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UBERON:0005426

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Name:lens vesicle
Definition:"Portion of tissue that gives rise to the lens." [https://sourceforge.net/tracker/?func
Xrefs:
links:

EHDAA2:0000983
EHDAA:4737
EMAPA:17163
SCTID:361510002
TAO:0002205
VHOG:0001163
ZFA:0001679

ZFIN:ZDB-ANAT-090226-2
Synonyms: "hollow lens vesicle" NARROW SENSU []
"solid lens vesicle" NARROW SENSU [ZFA:0001679]
Comments:Development notes: the lens of zebrafish (and other teleosts) forms from delamination of cells from the lens placode; thus, there is no formation of a hollow lens vesicle, in contrast to the situation in mammals and birds (Glass and Dahm, 2004) [PMID:16496288] The lens of the zebrafish forms by delamination of lens placodal cells and not through invagination. This results in a solid spherical mass as opposed to a hollow lens vesicle. Detachment of the solid lens vesicle of zebrafish at 24b26 hpf is accomplished in part by apoptosis, similar to mammals[ZFA]
Subset: vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:UBERON:0000479(tissue),UBERON:0004121(ectoderm-derived structure)
develops_from:UBERON:0003073(lens placode)



Children

develops from:UBERON:0000965 (lens of camera-type eye)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology




Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0005426 (lens vesicle), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data


