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UBERON:0002046

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Name:thyroid gland
Definition:"A two-lobed endocrine gland found in all vertebrates, located in front of and on either side of the trachea in humans, and producing various hormones, such as triiodothyronine and calcitonin[BTO]. A highly vascular endocrine gland consisting of two lobes, one on either side of the trachea, joined by a narrow isthmus; it produces the thyroid hormones which are concerned in regulating the metabolic rate of the body[GAID]." [BTO:0001379, GAID:465, Wikipedia:Thyroid]
Xrefs:
links:

AAO:0010544
BTO:0001379
EFO:0000861
EHDAA:2148
EHDAA:2975
EHDAA2:0002028
EMAPA:17068
EMAPA:18698
EMAPA:18827
EV:0100133
FMA:9603
GAID:465
galen:ThyroidGland
[1]
MA:0000129
MAT:0000081
MESH:A.06.407.900
MIAA:0000081
ncithesaurus:Thyroid_Gland
OpenCyc:Mx4rvVjLT5wpEbGdrcN5Y29ycA
SCTID:181117000
VHOG:0000418

XAO:0000162
Synonyms: "thyroid" EXACT []
Alt_id: UBERON:FMA_68805-FMA_9603-MA_0000129-MA_0000726-MIAA_0000081-XAO_0000162-ZFA_0001072
Subset: organ_slim
uberon_slim

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0002368(endocrine gland),UBERON:0002530(gland),UBERON:0004119(endoderm-derived structure)
develops_from:UBERON:0007689(thyroid diverticulum)
part_of:UBERON:0000949(endocrine system)



Children

derives from:FF:0010028 (human thyroid - adult sample),FF:0010060 (human thyroid - fetal sample)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

