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Novel motif:105

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name:motif105_KTNGNAGWMG

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0030277 maintenance of gastrointestinal epithelium 1.083031e-14
GO:0006434 seryl-tRNA aminoacylation 1.187150e-14
GO:0010669 epithelial structure maintenance 8.553148e-13
GO:0071173 spindle assembly checkpoint 5.308361e-11
GO:0031577 spindle checkpoint 5.430510e-11
GO:0007094 mitotic cell cycle spindle assembly checkpoint 7.865045e-11
GO:0071174 mitotic cell cycle spindle checkpoint 1.457188e-10
GO:0045841 negative regulation of mitotic metaphase/anaphase transition 2.936678e-10
GO:0030071 regulation of mitotic metaphase/anaphase transition 3.753665e-9
GO:0042475 odontogenesis of dentine-containing tooth 4.569977e-8
GO:0006569 tryptophan catabolic process 5.224296e-8
GO:0016056 rhodopsin mediated signaling pathway 5.966048e-8
GO:0045839 negative regulation of mitosis 6.566858e-8
GO:0006568 tryptophan metabolic process 6.604327e-8
GO:0032534 regulation of microvillus assembly 6.605532e-8
GO:0016032 viral reproduction 7.538022e-8
GO:0048378 regulation of lateral mesodermal cell fate specification 8.325508e-8
GO:0048075 positive regulation of eye pigmentation 1.269605e-7
GO:0061077 chaperone-mediated protein folding 1.386243e-7
GO:0033634 positive regulation of cell-cell adhesion mediated by integrin 3.422905e-7
GO:0009586 rhodopsin mediated phototransduction 5.748707e-7
GO:0006767 water-soluble vitamin metabolic process 6.348196e-7
GO:0010569 regulation of double-strand break repair via homologous recombination 6.463210e-7
GO:0071338 positive regulation of hair follicle cell proliferation 9.154344e-7
GO:0048073 regulation of eye pigmentation 1.652175e-6
GO:0006369 termination of RNA polymerase II transcription 1.906713e-6
GO:0032530 regulation of microvillus organization 2.094396e-6
GO:0007040 lysosome organization 2.878310e-6
GO:0022600 digestive system process 2.999190e-6
GO:0070189 kynurenine metabolic process 3.288745e-6
GO:0008582 regulation of synaptic growth at neuromuscular junction 3.808069e-6
GO:0002502 peptide antigen assembly with MHC class I protein complex 3.875621e-6
GO:0060789 hair follicle placode formation 3.878568e-6
GO:0006403 RNA localization 4.192861e-6
GO:0070389 chaperone cofactor-dependent protein refolding 4.509887e-6
GO:0043206 fibril organization 4.712392e-6
GO:0006457 protein folding 4.771998e-6
GO:2000119 negative regulation of sodium-dependent phosphate transport 7.059253e-6
GO:0051028 mRNA transport 7.067496e-6
GO:0009074 aromatic amino acid family catabolic process 7.117668e-6
GO:0035621 ER to Golgi ceramide transport 7.196793e-6
GO:0048352 paraxial mesoderm structural organization 8.110212e-6
GO:0021998 neural plate mediolateral regionalization 8.110212e-6
GO:0051534 negative regulation of NFAT protein import into nucleus 8.842522e-6
GO:0031214 biomineral tissue development 8.905649e-6
GO:0060788 ectodermal placode formation 9.113964e-6
GO:0034660 ncRNA metabolic process 9.156779e-6
GO:0006552 leucine catabolic process 9.185715e-6
GO:0007586 digestion 9.514260e-6
GO:0019439 aromatic compound catabolic process 1.022608e-5
GO:0040032 post-embryonic body morphogenesis 1.103431e-5
GO:0070584 mitochondrion morphogenesis 1.116661e-5
GO:0070831 basement membrane assembly 1.177286e-5
GO:0007603 phototransduction, visible light 1.194155e-5
GO:0018208 peptidyl-proline modification 1.435461e-5
GO:0035088 establishment or maintenance of apical/basal cell polarity 1.591339e-5
GO:0071816 tail-anchored membrane protein insertion into ER membrane 1.686066e-5
GO:0050821 protein stabilization 1.787845e-5
GO:0007033 vacuole organization 1.869223e-5
GO:0000966 RNA 5'-end processing 1.884377e-5
GO:0048382 mesendoderm development 2.107356e-5
GO:0006551 leucine metabolic process 2.385536e-5
GO:0051168 nuclear export 2.803129e-5
GO:0006259 DNA metabolic process 3.379767e-5
GO:0051988 regulation of attachment of spindle microtubules to kinetochore 3.555885e-5
GO:0021798 forebrain dorsal/ventral pattern formation 3.764020e-5
GO:0019441 tryptophan catabolic process to kynurenine 3.767927e-5
GO:0050658 RNA transport 3.926287e-5
GO:0065004 protein-DNA complex assembly 3.966087e-5
GO:0031647 regulation of protein stability 4.023859e-5
GO:0051325 interphase 4.496093e-5
GO:0042535 positive regulation of tumor necrosis factor biosynthetic process 4.772906e-5
GO:0009159 deoxyribonucleoside monophosphate catabolic process 4.784100e-5
GO:0016598 protein arginylation 4.784100e-5
GO:0021854 hypothalamus development 4.973412e-5
GO:0060839 endothelial cell fate commitment 5.015595e-5
GO:0009956 radial pattern formation 5.074748e-5
GO:0034508 centromere complex assembly 5.688145e-5
GO:0006406 mRNA export from nucleus 5.890852e-5
GO:0009108 coenzyme biosynthetic process 6.073549e-5
GO:0000725 recombinational repair 6.217175e-5
GO:0030198 extracellular matrix organization 6.715626e-5
GO:0034445 negative regulation of plasma lipoprotein particle oxidation 7.325839e-5
GO:0060350 endochondral bone morphogenesis 7.569724e-5
GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment 7.693908e-5
GO:0006974 response to DNA damage stimulus 8.199173e-5
GO:0046907 intracellular transport 8.397453e-5
GO:0000724 double-strand break repair via homologous recombination 8.470975e-5
GO:0006586 indolalkylamine metabolic process 8.818017e-5
GO:0006096 glycolysis 8.907030e-5
GO:0002063 chondrocyte development 9.085484e-5
GO:0032964 collagen biosynthetic process 9.879806e-5
GO:0042538 hyperosmotic salinity response 9.974227e-5
GO:0021759 globus pallidus development 1.026435e-4
GO:0051188 cofactor biosynthetic process 1.125420e-4
GO:0010966 regulation of phosphate transport 1.182738e-4
GO:0042402 cellular biogenic amine catabolic process 1.219321e-4
GO:0001894 tissue homeostasis 1.294911e-4
GO:0051329 interphase of mitotic cell cycle 1.315800e-4
GO:0035308 negative regulation of protein dephosphorylation 1.372494e-4
GO:0009072 aromatic amino acid family metabolic process 1.414542e-4
GO:0044236 multicellular organismal metabolic process 1.486423e-4
GO:0035305 negative regulation of dephosphorylation 1.504373e-4
GO:0006744 ubiquinone biosynthetic process 1.623602e-4
GO:0042696 menarche 1.695106e-4
GO:0031497 chromatin assembly 1.744789e-4
GO:0050908 detection of light stimulus involved in visual perception 1.782770e-4
GO:0000075 cell cycle checkpoint 1.844882e-4
GO:0034442 regulation of lipoprotein oxidation 1.906090e-4
GO:0010948 negative regulation of cell cycle process 1.959826e-4
GO:0070925 organelle assembly 2.028665e-4
GO:0007191 activation of adenylate cyclase activity by dopamine receptor signaling pathway 2.186248e-4
GO:0032298 positive regulation of DNA-dependent DNA replication initiation 2.237762e-4
GO:0030683 evasion by virus of host immune response 2.237762e-4
GO:0006272 leading strand elongation 2.237762e-4
GO:0007093 mitotic cell cycle checkpoint 2.251097e-4
GO:0033693 neurofilament bundle assembly 2.338011e-4
GO:0009303 rRNA transcription 2.358436e-4
GO:0015931 nucleobase-containing compound transport 2.490998e-4
GO:0006171 cAMP biosynthetic process 2.502033e-4
GO:0048339 paraxial mesoderm development 2.516006e-4
GO:0045426 quinone cofactor biosynthetic process 2.528446e-4
GO:0022601 menstrual cycle phase 2.586263e-4
GO:0030388 fructose 1,6-bisphosphate metabolic process 2.642746e-4
GO:0006418 tRNA aminoacylation for protein translation 2.662188e-4
GO:0043039 tRNA aminoacylation 2.726617e-4
GO:0035089 establishment of apical/basal cell polarity 2.796022e-4
