UBERON:0002062
From FANTOM5_SSTAR
| Name: | endocardial cushion | ||
|---|---|---|---|
| Definition: | "The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves[GO]. Swellings of tissue present between the endocardial and myocardial cell layers that will give rise to the interstitial cells of the cardiac valves[ZFA]." [GO:0003197, Wikipedia:Endocardial_cushion, ZFIN:curator] | ||
| Xrefs: |
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| Synonyms: |
"atrioventricular cushion" EXACT [Wikipedia:Endocardial_cushion] "cardiac cushion" EXACT [PMID:15797462] "endocardial cushion tissue" EXACT [EHDAA2:0000434] "endocardial cushions" RELATED PLURAL [] | ||
| Comments: | GO graph seems to suggest this is an endothelium. WP: The endocardial cushions are thought to arise from a subset of endothelial cells that undergo epithelial to mesenchymal transformation, a process whereby these cells break cell-to-cell contacts and migrate into the cardiac jelly (towards to interior of the heart tube). Latest (2010-06-01) new def suggested for GO, added above. Note that EHDAA2 has a more detailed model which we may later adopt | ||
| Alt_id: | UBERON:FMA_70302-MA_0000078-ZFA_0001317 | ||
| Subset: |
uberon_slim vertebrate_core |
200px-Gray465.png]
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | UBERON:0005291(embryonic tissue),UBERON:0009751(cardiac mesenchyme),UBERON:0010313(neural crest-derived structure) |
|---|
Children
| develops from: | UBERON:0000946 (cardial valve),UBERON:0002133 (atrioventricular valve) |
|---|
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0002062 (endocardial cushion), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
| P-value | FFCP | Short description |
|---|---|---|
| 5.41e-147 | FFCP PHASE1:Hg19::chr7:25815812..25815822,-#_762ae4977c5b9bd324fb358280f418bf | p@chr7:25815812..25815822, - |
| 5.41e-147 | FFCP PHASE2:Hg19::chr7:25815812..25815822,-#_762ae4977c5b9bd324fb358280f418bf | p@chr7:25815812..25815822, - |
| 8.98e-131 | FFCP PHASE1:Hg19::chr12:3373147..3373149,-#_635dfec0fe0be947f436d2464039a74c | p@chr12:3373147..3373149, - |
| 8.98e-131 | FFCP PHASE2:Hg19::chr12:3373147..3373149,-#_635dfec0fe0be947f436d2464039a74c | p@chr12:3373147..3373149, - |
| 7.78e-118 | FFCP PHASE2:Hg19::chr1:20355975..20355980,-#_9d4ffbe77040424cb79c5ff4438cf931 | p@chr1:20355975..20355980, - |
| 7.78e-118 | FFCP PHASE1:Hg19::chr1:20355975..20355980,-#_9d4ffbe77040424cb79c5ff4438cf931 | p@chr1:20355975..20355980, - |
| 5.69e-99 | FFCP PHASE2:Hg19::chr1:237331032..237331036,+#_835fa8341d0c262fdfd6e0626569968b | p@chr1:237331032..237331036, + |
| 5.69e-99 | FFCP PHASE1:Hg19::chr1:237331032..237331036,+#_835fa8341d0c262fdfd6e0626569968b | p@chr1:237331032..237331036, + |
| 1.52e-87 | FFCP PHASE1:Hg19::chr2:18116344..18116353,+#_614cf3e9e3ccaa6d6992f7bbe160d5e7 | p@chr2:18116344..18116353, + |
