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MCL coexpression mm9:2492: Difference between revisions

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{{MCL_coexpression_mm9
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regulation of myoblast differentiation;0.00372541500027393;57810!GO:0010172;embryonic body morphogenesis;0.00372541500027393;57810!GO:0010171;body morphogenesis;0.00372541500027393;57810!GO:0014902;myotube differentiation;0.00372541500027393;57810!GO:0000768;syncytium formation by plasma membrane fusion;0.00372541500027393;57810!GO:0007520;myoblast fusion;0.00372541500027393;57810!GO:0045661;regulation of myoblast differentiation;0.00372541500027393;57810!GO:0006949;syncytium formation;0.00372541500027393;57810!GO:0016202;regulation of striated muscle development;0.0052155810003835;57810!GO:0045026;plasma membrane fusion;0.0052155810003835;57810!GO:0048628;myoblast maturation;0.00612032464330717;57810!GO:0006944;membrane fusion;0.00612032464330717;57810!GO:0048627;myoblast development;0.00612032464330717;57810!GO:0001708;cell fate specification;0.00612032464330717;57810!GO:0007224;smoothened signaling pathway;0.00695410800051134;57810!GO:0045445;myoblast differentiation;0.00838218375061634;57810!GO:0045597;positive regulation of cell differentiation;0.0100805347066236;57810!GO:0042692;muscle cell differentiation;0.0119213280008766;57810!GO:0048741;skeletal muscle fiber development;0.0119213280008766;57810!GO:0048747;muscle fiber development;0.0119213280008766;57810!GO:0051094;positive regulation of developmental process;0.0122406492866143;57810!GO:0048469;cell maturation;0.0125309413645578;57810!GO:0021700;developmental maturation;0.0147396854358664;57810!GO:0007519;skeletal muscle development;0.0147464343760843;57810!GO:0045165;cell fate commitment;0.0149016600010957;57810!GO:0014706;striated muscle development;0.0174807934628238;57810!GO:0045595;regulation of cell differentiation;0.0211106850015523;57810!GO:0007517;muscle development;0.0220863889301954;57810!GO:0009986;cell surface;0.0237655784500233;57810!GO:0048598;embryonic morphogenesis;0.0249602805018353;57810!GO:0016337;cell-cell adhesion;0.0249963329050638;57810!GO:0016044;membrane organization and biogenesis;0.0271256779707445;57810!GO:0050793;regulation of developmental process;0.0289001890930341;57810!GO:0009790;embryonic 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|gostat_on_MCL_coexpression=GO:0045663;positive regulation of myoblast differentiation;0.00372541500027393;57810!GO:0010172;embryonic body morphogenesis;0.00372541500027393;57810!GO:0010171;body morphogenesis;0.00372541500027393;57810!GO:0014902;myotube differentiation;0.00372541500027393;57810!GO:0000768;syncytium formation by plasma membrane fusion;0.00372541500027393;57810!GO:0007520;myoblast fusion;0.00372541500027393;57810!GO:0045661;regulation of myoblast differentiation;0.00372541500027393;57810!GO:0006949;syncytium formation;0.00372541500027393;57810!GO:0016202;regulation of striated muscle development;0.0052155810003835;57810!GO:0045026;plasma membrane fusion;0.0052155810003835;57810!GO:0048628;myoblast maturation;0.00612032464330717;57810!GO:0006944;membrane fusion;0.00612032464330717;57810!GO:0048627;myoblast development;0.00612032464330717;57810!GO:0001708;cell fate specification;0.00612032464330717;57810!GO:0007224;smoothened signaling pathway;0.00695410800051134;57810!GO:0045445;myoblast differentiation;0.00838218375061634;57810!GO:0045597;positive regulation of cell differentiation;0.0100805347066236;57810!GO:0042692;muscle cell differentiation;0.0119213280008766;57810!GO:0048741;skeletal muscle fiber development;0.0119213280008766;57810!GO:0048747;muscle fiber development;0.0119213280008766;57810!GO:0051094;positive regulation of developmental process;0.0122406492866143;57810!GO:0048469;cell maturation;0.0125309413645578;57810!GO:0021700;developmental maturation;0.0147396854358664;57810!GO:0007519;skeletal muscle development;0.0147464343760843;57810!GO:0045165;cell fate commitment;0.0149016600010957;57810!GO:0014706;striated muscle development;0.0174807934628238;57810!GO:0045595;regulation of cell differentiation;0.0211106850015523;57810!GO:0007517;muscle development;0.0220863889301954;57810!GO:0009986;cell surface;0.0237655784500233;57810!GO:0048598;embryonic morphogenesis;0.0249602805018353;57810!GO:0016337;cell-cell adhesion;0.0249963329050638;57810!GO:0016044;membrane organization and biogenesis;0.0271256779707445;57810!GO:0050793;regulation of developmental process;0.0289001890930341;57810!GO:0009790;embryonic development;0.0489782501506602;57810!
