UBERON:0002328
From FANTOM5_SSTAR
| Name: | notochord | ||
|---|---|---|---|
| Namespace: | FANTOM | ||
| Definition: | "Avascular multi-tissue structure composed of large vacuolated epithelial cells (chordablasts) and perichordal fibrous tissue[VSAO]. The notochord is an elongate, rod-like, skeletal structure dorsal to the gut tube and ventral to the nerve cord. The notochord should not be confused with the backbone or vertebral column of most adult vertebrates. The notochord appears early in embryogeny and plays an important role in promoting or organizing the embryonic development of nearby structures. In most adult chordates the notochord disappears or becomes highly modified. In some non-vertebrate chordates and fishes the notochord persists as a laterally flexible but incompressible skeletal rod that prevents telescopic collapse of the body during swimming[TOLWEB]." https://github.com/cmungall/uberon/issues/25, ISBN:0815318960, NLM:notochord, VSAO:0000032, Wikipedia:Notochord, ZFIN:curator | ||
| Xrefs: |
| ||
| Synonyms: |
"embryonic notocord" EXACT [] "notochorda" RELATED LATIN [Wikipedia:Notochord] "notocord" EXACT [ZFA:0000135] | ||
| Comments: | Development notes: In between vertebra the notochord becomes the nucleus pulposus, under it degenerates, and at anterior end in some species its tissue merges with some of the cranial bones.. Some organisms retain a post-embryonic notochord | ||
| Alt_id: | UBERON:FMA_85521-XAO_0000055-ZFA_0000135 | ||
| Subset: |
uberon_slim vertebrate_core |
Gray19_with_color.png]
200px-Gray19_with_color.png]
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | UBERON:0000481(multi-tissue structure),UBERON:0004120(mesoderm-derived structure),UBERON:0004121(ectoderm-derived structure) |
|---|---|
| develops_from: | UBERON:0004880(chordamesoderm),UBERON:0006267(notochordal plate) |
| part_of: | UBERON:0011137(axial skeletal system) |
Children
| develops from: | UBERON:0002242 (nucleus pulposus) |
|---|
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0002328 (notochord), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
| P-value | FFCP | Short description |
|---|---|---|
| 8.26e-98 | FFCP PHASE1:Hg19::chr3:174737010..174737023,+#_8a3240178a0d3906890ccc27ea164d27 | p@chr3:174737010..174737023, + |
| 8.26e-98 | FFCP PHASE2:Hg19::chr3:174737010..174737023,+#_8a3240178a0d3906890ccc27ea164d27 | p@chr3:174737010..174737023, + |
| 3.03e-84 | FFCP PHASE1:Hg19::chr20:21687193..21687206,+#_00b47d821e1a6dc7e783a7b2add9e886 | p4@PAX1 |
| 3.03e-84 | FFCP PHASE2:Hg19::chr20:21687193..21687206,+#_00b47d821e1a6dc7e783a7b2add9e886 | p4@PAX1 |
| 2.39e-66 | FFCP PHASE2:Hg19::chr9:33028063..33028067,-#_3e14fe85d457466589b197d26ad9628c | p@chr9:33028063..33028067, - |
| 2.39e-66 | FFCP PHASE1:Hg19::chr9:33028063..33028067,-#_3e14fe85d457466589b197d26ad9628c | p@chr9:33028063..33028067, - |
| 5.46e-60 | FFCP PHASE2:Hg19::chr5:30104176..30104187,-#_98bf58ac96501c398cdd8e3c7aed412a | p@chr5:30104176..30104187, - |
