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Novel motif:112

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name:motif112_CGYGYAWT

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0000236 mitotic prometaphase 2.199433e-14
GO:0022402 cell cycle process 1.638689e-10
GO:0022403 cell cycle phase 1.704789e-10
GO:0065003 macromolecular complex assembly 3.051985e-10
GO:0000278 mitotic cell cycle 6.138118e-10
GO:0000279 M phase 1.018863e-9
GO:0008210 estrogen metabolic process 5.487582e-9
GO:0007051 spindle organization 6.600534e-9
GO:0021520 spinal cord motor neuron cell fate specification 9.166912e-9
GO:0000087 M phase of mitotic cell cycle 1.023016e-8
GO:0035272 exocrine system development 3.321233e-8
GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching 6.912395e-8
GO:0030953 astral microtubule organization 7.932789e-8
GO:0043933 macromolecular complex subunit organization 9.245866e-8
GO:0007067 mitosis 1.033481e-7
GO:0051256 spindle midzone assembly involved in mitosis 1.089079e-7
GO:0034622 cellular macromolecular complex assembly 1.522304e-7
GO:0090031 positive regulation of steroid hormone biosynthetic process 1.567556e-7
GO:0034080 CenH3-containing nucleosome assembly at centromere 2.062213e-7
GO:0009235 cobalamin metabolic process 2.103394e-7
GO:0046628 positive regulation of insulin receptor signaling pathway 2.475574e-7
GO:0071822 protein complex subunit organization 2.673409e-7
GO:0007052 mitotic spindle organization 3.633446e-7
GO:0048285 organelle fission 3.705880e-7
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 4.512561e-7
GO:0006461 protein complex assembly 4.618270e-7
GO:0031017 exocrine pancreas development 4.757169e-7
GO:0070271 protein complex biogenesis 4.913039e-7
GO:0001501 skeletal system development 5.443319e-7
GO:0008209 androgen metabolic process 5.492712e-7
GO:0046886 positive regulation of hormone biosynthetic process 6.612938e-7
GO:0016191 synaptic vesicle uncoating 7.152992e-7
GO:0007049 cell cycle 7.478060e-7
GO:2000467 positive regulation of glycogen (starch) synthase activity 7.743113e-7
GO:0010631 epithelial cell migration 7.858490e-7
GO:0051365 cellular response to potassium ion starvation 8.483838e-7
GO:0060600 dichotomous subdivision of an epithelial terminal unit 8.617415e-7
GO:0034619 cellular chaperone-mediated protein complex assembly 1.029636e-6
GO:0001830 trophectodermal cell fate commitment 1.199856e-6
GO:0035026 leading edge cell differentiation 1.404379e-6
GO:2000465 regulation of glycogen (starch) synthase activity 1.479969e-6
GO:0019046 reactivation of latent virus 1.928983e-6
GO:0031055 chromatin remodeling at centromere 2.029028e-6
GO:0006396 RNA processing 2.512215e-6
GO:0022618 ribonucleoprotein complex assembly 3.170550e-6
GO:0071526 semaphorin-plexin signaling pathway 3.495285e-6
GO:0050853 B cell receptor signaling pathway 3.511668e-6
GO:0071826 ribonucleoprotein complex subunit organization 3.769844e-6
GO:0001923 B-1 B cell differentiation 4.202551e-6
GO:0051261 protein depolymerization 4.844839e-6
GO:0035129 post-embryonic hindlimb morphogenesis 5.048874e-6
GO:0034621 cellular macromolecular complex subunit organization 5.727601e-6
GO:0009650 UV protection 6.711889e-6
GO:0045081 negative regulation of interleukin-10 biosynthetic process 6.798165e-6
GO:0009744 response to sucrose stimulus 6.976413e-6
GO:0046339 diacylglycerol metabolic process 7.695087e-6
GO:0090130 tissue migration 8.860766e-6
GO:0016339 calcium-dependent cell-cell adhesion 9.266144e-6
GO:0045040 protein import into mitochondrial outer membrane 9.951039e-6
GO:0090307 spindle assembly involved in mitosis 1.045661e-5
GO:0009437 carnitine metabolic process 1.507674e-5
GO:0000718 nucleotide-excision repair, DNA damage removal 1.654651e-5
GO:0051255 spindle midzone assembly 1.779873e-5
GO:0051260 protein homooligomerization 1.837333e-5
GO:0006428 isoleucyl-tRNA aminoacylation 1.839754e-5
GO:0048266 behavioral response to pain 1.968378e-5
GO:0001732 formation of translation initiation complex 2.208430e-5
GO:0022613 ribonucleoprotein complex biogenesis 2.264494e-5
GO:0071391 cellular response to estrogen stimulus 2.296353e-5
GO:0006471 protein ADP-ribosylation 2.396910e-5
GO:0001649 osteoblast differentiation 2.476162e-5
GO:0006289 nucleotide-excision repair 2.495066e-5
GO:0043486 histone exchange 2.508739e-5
GO:0090231 regulation of spindle checkpoint 2.654898e-5
GO:0044085 cellular component biogenesis 2.836548e-5
GO:0006354 transcription elongation, DNA-dependent 2.914873e-5
GO:0000226 microtubule cytoskeleton organization 3.449809e-5
GO:0033365 protein localization to organelle 3.578824e-5
GO:0022607 cellular component assembly 3.690834e-5
GO:0006283 transcription-coupled nucleotide-excision repair 3.958505e-5
GO:0031122 cytoplasmic microtubule organization 4.193846e-5
GO:0001503 ossification 4.423623e-5
GO:0002176 male germ cell proliferation 4.931769e-5
GO:0046885 regulation of hormone biosynthetic process 4.998860e-5
GO:0022027 interkinetic nuclear migration 5.012357e-5
GO:0090030 regulation of steroid hormone biosynthetic process 5.323479e-5
GO:0007606 sensory perception of chemical stimulus 5.640823e-5
GO:0043044 ATP-dependent chromatin remodeling 5.689483e-5
GO:0030187 melatonin biosynthetic process 5.814497e-5
GO:0046856 phosphatidylinositol dephosphorylation 6.032393e-5
GO:0051298 centrosome duplication 6.328898e-5
GO:0006397 mRNA processing 7.018482e-5
GO:0060445 branching involved in salivary gland morphogenesis 7.195519e-5
GO:0045074 regulation of interleukin-10 biosynthetic process 7.473503e-5
GO:0071514 genetic imprinting 7.485121e-5
GO:0048665 neuron fate specification 7.513294e-5
GO:0006368 transcription elongation from RNA polymerase II promoter 7.634815e-5
GO:0001708 cell fate specification 8.056701e-5
GO:0042026 protein refolding 8.322642e-5
GO:0090232 positive regulation of spindle checkpoint 8.445790e-5
GO:0044265 cellular macromolecule catabolic process 8.462834e-5
GO:0033205 cell cycle cytokinesis 8.547319e-5
GO:0050930 induction of positive chemotaxis 8.675996e-5
GO:0070286 axonemal dynein complex assembly 9.089551e-5
GO:0032472 Golgi calcium ion transport 9.089551e-5
GO:0032468 Golgi calcium ion homeostasis 9.089551e-5
GO:0030026 cellular manganese ion homeostasis 9.089551e-5
GO:0051301 cell division 1.019743e-4
GO:0016476 regulation of embryonic cell shape 1.058714e-4
GO:0009112 nucleobase metabolic process 1.065031e-4
GO:0033327 Leydig cell differentiation 1.117302e-4
GO:0021918 regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment 1.214472e-4
GO:0021905 forebrain-midbrain boundary formation 1.214472e-4
GO:0003322 pancreatic A cell development 1.214472e-4
GO:0021902 commitment of neuronal cell to specific neuron type in forebrain 1.214472e-4
GO:0030186 melatonin metabolic process 1.252913e-4
GO:0032352 positive regulation of hormone metabolic process 1.265927e-4
GO:0032332 positive regulation of chondrocyte differentiation 1.280880e-4
GO:0051865 protein autoubiquitination 1.283099e-4
GO:0071109 superior temporal gyrus development 1.290924e-4
GO:0071843 cellular component biogenesis at cellular level 1.364247e-4
GO:0071816 tail-anchored membrane protein insertion into ER membrane 1.379775e-4
GO:0090346 cellular organofluorine metabolic process 1.430764e-4
GO:0043602 nitrate catabolic process 1.430764e-4
GO:0046210 nitric oxide catabolic process 1.430764e-4
