UBERON:0000956: Difference between revisions
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|has_quality= | |has_quality= | ||
|id=UBERON:0000956 | |id=UBERON:0000956 | ||
|is_a=UBERON: | |is_a=UBERON:0010314 ;;UBERON:0016548 | ||
|is_obsolete= | |is_obsolete= | ||
|located_in= | |located_in= | ||
|name=cerebral cortex | |name=cerebral cortex | ||
|namespace= | |namespace=FANTOM | ||
|obo_creation_date= | |obo_creation_date= | ||
|part_of=UBERON:0000203;;UBERON: | |part_of=UBERON:0000203;;UBERON:0005401 | ||
|preceded_by= | |preceded_by= | ||
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.owl;;IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl | |property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.owl;;IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl | ||
Latest revision as of 17:12, 12 September 2014
| Name: | cerebral cortex | ||
|---|---|---|---|
| Namespace: | FANTOM | ||
| Definition: | "The cerebral cortex is a structure within the brain that plays a key role in memory, attention, perceptual awareness, thought, language, and consciousness. It constitutes the outermost layer of the cerebrum. In preserved brains, it has a grey color, hence the name 'grey matter'. Grey matter is formed by neurons and their unmyelinated fibers, whereas the white matter below the grey matter of the cortex is formed predominantly by myelinated axons interconnecting different regions of the central nervous system. The human cerebral cortex is 2遯ｶ�4 mm (0.08遯ｶ�0.16 inches) thick. The surface of the cerebral cortex is folded in large mammals, such that more than two-thirds of the cortical surface is buried in the grooves, called 'sulci. ' The phylogenetically most recent part of the cerebral cortex, the neocortex, also called isocortex, is differentiated into six horizontal layers; the more ancient part of the cerebral cortex, the hippocampus (also called archicortex), has at most three cellular layers, and is divided into subfields. Relative variations in thickness or cell type (among other parameters) allow us to distinguish between different neocortical architectonic fields. The geometry of at least some of these fields seems to be related to the anatomy of the cortical folds, and, for example, layers in the upper part of the cortical ridges seem to be more clearly differentiated than in its deeper parts. [WP,unvetted]." [Wikipedia:Cerebral_cortex] | ||
| Xrefs: |
| ||
| Synonyms: |
"brain cortex" RELATED [BTO:0000233] "cortex cerebri" RELATED LATIN [Wikipedia:Cerebral_cortex] "cortex of cerebral hemisphere" EXACT [] "pallium of the brain" RELATED [BTO:0000233] | ||
| Comments: | This class was created automatically from a combination of ontologies | ||
