MCL coexpression mm9:141
From FANTOM5_SSTAR
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0043565 | sequence-specific DNA binding | 0.000722796353711021 |
GO:0003677 | DNA binding | 0.000722796353711021 |
GO:0003700 | transcription factor activity | 0.000722796353711021 |
GO:0007399 | nervous system development | 0.00258427050557105 |
GO:0003676 | nucleic acid binding | 0.00624829843874097 |
GO:0005667 | transcription factor complex | 0.00624829843874097 |
GO:0044451 | nucleoplasm part | 0.0108935557334897 |
GO:0005654 | nucleoplasm | 0.0108935557334897 |
GO:0048731 | system development | 0.0108935557334897 |
GO:0035270 | endocrine system development | 0.0108935557334897 |
GO:0007417 | central nervous system development | 0.0108935557334897 |
GO:0021546 | rhombomere development | 0.0109169893314966 |
GO:0021568 | rhombomere 2 development | 0.0109169893314966 |
GO:0021555 | midbrain-hindbrain boundary morphogenesis | 0.0109169893314966 |
GO:0021529 | spinal cord oligodendrocyte cell differentiation | 0.0109169893314966 |
GO:0006355 | regulation of transcription, DNA-dependent | 0.0109169893314966 |
GO:0031981 | nuclear lumen | 0.0109169893314966 |
GO:0006351 | transcription, DNA-dependent | 0.0109169893314966 |
GO:0032774 | RNA biosynthetic process | 0.0109169893314966 |
GO:0021915 | neural tube development | 0.0109169893314966 |
GO:0045449 | regulation of transcription | 0.0109169893314966 |
GO:0048856 | anatomical structure development | 0.0109169893314966 |
GO:0019219 | regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 0.0109169893314966 |
GO:0007548 | sex differentiation | 0.0109169893314966 |
GO:0006350 | transcription | 0.0109169893314966 |
GO:0048699 | generation of neurons | 0.0109169893314966 |
GO:0031974 | membrane-enclosed lumen | 0.0109169893314966 |
GO:0043233 | organelle lumen | 0.0109169893314966 |
GO:0021985 | neurohypophysis development | 0.0109169893314966 |
GO:0048619 | embryonic hindgut morphogenesis | 0.0109169893314966 |
GO:0010468 | regulation of gene expression | 0.010928822901222 |
GO:0048513 | organ development | 0.010928822901222 |
GO:0022008 | neurogenesis | 0.010928822901222 |
GO:0003006 | reproductive developmental process | 0.0111933700652562 |
GO:0031323 | regulation of cellular metabolic process | 0.0116929294713598 |
GO:0007275 | multicellular organismal development | 0.0116929294713598 |
GO:0030917 | midbrain-hindbrain boundary development | 0.0116929294713598 |
GO:0035112 | genitalia morphogenesis | 0.0116929294713598 |
GO:0021903 | rostrocaudal neural tube patterning | 0.0116929294713598 |
GO:0021979 | hypothalamus cell differentiation | 0.0116929294713598 |
GO:0021854 | hypothalamus development | 0.0116929294713598 |
GO:0030538 | embryonic genitalia morphogenesis | 0.0116929294713598 |
GO:0019222 | regulation of metabolic process | 0.0119391502240456 |
GO:0016070 | RNA metabolic process | 0.0133665433799887 |
GO:0016055 | Wnt receptor signaling pathway | 0.0165643234605085 |
GO:0007442 | hindgut morphogenesis | 0.0170409815340593 |
GO:0014003 | oligodendrocyte development | 0.0170409815340593 |
GO:0048665 | neuron fate specification | 0.0170409815340593 |
GO:0008283 | cell proliferation | 0.017899236553586 |
GO:0044428 | nuclear part | 0.0179165213157274 |
GO:0048613 | embryonic ectodermal gut morphogenesis | 0.0185139237974193 |
GO:0005883 | neurofilament | 0.0185139237974193 |
GO:0048611 | embryonic ectodermal gut development | 0.0185139237974193 |
GO:0021515 | cell differentiation in spinal cord | 0.0200772181590761 |
GO:0002052 | positive regulation of neuroblast proliferation | 0.0200772181590761 |
GO:0048483 | autonomic nervous system development | 0.0200772181590761 |
GO:0031018 | endocrine pancreas development | 0.0200772181590761 |
GO:0021532 | neural tube patterning | 0.0221602983013529 |
GO:0048558 | embryonic gut morphogenesis | 0.0221602983013529 |
GO:0060053 | neurofilament cytoskeleton | 0.0230034966293408 |
GO:0060052 | neurofilament cytoskeleton organization and biogenesis | 0.0230034966293408 |
GO:0048557 | embryonic digestive tract morphogenesis | 0.0230034966293408 |
GO:0010467 | gene expression | 0.0230034966293408 |
GO:0007439 | ectodermal gut development | 0.0230034966293408 |
GO:0021534 | cell proliferation in hindbrain | 0.0230034966293408 |
GO:0021761 | limbic system development | 0.0230034966293408 |
GO:0021924 | cell proliferation in the external granule layer | 0.0230034966293408 |