GO:0051781 positive regulation of cell division 1.468339e-4
GO:0060119 inner ear receptor cell development 1.656647e-4
GO:0006363 termination of RNA polymerase I transcription 1.668017e-4
GO:0021978 telencephalon regionalization 1.880123e-4
GO:0010988 regulation of low-density lipoprotein particle clearance 1.884000e-4
GO:0046121 deoxyribonucleoside catabolic process 2.057297e-4
GO:0070562 regulation of vitamin D receptor signaling pathway 2.256368e-4
GO:0048008 platelet-derived growth factor receptor signaling pathway 2.266493e-4
GO:0003350 pulmonary myocardium development 2.338428e-4
GO:0071777 positive regulation of cell cycle cytokinesis 2.355282e-4
GO:0007435 salivary gland morphogenesis 2.381737e-4
GO:0061035 regulation of cartilage development 2.406696e-4
GO:0021522 spinal cord motor neuron differentiation 2.445047e-4
GO:0033345 asparagine catabolic process via L-aspartate 2.467941e-4
GO:0006271 DNA strand elongation involved in DNA replication 2.497505e-4
GO:0048705 skeletal system morphogenesis 2.529804e-4
GO:0009953 dorsal/ventral pattern formation 2.547732e-4
GO:0010467 gene expression 2.566919e-4
GO:0060606 tube closure 2.596482e-4
GO:0051668 localization within membrane 2.618064e-4
GO:0070914 UV-damage excision repair 2.631292e-4
GO:0035284 brain segmentation 2.651567e-4
GO:0048935 peripheral nervous system neuron development 2.764934e-4
GO:0032330 regulation of chondrocyte differentiation 2.848336e-4
GO:0009992 cellular water homeostasis 2.851172e-4
GO:0010893 positive regulation of steroid biosynthetic process 2.940134e-4
GO:0006839 mitochondrial transport 2.947623e-4
GO:0034661 ncRNA catabolic process 3.013478e-4
GO:0035094 response to nicotine 3.017187e-4
GO:0001843 neural tube closure 3.023906e-4
GO:0006412 translation 3.069916e-4
GO:0009057 macromolecule catabolic process 3.126837e-4
GO:0002448 mast cell mediated immunity 3.316772e-4
GO:0008615 pyridoxine biosynthetic process 3.326963e-4
GO:0032808 lacrimal gland development 3.336005e-4
GO:0009452 RNA capping 3.463022e-4
GO:0006607 NLS-bearing substrate import into nucleus 3.482054e-4
GO:0001667 ameboidal cell migration 3.815548e-4
GO:0050916 sensory perception of sweet taste 3.859649e-4
GO:0009264 deoxyribonucleotide catabolic process 3.953416e-4
GO:0032802 low-density lipoprotein particle receptor catabolic process 4.109684e-4
GO:0006353 transcription termination, DNA-dependent 4.120405e-4
GO:0021532 neural tube patterning 4.151352e-4
GO:0048839 inner ear development 4.570540e-4
GO:0045636 positive regulation of melanocyte differentiation 4.586374e-4
GO:0007431 salivary gland development 4.715776e-4
GO:0014020 primary neural tube formation 4.851338e-4
GO:0007608 sensory perception of smell 4.878273e-4
GO:0070925 organelle assembly 4.890937e-4
GO:0006362 transcription elongation from RNA polymerase I promoter 4.891018e-4
GO:0009110 vitamin biosynthetic process 4.891018e-4
GO:0045556 positive regulation of TRAIL biosynthetic process 5.003683e-4
GO:0031645 negative regulation of neurological system process 5.128306e-4
GO:0050926 regulation of positive chemotaxis 5.463514e-4
GO:0045669 positive regulation of osteoblast differentiation 5.486426e-4
GO:2000369 regulation of clathrin-mediated endocytosis 5.587248e-4
GO:0051225 spindle assembly 5.615439e-4
GO:0051205 protein insertion into membrane 5.615715e-4
GO:0060560 developmental growth involved in morphogenesis 5.720975e-4
GO:0050907 detection of chemical stimulus involved in sensory perception 5.738022e-4
GO:0021987 cerebral cortex development 5.782038e-4
GO:0043467 regulation of generation of precursor metabolites and energy 5.885814e-4
GO:0044260 cellular macromolecule metabolic process 5.892587e-4
GO:0021615 glossopharyngeal nerve morphogenesis 5.995782e-4
GO:0006413 translational initiation 6.133255e-4
GO:0060113 inner ear receptor cell differentiation 6.146674e-4
GO:0051970 negative regulation of transmission of nerve impulse 6.196128e-4
GO:0050911 detection of chemical stimulus involved in sensory perception of smell 6.220492e-4
GO:0030853 negative regulation of granulocyte differentiation 6.243255e-4
GO:0010739 positive regulation of protein kinase A signaling cascade 6.307978e-4
GO:0022616 DNA strand elongation 6.324725e-4
GO:0051898 negative regulation of protein kinase B signaling cascade 6.324725e-4
GO:0007342 fusion of sperm to egg plasma membrane 6.331451e-4
GO:0006370 mRNA capping 6.516371e-4
GO:0002536 respiratory burst involved in inflammatory response 6.727776e-4
GO:0007422 peripheral nervous system development 6.799191e-4
GO:0045023 G0 to G1 transition 7.278158e-4
GO:0010917 negative regulation of mitochondrial membrane potential 7.278158e-4
GO:0050927 positive regulation of positive chemotaxis 7.372204e-4
GO:0050857 positive regulation of antigen receptor-mediated signaling pathway 7.654380e-4
GO:0006139 nucleobase-containing compound metabolic process 7.743387e-4
GO:0050805 negative regulation of synaptic transmission 7.971439e-4
GO:0009648 photoperiodism 8.249613e-4
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion 8.249613e-4
GO:0002076 osteoblast development 8.786980e-4
GO:0006361 transcription initiation from RNA polymerase I promoter 8.939572e-4
GO:0061303 cornea development in camera-type eye 8.948930e-4
GO:0009267 cellular response to starvation 9.041562e-4
GO:0071034 CUT catabolic process 9.194181e-4
GO:0046113 nucleobase catabolic process 9.234126e-4
GO:0051325 interphase 9.272587e-4
GO:0060028 convergent extension involved in axis elongation 9.315404e-4
GO:0002021 response to dietary excess 9.319539e-4
GO:0048385 regulation of retinoic acid receptor signaling pathway 9.319904e-4
GO:0090304 nucleic acid metabolic process 9.599368e-4
GO:0001915 negative regulation of T cell mediated cytotoxicity 9.688065e-4
GO:0006208 pyrimidine base catabolic process 9.891335e-4
GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway 9.909901e-4
GO:0072285 mesenchymal to epithelial transition involved in metanephric renal vesicle formation 9.909901e-4
GO:0060248 detection of cell density by contact stimulus involved in contact inhibition 9.909901e-4
GO:0042840 D-glucuronate catabolic process 9.909901e-4
GO:0007371 ventral midline determination 9.909901e-4
GO:0016071 mRNA metabolic process 1.011614e-3
GO:0048260 positive regulation of receptor-mediated endocytosis 1.042383e-3
GO:0032467 positive regulation of cytokinesis 1.043659e-3
GO:0015889 cobalamin transport 1.054521e-3
GO:0048755 branching morphogenesis of a nerve 1.114756e-3
GO:0021658 rhombomere 3 morphogenesis 1.117137e-3
GO:0021796 cerebral cortex regionalization 1.136239e-3
GO:0048663 neuron fate commitment 1.136487e-3
GO:0034199 activation of protein kinase A activity 1.138868e-3
GO:0048675 axon extension 1.247661e-3
GO:0003151 outflow tract morphogenesis 1.250977e-3
GO:0008152 metabolic process 1.268680e-3
GO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis 1.270155e-3
GO:0006853 carnitine shuttle 1.270155e-3
GO:0051131 chaperone-mediated protein complex assembly 1.273599e-3
GO:0046839 phospholipid dephosphorylation 1.279302e-3
GO:0051329 interphase of mitotic cell cycle 1.279714e-3
GO:0051302 regulation of cell division 1.300862e-3
GO:0033081 regulation of T cell differentiation in thymus 1.325274e-3
GO:0000720 pyrimidine dimer repair by nucleotide-excision repair 1.330521e-3
GO:0032971 regulation of muscle filament sliding 1.333804e-3