P-valueFFCPShort description
1.41e-88FFCP PHASE2:Hg19::chr22:25595823..25595826,+#_9a1f49a9ba5170c6f5c3fe7553e681b0p1@CRYBB3
1.41e-88FFCP PHASE1:Hg19::chr22:25595823..25595826,+#_9a1f49a9ba5170c6f5c3fe7553e681b0p1@CRYBB3
3.32e-74FFCP PHASE2:Hg19::chr22:25615600..25615611,+#_ef95f245464de3d3006bb82bcf413c98p1@CRYBB2
3.32e-74FFCP PHASE1:Hg19::chr22:25615600..25615611,+#_ef95f245464de3d3006bb82bcf413c98p1@CRYBB2
5.48e-74FFCP PHASE1:Hg19::chr19:51891222..51891233,-#_288e6b96e734cec548834e2e6409fc1ap1@LIM2
5.48e-74FFCP PHASE2:Hg19::chr19:51891222..51891233,-#_288e6b96e734cec548834e2e6409fc1ap1@LIM2
3.8e-56FFCP PHASE2:Hg19::chr22:27017921..27017928,+#_ae6fdde5c3940669d781e7cdfc30f819p1@CRYBA4
3.8e-56FFCP PHASE1:Hg19::chr22:27017921..27017928,+#_ae6fdde5c3940669d781e7cdfc30f819p1@CRYBA4
3.1e-50FFCP PHASE1:Hg19::chr13:104778247..104778293,+#_dee81e90f40530db1ed9a0623fc6aab6p@chr13:104778247..104778293, +
3.1e-50FFCP PHASE2:Hg19::chr20:61204240..61204241,+#_dee81e90f40530db1ed9a0623fc6aab6p@chr20:61204240..61204241, +
3.1e-50FFCP PHASE1:Hg19::chr20:61204240..61204241,+#_dee81e90f40530db1ed9a0623fc6aab6p@chr20:61204240..61204241, +
3.1e-50FFCP PHASE2:Hg19::chr13:104778247..104778293,+#_dee81e90f40530db1ed9a0623fc6aab6p@chr13:104778247..104778293, +
5.14e-50FFCP PHASE1:Hg19::chr14:37642016..37642022,-#_65af1568ee62506984b5d73e871a874ap7@SLC25A21
5.14e-50FFCP PHASE2:Hg19::chr14:37642016..37642022,-#_65af1568ee62506984b5d73e871a874ap7@SLC25A21
5.14e-50FFCP PHASE2:Hg19::chr21:44592820..44592840,-#_65af1568ee62506984b5d73e871a874ap2@CU686889
5.14e-50FFCP PHASE1:Hg19::chr21:44592820..44592840,-#_65af1568ee62506984b5d73e871a874ap2@CU686889
6.6e-50FFCP PHASE1:Hg19::chr21:44589339..44589372,-#_b46a5896e0ed110a955a939cc7be1c62p@chr21:44589339..44589372, -
6.6e-50FFCP PHASE1:Hg19::chr12:132475501..132475504,+#_b46a5896e0ed110a955a939cc7be1c62p@chr12:132475501..132475504, +
6.6e-50FFCP PHASE2:Hg19::chr12:132475501..132475504,+#_b46a5896e0ed110a955a939cc7be1c62p@chr12:132475501..132475504, +
6.6e-50FFCP PHASE2:Hg19::chr21:44592842..44592867,-#_b46a5896e0ed110a955a939cc7be1c62p1@CU686889
6.6e-50FFCP PHASE1:Hg19::chr21:44592842..44592867,-#_b46a5896e0ed110a955a939cc7be1c62p1@CU686889
6.6e-50FFCP PHASE2:Hg19::chr21:44589339..44589372,-#_b46a5896e0ed110a955a939cc7be1c62p@chr21:44589339..44589372, -
6.27e-44FFCP PHASE1:Hg19::chr11:31827535..31827565,-#_c4ea1b4ef3326fb2ef8dff404a5f2562p11@PAX6
6.27e-44FFCP PHASE2:Hg19::chr11:31827535..31827565,-#_c4ea1b4ef3326fb2ef8dff404a5f2562p11@PAX6
1.92e-41FFCP PHASE2:Hg19::chr3:186262166..186262170,-#_b475215bfe18fa114d531afe7820c39fp1@CRYGS
1.92e-41FFCP PHASE1:Hg19::chr3:186262166..186262170,-#_b475215bfe18fa114d531afe7820c39fp1@CRYGS
4.94e-40FFCP PHASE2:Hg19::chr5:112173525..112173532,+#_458ce48b64dc278dc5d9c7039687f339p@chr5:112173525..112173532, +
4.94e-40FFCP PHASE1:Hg19::chr5:112173525..112173532,+#_458ce48b64dc278dc5d9c7039687f339p@chr5:112173525..112173532, +
1.62e-37FFCP PHASE2:Hg19::chr1:29586692..29586705,+#_6fd334359ce64fd3239ffd32fb52ec2ep7@PTPRU
1.62e-37FFCP PHASE1:Hg19::chr1:29586692..29586705,+#_6fd334359ce64fd3239ffd32fb52ec2ep7@PTPRU
2.1e-35FFCP PHASE1:Hg19::chr14:60975644..60975673,+#_8d2d9d0fff1e94f40b4f115b71af538dp3@SIX6
2.1e-35FFCP PHASE2:Hg19::chr14:60975644..60975673,+#_8d2d9d0fff1e94f40b4f115b71af538dp3@SIX6
6.73e-35FFCP PHASE1:Hg19::chr14:60975871..60975880,+#_5229ea95770d2ba7bafa739e29f783bep4@SIX6
6.73e-35FFCP PHASE2:Hg19::chr14:60975871..60975880,+#_5229ea95770d2ba7bafa739e29f783bep4@SIX6
