine betaine biosynthetic process | 0.00410307789521319 |
GO:0019285 | glycine betaine biosynthetic process from choline | 0.00410307789521319 |
GO:0006577 | betaine metabolic process | 0.00410307789521319 |
GO:0015362 | high affinity sodium:dicarboxylate symporter activity | 0.00410307789521319 |
GO:0006006 | glucose metabolic process | 0.00410307789521319 |
GO:0019318 | hexose metabolic process | 0.0065005020284588 |
GO:0005996 | monosaccharide metabolic process | 0.0065005020284588 |
GO:0019695 | choline metabolic process | 0.0065005020284588 |
GO:0042439 | ethanolamine and derivative metabolic process | 0.0114689602854353 |
GO:0009374 | biotin binding | 0.0114689602854353 |
GO:0032787 | monocarboxylic acid metabolic process | 0.013096251318891 |
GO:0005743 | mitochondrial inner membrane | 0.0142120590508497 |
GO:0019866 | organelle inner membrane | 0.0142120590508497 |
GO:0031966 | mitochondrial membrane | 0.0142120590508497 |
GO:0044262 | cellular carbohydrate metabolic process | 0.0142120590508497 |
GO:0019217 | regulation of fatty acid metabolic process | 0.0142120590508497 |
GO:0016885 | ligase activity, forming carbon-carbon bonds | 0.0142120590508497 |
GO:0005740 | mitochondrial envelope | 0.0148516707081126 |
GO:0017153 | sodium:dicarboxylate symporter activity | 0.0149912985343832 |
GO:0006835 | dicarboxylic acid transport | 0.0173968011642717 |
GO:0005310 | dicarboxylic acid transmembrane transporter activity | 0.0173968011642717 |
GO:0044429 | mitochondrial part | 0.0177160223997982 |
GO:0005975 | carbohydrate metabolic process | 0.0205855343660068 |
GO:0031975 | envelope | 0.0224742366795592 |
GO:0031967 | organelle envelope | 0.0224742366795592 |
GO:0006094 | gluconeogenesis | 0.0250743263206327 |
GO:0015296 | anion:cation symporter activity | 0.0256832636280242 |
GO:0005343 | organic acid:sodium symporter activity | 0.0256832636280242 |
GO:0019216 | regulation of lipid metabolic process | 0.0256832636280242 |
GO:0006090 | pyruvate metabolic process | 0.0276135025934446 |
GO:0019319 | hexose biosynthetic process | 0.0294410289118389 |
GO:0042401 | biogenic amine biosynthetic process | 0.0296530734806422 |
GO:0046165 | alcohol biosynthetic process | 0.0296530734806422 |
GO:0046364 | monosaccharide biosynthetic process | 0.0296530734806422 |
GO:0044255 | cellular lipid metabolic process | 0.030747846169631 |
GO:0042398 | amino acid derivative biosynthetic process | 0.0311821039025154 |
GO:0031090 | organelle membrane | 0.0311821039025154 |
GO:0006629 | lipid metabolic process | 0.0376562959052965 |
GO:0015370 | solute:sodium symporter activity | 0.0422184080370688 |
GO:0003707 | steroid hormone receptor activity | 0.0485086249414863 |
GO:0004879 | ligand-dependent nuclear receptor activity | 0.0485086249414863 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
abdomen element | 4.58e-19 | 49 |
abdominal segment element | 4.58e-19 | 49 |
abdominal segment of trunk | 4.58e-19 | 49 |
abdomen | 4.58e-19 | 49 |
liver | 3.02e-17 | 22 |
epithelial sac | 3.02e-17 | 22 |
digestive gland | 3.02e-17 | 22 |
epithelium of foregut-midgut junction | 3.02e-17 | 22 |
anatomical boundary | 3.02e-17 | 22 |
hepatobiliary system | 3.02e-17 | 22 |
