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Revision as of 13:41, 27 June 2012

Name:reticulum trabeculare
Definition:"a fenestrated endothelial-like tissue situated at the intersection of the cornea and the iris[GO]. The trabecular meshwork is an area of tissue in the eye located around the base of the cornea, near the ciliary body, and is responsible for draining the aqueous humor from the eye via the anterior chamber (the chamber on the front of the eye covered by the cornea). The tissue is spongy and lined by trabeculocytes; it allows fluid to drain into a set of tubes called Schlemm's canal flowing into the blood system[WP]. A porelike structure surrounding the entire circumference of the anterior chamber through which aqueous humor circulates to the canal of Schlemm.[GAID] the pore-like structure surrounding the entire circumference of the anterior chamber through which aqueous humor circulates[MP]." [GO:0002930, MP:0005203, Wikipedia:Trabecular_meshwork]
Xrefs:
links:

BTO:0001605
EFO:0003077
EV:0100352
GAID:897
[ Gray870.png Gray870.png]
MESH:A.09.371.060.932

ncithesaurus:Trabecular_Meshwork
Synonyms: "cribiform ligament" RELATED [Wikipedia:Trabecular_meshwork]
"Hueck's ligament" RELATED [BTO:0001605]
"iridis" RELATED [Wikipedia:Trabecular_meshwork]
"ligamentum peactin-tum iridis" RELATED [Wikipedia:Trabecular_meshwork]
"ligamentum pectinatum" RELATED [Wikipedia:Trabecular_meshwork]
"ligamentum pectinatum anguli iridocornealis" RELATED [BTO:0001605]
"ligamentum pectinatum iridis" RELATED [Wikipedia:Trabecular_meshwork]
"pectinate ligament" RELATED [BTO:0001605]
"pectinate ligament of iris" RELATED [BTO:0001605]
"reticulum trabeculare sclerae" RELATED LATIN [Wikipedia:Trabecular_meshwork]
"scleral trabeculae" RELATED [Wikipedia:Trabecular_meshwork]
"scleral trabecular" RELATED [Wikipedia:Trabecular_meshwork]
"scleral trabecule" RELATED [Wikipedia:Trabecular_meshwork]
"scribiform ligament" RELATED [Wikipedia:Trabecular_meshwork]
"trabecular mesh" RELATED [Wikipedia:Trabecular_meshwork]
"trabecular meshwork" RELATED [BTO:0001605, GO:0002930]
"trabecular meshwork of the eye" EXACT [Wikipedia:Trabecular_meshwork]
Comments:TODO check syns - ligaments
Alt_id: UBERON:0004028

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:UBERON:0000479(tissue),UBERON:0004121(ectoderm-derived structure)
part_of:UBERON:0000019(camera-type eye),UBERON:0003956(aqueous drainage system)



Children

part of:CL:0002367 (trabecular meshwork cell)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology


Human (Homo sapiens)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0005969 (reticulum trabeculare), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data


