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{{UBERON
{{UBERON
|id=UBERON:0000042
|alt_id=
|name=serous membrane
|namespace=
|def="a smooth membrane consisting of a thin layer of cells which excrete serous fluid. Serous membranes line and enclose several body cavities, known as serous cavities, where they secrete a lubricating fluid which reduces friction from muscle movement. Serosa is not to be confused with adventitia, a connective tissue layer which binds together structures rather than reducing friction between them. Each serous membrane is composed of a secretory epithelial layer and a connective tissue layer underneath. The epithelial layer, known as mesothelium, consists of a single layer of avascular flat nucleated cells (cuboidal epithelium) which produce the lubricating serous fluid. This fluid has a consistency similar to thin mucus. These cells are bound tightly to the underlying connective tissue. The connective tissue layer provides the blood vessels and nerves for the overlying secretory cells, and also serves as the binding layer which allows the whole serous membrane to adhere to organs and other structures.[WP]." [Wikipedia:Serosa, Wikipedia:Serous_membrane]
|xref=FMA:45637;;FMA:9581;;GAID:19;;http://upload.wikimedia.org/wikipedia/commons/4/4e/Ens.png;;http://upload.wikimedia.org/wikipedia/en/thumb/4/4e/Ens.png/200px-Ens.png;;MESH:A.10.615.789;;ncithesaurus:Serosa;;SCTID:362878009;;TAO:0005425;;ZFA:0005425
|is_a=UBERON:0004120;;UBERON:0004457
|synonym="serosa" EXACT [];;"tunica serosa" EXACT [FMA:9581];;"tunica seroso" RELATED LATIN [Wikipedia:Serous_membrane];;"wall of serous sac" EXACT [FMA:9581]
|comment=TODO - add generic membrane parent? TODO - split into serosa and serous membrane?
|comment=TODO - add generic membrane parent? TODO - split into serosa and serous membrane?
|alt_id=
|disjoint_from=
|union_of=
|created_by=
|created_by=
|obo_creation_date=
|def="a smooth membrane consisting of a thin layer of cells which excrete serous fluid. Serous membranes line and enclose several body cavities, known as serous cavities, where they secrete a lubricating fluid which reduces friction from muscle movement. Serosa is not to be confused with adventitia, a connective tissue layer which binds together structures rather than reducing friction between them. Each serous membrane is composed of a secretory epithelial layer and a connective tissue layer underneath. The epithelial layer, known as mesothelium, consists of a single layer of avascular flat nucleated cells (cuboidal epithelium) which produce the lubricating serous fluid. This fluid has a consistency similar to thin mucus. These cells are bound tightly to the underlying connective tissue. The connective tissue layer provides the blood vessels and nerves for the overlying secretory cells, and also serves as the binding layer which allows the whole serous membrane to adhere to organs and other structures.[WP]." [Wikipedia:Serosa, Wikipedia:Serous_membrane]
|subset=uberon_slim;;vertebrate_core
|derives_from=
|derives_from=
|develops_from=UBERON:0000926
|develops_from=UBERON:0000926
|disjoint_from=
|has_quality=
|has_quality=
|id=UBERON:0000042
|is_a=UBERON:0004120 ;;UBERON:0004457
|is_obsolete=
|located_in=
|located_in=
|part_of=
|name=serous membrane
|namespace=
|obo_creation_date=
|part_of=UBERON:0000060
|preceded_by=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl;;UBPROP:0000001 "A multi-tissue structure that is comprised of a secretory epithelial layer and a connective tissue layer.[TAO]" xsd:string
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl;;UBPROP:0000001 "A multi-tissue structure that is comprised of a secretory epithelial layer and a connective tissue layer.[TAO]" xsd:string
|is_obsolete=
|subset=uberon_slim;;vertebrate_core
|preceded_by=
|synonym="serosa" EXACT [];;"tunica serosa" EXACT [FMA:9581];;"tunica seroso" RELATED LATIN [Wikipedia:Serous_membrane];;"wall of serous sac" EXACT [FMA:9581]
|union_of=
|xref=FMA:45637;;FMA:9581;;GAID:19;;http://upload.wikimedia.org/wikipedia/commons/4/4e/Ens.png;;http://upload.wikimedia.org/wikipedia/en/thumb/4/4e/Ens.png/200px-Ens.png;;MESH:A.10.615.789;;ncithesaurus:Serosa;;SCTID:362878009;;TAO:0005425;;ZFA:0005425
}}
}}

