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Novel motif:11

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name:motif11_GCGANT

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0090304 nucleic acid metabolic process 9.785648e-14
GO:0016070 RNA metabolic process 2.177483e-12
GO:0010467 gene expression 2.363743e-11
GO:0070145 mitochondrial asparaginyl-tRNA aminoacylation 4.207133e-11
GO:0070127 tRNA aminoacylation for mitochondrial protein translation 2.650987e-10
GO:0032774 RNA biosynthetic process 4.453177e-10
GO:0034645 cellular macromolecule biosynthetic process 7.087149e-10
GO:0006351 transcription, DNA-dependent 9.989686e-10
GO:0090344 negative regulation of cell aging 3.873154e-9
GO:0009059 macromolecule biosynthetic process 8.082310e-9
GO:0018993 somatic sex determination 1.029644e-8
GO:0042703 menstruation 1.526232e-8
GO:0019101 female somatic sex determination 1.526232e-8
GO:0002074 extraocular skeletal muscle development 3.054101e-8
GO:0060976 coronary vasculature development 6.823395e-8
GO:0010771 negative regulation of cell morphogenesis involved in differentiation 1.680827e-7
GO:0030262 apoptotic nuclear change 1.973230e-7
GO:0022601 menstrual cycle phase 2.170602e-7
GO:0006139 nucleobase-containing compound metabolic process 2.209934e-7
GO:0090305 nucleic acid phosphodiester bond hydrolysis 3.785952e-7
GO:0035470 positive regulation of vascular wound healing 3.920453e-7
GO:0000416 positive regulation of histone H3-K36 methylation 7.005150e-7
GO:0033326 cerebrospinal fluid secretion 8.586066e-7
GO:0060260 regulation of transcription initiation from RNA polymerase II promoter 1.170705e-6
GO:0071934 thiamine transmembrane transport 1.208312e-6
GO:0006308 DNA catabolic process 1.775098e-6
GO:0006369 termination of RNA polymerase II transcription 1.814142e-6
GO:0060430 lung saccule development 2.307360e-6
GO:0032472 Golgi calcium ion transport 2.647295e-6
GO:0030026 cellular manganese ion homeostasis 2.647295e-6
GO:0032468 Golgi calcium ion homeostasis 2.647295e-6
GO:0010719 negative regulation of epithelial to mesenchymal transition 2.721571e-6
GO:0010871 negative regulation of receptor biosynthetic process 2.759228e-6
GO:0090342 regulation of cell aging 3.110080e-6
GO:0000413 protein peptidyl-prolyl isomerization 3.150744e-6
GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter 4.068174e-6
GO:0042538 hyperosmotic salinity response 5.442172e-6
GO:0032912 negative regulation of transforming growth factor beta2 production 5.590633e-6
GO:0000414 regulation of histone H3-K36 methylation 1.020732e-5
GO:0045714 regulation of low-density lipoprotein particle receptor biosynthetic process 1.042933e-5
GO:0010506 regulation of autophagy 1.368871e-5
GO:0016570 histone modification 1.429787e-5
GO:0018192 enzyme active site formation via L-cysteine persulfide 1.626791e-5
GO:0018872 arsonoacetate metabolic process 1.626791e-5
GO:0006309 DNA fragmentation involved in apoptotic nuclear change 1.693741e-5
GO:0014014 negative regulation of gliogenesis 1.716524e-5
GO:0043923 positive regulation by host of viral transcription 1.717535e-5
GO:0031123 RNA 3'-end processing 1.768288e-5
GO:0090102 cochlea development 1.827081e-5
GO:0044260 cellular macromolecule metabolic process 2.025335e-5
GO:0016569 covalent chromatin modification 2.069942e-5
GO:0010721 negative regulation of cell development 2.591736e-5
GO:0000959 mitochondrial RNA metabolic process 2.633486e-5
GO:0048713 regulation of oligodendrocyte differentiation 3.063423e-5
GO:0060014 granulosa cell differentiation 3.257000e-5
GO:0003310 pancreatic A cell differentiation 3.413695e-5
GO:0048561 establishment of organ orientation 3.577544e-5
GO:0043653 mitochondrial fragmentation involved in apoptosis 3.838518e-5
GO:0030237 female sex determination 3.838518e-5
GO:0003148 outflow tract septum morphogenesis 4.428788e-5
GO:0060947 cardiac vascular smooth muscle cell differentiation 4.526061e-5
GO:0051252 regulation of RNA metabolic process 4.556728e-5
GO:0035886 vascular smooth muscle cell differentiation 5.791836e-5
GO:0060486 Clara cell differentiation 5.864098e-5
GO:0007208 activation of phospholipase C activity by serotonin receptor signaling pathway 6.079300e-5
GO:0009404 toxin metabolic process 6.148042e-5
GO:0006355 regulation of transcription, DNA-dependent 6.966198e-5
GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity 7.364675e-5
GO:0065002 intracellular protein transmembrane transport 7.428523e-5
GO:0032042 mitochondrial DNA metabolic process 7.561485e-5
GO:0060980 cell migration involved in coronary vasculogenesis 7.566131e-5
GO:0035461 vitamin transmembrane transport 7.566131e-5
GO:0006302 double-strand break repair 7.627620e-5
GO:0060411 cardiac septum morphogenesis 8.083688e-5
GO:0090399 replicative senescence 8.154724e-5
GO:0000002 mitochondrial genome maintenance 8.584180e-5
GO:0000725 recombinational repair 9.288066e-5
GO:0000724 double-strand break repair via homologous recombination 9.491820e-5
GO:0006713 glucocorticoid catabolic process 9.833976e-5
GO:0006427 histidyl-tRNA aminoacylation 1.022055e-4
GO:0060712 spongiotrophoblast layer development 1.070824e-4
GO:0018293 protein-FAD linkage 1.075659e-4
GO:0006121 mitochondrial electron transport, succinate to ubiquinone 1.075659e-4
GO:0033523 histone H2B ubiquitination 1.079278e-4
GO:0071539 protein localization to centrosome 1.092384e-4
GO:0006359 regulation of transcription from RNA polymerase III promoter 1.136020e-4
GO:0051890 regulation of cardioblast differentiation 1.136020e-4
GO:0022027 interkinetic nuclear migration 1.161655e-4
GO:0006513 protein monoubiquitination 1.176855e-4
GO:0000022 mitotic spindle elongation 1.177733e-4
GO:0071322 cellular response to carbohydrate stimulus 1.240380e-4
GO:0021759 globus pallidus development 1.295406e-4
GO:0006268 DNA unwinding involved in replication 1.379806e-4
GO:0042696 menarche 1.402571e-4
GO:0090303 positive regulation of wound healing 1.422469e-4
GO:0007141 male meiosis I 1.422469e-4
GO:0045892 negative regulation of transcription, DNA-dependent 1.473381e-4
GO:0090141 positive regulation of mitochondrial fission 1.579393e-4
GO:0052312 modulation of transcription in other organism involved in symbiotic interaction 1.610869e-4
GO:0048752 semicircular canal morphogenesis 1.641598e-4
GO:0034198 cellular response to amino acid starvation 1.706971e-4
GO:0006281 DNA repair 1.746315e-4
GO:0030421 defecation 1.768894e-4
GO:0035356 cellular triglyceride homeostasis 1.768894e-4
GO:0003309 type B pancreatic cell differentiation 1.842121e-4
GO:0055012 ventricular cardiac muscle cell differentiation 2.004571e-4
GO:0071333 cellular response to glucose stimulus 2.015802e-4
GO:0032383 regulation of intracellular cholesterol transport 2.051591e-4
GO:0051891 positive regulation of cardioblast differentiation 2.058539e-4
GO:0003279 cardiac septum development 2.062908e-4
GO:0051253 negative regulation of RNA metabolic process 2.172424e-4
GO:0016480 negative regulation of transcription from RNA polymerase III promoter 2.256077e-4
GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process 2.294442e-4
GO:0000715 nucleotide-excision repair, DNA damage recognition 2.371072e-4
GO:0046784 intronless viral mRNA export from host nucleus 2.399763e-4
GO:0060708 spongiotrophoblast differentiation 2.524990e-4
GO:0048664 neuron fate determination 2.650912e-4
GO:0002016 regulation of blood volume by renin-angiotensin 2.698269e-4
GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor 2.730416e-4
GO:0018026 peptidyl-lysine monomethylation 2.780680e-4