Human (Homo sapiens)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0002046 (thyroid gland), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
7.76e-118FFCP PHASE2:Hg19::chr8:11333461..11333472,-#_1987a6adcd9eb646d949d07d0bdca71bp@chr8:11333461..11333472, -
7.76e-118FFCP PHASE1:Hg19::chr8:11333461..11333472,-#_1987a6adcd9eb646d949d07d0bdca71bp@chr8:11333461..11333472, -
6.64e-89FFCP PHASE2:Hg19::chr8:11333445..11333459,-#_9ad73dfb8e3151378504da699925f2e7p@chr8:11333445..11333459, -
6.64e-89FFCP PHASE1:Hg19::chr8:11333445..11333459,-#_9ad73dfb8e3151378504da699925f2e7p@chr8:11333445..11333459, -
3.18e-79FFCP PHASE2:Hg19::chr14:36645825..36645840,-#_5eb7332b0d7e48332de68978eccad587p5@ENST00000556013
3.18e-79FFCP PHASE1:Hg19::chr14:36645825..36645840,-#_5eb7332b0d7e48332de68978eccad587p5@ENST00000556013
3.49e-79FFCP PHASE1:Hg19::chr8:133900431..133900436,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133900431..133900436, +
3.49e-79FFCP PHASE1:Hg19::chr8:134107312..134107315,+#_c3acdbdab95ff7e7ff9785f331e9ff61p46@TG
3.49e-79FFCP PHASE1:Hg19::chr21:39644214..39644219,+#_c3acdbdab95ff7e7ff9785f331e9ff61p21@KCNJ15
3.49e-79FFCP PHASE2:Hg19::chr14:21560489..21560506,-#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr14:21560489..21560506, -
3.49e-79FFCP PHASE1:Hg19::chr8:133885307..133885312,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133885307..133885312, +
3.49e-79FFCP PHASE2:Hg19::chr2:1417430..1417444,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr2:1417430..1417444, +
3.49e-79FFCP PHASE1:Hg19::chr8:133980132..133980143,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133980132..133980143, +
3.49e-79FFCP PHASE1:Hg19::chr7:107301406..107301418,+#_c3acdbdab95ff7e7ff9785f331e9ff61p5@SLC26A4
3.49e-79FFCP PHASE2:Hg19::chr16:66420861..66420868,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr16:66420861..66420868, +
3.49e-79FFCP PHASE1:Hg19::chr2:1457477..1457487,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr2:1457477..1457487, +
3.49e-79FFCP PHASE2:Hg19::chr8:133900431..133900436,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133900431..133900436, +
3.49e-79FFCP PHASE1:Hg19::chr8:133895057..133895065,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133895057..133895065, +
3.49e-79FFCP PHASE2:Hg19::chr14:67998625..67998628,-#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr14:67998625..67998628, -
3.49e-79FFCP PHASE1:Hg19::chr8:133899413..133899418,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133899413..133899418, +
3.49e-79FFCP PHASE1:Hg19::chr4:88047429..88047437,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr4:88047429..88047437, +
3.49e-79FFCP PHASE2:Hg19::chr8:133980132..133980143,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133980132..133980143, +
3.49e-79FFCP PHASE2:Hg19::chr8:133882027..133882038,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133882027..133882038, +
3.49e-79FFCP PHASE2:Hg19::chr21:39644214..39644219,+#_c3acdbdab95ff7e7ff9785f331e9ff61p21@KCNJ15
3.49e-79FFCP PHASE2:Hg19::chr8:133894780..133894789,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133894780..133894789, +
3.49e-79FFCP PHASE2:Hg19::chr15:64421903..64421920,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr15:64421903..64421920, +
3.49e-79FFCP PHASE1:Hg19::chr14:81421428..81421431,+#_c3acdbdab95ff7e7ff9785f331e9ff61p11@TSHR
3.49e-79FFCP PHASE1:Hg19::chr2:1417430..1417444,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr2:1417430..1417444, +
3.49e-79FFCP PHASE2:Hg19::chr8:134107327..134107332,+#_c3acdbdab95ff7e7ff9785f331e9ff61p29@TG
3.49e-79FFCP PHASE2:Hg19::chr8:133899413..133899418,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133899413..133899418, +
3.49e-79FFCP PHASE2:Hg19::chr4:88047429..88047437,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr4:88047429..88047437, +
3.49e-79FFCP PHASE2:Hg19::chr8:133961114..133961122,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133961114..133961122, +
3.49e-79FFCP PHASE1:Hg19::chr8:133981730..133981736,+#_c3acdbdab95ff7e7ff9785f331e9ff61p38@TG
3.49e-79FFCP PHASE1:Hg19::chr16:66420861..66420868,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr16:66420861..66420868, +
3.49e-79FFCP PHASE2:Hg19::chr2:134788853..134788858,-#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr2:134788853..134788858, -
3.49e-79FFCP PHASE2:Hg19::chr1:36771641..36771644,+#_c3acdbdab95ff7e7ff9785f331e9ff61p11@SH3D21
3.49e-79FFCP PHASE2:Hg19::chr8:133953595..133953600,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133953595..133953600, +
3.49e-79FFCP PHASE1:Hg19::chr8:133882027..133882038,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133882027..133882038, +
3.49e-79FFCP PHASE2:Hg19::chr8:133981730..133981736,+#_c3acdbdab95ff7e7ff9785f331e9ff61p38@TG
3.49e-79FFCP PHASE1:Hg19::chr8:133894780..133894789,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133894780..133894789, +
3.49e-79FFCP PHASE2:Hg19::chr2:1457500..1457511,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr2:1457500..1457511, +
3.49e-79FFCP PHASE1:Hg19::chr8:133899244..133899254,-#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133899244..133899254, -
3.49e-79FFCP PHASE1:Hg19::chr8:133961114..133961122,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133961114..133961122, +
3.49e-79FFCP PHASE1:Hg19::chr8:134107327..134107332,+#_c3acdbdab95ff7e7ff9785f331e9ff61p29@TG
3.49e-79FFCP PHASE1:Hg19::chr2:134788853..134788858,-#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr2:134788853..134788858, -
3.49e-79FFCP PHASE2:Hg19::chr8:133899244..133899254,-#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133899244..133899254, -
3.49e-79FFCP PHASE1:Hg19::chr1:36771641..36771644,+#_c3acdbdab95ff7e7ff9785f331e9ff61p11@SH3D21
3.49e-79FFCP PHASE1:Hg19::chr8:133953595..133953600,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133953595..133953600, +
3.49e-79FFCP PHASE1:Hg19::chr2:1457500..1457511,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr2:1457500..1457511, +
3.49e-79FFCP PHASE2:Hg19::chr8:134145709..134145716,+#_c3acdbdab95ff7e7ff9785f331e9ff61p18@TG