GO:0070207 protein homotrimerization 1.360360e-3
GO:0000387 spliceosomal snRNP assembly 1.360456e-3
GO:0072655 establishment of protein localization in mitochondrion 1.360816e-3
GO:0031953 negative regulation of protein autophosphorylation 1.361393e-3
GO:0009129 pyrimidine nucleoside monophosphate metabolic process 1.363419e-3
GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway 1.416664e-3
GO:0006206 pyrimidine base metabolic process 1.455792e-3
GO:0060592 mammary gland formation 1.469597e-3
GO:0019852 L-ascorbic acid metabolic process 1.496415e-3
GO:0045634 regulation of melanocyte differentiation 1.526322e-3
GO:0001514 selenocysteine incorporation 1.556357e-3
GO:0009058 biosynthetic process 1.557483e-3
GO:0071157 negative regulation of cell cycle arrest 1.569730e-3
GO:0045906 negative regulation of vasoconstriction 1.569730e-3
GO:0048588 developmental cell growth 1.582055e-3
GO:0019853 L-ascorbic acid biosynthetic process 1.589976e-3
GO:0060174 limb bud formation 1.615084e-3
GO:0007017 microtubule-based process 1.640586e-3
GO:0002444 myeloid leukocyte mediated immunity 1.685486e-3
GO:0060594 mammary gland specification 1.695905e-3
GO:0034754 cellular hormone metabolic process 1.716758e-3
GO:0019228 regulation of action potential in neuron 1.720137e-3
GO:0001704 formation of primary germ layer 1.743548e-3
GO:0048311 mitochondrion distribution 1.765371e-3
GO:0046889 positive regulation of lipid biosynthetic process 1.771596e-3
GO:0021602 cranial nerve morphogenesis 1.773263e-3
GO:0046716 muscle cell homeostasis 1.815702e-3
GO:0048646 anatomical structure formation involved in morphogenesis 1.844863e-3
GO:0000090 mitotic anaphase 1.857631e-3
GO:0050917 sensory perception of umami taste 1.864212e-3
GO:0001662 behavioral fear response 1.887446e-3
GO:0021915 neural tube development 1.898779e-3
GO:0009446 putrescine biosynthetic process 1.911876e-3
GO:0006382 adenosine to inosine editing 1.987455e-3
GO:0044237 cellular metabolic process 1.991345e-3
GO:0001825 blastocyst formation 2.003287e-3
GO:2000253 positive regulation of feeding behavior 2.006104e-3
GO:2000507 positive regulation of energy homeostasis 2.006104e-3
GO:0050906 detection of stimulus involved in sensory perception 2.029874e-3
GO:0070585 protein localization in mitochondrion 2.105220e-3
GO:0048087 positive regulation of developmental pigmentation 2.110569e-3
GO:0006349 regulation of gene expression by genetic imprinting 2.157109e-3
GO:0000245 spliceosome assembly 2.202688e-3
GO:0021543 pallium development 2.210066e-3
GO:0055078 sodium ion homeostasis 2.221716e-3
GO:0006913 nucleocytoplasmic transport 2.292055e-3
GO:0030913 paranodal junction assembly 2.294586e-3
GO:0042249 establishment of planar polarity of embryonic epithelium 2.294586e-3
GO:0000710 meiotic mismatch repair 2.294586e-3
GO:0002209 behavioral defense response 2.325828e-3
GO:0000724 double-strand break repair via homologous recombination 2.362326e-3
GO:0006974 response to DNA damage stimulus 2.395520e-3
GO:0017038 protein import 2.464961e-3
GO:0050910 detection of mechanical stimulus involved in sensory perception of sound 2.496063e-3
GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion 2.505857e-3
GO:0031023 microtubule organizing center organization 2.507195e-3
GO:0001553 luteinization 2.539357e-3
GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process 2.555433e-3
GO:0042364 water-soluble vitamin biosynthetic process 2.557750e-3
GO:0010608 posttranscriptional regulation of gene expression 2.589756e-3
GO:0023019 signal transduction involved in regulation of gene expression 2.628613e-3
GO:0048146 positive regulation of fibroblast proliferation 2.644538e-3
GO:0071841 cellular component organization or biogenesis at cellular level 2.713337e-3
GO:0032288 myelin assembly 2.716229e-3
GO:0002378 immunoglobulin biosynthetic process 2.767072e-3
GO:0000725 recombinational repair 2.813431e-3
GO:0016075 rRNA catabolic process 2.818809e-3
GO:0048496 maintenance of organ identity 2.818809e-3
GO:0050434 positive regulation of viral transcription 2.820825e-3
GO:0048265 response to pain 2.848653e-3
GO:0034504 protein localization to nucleus 2.897436e-3
GO:0015879 carnitine transport 2.905578e-3
GO:0031016 pancreas development 2.922393e-3
GO:0010907 positive regulation of glucose metabolic process 2.926505e-3
GO:0042490 mechanoreceptor differentiation 2.955151e-3
GO:0006446 regulation of translational initiation 2.962050e-3
GO:0045940 positive regulation of steroid metabolic process 2.977415e-3
GO:0002051 osteoblast fate commitment 2.996148e-3
GO:0000022 mitotic spindle elongation 2.996148e-3
GO:0043088 regulation of Cdc42 GTPase activity 2.998091e-3
GO:0010984 regulation of lipoprotein particle clearance 3.026926e-3
GO:0031123 RNA 3'-end processing 3.039341e-3
GO:0034660 ncRNA metabolic process 3.052871e-3
GO:0031018 endocrine pancreas development 3.055689e-3
GO:0000375 RNA splicing, via transesterification reactions 3.072327e-3
GO:0045667 regulation of osteoblast differentiation 3.094392e-3
GO:0042321 negative regulation of circadian sleep/wake cycle, sleep 3.110311e-3
GO:0007019 microtubule depolymerization 3.125977e-3
GO:0051647 nucleus localization 3.137530e-3
GO:0006308 DNA catabolic process 3.189444e-3
GO:0043170 macromolecule metabolic process 3.197041e-3
GO:0090251 protein localization involved in establishment of planar polarity 3.198214e-3
GO:0021798 forebrain dorsal/ventral pattern formation 3.227707e-3
GO:0042780 tRNA 3'-end processing 3.227736e-3
GO:2000323 negative regulation of glucocorticoid receptor signaling pathway 3.227736e-3
GO:0010571 positive regulation of DNA replication involved in S phase 3.227736e-3
GO:0000281 cytokinesis after mitosis 3.341440e-3
GO:0043633 polyadenylation-dependent RNA catabolic process 3.356361e-3
GO:0051169 nuclear transport 3.382234e-3
GO:0050913 sensory perception of bitter taste 3.385924e-3
GO:0035499 carnosine biosynthetic process 3.444040e-3
GO:0060668 regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling 3.444040e-3
GO:0008380 RNA splicing 3.486940e-3
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity 3.494814e-3
GO:0001911 negative regulation of leukocyte mediated cytotoxicity 3.494814e-3
GO:0007043 cell-cell junction assembly 3.500342e-3
GO:0043623 cellular protein complex assembly 3.559935e-3
GO:0033683 nucleotide-excision repair, DNA incision 3.561081e-3
GO:0003096 renal sodium ion transport 3.561081e-3
GO:2000505 regulation of energy homeostasis 3.584938e-3
GO:0021846 cell proliferation in forebrain 3.589619e-3
GO:0015872 dopamine transport 3.617311e-3
GO:0042596 fear response 3.663139e-3
GO:0043103 hypoxanthine salvage 3.762146e-3
GO:0071205 protein localization to juxtaparanode region of axon 3.762146e-3
GO:0031573 intra-S DNA damage checkpoint 3.762146e-3
GO:0032803 regulation of low-density lipoprotein particle receptor catabolic process 3.762146e-3
GO:0006473 protein acetylation 3.773919e-3
GO:0060348 bone development 3.783249e-3
GO:0033962 cytoplasmic mRNA processing body assembly 3.823406e-3
GO:0000398 nuclear mRNA splicing, via spliceosome 3.867116e-3
GO:0006517 protein deglycosylation 3.928666e-3
GO:0007600 sensory perception 4.017197e-3
GO:0034641 cellular nitrogen compound metabolic process 4.175265e-3
GO:0008633 activation of pro-apoptotic gene products 4.196937e-3
GO:0006435 threonyl-tRNA aminoacylation 4.222609e-3
GO:0006290 pyrimidine dimer repair 4.222609e-3
