MCL coexpression mm9:1225: Difference between revisions
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{{MCL_coexpression_mm9 | 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regulation of isotype switching to IgE isotypes;0.0151579902491918;20852!GO:0002829;negative regulation of T-helper 2 type immune response;0.0151579902491918;20852!GO:0002828;regulation of T-helper 2 type immune response;0.0151579902491918;20852!GO:0045944;positive regulation of transcription from RNA polymerase II promoter;0.0151579902491918;20852,21937!GO:0048289;isotype switching to IgE isotypes;0.0151579902491918;20852!GO:0043120;tumor necrosis factor binding;0.0151579902491918;21937!GO:0048293;regulation of isotype switching to IgE isotypes;0.0151579902491918;20852!GO:0005031;tumor necrosis factor receptor activity;0.0151579902491918;21937!GO:0045893;positive regulation of transcription, DNA-dependent;0.0151579902491918;20852,21937!GO:0002820;negative regulation of adaptive immune response;0.0151579902491918;20852!GO:0005035;death receptor activity;0.0151579902491918;21937!GO:0002823;negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0151579902491918;20852!GO:0050777;negative regulation of immune response;0.0151579902491918;20852!GO:0002683;negative regulation of immune system process;0.0151579902491918;20852!GO:0042092;T-helper 2 type immune response;0.0151579902491918;20852!GO:0045941;positive regulation of transcription;0.0151579902491918;20852,21937!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0151579902491918;20852,21937!GO:0045830;positive regulation of isotype switching;0.0194908236070853;20852!GO:0031325;positive regulation of cellular metabolic process;0.0195423438037034;20852,21937!GO:0009893;positive regulation of metabolic process;0.0195423438037034;20852,21937!GO:0043283;biopolymer metabolic process;0.0195423438037034;20852,14284,211770,21937!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.0195423438037034;20852,21937!GO:0045191;regulation of isotype switching;0.0195423438037034;20852!GO:0006693;prostaglandin metabolic process;0.0195423438037034;21937!GO:0006692;prostanoid metabolic process;0.0195423438037034;21937!GO:0006366;transcription from RNA polymerase II promoter;0.0195423438037034;20852,21937!GO:0043565;sequence-specific DNA binding;0.0195423438037034;20852,14284!GO:0006355;regulation of transcription, DNA-dependent;0.0195423438037034;20852,14284,21937!GO:0006351;transcription, DNA-dependent;0.0195423438037034;20852,14284,21937!GO:0032774;RNA biosynthetic process;0.0195423438037034;20852,14284,21937!GO:0050729;positive regulation of inflammatory response;0.0195423438037034;21937!GO:0031349;positive regulation of defense response;0.0195423438037034;21937!GO:0045449;regulation of transcription;0.0195423438037034;20852,14284,21937!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0195423438037034;20852,14284,21937!GO:0004860;protein kinase inhibitor activity;0.0195423438037034;211770!GO:0006350;transcription;0.0195423438037034;20852,14284,21937!GO:0002208;somatic diversification of immunoglobulins during immune response;0.0195423438037034;20852!GO:0002204;somatic recombination of immunoglobulin genes during immune response;0.0195423438037034;20852!GO:0045190;isotype switching;0.0195423438037034;20852!GO:0002381;immunoglobulin production during immune response;0.0195423438037034;20852!GO:0019210;kinase inhibitor activity;0.0195423438037034;211770!GO:0002819;regulation of adaptive immune