MCL coexpression mm9:415
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr10:42069681..42069682,+ | p@chr10:42069681..42069682 + |
| Mm9::chr11:54012860..54012868,+ | p1@ENSMUST00000081565 |
| Mm9::chr13:74543835..74543844,+ | p4@Ftl1 |
| Mm9::chr17:7183242..7183261,+ | p1@Rnaset2a p1@Rnaset2b |
| Mm9::chr17:87477595..87477607,+ | p1@ENSMUST00000090731 |
| Mm9::chr2:175868413..175868426,+ | p1@Gm6710 p2@Gm14391 |
| Mm9::chr2:35195857..35195886,+ | p1@ENSMUST00000120770 |
| Mm9::chr2:90213339..90213368,+ | p@chr2:90213339..90213368 + |
| Mm9::chr3:155177407..155177427,+ | p@chr3:155177407..155177427 + |
| Mm9::chr4:32138685..32138706,+ | p1@ENSMUST00000118472 |
| Mm9::chr5:123516216..123516243,+ | p1@ENSMUST00000119611 |
| Mm9::chrM:5319..5333,+ | p1@COX1 |
| Mm9::chrM:5722..5731,+ | p6@uc009vey.1 |
| Mm9::chrM:6239..6248,+ | p@chrM:6239..6248 + |
| Mm9::chrM:7024..7052,+ | p1@uc009vez.1 |
| Mm9::chrM:8600..8616,+ | p1@COX3 |
| Mm9::chrM:8618..8619,+ | p@chrM:8618..8619 + |
| Mm9::chrM:8962..8969,+ | p@chrM:8962..8969 + |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0004666 | prostaglandin-endoperoxide synthase activity | 3.89009571904692e-06 |
| GO:0046457 | prostanoid biosynthetic process | 3.62916469088e-05 |
| GO:0001516 | prostaglandin biosynthetic process | 3.62916469088e-05 |
| GO:0006693 | prostaglandin metabolic process | 6.06367358332774e-05 |
| GO:0006692 | prostanoid metabolic process | 6.06367358332774e-05 |
| GO:0030216 | keratinocyte differentiation | 0.000153134506745507 |
| GO:0046456 | icosanoid biosynthetic process | 0.000153134506745507 |
| GO:0006690 | icosanoid metabolic process | 0.000186301976999254 |
| GO:0005506 | iron ion binding | 0.000186301976999254 |
| GO:0004601 | peroxidase activity | 0.000186301976999254 |
| GO:0016684 | oxidoreductase activity, acting on peroxide as acceptor | 0.000186301976999254 |
| GO:0008217 | regulation of blood pressure | 0.000252154800350663 |
| GO:0006979 | response to oxidative stress | 0.000295315933460486 |
| GO:0051213 | dioxygenase activity | 0.000428520525538543 |
| GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | 0.000428520525538543 |
| GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen | 0.000428520525538543 |
| GO:0006633 | fatty acid biosynthetic process | 0.000534209130421097 |
| GO:0016053 | organic acid biosynthetic process | 0.000535274786417597 |
| GO:0046394 | carboxylic acid biosynthetic process | 0.000535274786417597 |
| GO:0065008 | regulation of biological quality | 0.000782351827223182 |
| GO:0008015 | blood circulation | 0.000784158683003003 |
| GO:0003013 | circulatory system process | 0.000784158683003003 |
| GO:0020037 | heme binding | 0.000981680819807866 |
| GO:0046906 | tetrapyrrole binding | 0.000981680819807866 |
| GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | 0.00119512058405546 |
| GO:0005792 | microsome | 0.00172063762134358 |
| GO:0042598 | vesicular fraction | 0.0017444587094867 |
| GO:0006631 | fatty acid metabolic process | 0.00174688220475826 |
| GO:0032787 | monocarboxylic acid metabolic process | 0.00298215665127091 |