5.06e-34FFCP PHASE1:Hg19::chr11:31667372..31667383,-#_c056f9e5eabc87024614814e5b107b2cp@chr11:31667372..31667383, -
5.06e-34FFCP PHASE2:Hg19::chr11:31667372..31667383,-#_c056f9e5eabc87024614814e5b107b2cp@chr11:31667372..31667383, -
8.36e-34FFCP PHASE2:Hg19::chr19:1470631..1470648,-#_db08d0d05268d043378a7fb4e8f49ff2p@chr19:1470631..1470648, -
8.36e-34FFCP PHASE1:Hg19::chr19:1470631..1470648,-#_db08d0d05268d043378a7fb4e8f49ff2p@chr19:1470631..1470648, -
5.55e-33FFCP PHASE2:Hg19::chr21:44589135..44589151,+#_6b068f9bb41501225c422f75cdac3980p1@CRYAA
5.55e-33FFCP PHASE1:Hg19::chr21:44589135..44589151,+#_6b068f9bb41501225c422f75cdac3980p1@CRYAA
9.55e-33FFCP PHASE1:Hg19::chr17:27573875..27573878,+#_1b071f8024fdc5bd8f8ed6a2fb3591bcp1@CRYBA1
9.55e-33FFCP PHASE2:Hg19::chr17:27573875..27573878,+#_1b071f8024fdc5bd8f8ed6a2fb3591bcp1@CRYBA1
2.74e-29FFCP PHASE2:Hg19::chr2:45168589..45168601,-#_a3db05f17656888530c071fce9cfa70dp2@ENST00000456467
2.74e-29FFCP PHASE1:Hg19::chr2:45168589..45168601,-#_a3db05f17656888530c071fce9cfa70dp2@ENST00000456467
3.65e-29FFCP PHASE2:Hg19::chr7:107883678..107883689,-#_ff1c9c97999dcfc827ce5aa14d4b9027p13@NRCAM
3.65e-29FFCP PHASE1:Hg19::chr7:107883678..107883689,-#_ff1c9c97999dcfc827ce5aa14d4b9027p13@NRCAM
7.46e-29FFCP PHASE1:Hg19::chr13:114202163..114202178,+#_21d133cb35ee34efde993c98d7aee3fap@chr13:114202163..114202178, +
7.46e-29FFCP PHASE2:Hg19::chr13:114202163..114202178,+#_21d133cb35ee34efde993c98d7aee3fap@chr13:114202163..114202178, +
1.36e-28FFCP PHASE2:Hg19::chr3:173116225..173116242,+#_50c83c05213f66ef129e47ec9de0ba97p10@NLGN1
1.36e-28FFCP PHASE1:Hg19::chr3:173116225..173116242,+#_50c83c05213f66ef129e47ec9de0ba97p10@NLGN1
2.64e-27FFCP PHASE2:Hg19::chr2:45169233..45169244,+#_96e7c13256e91368eb1e6dda81ece19ep10@SIX3
2.64e-27FFCP PHASE1:Hg19::chr2:45169233..45169244,+#_96e7c13256e91368eb1e6dda81ece19ep10@SIX3
8.39e-27FFCP PHASE1:Hg19::chr14:60975858..60975869,+#_df31c956872a434e82f1ab3ce0450414p2@SIX6
8.39e-27FFCP PHASE2:Hg19::chr14:60975858..60975869,+#_df31c956872a434e82f1ab3ce0450414p2@SIX6
5.56e-26FFCP PHASE2:Hg19::chr20:35861148..35861151,+#_aace773b701378e4a9f2e983c30fa86bp@chr20:35861148..35861151, +
5.56e-26FFCP PHASE1:Hg19::chr20:35861148..35861151,+#_aace773b701378e4a9f2e983c30fa86bp@chr20:35861148..35861151, +
5.56e-26FFCP PHASE1:Hg19::chr1:147374915..147374932,+#_aace773b701378e4a9f2e983c30fa86bp1@GJA8
5.56e-26FFCP PHASE2:Hg19::chrX:43587410..43587413,+#_aace773b701378e4a9f2e983c30fa86bp@chrX:43587410..43587413, +
5.56e-26FFCP PHASE1:Hg19::chrX:43587410..43587413,+#_aace773b701378e4a9f2e983c30fa86bp@chrX:43587410..43587413, +
5.56e-26FFCP PHASE2:Hg19::chr19:40920692..40920700,-#_aace773b701378e4a9f2e983c30fa86bp@chr19:40920692..40920700, -
5.56e-26FFCP PHASE2:Hg19::chr3:150690809..150690822,-#_aace773b701378e4a9f2e983c30fa86bp3@CLRN1
5.56e-26FFCP PHASE1:Hg19::chr3:150690809..150690822,-#_aace773b701378e4a9f2e983c30fa86bp3@CLRN1
5.56e-26FFCP PHASE1:Hg19::chr19:40920692..40920700,-#_aace773b701378e4a9f2e983c30fa86bp@chr19:40920692..40920700, -
5.56e-26FFCP PHASE2:Hg19::chr9:75848662..75848671,-#_aace773b701378e4a9f2e983c30fa86bp@chr9:75848662..75848671, -
5.56e-26FFCP PHASE1:Hg19::chr9:75848662..75848671,-#_aace773b701378e4a9f2e983c30fa86bp@chr9:75848662..75848671, -
5.56e-26FFCP PHASE2:Hg19::chr1:147374915..147374932,+#_aace773b701378e4a9f2e983c30fa86bp1@GJA8
7.14e-26FFCP PHASE2:Hg19::chr21:44592750..44592758,-#_fbc5f34e34bd779997da02baaac84af4p4@CU686889
7.14e-26FFCP PHASE1:Hg19::chr19:41727698..41727705,+#_fbc5f34e34bd779997da02baaac84af4p@chr19:41727698..41727705, +