response;0.0195423438037034;20852!GO:0002822;regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains.;0.0195423438037034;20852!GO:0010468;regulation of gene expression;0.0195423438037034;20852,14284,21937!GO:0031323;regulation of cellular metabolic process;0.0208470082702882;20852,14284,21937!GO:0050871;positive regulation of B cell activation;0.0208470082702882;20852!GO:0016447;somatic recombination of immunoglobulin gene segments;0.0208470082702882;20852!GO:0019222;regulation of metabolic process;0.0208470082702882;20852,14284,21937!GO:0031347;regulation of defense response;0.0208470082702882;21937!GO:0051241;negative regulation of multicellular organismal process;0.0208470082702882;20852!GO:0050727;regulation of inflammatory response;0.0208470082702882;21937!GO:0016444;somatic cell DNA recombination;0.0208470082702882;20852!GO:0002562;somatic diversification of immune receptors via germline recombination within a single locus;0.0208470082702882;20852!GO:0016070;RNA metabolic process;0.0208470082702882;20852,14284,21937!GO:0006690;icosanoid metabolic process;0.0208470082702882;21937!GO:0016445;somatic diversification of immunoglobulins;0.0208470082702882;20852!GO:0002200;somatic diversification of immune receptors;0.0218430977084959;20852!GO:0043170;macromolecule metabolic process;0.0222453518230858;20852,14284,211770,21937!GO:0050864;regulation of B cell activation;0.0243899157232587;20852!GO:0002377;immunoglobulin production;0.0252756617130364;20852!GO:0002440;production of molecular mediator of immune response;0.0253148365305417;20852!GO:0048522;positive regulation of cellular process;0.0253148365305417;20852,21937!GO:0048583;regulation of response to stimulus;0.0271470582401027;21937!GO:0019221;cytokine and chemokine mediated signaling pathway;0.0273279768087273;21937!GO:0010467;gene expression;0.0295513593912224;20852,14284,21937!GO:0003700;transcription factor activity;0.0295513593912224;20852,14284!GO:0048518;positive regulation of biological process;0.0309642625493989;20852,21937!GO:0044238;primary metabolic process;0.0336469501789967;20852,14284,211770,21937!GO:0044237;cellular metabolic process;0.0336585119279058;20852,14284,211770,21937!GO:0051251;positive regulation of lymphocyte activation;0.0338248111422986;20852!GO:0019887;protein kinase regulator activity;0.0344361317682002;211770!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0356074807768266;20852,14284,21937!GO:0019955;cytokine binding;0.0356074807768266;21937!GO:0016064;immunoglobulin mediated immune response;0.0366900650795972;20852!GO:0019724;B cell mediated immunity;0.0367149999362538;20852!GO:0006310;DNA recombination;0.0372632124910298;20852!GO:0019207;kinase regulator activity;0.0372632124910298;211770!GO:0050794;regulation of cellular process;0.0404470684666517;20852,14284,21937!GO:0051249;regulation of lymphocyte activation;0.0407069757311571;20852!GO:0042113;B cell activation;0.0411267233716689;20852!GO:0050865;regulation of cell activation;0.0411267233716689;20852!GO:0002250;adaptive immune response;0.0415255534530609;20852!GO:0002460;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0415255534530609;20852!GO:0002449;lymphocyte mediated immunity;0.0424038110968864;20852!GO:0002443;leukocyte mediated immunity;0.0450674053215862;20852!GO:0050789;regulation of biological process;0.0493197986807879;20852,14284,21937!GO:0050776;regulation of immune response;0.0493197986807879;20852!GO:0002682;regulation of immune system process;0.0496297266270087;20852!