| Alt_id: | UBERON:FBbt_00003625-FMA_61830-MA_0000185-MIAA_0000108 | ||
| Subset: | uberon_slim |
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | UBERON:0010314(structure with developmental contribution from neural crest),UBERON:0016548(central nervous system gray matter layer) |
|---|---|
| part_of: | UBERON:0000203(pallium),UBERON:0005401(cerebral hemisphere grey matter) |
Children
| derives from: | FF:0011469 (mouse cortex- neonate N30 sample),FF:0011525 (cortex- adult sample) |
|---|---|
| part of: | UBERON:0001950 (neocortex),UBERON:0002022 (insula),CL:0002605 (astrocyte of the cerebral cortex),CL:0002609 (neuron of cerebral cortex),UBERON:0002619 (regional part of cerebral cortex),CL:0010012 (cerebral cortex neuron),CL:1001579 (cerebral cortex glial cell) |
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Human (Homo sapiens)
- 10031-101E4 (temporal lobe, adult, pool1)
- 10032-101E5 (postcentral gyrus, adult, pool1)
- 10034-101E7 (parietal lobe, adult, pool1)
- 10036-101E9 (occipital pole, adult, pool1)
- 10039-101F3 (insula, adult, pool1)
- 10040-101F4 (frontal lobe, adult, pool1)
- 10071-101I8 (duodenum, fetal, donor1)
- 10072-101I9 (parietal lobe, fetal, donor1)
- 10073-102A1 (occipital lobe, fetal, donor1)
- 10076-102A4 (occipital lobe, adult, donor1)
... further results Mouse (Mus musculus)
- 10031-101E4 (temporal lobe, adult, pool1)
- 10032-101E5 (postcentral gyrus, adult, pool1)
- 10034-101E7 (parietal lobe, adult, pool1)
- 10036-101E9 (occipital pole, adult, pool1)
- 10039-101F3 (insula, adult, pool1)
- 10040-101F4 (frontal lobe, adult, pool1)
- 10071-101I8 (duodenum, fetal, donor1)
- 10072-101I9 (parietal lobe, fetal, donor1)
- 10073-102A1 (occipital lobe, fetal, donor1)
- 10076-102A4 (occipital lobe, adult, donor1)
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0000956 (cerebral cortex), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
| P-value | FFCP | Short description |
|---|---|---|
| 1.52e-129 | FFCP PHASE1:Hg19::chr10:11047712..11047726,+#_007fcf0a6f065fa9b27f875396f4e0ad | p@chr10:11047712..11047726, + |
| 1.52e-129 | FFCP PHASE2:Hg19::chr10:11047712..11047726,+#_007fcf0a6f065fa9b27f875396f4e0ad | p@chr10:11047712..11047726, + |
| 1.72e-126 | FFCP PHASE1:Hg19::chr8:89554929..89554960,+#_35e49b96af43010478ba93712f9d70fb | p1@ENST00000518631 |
| 1.72e-126 | FFCP PHASE2:Hg19::chr8:89554929..89554960,+#_35e49b96af43010478ba93712f9d70fb | p1@ENST00000518631 |
| 2.83e-119 | FFCP PHASE2:Hg19::chr10:10504250..10504278,+#_83820b7e69310930181ae90b8ee2c2c9 | p@chr10:10504250..10504278, + |
| 2.83e-119 | FFCP PHASE1:Hg19::chr10:10504250..10504278,+#_83820b7e69310930181ae90b8ee2c2c9 | p@chr10:10504250..10504278, + |