GO:0060580 ventral spinal cord interneuron fate determination 2.809802e-4
GO:0003327 type B pancreatic cell fate commitment 2.809802e-4
GO:0003218 cardiac left ventricle formation 3.140122e-4
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation 3.283591e-4
GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing 3.283591e-4
GO:0006844 acyl carnitine transport 3.398709e-4
GO:0018208 peptidyl-proline modification 3.464187e-4
GO:0060596 mammary placode formation 3.631804e-4
GO:0043631 RNA polyadenylation 3.775128e-4
GO:0021530 spinal cord oligodendrocyte cell fate specification 3.966898e-4
GO:0010390 histone monoubiquitination 3.993697e-4
GO:0010629 negative regulation of gene expression 4.203211e-4
GO:0021604 cranial nerve structural organization 4.325982e-4
GO:0045686 negative regulation of glial cell differentiation 4.353674e-4
GO:0032392 DNA geometric change 4.375969e-4
GO:0000236 mitotic prometaphase 4.663337e-4
GO:0051083 'de novo' cotranslational protein folding 4.667663e-4
GO:0070159 mitochondrial threonyl-tRNA aminoacylation 4.701855e-4
GO:0002882 positive regulation of chronic inflammatory response to non-antigenic stimulus 4.701855e-4
GO:0043622 cortical microtubule organization 4.701855e-4
GO:0031658 negative regulation of cyclin-dependent protein kinase activity involved in G1/S 4.701855e-4
GO:0007092 activation of mitotic anaphase-promoting complex activity 4.701855e-4
GO:0030103 vasopressin secretion 4.701855e-4
GO:0010558 negative regulation of macromolecule biosynthetic process 4.928205e-4
GO:0035845 photoreceptor cell outer segment organization 4.981679e-4
GO:0010983 positive regulation of high-density lipoprotein particle clearance 4.981679e-4
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 5.009664e-4
GO:0009446 putrescine biosynthetic process 5.318934e-4
GO:2000615 regulation of histone H3-K9 acetylation 5.431450e-4
GO:0060510 Type II pneumocyte differentiation 6.036798e-4
GO:0003151 outflow tract morphogenesis 6.164186e-4
GO:0048714 positive regulation of oligodendrocyte differentiation 6.378048e-4
GO:0006481 C-terminal protein methylation 6.479560e-4
GO:0042984 regulation of amyloid precursor protein biosynthetic process 6.489600e-4
GO:0045685 regulation of glial cell differentiation 6.595789e-4
GO:0006378 mRNA polyadenylation 6.786361e-4
GO:2000113 negative regulation of cellular macromolecule biosynthetic process 6.873577e-4
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 6.876252e-4
GO:0031122 cytoplasmic microtubule organization 7.201044e-4
GO:0016574 histone ubiquitination 7.202207e-4
GO:0009086 methionine biosynthetic process 7.421434e-4
GO:0000966 RNA 5'-end processing 7.509299e-4
GO:0090140 regulation of mitochondrial fission 7.751763e-4
GO:0006289 nucleotide-excision repair 7.833264e-4
GO:0061084 negative regulation of protein refolding 7.851454e-4
GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 7.886399e-4
GO:0016140 O-glycoside metabolic process 8.017807e-4
GO:0035115 embryonic forelimb morphogenesis 8.337700e-4
GO:0021612 facial nerve structural organization 8.642693e-4
GO:0043000 Golgi to plasma membrane CFTR protein transport 9.184677e-4
GO:0000375 RNA splicing, via transesterification reactions 9.199354e-4
GO:0006493 protein O-linked glycosylation 9.247099e-4
GO:0031124 mRNA 3'-end processing 9.298239e-4
GO:0070535 histone H2A K63-linked ubiquitination 9.729706e-4
GO:0046210 nitric oxide catabolic process 9.729706e-4
GO:0090346 cellular organofluorine metabolic process 9.729706e-4
GO:0043602 nitrate catabolic process 9.729706e-4
GO:0035621 ER to Golgi ceramide transport 9.729706e-4
GO:0042732 D-xylose metabolic process 9.729706e-4
GO:0030330 DNA damage response, signal transduction by p53 class mediator 9.881287e-4
GO:0006270 DNA-dependent DNA replication initiation 9.986338e-4
GO:0016926 protein desumoylation 1.008388e-3
GO:0048486 parasympathetic nervous system development 1.011177e-3
GO:0014013 regulation of gliogenesis 1.030502e-3
GO:0035567 non-canonical Wnt receptor signaling pathway 1.049862e-3
GO:0010159 specification of organ position 1.086926e-3
GO:0070534 protein K63-linked ubiquitination 1.094629e-3
GO:0007199 G-protein signaling, coupled to cGMP nucleotide second messenger 1.111756e-3
GO:0042986 positive regulation of amyloid precursor protein biosynthetic process 1.111838e-3
GO:0032446 protein modification by small protein conjugation 1.185843e-3
GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition 1.234204e-3
GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation 1.234204e-3
GO:0042711 maternal behavior 1.283081e-3
GO:0000398 nuclear mRNA splicing, via spliceosome 1.306681e-3
GO:0002035 brain renin-angiotensin system 1.308918e-3
GO:0035117 embryonic arm morphogenesis 1.312225e-3
GO:0060412 ventricular septum morphogenesis 1.361174e-3
GO:0002115 store-operated calcium entry 1.408399e-3
GO:0046884 follicle-stimulating hormone secretion 1.409926e-3
GO:0032275 luteinizing hormone secretion 1.409926e-3
GO:0000729 DNA double-strand break processing 1.410167e-3
GO:0006264 mitochondrial DNA replication 1.464808e-3
GO:0051172 negative regulation of nitrogen compound metabolic process 1.488647e-3
GO:0051865 protein autoubiquitination 1.514835e-3
GO:0061351 neural precursor cell proliferation 1.523224e-3
GO:0090224 regulation of spindle organization 1.528923e-3
GO:0070584 mitochondrion morphogenesis 1.557414e-3
GO:0010890 positive regulation of sequestering of triglyceride 1.572174e-3
GO:0006290 pyrimidine dimer repair 1.572174e-3
GO:0050779 RNA destabilization 1.572454e-3
GO:0000097 sulfur amino acid biosynthetic process 1.573519e-3
GO:0021666 rhombomere 5 formation 1.581101e-3
GO:0021660 rhombomere 3 formation 1.581101e-3
GO:0071105 response to interleukin-11 1.615777e-3
GO:0042946 glucoside transport 1.615777e-3
GO:0019358 nicotinate nucleotide salvage 1.615777e-3
GO:0023035 CD40 signaling pathway 1.615777e-3
GO:0032508 DNA duplex unwinding 1.674551e-3
GO:0043921 modulation by host of viral transcription 1.720203e-3
GO:0021599 abducens nerve formation 1.818490e-3
GO:0007634 optokinetic behavior 1.818490e-3
GO:0042823 pyridoxal phosphate biosynthetic process 1.901625e-3
GO:0019348 dolichol metabolic process 1.901625e-3
GO:0007174 epidermal growth factor catabolic process 1.901625e-3
GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly 1.901625e-3
GO:2000620 positive regulation of histone H4-K16 acetylation 1.906015e-3
GO:2000617 positive regulation of histone H3-K9 acetylation 1.906015e-3
GO:0070625 zymogen granule exocytosis 1.906015e-3
GO:0070512 positive regulation of histone H4-K20 methylation 1.906015e-3
GO:0030505 inorganic diphosphate transport 1.910346e-3
GO:0035566 regulation of metanephros size 1.919203e-3
GO:0015870 acetylcholine transport 1.919203e-3
GO:0010701 positive regulation of norepinephrine secretion 1.919203e-3
GO:0016925 protein sumoylation 1.923835e-3
GO:0061001 regulation of dendritic spine morphogenesis 1.953489e-3
GO:2000465 regulation of glycogen (starch) synthase activity 2.057173e-3
GO:0050746 regulation of lipoprotein metabolic process 2.269619e-3
GO:0021783 preganglionic parasympathetic nervous system development 2.272114e-3
GO:0021892 cerebral cortex GABAergic interneuron differentiation 2.292347e-3
GO:0019509 L-methionine salvage from methylthioadenosine 2.292347e-3
GO:0042723 thiamine-containing compound metabolic process 2.294552e-3
GO:0006379 mRNA cleavage 2.296149e-3
GO:0021602 cranial nerve morphogenesis 2.335646e-3
GO:0060876 semicircular canal formation 2.351237e-3
GO:0048712 negative regulation of astrocyte differentiation 2.423348e-3