7.14e-26FFCP PHASE2:Hg19::chr2:45154282..45154288,-#_fbc5f34e34bd779997da02baaac84af4p@chr2:45154282..45154288, -
7.14e-26FFCP PHASE2:Hg19::chr5:124468141..124468176,-#_fbc5f34e34bd779997da02baaac84af4p@chr5:124468141..124468176, -
7.14e-26FFCP PHASE2:Hg19::chr5:45038620..45038622,+#_fbc5f34e34bd779997da02baaac84af4p@chr5:45038620..45038622, +
7.14e-26FFCP PHASE1:Hg19::chr2:45154282..45154288,-#_fbc5f34e34bd779997da02baaac84af4p@chr2:45154282..45154288, -
7.14e-26FFCP PHASE2:Hg19::chr1:45769711..45769721,-#_fbc5f34e34bd779997da02baaac84af4p@chr1:45769711..45769721, -
7.14e-26FFCP PHASE1:Hg19::chr21:44592750..44592758,-#_fbc5f34e34bd779997da02baaac84af4p4@CU686889
7.14e-26FFCP PHASE1:Hg19::chr13:72440726..72440736,-#_fbc5f34e34bd779997da02baaac84af4p19@DACH1
7.14e-26FFCP PHASE1:Hg19::chr5:124468141..124468176,-#_fbc5f34e34bd779997da02baaac84af4p@chr5:124468141..124468176, -
7.14e-26FFCP PHASE1:Hg19::chr1:45769711..45769721,-#_fbc5f34e34bd779997da02baaac84af4p@chr1:45769711..45769721, -
7.14e-26FFCP PHASE2:Hg19::chr21:44592358..44592365,+#_fbc5f34e34bd779997da02baaac84af4p@chr21:44592358..44592365, +
7.14e-26FFCP PHASE2:Hg19::chr20:33903184..33903189,-#_fbc5f34e34bd779997da02baaac84af4p11@UQCC
7.14e-26FFCP PHASE1:Hg19::chr5:45038620..45038622,+#_fbc5f34e34bd779997da02baaac84af4p@chr5:45038620..45038622, +
7.14e-26FFCP PHASE1:Hg19::chr19:17137781..17137792,-#_fbc5f34e34bd779997da02baaac84af4p6@CPAMD8
7.14e-26FFCP PHASE1:Hg19::chr20:33903184..33903189,-#_fbc5f34e34bd779997da02baaac84af4p11@UQCC
7.14e-26FFCP PHASE1:Hg19::chr21:44592358..44592365,+#_fbc5f34e34bd779997da02baaac84af4p@chr21:44592358..44592365, +
7.14e-26FFCP PHASE2:Hg19::chr13:72440726..72440736,-#_fbc5f34e34bd779997da02baaac84af4p19@DACH1
7.14e-26FFCP PHASE2:Hg19::chr21:44592788..44592807,+#_fbc5f34e34bd779997da02baaac84af4p@chr21:44592788..44592807, +
7.14e-26FFCP PHASE2:Hg19::chr2:693025..693036,+#_fbc5f34e34bd779997da02baaac84af4p@chr2:693025..693036, +
7.14e-26FFCP PHASE2:Hg19::chr1:86064794..86064797,+#_fbc5f34e34bd779997da02baaac84af4p1@ENST00000426794
7.14e-26FFCP PHASE2:Hg19::chr8:94870047..94870056,+#_fbc5f34e34bd779997da02baaac84af4p30@PDP1
7.14e-26FFCP PHASE2:Hg19::chr1:115873480..115873484,+#_fbc5f34e34bd779997da02baaac84af4p@chr1:115873480..115873484, +
7.14e-26FFCP PHASE1:Hg19::chr8:94870047..94870056,+#_fbc5f34e34bd779997da02baaac84af4p30@PDP1
7.14e-26FFCP PHASE2:Hg19::chr5:464155..464205,+#_fbc5f34e34bd779997da02baaac84af4p@chr5:464155..464205, +
7.14e-26FFCP PHASE2:Hg19::chr2:10538258..10538282,+#_fbc5f34e34bd779997da02baaac84af4p@chr2:10538258..10538282, +
7.14e-26FFCP PHASE1:Hg19::chr21:44592788..44592807,+#_fbc5f34e34bd779997da02baaac84af4p@chr21:44592788..44592807, +
7.14e-26FFCP PHASE1:Hg19::chr1:86064794..86064797,+#_fbc5f34e34bd779997da02baaac84af4p1@ENST00000426794
7.14e-26FFCP PHASE1:Hg19::chr2:693025..693036,+#_fbc5f34e34bd779997da02baaac84af4p@chr2:693025..693036, +
7.14e-26FFCP PHASE1:Hg19::chr2:10538258..10538282,+#_fbc5f34e34bd779997da02baaac84af4p@chr2:10538258..10538282, +
7.14e-26FFCP PHASE1:Hg19::chr10:73406056..73406065,+#_fbc5f34e34bd779997da02baaac84af4p@chr10:73406056..73406065, +
7.14e-26FFCP PHASE1:Hg19::chr5:464155..464205,+#_fbc5f34e34bd779997da02baaac84af4p@chr5:464155..464205, +
7.14e-26FFCP PHASE2:Hg19::chr10:73406056..73406065,+#_fbc5f34e34bd779997da02baaac84af4p@chr10:73406056..73406065, +
7.14e-26FFCP PHASE1:Hg19::chr1:115873480..115873484,+#_fbc5f34e34bd779997da02baaac84af4p@chr1:115873480..115873484, +