|ontology_enrichment_celltype=|ontology_enrichment_disease=|ontology_enrichment_uberon=UBERON:0005409!1.37e-08!47;UBERON:0000160!2.12e-08!31;UBERON:0004119!2.97e-08!118;UBERON:0000925!2.97e-08!118;UBERON:0006595!2.97e-08!118;UBERON:0001007!7.50e-08!116;UBERON:0001555!7.50e-08!116;UBERON:0007026!7.50e-08!116;UBERON:0004921!3.21e-07!114;UBERON:0000344!4.89e-07!15|tfbs_overrepresentation_for_novel_motifs=0.491922,1.73744,0.464605,0.535892,0.346849,0.550971,0.645383,0.247459,0.257202,0.594834,0.599767,0.632897,0.247704,0.6581,0.364314,0,0.856992,0.338549,0.232269,0.442204,0.426133,0.35122,0.657163,0.345236,0.472505,0.686615,0.223823,0.572827,0.394364,1.0231,0.558142,0.960397,0.336199,0.204204,0.364821,0.607065,1.56842,0.629145,0.303703,0.27383,0.342638,0.56353,0.0995018,0.366415,0.368882,0.524258,1.82546,1.43855,0.0835644,0.397446,0.839084,0.714419,0.517905,1.10437,1.12205,0.66551,0.406788,1.50238,0.614918,0.663395,0.939962,0.724164,0.269393,0.827522,0.677043,0.869046,1.2599,1.61148,0.935192,1.46355,0.444872,0.70565,3.09546,1.156,0.208101,0.57254,0.589776,0.763395,0.922432,1.10012,0.708505,0.874787,0.722675,0.240896,2.36544,0.768392,2.30747,0.534643,0.780154,1.77427,1.33021,1.04409,0.973447,0.35304,1.47187,0.281222,0.244935,0.976308,0.775372,0.160254,0.326561,0.960112,1.08669,0.839694,0.838613,0.563071,0.8998,0.585058,0.435642,1.09461,0.484547,1.0885,0.431734,0.605144,1.33732,0.340765,1.35637,0.53982,0.858327,0.322606,1.16147,0.805995,0.688501,0.762461,1.39185,0.926209,0.65384,0.966541,1.25836,0.356163,1.06946,0.52828,1.2285,0.679647,1.35909,0.347287,1.25097,0.564999,1.30952,2.14327,1.74232,1.26465,0.700956,0.971067,0.831964,0.564002,0.778321,2.10357,0.503174,0.348692,0.540361,1.63283,1.10596,0.287383,0.678689,1.18867,0.71546,0.376898,0.48935,0.500417,1.31911,1.03816,0.926663,1.21135,0.82857,0.671017,0.86867,0.63125,0.5667|tfbs_overrepresentation_jaspar=MA0003.1;0.276983,MA0004.1;0.536396,MA0006.1;0.945134,MA0007.1;0.52077,MA0009.1;0.987341,MA0014.1;0.558098,MA0017.1;1.00628,MA0019.1;0.800946,MA0024.1;2.16928,MA0025.1;1.22395,MA0027.1;2.64231,MA0028.1;0.969171,MA0029.1;0.920529,MA0030.1;0.927235,MA0031.1;0.890871,MA0038.1;0.686534,MA0040.1;1.00009,MA0041.1;0.457338,MA0042.1;0.443591,MA0043.1;1.08567,MA0046.1;1.02391,MA0048.1;0.161427,MA0050.1;0.57678,MA0051.1;0.695779,MA0052.1;1.00829,MA0055.1;0.0585191,MA0056.1;0,MA0057.1;0.895081,MA0058.1;0.436487,MA0059.1;1.14076,MA0060.1;0.275911,MA0061.1;1.49922,MA0063.1;0,MA0066.1;0.675169,MA0067.1;1.33603,MA0068.1;0.153907,MA0069.1;1.00864,MA0070.1;0.998765,MA0071.1;0.575909,MA0072.1;0.990133,MA0073.1;0.753052,MA0074.1;0.638014,MA0076.1;1.04996,MA0077.1;0.968053,MA0078.1;0.729877,MA0081.1;0.473489,MA0083.1;1.08487,MA0084.1;1.66561,MA0087.1;1.04109,MA0088.1;0.358337,MA0089.1;0,MA0090.1;0.500693,MA0091.1;0.55008,MA0092.1;0.501022,MA0093.1;0.988233,MA0095.1;0,MA0098.1;0,MA0100.1;0.626021,MA0101.1;0.458688,MA0103.1;0.398766,MA0105.1;2.43957,MA0106.1;0.737893,MA0107.1;0.392331,MA0108.2;0.824407,MA0109.1;0,MA0111.1;0.515457,MA0113.1;0.708789,MA0114.1;0.822296,MA0115.1;1.08851,MA0116.1;0.359483,MA0117.1;1.05576,MA0119.1;0.459301,MA0122.1;1.07591,MA0124.1;1.28237,MA0125.1;1.20757,MA0130.1;0,MA0131.1;0.796279,MA0132.1;0,MA0133.1;0,MA0135.1;1.1226,MA0136.1;0.658622,MA0139.1;0.243463,MA0140.1;0.625902,MA0141.1;1.07584,MA0142.1;0.876028,MA0143.1;0.725672,MA0144.1;0.307873,MA0145.1;0.119202,MA0146.1;0.153598,MA0147.1;0.858298,MA0148.1;0.553294,MA0149.1;0.464445,MA0062.2;1.11803,MA0035.2;0.630778,MA0039.2;0.181031,MA0138.2;0.788113,MA0002.2;0.246463,MA0137.2;0.416331,MA0104.2;0.723439,MA0047.2;0.685741,MA0112.2;0.37938,MA0065.2;0.380324,MA0150.1;0.520653,MA0151.1;0,MA0152.1;0.685852,MA0153.1;1.13945,MA0154.1;0.159217,MA0155.1;0.132921,MA0156.1;1.04798,MA0157.1;0.843181,MA0158.1;0,MA0159.1;0.331229,MA0160.1;0.556423,MA0161.1;0,MA0162.1;0.70356,MA0163.1;1.03138,MA0164.1;0.658997,MA0080.2;0.393257,MA0018.2;0.669032,MA0099.2;0.781628,MA0079.2;0.730639,MA0102.2;1.7182,MA0258.1;0.290587,MA0259.1;1.5079,MA0442.1;0}} 