Revision as of 10:49, 12 September 2014

Name:serous membrane
Definition:"a smooth membrane consisting of a thin layer of cells which excrete serous fluid. Serous membranes line and enclose several body cavities, known as serous cavities, where they secrete a lubricating fluid which reduces friction from muscle movement. Serosa is not to be confused with adventitia, a connective tissue layer which binds together structures rather than reducing friction between them. Each serous membrane is composed of a secretory epithelial layer and a connective tissue layer underneath. The epithelial layer, known as mesothelium, consists of a single layer of avascular flat nucleated cells (cuboidal epithelium) which produce the lubricating serous fluid. This fluid has a consistency similar to thin mucus. These cells are bound tightly to the underlying connective tissue. The connective tissue layer provides the blood vessels and nerves for the overlying secretory cells, and also serves as the binding layer which allows the whole serous membrane to adhere to organs and other structures.[WP]." [Wikipedia:Serosa, Wikipedia:Serous_membrane]
Xrefs:
links:

FMA:45637
FMA:9581
GAID:19
[ Ens.png Ens.png]
[ 200px-Ens.png 200px-Ens.png]
MESH:A.10.615.789
ncithesaurus:Serosa
SCTID:362878009
TAO:0005425

ZFA:0005425
Synonyms: "serosa" EXACT []
"tunica serosa" EXACT [FMA:9581]
"tunica seroso" RELATED LATIN [Wikipedia:Serous_membrane]
"wall of serous sac" EXACT [FMA:9581]
Comments:TODO - add generic membrane parent? TODO - split into serosa and serous membrane?
Subset: uberon_slim
vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0004120(mesoderm-derived structure),UBERON:0004457(cavity lining)
develops_from:UBERON:0000926(mesoderm)
part_of:UBERON:0000060(anatomical wall)



Children

is a:UBERON:0002095 (mesentery),UBERON:0002358 (peritoneum),UBERON:0004782 (gastrointestinal system serosa),UBERON:0007616 (layer of synovial tissue)
part of:UBERON:0001136 (mesothelium)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

Human (Homo sapiens)

