MCL coexpression mm9:2280
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr1:123224249..123224267,- | p9@Insig2 |
| Mm9::chr2:110154372..110154384,- | p7@Bbox1 |
| Mm9::chr2:110154391..110154403,- | p9@Bbox1 |
| Mm9::chr2:110154423..110154449,- | p6@Bbox1 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0008336 | gamma-butyrobetaine dioxygenase activity | 0.00423663040837316 |
| GO:0006991 | response to sterol depletion | 0.00423663040837316 |
| GO:0045329 | carnitine biosynthetic process | 0.00423663040837316 |
| GO:0009437 | carnitine metabolic process | 0.00635459742497994 |
| GO:0042401 | biogenic amine biosynthetic process | 0.0254016766960898 |
| GO:0016706 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | 0.0254016766960898 |
| GO:0042398 | amino acid derivative biosynthetic process | 0.0254016766960898 |
| GO:0006767 | water-soluble vitamin metabolic process | 0.0283527507694216 |
| GO:0009309 | amine biosynthetic process | 0.0283527507694216 |
| GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | 0.0283527507694216 |
| GO:0051213 | dioxygenase activity | 0.0283527507694216 |
| GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen | 0.0283527507694216 |
| GO:0006766 | vitamin metabolic process | 0.0283527507694216 |
| GO:0008203 | cholesterol metabolic process | 0.0283527507694216 |
| GO:0016125 | sterol metabolic process | 0.0283527507694216 |
| GO:0006576 | biogenic amine metabolic process | 0.0283527507694216 |
| GO:0044271 | nitrogen compound biosynthetic process | 0.0283527507694216 |
| GO:0006575 | amino acid derivative metabolic process | 0.03064404692869 |
| GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | 0.0416679741868591 |
| GO:0008202 | steroid metabolic process | 0.044316444686879 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| exocrine gland | 6.31e-12 | 25 |
| exocrine system | 6.31e-12 | 25 |
| liver | 2.02e-10 | 22 |
| epithelial sac | 2.02e-10 | 22 |
| digestive gland | 2.02e-10 | 22 |
| epithelium of foregut-midgut junction | 2.02e-10 | 22 |
| anatomical boundary | 2.02e-10 | 22 |
| hepatobiliary system | 2.02e-10 | 22 |
| foregut-midgut junction | 2.02e-10 | 22 |
| hepatic diverticulum | 2.02e-10 | 22 |
| liver primordium | 2.02e-10 | 22 |
| septum transversum | 2.02e-10 | 22 |
| liver bud | 2.02e-10 | 22 |
| digestive tract diverticulum | 8.71e-10 | 23 |
| sac | 8.71e-10 | 23 |
| zone of skin | 1.29e-08 | 5 |
| skin epidermis | 1.29e-08 | 5 |
| skin of body | 1.29e-08 | 5 |
| integument | 1.29e-08 | 5 |
| surface | 1.29e-08 | 5 |
| outer epithelium | 1.29e-08 | 5 |
| integumental system | 1.29e-08 | 5 |
| enveloping layer of ectoderm | 1.29e-08 | 5 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.600426 |
| MA0004.1 | 0.6888 |
| MA0006.1 | 0.497533 |
| MA0007.1 | 0.672186 |