| 4.39e-119 | FFCP PHASE2:Hg19::chr18:70305745..70305761,-#_118853884aa0986c45424448fbd77d53 | p@chr18:70305745..70305761, - |
| 4.39e-119 | FFCP PHASE1:Hg19::chr18:70305745..70305761,-#_118853884aa0986c45424448fbd77d53 | p@chr18:70305745..70305761, - |
| 1.91e-117 | FFCP PHASE1:Hg19::chr18:70305621..70305634,-#_5f2b967fb1a996bbc440bf470f22d7fe | p@chr18:70305621..70305634, - |
| 1.91e-117 | FFCP PHASE2:Hg19::chr18:70305621..70305634,-#_5f2b967fb1a996bbc440bf470f22d7fe | p@chr18:70305621..70305634, - |
| 2.42e-117 | FFCP PHASE2:Hg19::chr22:43821065..43821115,+#_0ba31101bbea2454bbe13fbf682efad5 | p4@MPPED1 |
| 2.42e-117 | FFCP PHASE1:Hg19::chr22:43821065..43821115,+#_0ba31101bbea2454bbe13fbf682efad5 | p4@MPPED1 |
| 2.3e-113 | FFCP PHASE1:Hg19::chr10:11047746..11047768,+#_f3aee9bb15e66839fb8e3e56e0a5237b | p@chr10:11047746..11047768, + |
| 2.3e-113 | FFCP PHASE2:Hg19::chr10:11047746..11047768,+#_f3aee9bb15e66839fb8e3e56e0a5237b | p@chr10:11047746..11047768, + |
| 4.95e-111 | FFCP PHASE2:Hg19::chr19:54462560..54462571,+#_c37dc8ef1cb8370821ba6113f45fbfe8 | p@chr19:54462560..54462571, + |
| 4.95e-111 | FFCP PHASE1:Hg19::chr19:54462560..54462571,+#_c37dc8ef1cb8370821ba6113f45fbfe8 | p@chr19:54462560..54462571, + |
| 2.54e-110 | FFCP PHASE1:Hg19::chr10:11046599..11046616,+#_a2a6b84d54d3ef10d455bf3716a76cf9 | p@chr10:11046599..11046616, + |
| 2.54e-110 | FFCP PHASE2:Hg19::chr10:11046599..11046616,+#_a2a6b84d54d3ef10d455bf3716a76cf9 | p@chr10:11046599..11046616, + |
| 6.85e-110 | FFCP PHASE2:Hg19::chr8:110987986..110988010,-#_7fb3613dcf128e8214870374b6d7308b | p1@KCNV1 |
| 6.85e-110 | FFCP PHASE1:Hg19::chr8:110987986..110988010,-#_7fb3613dcf128e8214870374b6d7308b | p1@KCNV1 |
| 8.08e-110 | FFCP PHASE1:Hg19::chr5:17404114..17404134,+#_40da6a5d6f5e47c1297680190de499c5 | p1@ENST00000508677 |
| 8.08e-110 | FFCP PHASE2:Hg19::chr5:17404114..17404134,+#_40da6a5d6f5e47c1297680190de499c5 | p1@ENST00000508677 |
| 1.16e-109 | FFCP PHASE2:Hg19::chr11:133402367..133402378,-#_d16a512010c29fd97d12cb61785cf845 | p8@OPCML |
| 1.16e-109 | FFCP PHASE1:Hg19::chr11:133402367..133402378,-#_d16a512010c29fd97d12cb61785cf845 | p8@OPCML |
| 6.25e-109 | FFCP PHASE1:Hg19::chr14:70546905..70546935,-#_09227a5dd2b9a268130071e186cd7e18 | p3@SLC8A3 |
| 6.25e-109 | FFCP PHASE2:Hg19::chr14:70546905..70546935,-#_09227a5dd2b9a268130071e186cd7e18 | p3@SLC8A3 |
| 4.02e-108 | FFCP PHASE1:Hg19::chr16:758668..758696,+#_33471c08c3aa347b8439e6f6379590f6 | p@chr16:758668..758696, + |
| 4.02e-108 | FFCP PHASE2:Hg19::chr16:758668..758696,+#_33471c08c3aa347b8439e6f6379590f6 | p@chr16:758668..758696, + |
| 5.1e-108 | FFCP PHASE2:Hg19::chr5:22754690..22754720,+#_ac59030947b7630d335f004b769bf8f0 | p@chr5:22754690..22754720, + |