GO:0072300 positive regulation of metanephric glomerulus development 2.501786e-3
GO:0021603 cranial nerve formation 2.505235e-3
GO:0060253 negative regulation of glial cell proliferation 2.551620e-3
GO:0010735 positive regulation of transcription via serum response element binding 2.570850e-3
GO:0006348 chromatin silencing at telomere 2.571621e-3
GO:0043415 positive regulation of skeletal muscle tissue regeneration 2.585008e-3
GO:0016567 protein ubiquitination 2.659723e-3
GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter 2.780700e-3
GO:0042797 tRNA transcription from RNA polymerase III promoter 2.780700e-3
GO:0042843 D-xylose catabolic process 2.801690e-3
GO:0051571 positive regulation of histone H3-K4 methylation 2.826628e-3
GO:0003281 ventricular septum development 2.853926e-3
GO:0060872 semicircular canal development 2.865791e-3
GO:0072086 specification of loop of Henle identity 2.874787e-3
GO:0061013 regulation of mRNA catabolic process 2.913656e-3
GO:0042772 DNA damage response, signal transduction resulting in transcription 2.913656e-3
GO:0016568 chromatin modification 2.980253e-3
GO:0043697 cell dedifferentiation 3.006954e-3
GO:2000773 negative regulation of cellular senescence 3.006954e-3
GO:0030953 astral microtubule organization 3.006954e-3
GO:0051645 Golgi localization 3.071631e-3
GO:0006421 asparaginyl-tRNA aminoacylation 3.071631e-3
GO:0072272 proximal/distal pattern formation involved in metanephric nephron development 3.077267e-3
GO:0002017 regulation of blood volume by renal aldosterone 3.077267e-3
GO:0085020 protein K6-linked ubiquitination 3.077688e-3
GO:0048102 autophagic cell death 3.077688e-3
GO:0045116 protein neddylation 3.077688e-3
GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin 3.105485e-3
GO:0007158 neuron cell-cell adhesion 3.113728e-3
GO:0007501 mesodermal cell fate specification 3.138047e-3
GO:0001678 cellular glucose homeostasis 3.141660e-3
GO:0001941 postsynaptic membrane organization 3.194506e-3
GO:0090179 planar cell polarity pathway involved in neural tube closure 3.227265e-3
GO:0071476 cellular hypotonic response 3.249408e-3
GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly 3.256630e-3
GO:0015872 dopamine transport 3.288828e-3
GO:0060713 labyrinthine layer morphogenesis 3.337052e-3
GO:0043508 negative regulation of JUN kinase activity 3.352366e-3
GO:0090103 cochlea morphogenesis 3.364970e-3
GO:0042073 intraflagellar transport 3.483672e-3
GO:0009067 aspartate family amino acid biosynthetic process 3.582195e-3
GO:0035928 rRNA import into mitochondrion 3.586770e-3
GO:0000422 mitochondrion degradation 3.611667e-3
GO:0033182 regulation of histone ubiquitination 3.629010e-3
GO:0051315 attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation 3.629010e-3
GO:0006666 3-keto-sphinganine metabolic process 3.629010e-3
GO:0043401 steroid hormone mediated signaling pathway 3.707833e-3
GO:0002842 positive regulation of T cell mediated immune response to tumor cell 3.742288e-3
GO:0048291 isotype switching to IgG isotypes 3.742288e-3
GO:0002368 B cell cytokine production 3.742288e-3
GO:0006555 methionine metabolic process 3.751616e-3
GO:0060039 pericardium development 3.756068e-3
GO:0051973 positive regulation of telomerase activity 3.808871e-3
GO:0048388 endosomal lumen acidification 3.896471e-3
GO:0003326 pancreatic A cell fate commitment 3.896471e-3
GO:0003329 pancreatic PP cell fate commitment 3.896471e-3
GO:0021542 dentate gyrus development 3.920734e-3
GO:0007140 male meiosis 3.937474e-3
GO:0030488 tRNA methylation 3.987492e-3
GO:0015884 folic acid transport 3.991928e-3
GO:0032202 telomere assembly 3.991928e-3
GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation 4.033869e-3
GO:0042596 fear response 4.067954e-3
GO:0035357 peroxisome proliferator activated receptor signaling pathway 4.111589e-3
GO:0033057 multicellular organismal reproductive behavior 4.155046e-3
GO:0035441 cell migration involved in vasculogenesis 4.169912e-3
GO:0060592 mammary gland formation 4.230558e-3
GO:2000112 regulation of cellular macromolecule biosynthetic process 4.232796e-3
GO:0060998 regulation of dendritic spine development 4.361709e-3
GO:0009890 negative regulation of biosynthetic process 4.456602e-3
GO:0048691 positive regulation of axon extension involved in regeneration 4.479035e-3
GO:0019056 modulation by virus of host transcription 4.479035e-3
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 4.564661e-3
GO:0007181 transforming growth factor beta receptor complex assembly 4.565908e-3
GO:0030520 estrogen receptor signaling pathway 4.581348e-3
GO:0046602 regulation of mitotic centrosome separation 4.609794e-3
GO:0030388 fructose 1,6-bisphosphate metabolic process 4.685505e-3
GO:0090239 regulation of histone H4 acetylation 4.765613e-3
GO:0090035 positive regulation of cellular chaperone-mediated protein complex assembly 4.893474e-3
GO:0006501 C-terminal protein lipidation 4.982199e-3
GO:0007231 osmosensory signaling pathway 5.042351e-3
GO:0034641 cellular nitrogen compound metabolic process 5.075903e-3
GO:0071104 response to interleukin-9 5.081615e-3
GO:0045875 negative regulation of sister chromatid cohesion 5.081615e-3
GO:0060044 negative regulation of cardiac muscle cell proliferation 5.173569e-3
GO:0048532 anatomical structure arrangement 5.229279e-3
GO:0051276 chromosome organization 5.298003e-3
GO:0003181 atrioventricular valve morphogenesis 5.320049e-3
GO:0021571 rhombomere 5 development 5.331188e-3
GO:0051569 regulation of histone H3-K4 methylation 5.423888e-3
GO:0050748 negative regulation of lipoprotein metabolic process 5.447468e-3
GO:2000772 regulation of cellular senescence 5.504066e-3
GO:0055014 atrial cardiac muscle cell development 5.529754e-3
GO:0060977 coronary vasculature morphogenesis 5.529754e-3
GO:0048715 negative regulation of oligodendrocyte differentiation 5.544243e-3
GO:0045626 negative regulation of T-helper 1 cell differentiation 5.551219e-3
GO:0072331 signal transduction by p53 class mediator 5.640510e-3
GO:0001710 mesodermal cell fate commitment 5.689626e-3
GO:0001764 neuron migration 5.898398e-3
GO:0009304 tRNA transcription 5.911965e-3
GO:0002065 columnar/cuboidal epithelial cell differentiation 5.933224e-3
GO:0060383 positive regulation of DNA strand elongation 5.935611e-3
GO:0042694 muscle cell fate specification 5.935611e-3
GO:0051660 establishment of centrosome localization 5.935611e-3
GO:0042335 cuticle development 5.935611e-3
GO:0021540 corpus callosum morphogenesis 5.935611e-3
GO:0010986 positive regulation of lipoprotein particle clearance 5.935611e-3
GO:0009996 negative regulation of cell fate specification 6.042738e-3
GO:0006999 nuclear pore organization 6.087458e-3
GO:0016048 detection of temperature stimulus 6.138037e-3
GO:0021610 facial nerve morphogenesis 6.139089e-3
GO:0021895 cerebral cortex neuron differentiation 6.171627e-3
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity 6.219479e-3
GO:0010468 regulation of gene expression 6.244949e-3
GO:0042228 interleukin-8 biosynthetic process 6.285050e-3
GO:0000088 mitotic prophase 6.285050e-3
GO:0033342 negative regulation of collagen binding 6.285050e-3
GO:0008380 RNA splicing 6.294850e-3
GO:0046333 octopamine metabolic process 6.331215e-3
GO:0042309 homoiothermy 6.331215e-3
GO:0046950 cellular ketone body metabolic process 6.331380e-3
GO:0007422 peripheral nervous system development 6.358094e-3
GO:0034770 histone H4-K20 methylation 6.408837e-3
GO:0003206 cardiac chamber morphogenesis 6.551617e-3
GO:0097039 protein linear polyubiquitination 6.641896e-3
GO:0002678 positive regulation of chronic inflammatory response 6.786646e-3