GO:0006768 biotin metabolic process 2.802783e-4
GO:0009107 lipoate biosynthetic process 2.869931e-4
GO:0050690 regulation of defense response to virus by virus 2.959515e-4
GO:0030199 collagen fibril organization 3.002309e-4
GO:0071824 protein-DNA complex subunit organization 3.016529e-4
GO:0035545 determination of left/right asymmetry in nervous system 3.033965e-4
GO:0031124 mRNA 3'-end processing 3.066321e-4
GO:0051004 regulation of lipoprotein lipase activity 3.144278e-4
GO:0043503 skeletal muscle fiber adaptation 3.204724e-4
GO:0044205 'de novo' UMP biosynthetic process 3.226370e-4
GO:0006334 nucleosome assembly 3.539524e-4
GO:0042661 regulation of mesodermal cell fate specification 3.547005e-4
GO:0045116 protein neddylation 3.612208e-4
GO:0006405 RNA export from nucleus 3.699914e-4
GO:0060850 regulation of transcription involved in cell fate commitment 3.828816e-4
GO:0031060 regulation of histone methylation 3.932715e-4
GO:0015758 glucose transport 4.010256e-4
GO:0034509 centromeric core chromatin assembly 4.133684e-4
GO:0042375 quinone cofactor metabolic process 4.279791e-4
GO:0006310 DNA recombination 4.492907e-4
GO:0042770 signal transduction in response to DNA damage 4.543370e-4
GO:0007215 glutamate signaling pathway 4.559691e-4
GO:0019363 pyridine nucleotide biosynthetic process 4.654452e-4
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway 4.663752e-4
GO:0002897 positive regulation of central B cell tolerance induction 4.737669e-4
GO:0002508 central tolerance induction 4.737669e-4
GO:0070375 BMK cascade 4.737877e-4
GO:0008645 hexose transport 4.909314e-4
GO:0051930 regulation of sensory perception of pain 4.949437e-4
GO:0021520 spinal cord motor neuron cell fate specification 5.298053e-4
GO:0015749 monosaccharide transport 5.424070e-4
GO:0032637 interleukin-8 production 5.550652e-4
GO:0022403 cell cycle phase 5.671566e-4
GO:0019511 peptidyl-proline hydroxylation 5.726575e-4
GO:0071156 regulation of cell cycle arrest 5.728675e-4
GO:2000380 regulation of mesoderm development 5.822434e-4
GO:0006323 DNA packaging 5.911451e-4
GO:0043691 reverse cholesterol transport 5.959113e-4
GO:0051017 actin filament bundle assembly 6.015652e-4
GO:0010596 negative regulation of endothelial cell migration 6.023926e-4
GO:0032463 negative regulation of protein homooligomerization 6.094073e-4
GO:0000086 G2/M transition of mitotic cell cycle 6.221630e-4
GO:0051788 response to misfolded protein 6.230307e-4
GO:2000779 regulation of double-strand break repair 6.242136e-4
GO:0060836 lymphatic endothelial cell differentiation 6.356608e-4
GO:0019805 quinolinate biosynthetic process 6.372090e-4
GO:0001831 trophectodermal cellular morphogenesis 6.462738e-4
GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway 6.567541e-4
GO:2000143 negative regulation of transcription initiation, DNA-dependent 6.641455e-4
GO:2000627 positive regulation of miRNA catabolic process 6.641455e-4
GO:0071042 nuclear polyadenylation-dependent mRNA catabolic process 6.641455e-4
GO:0000964 mitochondrial RNA 5'-end processing 6.641455e-4
GO:0000416 positive regulation of histone H3-K36 methylation 6.641455e-4
GO:0032963 collagen metabolic process 6.741872e-4
GO:0007029 endoplasmic reticulum organization 6.801966e-4
GO:0007017 microtubule-based process 6.853250e-4
GO:0061157 mRNA destabilization 7.102910e-4
GO:0010609 posttranscriptional regulation of gene expression by mRNA localization 7.102910e-4
GO:0046874 quinolinate metabolic process 7.488774e-4
GO:0044259 multicellular organismal macromolecule metabolic process 7.496770e-4
GO:0051177 meiotic sister chromatid cohesion 7.577918e-4
GO:0009304 tRNA transcription 7.633050e-4
GO:0051382 kinetochore assembly 7.685412e-4
GO:0006769 nicotinamide metabolic process 8.356790e-4
GO:0007530 sex determination 8.786920e-4
GO:0000413 protein peptidyl-prolyl isomerization 8.819155e-4
GO:0021771 lateral geniculate nucleus development 8.966864e-4
GO:0034377 plasma lipoprotein particle assembly 9.464510e-4
GO:0034728 nucleosome organization 9.595459e-4
GO:0060351 cartilage development involved in endochondral bone morphogenesis 9.637031e-4
GO:0043603 cellular amide metabolic process 1.014971e-3
GO:0061011 hepatic duct development 1.028705e-3
GO:0021586 pons maturation 1.028705e-3
GO:0072148 epithelial cell fate commitment 1.048755e-3
GO:0042048 olfactory behavior 1.071244e-3
GO:0051893 regulation of focal adhesion assembly 1.108487e-3
GO:0021877 forebrain neuron fate commitment 1.195687e-3
GO:0042274 ribosomal small subunit biogenesis 1.222589e-3
GO:0070972 protein localization in endoplasmic reticulum 1.252727e-3
GO:0070727 cellular macromolecule localization 1.265523e-3
GO:0060249 anatomical structure homeostasis 1.265988e-3
GO:0019047 provirus integration 1.267560e-3
GO:0031398 positive regulation of protein ubiquitination 1.271580e-3
GO:0009584 detection of visible light 1.276810e-3
GO:0042534 regulation of tumor necrosis factor biosynthetic process 1.282264e-3
GO:0006000 fructose metabolic process 1.331726e-3
GO:0018027 peptidyl-lysine dimethylation 1.348559e-3
GO:0015031 protein transport 1.376175e-3
GO:0009435 NAD biosynthetic process 1.386763e-3
GO:0051383 kinetochore organization 1.388297e-3
GO:0045786 negative regulation of cell cycle 1.407431e-3
GO:0000414 regulation of histone H3-K36 methylation 1.454910e-3
GO:0051649 establishment of localization in cell 1.479501e-3
GO:0009642 response to light intensity 1.483620e-3
GO:0000090 mitotic anaphase 1.485093e-3
GO:0060059 embryonic retina morphogenesis in camera-type eye 1.498325e-3
GO:0043049 otic placode formation 1.528226e-3
GO:0022417 protein maturation by protein folding 1.595492e-3
GO:0001880 Mullerian duct regression 1.617972e-3
GO:0045184 establishment of protein localization 1.622285e-3
GO:0071827 plasma lipoprotein particle organization 1.656777e-3
GO:0060033 anatomical structure regression 1.657106e-3
GO:0007173 epidermal growth factor receptor signaling pathway 1.657783e-3
GO:0042254 ribosome biogenesis 1.666851e-3
GO:0006710 androgen catabolic process 1.687376e-3
GO:0060897 neural plate regionalization 1.700159e-3
GO:0031123 RNA 3'-end processing 1.729375e-3
GO:0021872 forebrain generation of neurons 1.757082e-3
GO:0048664 neuron fate determination 1.769028e-3
GO:0031627 telomeric loop formation 1.773988e-3
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1.773988e-3
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1.773988e-3
GO:0034613 cellular protein localization 1.816807e-3
GO:0010812 negative regulation of cell-substrate adhesion 1.819171e-3
GO:2000124 regulation of endocannabinoid signaling pathway 1.827633e-3
GO:0033007 negative regulation of mast cell activation involved in immune response 1.830910e-3
GO:0014829 vascular smooth muscle contraction 1.831781e-3
GO:0033632 regulation of cell-cell adhesion mediated by integrin 1.847975e-3
GO:0006260 DNA replication 1.866473e-3
GO:0003203 endocardial cushion morphogenesis 1.897608e-3
GO:0032467 positive regulation of cytokinesis 1.897608e-3
GO:0006007 glucose catabolic process 1.942484e-3
GO:0032241 positive regulation of nucleobase-containing compound transport 1.981217e-3
GO:0070192 chromosome organization involved in meiosis 2.036657e-3
GO:0035304 regulation of protein dephosphorylation 2.044330e-3
GO:0030916 otic vesicle formation 2.084522e-3
GO:0002092 positive regulation of receptor internalization 2.086943e-3
GO:0001937 negative regulation of endothelial cell proliferation 2.090152e-3
GO:0008054 cyclin catabolic process 2.145928e-3
GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase 2.182997e-3
GO:0035694 mitochondrial protein catabolic process 2.306349e-3