| 5.1e-108 | FFCP PHASE1:Hg19::chr5:22754690..22754720,+#_ac59030947b7630d335f004b769bf8f0 | p@chr5:22754690..22754720, + |
| 5.75e-108 | FFCP PHASE2:Hg19::chr8:67405573..67405590,+#_264b1a491f6e62376942fcbab05d7d5e | p7@C8orf46 |
| 5.75e-108 | FFCP PHASE1:Hg19::chr8:67405573..67405590,+#_264b1a491f6e62376942fcbab05d7d5e | p7@C8orf46 |
| 1.84e-107 | FFCP PHASE2:Hg19::chr9:10612907..10612918,-#_f819d47ef50394e159e58b825ebecc7d | p17@PTPRD |
| 1.84e-107 | FFCP PHASE1:Hg19::chr9:10612907..10612918,-#_f819d47ef50394e159e58b825ebecc7d | p17@PTPRD |
| 6.72e-107 | FFCP PHASE1:Hg19::chr12:62585176..62585196,-#_8446e86da891eab73eb25d9554f44245 | p14@FAM19A2 |
| 6.72e-107 | FFCP PHASE2:Hg19::chr12:62585176..62585196,-#_8446e86da891eab73eb25d9554f44245 | p14@FAM19A2 |
| 8.42e-107 | FFCP PHASE2:Hg19::chr18:70305699..70305738,-#_aaf7c37f0bb9b20db03994c3f14b669b | p@chr18:70305699..70305738, - |
| 8.42e-107 | FFCP PHASE1:Hg19::chr18:70305699..70305738,-#_aaf7c37f0bb9b20db03994c3f14b669b | p@chr18:70305699..70305738, - |
| 1.04e-106 | FFCP PHASE1:Hg19::chr10:11047633..11047685,+#_65b69173a7af7cac8555926a17219161 | p@chr10:11047633..11047685, + |
| 1.04e-106 | FFCP PHASE2:Hg19::chr10:11047633..11047685,+#_65b69173a7af7cac8555926a17219161 | p@chr10:11047633..11047685, + |
| 1.12e-106 | FFCP PHASE1:Hg19::chr6:160311995..160312034,+#_bf8ddd181529c4f55590d5e6ea9e809d | p@chr6:160311995..160312034, + |
| 1.12e-106 | FFCP PHASE2:Hg19::chr6:160311995..160312034,+#_bf8ddd181529c4f55590d5e6ea9e809d | p@chr6:160311995..160312034, + |
| 2.02e-106 | FFCP PHASE2:Hg19::chr11:133402347..133402360,-#_0bce8224783e4e610808f3a08ff709d6 | p6@OPCML |
| 2.02e-106 | FFCP PHASE1:Hg19::chr11:133402347..133402360,-#_0bce8224783e4e610808f3a08ff709d6 | p6@OPCML |
| 2.02e-106 | FFCP PHASE2:Hg19::chr12:87232669..87232696,-#_0bce8224783e4e610808f3a08ff709d6 | p6@MGAT4C |
| 2.02e-106 | FFCP PHASE1:Hg19::chr12:87232669..87232696,-#_0bce8224783e4e610808f3a08ff709d6 | p6@MGAT4C |
| 6.73e-106 | FFCP PHASE1:Hg19::chr8:110986427..110986445,-#_745105a2c5f0ecf258911bc4cde03b7f | p4@KCNV1 |
| 6.73e-106 | FFCP PHASE2:Hg19::chr8:110986427..110986445,-#_745105a2c5f0ecf258911bc4cde03b7f | p4@KCNV1 |
| 1.11e-105 | FFCP PHASE1:Hg19::chr20:1975321..1975338,-#_8670327f7c7ffbc54297a78df948402e | p3@PDYN |
| 1.11e-105 | FFCP PHASE2:Hg19::chr20:1975321..1975338,-#_8670327f7c7ffbc54297a78df948402e | p3@PDYN |
| 1.34e-105 | FFCP PHASE1:Hg19::chr6:62390886..62390903,-#_c0303b7f36dcb6640b5e414d35e748b0 | p1@ENST00000511849 |
| 1.34e-105 | FFCP PHASE2:Hg19::chr6:62390886..62390903,-#_c0303b7f36dcb6640b5e414d35e748b0 | p1@ENST00000511849 |
| 1.34e-105 | FFCP PHASE1:Hg19::chr4:39064313..39064326,+#_c0303b7f36dcb6640b5e414d35e748b0 | p7@KLHL5 |