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|gostat_on_MCL_coexpression=GO:0048295;positive regulation of isotype switching to IgE isotypes;0.0151579902491918;20852!GO:0002829;negative regulation of T-helper 2 type immune response;0.0151579902491918;20852!GO:0002828;regulation of T-helper 2 type immune response;0.0151579902491918;20852!GO:0045944;positive regulation of transcription from RNA polymerase II promoter;0.0151579902491918;20852,21937!GO:0048289;isotype switching to IgE isotypes;0.0151579902491918;20852!GO:0043120;tumor necrosis factor binding;0.0151579902491918;21937!GO:0048293;regulation of isotype switching to IgE isotypes;0.0151579902491918;20852!GO:0005031;tumor necrosis factor receptor activity;0.0151579902491918;21937!GO:0045893;positive regulation of transcription, DNA-dependent;0.0151579902491918;20852,21937!GO:0002820;negative regulation of adaptive immune response;0.0151579902491918;20852!GO:0005035;death receptor activity;0.0151579902491918;21937!GO:0002823;negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0151579902491918;20852!GO:0050777;negative regulation of immune response;0.0151579902491918;20852!GO:0002683;negative regulation of immune system process;0.0151579902491918;20852!GO:0042092;T-helper 2 type immune response;0.0151579902491918;20852!GO:0045941;positive regulation of transcription;0.0151579902491918;20852,21937!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0151579902491918;20852,21937!GO:0045830;positive regulation of isotype switching;0.0194908236070853;20852!GO:0031325;positive regulation of cellular metabolic process;0.0195423438037034;20852,21937!GO:0009893;positive regulation of metabolic process;0.0195423438037034;20852,21937!GO:0043283;biopolymer metabolic process;0.0195423438037034;20852,14284,211770,21937!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.0195423438037034;20852,21937!GO:0045191;regulation of isotype switching;0.0195423438037034;20852!GO:0006693;prostaglandin metabolic process;0.0195423438037034;21937!GO:0006692;prostanoid metabolic process;0.0195423438037034;21937!GO:0006366;transcription from RNA polymerase II promoter;0.0195423438037034;20852,21937!GO:0043565;sequence-specific DNA binding;0.0195423438037034;20852,14284!GO:0006355;regulation of transcription, DNA-dependent;0.0195423438037034;20852,14284,21937!GO:0006351;transcription, DNA-dependent;0.0195423438037034;20852,14284,21937!GO:0032774;RNA biosynthetic process;0.0195423438037034;20852,14284,21937!GO:0050729;positive regulation of inflammatory response;0.0195423438037034;21937!GO:0031349;positive regulation of defense response;0.0195423438037034;21937!GO:0045449;regulation of transcription;0.0195423438037034;20852,14284,21937!