|ontology_enrichment_celltype=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0002323!4.69e-09!37;UBERON:0004458!4.69e-09!37;UBERON:0000468!1.26e-08!333;UBERON:0003886!2.40e-08!38;UBERON:0002553!1.09e-07!39
|tfbs_overrepresentation_for_novel_motifs=0.641384,0.128156,0.612053,0.688265,0.483253,0.704257,0.803568,0.370124,0.381467,0.949265,0.755749,0.790506,0.37041,0.81685,0.502646,0,1.02248,0.473993,0.352304,1.2676,1.39891,0.197567,0.815872,0.481455,0.620553,0.846564,1.62441,0.727368,0.535752,0.290745,0.711848,1.12823,0.471365,0.854272,0.503207,0.623685,0.460474,0.786577,0.434783,0.40068,0.478558,0.717547,0.185353,0.504971,0.66772,0.675898,0.938241,0.744678,0.162985,0.539131,1.0041,0.875451,0.771943,1.2746,1.29252,0.82458,1.35435,0.776619,0.331485,0.822375,1.10737,0.885556,0.39557,0.992216,0.8366,1.03484,1.43193,1.78579,1.1025,1.63712,0.590754,0.377213,0.205546,1.32691,0.323563,0.834514,0.318792,0.926147,1.08947,0.575233,1.75112,1.04072,0.884013,0.362446,1.20828,0.11855,0.129654,0.290918,0.943446,1.94914,1.50286,1.21342,1.14153,0.490141,0.430015,0.409166,0.367176,1.14445,0.938512,1.34553,0.460566,1.12793,1.25667,1.00472,1.00361,0.717061,1.06633,0.740267,0.580757,0.57247,0.633483,1.25851,0.576517,0.7614,1.51002,0.476467,0.869142,0.692434,1.02384,1.15537,1.33244,0.970073,0.848526,0.925183,1.56496,1.09333,0.812403,1.13449,1.43038,0.493609,1.23918,0.680176,1.40022,0.839311,1.53196,0.195549,0.650785,0.719099,1.482,2.31884,1.91709,1.43673,0.861473,1.1391,0.996781,0.718046,0.941555,2.27909,0.653418,0.485304,0.293812,0.184289,1.27621,0.416214,0.838313,1.35996,0.87653,0.516549,1.54212,0.650472,1.49167,1.20739,1.09379,0.630949,0.993294,0.830321,0.459159,0.788782,0.0824127
|tfbs_overrepresentation_jaspar=MA0003.1;0.0356887,MA0004.1;0.6888,MA0006.1;0.497533,MA0007.1;0.672186,MA0009.1;1.15569,MA0014.1;0.276754,MA0017.1;0.528196,MA0019.1;0.964875,MA0024.1;1.11019,MA0025.1;1.39562,MA0027.1;2.81824,MA0028.1;0.509589,MA0029.1;1.08753,MA0030.1;1.09438,MA0031.1;1.05719,MA0038.1;0.846479,MA0040.1;1.16866,MA0041.1;0.604221,MA0042.1;0.589368,MA0043.1;1.25564,MA0046.1;1.1929,MA0048.1;0.735223,MA0050.1;0.731539,MA0051.1;0.856094,MA0052.1;1.17701,MA0055.1;0.125758,MA0056.1;0,MA0057.1;1.29714,MA0058.1;0.581673,MA0059.1;0.59559,MA0060.1;0.403071,MA0061.1;0.438628,MA0063.1;0,MA0066.1;0.834648,MA0067.1;1.50873,MA0068.1;0.256913,MA0069.1;1.17737,MA0070.1;1.16732,MA0071.1;0.73062,MA0072.1;1.15853,MA0073.1;0.0140887,MA0074.1;0.795862,MA0076.1;0.550092,MA0077.1;1.13603,MA0078.1;0.891476,MA0081.1;0.621611,MA0083.1;1.25482,MA0084.1;1.84013,MA0087.1;1.21037,MA0088.1;0.201215,MA0089.1;0,MA0090.1;0.650768,MA0091.1;0.703314,MA0092.1;0.651119,MA0093.1;0.519148,MA0095.1;0,MA0098.1;0,MA0100.1;0.783305,MA0101.1;1.47308,MA0103.1;1.33576,MA0105.1;0.313353,MA0106.1;0.899777,MA0107.1;2.27