| 1.34e-105 | FFCP PHASE2:Hg19::chr4:39064313..39064326,+#_c0303b7f36dcb6640b5e414d35e748b0 | p7@KLHL5 |
| 2.69e-105 | FFCP PHASE2:Hg19::chr6:12718426..12718446,+#_b89283c07850b68ee87058a7e26f8404 | p24@PHACTR1 |
| 2.69e-105 | FFCP PHASE1:Hg19::chr6:12718426..12718446,+#_b89283c07850b68ee87058a7e26f8404 | p24@PHACTR1 |
| 4.19e-104 | FFCP PHASE2:Hg19::chr15:30231269..30231299,-#_123e121ca50f2e74e5638f326d832174 | p@chr15:30231269..30231299, - |
| 4.19e-104 | FFCP PHASE1:Hg19::chr15:30231269..30231299,-#_123e121ca50f2e74e5638f326d832174 | p@chr15:30231269..30231299, - |
| 5.28e-104 | FFCP PHASE2:Hg19::chr11:45564023..45564028,-#_dae9d0ab93afa38eebee4684fe1b8c0f | p1@ENST00000525855, p1@ENST00000527642, p1@ENST00000533315 |
| 5.28e-104 | FFCP PHASE1:Hg19::chr11:45564023..45564028,-#_dae9d0ab93afa38eebee4684fe1b8c0f | p1@ENST00000525855, p1@ENST00000527642, p1@ENST00000533315 |
| 1.57e-103 | FFCP PHASE2:Hg19::chr10:116852602..116852626,+#_b3291f9332015d616969b74ab76cdc1a | p5@ATRNL1 |
| 1.57e-103 | FFCP PHASE1:Hg19::chr10:116852602..116852626,+#_b3291f9332015d616969b74ab76cdc1a | p5@ATRNL1 |
| 2.22e-103 | FFCP PHASE1:Hg19::chr5:94621232..94621256,-#_f03201c3fbe0ee0b9968a78baaca9d89 | p@chr5:94621232..94621256, - |
| 2.22e-103 | FFCP PHASE2:Hg19::chr5:94621232..94621256,-#_f03201c3fbe0ee0b9968a78baaca9d89 | p@chr5:94621232..94621256, - |
| 2.73e-103 | FFCP PHASE1:Hg19::chr3:62359214..62359232,-#_573c910d140a255d12b8cb2ef693ce05 | p1@FEZF2 |
| 2.73e-103 | FFCP PHASE2:Hg19::chr3:62359214..62359232,-#_573c910d140a255d12b8cb2ef693ce05 | p1@FEZF2 |
| 3.26e-103 | FFCP PHASE1:Hg19::chr2:136343886..136343897,+#_a9f43fba58f1ddc771671634ceaa3dbb | p4@R3HDM1 |
| 3.26e-103 | FFCP PHASE2:Hg19::chr2:136343886..136343897,+#_a9f43fba58f1ddc771671634ceaa3dbb | p4@R3HDM1 |
| 1.5e-102 | FFCP PHASE1:Hg19::chr2:10508688..10508712,+#_64d8f2826862bcd6fd900f13321ea567 | p8@HPCAL1 |
| 1.5e-102 | FFCP PHASE2:Hg19::chr2:10508688..10508712,+#_64d8f2826862bcd6fd900f13321ea567 | p8@HPCAL1 |
| 2.05e-102 | FFCP PHASE2:Hg19::chr12:122794425..122794445,-#_187a23ed2a738e78779b27c93a6459d6 | p@chr12:122794425..122794445, - |
| 2.05e-102 | FFCP PHASE1:Hg19::chr12:122794425..122794445,-#_187a23ed2a738e78779b27c93a6459d6 | p@chr12:122794425..122794445, - |
| 3.64e-102 | FFCP PHASE1:Hg19::chr17:37764312..37764326,-#_a0d1d92de319ac0e41b97dca47f78996 | p2@NEUROD2 |
| 3.64e-102 | FFCP PHASE2:Hg19::chr17:37764312..37764326,-#_a0d1d92de319ac0e41b97dca47f78996 | p2@NEUROD2 |
| 4.48e-102 | FFCP PHASE1:Hg19::chr12:14133429..14133438,-#_a4a0bd248ab2a63d10610a38ed0198d6 | p3@GRIN2B |
| 4.48e-102 | FFCP PHASE2:Hg19::chr12:14133429..14133438,-#_a4a0bd248ab2a63d10610a38ed0198d6 | p3@GRIN2B |