GO:0032515 negative regulation of phosphoprotein phosphatase activity 2.321444e-3
GO:0072334 UDP-galactose transmembrane transport 2.358459e-3
GO:0072302 negative regulation of metanephric glomerular mesangial cell proliferation 2.358459e-3
GO:0061032 visceral serous pericardium development 2.358459e-3
GO:0035137 hindlimb morphogenesis 2.427449e-3
GO:0007224 smoothened signaling pathway 2.431220e-3
GO:0000730 DNA recombinase assembly 2.522209e-3
GO:0001787 natural killer cell proliferation 2.590983e-3
GO:0060044 negative regulation of cardiac muscle cell proliferation 2.640268e-3
GO:0051225 spindle assembly 2.642402e-3
GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration 2.653238e-3
GO:0008355 olfactory learning 2.653238e-3
GO:0019359 nicotinamide nucleotide biosynthetic process 2.653328e-3
GO:0030865 cortical cytoskeleton organization 2.756938e-3
GO:0071103 DNA conformation change 2.816406e-3
GO:0007194 negative regulation of adenylate cyclase activity 2.833275e-3
GO:0072301 regulation of metanephric glomerular mesangial cell proliferation 2.837158e-3
GO:0048702 embryonic neurocranium morphogenesis 2.837158e-3
GO:0043310 negative regulation of eosinophil degranulation 2.858256e-3
GO:2000409 positive regulation of T cell extravasation 2.858256e-3
GO:0051106 positive regulation of DNA ligation 2.858256e-3
GO:0035705 T-helper 17 cell chemotaxis 2.858256e-3
GO:0035696 monocyte extravasation 2.858256e-3
GO:0015891 siderophore transport 2.909718e-3
GO:0071850 mitotic cell cycle arrest 2.911456e-3
GO:0060123 regulation of growth hormone secretion 2.912782e-3
GO:0051532 regulation of NFAT protein import into nucleus 2.933920e-3
GO:0000216 M/G1 transition of mitotic cell cycle 2.940549e-3
GO:0006342 chromatin silencing 2.983344e-3
GO:0006959 humoral immune response 3.006060e-3
GO:0008629 induction of apoptosis by intracellular signals 3.022479e-3
GO:0042026 protein refolding 3.042244e-3
GO:0048668 collateral sprouting 3.182120e-3
GO:0051641 cellular localization 3.215151e-3
GO:0009190 cyclic nucleotide biosynthetic process 3.259257e-3
GO:0012502 induction of programmed cell death 3.267962e-3
GO:0043633 polyadenylation-dependent RNA catabolic process 3.286429e-3
GO:0000965 mitochondrial RNA 3'-end processing 3.286429e-3
GO:0000962 positive regulation of mitochondrial RNA catabolic process 3.286429e-3
GO:0000958 mitochondrial mRNA catabolic process 3.286429e-3
GO:0051208 sequestering of calcium ion 3.364240e-3
GO:0061072 iris morphogenesis 3.411062e-3
GO:0006766 vitamin metabolic process 3.412811e-3
GO:0002380 immunoglobulin secretion involved in immune response 3.482537e-3
GO:0002635 negative regulation of germinal center formation 3.482537e-3
GO:0051350 negative regulation of lyase activity 3.491889e-3
GO:0090129 positive regulation of synapse maturation 3.535529e-3
GO:0008089 anterograde axon cargo transport 3.535529e-3
GO:0003272 endocardial cushion formation 3.535529e-3
GO:0006911 phagocytosis, engulfment 3.628998e-3
GO:0090174 organelle membrane fusion 3.722484e-3
GO:0015684 ferrous iron transport 3.722484e-3
GO:0009162 deoxyribonucleoside monophosphate metabolic process 3.722484e-3
GO:0045740 positive regulation of DNA replication 3.736657e-3
GO:0007088 regulation of mitosis 3.745981e-3
GO:0071896 protein localization to adherens junction 3.861522e-3
GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine 3.861522e-3
GO:0008104 protein localization 3.863086e-3
GO:0015780 nucleotide-sugar transport 3.884492e-3
GO:0060486 Clara cell differentiation 3.897926e-3
GO:0048263 determination of dorsal identity 3.949184e-3
GO:0022002 negative regulation of anterior neural cell fate commitment of the neural plate by Wnt receptor signaling pathway 3.949184e-3
GO:0034622 cellular macromolecular complex assembly 3.997809e-3
GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis 4.000306e-3
GO:0006917 induction of apoptosis 4.001692e-3
GO:0033081 regulation of T cell differentiation in thymus 4.148208e-3
GO:0032854 positive regulation of Rap GTPase activity 4.173134e-3
GO:0001935 endothelial cell proliferation 4.177960e-3
GO:0042921 glucocorticoid receptor signaling pathway 4.260722e-3
GO:0007130 synaptonemal complex assembly 4.261305e-3
GO:0042074 cell migration involved in gastrulation 4.290938e-3
GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway 4.335910e-3
GO:0018026 peptidyl-lysine monomethylation 4.367898e-3
GO:0015918 sterol transport 4.480098e-3
GO:0008630 DNA damage response, signal transduction resulting in induction of apoptosis 4.535345e-3
GO:0030330 DNA damage response, signal transduction by p53 class mediator 4.583760e-3
GO:0006477 protein sulfation 4.623183e-3
GO:0031279 regulation of cyclase activity 4.838216e-3
GO:0034379 very-low-density lipoprotein particle assembly 4.934622e-3
GO:0043149 stress fiber assembly 5.313590e-3
GO:0007126 meiosis 5.315264e-3
GO:0044070 regulation of anion transport 5.319867e-3
GO:0032594 protein transport within lipid bilayer 5.400464e-3
GO:0007283 spermatogenesis 5.437838e-3
GO:0071777 positive regulation of cell cycle cytokinesis 5.513988e-3
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 5.538586e-3
GO:0009794 regulation of mitotic cell cycle, embryonic 5.549503e-3
GO:0010608 posttranscriptional regulation of gene expression 5.675270e-3
GO:0040040 thermosensory behavior 5.712577e-3
GO:0070059 apoptosis in response to endoplasmic reticulum stress 5.753969e-3
GO:0016072 rRNA metabolic process 5.843403e-3
GO:0031062 positive regulation of histone methylation 5.869371e-3
GO:0019882 antigen processing and presentation 5.899619e-3
GO:0006733 oxidoreduction coenzyme metabolic process 5.993240e-3
GO:0030301 cholesterol transport 6.012407e-3
GO:0009886 post-embryonic morphogenesis 6.059891e-3
GO:0090128 regulation of synapse maturation 6.080246e-3
GO:0006353 transcription termination, DNA-dependent 6.141797e-3
GO:0001921 positive regulation of receptor recycling 6.172874e-3
GO:0072132 mesenchyme morphogenesis 6.176287e-3
GO:0070734 histone H3-K27 methylation 6.205932e-3
GO:0008334 histone mRNA metabolic process 6.263187e-3
GO:0035150 regulation of tube size 6.308329e-3
GO:0072331 signal transduction by p53 class mediator 6.375847e-3
GO:0051443 positive regulation of ubiquitin-protein ligase activity 6.398231e-3
GO:0034470 ncRNA processing 6.487768e-3
GO:0006892 post-Golgi vesicle-mediated transport 6.512258e-3
GO:0031128 developmental induction 6.568797e-3
GO:0019320 hexose catabolic process 6.607509e-3
GO:0022028 tangential migration from the subventricular zone to the olfactory bulb 6.610997e-3
GO:0045609 positive regulation of auditory receptor cell differentiation 6.632970e-3
GO:0043622 cortical microtubule organization 6.632970e-3
GO:0046833 positive regulation of RNA export from nucleus 6.632970e-3
GO:0030103 vasopressin secretion 6.632970e-3
GO:0042270 protection from natural killer cell mediated cytotoxicity 6.632970e-3
GO:0042667 auditory receptor cell fate specification 6.632970e-3
GO:0046365 monosaccharide catabolic process 6.643434e-3
GO:0007160 cell-matrix adhesion 6.678488e-3
GO:0071844 cellular component assembly at cellular level 6.720475e-3
GO:0035235 ionotropic glutamate receptor signaling pathway 6.733373e-3
GO:0018874 benzoate metabolic process 6.742678e-3
GO:0010950 positive regulation of endopeptidase activity 6.742678e-3
GO:0061017 hepatoblast differentiation 6.793089e-3
GO:0051571 positive regulation of histone H3-K4 methylation 6.835116e-3
GO:0001919 regulation of receptor recycling 6.896273e-3
GO:0046079 dUMP catabolic process 6.962720e-3
