MCL coexpression mm9:1216

Phase1 CAGE Peaks

	Short description
Mm9::chr10:106560641..106560729,-	p1@Acss3
Mm9::chr10:106560828..106560850,-	p2@Acss3
Mm9::chr7:126904432..126904448,+	p2@Acsm3
Mm9::chr7:126904457..126904477,+	p1@Acsm3
Mm9::chr7:126904495..126904502,+	p3@Acsm3
Mm9::chr9:108177418..108177465,-	p@chr9:108177418..108177465 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0047760	butyrate-CoA ligase activity	0.0111579831625851
GO:0016878	acid-thiol ligase activity	0.0111579831625851
GO:0015645	fatty-acid ligase activity	0.0111579831625851
GO:0016877	ligase activity, forming carbon-sulfur bonds	0.0148057853503534
GO:0031980	mitochondrial lumen	0.0208854556633004
GO:0005759	mitochondrial matrix	0.0208854556633004
GO:0006633	fatty acid biosynthetic process	0.0208854556633004
GO:0046394	carboxylic acid biosynthetic process	0.0208854556633004
GO:0016053	organic acid biosynthetic process	0.0208854556633004
GO:0006631	fatty acid metabolic process	0.0411987070618528
GO:0032787	monocarboxylic acid metabolic process	0.049859798887356

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
exocrine gland	1.96e-14	25
exocrine system	1.96e-14	25
digestive tract diverticulum	5.38e-13	23
sac	5.38e-13	23
liver	1.34e-12	22
epithelial sac	1.34e-12	22
digestive gland	1.34e-12	22
epithelium of foregut-midgut junction	1.34e-12	22
anatomical boundary	1.34e-12	22
hepatobiliary system	1.34e-12	22
foregut-midgut junction	1.34e-12	22
hepatic diverticulum	1.34e-12	22
liver primordium	1.34e-12	22
septum transversum	1.34e-12	22
liver bud	1.34e-12	22
abdomen element	1.00e-11	49
abdominal segment element	1.00e-11	49
abdominal segment of trunk	1.00e-11	49
abdomen	1.00e-11	49
trunk mesenchyme	1.20e-10	45
subdivision of trunk	2.60e-10	66
mesenchyme	1.03e-09	61
entire embryonic mesenchyme	1.03e-09	61
trunk region element	3.91e-09	79
immaterial anatomical entity	3.27e-07	79
trunk	7.45e-07	90

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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