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UBERON:0000007

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Name:pituitary gland
Definition:"The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands [GO]. An endocrine gland located ventral to the diencephalon and derived from mixed neuroectodermal and non neuroectodermal origin [ZFIN]." [Wikipedia:Pituitary_gland, ZFIN:curator]
Xrefs:
links:

AAO:0010536
BM:Die-Hy-HY
BTO:0001073
EFO:0000857
EHDAA:2183
EHDAA:4477
EHDAA2:0001471
EMAPA:16647
EMAPA:16898
EV:0100132
FMA:13889
GAID:457
[ 200px-Gray1180.png 200px-Gray1180.png]
MA:0000176
MAT:0000077
MESH:A.06.407.747
MIAA:0000077
ncithesaurus:Pituitary_Gland
NIF_GrossAnatomy:birnlex_1353
OpenCyc:Mx4rv6NQYJwpEbGdrcN5Y29ycA
SCTID:181125003
TAO:0000118
VHOG:0000143
XAO:0000017

ZFA:0000118
Synonyms: "glandula pituitaria" RELATED [BTO:0001073]
"hypophysis" RELATED [ZFA:0000118]
"hypophysis cerebri" RELATED [MA:0000176]
"pituitary" EXACT [BTO:0001073]
"pituitary body" EXACT [BTO:0001073]
Comments:Taxon notes: The lamprey possesses a distinct pituitary organ and hormones, the ascidian does not show distinct evidence of them [Sower S, Freamat M, Kavanaugh S. The origins of the vertebrate hypothalamic窶菟ituitary窶堵onadal (HPG) and hypothalamic窶菟ituitary窶鍍hyroid (HPT) endocrine systems: new insights from lampreys. Gen Comp Endocrinol 2009;161:20-9]
Subset: organ_slim
uberon_slim
vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:UBERON:0002368(endocrine gland),UBERON:0003296(gland of diencephalon),UBERON:0010133(neuroendocrine gland)
develops_from:UBERON:0000924(ectoderm)
part_of:UBERON:0001894(diencephalon)



Children

derives from:FF:0010162 (human pituitary gland - adult sample),FF:0011303 (mouse pituitary gland- adult sample),FF:0011317 (mouse pituitary gland- embryo E12 sample),FF:0011325 (mouse pituitary gland- embryo E13 sample),FF:0011334 (mouse pituitary gland- embryo E14 sample),FF:0011345 (mouse pituitary gland- embryo E15 sample),FF:0011353 (mouse pituitary gland- embryo E16 sample),FF:0011507 (mouse pituitary gland- neonate N00 sample),FF:0011519 (mouse pituitary gland- embryo E17 sample)
part of:FF:0000114 (mouse pituitary cell),UBERON:0002196 (adenohypophysis)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology


Human (Homo sapiens)

... further results Mouse (Mus musculus)

... further results


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0000007 (pituitary gland), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data