GO:0030225 macrophage differentiation 6.979098e-3
GO:0001958 endochondral ossification 7.042003e-3
GO:0031061 negative regulation of histone methylation 7.084431e-3
GO:0051322 anaphase 7.094648e-3
GO:0003420 regulation of growth plate cartilage chondrocyte proliferation 7.123465e-3
GO:0007602 phototransduction 7.135576e-3
GO:0006399 tRNA metabolic process 7.197596e-3
GO:0071157 negative regulation of cell cycle arrest 7.201271e-3
GO:0003197 endocardial cushion development 7.406351e-3
GO:0050880 regulation of blood vessel size 7.406558e-3
GO:0061136 regulation of proteasomal protein catabolic process 7.464476e-3
GO:0045761 regulation of adenylate cyclase activity 7.492930e-3
GO:0043497 regulation of protein heterodimerization activity 7.534760e-3
GO:0007097 nuclear migration 7.534760e-3
GO:0042476 odontogenesis 7.551778e-3
GO:0033036 macromolecule localization 7.660396e-3
GO:0000085 G2 phase of mitotic cell cycle 7.862821e-3
GO:0021521 ventral spinal cord interneuron specification 7.932275e-3
GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process 8.008724e-3
GO:0002541 activation of plasma proteins involved in acute inflammatory response 8.145835e-3
GO:0006268 DNA unwinding involved in replication 8.276555e-3
GO:0015986 ATP synthesis coupled proton transport 8.382823e-3
GO:0043525 positive regulation of neuron apoptosis 8.385775e-3
GO:0006269 DNA replication, synthesis of RNA primer 8.427865e-3
GO:0006913 nucleocytoplasmic transport 8.443421e-3
GO:0030502 negative regulation of bone mineralization 8.547113e-3
GO:0019896 axon transport of mitochondrion 8.591366e-3
GO:0051321 meiotic cell cycle 8.649812e-3
GO:0034621 cellular macromolecular complex subunit organization 8.749673e-3
GO:0031444 slow-twitch skeletal muscle fiber contraction 8.890794e-3
GO:0051983 regulation of chromosome segregation 9.149305e-3
GO:0021879 forebrain neuron differentiation 9.184921e-3
GO:0046210 nitric oxide catabolic process 9.368025e-3
GO:0090346 cellular organofluorine metabolic process 9.368025e-3
GO:0043602 nitrate catabolic process 9.368025e-3
GO:0042228 interleukin-8 biosynthetic process 9.368025e-3
GO:0001575 globoside metabolic process 9.368025e-3
GO:0035752 lysosomal lumen pH elevation 9.368025e-3
GO:0000046 autophagic vacuole fusion 9.368025e-3
GO:0022402 cell cycle process 9.465703e-3
GO:0060431 primary lung bud formation 9.466979e-3
GO:0060260 regulation of transcription initiation from RNA polymerase II promoter 9.526124e-3
GO:0045188 regulation of circadian sleep/wake cycle, non-REM sleep 9.557702e-3
GO:0051029 rRNA transport 9.765408e-3
GO:0021800 cerebral cortex tangential migration 9.765408e-3
GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process 9.898570e-3
GO:0097114 N-methyl-D-aspartate receptor clustering 1.004216e-2
GO:0097117 guanylate kinase-associated protein clustering 1.004216e-2
GO:0097112 gamma-aminobutyric acid receptor clustering 1.004216e-2
GO:0045110 intermediate filament bundle assembly 1.007210e-2
GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 1.010105e-2
GO:0051895 negative regulation of focal adhesion assembly 1.012896e-2
GO:0006270 DNA-dependent DNA replication initiation 1.015598e-2
GO:0008298 intracellular mRNA localization 1.022474e-2
GO:0030866 cortical actin cytoskeleton organization 1.039374e-2
GO:0010043 response to zinc ion 1.047798e-2
GO:0045047 protein targeting to ER 1.051935e-2
GO:0070979 protein K11-linked ubiquitination 1.054446e-2
GO:0045040 protein import into mitochondrial outer membrane 1.068765e-2
GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition 1.072164e-2
GO:0007402 ganglion mother cell fate determination 1.072164e-2
GO:0006428 isoleucyl-tRNA aminoacylation 1.072164e-2
GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation 1.072164e-2
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway 1.080060e-2
GO:0051169 nuclear transport 1.094165e-2
GO:0051339 regulation of lyase activity 1.094724e-2
GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity 1.100430e-2
GO:0042335 cuticle development 1.100430e-2
GO:0007141 male meiosis I 1.112820e-2
GO:0022415 viral reproductive process 1.116032e-2
GO:0006333 chromatin assembly or disassembly 1.128294e-2
GO:0006829 zinc ion transport 1.131997e-2
GO:0035928 rRNA import into mitochondrion 1.135058e-2
GO:0009106 lipoate metabolic process 1.142986e-2
GO:0048855 adenohypophysis morphogenesis 1.151224e-2
GO:0021933 radial glia guided migration of cerebellar granule cell 1.151224e-2
GO:0045070 positive regulation of viral genome replication 1.156354e-2
GO:0045650 negative regulation of macrophage differentiation 1.180430e-2
GO:0009620 response to fungus 1.192995e-2
GO:0070168 negative regulation of biomineral tissue development 1.200362e-2
GO:0035306 positive regulation of dephosphorylation 1.200362e-2
GO:0022617 extracellular matrix disassembly 1.209303e-2
GO:0046785 microtubule polymerization 1.215735e-2
GO:0030174 regulation of DNA-dependent DNA replication initiation 1.226705e-2
GO:0014826 vein smooth muscle contraction 1.247814e-2
GO:0035095 behavioral response to nicotine 1.252828e-2
GO:0048368 lateral mesoderm development 1.252831e-2
GO:0048669 collateral sprouting in absence of injury 1.273026e-2
GO:0060965 negative regulation of gene silencing by miRNA 1.274315e-2
GO:0046690 response to tellurium ion 1.274315e-2
GO:0009645 response to low light intensity stimulus 1.274315e-2
GO:0060684 epithelial-mesenchymal cell signaling 1.285902e-2
GO:0007192 activation of adenylate cyclase activity by serotonin receptor signaling pathway 1.293317e-2
GO:0060370 susceptibility to T cell mediated cytotoxicity 1.293317e-2
GO:0010923 negative regulation of phosphatase activity 1.319911e-2
GO:0031958 corticosteroid receptor signaling pathway 1.320780e-2
GO:0032695 negative regulation of interleukin-12 production 1.352737e-2
GO:0045793 positive regulation of cell size 1.353475e-2
GO:0006886 intracellular protein transport 1.359000e-2
GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter 1.378798e-2
GO:0010896 regulation of triglyceride catabolic process 1.379724e-2
GO:0019264 glycine biosynthetic process from serine 1.387835e-2
GO:0000921 septin ring assembly 1.387835e-2
GO:0051569 regulation of histone H3-K4 methylation 1.396566e-2
GO:0030032 lamellipodium assembly 1.408566e-2
GO:0045994 positive regulation of translational initiation by iron 1.411368e-2
GO:0002037 negative regulation of L-glutamate transport 1.411368e-2
GO:0048871 multicellular organismal homeostasis 1.416752e-2
GO:0007598 blood coagulation, extrinsic pathway 1.421754e-2
GO:0018199 peptidyl-glutamine modification 1.428320e-2
GO:0045930 negative regulation of mitotic cell cycle 1.428710e-2
GO:0006364 rRNA processing 1.451149e-2
GO:0007131 reciprocal meiotic recombination 1.452198e-2
GO:0072393 microtubule anchoring at microtubule organizing center 1.456084e-2
GO:0034380 high-density lipoprotein particle assembly 1.471386e-2
GO:0060923 cardiac muscle cell fate commitment 1.491892e-2


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0031442 positive regulation of mRNA 3'-end processing 1.944008e-9
GO:0006654 phosphatidic acid biosynthetic process 2.090752e-9
GO:0035621 ER to Golgi ceramide transport 2.150638e-9
GO:0009956 radial pattern formation 8.038317e-9
GO:0031440 regulation of mRNA 3'-end processing 2.562792e-8
GO:0045109 intermediate filament organization 2.792217e-8
GO:0045730 respiratory burst 3.313580e-8
GO:0060850 regulation of transcription involved in cell fate commitment 1.330505e-7
GO:0006297 nucleotide-excision repair, DNA gap filling 1.636296e-7
GO:0006119 oxidative phosphorylation 1.813740e-7