GO:0006772 thiamine metabolic process 4.275808e-3
GO:0032465 regulation of cytokinesis 4.278198e-3
GO:0042074 cell migration involved in gastrulation 4.319367e-3
GO:0009163 nucleoside biosynthetic process 4.346107e-3
GO:0001508 regulation of action potential 4.370280e-3
GO:0030104 water homeostasis 4.374410e-3
GO:0033555 multicellular organismal response to stress 4.445347e-3
GO:0051303 establishment of chromosome localization 4.484994e-3
GO:0030282 bone mineralization 4.528203e-3
GO:0060523 prostate epithelial cord elongation 4.586373e-3
GO:0030163 protein catabolic process 4.595715e-3
GO:2000179 positive regulation of neural precursor cell proliferation 4.635576e-3
GO:0016072 rRNA metabolic process 4.693571e-3
GO:0000093 mitotic telophase 4.725223e-3
GO:0010738 regulation of protein kinase A signaling cascade 4.735888e-3
GO:2001108 positive regulation of Rho guanyl-nucleotide exchange factor activity 4.770995e-3
GO:0003420 regulation of growth plate cartilage chondrocyte proliferation 4.770995e-3
GO:0044249 cellular biosynthetic process 4.808303e-3
GO:0006422 aspartyl-tRNA aminoacylation 4.848233e-3
GO:0071842 cellular component organization at cellular level 4.884495e-3
GO:0006626 protein targeting to mitochondrion 4.941933e-3
GO:0006154 adenosine catabolic process 4.990381e-3
GO:0046103 inosine biosynthetic process 4.990381e-3
GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling 5.047260e-3
GO:0031342 negative regulation of cell killing 5.058474e-3
GO:0006401 RNA catabolic process 5.066567e-3
GO:0048387 negative regulation of retinoic acid receptor signaling pathway 5.116028e-3
GO:0031647 regulation of protein stability 5.173744e-3
GO:0030030 cell projection organization 5.221260e-3
GO:0009130 pyrimidine nucleoside monophosphate biosynthetic process 5.272162e-3
GO:0006334 nucleosome assembly 5.287046e-3
GO:0030854 positive regulation of granulocyte differentiation 5.346266e-3
GO:0045026 plasma membrane fusion 5.384343e-3
GO:0015886 heme transport 5.399183e-3
GO:0065004 protein-DNA complex assembly 5.417376e-3
GO:0006312 mitotic recombination 5.537074e-3
GO:0006360 transcription from RNA polymerase I promoter 5.563635e-3
GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness 5.620183e-3
GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter 5.649372e-3
GO:0021957 corticospinal tract morphogenesis 5.649372e-3
GO:0006475 internal protein amino acid acetylation 5.695578e-3
GO:0021903 rostrocaudal neural tube patterning 5.718784e-3
GO:0006222 UMP biosynthetic process 5.792315e-3
GO:0060003 copper ion export 5.804269e-3
GO:0015677 copper ion import 5.804269e-3
GO:0008295 spermidine biosynthetic process 5.804269e-3
GO:0043525 positive regulation of neuron apoptosis 5.820684e-3
GO:0060687 regulation of branching involved in prostate gland morphogenesis 5.849362e-3
GO:0043558 regulation of translational initiation in response to stress 5.866675e-3
GO:0035166 post-embryonic hemopoiesis 5.866675e-3
GO:0072104 glomerular capillary formation 5.883426e-3
GO:0060349 bone morphogenesis 5.929365e-3
GO:0043583 ear development 5.980133e-3
GO:0000089 mitotic metaphase 6.055168e-3
GO:0008635 activation of caspase activity by cytochrome c 6.055168e-3
GO:0071844 cellular component assembly at cellular level 6.146226e-3
GO:0032319 regulation of Rho GTPase activity 6.218846e-3
GO:0045880 positive regulation of smoothened signaling pathway 6.253787e-3
GO:0030852 regulation of granulocyte differentiation 6.274496e-3
GO:0006996 organelle organization 6.415904e-3
GO:0045759 negative regulation of action potential 6.478116e-3
GO:0019254 carnitine metabolic process, CoA-linked 6.478116e-3
GO:0051322 anaphase 6.484945e-3
GO:0000027 ribosomal large subunit assembly 6.529321e-3
GO:0051297 centrosome organization 6.541680e-3
GO:0040001 establishment of mitotic spindle localization 6.918393e-3
GO:0009414 response to water deprivation 6.952869e-3
GO:2000273 positive regulation of receptor activity 7.013085e-3
GO:0010165 response to X-ray 7.071337e-3
GO:0060350 endochondral bone morphogenesis 7.196862e-3
GO:0035646 endosome to melanosome transport 7.211586e-3
GO:0001920 negative regulation of receptor recycling 7.211586e-3
GO:0033262 regulation of DNA replication involved in S phase 7.211586e-3
GO:0060259 regulation of feeding behavior 7.242796e-3
GO:0001841 neural tube formation 7.246672e-3
GO:0016049 cell growth 7.316205e-3
GO:0016553 base conversion or substitution editing 7.541029e-3
GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning 7.541682e-3
GO:0010906 regulation of glucose metabolic process 7.910026e-3
GO:0051641 cellular localization 7.910339e-3
GO:0042819 vitamin B6 biosynthetic process 7.956745e-3
GO:0006556 S-adenosylmethionine biosynthetic process 7.956745e-3
GO:0032321 positive regulation of Rho GTPase activity 7.983211e-3
GO:0021636 trigeminal nerve morphogenesis 8.232903e-3
GO:0051457 maintenance of protein location in nucleus 8.266707e-3
GO:0000086 G2/M transition of mitotic cell cycle 8.416481e-3
GO:0061072 iris morphogenesis 8.446256e-3
GO:0045657 positive regulation of monocyte differentiation 8.479499e-3
GO:0002384 hepatic immune response 8.479499e-3
GO:0051293 establishment of spindle localization 8.548738e-3
GO:0060737 prostate gland morphogenetic growth 8.640104e-3
GO:0032350 regulation of hormone metabolic process 8.742593e-3
GO:0007006 mitochondrial membrane organization 8.893296e-3
GO:0042508 tyrosine phosphorylation of Stat1 protein 8.971188e-3
GO:0021513 spinal cord dorsal/ventral patterning 8.983310e-3
GO:0021955 central nervous system neuron axonogenesis 8.994736e-3
GO:0006633 fatty acid biosynthetic process 8.997794e-3
GO:0051896 regulation of protein kinase B signaling cascade 9.025341e-3
GO:0046111 xanthine biosynthetic process 9.048200e-3
GO:0060407 negative regulation of penile erection 9.048200e-3
GO:0060169 negative regulation of adenosine receptor signaling pathway 9.048200e-3
GO:0010825 positive regulation of centrosome duplication 9.048200e-3
GO:0002314 germinal center B cell differentiation 9.048200e-3
GO:0006157 deoxyadenosine catabolic process 9.048200e-3
GO:0046061 dATP catabolic process 9.048200e-3
GO:0007010 cytoskeleton organization 9.084844e-3
GO:0043543 protein acylation 9.280925e-3
GO:0016264 gap junction assembly 9.296363e-3
GO:0006297 nucleotide-excision repair, DNA gap filling 9.380778e-3
GO:0010587 miRNA catabolic process 9.430010e-3
GO:0002052 positive regulation of neuroblast proliferation 9.485793e-3
GO:0060648 mammary gland bud morphogenesis 9.537310e-3
GO:0002158 osteoclast proliferation 9.619344e-3
GO:0046058 cAMP metabolic process 9.648875e-3
GO:0009950 dorsal/ventral axis specification 9.916737e-3
GO:0044257 cellular protein catabolic process 1.001387e-2
GO:0003208 cardiac ventricle morphogenesis 1.002452e-2
GO:0003401 axis elongation 1.008424e-2
GO:0006281 DNA repair 1.014033e-2
GO:0046129 purine ribonucleoside biosynthetic process 1.015395e-2
GO:0043089 positive regulation of Cdc42 GTPase activity 1.018603e-2
GO:0007628 adult walking behavior 1.021579e-2
GO:0009156 ribonucleoside monophosphate biosynthetic process 1.026673e-2
GO:0006366 transcription from RNA polymerase II promoter 1.034561e-2
GO:0006259 DNA metabolic process 1.035967e-2


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0044237 cellular metabolic process 1.055696e-13
GO:0001830 trophectodermal cell fate commitment 7.170232e-11