P-valueFFCPShort description
4.52e-50FFCP PHASE2:Hg19::chr4:111558887..111558892,-#_cf2c31ee72344e862f9ca5292a72f85cp14@PITX2
4.52e-50FFCP PHASE1:Hg19::chr4:111558887..111558892,-#_cf2c31ee72344e862f9ca5292a72f85cp14@PITX2
2.01e-40FFCP PHASE1:Hg19::chr6:105232902..105232908,-#_75368dd3e3406af7092ecb16fc997088p8@HACE1
2.01e-40FFCP PHASE2:Hg19::chr6:105232902..105232908,-#_75368dd3e3406af7092ecb16fc997088p8@HACE1
9.84e-37FFCP PHASE2:Hg19::chr19:10983098..10983110,+#_6a00914962c9f8ea968ca0ce7ee1d619p@chr19:10983098..10983110, +
9.84e-37FFCP PHASE1:Hg19::chr19:10983098..10983110,+#_6a00914962c9f8ea968ca0ce7ee1d619p@chr19:10983098..10983110, +
7.33e-32FFCP PHASE2:Hg19::chr6:50786479..50786490,+#_1a457ea6e2bc55c8b27aed755febf35ap6@TFAP2B
7.33e-32FFCP PHASE1:Hg19::chr6:50786479..50786490,+#_1a457ea6e2bc55c8b27aed755febf35ap6@TFAP2B
5.5e-31FFCP PHASE2:Hg19::chr4:111536662..111536674,-#_274d002644ce29132e40e041997260c2p3@ENST00000513690
5.5e-31FFCP PHASE1:Hg19::chr4:111536662..111536674,-#_274d002644ce29132e40e041997260c2p3@ENST00000513690
6.96e-30FFCP PHASE1:Hg19::chr3:129279438..129279448,-#_5719580bf7878bbd42e6973344bf9abcp17@PLXND1
6.96e-30FFCP PHASE2:Hg19::chr3:129279438..129279448,-#_5719580bf7878bbd42e6973344bf9abcp17@PLXND1
2.96e-29FFCP PHASE2:Hg19::chr6:50786631..50786635,+#_75b37e44cc1b8d47303b9e0b10ddcd4cp11@TFAP2B
2.96e-29FFCP PHASE1:Hg19::chr6:50786631..50786635,+#_75b37e44cc1b8d47303b9e0b10ddcd4cp11@TFAP2B
6.99e-29FFCP PHASE1:Hg19::chr1:153744081..153744096,+#_720d96b48f494d291589de186f5b6cb4p@chr1:153744081..153744096, +
6.99e-29FFCP PHASE2:Hg19::chr1:153744081..153744096,+#_720d96b48f494d291589de186f5b6cb4p@chr1:153744081..153744096, +
9.18e-26FFCP PHASE2:Hg19::chr11:61634768..61634777,+#_11c3626eb3f0c1086aa3b4b52b03bfb6p@chr11:61634768..61634777, +
9.18e-26FFCP PHASE1:Hg19::chr11:61634768..61634777,+#_11c3626eb3f0c1086aa3b4b52b03bfb6p@chr11:61634768..61634777, +
3.91e-25FFCP PHASE1:Hg19::chr6:50789737..50789746,+#_9af7ef0b8f74a1fec5e3083d6f479408p10@TFAP2B
3.91e-25FFCP PHASE2:Hg19::chr6:50789737..50789746,+#_9af7ef0b8f74a1fec5e3083d6f479408p10@TFAP2B
2.3e-22FFCP PHASE2:Hg19::chr8:60032478..60032492,+#_00a60c76a6cc377140a350c0ef67f21dp2@ENST00000517898, p2@uc003xty.1
2.3e-22FFCP PHASE1:Hg19::chr8:60032478..60032492,+#_00a60c76a6cc377140a350c0ef67f21dp2@ENST00000517898, p2@uc003xty.1
3.81e-21FFCP PHASE1:Hg19::chr6:41562324..41562340,+#_79a14b966d2bb1d709d435f861b2b75bp16@FOXP4
3.81e-21FFCP PHASE2:Hg19::chr6:41562324..41562340,+#_79a14b966d2bb1d709d435f861b2b75bp16@FOXP4