... further results


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0000042 (serous membrane), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
1.36e-86FFCP PHASE2:Mm9::chr19:45161527..45161539,+#_303f27f7cfa44691c3838396829dc151p@chr19:45161527..45161539, +
1.36e-86FFCP PHASE1:Mm9::chr19:45161527..45161539,+#_303f27f7cfa44691c3838396829dc151p@chr19:45161527..45161539, +
4.43e-82FFCP PHASE1:Hg19::chr18:20122740..20122747,+#_121731cc5e62db355e2842fb42f972fbp@chr18:20122740..20122747, +
4.43e-82FFCP PHASE2:Hg19::chr18:20122740..20122747,+#_121731cc5e62db355e2842fb42f972fbp@chr18:20122740..20122747, +
1.01e-74FFCP PHASE2:Mm9::chr19:45224323..45224368,+#_e744702754e0f03a1ce7d82b9b07a9a2p@chr19:45224323..45224368, +
1.01e-74FFCP PHASE1:Mm9::chr19:45224323..45224368,+#_e744702754e0f03a1ce7d82b9b07a9a2p@chr19:45224323..45224368, +
2.48e-72FFCP PHASE1:Mm9::chr13:108293519..108293533,-#_ce49d330969032f5f6ca71e8c3685405p@chr13:108293519..108293533, -
2.48e-72FFCP PHASE2:Mm9::chr13:108293519..108293533,-#_ce49d330969032f5f6ca71e8c3685405p@chr13:108293519..108293533, -
1.35e-65FFCP PHASE1:Mm9::chr19:42116119..42116133,+#_4e66c9581eb1236208ee7751ba251af5p@chr19:42116119..42116133, +
1.35e-65FFCP PHASE2:Mm9::chr19:42116119..42116133,+#_4e66c9581eb1236208ee7751ba251af5p@chr19:42116119..42116133, +
4.13e-51FFCP PHASE2:Hg19::chr15:39087815..39087824,-#_0c43ca5b227c13312fa7bbdaf52f2c45p@chr15:39087815..39087824, -
4.13e-51FFCP PHASE1:Hg19::chr15:39087815..39087824,-#_0c43ca5b227c13312fa7bbdaf52f2c45p@chr15:39087815..39087824, -
5.59e-50FFCP PHASE2:Hg19::chr7:73484112..73484119,+#_7530e55ac7881c3e13a34e0c0a739216p43@ELN
5.59e-50FFCP PHASE1:Hg19::chr7:73484112..73484119,+#_7530e55ac7881c3e13a34e0c0a739216p43@ELN
1.09e-46FFCP PHASE2:Mm9::chr19:45224993..45225027,-#_a313da0598156203fb783a1f070e4d3fp@chr19:45224993..45225027, -
1.09e-46FFCP PHASE1:Mm9::chr19:45224993..45225027,-#_a313da0598156203fb783a1f070e4d3fp@chr19:45224993..45225027, -
1.86e-46FFCP PHASE2:Mm9::chr2:124537273..124537278,-#_9c9e5c3a442c2e8f8e44b5f3c9ba8994p@chr2:124537273..124537278, -
1.86e-46FFCP PHASE1:Mm9::chr2:124537273..124537278,-#_9c9e5c3a442c2e8f8e44b5f3c9ba8994p@chr2:124537273..124537278, -
2.72e-42FFCP PHASE1:Hg19::chr19:18718172..18718197,+#_1df9f78f998b54979cdb83dbf6276149p@chr19:18718172..18718197, +
2.72e-42FFCP PHASE2:Hg19::chr19:18718172..18718197,+#_1df9f78f998b54979cdb83dbf6276149p@chr19:18718172..18718197, +
8.75e-42FFCP PHASE2:Hg19::chr19:18898355..18898369,+#_ca91e78746f2af5a7e0d449c5a9cadf0p@chr19:18898355..18898369, +
8.75e-42FFCP PHASE1:Hg19::chr19:18898355..18898369,+#_ca91e78746f2af5a7e0d449c5a9cadf0p@chr19:18898355..18898369, +
8.75e-42FFCP PHASE2:Hg19::chr19:18900805..18900820,-#_ca91e78746f2af5a7e0d449c5a9cadf0p@chr19:18900805..18900820, -
8.75e-42FFCP PHASE1:Hg19::chr19:18900805..18900820,-#_ca91e78746f2af5a7e0d449c5a9cadf0p@chr19:18900805..18900820, -