GO:0006650 glycerophospholipid metabolic process 4.850524e-7
GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment 5.306919e-7
GO:0061014 positive regulation of mRNA catabolic process 5.390062e-7
GO:0060839 endothelial cell fate commitment 8.335528e-7
GO:0060836 lymphatic endothelial cell differentiation 1.037666e-6
GO:0050685 positive regulation of mRNA processing 1.125610e-6
GO:0045087 innate immune response 1.247636e-6
GO:0031133 regulation of axon diameter 1.270602e-6
GO:0050832 defense response to fungus 1.492787e-6
GO:0051788 response to misfolded protein 1.865320e-6
GO:0046488 phosphatidylinositol metabolic process 1.940180e-6
GO:0032049 cardiolipin biosynthetic process 2.322705e-6
GO:0045128 negative regulation of reciprocal meiotic recombination 2.449178e-6
GO:0006311 meiotic gene conversion 2.449178e-6
GO:0018293 protein-FAD linkage 3.110542e-6
GO:0006121 mitochondrial electron transport, succinate to ubiquinone 3.110542e-6
GO:0032536 regulation of cell projection size 4.552956e-6
GO:0006515 misfolded or incompletely synthesized protein catabolic process 5.384841e-6
GO:0045104 intermediate filament cytoskeleton organization 5.598855e-6
GO:0071712 ER-associated misfolded protein catabolic process 5.971670e-6
GO:0030521 androgen receptor signaling pathway 7.140347e-6
GO:0051095 regulation of helicase activity 7.147172e-6
GO:0002827 positive regulation of T-helper 1 type immune response 8.683326e-6
GO:0042743 hydrogen peroxide metabolic process 9.439169e-6
GO:0071218 cellular response to misfolded protein 9.965379e-6
GO:0032048 cardiolipin metabolic process 9.965379e-6
GO:0045103 intermediate filament-based process 1.082740e-5
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 1.105457e-5
GO:0032094 response to food 1.177682e-5
GO:0045650 negative regulation of macrophage differentiation 1.225245e-5
GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling 1.225245e-5
GO:0006801 superoxide metabolic process 1.292069e-5
GO:0051096 positive regulation of helicase activity 1.347522e-5
GO:0060215 primitive hemopoiesis 1.779082e-5
GO:0034227 tRNA thio-modification 1.800085e-5
GO:0042035 regulation of cytokine biosynthetic process 2.040947e-5
GO:0046854 phosphatidylinositol phosphorylation 2.119014e-5
GO:0050748 negative regulation of lipoprotein metabolic process 2.235762e-5
GO:0002149 hypochlorous acid biosynthetic process 2.334594e-5
GO:0003158 endothelium development 2.873171e-5
GO:0043154 negative regulation of caspase activity 3.040438e-5
GO:0006982 response to lipid hydroperoxide 4.103634e-5
GO:0006370 mRNA capping 4.451218e-5
GO:0032922 circadian regulation of gene expression 4.662743e-5
GO:0006301 postreplication repair 5.474106e-5
GO:0042775 mitochondrial ATP synthesis coupled electron transport 5.616309e-5
GO:0072148 epithelial cell fate commitment 6.028651e-5
GO:0021892 cerebral cortex GABAergic interneuron differentiation 6.028651e-5
GO:0046834 lipid phosphorylation 6.066499e-5
GO:0006644 phospholipid metabolic process 6.113071e-5
GO:0021877 forebrain neuron fate commitment 6.625278e-5
GO:0019430 removal of superoxide radicals 7.139719e-5
GO:0009125 nucleoside monophosphate catabolic process 7.497393e-5
GO:0015802 basic amino acid transport 7.998986e-5
GO:0018192 enzyme active site formation via L-cysteine persulfide 8.001682e-5
GO:0070253 somatostatin secretion 8.303264e-5
GO:0032812 positive regulation of epinephrine secretion 8.303264e-5
GO:0042773 ATP synthesis coupled electron transport 8.390672e-5
GO:0002098 tRNA wobble uridine modification 8.490533e-5
GO:0045736 negative regulation of cyclin-dependent protein kinase activity 8.517331e-5
GO:0002227 innate immune response in mucosa 8.908249e-5
GO:0000303 response to superoxide 9.255491e-5
GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 9.374871e-5
GO:0009620 response to fungus 9.465384e-5
GO:0042538 hyperosmotic salinity response 9.573590e-5
GO:0000710 meiotic mismatch repair 9.872798e-5
GO:0061013 regulation of mRNA catabolic process 1.033379e-4
GO:0042744 hydrogen peroxide catabolic process 1.167863e-4
GO:0045686 negative regulation of glial cell differentiation 1.173480e-4
GO:0060631 regulation of meiosis I 1.216238e-4
GO:0032057 negative regulation of translational initiation in response to stress 1.396634e-4
GO:0030258 lipid modification 1.491187e-4
GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process 1.651483e-4
GO:0010898 positive regulation of triglyceride catabolic process 1.671434e-4
GO:0071340 skeletal muscle nicotinic acetylcholine receptor clustering 1.758645e-4
GO:0002679 respiratory burst involved in defense response 1.828177e-4
GO:0010520 regulation of reciprocal meiotic recombination 1.853777e-4
GO:0045076 regulation of interleukin-2 biosynthetic process 1.898488e-4
GO:0060029 convergent extension involved in organogenesis 1.908893e-4
GO:0048715 negative regulation of oligodendrocyte differentiation 1.981877e-4
GO:0002825 regulation of T-helper 1 type immune response 2.022672e-4
GO:0055090 acylglycerol homeostasis 2.045495e-4
GO:0046092 deoxycytidine metabolic process 2.094611e-4
GO:0032055 negative regulation of translation in response to stress 2.139117e-4
GO:0001887 selenium compound metabolic process 2.139117e-4
GO:0030224 monocyte differentiation 2.171962e-4
GO:0045835 negative regulation of meiosis 2.243818e-4
GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste 2.243818e-4
GO:0022617 extracellular matrix disassembly 2.243818e-4
GO:0014014 negative regulation of gliogenesis 2.284010e-4
GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity 2.297297e-4
GO:0060377 negative regulation of mast cell differentiation 2.297297e-4
GO:0002821 positive regulation of adaptive immune response 2.364865e-4
GO:0050913 sensory perception of bitter taste 2.443201e-4
GO:0008340 determination of adult lifespan 2.502885e-4
GO:0046426 negative regulation of JAK-STAT cascade 2.623814e-4
GO:0001573 ganglioside metabolic process 2.842881e-4
GO:0003139 secondary heart field specification 2.895686e-4
GO:0030321 transepithelial chloride transport 2.913554e-4
GO:0001878 response to yeast 2.927257e-4
GO:0046474 glycerophospholipid biosynthetic process 2.958978e-4
GO:2000178 negative regulation of neural precursor cell proliferation 3.261296e-4
GO:0035674 tricarboxylic acid transmembrane transport 3.311353e-4
GO:0071352 cellular response to interleukin-2 3.355176e-4
GO:0002561 basophil degranulation 3.355176e-4
GO:0032077 positive regulation of deoxyribonuclease activity 3.549907e-4
GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 3.549907e-4
GO:0000305 response to oxygen radical 3.976624e-4
GO:0006777 Mo-molybdopterin cofactor biosynthetic process 4.039857e-4
GO:0006659 phosphatidylserine biosynthetic process 4.055382e-4
GO:0045649 regulation of macrophage differentiation 4.055382e-4
GO:0048389 intermediate mesoderm development 4.115251e-4
GO:0072098 anterior/posterior pattern specification involved in kidney development 4.115251e-4
GO:0042732 D-xylose metabolic process 4.115251e-4
GO:0032425 positive regulation of mismatch repair 4.115251e-4
GO:0009452 RNA capping 4.327503e-4
GO:0009214 cyclic nucleotide catabolic process 4.398269e-4
GO:0031295 T cell costimulation 4.459906e-4
GO:0051100 negative regulation of binding 4.468439e-4
GO:0048609 multicellular organismal reproductive process 4.532551e-4
GO:0022007 convergent extension involved in neural plate elongation 4.584987e-4
GO:0046641 positive regulation of alpha-beta T cell proliferation 4.732270e-4
GO:0010596 negative regulation of endothelial cell migration 4.784291e-4