| GO:0008610 | lipid biosynthetic process | 0.00353457034005823 |
| GO:0006118 | electron transport | 0.00602689689208029 |
| GO:0042640 | anagen | 0.00716661879967187 |
| GO:0008199 | ferric iron binding | 0.00716661879967187 |
| GO:0048820 | hair follicle maturation | 0.00900010873064759 |
| GO:0006091 | generation of precursor metabolites and energy | 0.00900010873064759 |
| GO:0042221 | response to chemical stimulus | 0.00935044996864805 |
| GO:0005624 | membrane fraction | 0.00966493200881029 |
| GO:0019752 | carboxylic acid metabolic process | 0.00966493200881029 |
| GO:0006082 | organic acid metabolic process | 0.00966493200881029 |
| GO:0000267 | cell fraction | 0.0115122084135358 |
| GO:0044255 | cellular lipid metabolic process | 0.0116806601661614 |
| GO:0055072 | iron ion homeostasis | 0.0131847305268283 |
| GO:0006879 | cellular iron ion homeostasis | 0.0131847305268283 |
| GO:0006629 | lipid metabolic process | 0.0141700903658431 |
| GO:0006826 | iron ion transport | 0.0141700903658431 |
| GO:0046914 | transition metal ion binding | 0.0164872840486589 |
| GO:0005783 | endoplasmic reticulum | 0.0180704133387437 |
| GO:0022404 | molting cycle process | 0.0188732725824415 |
| GO:0001942 | hair follicle development | 0.0188732725824415 |
| GO:0022405 | hair cycle process | 0.0188732725824415 |
| GO:0006950 | response to stress | 0.0191356268445424 |
| GO:0042633 | hair cycle | 0.0191356268445424 |
| GO:0042303 | molting cycle | 0.0191356268445424 |
| GO:0016491 | oxidoreductase activity | 0.0194942515739056 |
| GO:0048589 | developmental growth | 0.0205754867926271 |
| GO:0044249 | cellular biosynthetic process | 0.0230587317209953 |
| GO:0000041 | transition metal ion transport | 0.0239699767016792 |
| GO:0044444 | cytoplasmic part | 0.0306017770355671 |
| GO:0043169 | cation binding | 0.0329474628057774 |
| GO:0021700 | developmental maturation | 0.0356308322922689 |
| GO:0030005 | cellular di-, tri-valent inorganic cation homeostasis | 0.0361361919428277 |
| GO:0008544 | epidermis development | 0.0361361919428277 |
| GO:0055066 | di-, tri-valent inorganic cation homeostasis | 0.0361361919428277 |
| GO:0009058 | biosynthetic process | 0.0361361919428277 |
| GO:0007398 | ectoderm development | 0.036474269846928 |
| GO:0030003 | cellular cation homeostasis | 0.0366419168396595 |
| GO:0046872 | metal ion binding | 0.0366419168396595 |
| GO:0055080 | cation homeostasis | 0.0369180792714478 |
| GO:0043167 | ion binding | 0.0377095642421444 |
| GO:0015674 | di-, tri-valent inorganic cation transport | 0.0444824625843817 |
| GO:0055082 | cellular chemical homeostasis | 0.0468260302002133 |
| GO:0006873 | cellular ion homeostasis | 0.0468260302002133 |
| GO:0065007 | biological regulation | 0.0468260302002133 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| mucosa | 1.22e-16 | 15 |
| connective tissue | 1.84e-16 | 46 |
| intestinal mucosa | 1.06e-13 | 13 |
| anatomical wall | 1.06e-13 | 13 |
| wall of intestine | 1.06e-13 | 13 |
| gastrointestinal system mucosa | 1.06e-13 | 13 |
| simple columnar epithelium | 2.42e-13 | 11 |
| epithelium of mucosa | 1.34e-11 | 9 |