4.66e-21FFCP PHASE2:Hg19::chr11:61634723..61634731,+#_c97be5bdc3ce3a07a0ee4b8e0aa4e865p@chr11:61634723..61634731, +
4.66e-21FFCP PHASE1:Hg19::chr11:61634723..61634731,+#_c97be5bdc3ce3a07a0ee4b8e0aa4e865p@chr11:61634723..61634731, +
1.7e-19FFCP PHASE1:Hg19::chr19:11306638..11306657,-#_1a7bb6bad5edb5fe1761c09dca531ed0p13@KANK2
1.7e-19FFCP PHASE2:Hg19::chr19:11306638..11306657,-#_1a7bb6bad5edb5fe1761c09dca531ed0p13@KANK2
3.16e-18FFCP PHASE1:Hg19::chr6:78171774..78171792,+#_f04bc53dec7054f0a2f20d8a7b739512p@chr6:78171774..78171792, +
3.16e-18FFCP PHASE2:Hg19::chr6:78171774..78171792,+#_f04bc53dec7054f0a2f20d8a7b739512p@chr6:78171774..78171792, +
6.82e-18FFCP PHASE1:Hg19::chr6:50787466..50787500,+#_f4ddfffeb9820ffc492016f29e9cae42p@chr6:50787466..50787500, +
6.82e-18FFCP PHASE2:Hg19::chr6:50787466..50787500,+#_f4ddfffeb9820ffc492016f29e9cae42p@chr6:50787466..50787500, +
8.24e-18FFCP PHASE2:Hg19::chr11:47279167..47279178,+#_62ac8600ec47d6867e2b569924579e20p10@NR1H3
8.24e-18FFCP PHASE1:Hg19::chr11:47279167..47279178,+#_62ac8600ec47d6867e2b569924579e20p10@NR1H3
1.27e-17FFCP PHASE1:Hg19::chr7:143079562..143079573,+#_e7d44ae954a92832db52948ed8b5ef8dp39@ZYX
1.27e-17FFCP PHASE2:Hg19::chr7:143079562..143079573,+#_e7d44ae954a92832db52948ed8b5ef8dp39@ZYX
1.46e-17FFCP PHASE1:Hg19::chr4:13379049..13379051,+#_a0ae288c1620cb08b046c6dd12c7ea88p@chr4:13379049..13379051, +
1.46e-17FFCP PHASE2:Hg19::chr4:13379049..13379051,+#_a0ae288c1620cb08b046c6dd12c7ea88p@chr4:13379049..13379051, +
1.88e-17FFCP PHASE2:Hg19::chr9:116327296..116327307,+#_cc3003927cc27fa42066c06f4a480d20p21@RGS3
1.88e-17FFCP PHASE1:Hg19::chr9:116327296..116327307,+#_cc3003927cc27fa42066c06f4a480d20p21@RGS3
6.47e-17FFCP PHASE2:Hg19::chr1:27269555..27269558,+#_bf3caf595491ab4e78dd9231e15ec219p@chr1:27269555..27269558, +
6.47e-17FFCP PHASE1:Hg19::chr1:27269555..27269558,+#_bf3caf595491ab4e78dd9231e15ec219p@chr1:27269555..27269558, +
1.45e-16FFCP PHASE1:Hg19::chr12:57522813..57522825,-#_cb2b27917dbb3f8fabe8c83905ed3bd4p10@STAT6
1.45e-16FFCP PHASE2:Hg19::chr12:57522813..57522825,-#_cb2b27917dbb3f8fabe8c83905ed3bd4p10@STAT6
2.33e-16FFCP PHASE1:Hg19::chr1:156677222..156677267,-#_ef803721e99fc1b35e1576d26ef6d511p@chr1:156677222..156677267, -
2.33e-16FFCP PHASE2:Hg19::chr1:156677222..156677267,-#_ef803721e99fc1b35e1576d26ef6d511p@chr1:156677222..156677267, -
3.77e-16FFCP PHASE1:Hg19::chr4:1167293..1167308,-#_9e06a6aa387206a405b9163d056117aap18@SPON2
3.77e-16FFCP PHASE2:Hg19::chr4:1167293..1167308,-#_9e06a6aa387206a405b9163d056117aap18@SPON2
1.78e-15FFCP PHASE1:Hg19::chr9:129376073..129376080,-#_1b93df182e5a61773a0ebf5c034ec3b6p2@ENST00000451449
1.78e-15FFCP PHASE2:Hg19::chr9:129376073..129376080,-#_1b93df182e5a61773a0ebf5c034ec3b6p2@ENST00000451449