| 5.46e-60 | FFCP PHASE1:Hg19::chr5:30104176..30104187,-#_98bf58ac96501c398cdd8e3c7aed412a | p@chr5:30104176..30104187, - |
| 9.77e-45 | FFCP PHASE2:Hg19::chr2:241987807..241987808,+#_57c80b7ad5d56b23687297361d075373 | p22@SNED1 |
| 9.77e-45 | FFCP PHASE1:Hg19::chr2:241987807..241987808,+#_57c80b7ad5d56b23687297361d075373 | p22@SNED1 |
| 6.64e-41 | FFCP PHASE2:Hg19::chr2:242004292..242004308,+#_50c6d9ea9ea76b1b8b187518537c0ff6 | p15@SNED1 |
| 6.64e-41 | FFCP PHASE1:Hg19::chr2:242004292..242004308,+#_50c6d9ea9ea76b1b8b187518537c0ff6 | p15@SNED1 |
| 1.31e-40 | FFCP PHASE1:Hg19::chr1:19811132..19811155,-#_c0aab570daf6a340ea01333cf74b8d14 | p20@CAPZB |
| 1.31e-40 | FFCP PHASE2:Hg19::chr1:19811132..19811155,-#_c0aab570daf6a340ea01333cf74b8d14 | p20@CAPZB |
| 1.8e-38 | FFCP PHASE2:Hg19::chr2:12248310..12248334,-#_561c38e42f64585cc1abe8bd5a7938e8 | p@chr2:12248310..12248334, - |
| 1.8e-38 | FFCP PHASE1:Hg19::chr2:12248310..12248334,-#_561c38e42f64585cc1abe8bd5a7938e8 | p@chr2:12248310..12248334, - |
| 2.75e-34 | FFCP PHASE1:Hg19::chr14:61190754..61190776,-#_18cc461ea4499ef7468c5dcaa36189b4 | p6@SIX4 |
| 2.75e-34 | FFCP PHASE2:Hg19::chr14:61190754..61190776,-#_18cc461ea4499ef7468c5dcaa36189b4 | p6@SIX4 |
| 5.96e-34 | FFCP PHASE1:Hg19::chr4:88727274..88727278,+#_ec727959a65888726dd01a6e37d111ce | p@chr4:88727274..88727278, + |
| 5.96e-34 | FFCP PHASE1:Hg19::chr13:51101468..51101499,-#_ec727959a65888726dd01a6e37d111ce | p1@ENST00000428276 |
| 5.96e-34 | FFCP PHASE2:Hg19::chr13:51101468..51101499,-#_ec727959a65888726dd01a6e37d111ce | p1@ENST00000428276 |
| 5.96e-34 | FFCP PHASE1:Hg19::chr11:93468399..93468405,-#_ec727959a65888726dd01a6e37d111ce | p19@TAF1D, p1@SNORA40 |
| 5.96e-34 | FFCP PHASE2:Hg19::chr4:88727274..88727278,+#_ec727959a65888726dd01a6e37d111ce | p@chr4:88727274..88727278, + |
| 5.96e-34 | FFCP PHASE2:Hg19::chr11:93468399..93468405,-#_ec727959a65888726dd01a6e37d111ce | p19@TAF1D, p1@SNORA40 |
| 2.09e-33 | FFCP PHASE1:Hg19::chr4:13546130..13546145,-#_0234ad872f1b2f208d3472faeff2cca1 | p4@NKX3-2 |
| 2.09e-33 | FFCP PHASE2:Hg19::chr4:13546130..13546145,-#_0234ad872f1b2f208d3472faeff2cca1 | p4@NKX3-2 |
| 4.01e-31 | FFCP PHASE1:Hg19::chr7:18832913..18832946,+#_180f08942a01f302e2676936cb10e2cd | p19@HDAC9 |
| 4.01e-31 | FFCP PHASE2:Hg19::chr7:18832913..18832946,+#_180f08942a01f302e2676936cb10e2cd | p19@HDAC9 |
| 1.98e-30 | FFCP PHASE1:Hg19::chr2:241897125..241897142,-#_749191faec073636787b41e8ec1ec2c5 | p@chr2:241897125..241897142, - |
| 1.98e-30 | FFCP PHASE2:Hg19::chr2:241897125..241897142,-#_749191faec073636787b41e8ec1ec2c5 | p@chr2:241897125..241897142, - |
| 4.84e-30 | FFCP PHASE2:Hg19::chr3:80727046..80727051,-#_39b752a1f265d331b20b884524e3313c | p@chr3:80727046..80727051, - |
| 4.84e-30 | FFCP PHASE1:Hg19::chr3:80727046..80727051,-#_39b752a1f265d331b20b884524e3313c | p@chr3:80727046..80727051, - |
| 7.46e-30 | FFCP PHASE1:Hg19::chr7:158224707..158224729,-#_048fad19a32c7c03b71306683f78acdb | p@chr7:158224707..158224729, - |
| 7.46e-30 | FFCP PHASE2:Hg19::chr7:158224707..158224729,-#_048fad19a32c7c03b71306683f78acdb | p@chr7:158224707..158224729, - |
