MCL coexpression mm9:910
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr11:6375884..6375920,- | p2@Purb |
| Mm9::chr11:74986055..74986071,+ | p1@ENSMUST00000134252 |
| Mm9::chr14:70480962..70480969,+ | p@chr14:70480962..70480969 + |
| Mm9::chr15:101105031..101105041,+ | p@chr15:101105031..101105041 + |
| Mm9::chr1:36996339..36996348,- | p5@Tmem131 |
| Mm9::chr1:52289825..52289842,- | p6@Gls |
| Mm9::chr4:86503216..86503253,- | p2@Gm13654 p2@LOC639593 p2@Rps6 |
| Mm9::chr5:150438847..150438866,- | p2@Hsph1 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0006543 | glutamine catabolic process | 0.0188916839156807 |
| GO:0004359 | glutaminase activity | 0.0188916839156807 |
| GO:0002087 | neurological control of breathing | 0.0188916839156807 |
| GO:0003016 | respiratory system process | 0.0188916839156807 |
| GO:0005662 | DNA replication factor A complex | 0.0188916839156807 |
| GO:0046332 | SMAD binding | 0.0188916839156807 |
| GO:0030894 | replisome | 0.0188916839156807 |
| GO:0009065 | glutamine family amino acid catabolic process | 0.0188916839156807 |
| GO:0043601 | nuclear replisome | 0.0188916839156807 |
| GO:0043596 | nuclear replication fork | 0.0188916839156807 |
| GO:0006541 | glutamine metabolic process | 0.0257543293727709 |
| GO:0003697 | single-stranded DNA binding | 0.0304989438990855 |
| GO:0003690 | double-stranded DNA binding | 0.0304989438990855 |
| GO:0005657 | replication fork | 0.0323609045376041 |
| GO:0009064 | glutamine family amino acid metabolic process | 0.0353831001632472 |
| GO:0003729 | mRNA binding | 0.0353831001632472 |
| GO:0009063 | amino acid catabolic process | 0.047627045670694 |
| GO:0043566 | structure-specific DNA binding | 0.047627045670694 |
| GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | 0.047627045670694 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| regional part of nervous system | 1.80e-15 | 54 |
| neural tube | 2.82e-14 | 52 |
| neural rod | 2.82e-14 | 52 |
| future spinal cord | 2.82e-14 | 52 |
| neural keel | 2.82e-14 | 52 |
| central nervous system | 3.27e-14 | 73 |
| nervous system | 4.08e-14 | 75 |
| brain | 2.21e-12 | 47 |
| future brain | 2.21e-12 | 47 |
| ectoderm-derived structure | 5.15e-12 | 95 |
| ectoderm | 5.15e-12 | 95 |
| presumptive ectoderm | 5.15e-12 | 95 |
| regional part of brain | 8.45e-12 | 46 |
| ecto-epithelium | 1.43e-11 | 73 |
| neurectoderm | 2.80e-11 | 64 |
| neural plate | 2.80e-11 | 64 |
| presumptive neural plate | 2.80e-11 | 64 |
| anterior neural tube | 5.86e-11 | 40 |
| regional part of forebrain | 1.97e-10 | 39 |
| forebrain | 1.97e-10 | 39 |
| future forebrain | 1.97e-10 | 39 |
| gray matter | 4.32e-09 | 34 |
| organ part | 8.17e-09 | 99 |
| pre-chordal neural plate | 9.07e-09 | 49 |
| occipital lobe | 2.71e-08 | 10 |
| visual cortex | 2.71e-08 | 10 |
| neocortex | 2.71e-08 | 10 |
| brain grey matter | 2.74e-07 | 29 |
| regional part of telencephalon | 2.74e-07 | 29 |