4.8e-15FFCP PHASE1:Hg19::chr22:45898587..45898598,+#_475c70b78eac132dc551a415d8620cb1p13@FBLN1
4.8e-15FFCP PHASE2:Hg19::chr22:45898587..45898598,+#_475c70b78eac132dc551a415d8620cb1p13@FBLN1
9.41e-15FFCP PHASE2:Hg19::chr19:38878454..38878497,-#_7c2ead674e750cc757d0a06254dfc15dp1@GGN
9.41e-15FFCP PHASE1:Hg19::chr19:38878454..38878497,-#_7c2ead674e750cc757d0a06254dfc15dp1@GGN
4.04e-14FFCP PHASE2:Hg19::chr9:123165410..123165421,-#_bb722241a3f488e8d2fd5f524d7e1d85p14@CDK5RAP2
4.04e-14FFCP PHASE1:Hg19::chr9:123165410..123165421,-#_bb722241a3f488e8d2fd5f524d7e1d85p14@CDK5RAP2
6.62e-14FFCP PHASE1:Hg19::chr6:50786547..50786564,+#_74adb8cd661242df7c026e7621467ac8p3@TFAP2B
6.62e-14FFCP PHASE2:Hg19::chr6:50786547..50786564,+#_74adb8cd661242df7c026e7621467ac8p3@TFAP2B
7.57e-14FFCP PHASE2:Hg19::chr12:45904157..45904158,-#_43e7b35b1b861afc368d089554d4cd44p@chr12:45904157..45904158, -
7.57e-14FFCP PHASE1:Hg19::chr12:45904157..45904158,-#_43e7b35b1b861afc368d089554d4cd44p@chr12:45904157..45904158, -
1.37e-13FFCP PHASE1:Hg19::chr3:4722301..4722324,+#_5bf05dee805c849a625e1f19115291d5p@chr3:4722301..4722324, +
1.37e-13FFCP PHASE2:Hg19::chr3:4722301..4722324,+#_5bf05dee805c849a625e1f19115291d5p@chr3:4722301..4722324, +
1.54e-13FFCP PHASE2:Hg19::chr12:1609708..1609723,+#_07b4bac2a303a4915071d339e1c2b954p2@LOC100292680
1.54e-13FFCP PHASE1:Hg19::chr12:1609708..1609723,+#_07b4bac2a303a4915071d339e1c2b954p2@LOC100292680
1.55e-13FFCP PHASE2:Hg19::chrX:13792679..13792690,-#_381ffd2461a365f8a0ca54a7656104e6p@chrX:13792679..13792690, -
1.55e-13FFCP PHASE1:Hg19::chrX:13792679..13792690,-#_381ffd2461a365f8a0ca54a7656104e6p@chrX:13792679..13792690, -
1.75e-13FFCP PHASE1:Hg19::chr12:81102260..81102302,+#_d57d6f25e55fb1d542717193d7a0b967p@chr12:81102260..81102302, +
1.75e-13FFCP PHASE2:Hg19::chr12:81102260..81102302,+#_d57d6f25e55fb1d542717193d7a0b967p@chr12:81102260..81102302, +
4.17e-13FFCP PHASE1:Hg19::chr6:78171746..78171769,+#_3a8deec2fb6a92ad23b1387602823237p@chr6:78171746..78171769, +
4.17e-13FFCP PHASE2:Hg19::chr6:78171746..78171769,+#_3a8deec2fb6a92ad23b1387602823237p@chr6:78171746..78171769, +
4.47e-13FFCP PHASE1:Hg19::chr7:100425082..100425085,-#_fe5fd4f37f7096b9042a9881112c13abp6@EPHB4
4.47e-13FFCP PHASE2:Hg19::chr7:100425082..100425085,-#_fe5fd4f37f7096b9042a9881112c13abp6@EPHB4
5.2e-13FFCP PHASE2:Hg19::chr19:7580234..7580253,+#_fb41a4c5b9218ab7028ee0c414805e1ap@chr19:7580234..7580253, +
5.2e-13FFCP PHASE1:Hg19::chr19:7580234..7580253,+#_fb41a4c5b9218ab7028ee0c414805e1ap@chr19:7580234..7580253, +
5.73e-13FFCP PHASE2:Hg19::chr1:110625307..110625328,+#_fb1d20c3428f983ec9b24f90bb302ba9p1@ENST00000554808
