MCL coexpression mm9:2259

Phase1 CAGE Peaks

	Short description
Mm9::chr19:36811146..36811160,-	p1@Ppp1r3c
Mm9::chr3:116510969..116510979,-	p10@Agl
Mm9::chr4:99602049..99602137,+	p1@Pgm2
Mm9::chr4:99602138..99602149,+	p2@Pgm2

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0044262	cellular carbohydrate metabolic process	0.000108753326171585
GO:0005975	carbohydrate metabolic process	0.000108753326171585
GO:0005977	glycogen metabolic process	0.000108753326171585
GO:0006073	glucan metabolic process	0.000108753326171585
GO:0006112	energy reserve metabolic process	0.000111309702332188
GO:0005976	polysaccharide metabolic process	0.000144385332420965
GO:0044264	cellular polysaccharide metabolic process	0.000144385332420965
GO:0015980	energy derivation by oxidation of organic compounds	0.00025051326069894
GO:0004133	glycogen debranching enzyme activity	0.000949615588305118
GO:0004614	phosphoglucomutase activity	0.00341805423570848
GO:0008599	protein phosphatase type 1 regulator activity	0.00388393972196418
GO:0016868	intramolecular transferase activity, phosphotransferases	0.00592127149155579
GO:0006091	generation of precursor metabolites and energy	0.00592127149155579
GO:0009250	glucan biosynthetic process	0.00626402959732651
GO:0005978	glycogen biosynthetic process	0.00626402959732651
GO:0033692	cellular polysaccharide biosynthetic process	0.00954259841460151
GO:0000271	polysaccharide biosynthetic process	0.00954259841460151
GO:0016866	intramolecular transferase activity	0.0137483130670221
GO:0019888	protein phosphatase regulator activity	0.0143697388261853
GO:0019208	phosphatase regulator activity	0.0149286012982054
GO:0043284	biopolymer biosynthetic process	0.0263609252893713
GO:0016051	carbohydrate biosynthetic process	0.0305588804811419
GO:0006006	glucose metabolic process	0.0358548525668646
GO:0019318	hexose metabolic process	0.0454764530594491
GO:0005996	monosaccharide metabolic process	0.0454764530594491
GO:0016853	isomerase activity	0.0478532756546137
GO:0043170	macromolecule metabolic process	0.0478532756546137

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
epithelial tube	2.57e-12	47
digestive tract diverticulum	1.13e-08	23
sac	1.13e-08	23
liver	1.34e-08	22
epithelial sac	1.34e-08	22
digestive gland	1.34e-08	22
epithelium of foregut-midgut junction	1.34e-08	22
anatomical boundary	1.34e-08	22
hepatobiliary system	1.34e-08	22
foregut-midgut junction	1.34e-08	22
hepatic diverticulum	1.34e-08	22
liver primordium	1.34e-08	22
septum transversum	1.34e-08	22
liver bud	1.34e-08	22
exocrine gland	7.28e-08	25
exocrine system	7.28e-08	25
tube	4.98e-07	114

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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