MCL coexpression mm9:1965

Phase1 CAGE Peaks

	Short description
Mm9::chr11:3831548..3831573,-	p@chr11:3831548..3831573 -
Mm9::chr11:3831591..3831602,-	p@chr11:3831591..3831602 -
Mm9::chr2:68224732..68224750,-	p7@Stk39
Mm9::chr3:129457796..129457830,-	p@chr3:129457796..129457830 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0015889	cobalamin transport	0.0224360675481166
GO:0015087	cobalt ion transmembrane transporter activity	0.0224360675481166
GO:0051180	vitamin transport	0.0224360675481166
GO:0006824	cobalt ion transport	0.0224360675481166
GO:0031419	cobalamin binding	0.0224360675481166
GO:0021940	positive regulation of granule cell precursor proliferation	0.0224360675481166
GO:0021936	regulation of granule cell precursor proliferation	0.0224360675481166
GO:0021534	cell proliferation in hindbrain	0.0224360675481166
GO:0021924	cell proliferation in the external granule layer	0.0224360675481166
GO:0021930	granule cell precursor proliferation	0.0224360675481166
GO:0050897	cobalt ion binding	0.0224360675481166
GO:0000186	activation of MAPKK activity	0.0224360675481166
GO:0007173	epidermal growth factor receptor signaling pathway	0.0225917250643957
GO:0006468	protein amino acid phosphorylation	0.032808170115595
GO:0016310	phosphorylation	0.0366874167746968
GO:0046915	transition metal ion transmembrane transporter activity	0.0366874167746968
GO:0032147	activation of protein kinase activity	0.0395774152083312
GO:0015082	di-, tri-valent inorganic cation transmembrane transporter activity	0.0395774152083312
GO:0006793	phosphorus metabolic process	0.0395774152083312
GO:0006796	phosphate metabolic process	0.0395774152083312
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	0.0395774152083312
GO:0030902	hindbrain development	0.0429072138016966
GO:0016324	apical plasma membrane	0.0429072138016966
GO:0033238	regulation of amine metabolic process	0.0429072138016966
GO:0001932	regulation of protein amino acid phosphorylation	0.0429072138016966
GO:0006521	regulation of amino acid metabolic process	0.0429072138016966
GO:0018212	peptidyl-tyrosine modification	0.0429072138016966
GO:0042325	regulation of phosphorylation	0.0429072138016966
GO:0018108	peptidyl-tyrosine phosphorylation	0.0429072138016966
GO:0051174	regulation of phosphorus metabolic process	0.0429072138016966
GO:0019220	regulation of phosphate metabolic process	0.0429072138016966
GO:0048754	branching morphogenesis of a tube	0.0429072138016966
GO:0000041	transition metal ion transport	0.0429072138016966
GO:0001763	morphogenesis of a branching structure	0.0452229396790126
GO:0016323	basolateral plasma membrane	0.0487933223552719

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
adult organism	2.15e-07	51
renal system	3.73e-07	19
urinary system structure	3.81e-07	18
kidney	9.68e-07	14
kidney mesenchyme	9.68e-07	14
upper urinary tract	9.68e-07	14
kidney rudiment	9.68e-07	14
kidney field	9.68e-07	14

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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