5.73e-13FFCP PHASE1:Hg19::chr1:110625307..110625328,+#_fb1d20c3428f983ec9b24f90bb302ba9p1@ENST00000554808
7.57e-13FFCP PHASE1:Hg19::chr1:110613276..110613299,-#_85026689422d4d3ecf0e55518fd7bdd4p2@ALX3
7.57e-13FFCP PHASE2:Hg19::chr1:110613276..110613299,-#_85026689422d4d3ecf0e55518fd7bdd4p2@ALX3
1.28e-12FFCP PHASE1:Hg19::chr1:110613238..110613272,-#_e1467dd4452bddec689083ed23e765edp1@ALX3
1.28e-12FFCP PHASE2:Hg19::chr1:110613238..110613272,-#_e1467dd4452bddec689083ed23e765edp1@ALX3
1.29e-12FFCP PHASE1:Hg19::chr2:12246664..12246694,+#_d958f8fddd78086b058ac423cb8c787fp1@ENST00000449986
1.29e-12FFCP PHASE2:Hg19::chr2:12246664..12246694,+#_d958f8fddd78086b058ac423cb8c787fp1@ENST00000449986
2.32e-12FFCP PHASE1:Hg19::chr16:54962394..54962407,+#_61dc49f7de2063fab733eaf92a2a2bd4p@chr16:54962394..54962407, +
2.32e-12FFCP PHASE1:Hg19::chr17:27052878..27052889,+#_61dc49f7de2063fab733eaf92a2a2bd4p@chr17:27052878..27052889, +
2.32e-12FFCP PHASE2:Hg19::chr16:54962394..54962407,+#_61dc49f7de2063fab733eaf92a2a2bd4p@chr16:54962394..54962407, +
2.32e-12FFCP PHASE2:Hg19::chr17:27052878..27052889,+#_61dc49f7de2063fab733eaf92a2a2bd4p@chr17:27052878..27052889, +
3.24e-12FFCP PHASE1:Hg19::chr1:201798251..201798253,+#_d3e6dfb5327f256b6992ce80ceec5104p5@IPO9
3.24e-12FFCP PHASE2:Hg19::chr2:71206252..71206265,+#_d3e6dfb5327f256b6992ce80ceec5104p8@ANKRD53
3.24e-12FFCP PHASE2:Hg19::chr1:201798251..201798253,+#_d3e6dfb5327f256b6992ce80ceec5104p5@IPO9
3.24e-12FFCP PHASE1:Hg19::chr2:71206252..71206265,+#_d3e6dfb5327f256b6992ce80ceec5104p8@ANKRD53
3.56e-12FFCP PHASE1:Hg19::chr6:50786571..50786590,+#_4b542841a6e360d965f81ef84c564a24p2@TFAP2B
3.56e-12FFCP PHASE2:Hg19::chr6:50786571..50786590,+#_4b542841a6e360d965f81ef84c564a24p2@TFAP2B
3.84e-12FFCP PHASE1:Hg19::chr11:19619705..19619737,+#_2c44bb9f7251034bf6dfac772d74332ap@chr11:19619705..19619737, +
3.84e-12FFCP PHASE2:Hg19::chr11:19619705..19619737,+#_2c44bb9f7251034bf6dfac772d74332ap@chr11:19619705..19619737, +
3.92e-12FFCP PHASE1:Hg19::chr1:68851155..68851158,+#_44e657b624ef28e15e67e8d7e9d51329p@chr1:68851155..68851158, +
3.92e-12FFCP PHASE2:Hg19::chr1:68851155..68851158,+#_44e657b624ef28e15e67e8d7e9d51329p@chr1:68851155..68851158, +
4.16e-12FFCP PHASE1:Hg19::chr2:26972981..26973006,+#_4f711fd84c3005bebf5e2a690bf98285p@chr2:26972981..26973006, +
4.16e-12FFCP PHASE2:Hg19::chr2:26972981..26973006,+#_4f711fd84c3005bebf5e2a690bf98285p@chr2:26972981..26973006, +
4.39e-12FFCP PHASE1:Hg19::chr6:111888474..111888487,-#_f3e7d98f2314a94826af133fa69b0951p11@TRAF3IP2
4.39e-12FFCP PHASE2:Hg19::chr6:111888474..111888487,-#_f3e7d98f2314a94826af133fa69b0951p11@TRAF3IP2