3.49e-79FFCP PHASE2:Hg19::chr8:133895164..133895167,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133895164..133895167, +
3.49e-79FFCP PHASE1:Hg19::chr8:133898957..133898963,-#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133898957..133898963, -
3.49e-79FFCP PHASE1:Hg19::chr8:133900307..133900325,-#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133900307..133900325, -
3.49e-79FFCP PHASE2:Hg19::chr2:1426812..1426834,+#_c3acdbdab95ff7e7ff9785f331e9ff61p5@TPO
3.49e-79FFCP PHASE2:Hg19::chr6:43837226..43837237,-#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr6:43837226..43837237, -
3.49e-79FFCP PHASE2:Hg19::chr18:24321747..24321752,-#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr18:24321747..24321752, -
3.49e-79FFCP PHASE2:Hg19::chr8:133898957..133898963,-#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133898957..133898963, -
3.49e-79FFCP PHASE1:Hg19::chr8:134145709..134145716,+#_c3acdbdab95ff7e7ff9785f331e9ff61p18@TG
3.49e-79FFCP PHASE1:Hg19::chr8:133895164..133895167,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133895164..133895167, +
3.49e-79FFCP PHASE2:Hg19::chr8:133898734..133898737,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133898734..133898737, +
3.49e-79FFCP PHASE2:Hg19::chr8:133900307..133900325,-#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133900307..133900325, -
3.49e-79FFCP PHASE2:Hg19::chr2:1459933..1459941,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr2:1459933..1459941, +
3.49e-79FFCP PHASE2:Hg19::chr14:81421428..81421431,+#_c3acdbdab95ff7e7ff9785f331e9ff61p11@TSHR
3.49e-79FFCP PHASE1:Hg19::chr2:1426812..1426834,+#_c3acdbdab95ff7e7ff9785f331e9ff61p5@TPO
3.49e-79FFCP PHASE2:Hg19::chr2:1440068..1440076,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr2:1440068..1440076, +
3.49e-79FFCP PHASE1:Hg19::chr6:43837226..43837237,-#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr6:43837226..43837237, -
3.49e-79FFCP PHASE1:Hg19::chr18:24321747..24321752,-#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr18:24321747..24321752, -
3.49e-79FFCP PHASE2:Hg19::chr8:133885414..133885420,-#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133885414..133885420, -
3.49e-79FFCP PHASE1:Hg19::chr8:133898734..133898737,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133898734..133898737, +
3.49e-79FFCP PHASE1:Hg19::chr8:133981694..133981700,+#_c3acdbdab95ff7e7ff9785f331e9ff61p35@TG
3.49e-79FFCP PHASE1:Hg19::chr7:107301447..107301451,+#_c3acdbdab95ff7e7ff9785f331e9ff61p23@SLC26A4
3.49e-79FFCP PHASE2:Hg19::chr8:11333494..11333497,-#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:11333494..11333497, -
3.49e-79FFCP PHASE1:Hg19::chr2:1459933..1459941,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr2:1459933..1459941, +
3.49e-79FFCP PHASE2:Hg19::chr8:134145732..134145736,+#_c3acdbdab95ff7e7ff9785f331e9ff61p27@TG
3.49e-79FFCP PHASE2:Hg19::chr8:133895195..133895206,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133895195..133895206, +
3.49e-79FFCP PHASE2:Hg19::chr8:133981694..133981700,+#_c3acdbdab95ff7e7ff9785f331e9ff61p35@TG
3.49e-79FFCP PHASE2:Hg19::chr7:107301447..107301451,+#_c3acdbdab95ff7e7ff9785f331e9ff61p23@SLC26A4
3.49e-79FFCP PHASE1:Hg19::chr2:1440068..1440076,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr2:1440068..1440076, +
3.49e-79FFCP PHASE1:Hg19::chr8:133899004..133899013,-#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133899004..133899013, -
3.49e-79FFCP PHASE2:Hg19::chr8:133978809..133978829,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133978809..133978829, +
3.49e-79FFCP PHASE2:Hg19::chr8:133898904..133898911,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133898904..133898911, +
3.49e-79FFCP PHASE1:Hg19::chr8:133900339..133900344,-#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133900339..133900344, -
3.49e-79FFCP PHASE2:Hg19::chr8:134108463..134108470,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:134108463..134108470, +
3.49e-79FFCP PHASE1:Hg19::chr8:133885414..133885420,-#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133885414..133885420, -
3.49e-79FFCP PHASE2:Hg19::chr2:1426850..1426859,+#_c3acdbdab95ff7e7ff9785f331e9ff61p10@TPO
3.49e-79FFCP PHASE2:Hg19::chr8:133899004..133899013,-#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133899004..133899013, -
3.49e-79FFCP PHASE1:Hg19::chr8:134145732..134145736,+#_c3acdbdab95ff7e7ff9785f331e9ff61p27@TG
3.49e-79FFCP PHASE1:Hg19::chr15:64421903..64421920,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr15:64421903..64421920, +
3.49e-79FFCP PHASE1:Hg19::chr8:133895195..133895206,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133895195..133895206, +
3.49e-79FFCP PHASE2:Hg19::chr7:88388628..88388669,+#_c3acdbdab95ff7e7ff9785f331e9ff61p6@ZNF804B
3.49e-79FFCP PHASE1:Hg19::chr8:11333494..11333497,-#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:11333494..11333497, -
3.49e-79FFCP PHASE2:Hg19::chr8:133900339..133900344,-#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133900339..133900344, -
3.49e-79FFCP PHASE2:Hg19::chr2:1459978..1459990,-#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr2:1459978..1459990, -
3.49e-79FFCP PHASE1:Hg19::chr8:133978809..133978829,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133978809..133978829, +
3.49e-79FFCP PHASE2:Hg19::chr8:133906083..133906088,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133906083..133906088, +
3.49e-79FFCP PHASE1:Hg19::chr8:134108463..134108470,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:134108463..134108470, +
3.49e-79FFCP PHASE2:Hg19::chr6:148533199..148533206,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr6:148533199..148533206, +
3.49e-79FFCP PHASE1:Hg19::chr2:1426850..1426859,+#_c3acdbdab95ff7e7ff9785f331e9ff61p10@TPO
3.49e-79FFCP PHASE2:Hg19::chr2:1440089..1440096,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr2:1440089..1440096, +
3.49e-79FFCP PHASE1:Hg19::chr8:133898904..133898911,+#_c3acdbdab95ff7e7ff9785f331e9ff61p@chr8:133898904..133898911, +

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