| 1.52e-87 | FFCP PHASE2:Hg19::chr6:6739548..6739577,-#_614cf3e9e3ccaa6d6992f7bbe160d5e7 | p@chr6:6739548..6739577, - |
| 1.52e-87 | FFCP PHASE2:Hg19::chr2:18116344..18116353,+#_614cf3e9e3ccaa6d6992f7bbe160d5e7 | p@chr2:18116344..18116353, + |
| 1.52e-87 | FFCP PHASE2:Hg19::chr1:11907265..11907271,-#_614cf3e9e3ccaa6d6992f7bbe160d5e7 | p9@NPPA |
| 1.52e-87 | FFCP PHASE1:Hg19::chr1:11907265..11907271,-#_614cf3e9e3ccaa6d6992f7bbe160d5e7 | p9@NPPA |
| 1.52e-87 | FFCP PHASE1:Hg19::chr6:6739548..6739577,-#_614cf3e9e3ccaa6d6992f7bbe160d5e7 | p@chr6:6739548..6739577, - |
| 7.21e-85 | FFCP PHASE2:Hg19::chrX:112324334..112324339,-#_1838e9c018ff4fd86f1a9025a8b8f460 | p@chrX:112324334..112324339, - |
| 7.21e-85 | FFCP PHASE1:Hg19::chrX:112324334..112324339,-#_1838e9c018ff4fd86f1a9025a8b8f460 | p@chrX:112324334..112324339, - |
| 1.71e-84 | FFCP PHASE2:Hg19::chr2:220491902..220491915,+#_b6923c5d443c2311ba1de622c00a817d | p11@SLC4A3 |
| 1.71e-84 | FFCP PHASE1:Hg19::chr2:220491902..220491915,+#_b6923c5d443c2311ba1de622c00a817d | p11@SLC4A3 |
| 2.27e-84 | FFCP PHASE1:Hg19::chr2:179533457..179533461,-#_3712d16c33f17b194ef04727d80c5105 | p@chr2:179533457..179533461, - |
| 2.27e-84 | FFCP PHASE2:Hg19::chr2:179533457..179533461,-#_3712d16c33f17b194ef04727d80c5105 | p@chr2:179533457..179533461, - |
| 3.03e-84 | FFCP PHASE1:Hg19::chr2:179398102..179398109,-#_6d355795341c965d833156528609129c | p@chr2:179398102..179398109, - |
| 3.03e-84 | FFCP PHASE2:Hg19::chr2:179398102..179398109,-#_6d355795341c965d833156528609129c | p@chr2:179398102..179398109, - |
| 7.81e-75 | FFCP PHASE1:Hg19::chr5:123739302..123739319,-#_34e1c5ae416c19fc71c6f5e25c3eb0a7 | p@chr5:123739302..123739319, - |
| 7.81e-75 | FFCP PHASE2:Hg19::chr5:123739302..123739319,-#_34e1c5ae416c19fc71c6f5e25c3eb0a7 | p@chr5:123739302..123739319, - |
| 1.01e-74 | FFCP PHASE1:Hg19::chr18:64271475..64271484,-#_9cf5a366e88a7fe3a00e0a2f8700b81e | p6@CDH19 |
| 1.01e-74 | FFCP PHASE2:Hg19::chr18:64271475..64271484,-#_9cf5a366e88a7fe3a00e0a2f8700b81e | p6@CDH19 |
| 1.29e-74 | FFCP PHASE2:Hg19::chr7:35286774..35286778,-#_81f4a059026a07aacc21db93a7efefe7 | p@chr7:35286774..35286778, - |
| 1.29e-74 | FFCP PHASE1:Hg19::chr7:35286774..35286778,-#_81f4a059026a07aacc21db93a7efefe7 | p@chr7:35286774..35286778, - |
| 1.66e-74 | FFCP PHASE2:Hg19::chr6:129355052..129355056,+#_ad0d0bce36c8d290d1ce627c25061ca2 | p@chr6:129355052..129355056, + |
| 1.66e-74 | FFCP PHASE1:Hg19::chr6:129355052..129355056,+#_ad0d0bce36c8d290d1ce627c25061ca2 | p@chr6:129355052..129355056, + |
| 2.75e-74 | FFCP PHASE2:Hg19::chr3:16940540..16940554,+#_f4cf4c24f5f8a8d9a052066bdba31cb3 | p@chr3:16940540..16940554, + |
| 2.75e-74 | FFCP PHASE1:Hg19::chr3:16940540..16940554,+#_f4cf4c24f5f8a8d9a052066bdba31cb3 | p@chr3:16940540..16940554, + |
| 3.54e-74 | FFCP PHASE1:Hg19::chr19:55661803..55661807,-#_2d4de84d93e740177f9bae24c7ae3caf | p@chr19:55661803..55661807, - |