GO:0001945 lymph vessel development 4.804362e-4
GO:0045723 positive regulation of fatty acid biosynthetic process 4.807630e-4
GO:0010954 positive regulation of protein processing 5.166278e-4
GO:0060152 microtubule-based peroxisome localization 5.405335e-4
GO:0005997 xylulose metabolic process 5.413787e-4
GO:0045078 positive regulation of interferon-gamma biosynthetic process 5.430290e-4
GO:0034445 negative regulation of plasma lipoprotein particle oxidation 5.570724e-4
GO:0045662 negative regulation of myoblast differentiation 5.605131e-4
GO:0000003 reproduction 5.710044e-4
GO:0070093 negative regulation of glucagon secretion 5.716039e-4
GO:0033566 gamma-tubulin complex localization 5.716039e-4
GO:0019637 organophosphate metabolic process 5.750509e-4
GO:0060052 neurofilament cytoskeleton organization 5.758546e-4
GO:0002922 positive regulation of humoral immune response 6.038128e-4
GO:0045446 endothelial cell differentiation 6.094842e-4
GO:0019953 sexual reproduction 6.104647e-4
GO:0046486 glycerolipid metabolic process 6.180756e-4
GO:0021761 limbic system development 6.409744e-4
GO:0019985 translesion synthesis 6.492093e-4
GO:0032849 positive regulation of cellular pH reduction 6.902568e-4
GO:0006405 RNA export from nucleus 7.078953e-4
GO:0014060 regulation of epinephrine secretion 7.234231e-4
GO:0045575 basophil activation 7.387660e-4
GO:0060632 regulation of microtubule-based movement 7.538545e-4
GO:0042129 regulation of T cell proliferation 7.654024e-4
GO:0045409 negative regulation of interleukin-6 biosynthetic process 7.667012e-4
GO:0001967 suckling behavior 7.707477e-4
GO:0042108 positive regulation of cytokine biosynthetic process 7.839390e-4
GO:0072200 negative regulation of mesenchymal cell proliferation involved in ureter development 7.866424e-4
GO:0072198 mesenchymal cell proliferation involved in ureter development 7.866424e-4
GO:0072138 mesenchymal cell proliferation involved in ureteric bud development 7.866424e-4
GO:0072101 specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway 7.866424e-4
GO:0072192 ureter epithelial cell differentiation 7.866424e-4
GO:2000137 negative regulation of cell proliferation involved in heart morphogenesis 7.866424e-4
GO:2000007 negative regulation of metanephric comma-shaped body morphogenesis 7.866424e-4
GO:2000005 negative regulation of metanephric S-shaped body morphogenesis 7.866424e-4
GO:0090194 negative regulation of glomerulus development 7.866424e-4
GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis 7.866424e-4
GO:0060503 bud dilation involved in lung branching 7.866424e-4
GO:0055020 positive regulation of cardiac muscle fiber development 7.866424e-4
GO:0048392 intermediate mesodermal cell differentiation 7.866424e-4
GO:0035269 protein O-linked mannosylation 7.866424e-4
GO:0007500 mesodermal cell fate determination 7.866424e-4
GO:0072097 negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway 7.866424e-4
GO:0060502 epithelial cell proliferation involved in lung morphogenesis 7.866424e-4
GO:0071893 BMP signaling pathway involved in nephric duct formation 7.866424e-4
GO:0061149 BMP signaling pathway involved in ureter morphogenesis 7.866424e-4
GO:0061155 pulmonary artery endothelial tube morphogenesis 7.866424e-4
GO:0061151 BMP signaling pathway involved in renal system segmentation 7.866424e-4
GO:0034104 negative regulation of tissue remodeling 7.875861e-4
GO:0010613 positive regulation of cardiac muscle hypertrophy 7.875861e-4
GO:0032202 telomere assembly 7.923566e-4
GO:0016560 protein import into peroxisome matrix, docking 7.923566e-4
GO:0002885 positive regulation of hypersensitivity 8.023082e-4
GO:0044240 multicellular organismal lipid catabolic process 8.061452e-4
GO:0051457 maintenance of protein location in nucleus 8.095666e-4
GO:0008630 DNA damage response, signal transduction resulting in induction of apoptosis 8.217598e-4
GO:0006003 fructose 2,6-bisphosphate metabolic process 8.265974e-4
GO:0034442 regulation of lipoprotein oxidation 8.723134e-4
GO:0021978 telencephalon regionalization 8.731056e-4
GO:0031346 positive regulation of cell projection organization 8.767571e-4
GO:0035993 deltoid tuberosity development 8.963662e-4
GO:2000505 regulation of energy homeostasis 8.972965e-4
GO:0043134 regulation of hindgut contraction 9.227376e-4
GO:0006917 induction of apoptosis 9.289434e-4
GO:0012502 induction of programmed cell death 9.323612e-4
GO:0050746 regulation of lipoprotein metabolic process 1.008860e-3
GO:0006298 mismatch repair 1.008860e-3
GO:0021893 cerebral cortex GABAergic interneuron fate commitment 1.050619e-3
GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment 1.050619e-3
GO:0090179 planar cell polarity pathway involved in neural tube closure 1.077941e-3
GO:0045661 regulation of myoblast differentiation 1.078301e-3
GO:0006406 mRNA export from nucleus 1.114781e-3
GO:0021871 forebrain regionalization 1.118880e-3
GO:0042276 error-prone translesion synthesis 1.133465e-3
GO:0031331 positive regulation of cellular catabolic process 1.172715e-3
GO:0042771 DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis 1.175192e-3
GO:0044341 sodium-dependent phosphate transport 1.237836e-3
GO:0033211 adiponectin-mediated signaling pathway 1.260890e-3
GO:0060914 heart formation 1.299701e-3
GO:0007631 feeding behavior 1.306244e-3
GO:0002863 positive regulation of inflammatory response to antigenic stimulus 1.336167e-3
GO:0045923 positive regulation of fatty acid metabolic process 1.338434e-3
GO:0007207 activation of phospholipase C activity by muscarinic acetylcholine receptor signaling pathway 1.344573e-3
GO:0002542 Factor XII activation 1.344573e-3
GO:0007283 spermatogenesis 1.372058e-3
GO:0043091 L-arginine import 1.394499e-3
GO:0045342 MHC class II biosynthetic process 1.394499e-3
GO:0070839 divalent metal ion export 1.394499e-3
GO:0045751 negative regulation of Toll signaling pathway 1.394499e-3
GO:0035635 entry of bacterium into host cell 1.394499e-3
GO:0032632 interleukin-3 production 1.394499e-3
GO:0015707 nitrite transport 1.394499e-3
GO:0006876 cellular cadmium ion homeostasis 1.394499e-3
GO:0015761 mannose transport 1.394499e-3
GO:0008588 release of cytoplasmic sequestered NF-kappaB 1.404672e-3
GO:0072044 collecting duct development 1.430505e-3
GO:0046889 positive regulation of lipid biosynthetic process 1.456501e-3
GO:0017158 regulation of calcium ion-dependent exocytosis 1.500444e-3
GO:0035990 tendon cell differentiation 1.524915e-3
GO:0009642 response to light intensity 1.524915e-3
GO:0009629 response to gravity 1.566704e-3
GO:0050912 detection of chemical stimulus involved in sensory perception of taste 1.618929e-3
GO:0043570 maintenance of DNA repeat elements 1.618929e-3
GO:0015809 arginine transport 1.618929e-3
GO:0046660 female sex differentiation 1.621262e-3
GO:0001561 fatty acid alpha-oxidation 1.702580e-3
GO:0001764 neuron migration 1.708158e-3
GO:0051006 positive regulation of lipoprotein lipase activity 1.712969e-3
GO:0070301 cellular response to hydrogen peroxide 1.720966e-3
GO:0051919 positive regulation of fibrinolysis 1.757071e-3
GO:0042696 menarche 1.757071e-3
GO:0006379 mRNA cleavage 1.859349e-3
GO:0031573 intra-S DNA damage checkpoint 2.005138e-3
GO:0050863 regulation of T cell activation 2.032369e-3
GO:0018065 protein-cofactor linkage 2.048781e-3
GO:0051177 meiotic sister chromatid cohesion 2.069064e-3
GO:0032203 telomere formation via telomerase 2.069064e-3
GO:0000079 regulation of cyclin-dependent protein kinase activity 2.094149e-3
GO:0050665 hydrogen peroxide biosynthetic process 2.128269e-3
GO:0007276 gamete generation 2.140848e-3