P-valueFFCPShort description
3.29e-195FFCP PHASE1:Hg19::chr1:168250194..168250197,+#_47bedeeeae192cbe89ab07ee58e0dcb1p3@TBX19
3.29e-195FFCP PHASE1:Hg19::chr5:158737729..158737738,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr5:158737729..158737738, -
3.29e-195FFCP PHASE2:Hg19::chr17:61996252..61996253,-#_47bedeeeae192cbe89ab07ee58e0dcb1p2@GH1, p3@CSHL1
3.29e-195FFCP PHASE2:Hg19::chr3:130248948..130248959,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr3:130248948..130248959, +
3.29e-195FFCP PHASE1:Hg19::chr17:61995410..61995414,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr17:61995410..61995414, -
3.29e-195FFCP PHASE2:Hg19::chr7:31003580..31003589,+#_47bedeeeae192cbe89ab07ee58e0dcb1p6@GHRHR
3.29e-195FFCP PHASE2:Hg19::chr19:7979665..7979675,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr19:7979665..7979675, +
3.29e-195FFCP PHASE2:Hg19::chr17:61995704..61995739,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr17:61995704..61995739, +
3.29e-195FFCP PHASE2:Hg19::chr6:22287815..22287820,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22287815..22287820, -
3.29e-195FFCP PHASE2:Hg19::chr19:2608406..2608413,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr19:2608406..2608413, -
3.29e-195FFCP PHASE2:Hg19::chr17:61994760..61994767,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr17:61994760..61994767, +
3.29e-195FFCP PHASE1:Hg19::chr2:7497646..7497649,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr2:7497646..7497649, +
3.29e-195FFCP PHASE2:Hg19::chr6:22287647..22287662,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22287647..22287662, -
3.29e-195FFCP PHASE1:Hg19::chr10:123959529..123959547,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr10:123959529..123959547, +
3.29e-195FFCP PHASE1:Hg19::chr12:89881337..89881342,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr12:89881337..89881342, -
3.29e-195FFCP PHASE1:Hg19::chr7:31003593..31003614,+#_47bedeeeae192cbe89ab07ee58e0dcb1p2@GHRHR
3.29e-195FFCP PHASE1:Hg19::chr17:61995906..61995914,-#_47bedeeeae192cbe89ab07ee58e0dcb1p6@AB591020
3.29e-195FFCP PHASE1:Hg19::chr4:1352813..1352818,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr4:1352813..1352818, -
3.29e-195FFCP PHASE2:Hg19::chr17:61996018..61996019,-#_47bedeeeae192cbe89ab07ee58e0dcb1p5@AB591020
3.29e-195FFCP PHASE2:Hg19::chr6:22290499..22290506,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22290499..22290506, +
3.29e-195FFCP PHASE1:Hg19::chr16:21049173..21049231,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr16:21049173..21049231, -
3.29e-195FFCP PHASE1:Hg19::chr6:22294730..22294743,-#_47bedeeeae192cbe89ab07ee58e0dcb1p6@PRL
3.29e-195FFCP PHASE2:Hg19::chrX:9528518..9528536,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chrX:9528518..9528536, +
3.29e-195FFCP PHASE1:Hg19::chrX:54051809..54051811,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chrX:54051809..54051811, +
3.29e-195FFCP PHASE2:Hg19::chr17:61995371..61995384,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr17:61995371..61995384, +
3.29e-195FFCP PHASE1:Hg19::chr3:154042775..154042780,-#_47bedeeeae192cbe89ab07ee58e0dcb1p8@DHX36
3.29e-195FFCP PHASE2:Hg19::chr6:22287728..22287735,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22287728..22287735, -
3.29e-195FFCP PHASE1:Hg19::chr2:25391425..25391439,-#_47bedeeeae192cbe89ab07ee58e0dcb1p10@POMC
3.29e-195FFCP PHASE1:Hg19::chr6:22290447..22290450,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22290447..22290450, -
3.29e-195FFCP PHASE1:Hg19::chr2:211830430..211830435,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr2:211830430..211830435, +
3.29e-195FFCP PHASE1:Hg19::chr6:22287695..22287700,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22287695..22287700, -
3.29e-195FFCP PHASE1:Hg19::chr17:61996160..61996176,-#_47bedeeeae192cbe89ab07ee58e0dcb1p3@GH1
3.29e-195FFCP PHASE1:Hg19::chr11:70178863..70178874,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr11:70178863..70178874, +