2.56e-41FFCP PHASE1:Hg19::chr19:18898324..18898353,+#_d13e4d0acf1c51b80d47678c25ed0b09p@chr19:18898324..18898353, +
2.56e-41FFCP PHASE2:Hg19::chr19:18898324..18898353,+#_d13e4d0acf1c51b80d47678c25ed0b09p@chr19:18898324..18898353, +
9.04e-41FFCP PHASE1:Hg19::chr7:37947092..37947121,+#_8e4310ad25b30fb8a84dbf62a78dfbeap2@CU691333
9.04e-41FFCP PHASE2:Hg19::chr7:37947092..37947121,+#_8e4310ad25b30fb8a84dbf62a78dfbeap2@CU691333
1.54e-40FFCP PHASE2:Hg19::chr7:37947182..37947207,-#_735b13fe61f3e6fa039411b519f47cebp@chr7:37947182..37947207, -
1.54e-40FFCP PHASE1:Hg19::chr7:37947182..37947207,-#_735b13fe61f3e6fa039411b519f47cebp@chr7:37947182..37947207, -
2.32e-40FFCP PHASE1:Hg19::chr12:8814772..8814786,-#_809e87696e6f29a09d5c5a81caa9460fp13@MFAP5
2.32e-40FFCP PHASE2:Hg19::chr12:8814772..8814786,-#_809e87696e6f29a09d5c5a81caa9460fp13@MFAP5
1.42e-39FFCP PHASE2:Hg19::chr19:18900031..18900054,+#_78c640f9af5ce221b03ad23880d73590p@chr19:18900031..18900054, +
1.42e-39FFCP PHASE1:Hg19::chr19:18900031..18900054,+#_78c640f9af5ce221b03ad23880d73590p@chr19:18900031..18900054, +
1.92e-39FFCP PHASE1:Mm9::chr10:24966689..24966692,-#_309da9850b933d3070740dff5bbd09b2p@chr10:24966689..24966692, -
1.92e-39FFCP PHASE2:Mm9::chr10:24966689..24966692,-#_309da9850b933d3070740dff5bbd09b2p@chr10:24966689..24966692, -
2.2e-39FFCP PHASE2:Hg19::chr19:18899114..18899135,-#_ee47bd37576183ccab7e65a681d33dedp@chr19:18899114..18899135, -
2.2e-39FFCP PHASE1:Hg19::chr19:18899114..18899135,-#_ee47bd37576183ccab7e65a681d33dedp@chr19:18899114..18899135, -
2.54e-39FFCP PHASE2:Hg19::chr19:18896512..18896527,-#_5c31f3cdf53dcd4baff50621dbc585bfp@chr19:18896512..18896527, -
2.54e-39FFCP PHASE1:Hg19::chr19:18896512..18896527,-#_5c31f3cdf53dcd4baff50621dbc585bfp@chr19:18896512..18896527, -
1.63e-38FFCP PHASE1:Hg19::chr15:81242954..81242966,+#_31d0d2a426aa11ea9432acc9c416cc5dp@chr15:81242954..81242966, +
1.63e-38FFCP PHASE2:Hg19::chr15:81242954..81242966,+#_31d0d2a426aa11ea9432acc9c416cc5dp@chr15:81242954..81242966, +
1.32e-37FFCP PHASE1:Hg19::chr19:18893611..18893635,-#_931da52399d885f9f85314b0ad7bc246p1@AK094919
1.32e-37FFCP PHASE2:Hg19::chr4:112437251..112437278,+#_931da52399d885f9f85314b0ad7bc246p@chr4:112437251..112437278, +
1.32e-37FFCP PHASE1:Hg19::chr15:81225699..81225710,+#_931da52399d885f9f85314b0ad7bc246p26@KIAA1199
1.32e-37FFCP PHASE2:Hg19::chr15:81225699..81225710,+#_931da52399d885f9f85314b0ad7bc246p26@KIAA1199
1.32e-37FFCP PHASE1:Hg19::chr4:112437251..112437278,+#_931da52399d885f9f85314b0ad7bc246p@chr4:112437251..112437278, +
1.32e-37FFCP PHASE2:Hg19::chr19:18893611..18893635,-#_931da52399d885f9f85314b0ad7bc246p1@AK094919
1.34e-37FFCP PHASE2:Hg19::chr19:18896642..18896656,-#_b2521a4670b8565702baccbf22a4f69ap@chr19:18896642..18896656, -
1.34e-37FFCP PHASE1:Hg19::chr19:18896642..18896656,-#_b2521a4670b8565702baccbf22a4f69ap@chr19:18896642..18896656, -