GO:0021903 rostrocaudal neural tube patterning 9.713837e-11
GO:0016191 synaptic vesicle uncoating 2.147047e-10
GO:0001708 cell fate specification 2.972389e-10
GO:0010960 magnesium ion homeostasis 6.151222e-10
GO:0003207 cardiac chamber formation 6.736826e-10
GO:0003211 cardiac ventricle formation 1.180541e-9
GO:0044260 cellular macromolecule metabolic process 1.881247e-9
GO:0014033 neural crest cell differentiation 2.171736e-9
GO:0048562 embryonic organ morphogenesis 2.505350e-9
GO:0045165 cell fate commitment 3.211179e-9
GO:0060485 mesenchyme development 6.795951e-9
GO:0015074 DNA integration 7.310266e-9
GO:0021522 spinal cord motor neuron differentiation 8.867652e-9
GO:0060173 limb development 9.716247e-9
GO:0009950 dorsal/ventral axis specification 1.060436e-8
GO:0006139 nucleobase-containing compound metabolic process 1.116972e-8
GO:0048483 autonomic nervous system development 1.177745e-8
GO:0048705 skeletal system morphogenesis 1.411125e-8
GO:0072539 T-helper 17 cell differentiation 1.471974e-8
GO:0021532 neural tube patterning 1.679251e-8
GO:0001501 skeletal system development 1.827234e-8
GO:0048485 sympathetic nervous system development 1.829291e-8
GO:0060045 positive regulation of cardiac muscle cell proliferation 2.439795e-8
GO:0001649 osteoblast differentiation 2.475220e-8
GO:0048762 mesenchymal cell differentiation 3.858402e-8
GO:0006685 sphingomyelin catabolic process 4.075981e-8
GO:0014898 cardiac muscle hypertrophy in response to stress 4.994055e-8
GO:0090304 nucleic acid metabolic process 5.356142e-8
GO:0034641 cellular nitrogen compound metabolic process 6.182252e-8
GO:0046452 dihydrofolate metabolic process 6.859679e-8
GO:0090263 positive regulation of canonical Wnt receptor signaling pathway 1.118622e-7
GO:0030182 neuron differentiation 1.169722e-7
GO:0048242 epinephrine secretion 1.280060e-7
GO:0060025 regulation of synaptic activity 1.332409e-7
GO:2000987 positive regulation of behavioral fear response 1.332409e-7
GO:0003185 sinoatrial valve morphogenesis 1.332409e-7
GO:0003138 primary heart field specification 1.332409e-7
GO:0035984 cellular response to trichostatin A 1.332409e-7
GO:0071864 positive regulation of cell proliferation in bone marrow 1.431936e-7
GO:0035136 forelimb morphogenesis 1.492055e-7
GO:0071560 cellular response to transforming growth factor beta stimulus 1.538773e-7
GO:0000279 M phase 1.752431e-7
GO:0044238 primary metabolic process 1.913322e-7
GO:0035108 limb morphogenesis 2.439671e-7
GO:0003170 heart valve development 2.485435e-7
GO:0003007 heart morphogenesis 2.838891e-7
GO:0045652 regulation of megakaryocyte differentiation 3.060745e-7
GO:2000111 positive regulation of macrophage apoptosis 3.421528e-7
GO:0003179 heart valve morphogenesis 3.488996e-7
GO:0021520 spinal cord motor neuron cell fate specification 3.640007e-7
GO:0006807 nitrogen compound metabolic process 4.288797e-7
GO:0021918 regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment 4.627703e-7
GO:0021905 forebrain-midbrain boundary formation 4.627703e-7
GO:0003322 pancreatic A cell development 4.627703e-7
GO:0021902 commitment of neuronal cell to specific neuron type in forebrain 4.627703e-7
GO:0046475 glycerophospholipid catabolic process 4.919951e-7
GO:0002052 positive regulation of neuroblast proliferation 4.967889e-7
GO:0045885 positive regulation of survival gene product expression 5.617181e-7
GO:0060563 neuroepithelial cell differentiation 7.720725e-7
GO:0071559 response to transforming growth factor beta stimulus 8.084510e-7
GO:0006414 translational elongation 8.174065e-7
GO:0009953 dorsal/ventral pattern formation 8.279999e-7
GO:0014009 glial cell proliferation 9.048942e-7
GO:0003300 cardiac muscle hypertrophy 9.133427e-7
GO:0048703 embryonic viscerocranium morphogenesis 9.181873e-7
GO:0003151 outflow tract morphogenesis 9.672749e-7
GO:0048598 embryonic morphogenesis 1.005903e-6
GO:0008152 metabolic process 1.025184e-6
GO:0021515 cell differentiation in spinal cord 1.137975e-6
GO:0071380 cellular response to prostaglandin E stimulus 1.308911e-6
GO:0072358 cardiovascular system development 1.320915e-6
GO:0060349 bone morphogenesis 1.388860e-6
GO:0035426 extracellular matrix-cell signaling 1.643701e-6
GO:0034645 cellular macromolecule biosynthetic process 1.677141e-6
GO:0055075 potassium ion homeostasis 1.697690e-6
GO:2000053 regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification 1.704182e-6
GO:2000822 regulation of behavioral fear response 1.781370e-6
GO:0033092 positive regulation of immature T cell proliferation in thymus 1.832685e-6
GO:0006683 galactosylceramide catabolic process 1.858824e-6
GO:0072523 purine-containing compound catabolic process 1.865302e-6
GO:0006195 purine nucleotide catabolic process 1.924311e-6
GO:0009058 biosynthetic process 1.931767e-6
GO:0001947 heart looping 2.051879e-6
GO:0003357 noradrenergic neuron differentiation 2.179929e-6
GO:0060070 canonical Wnt receptor signaling pathway 2.229938e-6
GO:0071374 cellular response to parathyroid hormone stimulus 2.399712e-6
GO:0060828 regulation of canonical Wnt receptor signaling pathway 2.409022e-6
GO:0006357 regulation of transcription from RNA polymerase II promoter 2.632035e-6
GO:0010467 gene expression 2.747151e-6
GO:0090073 positive regulation of protein homodimerization activity 2.775375e-6
GO:0021796 cerebral cortex regionalization 2.874825e-6
GO:0009887 organ morphogenesis 2.875502e-6
GO:0051443 positive regulation of ubiquitin-protein ligase activity 3.150385e-6
GO:0034498 early endosome to Golgi transport 3.177130e-6
GO:2000109 regulation of macrophage apoptosis 3.202527e-6
GO:0003139 secondary heart field specification 3.418274e-6
GO:2001013 epithelial cell proliferation involve in renal tubule morphogenesis 3.687206e-6
GO:0072160 nephron tubule epithelial cell differentiation 3.687206e-6
GO:0060174 limb bud formation 3.773350e-6
GO:0060914 heart formation 3.862116e-6
GO:0060536 cartilage morphogenesis 4.186432e-6
GO:0043496 regulation of protein homodimerization activity 4.201324e-6
GO:0009059 macromolecule biosynthetic process 4.235361e-6
GO:0002244 hemopoietic progenitor cell differentiation 4.385017e-6
GO:0030224 monocyte differentiation 4.434910e-6
GO:0051261 protein depolymerization 4.556770e-6
GO:0033091 positive regulation of immature T cell proliferation 4.556770e-6
GO:2000761 positive regulation of N-terminal peptidyl-lysine acetylation 4.701822e-6
GO:0035910 ascending aorta morphogenesis 4.701822e-6
GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification 4.826305e-6
GO:0045778 positive regulation of ossification 5.053424e-6
GO:0007067 mitosis 5.228369e-6
GO:0070848 response to growth factor stimulus 5.277498e-6
GO:0071363 cellular response to growth factor stimulus 5.290295e-6
GO:0045717 negative regulation of fatty acid biosynthetic process 6.186982e-6
GO:0033692 cellular polysaccharide biosynthetic process 6.518639e-6
GO:0002320 lymphoid progenitor cell differentiation 6.729130e-6
GO:0021930 cerebellar granule cell precursor proliferation 6.869385e-6
GO:0044249 cellular biosynthetic process 7.029712e-6
GO:0009166 nucleotide catabolic process 7.117621e-6
GO:0010628 positive regulation of gene expression 7.190251e-6
GO:0070286 axonemal dynein complex assembly 7.362272e-6
GO:0048854 brain morphogenesis 7.954782e-6
GO:0042769 DNA damage response, detection of DNA damage 8.139163e-6
