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|ontology_enrichment_disease=DOID:299!4.19e-08!25
|ontology_enrichment_disease=DOID:299!4.19e-08!25
|ontology_enrichment_uberon=UBERON:0000160!1.00e-08!27;UBERON:0005631!2.43e-08!14;UBERON:0000158!2.43e-08!14;UBERON:0000464!7.92e-08!104;UBERON:0000058!1.72e-07!26;UBERON:0009773!1.93e-07!12;UBERON:0001231!1.93e-07!12;UBERON:0004810!1.93e-07!12;UBERON:0005409!3.97e-07!35;UBERON:0004119!4.32e-07!169;UBERON:0000925!4.32e-07!169;UBERON:0006595!4.32e-07!169;UBERON:0001007!5.40e-07!155;UBERON:0001555!5.40e-07!155;UBERON:0007026!5.40e-07!155
|ontology_enrichment_uberon=UBERON:0000160!1.00e-08!27;UBERON:0005631!2.43e-08!14;UBERON:0000158!2.43e-08!14;UBERON:0000464!7.92e-08!104;UBERON:0000058!1.72e-07!26;UBERON:0009773!1.93e-07!12;UBERON:0001231!1.93e-07!12;UBERON:0004810!1.93e-07!12;UBERON:0005409!3.97e-07!35;UBERON:0004119!4.32e-07!169;UBERON:0000925!4.32e-07!169;UBERON:0006595!4.32e-07!169;UBERON:0001007!5.40e-07!155;UBERON:0001555!5.40e-07!155;UBERON:0007026!5.40e-07!155
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}}
}}

Revision as of 19:44, 8 August 2012


Full id: C4108_amniotic_serous_small_chorionic_colon_adenocarcinoma_tenocyte



Phase1 CAGE Peaks

Hg19::chr22:46880166..46880186,-p@chr22:46880166..46880186
-
Hg19::chr7:73149405..73149421,+p1@ABHD11-AS1
Hg19::chr7:73149424..73149445,+p@chr7:73149424..73149445
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen
kidney tubule cell1.93e-0712
nephron tubule epithelial cell1.93e-0712
kidney cell5.77e-0718
kidney epithelial cell5.77e-0718
Uber Anatomy
Ontology termp-valuen
intestine1.00e-0827
extraembryonic membrane2.43e-0814
membranous layer2.43e-0814
anatomical space7.92e-08104
duct1.72e-0726
renal tubule1.93e-0712
nephron tubule1.93e-0712
nephron tubule epithelium1.93e-0712
gastrointestinal system3.97e-0735
endoderm-derived structure4.32e-07169
endoderm4.32e-07169
presumptive endoderm4.32e-07169
digestive system5.40e-07155
digestive tract5.40e-07155
primitive gut5.40e-07155
Disease
Ontology termp-valuen
adenocarcinoma4.19e-0825


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.