| 1.95e-101 | FFCP PHASE2:Hg19::chr16:758701..758727,+#_e47e7dc7876671124dd9feeff69fd47f | p@chr16:758701..758727, + |
| 1.95e-101 | FFCP PHASE1:Hg19::chr16:758701..758727,+#_e47e7dc7876671124dd9feeff69fd47f | p@chr16:758701..758727, + |
| 5.99e-101 | FFCP PHASE1:Hg19::chr1:177134348..177134360,-#_09aafd927007e0f32674923a45cc260e | p10@ASTN1 |
| 5.99e-101 | FFCP PHASE2:Hg19::chr1:177134348..177134360,-#_09aafd927007e0f32674923a45cc260e | p10@ASTN1 |
| 6.35e-101 | FFCP PHASE2:Hg19::chr5:80255907..80255942,+#_7e51d68eae0281203465e5410025bf75 | p@chr5:80255907..80255942, + |
| 6.35e-101 | FFCP PHASE1:Hg19::chr5:80255907..80255942,+#_7e51d68eae0281203465e5410025bf75 | p@chr5:80255907..80255942, + |
| 8.54e-101 | FFCP PHASE1:Hg19::chr11:84431459..84431498,-#_0c346de9256863a02a356f0aeffe19ff | p@chr11:84431459..84431498, - |
| 8.54e-101 | FFCP PHASE2:Hg19::chr11:84431459..84431498,-#_0c346de9256863a02a356f0aeffe19ff | p@chr11:84431459..84431498, - |
| 1.54e-100 | FFCP PHASE1:Hg19::chr17:36757284..36757327,+#_30fed1a1bb921e1c097cc76888449390 | p@chr17:36757284..36757327, + |
| 1.54e-100 | FFCP PHASE2:Hg19::chr17:36757284..36757327,+#_30fed1a1bb921e1c097cc76888449390 | p@chr17:36757284..36757327, + |
| 1.94e-100 | FFCP PHASE1:Hg19::chr4:6474536..6474563,-#_7a1c6a84d34764f659214c211b43228d | p9@PPP2R2C |
| 1.94e-100 | FFCP PHASE2:Hg19::chr4:6474536..6474563,-#_7a1c6a84d34764f659214c211b43228d | p9@PPP2R2C |
| 5.35e-100 | FFCP PHASE2:Hg19::chr1:50575292..50575326,+#_ad64726cafa7830aed518f1bd3a02872 | p8@ELAVL4 |
| 5.35e-100 | FFCP PHASE1:Hg19::chr1:50575292..50575326,+#_ad64726cafa7830aed518f1bd3a02872 | p8@ELAVL4 |
| 5.71e-100 | FFCP PHASE1:Hg19::chr10:14372834..14372846,-#_f61db5ee99a971e621c07c1c41c50662 | p12@FRMD4A |
| 5.71e-100 | FFCP PHASE2:Hg19::chr10:14372834..14372846,-#_f61db5ee99a971e621c07c1c41c50662 | p12@FRMD4A |
| 7.95e-100 | FFCP PHASE2:Hg19::chr5:56910048..56910074,+#_5c7ef5b83c337e6e3dcffb1422687d5f | p1@ENST00000509844 |
| 7.95e-100 | FFCP PHASE1:Hg19::chr5:56910048..56910074,+#_5c7ef5b83c337e6e3dcffb1422687d5f | p1@ENST00000509844 |
| 9.35e-100 | FFCP PHASE2:Hg19::chr6:53976259..53976270,+#_59bb9274500a85ae43eb25399e402f57 | p5@MLIP |
| 9.35e-100 | FFCP PHASE1:Hg19::chr6:53976259..53976270,+#_59bb9274500a85ae43eb25399e402f57 | p5@MLIP |
| 1.13e-99 | FFCP PHASE2:Hg19::chr6:98264571..98264591,+#_7b2a3aad6fb9c0956025c3f7e431c3d8 | p@chr6:98264571..98264591, + |
| 1.13e-99 | FFCP PHASE1:Hg19::chr6:98264571..98264591,+#_7b2a3aad6fb9c0956025c3f7e431c3d8 | p@chr6:98264571..98264591, + |
| 2.26e-99 | FFCP PHASE2:Hg19::chr5:63256975..63257005,-#_83830d5fad20583908823eba4dd5a0ec | p1@HTR1A |
| 2.26e-99 | FFCP PHASE1:Hg19::chr5:63256975..63257005,-#_83830d5fad20583908823eba4dd5a0ec | p1@HTR1A |