GO:0042218 1-aminocyclopropane-1-carboxylate biosynthetic process 2.156632e-3
GO:0043524 negative regulation of neuron apoptosis 2.196265e-3
GO:0018963 phthalate metabolic process 2.217020e-3
GO:0021766 hippocampus development 2.222517e-3
GO:0006398 histone mRNA 3'-end processing 2.234437e-3
GO:0046545 development of primary female sexual characteristics 2.250051e-3
GO:0010721 negative regulation of cell development 2.267418e-3
GO:0051704 multi-organism process 2.276375e-3
GO:0010970 microtubule-based transport 2.346813e-3
GO:0060319 primitive erythrocyte differentiation 2.349548e-3
GO:2000522 positive regulation of immunological synapse formation 2.369407e-3
GO:0010259 multicellular organismal aging 2.413335e-3
GO:0009409 response to cold 2.440391e-3
GO:0022414 reproductive process 2.461830e-3
GO:0050772 positive regulation of axonogenesis 2.493769e-3
GO:0045779 negative regulation of bone resorption 2.503932e-3
GO:0021798 forebrain dorsal/ventral pattern formation 2.514635e-3
GO:0043056 forward locomotion 2.520911e-3
GO:0010288 response to lead ion 2.526460e-3
GO:0009187 cyclic nucleotide metabolic process 2.606927e-3
GO:0090185 negative regulation of kidney development 2.624176e-3
GO:0021759 globus pallidus development 2.624176e-3
GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus 2.635355e-3
GO:0001913 T cell mediated cytotoxicity 2.697834e-3
GO:0032107 regulation of response to nutrient levels 2.736703e-3
GO:0061005 cell differentiation involved in kidney development 2.742161e-3
GO:0010871 negative regulation of receptor biosynthetic process 2.751977e-3
GO:0001817 regulation of cytokine production 2.758827e-3
GO:2000507 positive regulation of energy homeostasis 2.765234e-3
GO:2000253 positive regulation of feeding behavior 2.765234e-3
GO:0002344 B cell affinity maturation 2.765234e-3
GO:0050917 sensory perception of umami taste 2.799072e-3
GO:0042036 negative regulation of cytokine biosynthetic process 2.800705e-3
GO:0007548 sex differentiation 2.853482e-3
GO:0072595 maintenance of protein localization to organelle 2.883077e-3
GO:0010611 regulation of cardiac muscle hypertrophy 2.898397e-3
GO:0015746 citrate transport 2.923637e-3
GO:0050829 defense response to Gram-negative bacterium 2.932880e-3
GO:0002579 positive regulation of antigen processing and presentation 2.938094e-3
GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 3.078030e-3
GO:0006167 AMP biosynthetic process 3.131122e-3
GO:0045085 negative regulation of interleukin-2 biosynthetic process 3.167248e-3
GO:0006646 phosphatidylethanolamine biosynthetic process 3.169056e-3
GO:0060340 positive regulation of type I interferon-mediated signaling pathway 3.180230e-3
GO:0047496 vesicle transport along microtubule 3.180230e-3
GO:0090138 regulation of actin cytoskeleton organization by cell-cell adhesion 3.183631e-3
GO:0046079 dUMP catabolic process 3.183631e-3
GO:0002883 regulation of hypersensitivity 3.196735e-3
GO:0043555 regulation of translation in response to stress 3.261043e-3
GO:0010388 cullin deneddylation 3.261043e-3
GO:0090031 positive regulation of steroid hormone biosynthetic process 3.426001e-3
GO:0051707 response to other organism 3.449960e-3
GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain 3.466840e-3
GO:0006867 asparagine transport 3.466840e-3
GO:0048663 neuron fate commitment 3.476012e-3
GO:0060026 convergent extension 3.479546e-3
GO:0071733 transcriptional activation by promoter-enhancer looping 3.489423e-3
GO:0043615 astrocyte cell migration 3.489423e-3
GO:0045072 regulation of interferon-gamma biosynthetic process 3.490686e-3
GO:0044130 negative regulation of growth of symbiont in host 3.591447e-3
GO:0007162 negative regulation of cell adhesion 3.614047e-3
GO:0002891 positive regulation of immunoglobulin mediated immune response 3.759715e-3
GO:0034720 histone H3-K4 demethylation 3.793698e-3
GO:0010092 specification of organ identity 3.894372e-3
GO:0072161 mesenchymal cell differentiation involved in kidney development 3.903990e-3
GO:0060684 epithelial-mesenchymal cell signaling 3.971168e-3
GO:0010896 regulation of triglyceride catabolic process 4.073033e-3
GO:0002762 negative regulation of myeloid leukocyte differentiation 4.169782e-3
GO:0010812 negative regulation of cell-substrate adhesion 4.172257e-3
GO:0046640 regulation of alpha-beta T cell proliferation 4.247685e-3
GO:0060586 multicellular organismal iron ion homeostasis 4.249220e-3
GO:0014807 regulation of somitogenesis 4.249220e-3
GO:0003270 Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation 4.249220e-3
GO:0016577 histone demethylation 4.269626e-3
GO:0080135 regulation of cellular response to stress 4.331724e-3
GO:0070169 positive regulation of biomineral tissue development 4.375931e-3
GO:0018879 biphenyl metabolic process 4.429635e-3
GO:0033131 regulation of glucokinase activity 4.432692e-3
GO:0003130 BMP signaling pathway involved in heart induction 4.441329e-3
GO:0008406 gonad development 4.584288e-3
GO:0045137 development of primary sexual characteristics 4.593140e-3
GO:0014743 regulation of muscle hypertrophy 4.747700e-3
GO:0046033 AMP metabolic process 4.755516e-3
GO:0007029 endoplasmic reticulum organization 4.790902e-3
GO:0021854 hypothalamus development 4.793404e-3
GO:0008088 axon cargo transport 4.836500e-3
GO:0046686 response to cadmium ion 4.896802e-3
GO:0045940 positive regulation of steroid metabolic process 4.955879e-3
GO:0006013 mannose metabolic process 4.982033e-3
GO:0035087 siRNA loading onto RISC involved in RNA interference 5.014109e-3
GO:0010836 negative regulation of protein ADP-ribosylation 5.014109e-3
GO:0010106 cellular response to iron ion starvation 5.014109e-3
GO:0001780 neutrophil homeostasis 5.016680e-3
GO:0001541 ovarian follicle development 5.157460e-3
GO:0035644 phosphoanandamide dephosphorylation 5.157982e-3
GO:0072593 reactive oxygen species metabolic process 5.171907e-3
GO:0061311 cell surface receptor linked signaling pathway involved in heart development 5.177456e-3
GO:0009607 response to biotic stimulus 5.309858e-3
GO:0045955 negative regulation of calcium ion-dependent exocytosis 5.329424e-3
GO:0090292 nuclear matrix anchoring at nuclear membrane 5.348082e-3
GO:0071422 succinate transmembrane transport 5.348082e-3
GO:0055114 oxidation-reduction process 5.515500e-3
GO:0060339 negative regulation of type I interferon-mediated signaling pathway 5.532056e-3
GO:0051705 behavioral interaction between organisms 5.759028e-3
GO:0016071 mRNA metabolic process 5.871487e-3
GO:0050768 negative regulation of neurogenesis 5.895346e-3
GO:0072384 organelle transport along microtubule 5.949810e-3
GO:0032570 response to progesterone stimulus 5.977198e-3
GO:0014012 peripheral nervous system axon regeneration 6.027429e-3
GO:0001909 leukocyte mediated cytotoxicity 6.027429e-3
GO:0009159 deoxyribonucleoside monophosphate catabolic process 6.031745e-3
GO:0033274 response to vitamin B2 6.031745e-3
GO:0002708 positive regulation of lymphocyte mediated immunity 6.094501e-3
GO:0045116 protein neddylation 6.255561e-3
GO:0043922 negative regulation by host of viral transcription 6.271937e-3
GO:0072205 metanephric collecting duct development 6.271937e-3
GO:0007159 leukocyte cell-cell adhesion 6.322372e-3
GO:0010720 positive regulation of cell development 6.477789e-3
GO:0035634 response to stilbenoid 6.628127e-3
GO:0070633 transepithelial transport 6.637382e-3
GO:0006658 phosphatidylserine metabolic process 6.706689e-3
GO:0050684 regulation of mRNA processing 6.837299e-3
GO:0002309 T cell proliferation involved in immune response 6.871963e-3
GO:0000395 nuclear mRNA 5'-splice site recognition 6.898186e-3
