MCL coexpression mm9:1652

Phase1 CAGE Peaks

	Short description
Mm9::chr13:64208489..64208500,-	p@chr13:64208489..64208500 -
Mm9::chr19:39585397..39585408,+	p@chr19:39585397..39585408 +
Mm9::chr9:107571298..107571326,-	p2@Slc38a3
Mm9::chr9:107571330..107571351,-	p3@Slc38a3
Mm9::chr9:57529711..57529721,-	p@chr9:57529711..57529721 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0015817	histidine transport	0.00378009695919502
GO:0005290	L-histidine transmembrane transporter activity	0.00378009695919502
GO:0006868	glutamine transport	0.00378009695919502
GO:0015186	L-glutamine transmembrane transporter activity	0.00378009695919502
GO:0015802	basic amino acid transport	0.00453599208408744
GO:0015174	basic amino acid transmembrane transporter activity	0.00503985313015651
GO:0015179	L-amino acid transmembrane transporter activity	0.0239170033550514
GO:0050381	unspecific monooxygenase activity	0.0239170033550514
GO:0005275	amine transmembrane transporter activity	0.0239170033550514
GO:0015171	amino acid transmembrane transporter activity	0.0239170033550514
GO:0015297	antiporter activity	0.0239170033550514
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	0.0239170033550514
GO:0006865	amino acid transport	0.0251606048229574
GO:0015837	amine transport	0.0251606048229574
GO:0046943	carboxylic acid transmembrane transporter activity	0.0251606048229574
GO:0005342	organic acid transmembrane transporter activity	0.0251606048229574
GO:0046942	carboxylic acid transport	0.0251606048229574
GO:0015849	organic acid transport	0.0251606048229574
GO:0031402	sodium ion binding	0.0321605473897005
GO:0020037	heme binding	0.0383722774646922
GO:0046906	tetrapyrrole binding	0.0383722774646922
GO:0006814	sodium ion transport	0.0383722774646922
GO:0004497	monooxygenase activity	0.0392433291371927
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	0.0392433291371927
GO:0015293	symporter activity	0.04007589144515
GO:0005792	microsome	0.0437744587016852
GO:0042598	vesicular fraction	0.0437744587016852
GO:0015291	secondary active transmembrane transporter activity	0.0459220359461313
GO:0031420	alkali metal ion binding	0.0459220359461313

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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