| 1.48e-29 | FFCP PHASE1:Hg19::chr1:65888177..65888194,+#_eb97d37fee927423bddc4c5937fc5bb0 | p@chr1:65888177..65888194, + |
| 1.48e-29 | FFCP PHASE2:Hg19::chr1:65888177..65888194,+#_eb97d37fee927423bddc4c5937fc5bb0 | p@chr1:65888177..65888194, + |
| 2.72e-28 | FFCP PHASE1:Hg19::chr14:100848311..100848321,+#_9a455a8d30f4041fcb6346b5777debca | p5@WDR25 |
| 2.72e-28 | FFCP PHASE2:Hg19::chr14:100848311..100848321,+#_9a455a8d30f4041fcb6346b5777debca | p5@WDR25 |
| 3.26e-27 | FFCP PHASE1:Hg19::chr1:78695274..78695292,+#_3873de80edea86ea51f2e815f1c3f9f4 | p1@MGC27382 |
| 3.26e-27 | FFCP PHASE2:Hg19::chr1:78695274..78695292,+#_3873de80edea86ea51f2e815f1c3f9f4 | p1@MGC27382 |
| 6.92e-27 | FFCP PHASE1:Hg19::chr1:19778678..19778689,-#_cf92f71908f7a5ca4716451f8582a6ae | p@chr1:19778678..19778689, - |
| 6.92e-27 | FFCP PHASE2:Hg19::chr1:19778678..19778689,-#_cf92f71908f7a5ca4716451f8582a6ae | p@chr1:19778678..19778689, - |
| 1.46e-26 | FFCP PHASE2:Hg19::chr7:18832834..18832859,+#_4aa387d562cfa025ee6fc1ebfc66e31d | p18@HDAC9 |
| 1.46e-26 | FFCP PHASE1:Hg19::chr7:18832834..18832859,+#_4aa387d562cfa025ee6fc1ebfc66e31d | p18@HDAC9 |
| 1.74e-26 | FFCP PHASE1:Hg19::chr4:156129991..156130013,+#_c2acf486de8f694aed859a96854c483e | p2@NPY2R |
| 1.74e-26 | FFCP PHASE2:Hg19::chr4:156129991..156130013,+#_c2acf486de8f694aed859a96854c483e | p2@NPY2R |
| 7.41e-26 | FFCP PHASE1:Hg19::chr14:61113228..61113233,-#_70057bc12ed127e0aabe4730e2d9badc | p@chr14:61113228..61113233, - |
| 7.41e-26 | FFCP PHASE2:Hg19::chr14:61113228..61113233,-#_70057bc12ed127e0aabe4730e2d9badc | p@chr14:61113228..61113233, - |
| 2.04e-25 | FFCP PHASE2:Hg19::chr7:27212374..27212387,-#_6e09eca32f3aabd1523d20ef7cf285c6 | p12@HOXA10 |
| 2.04e-25 | FFCP PHASE1:Hg19::chr7:27212374..27212387,-#_6e09eca32f3aabd1523d20ef7cf285c6 | p12@HOXA10 |
| 6.22e-25 | FFCP PHASE1:Hg19::chr14:23574186..23574212,-#_54e28f53917ae1dc027aedcffd46f378 | p1@uc010aki.1 |
| 6.22e-25 | FFCP PHASE2:Hg19::chr14:23574186..23574212,-#_54e28f53917ae1dc027aedcffd46f378 | p1@uc010aki.1 |
| 9.49e-25 | FFCP PHASE2:Hg19::chr20:21686317..21686350,+#_49a50482c07e783223bea7c6de2d4beb | p1@PAX1 |
| 9.49e-25 | FFCP PHASE1:Hg19::chr20:21686317..21686350,+#_49a50482c07e783223bea7c6de2d4beb | p1@PAX1 |
| 4.58e-24 | FFCP PHASE2:Hg19::chr5:140887761..140887777,+#_4affc2abef7a76e561aa59785b55c03f | p@chr5:140887761..140887777, + |
| 4.58e-24 | FFCP PHASE1:Hg19::chr5:140887761..140887777,+#_4affc2abef7a76e561aa59785b55c03f | p@chr5:140887761..140887777, + |
| 5.35e-24 | FFCP PHASE2:Hg19::chr20:21686290..21686311,+#_295fc94342614cf105e312e8c8d7eff7 | p2@PAX1 |
| 5.35e-24 | FFCP PHASE1:Hg19::chr20:21686290..21686311,+#_295fc94342614cf105e312e8c8d7eff7 | p2@PAX1 |
| 8.55e-24 | FFCP PHASE2:Hg19::chr7:18832759..18832786,+#_516bf2545c0f628d14786b65c365ea89 | p16@HDAC9 |
| 8.55e-24 | FFCP PHASE1:Hg19::chr7:18832759..18832786,+#_516bf2545c0f628d14786b65c365ea89 | p16@HDAC9 |
| 2.01e-23 | FFCP PHASE2:Hg19::chr4:77068930..77068959,-#_da0363a228d2389cf78cc7bd4d852914 | p4@NUP54 |