GO:0048567 | ectodermal gut morphogenesis | 0.0230034966293408 |
GO:0048709 | oligodendrocyte differentiation | 0.0230034966293408 |
GO:0021930 | granule cell precursor proliferation | 0.0230034966293408 |
GO:0021782 | glial cell development | 0.0230034966293408 |
GO:0007420 | brain development | 0.0234086639261353 |
GO:0048547 | gut morphogenesis | 0.0242700390021904 |
GO:0048806 | genitalia development | 0.0242700390021904 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 0.0252515601205765 |
GO:0032502 | developmental process | 0.0252515601205765 |
GO:0048598 | embryonic morphogenesis | 0.0252515601205765 |
GO:0032991 | macromolecular complex | 0.0252515601205765 |
GO:0022414 | reproductive process | 0.0252515601205765 |
GO:0031016 | pancreas development | 0.0252515601205765 |
GO:0048546 | digestive tract morphogenesis | 0.0252515601205765 |
GO:0008013 | beta-catenin binding | 0.0252515601205765 |
GO:0021510 | spinal cord development | 0.0252515601205765 |
GO:0048566 | embryonic gut development | 0.0252515601205765 |
GO:0043009 | chordate embryonic development | 0.0279603966352863 |
GO:0006139 | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 0.0279603966352863 |
GO:0005634 | nucleus | 0.0279603966352863 |
GO:0009792 | embryonic development ending in birth or egg hatching | 0.0279603966352863 |
GO:0045893 | positive regulation of transcription, DNA-dependent | 0.0304411520484539 |
GO:0008584 | male gonad development | 0.0304411520484539 |
GO:0045104 | intermediate filament cytoskeleton organization and biogenesis | 0.0304411520484539 |
GO:0048565 | gut development | 0.0315282952979028 |
GO:0021983 | pituitary gland development | 0.0315282952979028 |
GO:0048522 | positive regulation of cellular process | 0.0316878699685432 |
GO:0045103 | intermediate filament-based process | 0.0339144268905584 |
GO:0021536 | diencephalon development | 0.0339144268905584 |
GO:0050794 | regulation of cellular process | 0.0345197171976509 |
GO:0048663 | neuron fate commitment | 0.0345197171976509 |
GO:0048562 | embryonic organ morphogenesis | 0.0345197171976509 |
GO:0001569 | patterning of blood vessels | 0.0352874234836048 |
GO:0030182 | neuron differentiation | 0.0352874234836048 |
GO:0046546 | development of primary male sexual characteristics | 0.0352874234836048 |
GO:0001755 | neural crest cell migration | 0.0352874234836048 |
GO:0001708 | cell fate specification | 0.0352874234836048 |
GO:0022037 | metencephalon development | 0.0352874234836048 |
GO:0021549 | cerebellum development | 0.0352874234836048 |
GO:0045941 | positive regulation of transcription | 0.0353485326005872 |
GO:0044446 | intracellular organelle part | 0.0353485326005872 |
GO:0044422 | organelle part | 0.0355287354903787 |
GO:0045935 | positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 0.0358394842372895 |
GO:0007405 | neuroblast proliferation | 0.0380557864250218 |
GO:0048518 | positive regulation of biological process | 0.038807272896201 |
GO:0046661 | male sex differentiation | 0.038807272896201 |
GO:0043234 | protein complex | 0.040766909804769 |
GO:0014032 | neural crest cell development | 0.044730866457295 |
GO:0014033 | neural crest cell differentiation | 0.044730866457295 |
GO:0050789 | regulation of biological process | 0.0478167343296462 |
GO:0008585 | female gonad development | 0.0478167343296462 |
GO:0031325 | positive regulation of cellular metabolic process | 0.0478167343296462 |
GO:0046545 | development of primary female sexual characteristics | 0.048179540675391 |
GO:0046660 | female sex differentiation | 0.048179540675391 |
GO:0048869 | cellular developmental process | 0.0483030116227162 |
GO:0030154 | cell differentiation | 0.0483030116227162 |
GO:0048568 | embryonic organ development | 0.0483040050205813 |
GO:0010001 | glial cell differentiation | 0.0491965075188036 |
GO:0009893 | positive regulation of metabolic process | 0.0492916010723291 |
GO:0048762 | mesenchymal cell differentiation | 0.0492916010723291 |
GO:0014031 | mesenchymal cell development | 0.0492916010723291 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>
Ontology term | p-value | n |
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Ontology term | p-value | n |
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Ontology term | p-value | n |
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TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
{{{tfbs_overrepresentation_jaspar}}} |