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MCL coexpression mm9:910

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Phase1 CAGE Peaks

 Short description
Mm9::chr11:6375884..6375920,-p2@Purb
Mm9::chr11:74986055..74986071,+p1@ENSMUST00000134252
Mm9::chr14:70480962..70480969,+p@chr14:70480962..70480969
+
Mm9::chr15:101105031..101105041,+p@chr15:101105031..101105041
+
Mm9::chr1:36996339..36996348,-p5@Tmem131
Mm9::chr1:52289825..52289842,-p6@Gls
Mm9::chr4:86503216..86503253,-p2@Gm13654
p2@LOC639593
p2@Rps6
Mm9::chr5:150438847..150438866,-p2@Hsph1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0006543glutamine catabolic process0.0188916839156807
GO:0004359glutaminase activity0.0188916839156807
GO:0002087neurological control of breathing0.0188916839156807
GO:0003016respiratory system process0.0188916839156807
GO:0005662DNA replication factor A complex0.0188916839156807
GO:0046332SMAD binding0.0188916839156807
GO:0030894replisome0.0188916839156807
GO:0009065glutamine family amino acid catabolic process0.0188916839156807
GO:0043601nuclear replisome0.0188916839156807
GO:0043596nuclear replication fork0.0188916839156807
GO:0006541glutamine metabolic process0.0257543293727709
GO:0003697single-stranded DNA binding0.0304989438990855
GO:0003690double-stranded DNA binding0.0304989438990855
GO:0005657replication fork0.0323609045376041
GO:0009064glutamine family amino acid metabolic process0.0353831001632472
GO:0003729mRNA binding0.0353831001632472
GO:0009063amino acid catabolic process0.047627045670694
GO:0043566structure-specific DNA binding0.047627045670694
GO:0016811hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides0.047627045670694



Relative expression of the co-expression cluster over median <br>Analyst:



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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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