GO:0035136 forelimb morphogenesis 6.899134e-3
GO:0061014 positive regulation of mRNA catabolic process 7.087373e-3
GO:0003323 type B pancreatic cell development 7.096367e-3
GO:2000467 positive regulation of glycogen (starch) synthase activity 7.293166e-3
GO:0070407 oxidation-dependent protein catabolic process 7.318351e-3
GO:0051106 positive regulation of DNA ligation 7.318351e-3
GO:2000252 negative regulation of feeding behavior 7.318351e-3
GO:0002033 vasodilation by angiotensin involved in regulation of systemic arterial blood pressure 7.318351e-3
GO:0019061 uncoating of virus 7.318351e-3
GO:0042414 epinephrine metabolic process 7.318351e-3
GO:0043456 regulation of pentose-phosphate shunt 7.341282e-3
GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation 7.341282e-3
GO:0035166 post-embryonic hemopoiesis 7.418881e-3
GO:0090234 regulation of kinetochore assembly 7.504813e-3
GO:0090169 regulation of spindle assembly 7.504813e-3
GO:0021846 cell proliferation in forebrain 7.536632e-3
GO:0006853 carnitine shuttle 7.672062e-3
GO:0006479 protein methylation 7.682371e-3
GO:2000119 negative regulation of sodium-dependent phosphate transport 7.804236e-3
GO:0034699 response to luteinizing hormone stimulus 7.804236e-3
GO:0008295 spermidine biosynthetic process 7.804236e-3
GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly 8.210944e-3
GO:0009443 pyridoxal 5'-phosphate salvage 8.210944e-3
GO:0042989 sequestering of actin monomers 8.275211e-3
GO:0000122 negative regulation of transcription from RNA polymerase II promoter 8.435862e-3
GO:0060706 cell differentiation involved in embryonic placenta development 8.441532e-3
GO:0071425 hemopoietic stem cell proliferation 8.525532e-3
GO:0044339 canonical Wnt receptor signaling pathway involved in osteoblast differentiation 8.568670e-3
GO:0044338 canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation 8.568670e-3
GO:0032543 mitochondrial translation 8.609603e-3
GO:0002209 behavioral defense response 8.628102e-3
GO:0035721 intraflagellar retrograde transport 8.719202e-3
GO:0051647 nucleus localization 8.728723e-3
GO:0000738 DNA catabolic process, exonucleolytic 8.736168e-3
GO:0021562 vestibulocochlear nerve development 9.033058e-3
GO:0034214 protein hexamerization 9.173304e-3
GO:0000726 non-recombinational repair 9.207801e-3
GO:0034695 response to prostaglandin E stimulus 9.418741e-3
GO:0050774 negative regulation of dendrite morphogenesis 9.819198e-3
GO:0032471 reduction of endoplasmic reticulum calcium ion concentration 9.909989e-3
GO:0051457 maintenance of protein location in nucleus 9.980167e-3
GO:0060304 regulation of phosphatidylinositol dephosphorylation 1.011353e-2
GO:0071279 cellular response to cobalt ion 1.011353e-2
GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process 1.011353e-2
GO:0032074 negative regulation of nuclease activity 1.011353e-2
GO:0031119 tRNA pseudouridine synthesis 1.011353e-2
GO:0010637 negative regulation of mitochondrial fusion 1.011353e-2
GO:0003416 endochondral bone growth 1.032119e-2
GO:0010560 positive regulation of glycoprotein biosynthetic process 1.034111e-2
GO:0032861 activation of Rap GTPase activity 1.057973e-2
GO:0018393 internal peptidyl-lysine acetylation 1.058234e-2
GO:0071985 multivesicular body sorting pathway 1.077582e-2
GO:0018022 peptidyl-lysine methylation 1.077582e-2
GO:0060648 mammary gland bud morphogenesis 1.098045e-2
GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase 1.098045e-2
GO:0048663 neuron fate commitment 1.102541e-2
GO:0001732 formation of translation initiation complex 1.112184e-2
GO:0032911 negative regulation of transforming growth factor beta1 production 1.117039e-2
GO:0010626 negative regulation of Schwann cell proliferation 1.119484e-2
GO:0046755 non-lytic virus budding 1.124498e-2
GO:0090219 negative regulation of lipid kinase activity 1.146707e-2
GO:0006499 N-terminal protein myristoylation 1.146707e-2
GO:0042631 cellular response to water deprivation 1.146707e-2
GO:0045739 positive regulation of DNA repair 1.157296e-2
GO:0015842 synaptic vesicle amine transport 1.173106e-2
GO:0035425 autocrine signaling 1.173106e-2
GO:0034498 early endosome to Golgi transport 1.188421e-2
GO:0030302 deoxynucleotide transport 1.188421e-2
GO:0060742 epithelial cell differentiation involved in prostate gland development 1.190793e-2
GO:0006261 DNA-dependent DNA replication 1.217577e-2
GO:0003166 bundle of His development 1.217960e-2
GO:0060687 regulation of branching involved in prostate gland morphogenesis 1.236146e-2
GO:0045819 positive regulation of glycogen catabolic process 1.239544e-2
GO:0021561 facial nerve development 1.257756e-2
GO:0003417 growth plate cartilage development 1.269156e-2
GO:0045403 negative regulation of interleukin-4 biosynthetic process 1.273069e-2
GO:0034351 negative regulation of glial cell apoptosis 1.273069e-2
GO:0060377 negative regulation of mast cell differentiation 1.273069e-2
GO:0002295 T-helper cell lineage commitment 1.273069e-2
GO:0003195 tricuspid valve formation 1.273069e-2
GO:0003192 mitral valve formation 1.273069e-2
GO:0001662 behavioral fear response 1.275369e-2
GO:0046605 regulation of centrosome cycle 1.301079e-2
GO:0072081 specification of nephron tubule identity 1.312472e-2
GO:0050768 negative regulation of neurogenesis 1.328083e-2
GO:0044249 cellular biosynthetic process 1.331504e-2
GO:0034644 cellular response to UV 1.332719e-2
GO:0018394 peptidyl-lysine acetylation 1.340576e-2
GO:0060669 embryonic placenta morphogenesis 1.344214e-2
GO:0032224 positive regulation of synaptic transmission, cholinergic 1.377938e-2
GO:0046939 nucleotide phosphorylation 1.383665e-2
GO:0018027 peptidyl-lysine dimethylation 1.386891e-2
GO:0032203 telomere formation via telomerase 1.386891e-2
GO:0005981 regulation of glycogen catabolic process 1.399574e-2
GO:0035435 phosphate ion transmembrane transport 1.409870e-2
GO:0002118 aggressive behavior 1.410381e-2
GO:0010950 positive regulation of endopeptidase activity 1.410381e-2
GO:0018230 peptidyl-L-cysteine S-palmitoylation 1.420917e-2
GO:0010266 response to vitamin B1 1.420917e-2
GO:0090129 positive regulation of synapse maturation 1.422413e-2
GO:0006686 sphingomyelin biosynthetic process 1.426252e-2
GO:0071866 negative regulation of apoptosis in bone marrow 1.431815e-2
GO:0071864 positive regulation of cell proliferation in bone marrow 1.431815e-2
GO:0071482 cellular response to light stimulus 1.445753e-2
GO:0006595 polyamine metabolic process 1.445753e-2
GO:0031327 negative regulation of cellular biosynthetic process 1.496942e-2
GO:0042418 epinephrine biosynthetic process 1.497529e-2
GO:0042780 tRNA 3'-end processing 1.497529e-2
GO:2000768 positive regulation of nephron tubule epithelial cell differentiation 1.497529e-2
GO:0035852 horizontal cell localization 1.497529e-2
GO:0048855 adenohypophysis morphogenesis 1.497529e-2
GO:0031118 rRNA pseudouridine synthesis 1.497529e-2
GO:0006585 dopamine biosynthetic process from tyrosine 1.497529e-2
GO:0035502 metanephric ureteric bud development 1.497529e-2
GO:0035846 oviduct epithelium development 1.497529e-2
GO:0035849 nephric duct elongation 1.497529e-2
GO:0035847 uterine epithelium development 1.497529e-2
GO:0035090 maintenance of apical/basal cell polarity 1.526457e-2
GO:0061302 smooth muscle cell-matrix adhesion 1.534457e-2
GO:0045472 response to ether 1.534457e-2
GO:0032205 negative regulation of telomere maintenance 1.543315e-2
GO:0052066 entry of symbiont into host cell by promotion of host phagocytosis 1.545530e-2
GO:0060060 post-embryonic retina morphogenesis in camera-type eye 1.545530e-2