| 3.54e-74 | FFCP PHASE2:Hg19::chr3:131523446..131523459,-#_2d4de84d93e740177f9bae24c7ae3caf | p@chr3:131523446..131523459, - |
| 3.54e-74 | FFCP PHASE2:Hg19::chr20:33565465..33565475,+#_2d4de84d93e740177f9bae24c7ae3caf | p9@MYH7B |
| 3.54e-74 | FFCP PHASE2:Hg19::chr1:201328779..201328797,-#_2d4de84d93e740177f9bae24c7ae3caf | p@chr1:201328779..201328797, - |
| 3.54e-74 | FFCP PHASE1:Hg19::chr1:201328779..201328797,-#_2d4de84d93e740177f9bae24c7ae3caf | p@chr1:201328779..201328797, - |
| 3.54e-74 | FFCP PHASE1:Hg19::chr3:131523446..131523459,-#_2d4de84d93e740177f9bae24c7ae3caf | p@chr3:131523446..131523459, - |
| 3.54e-74 | FFCP PHASE1:Hg19::chr20:33565465..33565475,+#_2d4de84d93e740177f9bae24c7ae3caf | p9@MYH7B |
| 3.54e-74 | FFCP PHASE2:Hg19::chr19:55661803..55661807,-#_2d4de84d93e740177f9bae24c7ae3caf | p@chr19:55661803..55661807, - |
| 5.84e-74 | FFCP PHASE2:Hg19::chr6:36812121..36812130,-#_4585aca20afb02706bb3f0ed71ac21d6 | p@chr6:36812121..36812130, - |
| 5.84e-74 | FFCP PHASE1:Hg19::chr6:36812121..36812130,-#_4585aca20afb02706bb3f0ed71ac21d6 | p@chr6:36812121..36812130, - |
| 7.51e-74 | FFCP PHASE2:Hg19::chr14:105939326..105939337,+#_c6336d4cc8876434a4bcc8abd2610faf | p16@CRIP2 |
| 7.51e-74 | FFCP PHASE1:Hg19::chr14:105939326..105939337,+#_c6336d4cc8876434a4bcc8abd2610faf | p16@CRIP2 |
| 9.64e-74 | FFCP PHASE2:Hg19::chr1:206838422..206838456,+#_9c84b2e6afc7cd2e0ab422820dbb961b | p@chr1:206838422..206838456, + |
| 9.64e-74 | FFCP PHASE1:Hg19::chr1:206838422..206838456,+#_9c84b2e6afc7cd2e0ab422820dbb961b | p@chr1:206838422..206838456, + |
| 1.24e-73 | FFCP PHASE2:Hg19::chr1:231983543..231983554,-#_f3429bb285901c3571949a3976ea4396 | p@chr1:231983543..231983554, - |
| 1.24e-73 | FFCP PHASE1:Hg19::chr1:231983543..231983554,-#_f3429bb285901c3571949a3976ea4396 | p@chr1:231983543..231983554, - |
| 1.54e-66 | FFCP PHASE2:Hg19::chr1:201328328..201328343,-#_32adff27e8827c4cf61244dfd8d4515b | p@chr1:201328328..201328343, - |
| 1.54e-66 | FFCP PHASE1:Hg19::chr1:201328328..201328343,-#_32adff27e8827c4cf61244dfd8d4515b | p@chr1:201328328..201328343, - |
| 1.71e-66 | FFCP PHASE1:Hg19::chr11:47367243..47367257,-#_d0c121113f34d1b688fcb2a4a7fdbc5a | p@chr11:47367243..47367257, - |
| 1.71e-66 | FFCP PHASE2:Hg19::chr11:47367243..47367257,-#_d0c121113f34d1b688fcb2a4a7fdbc5a | p@chr11:47367243..47367257, - |
| 1.71e-66 | FFCP PHASE2:Hg19::chr1:237214095..237214115,+#_d0c121113f34d1b688fcb2a4a7fdbc5a | p@chr1:237214095..237214115, + |
| 1.71e-66 | FFCP PHASE1:Hg19::chr1:237214095..237214115,+#_d0c121113f34d1b688fcb2a4a7fdbc5a | p@chr1:237214095..237214115, + |
| 2.39e-66 | FFCP PHASE1:Hg19::chr5:99390735..99390743,-#_320cfe93e3aa96f2b04e0462a6d0a775 | p@chr5:99390735..99390743, - |
| 2.39e-66 | FFCP PHASE1:Hg19::chr10:92678409..92678410,-#_320cfe93e3aa96f2b04e0462a6d0a775 | p@chr10:92678409..92678410, - |
| 2.39e-66 | FFCP PHASE2:Hg19::chr5:99390735..99390743,-#_320cfe93e3aa96f2b04e0462a6d0a775 | p@chr5:99390735..99390743, - |