GO:0005978 glycogen biosynthetic process 9.012499e-6
GO:0000087 M phase of mitotic cell cycle 9.087158e-6
GO:0071498 cellular response to fluid shear stress 9.332351e-6
GO:0048285 organelle fission 9.433444e-6
GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway 9.493965e-6
GO:0007000 nucleolus organization 9.713472e-6
GO:0060043 regulation of cardiac muscle cell proliferation 9.750217e-6
GO:0000902 cell morphogenesis 1.004186e-5
GO:0055078 sodium ion homeostasis 1.025829e-5
GO:2000179 positive regulation of neural precursor cell proliferation 1.173472e-5
GO:0010557 positive regulation of macromolecule biosynthetic process 1.178332e-5
GO:0071107 response to parathyroid hormone stimulus 1.196075e-5
GO:0003310 pancreatic A cell differentiation 1.196075e-5
GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification 1.226578e-5
GO:0021915 neural tube development 1.287604e-5
GO:0016070 RNA metabolic process 1.347953e-5
GO:0007521 muscle cell fate determination 1.350493e-5
GO:0002328 pro-B cell differentiation 1.350493e-5
GO:0048858 cell projection morphogenesis 1.350588e-5
GO:0030177 positive regulation of Wnt receptor signaling pathway 1.366824e-5
GO:0055024 regulation of cardiac muscle tissue development 1.386871e-5
GO:0045893 positive regulation of transcription, DNA-dependent 1.399503e-5
GO:0021978 telencephalon regionalization 1.436654e-5
GO:2000271 positive regulation of fibroblast apoptosis 1.471305e-5
GO:2000270 negative regulation of fibroblast apoptosis 1.471305e-5
GO:0044345 stromal-epithelial cell signaling involved in prostate gland development 1.471305e-5
GO:2000080 negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation 1.471305e-5
GO:0097070 ductus arteriosus closure 1.491216e-5
GO:0046700 heterocycle catabolic process 1.536967e-5
GO:0021568 rhombomere 2 development 1.634165e-5
GO:0044264 cellular polysaccharide metabolic process 1.664566e-5
GO:0050850 positive regulation of calcium-mediated signaling 1.723512e-5
GO:0045884 regulation of survival gene product expression 1.723512e-5
GO:0009987 cellular process 1.767219e-5
GO:0045666 positive regulation of neuron differentiation 1.854451e-5
GO:0001667 ameboidal cell migration 1.854451e-5
GO:0002149 hypochlorous acid biosynthetic process 1.871132e-5
GO:0046856 phosphatidylinositol dephosphorylation 1.906092e-5
GO:0003091 renal water homeostasis 1.906092e-5
GO:0048596 embryonic camera-type eye morphogenesis 1.951172e-5
GO:0001709 cell fate determination 1.958671e-5
GO:0010604 positive regulation of macromolecule metabolic process 2.066054e-5
GO:0014029 neural crest formation 2.127610e-5
GO:0035909 aorta morphogenesis 2.141561e-5
GO:2000079 regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation 2.202439e-5
GO:0042093 T-helper cell differentiation 2.331183e-5
GO:0048048 embryonic eye morphogenesis 2.432707e-5
GO:0050432 catecholamine secretion 2.504719e-5
GO:0043170 macromolecule metabolic process 2.522820e-5
GO:0021510 spinal cord development 2.573404e-5
GO:0005980 glycogen catabolic process 2.586501e-5
GO:0000122 negative regulation of transcription from RNA polymerase II promoter 2.758695e-5
GO:0014031 mesenchymal cell development 2.827846e-5
GO:0051254 positive regulation of RNA metabolic process 2.888433e-5
GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation 2.983968e-5
GO:0051216 cartilage development 2.988133e-5
GO:0032990 cell part morphogenesis 3.011409e-5
GO:0021517 ventral spinal cord development 3.012392e-5
GO:0006298 mismatch repair 3.017811e-5
GO:0060350 endochondral bone morphogenesis 3.126381e-5
GO:0048241 epinephrine transport 3.260488e-5
GO:0055021 regulation of cardiac muscle tissue growth 3.307110e-5
GO:0031076 embryonic camera-type eye development 3.307110e-5
GO:0051351 positive regulation of ligase activity 3.339664e-5
GO:0010900 negative regulation of phosphatidylcholine catabolic process 3.365065e-5
GO:0003206 cardiac chamber morphogenesis 3.417657e-5
GO:0030318 melanocyte differentiation 3.473183e-5
GO:0045065 cytotoxic T cell differentiation 3.512672e-5
GO:0010694 positive regulation of alkaline phosphatase activity 3.745383e-5
GO:0072102 glomerulus morphogenesis 3.745577e-5
GO:0007507 heart development 3.867280e-5
GO:0031018 endocrine pancreas development 3.881391e-5
GO:0001568 blood vessel development 3.917587e-5
GO:0016082 synaptic vesicle priming 4.046659e-5
GO:0003208 cardiac ventricle morphogenesis 4.108647e-5
GO:0035810 positive regulation of urine volume 4.119393e-5
GO:0009143 nucleoside triphosphate catabolic process 4.134361e-5
GO:0016055 Wnt receptor signaling pathway 4.261699e-5
GO:0009146 purine nucleoside triphosphate catabolic process 4.480979e-5
GO:0042472 inner ear morphogenesis 4.566492e-5
GO:0050931 pigment cell differentiation 4.847489e-5
GO:2000050 regulation of non-canonical Wnt receptor signaling pathway 4.991520e-5
GO:0009207 purine ribonucleoside triphosphate catabolic process 5.019333e-5
GO:0006681 galactosylceramide metabolic process 5.087703e-5
GO:0021953 central nervous system neuron differentiation 5.149547e-5
GO:0034655 nucleobase-containing compound catabolic process 5.197593e-5
GO:0034435 cholesterol esterification 5.381792e-5
GO:0031325 positive regulation of cellular metabolic process 5.447725e-5
GO:0003205 cardiac chamber development 5.480519e-5
GO:0010092 specification of organ identity 5.553309e-5
GO:0007267 cell-cell signaling 5.563794e-5
GO:0045401 positive regulation of interleukin-3 biosynthetic process 5.571928e-5
GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process 5.571928e-5
GO:0045922 negative regulation of fatty acid metabolic process 5.586664e-5
GO:0060297 regulation of sarcomere organization 5.673293e-5
GO:0000710 meiotic mismatch repair 5.763682e-5
GO:0019047 provirus integration 5.947200e-5
GO:0030258 lipid modification 6.084349e-5
GO:0031328 positive regulation of cellular biosynthetic process 6.125275e-5
GO:0043624 cellular protein complex disassembly 6.272991e-5
GO:0003231 cardiac ventricle development 6.337717e-5
GO:0048066 developmental pigmentation 6.390099e-5
GO:0005977 glycogen metabolic process 6.601161e-5
GO:0046826 negative regulation of protein export from nucleus 6.696958e-5
GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process 7.110560e-5
GO:0051005 negative regulation of lipoprotein lipase activity 7.450353e-5
GO:0014896 muscle hypertrophy 7.501298e-5
GO:0009893 positive regulation of metabolic process 7.502358e-5
GO:0032463 negative regulation of protein homooligomerization 7.522198e-5
GO:0032808 lacrimal gland development 7.672728e-5
GO:0022403 cell cycle phase 7.701865e-5
GO:0035137 hindlimb morphogenesis 7.702565e-5
GO:0009154 purine ribonucleotide catabolic process 7.961059e-5
GO:0003279 cardiac septum development 8.057819e-5
GO:0042471 ear morphogenesis 8.925131e-5
GO:0045667 regulation of osteoblast differentiation 9.053956e-5
GO:0060562 epithelial tube morphogenesis 9.124686e-5
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 9.249193e-5
GO:0009268 response to pH 9.409216e-5
GO:0010922 positive regulation of phosphatase activity 9.648504e-5
GO:0032462 regulation of protein homooligomerization 9.802155e-5
GO:0019229 regulation of vasoconstriction 9.888068e-5
GO:0071333 cellular response to glucose stimulus 9.934872e-5
GO:0007611 learning or memory 1.007869e-4
GO:0060012 synaptic transmission, glycinergic 1.037909e-4
GO:0042693 muscle cell fate commitment 1.062895e-4
