MCL coexpression mm9:2492

Phase1 CAGE Peaks

	Short description
Mm9::chr9:35231167..35231174,+	p3@Cdon
Mm9::chr9:35232460..35232473,+	p@chr9:35232460..35232473 +
Mm9::chr9:35232504..35232525,+	p@chr9:35232504..35232525 +
Mm9::chr9:35232543..35232569,+	p@chr9:35232543..35232569 +

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0045663	positive regulation of myoblast differentiation	0.00372541500027393
GO:0010172	embryonic body morphogenesis	0.00372541500027393
GO:0010171	body morphogenesis	0.00372541500027393
GO:0014902	myotube differentiation	0.00372541500027393
GO:0000768	syncytium formation by plasma membrane fusion	0.00372541500027393
GO:0007520	myoblast fusion	0.00372541500027393
GO:0045661	regulation of myoblast differentiation	0.00372541500027393
GO:0006949	syncytium formation	0.00372541500027393
GO:0016202	regulation of striated muscle development	0.0052155810003835
GO:0045026	plasma membrane fusion	0.0052155810003835
GO:0048628	myoblast maturation	0.00612032464330717
GO:0006944	membrane fusion	0.00612032464330717
GO:0048627	myoblast development	0.00612032464330717
GO:0001708	cell fate specification	0.00612032464330717
GO:0007224	smoothened signaling pathway	0.00695410800051134
GO:0045445	myoblast differentiation	0.00838218375061634
GO:0045597	positive regulation of cell differentiation	0.0100805347066236
GO:0042692	muscle cell differentiation	0.0119213280008766
GO:0048741	skeletal muscle fiber development	0.0119213280008766
GO:0048747	muscle fiber development	0.0119213280008766
GO:0051094	positive regulation of developmental process	0.0122406492866143
GO:0048469	cell maturation	0.0125309413645578
GO:0021700	developmental maturation	0.0147396854358664
GO:0007519	skeletal muscle development	0.0147464343760843
GO:0045165	cell fate commitment	0.0149016600010957
GO:0014706	striated muscle development	0.0174807934628238
GO:0045595	regulation of cell differentiation	0.0211106850015523
GO:0007517	muscle development	0.0220863889301954
GO:0009986	cell surface	0.0237655784500233
GO:0048598	embryonic morphogenesis	0.0249602805018353
GO:0016337	cell-cell adhesion	0.0249963329050638
GO:0016044	membrane organization and biogenesis	0.0271256779707445
GO:0050793	regulation of developmental process	0.0289001890930341
GO:0009790	embryonic development	0.0489782501506602

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
body cavity	4.69e-09	37
body cavity or lining	4.69e-09	37
multi-cellular organism	1.26e-08	333
body cavity precursor	2.40e-08	38
anatomical cavity	1.09e-07	39

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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