| 2.39e-66 | FFCP PHASE2:Hg19::chr15:86272097..86272099,+#_320cfe93e3aa96f2b04e0462a6d0a775 | p@chr15:86272097..86272099, + |
| 2.39e-66 | FFCP PHASE1:Hg19::chr15:86272097..86272099,+#_320cfe93e3aa96f2b04e0462a6d0a775 | p@chr15:86272097..86272099, + |
| 2.39e-66 | FFCP PHASE2:Hg19::chr10:92678409..92678410,-#_320cfe93e3aa96f2b04e0462a6d0a775 | p@chr10:92678409..92678410, - |
| 2.4e-66 | FFCP PHASE2:Hg19::chr12:4735761..4735787,-#_eed72d0370f737c0be448fbbd6c789ba | p@chr12:4735761..4735787, - |
| 2.4e-66 | FFCP PHASE1:Hg19::chr2:159976509..159976519,+#_eed72d0370f737c0be448fbbd6c789ba | p@chr2:159976509..159976519, + |
| 2.4e-66 | FFCP PHASE2:Hg19::chr1:237996521..237996532,+#_eed72d0370f737c0be448fbbd6c789ba | p@chr1:237996521..237996532, + |
| 2.4e-66 | FFCP PHASE1:Hg19::chr12:114886577..114886589,-#_eed72d0370f737c0be448fbbd6c789ba | p@chr12:114886577..114886589, - |
| 2.4e-66 | FFCP PHASE1:Hg19::chr1:237996521..237996532,+#_eed72d0370f737c0be448fbbd6c789ba | p@chr1:237996521..237996532, + |
| 2.4e-66 | FFCP PHASE2:Hg19::chr12:114886577..114886589,-#_eed72d0370f737c0be448fbbd6c789ba | p@chr12:114886577..114886589, - |
| 2.4e-66 | FFCP PHASE2:Hg19::chr2:159976509..159976519,+#_eed72d0370f737c0be448fbbd6c789ba | p@chr2:159976509..159976519, + |
| 2.4e-66 | FFCP PHASE1:Hg19::chr12:4735761..4735787,-#_eed72d0370f737c0be448fbbd6c789ba | p@chr12:4735761..4735787, - |
| 2.41e-66 | FFCP PHASE1:Hg19::chr2:40480968..40480972,-#_adc1ad9f0cbb8957437efc6d203881c8 | p@chr2:40480968..40480972, - |
| 2.41e-66 | FFCP PHASE1:Hg19::chr1:237207955..237207959,+#_adc1ad9f0cbb8957437efc6d203881c8 | p@chr1:237207955..237207959, + |
| 2.41e-66 | FFCP PHASE2:Hg19::chr2:40480968..40480972,-#_adc1ad9f0cbb8957437efc6d203881c8 | p@chr2:40480968..40480972, - |
| 2.41e-66 | FFCP PHASE2:Hg19::chr1:237207955..237207959,+#_adc1ad9f0cbb8957437efc6d203881c8 | p@chr1:237207955..237207959, + |
| 3.01e-66 | FFCP PHASE2:Hg19::chr4:62999501..62999517,+#_bad1e60ac900d5e49fab32830b452cf9 | p@chr4:62999501..62999517, + |
| 3.01e-66 | FFCP PHASE1:Hg19::chr4:62999501..62999517,+#_bad1e60ac900d5e49fab32830b452cf9 | p@chr4:62999501..62999517, + |
| 3.35e-66 | FFCP PHASE1:Hg19::chr1:11905830..11905839,-#_00f976b9b63b66ea4f46f7ebebd1e975 | p@chr1:11905830..11905839, - |
| 3.35e-66 | FFCP PHASE1:Hg19::chr5:65736120..65736128,-#_00f976b9b63b66ea4f46f7ebebd1e975 | p@chr5:65736120..65736128, - |
| 3.35e-66 | FFCP PHASE1:Hg19::chr7:35253487..35253489,-#_00f976b9b63b66ea4f46f7ebebd1e975 | p@chr7:35253487..35253489, - |
| 3.35e-66 | FFCP PHASE2:Hg19::chr7:44179972..44179982,-#_00f976b9b63b66ea4f46f7ebebd1e975 | p2@MYL7 |
| 3.35e-66 | FFCP PHASE1:Hg19::chr9:38650254..38650266,+#_00f976b9b63b66ea4f46f7ebebd1e975 | p@chr9:38650254..38650266, + |
| 3.35e-66 | FFCP PHASE1:Hg19::chr7:44178491..44178498,-#_00f976b9b63b66ea4f46f7ebebd1e975 | p@chr7:44178491..44178498, - |