GO:0035635 entry of bacterium into host cell 1.545530e-2
GO:0046358 butyrate biosynthetic process 1.545530e-2
GO:0033566 gamma-tubulin complex localization 1.545530e-2
GO:0090128 regulation of synapse maturation 1.578579e-2
GO:0018410 C-terminal protein amino acid modification 1.591586e-2
GO:0046174 polyol catabolic process 1.611574e-2


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0006396 RNA processing 1.047096e-12
GO:0051891 positive regulation of cardioblast differentiation 4.999865e-10
GO:0006397 mRNA processing 1.497584e-9
GO:0008380 RNA splicing 1.676715e-9
GO:0016071 mRNA metabolic process 8.980478e-9
GO:0051890 regulation of cardioblast differentiation 1.303776e-8
GO:0006268 DNA unwinding involved in replication 1.520012e-8
GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator 9.315404e-8
GO:0090304 nucleic acid metabolic process 1.005139e-7
GO:0032508 DNA duplex unwinding 1.585576e-7
GO:0032392 DNA geometric change 2.977910e-7
GO:0032912 negative regulation of transforming growth factor beta2 production 3.149625e-7
GO:0006540 glutamate decarboxylation to succinate 3.390562e-7
GO:0006261 DNA-dependent DNA replication 4.471442e-7
GO:0022402 cell cycle process 5.507341e-7
GO:0031508 centromeric heterochromatin formation 6.524530e-7
GO:0045666 positive regulation of neuron differentiation 7.570158e-7
GO:0016070 RNA metabolic process 7.673208e-7
GO:0003309 type B pancreatic cell differentiation 8.197456e-7
GO:0010467 gene expression 1.262798e-6
GO:0006260 DNA replication 1.352369e-6
GO:0090234 regulation of kinetochore assembly 1.574817e-6
GO:0090169 regulation of spindle assembly 1.574817e-6
GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint 1.634354e-6
GO:0060045 positive regulation of cardiac muscle cell proliferation 1.922301e-6
GO:0085020 protein K6-linked ubiquitination 2.113415e-6
GO:0072040 negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis 2.796691e-6
GO:0042254 ribosome biogenesis 2.934493e-6
GO:0000086 G2/M transition of mitotic cell cycle 3.000624e-6
GO:0000278 mitotic cell cycle 3.155063e-6
GO:0042136 neurotransmitter biosynthetic process 3.239917e-6
GO:0060043 regulation of cardiac muscle cell proliferation 3.992155e-6
GO:0030513 positive regulation of BMP signaling pathway 4.536171e-6
GO:0007493 endodermal cell fate determination 4.608369e-6
GO:0051726 regulation of cell cycle 5.083899e-6
GO:0022403 cell cycle phase 9.043701e-6
GO:0006297 nucleotide-excision repair, DNA gap filling 9.218843e-6
GO:0007141 male meiosis I 1.178817e-5
GO:0090231 regulation of spindle checkpoint 1.193761e-5
GO:0000080 G1 phase of mitotic cell cycle 1.204441e-5
GO:0046853 inositol or phosphatidylinositol phosphorylation 1.368831e-5
GO:0006538 glutamate catabolic process 1.730079e-5
GO:0031577 spindle checkpoint 1.998747e-5
GO:0035621 ER to Golgi ceramide transport 2.078085e-5
GO:0003310 pancreatic A cell differentiation 2.212185e-5
GO:0006139 nucleobase-containing compound metabolic process 2.220628e-5
GO:0016072 rRNA metabolic process 2.382716e-5
GO:0061013 regulation of mRNA catabolic process 2.550978e-5
GO:0000726 non-recombinational repair 2.800215e-5
GO:0021562 vestibulocochlear nerve development 3.231594e-5
GO:0045931 positive regulation of mitotic cell cycle 3.268577e-5
GO:0090193 positive regulation of glomerulus development 3.517402e-5
GO:0060947 cardiac vascular smooth muscle cell differentiation 4.208364e-5
GO:0060795 cell fate commitment involved in formation of primary germ layers 4.225463e-5
GO:0006657 CDP-choline pathway 4.373246e-5
GO:0055021 regulation of cardiac muscle tissue growth 4.659277e-5
GO:0022613 ribonucleoprotein complex biogenesis 4.756634e-5
GO:0035886 vascular smooth muscle cell differentiation 5.040265e-5
GO:0071169 establishment of protein localization to chromatin 5.584497e-5
GO:0045078 positive regulation of interferon-gamma biosynthetic process 5.710903e-5
GO:0044265 cellular macromolecule catabolic process 5.780036e-5
GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing 5.979212e-5
GO:0033031 positive regulation of neutrophil apoptosis 6.301936e-5
GO:0070165 positive regulation of adiponectin secretion 6.301936e-5
GO:0006308 DNA catabolic process 6.840239e-5
GO:0071843 cellular component biogenesis at cellular level 7.671880e-5
GO:0045072 regulation of interferon-gamma biosynthetic process 7.917338e-5
GO:0007049 cell cycle 9.324830e-5
GO:0003148 outflow tract septum morphogenesis 9.387677e-5
GO:0051329 interphase of mitotic cell cycle 1.013098e-4
GO:0032465 regulation of cytokinesis 1.021745e-4
GO:2000594 positive regulation of metanephric DCT cell differentiation 1.093012e-4
GO:0072305 negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis 1.093012e-4
GO:0039003 pronephric field specification 1.093012e-4
GO:0001711 endodermal cell fate commitment 1.103682e-4
GO:0034661 ncRNA catabolic process 1.170912e-4
GO:0034446 substrate adhesion-dependent cell spreading 1.176136e-4
GO:0051030 snRNA transport 1.190684e-4
GO:0046416 D-amino acid metabolic process 1.190684e-4
GO:0060411 cardiac septum morphogenesis 1.243796e-4
GO:0072300 positive regulation of metanephric glomerulus development 1.386563e-4
GO:0051318 G1 phase 1.493556e-4
GO:0006364 rRNA processing 1.561927e-4
GO:0003279 cardiac septum development 1.645842e-4
GO:0032911 negative regulation of transforming growth factor beta1 production 1.673001e-4
GO:0072003 kidney rudiment formation 1.708894e-4
GO:0014010 Schwann cell proliferation 1.708894e-4
GO:0018243 protein O-linked glycosylation via threonine 1.809295e-4
GO:0018242 protein O-linked glycosylation via serine 1.809295e-4
GO:0051297 centrosome organization 1.810631e-4
GO:0019428 allantoin biosynthetic process 1.957979e-4
GO:0006366 transcription from RNA polymerase II promoter 1.996621e-4
GO:0051325 interphase 2.041274e-4
GO:0061360 optic chiasma development 2.204943e-4
GO:2000597 positive regulation of optic nerve formation 2.204943e-4
GO:0021650 vestibulocochlear nerve formation 2.204943e-4
GO:0035799 ureter maturation 2.204943e-4
GO:0021633 optic nerve structural organization 2.204943e-4
GO:0001709 cell fate determination 2.231171e-4
GO:0032908 regulation of transforming growth factor beta1 production 2.295567e-4
GO:0006259 DNA metabolic process 2.401689e-4
GO:0009452 RNA capping 2.441800e-4
GO:0000237 leptotene 2.533517e-4
GO:0072205 metanephric collecting duct development 2.613612e-4
GO:0070534 protein K63-linked ubiquitination 2.659318e-4
GO:0044260 cellular macromolecule metabolic process 2.684548e-4
GO:0070830 tight junction assembly 2.906320e-4
GO:0090224 regulation of spindle organization 3.238779e-4
GO:0046491 L-methylmalonyl-CoA metabolic process 3.325888e-4
GO:0016078 tRNA catabolic process 3.325888e-4
GO:0001682 tRNA 5'-leader removal 3.325888e-4
GO:0055024 regulation of cardiac muscle tissue development 3.387387e-4
GO:0021884 forebrain neuron development 3.459446e-4
GO:0006413 translational initiation 3.477753e-4
GO:0048645 organ formation 3.484147e-4
GO:0034587 piRNA metabolic process 3.726247e-4
GO:0003197 endocardial cushion development 3.746132e-4
GO:0007099 centriole replication 3.840955e-4
GO:0071034 CUT catabolic process 3.843990e-4
GO:0048286 lung alveolus development 3.849324e-4
GO:0071173 spindle assembly checkpoint 3.882960e-4
GO:2000036 regulation of stem cell maintenance 3.997796e-4
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis 4.251243e-4
GO:0071777 positive regulation of cell cycle cytokinesis 4.612482e-4
GO:0006289 nucleotide-excision repair 4.659006e-4
GO:0060575 intestinal epithelial cell differentiation 4.672281e-4