GO:0050848 regulation of calcium-mediated signaling 1.074353e-4
GO:0051438 regulation of ubiquitin-protein ligase activity 1.102705e-4
GO:0071481 cellular response to X-ray 1.107075e-4
GO:0043241 protein complex disassembly 1.116866e-4
GO:0003140 determination of left/right asymmetry in lateral mesoderm 1.132445e-4
GO:0001692 histamine metabolic process 1.132445e-4
GO:0015739 sialic acid transport 1.154458e-4
GO:0044270 cellular nitrogen compound catabolic process 1.179426e-4
GO:0009261 ribonucleotide catabolic process 1.206346e-4
GO:0017145 stem cell division 1.242604e-4
GO:0050890 cognition 1.250670e-4
GO:0048103 somatic stem cell division 1.287502e-4
GO:0001503 ossification 1.315353e-4
GO:0032092 positive regulation of protein binding 1.327966e-4
GO:0022402 cell cycle process 1.341392e-4
GO:0048699 generation of neurons 1.354157e-4
GO:0003289 atrial septum primum morphogenesis 1.370100e-4
GO:0001944 vasculature development 1.371209e-4
GO:0002293 alpha-beta T cell differentiation involved in immune response 1.381214e-4
GO:0043588 skin development 1.387448e-4
GO:0045669 positive regulation of osteoblast differentiation 1.396224e-4
GO:0006355 regulation of transcription, DNA-dependent 1.411966e-4
GO:0009891 positive regulation of biosynthetic process 1.438158e-4
GO:0010834 telomere maintenance via telomere shortening 1.484235e-4
GO:0030149 sphingolipid catabolic process 1.501324e-4
GO:0061301 cerebellum vasculature morphogenesis 1.509394e-4
GO:0021938 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation 1.569158e-4
GO:0021872 forebrain generation of neurons 1.576067e-4
GO:0010556 regulation of macromolecule biosynthetic process 1.611598e-4
GO:0006163 purine nucleotide metabolic process 1.655624e-4
GO:0060632 regulation of microtubule-based movement 1.692179e-4
GO:0002287 alpha-beta T cell activation involved in immune response 1.768971e-4
GO:0009259 ribonucleotide metabolic process 1.774771e-4
GO:0001662 behavioral fear response 1.810327e-4
GO:0035904 aorta development 1.818067e-4
GO:0021873 forebrain neuroblast division 1.871203e-4
GO:0043951 negative regulation of cAMP-mediated signaling 1.917162e-4
GO:0042461 photoreceptor cell development 1.917837e-4
GO:0034447 very-low-density lipoprotein particle clearance 1.918695e-4
GO:0006112 energy reserve metabolic process 1.938303e-4
GO:0015804 neutral amino acid transport 1.949247e-4
GO:0060411 cardiac septum morphogenesis 1.990541e-4
GO:0055012 ventricular cardiac muscle cell differentiation 2.002584e-4
GO:0002209 behavioral defense response 2.002584e-4
GO:0033979 box H/ACA snoRNA metabolic process 2.016988e-4
GO:0006682 galactosylceramide biosynthetic process 2.016988e-4
GO:0009653 anatomical structure morphogenesis 2.079755e-4
GO:0002098 tRNA wobble uridine modification 2.084766e-4
GO:2000344 positive regulation of acrosome reaction 2.184552e-4
GO:2000054 negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification 2.184552e-4
GO:0035567 non-canonical Wnt receptor signaling pathway 2.197306e-4
GO:0042596 fear response 2.204374e-4
GO:0043968 histone H2A acetylation 2.232786e-4
GO:0048704 embryonic skeletal system morphogenesis 2.393279e-4
GO:0021778 oligodendrocyte cell fate specification 2.401766e-4
GO:0010921 regulation of phosphatase activity 2.439743e-4
GO:0060348 bone development 2.446385e-4
GO:0033084 regulation of immature T cell proliferation in thymus 2.448635e-4
GO:0002634 regulation of germinal center formation 2.500735e-4
GO:0044340 canonical Wnt receptor signaling pathway involved in regulation of cell proliferation 2.523145e-4
GO:0060420 regulation of heart growth 2.545051e-4
GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production 2.559265e-4
GO:0048643 positive regulation of skeletal muscle tissue development 2.564510e-4
GO:0015844 monoamine transport 2.569032e-4
GO:0051173 positive regulation of nitrogen compound metabolic process 2.590303e-4
GO:0001755 neural crest cell migration 2.590727e-4
GO:0003002 regionalization 2.592283e-4
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 2.599629e-4
GO:0060271 cilium morphogenesis 2.710961e-4
GO:0051225 spindle assembly 2.744338e-4
GO:0035914 skeletal muscle cell differentiation 2.843617e-4
GO:0045595 regulation of cell differentiation 2.898944e-4
GO:0021513 spinal cord dorsal/ventral patterning 2.904524e-4
GO:0001678 cellular glucose homeostasis 2.944003e-4
GO:0046839 phospholipid dephosphorylation 2.984896e-4
GO:0050973 detection of mechanical stimulus involved in equilibrioception 2.998412e-4
GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway 3.032707e-4
GO:0072404 signal transduction involved in G1/S transition checkpoint 3.032907e-4
GO:0007049 cell cycle 3.052605e-4
GO:0006184 GTP catabolic process 3.064322e-4
GO:0048665 neuron fate specification 3.082088e-4
GO:0009205 purine ribonucleoside triphosphate metabolic process 3.244839e-4
GO:0060668 regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling 3.263036e-4
GO:0033005 positive regulation of mast cell activation 3.279072e-4
GO:0048852 diencephalon morphogenesis 3.290679e-4
GO:0033239 negative regulation of cellular amine metabolic process 3.412777e-4
GO:0048666 neuron development 3.425185e-4
GO:0009199 ribonucleoside triphosphate metabolic process 3.460116e-4
GO:0071777 positive regulation of cell cycle cytokinesis 3.469606e-4
GO:0051340 regulation of ligase activity 3.470130e-4
GO:0048568 embryonic organ development 3.492410e-4
GO:0030220 platelet formation 3.548196e-4
GO:0048645 organ formation 3.585352e-4
GO:0090307 spindle assembly involved in mitosis 3.621626e-4
GO:0035809 regulation of urine volume 3.642444e-4
GO:0015837 amine transport 3.716227e-4
GO:0030890 positive regulation of B cell proliferation 3.744038e-4
GO:0071219 cellular response to molecule of bacterial origin 3.776320e-4
GO:0009150 purine ribonucleotide metabolic process 3.798415e-4
GO:0071222 cellular response to lipopolysaccharide 3.802354e-4
GO:2000117 negative regulation of cysteine-type endopeptidase activity 3.833970e-4
GO:0007228 positive regulation of hh target transcription factor activity 3.833970e-4
GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process 3.843897e-4
GO:0001820 serotonin secretion 3.873258e-4
GO:0033083 regulation of immature T cell proliferation 3.880117e-4
GO:0021546 rhombomere development 3.880117e-4
GO:0071322 cellular response to carbohydrate stimulus 3.958111e-4
GO:0046888 negative regulation of hormone secretion 4.078385e-4
GO:0060413 atrial septum morphogenesis 4.105530e-4
GO:0009141 nucleoside triphosphate metabolic process 4.171145e-4
GO:0006366 transcription from RNA polymerase II promoter 4.209260e-4
GO:0030501 positive regulation of bone mineralization 4.235493e-4
GO:0060484 lung-associated mesenchyme development 4.299439e-4
GO:0007131 reciprocal meiotic recombination 4.299439e-4
GO:0003283 atrial septum development 4.304076e-4
GO:0061351 neural precursor cell proliferation 4.304301e-4
GO:0072395 signal transduction involved in cell cycle checkpoint 4.398457e-4
GO:0072080 nephron tubule development 4.402933e-4
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 4.439850e-4
GO:0006351 transcription, DNA-dependent 4.704467e-4
GO:0031427 response to methotrexate 4.727637e-4
GO:0044130 negative regulation of growth of symbiont in host 4.740669e-4
GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway 4.761169e-4