141,MA0108.2;0.989014,MA0109.1;0,MA0111.1;0.666525,MA0113.1;0.869608,MA0114.1;0.43587,MA0115.1;1.25852,MA0116.1;0.497293,MA0117.1;1.22527,MA0119.1;0.606338,MA0122.1;1.24573,MA0124.1;1.45461,MA0125.1;1.37907,MA0130.1;0,MA0131.1;0.960068,MA0132.1;0,MA0133.1;0,MA0135.1;1.29308,MA0136.1;0.817395,MA0139.1;0.365453,MA0140.1;0.78318,MA0141.1;0.563066,MA0142.1;1.04199,MA0143.1;0.887119,MA0144.1;0.439506,MA0145.1;0.21199,MA0146.1;0.0944145,MA0147.1;0.453952,MA0148.1;0.706718,MA0149.1;0.611881,MA0062.2;0.319836,MA0035.2;0.788288,MA0039.2;0.0959929,MA0138.2;0.951653,MA0002.2;0.965577,MA0137.2;0.559766,MA0104.2;0.386166,MA0047.2;0.845655,MA0112.2;0.211985,MA0065.2;0.212467,MA0150.1;0.67206,MA0151.1;0,MA0152.1;0.84577,MA0153.1;1.31015,MA0154.1;0.263609,MA0155.1;0.650923,MA0156.1;0.549102,MA0157.1;1.0083,MA0158.1;0,MA0159.1;0.465802,MA0160.1;0.71003,MA0161.1;0,MA0162.1;0.346529,MA0163.1;0.0996272,MA0164.1;0.817786,MA0080.2;0.534538,MA0018.2;0.828253,MA0099.2;0.944966,MA0079.2;0.300141,MA0102.2;1.8929,MA0258.1;0.419871,MA0259.1;0.441366,MA0442.1;0
}}

Latest revision as of 18:37, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr9:35231167..35231174,+p3@Cdon
Mm9::chr9:35232460..35232473,+p@chr9:35232460..35232473
+
Mm9::chr9:35232504..35232525,+p@chr9:35232504..35232525
+
Mm9::chr9:35232543..35232569,+p@chr9:35232543..35232569
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0045663positive regulation of myoblast differentiation0.00372541500027393
GO:0010172embryonic body morphogenesis0.00372541500027393
GO:0010171body morphogenesis0.00372541500027393
GO:0014902myotube differentiation0.00372541500027393
GO:0000768syncytium formation by plasma membrane fusion0.00372541500027393
GO:0007520myoblast fusion0.00372541500027393
GO:0045661regulation of myoblast differentiation0.00372541500027393
GO:0006949syncytium formation0.00372541500027393
GO:0016202regulation of striated muscle development0.0052155810003835
GO:0045026plasma membrane fusion0.0052155810003835
GO:0048628myoblast maturation0.00612032464330717
GO:0006944membrane fusion0.00612032464330717
GO:0048627myoblast development0.00612032464330717
GO:0001708cell fate specification0.00612032464330717
GO:0007224smoothened signaling pathway0.00695410800051134
GO:0045445myoblast differentiation0.00838218375061634
GO:0045597positive regulation of cell differentiation0.0100805347066236
GO:0042692muscle cell differentiation0.0119213280008766
GO:0048741skeletal muscle fiber development0.0119213280008766
GO:0048747muscle fiber development0.0119213280008766
GO:0051094positive regulation of developmental process0.0122406492866143
GO:0048469cell maturation0.0125309413645578
GO:0021700developmental maturation0.0147396854358664
GO:0007519skeletal muscle development0.0147464343760843
GO:0045165cell fate commitment0.0149016600010957