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0195423438037034;20852,14284,21937!GO:0004860;protein kinase inhibitor activity;0.0195423438037034;211770!GO:0006350;transcription;0.0195423438037034;20852,14284,21937!GO:0002208;somatic diversification of immunoglobulins during immune response;0.0195423438037034;20852!GO:0002204;somatic recombination of immunoglobulin genes during immune response;0.0195423438037034;20852!GO:0045190;isotype switching;0.0195423438037034;20852!GO:0002381;immunoglobulin production during immune response;0.0195423438037034;20852!GO:0019210;kinase inhibitor activity;0.0195423438037034;211770!GO:0002819;regulation of adaptive immune response;0.0195423438037034;20852!GO:0002822;regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains.;0.0195423438037034;20852!GO:0010468;regulation of gene expression;0.0195423438037034;20852,14284,21937!GO:0031323;regulation of cellular metabolic process;0.0208470082702882;20852,14284,21937!GO:0050871;positive regulation of B cell activation;0.0208470082702882;20852!GO:0016447;somatic recombination of immunoglobulin gene segments;0.0208470082702882;20852!GO:0019222;regulation of metabolic process;0.0208470082702882;20852,14284,21937!GO:0031347;regulation of defense response;0.0208470082702882;21937!GO:0051241;negative regulation of multicellular organismal process;0.0208470082702882;20852!GO:0050727;regulation of inflammatory response;0.0208470082702882;21937!GO:0016444;somatic cell DNA recombination;0.0208470082702882;20852!GO:0002562;somatic diversification of immune receptors via germline recombination within a single locus;0.0208470082702882;20852!GO:0016070;RNA metabolic process;0.0208470082702882;20852,14284,21937!GO:0006690;icosanoid metabolic process;0.0208470082702882;21937!GO:0016445;somatic diversification of immunoglobulins;0.0208470082702882;20852!GO:0002200;somatic diversification of immune receptors;0.0218430977084959;20852!GO:0043170;macromolecule metabolic process;0.0222453518230858;20852,14284,211770,21937!GO:0050864;regulation of B cell activation;0.0243899157232587;20852!GO:0002377;immunoglobulin production;0.0252756617130364;20852!GO:0002440;production of molecular mediator of immune response;0.0253148365305417;20852!GO:0048522;positive regulation of cellular process;0.0253148365305417;20852,21937!GO:0048583;regulation of response to stimulus;0.0271470582401027;21937!GO:0019221;cytokine and chemokine mediated signaling pathway;0.0273279768087273;21937!GO:0010467;gene expression;0.0295513593912224;20852,14284,21937!GO:0003700;transcription factor activity;0.0295513593912224;20852,14284!GO:0048518;positive regulation of biological process;0.0309642625493989;20852,21937!GO:0044238;primary metabolic process;0.0336469501789967;20852,14284,211770,21937!GO:0044237;cellular metabolic process;0.0336585119279058;20852,14284,211770,21937!GO:0051251;positive regulation of lymphocyte activation;0.0338248111422986;20852!GO:0019887;protein kinase regulator activity;0.0344361317682002;211770!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0356074807768266;20852,14284,21937!GO:0019955;cytokine binding;0.0356074807768266;21937!GO:0016064;immunoglobulin mediated immune response;0.0366900650795972;20852!GO:0019724;B cell mediated immunity;0.0367149999362538;20852!GO:0006310;DNA recombination;0.0372632124910298;20852!GO:0019207;kinase regulator activity;0.0372632124910298;211770!GO:0050794;regulation of cellular process;0.0404470684666517;20852,14284,21937!GO:0051249;regulation of lymphocyte activation;0.0407069757311571;20852!GO:0042113;B cell activation;0.0411267233716689;20852!GO:0050865;regulation of cell activation;0.0411267233716689;20852!GO:0002250;adaptive immune response;0.0415255534530609;20852!GO:0002460;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0415255534530609;20852!GO:0002449;lymphocyte mediated immunity;0.0424038110968864;20852!GO:0002443;leukocyte mediated immunity;0.0450674053215862;20852!GO:0050789;regulation of biological process;0.0493197986807879;20852,14284,21937!GO:0050776;regulation of immune response;0.0493197986807879;20852!GO:0002682;regulation of immune system process;0.0496297266270087;20852! | |||