GO:0072285 mesenchymal to epithelial transition involved in metanephric renal vesicle formation 4.761169e-4
GO:0060248 detection of cell density by contact stimulus involved in contact inhibition 4.761169e-4
GO:0007371 ventral midline determination 4.761169e-4
GO:0001841 neural tube formation 4.769722e-4
GO:0006400 tRNA modification 4.884605e-4
GO:0032185 septin cytoskeleton organization 4.977411e-4
GO:0051252 regulation of RNA metabolic process 4.982774e-4
GO:0071236 cellular response to antibiotic 5.003040e-4
GO:0070169 positive regulation of biomineral tissue development 5.050830e-4
GO:0050891 multicellular organismal water homeostasis 5.144927e-4
GO:0060687 regulation of branching involved in prostate gland morphogenesis 5.158636e-4
GO:0031396 regulation of protein ubiquitination 5.193570e-4
GO:0032774 RNA biosynthetic process 5.264788e-4
GO:0035050 embryonic heart tube development 5.429051e-4
GO:0045732 positive regulation of protein catabolic process 5.481526e-4
GO:0042462 eye photoreceptor cell development 5.507401e-4
GO:0045599 negative regulation of fat cell differentiation 5.536062e-4
GO:0043570 maintenance of DNA repeat elements 5.570858e-4
GO:0042178 xenobiotic catabolic process 5.570858e-4
GO:0007172 signal complex assembly 5.775441e-4
GO:0048853 forebrain morphogenesis 5.802222e-4
GO:0009144 purine nucleoside triphosphate metabolic process 5.858977e-4
GO:0033238 regulation of cellular amine metabolic process 5.881274e-4
GO:0035607 fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development 5.954123e-4
GO:0051096 positive regulation of helicase activity 5.954123e-4
GO:0050803 regulation of synapse structure and activity 5.974304e-4
GO:0008544 epidermis development 6.026896e-4
GO:0003281 ventricular septum development 6.046764e-4
GO:0035115 embryonic forelimb morphogenesis 6.048852e-4
GO:0045844 positive regulation of striated muscle tissue development 6.057758e-4
GO:2000112 regulation of cellular macromolecule biosynthetic process 6.136216e-4
GO:0060696 regulation of phospholipid catabolic process 6.256279e-4
GO:0050771 negative regulation of axonogenesis 6.305359e-4
GO:0009117 nucleotide metabolic process 6.493111e-4
GO:0048663 neuron fate commitment 6.514717e-4
GO:0007566 embryo implantation 6.604269e-4
GO:0006545 glycine biosynthetic process 6.678043e-4
GO:0001550 ovarian cumulus expansion 6.678043e-4
GO:0030858 positive regulation of epithelial cell differentiation 6.780451e-4
GO:0007612 learning 6.813180e-4
GO:0045597 positive regulation of cell differentiation 6.922637e-4
GO:0060296 regulation of cilium beat frequency involved in ciliary motility 6.952667e-4
GO:0010963 regulation of L-arginine import 6.994825e-4
GO:0046039 GTP metabolic process 6.996636e-4
GO:0030910 olfactory placode formation 7.009073e-4
GO:0014032 neural crest cell development 7.309887e-4
GO:0032989 cellular component morphogenesis 7.344929e-4
GO:0043586 tongue development 7.366639e-4
GO:0021511 spinal cord patterning 7.477902e-4
GO:0071391 cellular response to estrogen stimulus 7.636988e-4
GO:0035239 tube morphogenesis 7.868029e-4
GO:2000678 negative regulation of transcription regulatory region DNA binding 8.035553e-4
GO:0072044 collecting duct development 8.203610e-4
GO:0035329 hippo signaling cascade 8.286894e-4
GO:0061326 renal tubule development 8.328679e-4
GO:0045944 positive regulation of transcription from RNA polymerase II promoter 8.366636e-4
GO:0035987 endodermal cell differentiation 8.367266e-4
GO:0006611 protein export from nucleus 8.406256e-4
GO:0008284 positive regulation of cell proliferation 8.426382e-4
GO:0007257 activation of JUN kinase activity 8.626499e-4
GO:0043589 skin morphogenesis 8.664376e-4
GO:0060412 ventricular septum morphogenesis 8.676715e-4
GO:0001711 endodermal cell fate commitment 8.878650e-4
GO:0072009 nephron epithelium development 9.087982e-4
GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism 9.091225e-4
GO:0021879 forebrain neuron differentiation 9.185205e-4
GO:0048227 plasma membrane to endosome transport 9.259725e-4
GO:0071423 malate transmembrane transport 9.259725e-4
GO:0015709 thiosulfate transport 9.259725e-4
GO:0032474 otolith morphogenesis 9.259725e-4
GO:0010430 fatty acid omega-oxidation 9.259725e-4
GO:2000727 positive regulation of cardiac muscle cell differentiation 9.278273e-4
GO:0002062 chondrocyte differentiation 9.331823e-4
GO:0009103 lipopolysaccharide biosynthetic process 9.345088e-4
GO:0000272 polysaccharide catabolic process 9.431137e-4
GO:0030030 cell projection organization 9.577671e-4
GO:0033144 negative regulation of steroid hormone receptor signaling pathway 9.887658e-4
GO:0021506 anterior neuropore closure 1.005152e-3
GO:0006796 phosphate-containing compound metabolic process 1.013390e-3
GO:0007254 JNK cascade 1.019610e-3
GO:0021984 adenohypophysis development 1.021873e-3
GO:0072521 purine-containing compound metabolic process 1.024058e-3
GO:0048706 embryonic skeletal system development 1.035893e-3
GO:0046620 regulation of organ growth 1.065648e-3
GO:0060071 Wnt receptor signaling pathway, planar cell polarity pathway 1.074789e-3
GO:0043366 beta selection 1.076194e-3
GO:0051095 regulation of helicase activity 1.076194e-3
GO:0002286 T cell activation involved in immune response 1.098457e-3
GO:0048646 anatomical structure formation involved in morphogenesis 1.114268e-3
GO:0030111 regulation of Wnt receptor signaling pathway 1.115559e-3
GO:0007405 neuroblast proliferation 1.148725e-3
GO:0010468 regulation of gene expression 1.149398e-3
GO:0009889 regulation of biosynthetic process 1.155171e-3
GO:0022008 neurogenesis 1.181805e-3
GO:0016477 cell migration 1.228581e-3
GO:0050821 protein stabilization 1.233955e-3
GO:0048839 inner ear development 1.239970e-3
GO:0046530 photoreceptor cell differentiation 1.254887e-3
GO:0021514 ventral spinal cord interneuron differentiation 1.267413e-3
GO:0035850 epithelial cell differentiation involved in kidney development 1.267413e-3
GO:0033689 negative regulation of osteoblast proliferation 1.270877e-3
GO:0002009 morphogenesis of an epithelium 1.272532e-3
GO:0051788 response to misfolded protein 1.282935e-3
GO:0031398 positive regulation of protein ubiquitination 1.302241e-3
GO:0031326 regulation of cellular biosynthetic process 1.326419e-3
GO:0050871 positive regulation of B cell activation 1.358579e-3
GO:0048812 neuron projection morphogenesis 1.359839e-3
GO:0030901 midbrain development 1.360167e-3
GO:0061316 canonical Wnt receptor signaling pathway involved in heart development 1.396637e-3
GO:0001714 endodermal cell fate specification 1.402246e-3
GO:0030917 midbrain-hindbrain boundary development 1.410086e-3
GO:0072006 nephron development 1.419803e-3
GO:0030032 lamellipodium assembly 1.420410e-3
GO:0051930 regulation of sensory perception of pain 1.429784e-3
GO:0061136 regulation of proteasomal protein catabolic process 1.452436e-3
GO:0032204 regulation of telomere maintenance 1.459996e-3
GO:0021779 oligodendrocyte cell fate commitment 1.517538e-3
GO:0001101 response to acid 1.522366e-3
GO:0021523 somatic motor neuron differentiation 1.530415e-3
GO:0050864 regulation of B cell activation 1.563248e-3
GO:0034651 cortisol biosynthetic process 1.575848e-3
GO:0035865 cellular response to potassium ion 1.575848e-3
GO:0015887 pantothenate transmembrane transport 1.575848e-3
GO:0015878 biotin transport 1.575848e-3
GO:0001309 age-dependent telomere shortening 1.575848e-3