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MCL coexpression mm9:1652

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Phase1 CAGE Peaks

  Short description
Mm9::chr13:64208489..64208500,- p@chr13:64208489..64208500
-
Mm9::chr19:39585397..39585408,+ p@chr19:39585397..39585408
+
Mm9::chr9:107571298..107571326,- p2@Slc38a3
Mm9::chr9:107571330..107571351,- p3@Slc38a3
Mm9::chr9:57529711..57529721,- p@chr9:57529711..57529721
-


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


GO IDGO nameFDR corrected p-value
GO:0015817histidine transport0.00378009695919502
GO:0005290L-histidine transmembrane transporter activity0.00378009695919502
GO:0006868glutamine transport0.00378009695919502
GO:0015186L-glutamine transmembrane transporter activity0.00378009695919502
GO:0015802basic amino acid transport0.00453599208408744
GO:0015174basic amino acid transmembrane transporter activity0.00503985313015651
GO:0015179L-amino acid transmembrane transporter activity0.0239170033550514
GO:0050381unspecific monooxygenase activity0.0239170033550514
GO:0005275amine transmembrane transporter activity0.0239170033550514
GO:0015171amino acid transmembrane transporter activity0.0239170033550514
GO:0015297antiporter activity0.0239170033550514
GO:0016712oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen0.0239170033550514
GO:0006865amino acid transport0.0251606048229574
GO:0015837amine transport0.0251606048229574
GO:0046943carboxylic acid transmembrane transporter activity0.0251606048229574
GO:0005342organic acid transmembrane transporter activity0.0251606048229574
GO:0046942carboxylic acid transport0.0251606048229574
GO:0015849organic acid transport0.0251606048229574
GO:0031402sodium ion binding0.0321605473897005
GO:0020037heme binding0.0383722774646922
GO:0046906tetrapyrrole binding0.0383722774646922
GO:0006814sodium ion transport0.0383722774646922
GO:0004497monooxygenase activity0.0392433291371927
GO:0016705oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen0.0392433291371927
GO:0015293symporter activity0.04007589144515
GO:0005792microsome0.0437744587016852
GO:0042598vesicular fraction0.0437744587016852
GO:0015291secondary active transmembrane transporter activity0.0459220359461313
GO:0031420alkali metal ion binding0.0459220359461313



Relative expression of the co-expression cluster over median
Analyst:





Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data


Cell Type
Ontology termp-valuen
metabolising cell3.09e-125
endopolyploid cell3.09e-125
parenchymal cell3.09e-125
polyploid cell3.09e-125
hepatocyte3.09e-125

Uber Anatomy
Ontology termp-valuen
liver5.22e-3422
epithelial sac5.22e-3422
digestive gland5.22e-3422
epithelium of foregut-midgut junction5.22e-3422
anatomical boundary5.22e-3422
hepatobiliary system5.22e-3422
foregut-midgut junction5.22e-3422
hepatic diverticulum5.22e-3422
liver primordium5.22e-3422
septum transversum5.22e-3422
liver bud5.22e-3422
digestive tract diverticulum2.10e-3223
sac2.10e-3223
exocrine gland1.41e-2925
exocrine system1.41e-2925
trunk mesenchyme4.06e-1545
epithelial tube2.39e-1447
abdomen element1.22e-1349
abdominal segment element1.22e-1349
abdominal segment of trunk1.22e-1349
abdomen1.22e-1349
gut epithelium7.92e-1255
endocrine gland1.36e-1060
mesenchyme2.26e-1061
entire embryonic mesenchyme2.26e-1061
gland1.50e-0965
foregut1.63e-0980
unilaminar epithelium2.32e-0966
subdivision of trunk2.32e-0966
endo-epithelium7.96e-0969
endocrine system2.46e-0872
immaterial anatomical entity2.46e-0779
trunk region element2.46e-0779


TFBS overrepresentationSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.0833043
MA0004.10.603793
MA0006.10.419915
MA0007.10.587678
MA0009.11.06266
MA0014.10.0502051
MA0017.10.449113
MA0019.10.874061
MA0024.11.01759
MA0025.11.30092
MA0027.12.72141
MA0028.10.43138
MA0029.10.995171
MA0030.15.33409
MA0031.12.2151
MA0038.10.757669
MA0040.11.07552
MA0041.10.522007
MA0042.10.507715
MA0043.11.1618
MA0046.11.09955
MA0048.10.205696
MA0050.10.645342
MA0051.10.767098
MA0052.11.08379
MA0055.10.28842
MA0056.10
MA0057.10.192781
MA0058.10.50032
MA0059.10.513699
MA0060.10.330907
MA0061.10.364227
MA0063.10
MA0066.10.746072
MA0067.11.41352
MA0068.10.197245
MA0069.11.08414
MA0070.11.07418
MA0071.11.55428
MA0072.11.06547
MA0073.10.000589538
MA0074.10.708108
MA0076.10.470037
MA0077.11.04318
MA0078.10.801834
MA0081.10.53877
MA0083.11.16099
MA0084.11.74401
MA0087.11.11687
MA0088.10.148348
MA0089.10
MA0090.10.566938
MA0091.10.617887
MA0092.10.567278
MA0093.10.440484
MA0095.10
MA0098.10
MA0100.10.695835
MA0101.10.523409
MA0103.10.460936
MA0105.10.248108
MA0106.10.809991
MA0107.10.454197
MA0108.22.07761
MA0109.10
MA0111.10.582193
MA0113.10.780358
MA0114.10.949408
MA0115.11.16466
MA0116.10.419688
MA0117.11.13165
MA0119.11.30068
MA0122.11.15196
MA0124.11.35963
MA0125.11.28445
MA0130.10
MA0131.10.869325
MA0132.10
MA0133.10
MA0135.11.19898
MA0136.10.729175
MA0139.10.295945
MA0140.10.695713
MA0141.11.21195
MA0142.10.950155
MA0143.10.797553
MA0144.10.365053
MA0145.10.927481
MA0146.10.822925
MA0147.10.378658
MA0148.11.50563
MA0149.10.529387
MA0062.20.254018
MA0035.20.700704
MA0039.20.0102623
MA0138.20.861035
MA0002.20.299191
MA0137.20.479301
MA0104.20.315156
MA0047.22.98776
MA0112.20.157681
MA0065.21.48609
MA0150.11.43499
MA0151.10
MA0152.10.756973
MA0153.11.21594
MA0154.10.203217
MA0155.10.515751
MA0156.10.469089
MA0157.12.11652
MA0158.10
MA0159.10.389847
MA0160.11.51238
MA0161.10
MA0162.10.0699535
MA0163.10.0644585
MA0164.11.7313
MA0080.20.455167
MA0018.20.739807
MA0099.20.854449
MA0079.20.000313198
MA0102.21.79669
MA0258.10.91616
MA0259.10.366802
MA0442.10