MCL coexpression mm9:715

Phase1 CAGE Peaks

	Short description
Mm9::chr11:75252977..75252988,-	p3@Serpinf2
Mm9::chr18:63851871..63851882,-	p8@Txnl1
Mm9::chr19:55201670..55201733,-	p2@Gpam
Mm9::chr19:55201737..55201747,-	p7@Gpam
Mm9::chr1:191993385..191993405,-	p3@Prox1
Mm9::chr4:53156896..53156909,-	p@chr4:53156896..53156909 -
Mm9::chr4:53156932..53156960,-	p@chr4:53156932..53156960 -
Mm9::chr4:53156963..53156983,-	p@chr4:53156963..53156983 -
Mm9::chr9:110892955..110892970,-	p@chr9:110892955..110892970 -
Mm9::chr9:83148047..83148062,-	p@chr9:83148047..83148062 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

---

GO ID	GO name	FDR corrected p-value
GO:0004366	glycerol-3-phosphate O-acyltransferase activity	0.0294286461931374
GO:0006644	phospholipid metabolic process	0.0294286461931374
GO:0045332	phospholipid translocation	0.0294286461931374
GO:0006643	membrane lipid metabolic process	0.0294286461931374
GO:0033344	cholesterol efflux	0.0385563249146321
GO:0001945	lymph vessel development	0.0401584375282003

Relative expression of the co-expression cluster over median <br>Analyst:

---

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

---

Uber Anatomy

Ontology term	p-value	n
liver	7.65e-20	22
epithelial sac	7.65e-20	22
digestive gland	7.65e-20	22
epithelium of foregut-midgut junction	7.65e-20	22
anatomical boundary	7.65e-20	22
hepatobiliary system	7.65e-20	22
foregut-midgut junction	7.65e-20	22
hepatic diverticulum	7.65e-20	22
liver primordium	7.65e-20	22
septum transversum	7.65e-20	22
liver bud	7.65e-20	22
digestive tract diverticulum	1.46e-18	23
sac	1.46e-18	23
exocrine gland	8.98e-18	25
exocrine system	8.98e-18	25
abdomen element	2.50e-16	49
abdominal segment element	2.50e-16	49
abdominal segment of trunk	2.50e-16	49
abdomen	2.50e-16	49
trunk region element	8.01e-13	79
subdivision of trunk	1.19e-12	66
trunk mesenchyme	1.31e-12	45
mesenchyme	3.25e-11	61
entire embryonic mesenchyme	3.25e-11	61
trunk	2.14e-09	90
epithelial tube	2.23e-08	47

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

---

Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
{{{tfbs_overrepresentation_jaspar}}}