GO:0050668 positive regulation of homocysteine metabolic process 4.700843e-4
GO:0045963 negative regulation of dopamine metabolic process 4.700843e-4
GO:0001704 formation of primary germ layer 4.707828e-4
GO:0007140 male meiosis 4.795595e-4
GO:0010564 regulation of cell cycle process 5.299098e-4
GO:0070079 histone H4-R3 demethylation 5.319094e-4
GO:0070078 histone H3-R2 demethylation 5.319094e-4
GO:0018395 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine 5.319094e-4
GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity 5.319094e-4
GO:0022417 protein maturation by protein folding 5.319094e-4
GO:0046882 negative regulation of follicle-stimulating hormone secretion 5.356314e-4
GO:0046426 negative regulation of JAK-STAT cascade 5.418390e-4
GO:0031023 microtubule organizing center organization 5.422172e-4
GO:0035987 endodermal cell differentiation 5.438966e-4
GO:0016926 protein desumoylation 5.548893e-4
GO:0006405 RNA export from nucleus 5.682688e-4
GO:0034470 ncRNA processing 6.293750e-4
GO:0007214 gamma-aminobutyric acid signaling pathway 6.299829e-4
GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine 6.368052e-4
GO:0007067 mitosis 6.462328e-4
GO:0000087 M phase of mitotic cell cycle 6.556119e-4
GO:0000279 M phase 7.297487e-4
GO:0000729 DNA double-strand break processing 7.395326e-4
GO:0045741 positive regulation of epidermal growth factor-activated receptor activity 7.476070e-4
GO:0014047 glutamate secretion 7.587529e-4
GO:0008608 attachment of spindle microtubules to kinetochore 7.667455e-4
GO:0051176 positive regulation of sulfur metabolic process 7.863915e-4
GO:0031055 chromatin remodeling at centromere 7.911064e-4
GO:0021603 cranial nerve formation 7.959298e-4
GO:0048285 organelle fission 8.140105e-4
GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 8.824365e-4
GO:0030510 regulation of BMP signaling pathway 8.976776e-4
GO:0001835 blastocyst hatching 9.667546e-4
GO:0003339 regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 1.003660e-3
GO:0042360 vitamin E metabolic process 1.008534e-3
GO:0002638 negative regulation of immunoglobulin production 1.024448e-3
GO:0001811 negative regulation of type I hypersensitivity 1.024448e-3
GO:0031442 positive regulation of mRNA 3'-end processing 1.024587e-3
GO:0061014 positive regulation of mRNA catabolic process 1.070566e-3
GO:0035425 autocrine signaling 1.100482e-3
GO:0003151 outflow tract morphogenesis 1.111051e-3
GO:0070194 synaptonemal complex disassembly 1.129681e-3
GO:0070179 D-serine biosynthetic process 1.129681e-3
GO:0043297 apical junction assembly 1.139637e-3
GO:0000079 regulation of cyclin-dependent protein kinase activity 1.155009e-3
GO:0006309 DNA fragmentation involved in apoptotic nuclear change 1.171181e-3
GO:0072594 establishment of protein localization to organelle 1.182203e-3
GO:0051298 centrosome duplication 1.200162e-3
GO:0007389 pattern specification process 1.206331e-3
GO:0071156 regulation of cell cycle arrest 1.210863e-3
GO:0051457 maintenance of protein location in nucleus 1.225996e-3
GO:0019377 glycolipid catabolic process 1.246680e-3
GO:0042996 regulation of Golgi to plasma membrane protein transport 1.354972e-3
GO:0050779 RNA destabilization 1.396527e-3
GO:0016075 rRNA catabolic process 1.396527e-3
GO:0060420 regulation of heart growth 1.462229e-3
GO:0071635 negative regulation of transforming growth factor beta production 1.499947e-3
GO:0021758 putamen development 1.541633e-3
GO:0021757 caudate nucleus development 1.541633e-3
GO:0006511 ubiquitin-dependent protein catabolic process 1.542842e-3
GO:0090049 regulation of cell migration involved in sprouting angiogenesis 1.549101e-3
GO:0030262 apoptotic nuclear change 1.560970e-3
GO:0090192 regulation of glomerulus development 1.589698e-3
GO:0043415 positive regulation of skeletal muscle tissue regeneration 1.603770e-3
GO:0034660 ncRNA metabolic process 1.632910e-3
GO:0071174 mitotic cell cycle spindle checkpoint 1.651917e-3
GO:0072307 regulation of metanephric nephron tubule epithelial cell differentiation 1.660239e-3
GO:0030071 regulation of mitotic metaphase/anaphase transition 1.733009e-3
GO:0007346 regulation of mitotic cell cycle 1.761452e-3
GO:0090082 positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway 1.765805e-3
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 1.765805e-3
GO:0021797 forebrain anterior/posterior pattern specification 1.779041e-3
GO:0006614 SRP-dependent cotranslational protein targeting to membrane 1.844715e-3
GO:0032060 bleb assembly 1.885207e-3
GO:0001706 endoderm formation 1.901951e-3
GO:0009057 macromolecule catabolic process 1.923128e-3
GO:0030163 protein catabolic process 1.925942e-3
GO:0007501 mesodermal cell fate specification 1.987888e-3
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 1.987888e-3
GO:0042268 regulation of cytolysis 2.021401e-3
GO:0071158 positive regulation of cell cycle arrest 2.099781e-3
GO:0006306 DNA methylation 2.109005e-3
GO:0032467 positive regulation of cytokinesis 2.170388e-3
GO:0007223 Wnt receptor signaling pathway, calcium modulating pathway 2.170388e-3
GO:0051145 smooth muscle cell differentiation 2.226367e-3
GO:0090286 cytoskeletal anchoring at nuclear membrane 2.271357e-3
GO:0034441 plasma lipoprotein particle oxidation 2.276637e-3
GO:0001555 oocyte growth 2.276637e-3
GO:0035330 regulation of hippo signaling cascade 2.326089e-3
GO:0030521 androgen receptor signaling pathway 2.341503e-3
GO:0090042 tubulin deacetylation 2.405533e-3
GO:0070846 Hsp90 deacetylation 2.405533e-3
GO:0042998 positive regulation of Golgi to plasma membrane protein transport 2.405533e-3
GO:0006780 uroporphyrinogen III biosynthetic process 2.405533e-3
GO:0032365 intracellular lipid transport 2.454012e-3
GO:0019941 modification-dependent protein catabolic process 2.463579e-3
GO:0045736 negative regulation of cyclin-dependent protein kinase activity 2.538819e-3
GO:0050685 positive regulation of mRNA processing 2.627610e-3
GO:0043484 regulation of RNA splicing 2.705217e-3
GO:0007619 courtship behavior 2.718576e-3
GO:0071108 protein K48-linked deubiquitination 2.823018e-3
GO:0006406 mRNA export from nucleus 2.845524e-3
GO:0043632 modification-dependent macromolecule catabolic process 2.888676e-3
GO:0060649 mammary gland bud elongation 2.899561e-3
GO:0060659 nipple sheath formation 2.899561e-3
GO:0060003 copper ion export 2.899561e-3
GO:0015677 copper ion import 2.899561e-3
GO:0006921 cellular component disassembly involved in apoptosis 2.920447e-3
GO:0032277 negative regulation of gonadotropin secretion 2.932595e-3
GO:0031584 activation of phospholipase D activity 2.932595e-3
GO:0051603 proteolysis involved in cellular protein catabolic process 2.957803e-3
GO:2000768 positive regulation of nephron tubule epithelial cell differentiation 3.018220e-3
GO:0035852 horizontal cell localization 3.018220e-3
GO:0035849 nephric duct elongation 3.018220e-3
GO:0035846 oviduct epithelium development 3.018220e-3
GO:0035847 uterine epithelium development 3.018220e-3
GO:0046605 regulation of centrosome cycle 3.142686e-3
GO:0006493 protein O-linked glycosylation 3.203131e-3
GO:0003406 retinal pigment epithelium development 3.264775e-3
GO:0033600 negative regulation of mammary gland epithelial cell proliferation 3.475975e-3
GO:0021516 dorsal spinal cord development 3.663167e-3
GO:0019376 galactolipid catabolic process 3.694655e-3
GO:0007094 mitotic cell cycle spindle assembly checkpoint 3.694655e-3
GO:0006408 snRNA export from nucleus 3.830644e-3
GO:0002663 positive regulation of B cell tolerance induction 3.944121e-3
GO:0021549 cerebellum development 3.967163e-3