| 3.35e-66 | FFCP PHASE2:Hg19::chr5:65736120..65736128,-#_00f976b9b63b66ea4f46f7ebebd1e975 | p@chr5:65736120..65736128, - |
| 3.35e-66 | FFCP PHASE2:Hg19::chr7:35253487..35253489,-#_00f976b9b63b66ea4f46f7ebebd1e975 | p@chr7:35253487..35253489, - |
| 3.35e-66 | FFCP PHASE2:Hg19::chr1:11905830..11905839,-#_00f976b9b63b66ea4f46f7ebebd1e975 | p@chr1:11905830..11905839, - |
| 3.35e-66 | FFCP PHASE2:Hg19::chr9:38650254..38650266,+#_00f976b9b63b66ea4f46f7ebebd1e975 | p@chr9:38650254..38650266, + |
| 3.35e-66 | FFCP PHASE1:Hg19::chr7:44179972..44179982,-#_00f976b9b63b66ea4f46f7ebebd1e975 | p2@MYL7 |
| 3.35e-66 | FFCP PHASE2:Hg19::chr7:44178491..44178498,-#_00f976b9b63b66ea4f46f7ebebd1e975 | p@chr7:44178491..44178498, - |
| 4.68e-66 | FFCP PHASE1:Hg19::chr10:112524543..112524547,+#_2b43ebfc718e686002f1d658707ef529 | p@chr10:112524543..112524547, + |
| 4.68e-66 | FFCP PHASE1:Hg19::chr7:44180643..44180652,-#_2b43ebfc718e686002f1d658707ef529 | p3@MYL7 |
| 4.68e-66 | FFCP PHASE2:Hg19::chr10:112524543..112524547,+#_2b43ebfc718e686002f1d658707ef529 | p@chr10:112524543..112524547, + |
| 4.68e-66 | FFCP PHASE2:Hg19::chr7:44180643..44180652,-#_2b43ebfc718e686002f1d658707ef529 | p3@MYL7 |
| 5.88e-66 | FFCP PHASE2:Hg19::chr6:36812225..36812238,-#_6383d00ed1700d11123d76136b0502d9 | p@chr6:36812225..36812238, - |
| 5.88e-66 | FFCP PHASE1:Hg19::chr6:36812225..36812238,-#_6383d00ed1700d11123d76136b0502d9 | p@chr6:36812225..36812238, - |
| 6.53e-66 | FFCP PHASE2:Hg19::chr2:168104544..168104551,+#_6706794ff9487bb2342359a937f82663 | p52@XIRP2 |
| 6.53e-66 | FFCP PHASE1:Hg19::chr4:62999459..62999462,+#_6706794ff9487bb2342359a937f82663 | p@chr4:62999459..62999462, + |
| 6.53e-66 | FFCP PHASE2:Hg19::chr4:62999459..62999462,+#_6706794ff9487bb2342359a937f82663 | p@chr4:62999459..62999462, + |
| 6.53e-66 | FFCP PHASE1:Hg19::chr2:168104544..168104551,+#_6706794ff9487bb2342359a937f82663 | p52@XIRP2 |
| 1.15e-65 | FFCP PHASE2:Hg19::chr7:123302841..123302854,+#_11c3f3e32e63b6f00697e6018ad79c94 | p@chr7:123302841..123302854, + |
| 1.15e-65 | FFCP PHASE2:Hg19::chr10:127569398..127569410,-#_11c3f3e32e63b6f00697e6018ad79c94 | p5@DHX32 |
| 1.15e-65 | FFCP PHASE2:Hg19::chrX:121555838..121555874,+#_11c3f3e32e63b6f00697e6018ad79c94 | p@chrX:121555838..121555874, + |
| 1.15e-65 | FFCP PHASE1:Hg19::chr7:123302841..123302854,+#_11c3f3e32e63b6f00697e6018ad79c94 | p@chr7:123302841..123302854, + |
Property "Property value" (as page type) with input value "UBPROP:0000001 "Swellings of tissue present between the endocardial and myocardial cell layers that will give rise to the interstitial cells of the cardiac valves.[TAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process., Property "Property value" (as page type) with input value "UBPROP:0000002 "relationship loss: develops_from endocardial ring (TAO:0005072)[TAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.