| 2.01e-23 | FFCP PHASE1:Hg19::chr4:77068930..77068959,-#_da0363a228d2389cf78cc7bd4d852914 | p4@NUP54 |
| 2.28e-23 | FFCP PHASE2:Hg19::chr4:13546632..13546662,-#_73cd600376c33c8f2923808404d54d62 | p1@NKX3-2 |
| 2.28e-23 | FFCP PHASE1:Hg19::chr4:13546632..13546662,-#_73cd600376c33c8f2923808404d54d62 | p1@NKX3-2 |
| 3.27e-23 | FFCP PHASE1:Hg19::chr14:23574164..23574179,-#_ba2e7c86eac00bd2025393ff885f70cc | p3@uc010aki.1 |
| 3.27e-23 | FFCP PHASE2:Hg19::chr14:23574164..23574179,-#_ba2e7c86eac00bd2025393ff885f70cc | p3@uc010aki.1 |
| 1.25e-22 | FFCP PHASE2:Hg19::chr1:78695343..78695353,+#_4c2df3e4e5275379ce07e696563b65a9 | p2@ENST00000413519 |
| 1.25e-22 | FFCP PHASE1:Hg19::chr1:78695343..78695353,+#_4c2df3e4e5275379ce07e696563b65a9 | p2@ENST00000413519 |
| 1.46e-22 | FFCP PHASE1:Hg19::chr9:123239747..123239765,-#_217ecd4f2e0f468e4f6e505ea7e4ddef | p12@CDK5RAP2 |
| 1.46e-22 | FFCP PHASE2:Hg19::chr9:123239747..123239765,-#_217ecd4f2e0f468e4f6e505ea7e4ddef | p12@CDK5RAP2 |
| 9.47e-22 | FFCP PHASE1:Hg19::chr1:171076859..171076870,+#_ff05c6131f4dfcd2c9b2a00c6b8b846f | p@chr1:171076859..171076870, + |
| 9.47e-22 | FFCP PHASE2:Hg19::chr1:171076859..171076870,+#_ff05c6131f4dfcd2c9b2a00c6b8b846f | p@chr1:171076859..171076870, + |
| 1.35e-21 | FFCP PHASE2:Hg19::chr7:100202784..100202796,-#_b3933814a97729b98dd1e740637f25a5 | p@chr7:100202784..100202796, - |
| 1.35e-21 | FFCP PHASE1:Hg19::chr7:100202784..100202796,-#_b3933814a97729b98dd1e740637f25a5 | p@chr7:100202784..100202796, - |
| 3.83e-21 | FFCP PHASE1:Hg19::chr14:37126814..37126834,+#_f9a4d5452b130f38c2bca9f3227db7bb | p4@PAX9 |
| 3.83e-21 | FFCP PHASE2:Hg19::chr14:37126814..37126834,+#_f9a4d5452b130f38c2bca9f3227db7bb | p4@PAX9 |
| 4.02e-21 | FFCP PHASE1:Hg19::chr3:176765178..176765190,-#_87abf25145586a1c404a66fb7947be1e | p@chr3:176765178..176765190, - |
| 4.02e-21 | FFCP PHASE2:Hg19::chr3:176765178..176765190,-#_87abf25145586a1c404a66fb7947be1e | p@chr3:176765178..176765190, - |
| 4.06e-21 | FFCP PHASE1:Hg19::chr1:19810947..19810977,-#_e5219796d2af0293585526ed5bdf95e1 | p17@CAPZB |
| 4.06e-21 | FFCP PHASE2:Hg19::chr1:19810947..19810977,-#_e5219796d2af0293585526ed5bdf95e1 | p17@CAPZB |
| 5.43e-21 | FFCP PHASE1:Hg19::chr12:54422268..54422278,+#_f0efbbac3771c79d107c2ec9d69e2d7e | p8@HOXC6 |
| 5.43e-21 | FFCP PHASE2:Hg19::chr12:54422268..54422278,+#_f0efbbac3771c79d107c2ec9d69e2d7e | p8@HOXC6 |
| 4.94e-20 | FFCP PHASE1:Hg19::chr17:38613285..38613298,-#_2bbaed7afb43a98ea84e55a6f49f7546 | p@chr17:38613285..38613298, - |
| 4.94e-20 | FFCP PHASE2:Hg19::chr17:38613285..38613298,-#_2bbaed7afb43a98ea84e55a6f49f7546 | p@chr17:38613285..38613298, - |
| 9.53e-20 | FFCP PHASE2:Hg19::chr20:43343596..43343608,+#_ebd326f8730d0e5538a7318e0f10220a | p6@WISP2 |
| 9.53e-20 | FFCP PHASE1:Hg19::chr20:43343596..43343608,+#_ebd326f8730d0e5538a7318e0f10220a | p6@WISP2 |
| 1.46e-19 | FFCP PHASE2:Hg19::chr1:78958320..78958332,+#_c3ec549a7cc2c3f80bab8446b2b1c2b5 | p2@PTGFR |
| 1.46e-19 | FFCP PHASE1:Hg19::chr1:78958320..78958332,+#_c3ec549a7cc2c3f80bab8446b2b1c2b5 | p2@PTGFR |
