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MCL coexpression mm9:859

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:128227959..128228024,+p1@Mmp19
Mm9::chr13:4058917..4058918,+p@chr13:4058917..4058918
+
Mm9::chr1:182926224..182926235,-p@chr1:182926224..182926235
-
Mm9::chr1:182932030..182932048,-p@chr1:182932030..182932048
-
Mm9::chr1:182947620..182947679,-p1@Ephx1
Mm9::chr1:58086799..58086818,+p1@Aox1
Mm9::chr6:124462731..124462753,+p1@C1rb
Mm9::chr6:124492299..124492325,-p1@C1s


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:00470423-alpha-hydroxysteroid dehydrogenase (B-specific) activity0.0163146808650638
GO:0003816complement component C1s activity0.0163146808650638
GO:0004301epoxide hydrolase activity0.0163146808650638
GO:0004031aldehyde oxidase activity0.0163146808650638
GO:0016803ether hydrolase activity0.0163146808650638
GO:0016623oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor0.0163146808650638
GO:0004463leukotriene-A4 hydrolase activity0.0163146808650638
GO:0016801hydrolase activity, acting on ether bonds0.0285413070423536
GO:0030151molybdenum ion binding0.0300840475642867
GO:0006805xenobiotic metabolic process0.0300840475642867
GO:0019439aromatic compound catabolic process0.0300840475642867
GO:00515372 iron, 2 sulfur cluster binding0.0300840475642867
GO:0009410response to xenobiotic stimulus0.0300840475642867
GO:0030574collagen catabolic process0.0300840475642867
GO:0044259multicellular organismal macromolecule metabolic process0.0300840475642867
GO:0044268multicellular organismal protein metabolic process0.0300840475642867
GO:0044256protein digestion0.0300840475642867
GO:0044254multicellular organismal protein catabolic process0.0300840475642867
GO:0044266multicellular organismal macromolecule catabolic process0.0300840475642867
GO:0044243multicellular organismal catabolic process0.0300840475642867
GO:0032963collagen metabolic process0.0300840475642867
GO:0004175endopeptidase activity0.0300840475642867
GO:0009636response to toxin0.0300840475642867
GO:0044236multicellular organismal metabolic process0.0300840475642867
GO:0016229steroid dehydrogenase activity0.031913762660244
GO:0051287NAD binding0.0321440404871541
GO:0009056catabolic process0.0393149711488276
GO:0006958complement activation, classical pathway0.0393149711488276
GO:0002455humoral immune response mediated by circulating immunoglobulin0.0428880772729188
GO:0006508proteolysis0.0428880772729188
GO:0016903oxidoreductase activity, acting on the aldehyde or oxo group of donors0.0428880772729188
GO:0005615extracellular space0.0428880772729188
GO:0007586digestion0.0428880772729188
GO:0006956complement activation0.0428880772729188
GO:0002541activation of plasma proteins during acute inflammatory response0.0428880772729188
GO:0016787hydrolase activity0.0428880772729188
GO:0051536iron-sulfur cluster binding0.0428880772729188
GO:0051540metal cluster binding0.0428880772729188
GO:0008233peptidase activity0.0434545151844588
GO:0044421extracellular region part0.0434545151844588



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
trunk mesenchyme1.45e-1345
trunk4.80e-1390
immaterial anatomical entity5.32e-1179
trunk region element1.41e-1079
mesenchyme1.43e-1061
entire embryonic mesenchyme1.43e-1061
subdivision of trunk2.49e-0966
exocrine gland8.94e-0925
exocrine system8.94e-0925
epithelial tube1.70e-0847
liver5.08e-0822
epithelial sac5.08e-0822
digestive gland5.08e-0822
epithelium of foregut-midgut junction5.08e-0822
anatomical boundary5.08e-0822
hepatobiliary system5.08e-0822
foregut-midgut junction5.08e-0822
hepatic diverticulum5.08e-0822
liver primordium5.08e-0822
septum transversum5.08e-0822
liver bud5.08e-0822
abdomen element7.24e-0849
abdominal segment element7.24e-0849
abdominal segment of trunk7.24e-0849
abdomen7.24e-0849
digestive tract diverticulum1.05e-0723
sac1.05e-0723
organism subdivision4.31e-07150


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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