3.29e-195FFCP PHASE1:Hg19::chr8:107844170..107844179,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr8:107844170..107844179, +
3.29e-195FFCP PHASE2:Hg19::chr17:61996393..61996421,-#_47bedeeeae192cbe89ab07ee58e0dcb1p4@CSHL1, p4@GH1
3.29e-195FFCP PHASE2:Hg19::chr6:22294718..22294725,-#_47bedeeeae192cbe89ab07ee58e0dcb1p11@PRL
3.29e-195FFCP PHASE1:Hg19::chr17:61995432..61995458,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr17:61995432..61995458, -
3.29e-195FFCP PHASE2:Hg19::chr7:31003593..31003614,+#_47bedeeeae192cbe89ab07ee58e0dcb1p2@GHRHR
3.29e-195FFCP PHASE2:Hg19::chr6:22290440..22290455,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22290440..22290455, +
3.29e-195FFCP PHASE1:Hg19::chr2:25391815..25391821,-#_47bedeeeae192cbe89ab07ee58e0dcb1p13@POMC
3.29e-195FFCP PHASE1:Hg19::chr6:22292828..22292837,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22292828..22292837, -
3.29e-195FFCP PHASE1:Hg19::chr3:130248877..130248886,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr3:130248877..130248886, +
3.29e-195FFCP PHASE2:Hg19::chr17:61994797..61994839,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr17:61994797..61994839, -
3.29e-195FFCP PHASE2:Hg19::chr6:22287669..22287676,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22287669..22287676, -
3.29e-195FFCP PHASE2:Hg19::chr3:118521917..118521922,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr3:118521917..118521922, -
3.29e-195FFCP PHASE2:Hg19::chr17:18021982..18021985,+#_47bedeeeae192cbe89ab07ee58e0dcb1p3@MYO15A
3.29e-195FFCP PHASE2:Hg19::chr4:68620100..68620112,-#_47bedeeeae192cbe89ab07ee58e0dcb1p1@GNRHR
3.29e-195FFCP PHASE1:Hg19::chr6:22287768..22287781,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22287768..22287781, -
3.29e-195FFCP PHASE2:Hg19::chr5:158737729..158737738,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr5:158737729..158737738, -
3.29e-195FFCP PHASE1:Hg19::chr12:89881348..89881356,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr12:89881348..89881356, -
3.29e-195FFCP PHASE1:Hg19::chr7:31003621..31003641,+#_47bedeeeae192cbe89ab07ee58e0dcb1p3@GHRHR
3.29e-195FFCP PHASE2:Hg19::chr1:168250194..168250197,+#_47bedeeeae192cbe89ab07ee58e0dcb1p3@TBX19
3.29e-195FFCP PHASE1:Hg19::chr17:61995979..61995990,-#_47bedeeeae192cbe89ab07ee58e0dcb1p2@AB591020
3.29e-195FFCP PHASE1:Hg19::chr19:49519357..49519372,-#_47bedeeeae192cbe89ab07ee58e0dcb1p1@CU678753
3.29e-195FFCP PHASE1:Hg19::chr6:22294755..22294768,-#_47bedeeeae192cbe89ab07ee58e0dcb1p9@PRL
3.29e-195FFCP PHASE2:Hg19::chr2:211830430..211830435,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr2:211830430..211830435, +
3.29e-195FFCP PHASE2:Hg19::chr17:61996155..61996158,-#_47bedeeeae192cbe89ab07ee58e0dcb1p5@GH1
3.29e-195FFCP PHASE2:Hg19::chr11:70178863..70178874,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr11:70178863..70178874, +
3.29e-195FFCP PHASE1:Hg19::chr17:61995207..61995219,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr17:61995207..61995219, -
3.29e-195FFCP PHASE1:Hg19::chrX:38147077..38147085,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chrX:38147077..38147085, -
3.29e-195FFCP PHASE1:Hg19::chr8:1066886..1066919,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr8:1066886..1066919, +
3.29e-195FFCP PHASE2:Hg19::chr17:61995410..61995414,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr17:61995410..61995414, -
3.29e-195FFCP PHASE1:Hg19::chr3:87325636..87325643,-#_47bedeeeae192cbe89ab07ee58e0dcb1p2@POU1F1
3.29e-195FFCP PHASE2:Hg19::chr2:7497646..7497649,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr2:7497646..7497649, +
3.29e-195FFCP PHASE1:Hg19::chr13:78813679..78813681,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr13:78813679..78813681, -
3.29e-195FFCP PHASE1:Hg19::chr2:211830446..211830457,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr2:211830446..211830457, +
3.29e-195FFCP PHASE1:Hg19::chr6:22287710..22287718,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22287710..22287718, -