|ontology_enrichment_celltype= | |||
|ontology_enrichment_disease= | |||
|ontology_enrichment_uberon=UBERON:0005409!1.37e-08!47;UBERON:0000160!2.12e-08!31;UBERON:0004119!2.97e-08!118;UBERON:0000925!2.97e-08!118;UBERON:0006595!2.97e-08!118;UBERON:0001007!7.50e-08!116;UBERON:0001555!7.50e-08!116;UBERON:0007026!7.50e-08!116;UBERON:0004921!3.21e-07!114;UBERON:0000344!4.89e-07!15 | |||
}} |
Latest revision as of 16:35, 17 September 2013
Phase1 CAGE Peaks
Short description | |
---|---|
Mm9::chr10:127080091..127080100,+ | p4@Stat6 |
Mm9::chr11:22760432..22760456,- | p3@B3gnt2 |
Mm9::chr15:59480199..59480242,+ | p1@Trib1 |
Mm9::chr5:32438831..32438878,+ | p1@Fosl2 |
Mm9::chr5:32438894..32438908,+ | p2@Fosl2 |
Mm9::chr6:125299825..125299838,+ | p4@Tnfrsf1a |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0048295 | positive regulation of isotype switching to IgE isotypes | 0.0151579902491918 |
GO:0002829 | negative regulation of T-helper 2 type immune response | 0.0151579902491918 |
GO:0002828 | regulation of T-helper 2 type immune response | 0.0151579902491918 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 0.0151579902491918 |
GO:0048289 | isotype switching to IgE isotypes | 0.0151579902491918 |
GO:0043120 | tumor necrosis factor binding | 0.0151579902491918 |
GO:0048293 | regulation of isotype switching to IgE isotypes | 0.0151579902491918 |
GO:0005031 | tumor necrosis factor receptor activity | 0.0151579902491918 |
GO:0045893 | positive regulation of transcription, DNA-dependent | 0.0151579902491918 |
GO:0002820 | negative regulation of adaptive immune response | 0.0151579902491918 |
GO:0005035 | death receptor activity | 0.0151579902491918 |
GO:0002823 | negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 0.0151579902491918 |
GO:0050777 | negative regulation of immune response | 0.0151579902491918 |
GO:0002683 | negative regulation of immune system process | 0.0151579902491918 |
GO:0042092 | T-helper 2 type immune response | 0.0151579902491918 |
GO:0045941 | positive regulation of transcription | 0.0151579902491918 |
GO:0045935 | positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 0.0151579902491918 |
GO:0045830 | positive regulation of isotype switching | 0.0194908236070853 |
GO:0031325 | positive regulation of cellular metabolic process | 0.0195423438037034 |
GO:0009893 | positive regulation of metabolic process | 0.0195423438037034 |
GO:0043283 | biopolymer metabolic process | 0.0195423438037034 |
GO:0006357 | regulation of transcription from RNA polymerase II promoter | 0.0195423438037034 |
GO:0045191 | regulation of isotype switching | 0.0195423438037034 |
GO:0006693 | prostaglandin metabolic process | 0.0195423438037034 |
GO:0006692 | prostanoid metabolic process | 0.0195423438037034 |
GO:0006366 | transcription from RNA polymerase II promoter | 0.0195423438037034 |
GO:0043565 | sequence-specific DNA binding | 0.0195423438037034 |
GO:0006355 | regulation of transcription, DNA-dependent | 0.0195423438037034 |
GO:0006351 | transcription, DNA-dependent | 0.0195423438037034 |
GO:0032774 | RNA biosynthetic process | 0.0195423438037034 |
GO:0050729 | positive regulation of inflammatory response | 0.0195423438037034 |
GO:0031349 | positive regulation of defense response | 0.0195423438037034 |
GO:0045449 | regulation of transcription | 0.0195423438037034 |