5.84e-37FFCP PHASE2:Hg19::chr19:18899991..18900007,-#_c6079f6504e681854c12ac5b4ec20fd8p@chr19:18899991..18900007, -
5.84e-37FFCP PHASE1:Hg19::chr19:18899991..18900007,-#_c6079f6504e681854c12ac5b4ec20fd8p@chr19:18899991..18900007, -
7.41e-37FFCP PHASE2:Hg19::chr19:18899076..18899101,-#_d236ee679dfe105eebd2684f5e3a300fp@chr19:18899076..18899101, -
7.41e-37FFCP PHASE1:Hg19::chr19:18899076..18899101,-#_d236ee679dfe105eebd2684f5e3a300fp@chr19:18899076..18899101, -
3.25e-36FFCP PHASE2:Hg19::chr19:18900836..18900848,-#_00848f5cff408e59262fc27281a84e35p@chr19:18900836..18900848, -
3.25e-36FFCP PHASE1:Hg19::chr19:18900836..18900848,-#_00848f5cff408e59262fc27281a84e35p@chr19:18900836..18900848, -
1.87e-35FFCP PHASE2:Hg19::chr19:18899504..18899530,-#_50e91a2bbf69b820cfe80d8cfd495510p@chr19:18899504..18899530, -
1.87e-35FFCP PHASE1:Hg19::chr19:18899504..18899530,-#_50e91a2bbf69b820cfe80d8cfd495510p@chr19:18899504..18899530, -
5.37e-35FFCP PHASE2:Hg19::chr3:13670704..13670708,+#_3a5c1fc8a1f87022d891d5fa140fd8e6p@chr3:13670704..13670708, +
5.37e-35FFCP PHASE1:Hg19::chr3:13670704..13670708,+#_3a5c1fc8a1f87022d891d5fa140fd8e6p@chr3:13670704..13670708, +
5.88e-35FFCP PHASE2:Hg19::chr19:18709357..18709369,-#_37e1c61035513a01116006db16219b1cp@chr19:18709357..18709369, -
5.88e-35FFCP PHASE1:Hg19::chr19:18709357..18709369,-#_37e1c61035513a01116006db16219b1cp@chr19:18709357..18709369, -
6.77e-35FFCP PHASE2:Hg19::chr7:37947202..37947228,+#_a46526c74b296ae79e120f05d758acd4p1@CU691333
6.77e-35FFCP PHASE1:Hg19::chr7:37947202..37947228,+#_a46526c74b296ae79e120f05d758acd4p1@CU691333
1.12e-34FFCP PHASE2:Hg19::chr10:105428550..105428555,-#_d5b4adfe223457d1a848cbc5ce89baefp25@SH3PXD2A
1.12e-34FFCP PHASE1:Hg19::chr10:105428550..105428555,-#_d5b4adfe223457d1a848cbc5ce89baefp25@SH3PXD2A
1.41e-34FFCP PHASE2:Hg19::chr19:18893717..18893745,+#_238405261a80cecfd16a1767da0f8c33p@chr19:18893717..18893745, +
1.41e-34FFCP PHASE1:Hg19::chr19:18893717..18893745,+#_238405261a80cecfd16a1767da0f8c33p@chr19:18893717..18893745, +
1.64e-34FFCP PHASE1:Hg19::chr19:18899247..18899272,-#_01ddac0c064648f747f50eed9c7d7b75p@chr19:18899247..18899272, -
1.64e-34FFCP PHASE2:Hg19::chr19:18899247..18899272,-#_01ddac0c064648f747f50eed9c7d7b75p@chr19:18899247..18899272, -
1.9e-34FFCP PHASE1:Hg19::chr15:81242191..81242201,+#_f252265d1183fdabc3a8a83ce53bd37ep19@KIAA1199
1.9e-34FFCP PHASE2:Hg19::chr15:81242191..81242201,+#_f252265d1183fdabc3a8a83ce53bd37ep19@KIAA1199
2.01e-34FFCP PHASE2:Hg19::chr19:18896862..18896874,-#_ba1a3509a7df5d6a167d90e445c9aa0ep@chr19:18896862..18896874, -
2.01e-34FFCP PHASE1:Hg19::chr19:18896862..18896874,-#_ba1a3509a7df5d6a167d90e445c9aa0ep@chr19:18896862..18896874, -
2.68e-34FFCP PHASE1:Hg19::chr15:26342114..26342124,+#_4b5c96cd8ce518891111202c564a01efp@chr15:26342114..26342124, +
2.68e-34FFCP PHASE2:Hg19::chr15:26342114..26342124,+#_4b5c96cd8ce518891111202c564a01efp@chr15:26342114..26342124, +