GO:0002573 myeloid leukocyte differentiation 6.901642e-3
GO:0010948 negative regulation of cell cycle process 6.910794e-3
GO:0007035 vacuolar acidification 6.978303e-3
GO:0032897 negative regulation of viral transcription 6.978438e-3
GO:0006749 glutathione metabolic process 7.085449e-3
GO:0010594 regulation of endothelial cell migration 7.180062e-3
GO:0006397 mRNA processing 7.234777e-3
GO:0015874 norepinephrine transport 7.298706e-3
GO:0006482 protein demethylation 7.337880e-3
GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism 7.352531e-3
GO:0018894 dibenzo-p-dioxin metabolic process 7.400399e-3
GO:0001798 positive regulation of type IIa hypersensitivity 7.400399e-3
GO:0055025 positive regulation of cardiac muscle tissue development 7.402641e-3
GO:0048511 rhythmic process 7.413102e-3
GO:0006661 phosphatidylinositol biosynthetic process 7.526766e-3
GO:0003219 cardiac right ventricle formation 7.664251e-3
GO:0016446 somatic hypermutation of immunoglobulin genes 7.746050e-3
GO:0070079 histone H4-R3 demethylation 7.836715e-3
GO:0070078 histone H3-R2 demethylation 7.836715e-3
GO:0018395 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine 7.836715e-3
GO:0050769 positive regulation of neurogenesis 7.986919e-3
GO:0002819 regulation of adaptive immune response 8.045493e-3
GO:0001768 establishment of T cell polarity 8.053440e-3
GO:0007626 locomotory behavior 8.091496e-3
GO:0051240 positive regulation of multicellular organismal process 8.132102e-3
GO:0043901 negative regulation of multi-organism process 8.165940e-3
GO:0032663 regulation of interleukin-2 production 8.372293e-3
GO:0040015 negative regulation of multicellular organism growth 8.408585e-3
GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity 8.439093e-3
GO:0043558 regulation of translational initiation in response to stress 8.439093e-3
GO:0035694 mitochondrial protein catabolic process 8.439093e-3
GO:0045618 positive regulation of keratinocyte differentiation 8.467592e-3
GO:0010889 regulation of sequestering of triglyceride 8.491778e-3
GO:0010976 positive regulation of neuron projection development 8.635956e-3
GO:0045638 negative regulation of myeloid cell differentiation 8.749131e-3
GO:0046125 pyrimidine deoxyribonucleoside metabolic process 8.762718e-3
GO:0002485 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent 8.762718e-3
GO:0015747 urate transport 8.762718e-3
GO:0071674 mononuclear cell migration 8.925941e-3
GO:0060335 positive regulation of interferon-gamma-mediated signaling pathway 8.925941e-3
GO:0010034 response to acetate 8.925941e-3
GO:0032070 regulation of deoxyribonuclease activity 8.925941e-3
GO:0006491 N-glycan processing 8.957097e-3
GO:0007221 positive regulation of transcription of Notch receptor target 8.962870e-3
GO:0050857 positive regulation of antigen receptor-mediated signaling pathway 8.978271e-3
GO:0045603 positive regulation of endothelial cell differentiation 9.072588e-3
GO:0002861 regulation of inflammatory response to antigenic stimulus 9.185562e-3
GO:0006750 glutathione biosynthetic process 9.231748e-3
GO:0072332 signal transduction by p53 class mediator resulting in induction of apoptosis 9.246384e-3
GO:0071900 regulation of protein serine/threonine kinase activity 9.418840e-3
GO:0048545 response to steroid hormone stimulus 9.595201e-3
GO:0050670 regulation of lymphocyte proliferation 9.652433e-3
GO:0033133 positive regulation of glucokinase activity 9.770989e-3
GO:0032308 positive regulation of prostaglandin secretion 9.770989e-3
GO:0046328 regulation of JNK cascade 9.822372e-3
GO:0050672 negative regulation of lymphocyte proliferation 9.986505e-3
GO:0045004 DNA replication proofreading 1.000148e-2
GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific 1.000148e-2
GO:0015939 pantothenate metabolic process 1.000148e-2
GO:0019047 provirus integration 1.000148e-2
GO:0045162 clustering of voltage-gated sodium channels 1.021185e-2
GO:0019348 dolichol metabolic process 1.021185e-2
GO:0090208 positive regulation of triglyceride metabolic process 1.025498e-2
GO:0070988 demethylation 1.027499e-2
GO:0034614 cellular response to reactive oxygen species 1.059716e-2
GO:0002864 regulation of acute inflammatory response to antigenic stimulus 1.063596e-2
GO:0009062 fatty acid catabolic process 1.066239e-2
GO:0090238 positive regulation of arachidonic acid secretion 1.069207e-2
GO:0035262 gonad morphogenesis 1.069207e-2
GO:0002125 maternal aggressive behavior 1.069207e-2
GO:0008380 RNA splicing 1.081255e-2
GO:0042274 ribosomal small subunit biogenesis 1.086409e-2
GO:0032892 positive regulation of organic acid transport 1.088311e-2
GO:0006972 hyperosmotic response 1.088311e-2
GO:0052312 modulation of transcription in other organism involved in symbiotic interaction 1.093134e-2
GO:0042770 signal transduction in response to DNA damage 1.100054e-2
GO:0019882 antigen processing and presentation 1.104398e-2
GO:0031247 actin rod assembly 1.121833e-2
GO:0032944 regulation of mononuclear cell proliferation 1.127971e-2
GO:0033058 directional locomotion 1.130462e-2
GO:0032680 regulation of tumor necrosis factor production 1.132451e-2
GO:0045404 positive regulation of interleukin-4 biosynthetic process 1.137512e-2
GO:0006672 ceramide metabolic process 1.142369e-2
GO:0031953 negative regulation of protein autophosphorylation 1.144514e-2
GO:0048710 regulation of astrocyte differentiation 1.146349e-2
GO:0072143 mesangial cell development 1.150234e-2
GO:0070584 mitochondrion morphogenesis 1.150234e-2
GO:0034629 cellular protein complex localization 1.150234e-2
GO:0009725 response to hormone stimulus 1.150580e-2
GO:0032355 response to estradiol stimulus 1.159210e-2
GO:0070302 regulation of stress-activated protein kinase signaling cascade 1.160247e-2
GO:0040014 regulation of multicellular organism growth 1.177030e-2
GO:0043523 regulation of neuron apoptosis 1.196016e-2
GO:0001956 positive regulation of neurotransmitter secretion 1.201841e-2
GO:0030099 myeloid cell differentiation 1.203276e-2
GO:0070664 negative regulation of leukocyte proliferation 1.209880e-2
GO:0045577 regulation of B cell differentiation 1.222347e-2
GO:0042542 response to hydrogen peroxide 1.228273e-2
GO:0071108 protein K48-linked deubiquitination 1.268501e-2
GO:0008343 adult feeding behavior 1.268501e-2
GO:0034372 very-low-density lipoprotein particle remodeling 1.271466e-2
GO:0048791 calcium ion-dependent exocytosis of neurotransmitter 1.283088e-2
GO:0046851 negative regulation of bone remodeling 1.283088e-2
GO:0030252 growth hormone secretion 1.295700e-2
GO:0042559 pteridine-containing compound biosynthetic process 1.295813e-2
GO:0007595 lactation 1.300379e-2
GO:0045778 positive regulation of ossification 1.305155e-2
GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway 1.348611e-2
GO:0035967 cellular response to topologically incorrect protein 1.350352e-2
GO:0022602 ovulation cycle process 1.359154e-2
GO:0050855 regulation of B cell receptor signaling pathway 1.372749e-2
GO:0009404 toxin metabolic process 1.383165e-2
GO:0042698 ovulation cycle 1.385073e-2
GO:0045017 glycerolipid biosynthetic process 1.386826e-2
GO:0021930 cerebellar granule cell precursor proliferation 1.388098e-2
GO:0032095 regulation of response to food 1.392405e-2
GO:0048668 collateral sprouting 1.393751e-2
GO:0015817 histidine transport 1.393751e-2
GO:0070663 regulation of leukocyte proliferation 1.403713e-2
GO:0060768 regulation of epithelial cell proliferation involved in prostate gland development 1.404760e-2
GO:0071157 negative regulation of cell cycle arrest 1.410507e-2
GO:0032847 regulation of cellular pH reduction 1.410507e-2