| 2.04e-19 | FFCP PHASE2:Hg19::chr4:70707689..70707711,-#_a56caf97592aabe91c7b89a41ff2374e | p@chr4:70707689..70707711, - |
| 2.04e-19 | FFCP PHASE1:Hg19::chr4:70707689..70707711,-#_a56caf97592aabe91c7b89a41ff2374e | p@chr4:70707689..70707711, - |
| 3.75e-19 | FFCP PHASE1:Hg19::chr14:37126870..37126882,+#_8ad8f6a92828cc65b575801c464674fb | p1@ENST00000555639 |
| 3.75e-19 | FFCP PHASE2:Hg19::chr14:37126870..37126882,+#_8ad8f6a92828cc65b575801c464674fb | p1@ENST00000555639 |
| 4.68e-19 | FFCP PHASE1:Hg19::chr2:12246664..12246694,+#_246f088c29f41a083e52905124e4baa3 | p1@ENST00000449986 |
| 4.68e-19 | FFCP PHASE2:Hg19::chr2:12246664..12246694,+#_246f088c29f41a083e52905124e4baa3 | p1@ENST00000449986 |
| 1.04e-18 | FFCP PHASE2:Hg19::chr3:158390171..158390180,-#_9c15f3e7c82c66e01531c7bd22565226 | p3@LXN |
| 1.04e-18 | FFCP PHASE1:Hg19::chr3:158390171..158390180,-#_9c15f3e7c82c66e01531c7bd22565226 | p3@LXN |
| 5.12e-18 | FFCP PHASE2:Hg19::chr6:112375300..112375334,+#_dad1b191333330a3bb45e665f760d375 | p1@WISP3 |
| 5.12e-18 | FFCP PHASE1:Hg19::chr6:112375300..112375334,+#_dad1b191333330a3bb45e665f760d375 | p1@WISP3 |
| 9.14e-18 | FFCP PHASE2:Hg19::chr8:77595678..77595688,+#_a6e635053be9b60fd99dc11a00ea0bd2 | p9@ZFHX4 |
| 9.14e-18 | FFCP PHASE1:Hg19::chr8:77595678..77595688,+#_a6e635053be9b60fd99dc11a00ea0bd2 | p9@ZFHX4 |
Property "Property value" (as page type) with input value "UBPROP:0000001 "Avascular multi-tissue structure composed of large vacuolated epithelial cells (chordablasts) and perichordal fibrous tissue.[VSAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process., Property "Property value" (as page type) with input value "UBPROP:0000001 "Rod-like principal supportive element of the embryo and larva, present in the midline just ventral to the neural tube, and differentiating during the segmentation period to form large vacuolated epithelial cells and a surrounding a sheath of fibrous and elastic layers. Layering of the sheath may differ in structure, thickness and development among groups; in cypriniforms there are actually three very thin layers to the sheath. A functional, well developed notochord is present throughout life in certain basal fish groups but not in cypriniforms. Kimmel et al, 1995.[TAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process., Property "Property value" (as page type) with input value "UBPROP:0000001 "Slender rod of fibrous connective tissue surrounding a core of fluid-filled cells of mesodermal origin; it lies above the gut and directly beneath the spinal cord. The notochord is present during early development and in a few cases it is retained through life; however, usually the notochord is replaced by the vertebral column.[AAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process., Property "Property value" (as page type) with input value "UBPROP:0000002 "relationship type change: differentiates_from mesoderm (AAO:0000304) CHANGED TO: develops_from mesoderm (UBERON:0000926)[AAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.