GO:0019219 | regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 0.0195423438037034 |
GO:0004860 | protein kinase inhibitor activity | 0.0195423438037034 |
GO:0006350 | transcription | 0.0195423438037034 |
GO:0002208 | somatic diversification of immunoglobulins during immune response | 0.0195423438037034 |
GO:0002204 | somatic recombination of immunoglobulin genes during immune response | 0.0195423438037034 |
GO:0045190 | isotype switching | 0.0195423438037034 |
GO:0002381 | immunoglobulin production during immune response | 0.0195423438037034 |
GO:0019210 | kinase inhibitor activity | 0.0195423438037034 |
GO:0002819 | regulation of adaptive immune response | 0.0195423438037034 |
GO:0002822 | regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. | 0.0195423438037034 |
GO:0010468 | regulation of gene expression | 0.0195423438037034 |
GO:0031323 | regulation of cellular metabolic process | 0.0208470082702882 |
GO:0050871 | positive regulation of B cell activation | 0.0208470082702882 |
GO:0016447 | somatic recombination of immunoglobulin gene segments | 0.0208470082702882 |
GO:0019222 | regulation of metabolic process | 0.0208470082702882 |
GO:0031347 | regulation of defense response | 0.0208470082702882 |
GO:0051241 | negative regulation of multicellular organismal process | 0.0208470082702882 |
GO:0050727 | regulation of inflammatory response | 0.0208470082702882 |
GO:0016444 | somatic cell DNA recombination | 0.0208470082702882 |
GO:0002562 | somatic diversification of immune receptors via germline recombination within a single locus | 0.0208470082702882 |
GO:0016070 | RNA metabolic process | 0.0208470082702882 |
GO:0006690 | icosanoid metabolic process | 0.0208470082702882 |
GO:0016445 | somatic diversification of immunoglobulins | 0.0208470082702882 |
GO:0002200 | somatic diversification of immune receptors | 0.0218430977084959 |
GO:0043170 | macromolecule metabolic process | 0.0222453518230858 |
GO:0050864 | regulation of B cell activation | 0.0243899157232587 |
GO:0002377 | immunoglobulin production | 0.0252756617130364 |
GO:0002440 | production of molecular mediator of immune response | 0.0253148365305417 |
GO:0048522 | positive regulation of cellular process | 0.0253148365305417 |
GO:0048583 | regulation of response to stimulus | 0.0271470582401027 |
GO:0019221 | cytokine and chemokine mediated signaling pathway | 0.0273279768087273 |
GO:0010467 | gene expression | 0.0295513593912224 |
GO:0003700 | transcription factor activity | 0.0295513593912224 |
GO:0048518 | positive regulation of biological process | 0.0309642625493989 |
GO:0044238 | primary metabolic process | 0.0336469501789967 |
GO:0044237 | cellular metabolic process | 0.0336585119279058 |
GO:0051251 | positive regulation of lymphocyte activation | 0.0338248111422986 |
GO:0019887 | protein kinase regulator activity | 0.0344361317682002 |
GO:0006139 | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 0.0356074807768266 |
GO:0019955 | cytokine binding | 0.0356074807768266 |
GO:0016064 | immunoglobulin mediated immune response | 0.0366900650795972 |
GO:0019724 | B cell mediated immunity | 0.0367149999362538 |
GO:0006310 | DNA recombination | 0.0372632124910298 |
GO:0019207 | kinase regulator activity | 0.0372632124910298 |
GO:0050794 | regulation of cellular process | 0.0404470684666517 |
GO:0051249 | regulation of lymphocyte activation | 0.0407069757311571 |
GO:0042113 | B cell activation | 0.0411267233716689 |
GO:0050865 | regulation of cell activation | 0.0411267233716689 |
GO:0002250 | adaptive immune response | 0.0415255534530609 |