GO:0090399 replicative senescence 4.009511e-3
GO:0014051 gamma-aminobutyric acid secretion 4.083635e-3
GO:0072520 seminiferous tubule development 4.265834e-3
GO:0071476 cellular hypotonic response 4.265834e-3
GO:0035566 regulation of metanephros size 4.265834e-3
GO:0006302 double-strand break repair 4.290081e-3
GO:0065004 protein-DNA complex assembly 4.399407e-3
GO:0046102 inosine metabolic process 4.516142e-3
GO:0035519 protein K29-linked ubiquitination 4.516142e-3
GO:0006613 cotranslational protein targeting to membrane 4.545796e-3
GO:0051973 positive regulation of telomerase activity 4.561021e-3
GO:0060658 nipple morphogenesis 4.561021e-3
GO:0045918 negative regulation of cytolysis 4.561021e-3
GO:0060540 diaphragm morphogenesis 4.690855e-3
GO:0060464 lung lobe formation 4.690855e-3
GO:0072289 metanephric nephron tubule formation 4.718778e-3
GO:0070625 zymogen granule exocytosis 4.768594e-3
GO:0044314 protein K27-linked ubiquitination 4.768594e-3
GO:0070163 regulation of adiponectin secretion 4.768594e-3
GO:0000059 protein import into nucleus, docking 4.768594e-3
GO:0018214 protein carboxylation 4.768594e-3
GO:0034641 cellular nitrogen compound metabolic process 4.835156e-3
GO:2000623 negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 5.086506e-3
GO:0071218 cellular response to misfolded protein 5.086506e-3
GO:0042667 auditory receptor cell fate specification 5.120654e-3
GO:0045609 positive regulation of auditory receptor cell differentiation 5.120654e-3
GO:0060975 cardioblast migration to the midline involved in heart field formation 5.120654e-3
GO:0035481 positive regulation of Notch signaling pathway involved in heart induction 5.120654e-3
GO:0034230 enkephalin processing 5.120654e-3
GO:0034231 islet amyloid polypeptide processing 5.120654e-3
GO:0003259 cardioblast anterior-lateral migration 5.120654e-3
GO:0003236 sinus venosus morphogenesis 5.120654e-3
GO:0003210 cardiac atrium formation 5.120654e-3
GO:0033152 immunoglobulin V(D)J recombination 5.165545e-3
GO:0023019 signal transduction involved in regulation of gene expression 5.262562e-3
GO:0031440 regulation of mRNA 3'-end processing 5.408037e-3
GO:0007398 ectoderm development 5.412675e-3
GO:0022617 extracellular matrix disassembly 5.549513e-3
GO:0051496 positive regulation of stress fiber assembly 5.770840e-3
GO:0072215 regulation of metanephros development 6.141467e-3
GO:0032507 maintenance of protein location in cell 6.164492e-3
GO:0044257 cellular protein catabolic process 6.173666e-3
GO:0006515 misfolded or incompletely synthesized protein catabolic process 6.194198e-3
GO:0070562 regulation of vitamin D receptor signaling pathway 6.224474e-3
GO:0002030 inhibitory G-protein coupled receptor phosphorylation 6.224474e-3
GO:0001705 ectoderm formation 6.224474e-3
GO:0072560 type B pancreatic cell maturation 6.249596e-3
GO:0003283 atrial septum development 6.352118e-3
GO:0060466 activation of meiosis involved in egg activation 6.519997e-3
GO:0000738 DNA catabolic process, exonucleolytic 6.519997e-3
GO:0008053 mitochondrial fusion 6.519997e-3
GO:0017183 peptidyl-diphthamide biosynthetic process from peptidyl-histidine 6.552426e-3
GO:0090305 nucleic acid phosphodiester bond hydrolysis 6.562765e-3
GO:0006450 regulation of translational fidelity 6.628837e-3
GO:0043153 entrainment of circadian clock by photoperiod 6.628837e-3
GO:0051586 positive regulation of dopamine uptake 6.628837e-3
GO:0021930 cerebellar granule cell precursor proliferation 6.628837e-3
GO:0007052 mitotic spindle organization 6.664959e-3
GO:0090292 nuclear matrix anchoring at nuclear membrane 6.728961e-3
GO:0021539 subthalamus development 6.728961e-3
GO:0035269 protein O-linked mannosylation 6.728961e-3
GO:0032069 regulation of nuclease activity 6.853802e-3
GO:0014009 glial cell proliferation 6.918772e-3
GO:0007031 peroxisome organization 6.978581e-3
GO:0010721 negative regulation of cell development 7.008057e-3
GO:0045987 positive regulation of smooth muscle contraction 7.129864e-3
GO:0060486 Clara cell differentiation 7.150446e-3
GO:0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 7.649421e-3
GO:0045906 negative regulation of vasoconstriction 7.649421e-3
GO:0016572 histone phosphorylation 7.658061e-3
GO:0002072 optic cup morphogenesis involved in camera-type eye development 7.841488e-3
GO:0060022 hard palate development 7.841488e-3
GO:0022037 metencephalon development 7.865428e-3
GO:0045792 negative regulation of cell size 7.936651e-3
GO:0034508 centromere complex assembly 7.936651e-3
GO:0006401 RNA catabolic process 7.958171e-3
GO:0032525 somite rostral/caudal axis specification 8.090832e-3
GO:0060972 left/right pattern formation 8.101137e-3
GO:0006303 double-strand break repair via nonhomologous end joining 8.101137e-3
GO:0072221 metanephric distal convoluted tubule development 8.138263e-3
GO:0061188 negative regulation of chromatin silencing at rDNA 8.317301e-3
GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein 8.329119e-3
GO:0016558 protein import into peroxisome matrix 8.393194e-3
GO:0007098 centrosome cycle 8.402720e-3
GO:0097029 mature dendritic cell differentiation 8.407507e-3
GO:2000001 regulation of DNA damage checkpoint 8.407507e-3
GO:0070368 positive regulation of hepatocyte differentiation 8.407507e-3
GO:0003273 cell migration involved in endocardial cushion formation 8.407507e-3
GO:2000078 positive regulation of type B pancreatic cell development 9.115809e-3
GO:0009648 photoperiodism 9.115809e-3
GO:0009082 branched chain family amino acid biosynthetic process 9.361286e-3
GO:0008050 female courtship behavior 9.586317e-3
GO:0046479 glycosphingolipid catabolic process 9.586317e-3
GO:0090336 positive regulation of brown fat cell differentiation 9.612440e-3
GO:0090271 positive regulation of fibroblast growth factor production 9.612440e-3
GO:0090362 positive regulation of platelet-derived growth factor production 9.612440e-3
GO:0006154 adenosine catabolic process 9.612440e-3
GO:0046103 inosine biosynthetic process 9.612440e-3
GO:0032431 activation of phospholipase A2 activity 9.612440e-3
GO:0097028 dendritic cell differentiation 9.654662e-3
GO:0035520 monoubiquitinated protein deubiquitination 9.654662e-3
GO:0000209 protein polyubiquitination 9.726266e-3
GO:0031109 microtubule polymerization or depolymerization 1.018299e-2
GO:0021860 pyramidal neuron development 1.018299e-2
GO:0003285 septum secundum development 1.045713e-2
GO:0006651 diacylglycerol biosynthetic process 1.045713e-2
GO:0043538 regulation of actin phosphorylation 1.058226e-2
GO:0015969 guanosine tetraphosphate metabolic process 1.058226e-2
GO:0090212 negative regulation of establishment of blood-brain barrier 1.058226e-2
GO:0014853 regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction 1.058226e-2
GO:0006666 3-keto-sphinganine metabolic process 1.058226e-2
GO:0009236 cobalamin biosynthetic process 1.058226e-2
GO:0061015 snRNA import into nucleus 1.076447e-2
GO:0035502 metanephric ureteric bud development 1.076447e-2
GO:0006683 galactosylceramide catabolic process 1.076447e-2
GO:0009443 pyridoxal 5'-phosphate salvage 1.076447e-2
GO:0017187 peptidyl-glutamic acid carboxylation 1.076447e-2
GO:0007059 chromosome segregation 1.112675e-2
GO:0032922 circadian regulation of gene expression 1.113881e-2
GO:0046827 positive regulation of protein export from nucleus 1.120537e-2
GO:0032774 RNA biosynthetic process 1.130317e-2
GO:0051313 attachment of spindle microtubules to chromosome 1.135221e-2
GO:0006390 transcription from mitochondrial promoter 1.135841e-2
GO:0048854 brain morphogenesis 1.139208e-2
GO:0003002 regionalization 1.146928e-2
