MCL coexpression mm9:3123
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr17:87153028..87153049,+ | p2@Epas1 |
| Mm9::chr17:87153240..87153254,+ | p1@Epas1 |
| Mm9::chr2:60800858..60800878,- | p6@Rbms1 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0043618 | regulation of transcription from RNA polymerase II promoter in response to stress | 0.0130597933285795 |
| GO:0043619 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress | 0.0130597933285795 |
| GO:0043620 | regulation of transcription in response to stress | 0.0130597933285795 |
| GO:0048875 | chemical homeostasis within a tissue | 0.0130597933285795 |
| GO:0043129 | surfactant homeostasis | 0.0130597933285795 |
| GO:0042415 | norepinephrine metabolic process | 0.0136035786831511 |
| GO:0002027 | regulation of heart rate | 0.0224422150894195 |
| GO:0001892 | embryonic placenta development | 0.0224422150894195 |
| GO:0001974 | blood vessel remodeling | 0.0244757078470398 |
| GO:0033554 | cellular response to stress | 0.0244757078470398 |
| GO:0051716 | cellular response to stimulus | 0.0244757078470398 |
| GO:0003697 | single-stranded DNA binding | 0.0244757078470398 |
| GO:0001666 | response to hypoxia | 0.0244757078470398 |
| GO:0003690 | double-stranded DNA binding | 0.0244757078470398 |
| GO:0001894 | tissue homeostasis | 0.0248996451830171 |
| GO:0048871 | multicellular organismal homeostasis | 0.0248996451830171 |
| GO:0001890 | placenta development | 0.0248996451830171 |
| GO:0018958 | phenol metabolic process | 0.0248996451830171 |
| GO:0006584 | catecholamine metabolic process | 0.0248996451830171 |
| GO:0008016 | regulation of heart contraction | 0.027430425466154 |
| GO:0042133 | neurotransmitter metabolic process | 0.027430425466154 |
| GO:0030218 | erythrocyte differentiation | 0.027430425466154 |
| GO:0003015 | heart process | 0.0293515286077098 |
| GO:0060047 | heart contraction | 0.0293515286077098 |
| GO:0006979 | response to oxidative stress | 0.0293515286077098 |
| GO:0043566 | structure-specific DNA binding | 0.0301016548785821 |
| GO:0046982 | protein heterodimerization activity | 0.0362215470398131 |
| GO:0030324 | lung development | 0.0363956629082699 |
| GO:0030323 | respiratory tube development | 0.0363956629082699 |
| GO:0007005 | mitochondrion organization and biogenesis | 0.0363956629082699 |
| GO:0006576 | biogenic amine metabolic process | 0.0376785679627757 |
| GO:0048469 | cell maturation | 0.0376785679627757 |
| GO:0042445 | hormone metabolic process | 0.0386746014954127 |
| GO:0006575 | amino acid derivative metabolic process | 0.0386746014954127 |
| GO:0001505 | regulation of neurotransmitter levels | 0.0386746014954127 |
| GO:0021700 | developmental maturation | 0.0386746014954127 |
| GO:0030099 | myeloid cell differentiation | 0.0386746014954127 |
| GO:0003677 | DNA binding | 0.0386746014954127 |
| GO:0008015 | blood circulation | 0.0386746014954127 |
| GO:0003013 | circulatory system process | 0.0386746014954127 |
| GO:0007601 | visual perception | 0.0427717939759727 |
| GO:0050953 | sensory perception of light stimulus | 0.0427717939759727 |
| GO:0006725 | aromatic compound metabolic process | 0.0427717939759727 |
| GO:0001701 | in utero embryonic development | 0.0437547144648331 |
| GO:0048771 | tissue remodeling | 0.0437547144648331 |
| GO:0006260 | DNA replication | 0.046721929108951 |