| telencephalon | 2.74e-07 | 29 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 3.09165 |
| MA0004.1 | 0.434673 |
| MA0006.1 | 1.37063 |
| MA0007.1 | 1.07722 |
| MA0009.1 | 0.870101 |
| MA0014.1 | 1.54572 |
| MA0017.1 | 0.296816 |
| MA0019.1 | 0.688051 |
| MA0024.1 | 0.826339 |
| MA0025.1 | 1.10341 |
| MA0027.1 | 2.51754 |
| MA0028.1 | 0.769859 |
| MA0029.1 | 0.804619 |
| MA0030.1 | 0.811181 |
| MA0031.1 | 0.775627 |
| MA0038.1 | 0.577528 |
| MA0040.1 | 0.882616 |
| MA0041.1 | 0.360875 |
| MA0042.1 | 0.348174 |
| MA0043.1 | 0.966833 |
| MA0046.1 | 0.906029 |
| MA0048.1 | 0.685543 |
| MA0050.1 | 0.472794 |
| MA0051.1 | 0.586414 |
| MA0052.1 | 0.890676 |
| MA0055.1 | 0.117901 |
| MA0056.1 | 0 |
| MA0057.1 | 0.31126 |
| MA0058.1 | 0.341628 |
| MA0059.1 | 0.353484 |
| MA0060.1 | 0.197678 |
| MA0061.1 | 0.224905 |
| MA0063.1 | 0 |
| MA0066.1 | 0.566617 |
| MA0067.1 | 1.21448 |
| MA0068.1 | 0.0965831 |
| MA0069.1 | 0.891016 |
| MA0070.1 | 0.881319 |
| MA0071.1 | 0.471969 |
| MA0072.1 | 0.872842 |
| MA0073.1 | 0.138438 |
| MA0074.1 | 0.531046 |
| MA0076.1 | 1.52758 |
| MA0077.1 | 0.851175 |
| MA0078.1 | 0.61926 |
| MA0081.1 | 0.980744 |
| MA0083.1 | 0.96604 |
| MA0084.1 | 1.54225 |
| MA0087.1 | 0.922929 |
| MA0088.1 | 0.229377 |
| MA0089.1 | 0 |
| MA0090.1 | 0.401197 |
| MA0091.1 | 1.13691 |
| MA0092.1 | 0.401504 |
| MA0093.1 | 0.787675 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.519598 |
| MA0101.1 | 0.362124 |
| MA0103.1 | 0.307078 |
| MA0105.1 | 1.33477 |
| MA0106.1 | 0.626997 |
| MA0107.1 | 0.301222 |
| MA0108.2 | 1.69252 |
| MA0109.1 | 0 |
| MA0111.1 | 0.415012 |
| MA0113.1 | 0.598933 |
| MA0114.1 | 0.633896 |
| MA0115.1 | 0.969632 |
| MA0116.1 | 0.27152 |
| MA0117.1 | 2.15835 |
| MA0119.1 | 0.362692 |
| MA0122.1 | 0.957212 |
| MA0124.1 | 1.16127 |
| MA0125.1 | 1.0872 |
| MA0130.1 | 0 |
| MA0131.1 | 0.683521 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.00325 |
| MA0136.1 | 0.550755 |
| MA0139.1 | 0.977634 |
| MA0140.1 | 0.519484 |
| MA0141.1 | 0.325895 |
| MA0142.1 | 0.761136 |
| MA0143.1 | 0.615203 |
| MA0144.1 | 0.225588 |
| MA0145.1 | 0.527241 |
| MA0146.1 | 1.31232 |
| MA0147.1 | 0.666991 |
| MA0148.1 | 0.450593 |
| MA0149.1 | 0.367458 |
| MA0062.2 | 3.38762 |
| MA0035.2 | 0.524137 |
| MA0039.2 | 1.07211 |
| MA0138.2 | 0.675599 |
| MA0002.2 | 0.172399 |
| MA0137.2 | 0.32312 |
| MA0104.2 | 0.54394 |
| MA0047.2 | 0.576767 |
| MA0112.2 | 0.527225 |
| MA0065.2 | 0.528619 |
| MA0150.1 | 0.419883 |
| MA0151.1 | 0 |
| MA0152.1 | 0.576873 |
| MA0153.1 | 1.01988 |
| MA0154.1 | 0.100744 |
| MA0155.1 | 0.0804339 |
| MA0156.1 | 0.314185 |
| MA0157.1 | 0.729116 |
| MA0158.1 | 0 |
| MA0159.1 | 0.246253 |
| MA0160.1 | 0.453546 |
| MA0161.1 | 0 |
| MA0162.1 | 4.72045 |
| MA0163.1 | 0.408151 |
| MA0164.1 | 0.551114 |
| MA0080.2 | 0.302064 |
| MA0018.2 | 1.37842 |
| MA0099.2 | 0.669311 |
| MA0079.2 | 2.0883 |
| MA0102.2 | 1.59466 |
| MA0258.1 | 0.210437 |
| MA0259.1 | 0.643936 |
| MA0442.1 | 0 |