| MA0009.1 | 1.15569 |
| MA0014.1 | 0.0809287 |
| MA0017.1 | 0.528196 |
| MA0019.1 | 0.964875 |
| MA0024.1 | 1.11019 |
| MA0025.1 | 1.39562 |
| MA0027.1 | 2.81824 |
| MA0028.1 | 0.509589 |
| MA0029.1 | 1.08753 |
| MA0030.1 | 1.09438 |
| MA0031.1 | 1.05719 |
| MA0038.1 | 1.97232 |
| MA0040.1 | 4.2615 |
| MA0041.1 | 0.604221 |
| MA0042.1 | 0.589368 |
| MA0043.1 | 1.25564 |
| MA0046.1 | 1.1929 |
| MA0048.1 | 1.35097 |
| MA0050.1 | 0.731539 |
| MA0051.1 | 0.856094 |
| MA0052.1 | 1.17701 |
| MA0055.1 | 1.28762 |
| MA0056.1 | 0 |
| MA0057.1 | 0.251896 |
| MA0058.1 | 0.581673 |
| MA0059.1 | 0.59559 |
| MA0060.1 | 0.403071 |
| MA0061.1 | 0.438628 |
| MA0063.1 | 0 |
| MA0066.1 | 0.834648 |
| MA0067.1 | 1.50873 |
| MA0068.1 | 0.256913 |
| MA0069.1 | 1.17737 |
| MA0070.1 | 1.16732 |
| MA0071.1 | 0.73062 |
| MA0072.1 | 1.15853 |
| MA0073.1 | 0.0471131 |
| MA0074.1 | 0.795862 |
| MA0076.1 | 1.35592 |
| MA0077.1 | 1.13603 |
| MA0078.1 | 0.891476 |
| MA0081.1 | 0.621611 |
| MA0083.1 | 1.25482 |
| MA0084.1 | 1.84013 |
| MA0087.1 | 1.21037 |
| MA0088.1 | 0.582815 |
| MA0089.1 | 0 |
| MA0090.1 | 0.650768 |
| MA0091.1 | 0.703314 |
| MA0092.1 | 0.651119 |
| MA0093.1 | 0.519148 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.783305 |
| MA0101.1 | 0.605676 |
| MA0103.1 | 2.29453 |
| MA0105.1 | 0.313353 |
| MA0106.1 | 0.899777 |
| MA0107.1 | 0.533522 |
| MA0108.2 | 0.989014 |
| MA0109.1 | 0 |
| MA0111.1 | 0.666525 |
| MA0113.1 | 0.869608 |
| MA0114.1 | 1.11164 |
| MA0115.1 | 1.25852 |
| MA0116.1 | 0.497293 |
| MA0117.1 | 1.22527 |
| MA0119.1 | 0.606338 |
| MA0122.1 | 1.24573 |
| MA0124.1 | 1.45461 |
| MA0125.1 | 1.37907 |
| MA0130.1 | 0 |
| MA0131.1 | 0.960068 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.29308 |
| MA0136.1 | 0.817395 |
| MA0139.1 | 0.365453 |
| MA0140.1 | 0.78318 |
| MA0141.1 | 0.563066 |
| MA0142.1 | 1.04199 |
| MA0143.1 | 0.887119 |
| MA0144.1 | 0.439506 |
| MA0145.1 | 0.21199 |
| MA0146.1 | 0.0944145 |
| MA0147.1 | 0.453952 |
| MA0148.1 | 0.706718 |
| MA0149.1 | 0.611881 |
| MA0062.2 | 0.856416 |
| MA0035.2 | 0.788288 |
| MA0039.2 | 0.0959929 |
| MA0138.2 | 0.951653 |
| MA0002.2 | 0.368961 |
| MA0137.2 | 0.559766 |
| MA0104.2 | 0.386166 |
| MA0047.2 | 0.845655 |
| MA0112.2 | 0.211985 |
| MA0065.2 | 0.609584 |
| MA0150.1 | 0.67206 |
| MA0151.1 | 0 |
| MA0152.1 | 0.84577 |
| MA0153.1 | 1.31015 |
| MA0154.1 | 0.263609 |
| MA0155.1 | 0.230016 |
| MA0156.1 | 0.549102 |
| MA0157.1 | 1.0083 |
| MA0158.1 | 0 |
| MA0159.1 | 2.0472 |
| MA0160.1 | 0.71003 |
| MA0161.1 | 0 |
| MA0162.1 | 0.346529 |
| MA0163.1 | 0.0996272 |
| MA0164.1 | 0.817786 |
| MA0080.2 | 0.534538 |
| MA0018.2 | 0.828253 |
| MA0099.2 | 0.944966 |
| MA0079.2 | 0.0553806 |
| MA0102.2 | 1.8929 |
| MA0258.1 | 0.419871 |
| MA0259.1 | 0.441366 |
| MA0442.1 | 0 |