GO:0002460 | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 0.0415255534530609 |
GO:0002449 | lymphocyte mediated immunity | 0.0424038110968864 |
GO:0002443 | leukocyte mediated immunity | 0.0450674053215862 |
GO:0050789 | regulation of biological process | 0.0493197986807879 |
GO:0050776 | regulation of immune response | 0.0493197986807879 |
GO:0002682 | regulation of immune system process | 0.0496297266270087 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
gastrointestinal system | 1.37e-08 | 47 |
intestine | 2.12e-08 | 31 |
endoderm-derived structure | 2.97e-08 | 118 |
endoderm | 2.97e-08 | 118 |
presumptive endoderm | 2.97e-08 | 118 |
digestive system | 7.50e-08 | 116 |
digestive tract | 7.50e-08 | 116 |
primitive gut | 7.50e-08 | 116 |
subdivision of digestive tract | 3.21e-07 | 114 |
mucosa | 4.89e-07 | 15 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 0.276983 |
MA0004.1 | 0.536396 |
MA0006.1 | 0.945134 |
MA0007.1 | 0.52077 |
MA0009.1 | 0.987341 |
MA0014.1 | 0.558098 |
MA0017.1 | 1.00628 |
MA0019.1 | 0.800946 |
MA0024.1 | 2.16928 |
MA0025.1 | 1.22395 |
MA0027.1 | 2.64231 |
MA0028.1 | 0.969171 |
MA0029.1 | 0.920529 |
MA0030.1 | 0.927235 |
MA0031.1 | 0.890871 |
MA0038.1 | 0.686534 |
MA0040.1 | 1.00009 |
MA0041.1 | 0.457338 |
MA0042.1 | 0.443591 |
MA0043.1 | 1.08567 |
MA0046.1 | 1.02391 |
MA0048.1 | 0.161427 |
MA0050.1 | 0.57678 |
MA0051.1 | 0.695779 |
MA0052.1 | 1.00829 |
MA0055.1 | 0.0585191 |
MA0056.1 | 0 |
MA0057.1 | 0.895081 |
MA0058.1 | 0.436487 |
MA0059.1 | 1.14076 |
MA0060.1 | 0.275911 |
MA0061.1 | 1.49922 |
MA0063.1 | 0 |
MA0066.1 | 0.675169 |
MA0067.1 | 1.33603 |
MA0068.1 | 0.153907 |
MA0069.1 | 1.00864 |
MA0070.1 | 0.998765 |
MA0071.1 | 0.575909 |
MA0072.1 | 0.990133 |
MA0073.1 | 0.753052 |
MA0074.1 | 0.638014 |
MA0076.1 | 1.04996 |
MA0077.1 | 0.968053 |
MA0078.1 | 0.729877 |
MA0081.1 | 0.473489 |
MA0083.1 | 1.08487 |
MA0084.1 | 1.66561 |
MA0087.1 | 1.04109 |
MA0088.1 | 0.358337 |
MA0089.1 | 0 |
MA0090.1 | 0.500693 |
MA0091.1 | 0.55008 |
MA0092.1 | 0.501022 |
MA0093.1 | 0.988233 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.626021 |
MA0101.1 | 0.458688 |
MA0103.1 | 0.398766 |
MA0105.1 | 2.43957 |
MA0106.1 | 0.737893 |
MA0107.1 | 0.392331 |
MA0108.2 | 0.824407 |
MA0109.1 | 0 |
MA0111.1 | 0.515457 |
MA0113.1 | 0.708789 |
MA0114.1 | 0.822296 |
MA0115.1 | 1.08851 |
MA0116.1 | 0.359483 |
MA0117.1 | 1.05576 |
MA0119.1 | 0.459301 |
MA0122.1 | 1.07591 |
MA0124.1 | 1.28237 |
MA0125.1 | 1.20757 |
MA0130.1 | 0 |
MA0131.1 | 0.796279 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 1.1226 |
MA0136.1 | 0.658622 |
MA0139.1 | 0.243463 |
MA0140.1 | 0.625902 |
MA0141.1 | 1.07584 |
MA0142.1 | 0.876028 |
MA0143.1 | 0.725672 |
MA0144.1 | 0.307873 |
MA0145.1 | 0.119202 |
MA0146.1 | 0.153598 |
MA0147.1 | 0.858298 |
MA0148.1 | 0.553294 |
MA0149.1 | 0.464445 |
MA0062.2 | 1.11803 |
MA0035.2 | 0.630778 |
MA0039.2 | 0.181031 |
MA0138.2 | 0.788113 |
MA0002.2 | 0.246463 |
MA0137.2 | 0.416331 |
MA0104.2 | 0.723439 |
MA0047.2 | 0.685741 |
MA0112.2 | 0.37938 |
MA0065.2 | 0.380324 |
MA0150.1 | 0.520653 |
MA0151.1 | 0 |
MA0152.1 | 0.685852 |
MA0153.1 | 1.13945 |
MA0154.1 | 0.159217 |
MA0155.1 | 0.132921 |
MA0156.1 | 1.04798 |
MA0157.1 | 0.843181 |
MA0158.1 | 0 |
MA0159.1 | 0.331229 |
MA0160.1 | 0.556423 |
MA0161.1 | 0 |
MA0162.1 | 0.70356 |
MA0163.1 | 1.03138 |
MA0164.1 | 0.658997 |
MA0080.2 | 0.393257 |
MA0018.2 | 0.669032 |
MA0099.2 | 0.781628 |
MA0079.2 | 0.730639 |
MA0102.2 | 1.7182 |
MA0258.1 | 0.290587 |
MA0259.1 | 1.5079 |
MA0442.1 | 0 |