foregut-midgut junction | 3.02e-17 | 22 |
hepatic diverticulum | 3.02e-17 | 22 |
liver primordium | 3.02e-17 | 22 |
septum transversum | 3.02e-17 | 22 |
liver bud | 3.02e-17 | 22 |
digestive tract diverticulum | 4.01e-16 | 23 |
sac | 4.01e-16 | 23 |
exocrine gland | 2.29e-15 | 25 |
exocrine system | 2.29e-15 | 25 |
subdivision of trunk | 2.00e-13 | 66 |
mesenchyme | 6.33e-12 | 61 |
entire embryonic mesenchyme | 6.33e-12 | 61 |
trunk region element | 3.62e-10 | 79 |
trunk mesenchyme | 2.76e-09 | 45 |
trunk | 2.46e-07 | 90 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 0.570495 |
MA0004.1 | 0.330313 |
MA0006.1 | 0.186435 |
MA0007.1 | 0.316976 |
MA0009.1 | 1.75966 |
MA0014.1 | 0.44164 |
MA0017.1 | 1.76941 |
MA0019.1 | 0.567591 |
MA0024.1 | 0.70077 |
MA0025.1 | 0.971686 |
MA0027.1 | 2.37948 |
MA0028.1 | 0.194782 |
MA0029.1 | 0.679737 |
MA0030.1 | 0.686088 |
MA0031.1 | 0.651724 |
MA0038.1 | 0.462726 |
MA0040.1 | 0.755433 |
MA0041.1 | 0.263922 |
MA0042.1 | 0.252679 |
MA0043.1 | 0.837621 |
MA0046.1 | 1.83192 |
MA0048.1 | 0.440822 |
MA0050.1 | 0.95731 |
MA0051.1 | 0.471092 |
MA0052.1 | 0.76328 |
MA0055.1 | 1.79839 |
MA0056.1 | 0 |
MA0057.1 | 0.181039 |
MA0058.1 | 0.246908 |
MA0059.1 | 0.257372 |
MA0060.1 | 0.789184 |
MA0061.1 | 0.147394 |
MA0063.1 | 0 |
MA0066.1 | 0.452472 |
MA0067.1 | 1.08124 |
MA0068.1 | 0.187364 |
MA0069.1 | 0.76361 |
MA0070.1 | 0.75417 |
MA0071.1 | 0.955636 |
MA0072.1 | 0.745922 |
MA0073.1 | 0.0212456 |
MA0074.1 | 0.419185 |
MA0076.1 | 0.223625 |
MA0077.1 | 0.724865 |
MA0078.1 | 1.25398 |
MA0081.1 | 0.277253 |
MA0083.1 | 0.836845 |
MA0084.1 | 1.4063 |
MA0087.1 | 0.794721 |
MA0088.1 | 0.12124 |
MA0089.1 | 0 |
MA0090.1 | 0.299987 |
MA0091.1 | 0.342071 |
MA0092.1 | 0.300264 |
MA0093.1 | 0.58345 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.408523 |
MA0101.1 | 0.265031 |
MA0103.1 | 0.216742 |
MA0105.1 | 0.0759118 |
MA0106.1 | 0.509454 |
MA0107.1 | 0.211681 |
MA0108.2 | 0.589413 |
MA0109.1 | 0 |
MA0111.1 | 0.312463 |
MA0113.1 | 0.482899 |
MA0114.1 | 2.0321 |
MA0115.1 | 0.84036 |
MA0116.1 | 1.04399 |
MA0117.1 | 0.808813 |
MA0119.1 | 0.733279 |
MA0122.1 | 0.828211 |
MA0124.1 | 1.02871 |
MA0125.1 | 0.955734 |
MA0130.1 | 0 |
MA0131.1 | 0.563262 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 0.873285 |
MA0136.1 | 0.437601 |
MA0139.1 | 0.338099 |
MA0140.1 | 0.408417 |
MA0141.1 | 2.67467 |
MA0142.1 | 0.63775 |
MA0143.1 | 1.24578 |
MA0144.1 | 0.147954 |
MA0145.1 | 0.3137 |
MA0146.1 | 1.06665 |
MA0147.1 | 0.157258 |
MA0148.1 | 0.912216 |
MA0149.1 | 0.269772 |
MA0062.2 | 0.0791588 |
MA0035.2 | 0.412747 |
MA0039.2 | 0.0156442 |
MA0138.2 | 0.555696 |
MA0002.2 | 0.105469 |
MA0137.2 | 0.230686 |
MA0104.2 | 0.369356 |
MA0047.2 | 0.46201 |
MA0112.2 | 0.313687 |
MA0065.2 | 1.30208 |
MA0150.1 | 0.316876 |
MA0151.1 | 0 |
MA0152.1 | 0.46211 |
MA0153.1 | 2.06069 |
MA0154.1 | 0.195907 |
MA0155.1 | 0.0394399 |
MA0156.1 | 0.222905 |
MA0157.1 | 0.606944 |
MA0158.1 | 0 |
MA0159.1 | 0.165031 |
MA0160.1 | 0.347545 |
MA0161.1 | 0 |
MA0162.1 | 0.00661648 |
MA0163.1 | 0.820388 |
MA0164.1 | 0.437937 |
MA0080.2 | 0.212408 |
MA0018.2 | 0.446948 |
MA0099.2 | 0.549696 |
MA0079.2 | 0.150907 |
MA0102.2 | 1.45844 |
MA0258.1 | 1.34967 |
MA0259.1 | 0.455671 |
MA0442.1 | 0 |