| GO:0001525 | angiogenesis | 0.046721929108951 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| tube | 4.01e-13 | 114 |
| anatomical conduit | 2.70e-12 | 122 |
| trunk region element | 9.96e-11 | 79 |
| subdivision of trunk | 1.00e-10 | 66 |
| trunk | 1.34e-09 | 90 |
| multi-cellular organism | 3.80e-08 | 333 |
| epithelial tube | 6.39e-08 | 47 |
| tissue | 1.04e-07 | 349 |
| abdomen element | 1.27e-07 | 49 |
| abdominal segment element | 1.27e-07 | 49 |
| abdominal segment of trunk | 1.27e-07 | 49 |
| abdomen | 1.27e-07 | 49 |
| organ | 3.67e-07 | 266 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.526413 |
| MA0004.1 | 0.801718 |
| MA0006.1 | 0.60285 |
| MA0007.1 | 0.784593 |
| MA0009.1 | 1.27673 |
| MA0014.1 | 1.33691 |
| MA0017.1 | 0.635031 |
| MA0019.1 | 1.08369 |
| MA0024.1 | 1.23079 |
| MA0025.1 | 1.51835 |
| MA0027.1 | 2.9431 |
| MA0028.1 | 0.61552 |
| MA0029.1 | 1.20789 |
| MA0030.1 | 1.21482 |
| MA0031.1 | 1.17722 |
| MA0038.1 | 0.963265 |
| MA0040.1 | 1.28983 |
| MA0041.1 | 0.714279 |
| MA0042.1 | 0.69885 |
| MA0043.1 | 1.3775 |
| MA0046.1 | 1.31428 |
| MA0048.1 | 0.353763 |
| MA0050.1 | 0.845669 |
| MA0051.1 | 0.973068 |
| MA0052.1 | 1.29825 |
| MA0055.1 | 1.06076 |
| MA0056.1 | 0 |
| MA0057.1 | 0.337566 |
| MA0058.1 | 0.690848 |
| MA0059.1 | 0.705317 |
| MA0060.1 | 0.502699 |
| MA0061.1 | 0.5406 |
| MA0063.1 | 0 |
| MA0066.1 | 0.951196 |
| MA0067.1 | 1.63197 |
| MA0068.1 | 0.343188 |
| MA0069.1 | 1.29861 |
| MA0070.1 | 1.28847 |
| MA0071.1 | 0.844726 |
| MA0072.1 | 1.2796 |
| MA0073.1 | 0.439282 |
| MA0074.1 | 0.911576 |
| MA0076.1 | 0.657929 |
| MA0077.1 | 1.2569 |
| MA0078.1 | 1.0091 |
| MA0081.1 | 0.732313 |
| MA0083.1 | 1.37668 |
| MA0084.1 | 1.96428 |
| MA0087.1 | 1.33189 |
| MA0088.1 | 0.27999 |
| MA0089.1 | 0 |
| MA0090.1 | 0.762482 |
| MA0091.1 | 0.816659 |
| MA0092.1 | 0.762845 |
| MA0093.1 | 0.62555 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.89873 |
| MA0101.1 | 0.71579 |
| MA0103.1 | 0.647985 |
| MA0105.1 | 0.405648 |
| MA0106.1 | 1.01755 |
| MA0107.1 | 0.640607 |
| MA0108.2 | 1.10817 |
| MA0109.1 | 0 |
| MA0111.1 | 0.778753 |
| MA0113.1 | 0.986839 |
| MA0114.1 | 0.537669 |
| MA0115.1 | 1.38041 |
| MA0116.1 | 0.602598 |
| MA0117.1 | 1.34691 |
| MA0119.1 | 0.716476 |
| MA0122.1 | 1.36752 |
| MA0124.1 | 1.57762 |
| MA0125.1 | 1.5017 |
| MA0130.1 | 0 |
| MA0131.1 | 1.07881 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.4152 |
| MA0136.1 | 0.933582 |
| MA0139.1 | 1.16863 |
| MA0140.1 | 0.898603 |
| MA0141.1 | 0.671467 |
| MA0142.1 | 1.16183 |
| MA0143.1 | 1.00467 |
| MA0144.1 | 1.33779 |
| MA0145.1 | 0.292366 |
| MA0146.1 | 0.46063 |
| MA0147.1 | 0.556853 |
| MA0148.1 | 0.820161 |
| MA0149.1 | 0.722227 |
| MA0062.2 | 0.412742 |
| MA0035.2 | 0.903829 |
| MA0039.2 | 0.71803 |
| MA0138.2 | 1.07027 |
| MA0002.2 | 0.466067 |
| MA0137.2 | 0.668025 |
| MA0104.2 | 0.48458 |
| MA0047.2 | 0.962424 |
| MA0112.2 | 0.29236 |
| MA0065.2 | 0.292912 |
| MA0150.1 | 0.784464 |
| MA0151.1 | 0 |
| MA0152.1 | 0.962542 |
| MA0153.1 | 1.43238 |
| MA0154.1 | 0.35067 |
| MA0155.1 | 1.52001 |
| MA0156.1 | 0.656895 |
| MA0157.1 | 1.12772 |
| MA0158.1 | 0 |
| MA0159.1 | 0.569393 |
| MA0160.1 | 0.823568 |
| MA0161.1 | 0 |
| MA0162.1 | 1.53682 |
| MA0163.1 | 0.157796 |
| MA0164.1 | 0.933981 |
| MA0080.2 | 0.64167 |
| MA0018.2 | 0.944669 |
| MA0099.2 | 1.06348 |
| MA0079.2 | 1.81944 |
| MA0102.2 | 2.01714 |
| MA0258.1 | 0.520639 |
| MA0259.1 | 0.543506 |
| MA0442.1 | 0 |