GO:0072132 mesenchyme morphogenesis 1.184865e-2
GO:0070979 protein K11-linked ubiquitination 1.203878e-2
GO:0006269 DNA replication, synthesis of RNA primer 1.215815e-2
GO:0021568 rhombomere 2 development 1.215815e-2
GO:0001840 neural plate development 1.217394e-2
GO:0032202 telomere assembly 1.223636e-2
GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c 1.223636e-2
GO:0072044 collecting duct development 1.236207e-2
GO:0006105 succinate metabolic process 1.241539e-2
GO:0060044 negative regulation of cardiac muscle cell proliferation 1.246249e-2
GO:0048793 pronephros development 1.257080e-2
GO:0050768 negative regulation of neurogenesis 1.259519e-2
GO:0006351 transcription, DNA-dependent 1.275333e-2
GO:0032331 negative regulation of chondrocyte differentiation 1.291486e-2
GO:0031323 regulation of cellular metabolic process 1.295081e-2
GO:0072182 regulation of nephron tubule epithelial cell differentiation 1.308627e-2
GO:0003323 type B pancreatic cell development 1.329520e-2
GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway 1.340913e-2
GO:0046092 deoxycytidine metabolic process 1.340913e-2
GO:0034498 early endosome to Golgi transport 1.340913e-2
GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response 1.340913e-2
GO:0032608 interferon-beta production 1.340913e-2
GO:0072488 ammonium transmembrane transport 1.345582e-2
GO:0071585 detoxification of cadmium ion 1.359603e-2
GO:2000615 regulation of histone H3-K9 acetylation 1.359603e-2
GO:0071539 protein localization to centrosome 1.359603e-2
GO:0060809 mesodermal to mesenchymal transition involved in gastrulation 1.359603e-2
GO:0006807 nitrogen compound metabolic process 1.365627e-2
GO:0006264 mitochondrial DNA replication 1.367004e-2
GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus 1.404768e-2
GO:0003290 atrial septum secundum morphogenesis 1.404768e-2
GO:0070845 polyubiquitinated misfolded protein transport 1.408769e-2
GO:0061301 cerebellum vasculature morphogenesis 1.408769e-2
GO:2000778 positive regulation of interleukin-6 secretion 1.408769e-2
GO:0030421 defecation 1.408769e-2
GO:0032074 negative regulation of nuclease activity 1.408769e-2
GO:0051466 positive regulation of corticotropin-releasing hormone secretion 1.408769e-2
GO:0071845 cellular component disassembly at cellular level 1.414816e-2
GO:0031018 endocrine pancreas development 1.450233e-2
GO:0060430 lung saccule development 1.457871e-2
GO:0001707 mesoderm formation 1.476123e-2
GO:0003272 endocardial cushion formation 1.519560e-2
GO:0090381 regulation of heart induction 1.523278e-2
GO:0090361 regulation of platelet-derived growth factor production 1.523278e-2
GO:0019673 GDP-mannose metabolic process 1.523278e-2
GO:0001832 blastocyst growth 1.553743e-2
GO:0033365 protein localization to organelle 1.556589e-2
GO:0000819 sister chromatid segregation 1.578983e-2
GO:0035434 copper ion transmembrane transport 1.588838e-2
GO:0032446 protein modification by small protein conjugation 1.589549e-2
GO:0072054 renal outer medulla development 1.593327e-2
GO:0046620 regulation of organ growth 1.606459e-2
GO:0070842 aggresome assembly 1.607403e-2
GO:0030422 production of siRNA involved in RNA interference 1.607403e-2
GO:0043985 histone H4-R3 methylation 1.607403e-2
GO:0042424 catecholamine catabolic process 1.626677e-2
GO:0061205 paramesonephric duct development 1.626677e-2
GO:0006116 NADH oxidation 1.626677e-2
GO:0055118 negative regulation of cardiac muscle contraction 1.632577e-2
GO:0050774 negative regulation of dendrite morphogenesis 1.632577e-2
GO:0051303 establishment of chromosome localization 1.652721e-2
GO:0051171 regulation of nitrogen compound metabolic process 1.652974e-2
GO:0071285 cellular response to lithium ion 1.654207e-2
GO:0034645 cellular macromolecule biosynthetic process 1.656345e-2
GO:0007093 mitotic cell cycle checkpoint 1.701626e-2
GO:0042119 neutrophil activation 1.724016e-2
GO:0070918 production of small RNA involved in gene silencing by RNA 1.744014e-2
GO:0021527 spinal cord association neuron differentiation 1.748014e-2
GO:0035054 embryonic heart tube anterior/posterior pattern specification 1.781353e-2
GO:0002065 columnar/cuboidal epithelial cell differentiation 1.781931e-2
GO:0072197 ureter morphogenesis 1.795030e-2
GO:0072076 nephrogenic mesenchyme development 1.810359e-2
GO:0043697 cell dedifferentiation 1.810359e-2
GO:0072177 mesonephric duct development 1.811331e-2
GO:0016180 snRNA processing 1.811331e-2
GO:0046784 intronless viral mRNA export from host nucleus 1.811331e-2
GO:0022411 cellular component disassembly 1.842529e-2
GO:0060433 bronchus development 1.846993e-2
GO:0045750 positive regulation of S phase of mitotic cell cycle 1.853047e-2
GO:0019219 regulation of nucleobase-containing compound metabolic process 1.856553e-2
GO:0007051 spindle organization 1.863039e-2
GO:0032006 regulation of TOR signaling cascade 1.867098e-2
GO:0051542 elastin biosynthetic process 1.875899e-2
GO:2000256 positive regulation of male germ cell proliferation 1.875899e-2
GO:0045900 negative regulation of translational elongation 1.875899e-2
GO:0048553 negative regulation of metalloenzyme activity 1.875899e-2
GO:0006258 UDP-glucose catabolic process 1.875899e-2
GO:0006844 acyl carnitine transport 1.875899e-2
GO:0042231 interleukin-13 biosynthetic process 1.875899e-2
GO:0051204 protein insertion into mitochondrial membrane 1.884959e-2
GO:0044338 canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation 1.884959e-2
GO:0044339 canonical Wnt receptor signaling pathway involved in osteoblast differentiation 1.884959e-2
GO:0006354 transcription elongation, DNA-dependent 1.899066e-2
GO:0000959 mitochondrial RNA metabolic process 1.901322e-2
GO:0071824 protein-DNA complex subunit organization 1.909575e-2
GO:0048384 retinoic acid receptor signaling pathway 1.914686e-2
GO:0030889 negative regulation of B cell proliferation 1.928064e-2
GO:0034501 protein localization to kinetochore 1.935518e-2
GO:0055119 relaxation of cardiac muscle 1.936462e-2
GO:0042524 negative regulation of tyrosine phosphorylation of Stat5 protein 1.936462e-2
GO:0051865 protein autoubiquitination 1.944159e-2
GO:0072053 renal inner medulla development 1.949828e-2
GO:0035329 hippo signaling cascade 1.967124e-2
GO:0050684 regulation of mRNA processing 1.980600e-2
GO:0006931 substrate-dependent cell migration, cell attachment to substrate 1.983062e-2
GO:0033084 regulation of immature T cell proliferation in thymus 1.985932e-2
GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening 1.985932e-2
GO:0001839 neural plate morphogenesis 1.985932e-2
GO:0007369 gastrulation 1.991789e-2
GO:0090184 positive regulation of kidney development 2.028450e-2
GO:0015812 gamma-aminobutyric acid transport 2.054356e-2
GO:0046602 regulation of mitotic centrosome separation 2.057131e-2
GO:0090035 positive regulation of cellular chaperone-mediated protein complex assembly 2.057131e-2
GO:0018192 enzyme active site formation via L-cysteine persulfide 2.057131e-2
GO:0000917 barrier septum formation 2.057131e-2
GO:0090072 positive regulation of sodium ion transport via voltage-gated sodium channel activity 2.070912e-2
GO:0043491 protein kinase B signaling cascade 2.078985e-2
GO:0051168 nuclear export 2.087004e-2
GO:0042796 snRNA transcription from RNA polymerase III promoter 2.088604e-2
GO:2000002 negative regulation of DNA damage checkpoint 2.088604e-2
GO:0042795 snRNA transcription from RNA polymerase II promoter 2.088604e-2
GO:0021588 cerebellum formation 2.088604e-2
GO:0022004 midbrain-hindbrain boundary maturation during brain development 2.088604e-2