GO:0014706striated muscle development0.0174807934628238
GO:0045595regulation of cell differentiation0.0211106850015523
GO:0007517muscle development0.0220863889301954
GO:0009986cell surface0.0237655784500233
GO:0048598embryonic morphogenesis0.0249602805018353
GO:0016337cell-cell adhesion0.0249963329050638
GO:0016044membrane organization and biogenesis0.0271256779707445
GO:0050793regulation of developmental process0.0289001890930341
GO:0009790embryonic development0.0489782501506602



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
body cavity4.69e-0937
body cavity or lining4.69e-0937
multi-cellular organism1.26e-08333
body cavity precursor2.40e-0838
anatomical cavity1.09e-0739


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.0356887
MA0004.10.6888
MA0006.10.497533
MA0007.10.672186
MA0009.11.15569
MA0014.10.276754
MA0017.10.528196
MA0019.10.964875
MA0024.11.11019
MA0025.11.39562
MA0027.12.81824
MA0028.10.509589
MA0029.11.08753
MA0030.11.09438
MA0031.11.05719
MA0038.10.846479
MA0040.11.16866
MA0041.10.604221
MA0042.10.589368
MA0043.11.25564
MA0046.11.1929
MA0048.10.735223
MA0050.10.731539
MA0051.10.856094
MA0052.11.17701
MA0055.10.125758
MA0056.10
MA0057.11.29714
MA0058.10.581673
MA0059.10.59559
MA0060.10.403071
MA0061.10.438628
MA0063.10
MA0066.10.834648
MA0067.11.50873
MA0068.10.256913
MA0069.11.17737
MA0070.11.16732
MA0071.10.73062
MA0072.11.15853
MA0073.10.0140887
MA0074.10.795862
MA0076.10.550092
MA0077.11.13603
MA0078.10.891476
MA0081.10.621611
MA0083.11.25482
MA0084.11.84013
MA0087.11.21037
MA0088.10.201215
MA0089.10
MA0090.10.650768
MA0091.10.703314
MA0092.10.651119
MA0093.10.519148
MA0095.10
MA0098.10
MA0100.10.783305
MA0101.11.47308
MA0103.11.33576
MA0105.10.313353
MA0106.10.899777
MA0107.12.27141
MA0108.20.989014
MA0109.10
MA0111.10.666525
MA0113.10.869608
MA0114.10.43587
MA0115.11.25852
MA0116.10.497293
MA0117.11.22527
MA0119.10.606338
MA0122.11.24573
MA0124.11.45461
MA0125.11.37907
MA0130.10
MA0131.10.960068
MA0132.10
MA0133.10
MA0135.11.29308
MA0136.10.817395
MA0139.10.365453
MA0140.10.78318
MA0141.10.563066
MA0142.11.04199
MA0143.10.887119
MA0144.10.439506
MA0145.10.21199
MA0146.10.0944145
MA0147.10.453952
MA0148.10.706718
MA0149.10.611881
MA0062.20.319836
MA0035.20.788288
MA0039.20.0959929
MA0138.20.951653
MA0002.20.965577
MA0137.20.559766
MA0104.20.386166
MA0047.20.845655
MA0112.20.211985
MA0065.20.212467
MA0150.10.67206
MA0151.10
MA0152.10.84577
MA0153.11.31015
MA0154.10.263609
MA0155.10.650923
MA0156.10.549102
MA0157.11.0083
MA0158.10
MA0159.10.465802
MA0160.10.71003
MA0161.10
MA0162.10.346529
MA0163.10.0996272
MA0164.10.817786
MA0080.20.534538
MA0018.20.828253
MA0099.20.944966
MA0079.20.300141
MA0102.21.8929
MA0258.10.419871
MA0259.10.441366
MA0442.10
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