3.29e-195FFCP PHASE1:Hg19::chr9:135964996..135965001,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr9:135964996..135965001, +
3.29e-195FFCP PHASE2:Hg19::chr6:22294730..22294743,-#_47bedeeeae192cbe89ab07ee58e0dcb1p6@PRL
3.29e-195FFCP PHASE2:Hg19::chr10:123959529..123959547,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr10:123959529..123959547, +
3.29e-195FFCP PHASE1:Hg19::chr17:61995480..61995499,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr17:61995480..61995499, -
3.29e-195FFCP PHASE2:Hg19::chr4:1352813..1352818,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr4:1352813..1352818, -
3.29e-195FFCP PHASE2:Hg19::chr7:31003621..31003641,+#_47bedeeeae192cbe89ab07ee58e0dcb1p3@GHRHR
3.29e-195FFCP PHASE2:Hg19::chr2:25391425..25391439,-#_47bedeeeae192cbe89ab07ee58e0dcb1p10@POMC
3.29e-195FFCP PHASE1:Hg19::chr3:4774755..4774765,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr3:4774755..4774765, +
3.29e-195FFCP PHASE2:Hg19::chr17:61995906..61995914,-#_47bedeeeae192cbe89ab07ee58e0dcb1p6@AB591020
3.29e-195FFCP PHASE2:Hg19::chr6:22290447..22290450,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22290447..22290450, -
3.29e-195FFCP PHASE1:Hg19::chr17:61994613..61994649,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr17:61994613..61994649, -
3.29e-195FFCP PHASE2:Hg19::chrX:54051809..54051811,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chrX:54051809..54051811, +
3.29e-195FFCP PHASE2:Hg19::chr3:154042775..154042780,-#_47bedeeeae192cbe89ab07ee58e0dcb1p8@DHX36
3.29e-195FFCP PHASE2:Hg19::chr6:22287695..22287700,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22287695..22287700, -
3.29e-195FFCP PHASE1:Hg19::chr6:22287787..22287798,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22287787..22287798, -
3.29e-195FFCP PHASE1:Hg19::chr19:49519519..49519562,-#_47bedeeeae192cbe89ab07ee58e0dcb1p2@CU678753
3.29e-195FFCP PHASE1:Hg19::chr8:126582844..126582849,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr8:126582844..126582849, -
3.29e-195FFCP PHASE1:Hg19::chr2:241080084..241080093,-#_47bedeeeae192cbe89ab07ee58e0dcb1p5@OTOS
3.29e-195FFCP PHASE1:Hg19::chr7:31006649..31006651,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr7:31006649..31006651, +
3.29e-195FFCP PHASE2:Hg19::chr8:107844170..107844179,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr8:107844170..107844179, +
3.29e-195FFCP PHASE1:Hg19::chr6:22287619..22287636,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22287619..22287636, -
3.29e-195FFCP PHASE1:Hg19::chr17:61995995..61996002,-#_47bedeeeae192cbe89ab07ee58e0dcb1p3@AB591020
3.29e-195FFCP PHASE1:Hg19::chr3:133115455..133115457,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr3:133115455..133115457, +
3.29e-195FFCP PHASE1:Hg19::chr1:240043364..240043366,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr1:240043364..240043366, +
3.29e-195FFCP PHASE2:Hg19::chr2:25391815..25391821,-#_47bedeeeae192cbe89ab07ee58e0dcb1p13@POMC
3.29e-195FFCP PHASE2:Hg19::chr2:211830446..211830457,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr2:211830446..211830457, +
3.29e-195FFCP PHASE2:Hg19::chr17:61996160..61996176,-#_47bedeeeae192cbe89ab07ee58e0dcb1p3@GH1
3.29e-195FFCP PHASE2:Hg19::chr6:22292828..22292837,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22292828..22292837, -
3.29e-195FFCP PHASE2:Hg19::chr3:130248877..130248886,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr3:130248877..130248886, +
3.29e-195FFCP PHASE1:Hg19::chr17:61995220..61995244,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr17:61995220..61995244, -
3.29e-195FFCP PHASE2:Hg19::chr12:89881337..89881342,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr12:89881337..89881342, -
3.29e-195FFCP PHASE2:Hg19::chr17:61995432..61995458,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr17:61995432..61995458, -
3.29e-195FFCP PHASE2:Hg19::chr6:22287768..22287781,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22287768..22287781, -