2.85e-34FFCP PHASE1:Hg19::chr19:18897375..18897390,-#_b0298f18fcc04af60b7f11804d599284p4@COMP
2.85e-34FFCP PHASE2:Hg19::chr19:18897375..18897390,-#_b0298f18fcc04af60b7f11804d599284p4@COMP
4.28e-34FFCP PHASE2:Mm9::chr14:47707200..47707205,+#_ffbd357a86e0e1d8ec675ac44ef96a01p@chr14:47707200..47707205, +
4.28e-34FFCP PHASE1:Mm9::chr14:47707200..47707205,+#_ffbd357a86e0e1d8ec675ac44ef96a01p@chr14:47707200..47707205, +
5.19e-34FFCP PHASE1:Mm9::chr4:59686875..59686885,+#_bc811a081a063e91f0a5bfda9f5b857cp@chr4:59686875..59686885, +
5.19e-34FFCP PHASE2:Mm9::chr4:59686875..59686885,+#_bc811a081a063e91f0a5bfda9f5b857cp@chr4:59686875..59686885, +
5.98e-34FFCP PHASE2:Hg19::chr7:22259740..22259751,-#_1005718978f668bc236ef98d97bf066ap19@RAPGEF5
5.98e-34FFCP PHASE1:Hg19::chr8:22436248..22436259,+#_1005718978f668bc236ef98d97bf066ap11@PDLIM2
5.98e-34FFCP PHASE1:Hg19::chr11:56859693..56859701,-#_1005718978f668bc236ef98d97bf066ap@chr11:56859693..56859701, -
5.98e-34FFCP PHASE1:Hg19::chr10:98014908..98014919,-#_1005718978f668bc236ef98d97bf066ap@chr10:98014908..98014919, -
5.98e-34FFCP PHASE1:Hg19::chr9:133973310..133973321,+#_1005718978f668bc236ef98d97bf066ap18@AIF1L
5.98e-34FFCP PHASE2:Hg19::chr9:127269462..127269484,-#_1005718978f668bc236ef98d97bf066ap2@NR5A1
5.98e-34FFCP PHASE1:Hg19::chr11:925449..925458,+#_1005718978f668bc236ef98d97bf066ap17@AP2A2
5.98e-34FFCP PHASE2:Hg19::chr1:159172187..159172197,-#_1005718978f668bc236ef98d97bf066ap1@uc001ftm.1
5.98e-34FFCP PHASE2:Hg19::chr11:925449..925458,+#_1005718978f668bc236ef98d97bf066ap17@AP2A2
5.98e-34FFCP PHASE1:Hg19::chr9:124516729..124516752,+#_1005718978f668bc236ef98d97bf066ap@chr9:124516729..124516752, +
5.98e-34FFCP PHASE2:Hg19::chr8:22424743..22424759,-#_1005718978f668bc236ef98d97bf066ap1@ENST00000517384
5.98e-34FFCP PHASE1:Hg19::chrX:69645652..69645664,+#_1005718978f668bc236ef98d97bf066ap7@GDPD2
5.98e-34FFCP PHASE2:Hg19::chr11:56859608..56859619,-#_1005718978f668bc236ef98d97bf066ap@chr11:56859608..56859619, -
5.98e-34FFCP PHASE1:Hg19::chr11:56859584..56859589,-#_1005718978f668bc236ef98d97bf066ap@chr11:56859584..56859589, -
5.98e-34FFCP PHASE1:Hg19::chr21:28820954..28820963,-#_1005718978f668bc236ef98d97bf066ap3@ENST00000420186, p3@uc002ymh.2
5.98e-34FFCP PHASE1:Hg19::chr6:119812455..119812476,-#_1005718978f668bc236ef98d97bf066ap1@uc003pyn.1
5.98e-34FFCP PHASE1:Hg19::chr1:157811772..157811796,-#_1005718978f668bc236ef98d97bf066ap7@CD5L
5.98e-34FFCP PHASE2:Hg19::chr4:76901930..76901942,+#_1005718978f668bc236ef98d97bf066ap1@ENST00000501239










Property "Property value" (as page type) with input value "UBPROP:0000001 "A multi-tissue structure that is comprised of a secretory epithelial layer and a connective tissue layer.[TAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.

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