| gastrointestinal system epithelium | 1.34e-11 | 9 |
| intestinal epithelium | 1.34e-11 | 9 |
| organ component layer | 5.93e-09 | 24 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.012764 |
| MA0004.1 | 0.191582 |
| MA0006.1 | 0.0854592 |
| MA0007.1 | 0.181021 |
| MA0009.1 | 0.5557 |
| MA0014.1 | 0.00614145 |
| MA0017.1 | 0.328722 |
| MA0019.1 | 0.394308 |
| MA0024.1 | 0.516087 |
| MA0025.1 | 0.773017 |
| MA0027.1 | 2.16618 |
| MA0028.1 | 0.0910441 |
| MA0029.1 | 0.496599 |
| MA0030.1 | 0.502474 |
| MA0031.1 | 0.470779 |
| MA0038.1 | 0.815918 |
| MA0040.1 | 0.567108 |
| MA0041.1 | 0.140298 |
| MA0042.1 | 0.412259 |
| MA0043.1 | 0.644695 |
| MA0046.1 | 0.58854 |
| MA0048.1 | 0.0629374 |
| MA0050.1 | 0.219748 |
| MA0051.1 | 0.309072 |
| MA0052.1 | 0.574473 |
| MA0055.1 | 0.0237024 |
| MA0056.1 | 0 |
| MA0057.1 | 0.0109462 |
| MA0058.1 | 0.127732 |
| MA0059.1 | 0.421089 |
| MA0060.1 | 0.180016 |
| MA0061.1 | 0.060618 |
| MA0063.1 | 0 |
| MA0066.1 | 0.293002 |
| MA0067.1 | 0.879099 |
| MA0068.1 | 0.0116947 |
| MA0069.1 | 0.574784 |
| MA0070.1 | 0.565924 |
| MA0071.1 | 0.219128 |
| MA0072.1 | 0.558195 |
| MA0073.1 | 7.65122e-05 |
| MA0074.1 | 0.264633 |
| MA0076.1 | 0.110983 |
| MA0077.1 | 0.538513 |
| MA0078.1 | 0.336143 |
| MA0081.1 | 0.150322 |
| MA0083.1 | 0.643958 |
| MA0084.1 | 1.1979 |
| MA0087.1 | 0.604077 |
| MA0088.1 | 0.0282169 |
| MA0089.1 | 0 |
| MA0090.1 | 0.167748 |
| MA0091.1 | 0.582275 |
| MA0092.1 | 0.502322 |
| MA0093.1 | 0.0955883 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.255651 |
| MA0101.1 | 0.435524 |
| MA0103.1 | 0.106139 |
| MA0105.1 | 0.0968542 |
| MA0106.1 | 0.342589 |
| MA0107.1 | 0.686139 |
| MA0108.2 | 0.413973 |
| MA0109.1 | 0 |
| MA0111.1 | 0.177475 |
| MA0113.1 | 0.319332 |
| MA0114.1 | 0.470969 |
| MA0115.1 | 0.647296 |
| MA0116.1 | 0.288992 |
| MA0117.1 | 0.617392 |
| MA0119.1 | 0.141504 |
| MA0122.1 | 0.635764 |
| MA0124.1 | 0.828115 |
| MA0125.1 | 0.757653 |
| MA0130.1 | 0 |
| MA0131.1 | 0.390422 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 0.67864 |
| MA0136.1 | 0.280269 |
| MA0139.1 | 0.0357525 |
| MA0140.1 | 0.255562 |
| MA0141.1 | 0.11774 |
| MA0142.1 | 0.457961 |
| MA0143.1 | 0.332773 |
| MA0144.1 | 0.219807 |
| MA0145.1 | 0.0329339 |
| MA0146.1 | 0.00234189 |
| MA0147.1 | 0.236435 |
| MA0148.1 | 0.203219 |
| MA0149.1 | 0.144679 |
| MA0062.2 | 0.0237736 |
| MA0035.2 | 0.259203 |
| MA0039.2 | 0.000301019 |
| MA0138.2 | 0.383644 |
| MA0002.2 | 0.338271 |
| MA0137.2 | 0.371067 |
| MA0104.2 | 0.162663 |
| MA0047.2 | 0.301217 |
| MA0112.2 | 0.00604704 |
| MA0065.2 | 0.0973139 |
| MA0150.1 | 0.180943 |
| MA0151.1 | 0 |
| MA0152.1 | 0.301303 |
| MA0153.1 | 0.694211 |
| MA0154.1 | 0.162966 |
| MA0155.1 | 0.430598 |
| MA0156.1 | 0.110475 |
| MA0157.1 | 0.429861 |
| MA0158.1 | 0 |
| MA0159.1 | 0.0715631 |
| MA0160.1 | 0.205397 |
| MA0161.1 | 0 |
| MA0162.1 | 0.00359771 |
| MA0163.1 | 0.00283249 |
| MA0164.1 | 1.40306 |
| MA0080.2 | 0.103116 |
| MA0018.2 | 0.288261 |
| MA0099.2 | 0.37828 |
| MA0079.2 | 2.7993e-08 |
| MA0102.2 | 1.24942 |
| MA0258.1 | 0.0535937 |
| MA0259.1 | 0.221921 |
| MA0442.1 | 0 |
