MCL coexpression mm9:415

Phase1 CAGE Peaks

	Short description
Mm9::chr10:42069681..42069682,+	p@chr10:42069681..42069682 +
Mm9::chr11:54012860..54012868,+	p1@ENSMUST00000081565
Mm9::chr13:74543835..74543844,+	p4@Ftl1
Mm9::chr17:7183242..7183261,+	p1@Rnaset2a p1@Rnaset2b
Mm9::chr17:87477595..87477607,+	p1@ENSMUST00000090731
Mm9::chr2:175868413..175868426,+	p1@Gm6710 p2@Gm14391
Mm9::chr2:35195857..35195886,+	p1@ENSMUST00000120770
Mm9::chr2:90213339..90213368,+	p@chr2:90213339..90213368 +
Mm9::chr3:155177407..155177427,+	p@chr3:155177407..155177427 +
Mm9::chr4:32138685..32138706,+	p1@ENSMUST00000118472
Mm9::chr5:123516216..123516243,+	p1@ENSMUST00000119611
Mm9::chrM:5319..5333,+	p1@COX1
Mm9::chrM:5722..5731,+	p6@uc009vey.1
Mm9::chrM:6239..6248,+	p@chrM:6239..6248 +
Mm9::chrM:7024..7052,+	p1@uc009vez.1
Mm9::chrM:8600..8616,+	p1@COX3
Mm9::chrM:8618..8619,+	p@chrM:8618..8619 +
Mm9::chrM:8962..8969,+	p@chrM:8962..8969 +

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0004666	prostaglandin-endoperoxide synthase activity	3.89009571904692e-06
GO:0046457	prostanoid biosynthetic process	3.62916469088e-05
GO:0001516	prostaglandin biosynthetic process	3.62916469088e-05
GO:0006693	prostaglandin metabolic process	6.06367358332774e-05
GO:0006692	prostanoid metabolic process	6.06367358332774e-05
GO:0030216	keratinocyte differentiation	0.000153134506745507
GO:0046456	icosanoid biosynthetic process	0.000153134506745507
GO:0006690	icosanoid metabolic process	0.000186301976999254
GO:0005506	iron ion binding	0.000186301976999254
GO:0004601	peroxidase activity	0.000186301976999254
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	0.000186301976999254
GO:0008217	regulation of blood pressure	0.000252154800350663
GO:0006979	response to oxidative stress	0.000295315933460486
GO:0051213	dioxygenase activity	0.000428520525538543
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	0.000428520525538543
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	0.000428520525538543
GO:0006633	fatty acid biosynthetic process	0.000534209130421097
GO:0016053	organic acid biosynthetic process	0.000535274786417597
GO:0046394	carboxylic acid biosynthetic process	0.000535274786417597
GO:0065008	regulation of biological quality	0.000782351827223182
GO:0008015	blood circulation	0.000784158683003003
GO:0003013	circulatory system process	0.000784158683003003
GO:0020037	heme binding	0.000981680819807866
GO:0046906	tetrapyrrole binding	0.000981680819807866
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	0.00119512058405546
GO:0005792	microsome	0.00172063762134358
GO:0042598	vesicular fraction	0.0017444587094867
GO:0006631	fatty acid metabolic process	0.00174688220475826
GO:0032787	monocarboxylic acid metabolic process	0.00298215665127091
GO:0008610	lipid biosynthetic process	0.00353457034005823
GO:0006118	electron transport	0.00602689689208029
GO:0042640	anagen	0.00716661879967187
GO:0008199	ferric iron binding	0.00716661879967187
GO:0048820	hair follicle maturation	0.00900010873064759
GO:0006091	generation of precursor metabolites and energy	0.00900010873064759
GO:0042221	response to chemical stimulus	0.00935044996864805
GO:0005624	membrane fraction	0.00966493200881029
GO:0019752	carboxylic acid metabolic process	0.00966493200881029
GO:0006082	organic acid metabolic process	0.00966493200881029
GO:0000267	cell fraction	0.0115122084135358
GO:0044255	cellular lipid metabolic process	0.0116806601661614
GO:0055072	iron ion homeostasis	0.0131847305268283
GO:0006879	cellular iron ion homeostasis	0.0131847305268283
GO:0006629	lipid metabolic process	0.0141700903658431
GO:0006826	iron ion transport	0.0141700903658431
GO:0046914	transition metal ion binding	0.0164872840486589
GO:0005783	endoplasmic reticulum	0.0180704133387437
GO:0022404	molting cycle process	0.0188732725824415
GO:0001942	hair follicle development	0.0188732725824415
GO:0022405	hair cycle process	0.0188732725824415
GO:0006950	response to stress	0.0191356268445424
GO:0042633	hair cycle	0.0191356268445424
GO:0042303	molting cycle	0.0191356268445424
GO:0016491	oxidoreductase activity	0.0194942515739056
GO:0048589	developmental growth	0.0205754867926271
GO:0044249	cellular biosynthetic process	0.0230587317209953
GO:0000041	transition metal ion transport	0.0239699767016792
GO:0044444	cytoplasmic part	0.0306017770355671
GO:0043169	cation binding	0.0329474628057774
GO:0021700	developmental maturation	0.0356308322922689
GO:0030005	cellular di-, tri-valent inorganic cation homeostasis	0.0361361919428277
GO:0008544	epidermis development	0.0361361919428277
GO:0055066	di-, tri-valent inorganic cation homeostasis	0.0361361919428277
GO:0009058	biosynthetic process	0.0361361919428277
GO:0007398	ectoderm development	0.036474269846928
GO:0030003	cellular cation homeostasis	0.0366419168396595
GO:0046872	metal ion binding	0.0366419168396595
GO:0055080	cation homeostasis	0.0369180792714478
GO:0043167	ion binding	0.0377095642421444
GO:0015674	di-, tri-valent inorganic cation transport	0.0444824625843817
GO:0055082	cellular chemical homeostasis	0.0468260302002133
GO:0006873	cellular ion homeostasis	0.0468260302002133
GO:0065007	biological regulation	0.0468260302002133

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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