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Novel motif:116

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name:motif116_CCAARA

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0048739 cardiac muscle fiber development 4.726030e-32
GO:0030241 skeletal muscle myosin thick filament assembly 2.342931e-25
GO:0030049 muscle filament sliding 1.858757e-23
GO:0070252 actin-mediated cell contraction 1.410107e-22
GO:0030048 actin filament-based movement 2.502953e-22
GO:0006941 striated muscle contraction 6.395242e-22
GO:0048738 cardiac muscle tissue development 2.157012e-20
GO:0014866 skeletal myofibril assembly 5.694535e-20
GO:0009611 response to wounding 6.317441e-19
GO:0006936 muscle contraction 1.551633e-18
GO:0006928 cellular component movement 1.732680e-18
GO:0051179 localization 5.863073e-17
GO:0010951 negative regulation of endopeptidase activity 6.008940e-17
GO:0006954 inflammatory response 8.356319e-17
GO:0030239 myofibril assembly 1.026234e-16
GO:0055013 cardiac muscle cell development 2.571776e-16
GO:0051234 establishment of localization 2.687832e-16
GO:0048769 sarcomerogenesis 3.301022e-16
GO:0030261 chromosome condensation 7.700767e-16
GO:0003012 muscle system process 8.163395e-16
GO:0006810 transport 1.983512e-15
GO:0010927 cellular component assembly involved in morphogenesis 2.052364e-15
GO:0048644 muscle organ morphogenesis 3.956752e-15
GO:0046890 regulation of lipid biosynthetic process 4.445083e-15
GO:0060415 muscle tissue morphogenesis 7.225723e-15
GO:0031032 actomyosin structure organization 8.861612e-15
GO:0006950 response to stress 1.474726e-14
GO:0045214 sarcomere organization 2.796368e-14
GO:0030029 actin filament-based process 3.008863e-14
GO:0055008 cardiac muscle tissue morphogenesis 5.385385e-14
GO:0006952 defense response 1.220494e-13
GO:0002576 platelet degranulation 1.895881e-13
GO:0051146 striated muscle cell differentiation 2.548678e-13
GO:0042221 response to chemical stimulus 2.558040e-13
GO:0048251 elastic fiber assembly 4.405357e-13
GO:0019216 regulation of lipid metabolic process 6.313328e-13
GO:0051298 centrosome duplication 9.599251e-13
GO:0046903 secretion 1.218738e-12
GO:0006887 exocytosis 1.424586e-12
GO:0007076 mitotic chromosome condensation 2.647351e-12
GO:0050896 response to stimulus 4.693756e-12
GO:0034097 response to cytokine stimulus 5.223300e-12
GO:0048747 muscle fiber development 7.100378e-12
GO:0055001 muscle cell development 7.122606e-12
GO:0002376 immune system process 7.307108e-12
GO:0001775 cell activation 7.507511e-12
GO:0030240 skeletal muscle thin filament assembly 9.361800e-12
GO:0085029 extracellular matrix assembly 1.015052e-11
GO:0055007 cardiac muscle cell differentiation 1.030610e-11
GO:0055003 cardiac myofibril assembly 1.082232e-11
GO:0016192 vesicle-mediated transport 1.119293e-11
GO:0000070 mitotic sister chromatid segregation 1.432521e-11
GO:0010035 response to inorganic substance 1.991827e-11
GO:0009888 tissue development 2.433235e-11
GO:0032940 secretion by cell 2.530011e-11
GO:0010033 response to organic substance 3.045966e-11
GO:0000819 sister chromatid segregation 4.641159e-11
GO:0000279 M phase 5.115089e-11
GO:0050900 leukocyte migration 5.919756e-11
GO:0030010 establishment of cell polarity 8.449493e-11
GO:0051293 establishment of spindle localization 8.715682e-11
GO:0030036 actin cytoskeleton organization 9.194664e-11
GO:0051649 establishment of localization in cell 1.021926e-10
GO:0009725 response to hormone stimulus 1.149797e-10
GO:0046885 regulation of hormone biosynthetic process 1.593076e-10
GO:0055002 striated muscle cell development 1.629682e-10
GO:0060537 muscle tissue development 1.689037e-10
GO:0051641 cellular localization 1.708392e-10
GO:0006953 acute-phase response 2.190137e-10
GO:0003007 heart morphogenesis 2.601263e-10
GO:0046709 IDP catabolic process 2.660254e-10
GO:0046032 ADP catabolic process 2.660254e-10
GO:0000087 M phase of mitotic cell cycle 3.924790e-10
GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 4.857318e-10
GO:0006633 fatty acid biosynthetic process 4.901452e-10
GO:0007067 mitosis 4.916658e-10
GO:0003008 system process 5.824020e-10
GO:0032501 multicellular organismal process 6.792808e-10
GO:0006955 immune response 6.897935e-10
GO:0030100 regulation of endocytosis 7.075414e-10
GO:0006323 DNA packaging 7.096983e-10
GO:0030168 platelet activation 7.803559e-10
GO:0048513 organ development 8.694405e-10
GO:0010038 response to metal ion 9.898458e-10
GO:0048285 organelle fission 1.095725e-9
GO:0065008 regulation of biological quality 1.345116e-9
GO:0032637 interleukin-8 production 1.357720e-9
GO:0042060 wound healing 1.463627e-9
GO:0007098 centrosome cycle 1.494778e-9
GO:0044240 multicellular organismal lipid catabolic process 1.559561e-9
GO:0071103 DNA conformation change 2.028964e-9
GO:0014706 striated muscle tissue development 2.231728e-9
GO:0008645 hexose transport 2.974174e-9
GO:0009617 response to bacterium 3.170629e-9
GO:0015749 monosaccharide transport 4.108268e-9
GO:0034612 response to tumor necrosis factor 4.575644e-9
GO:0007507 heart development 4.672086e-9
GO:0010466 negative regulation of peptidase activity 4.905977e-9
GO:0040017 positive regulation of locomotion 5.079596e-9
GO:0090030 regulation of steroid hormone biosynthetic process 5.240095e-9
GO:0015758 glucose transport 5.389062e-9
GO:0030335 positive regulation of cell migration 6.070369e-9
GO:0046889 positive regulation of lipid biosynthetic process 6.146841e-9
GO:0051346 negative regulation of hydrolase activity 6.425751e-9
GO:0019218 regulation of steroid metabolic process 6.827642e-9
GO:0032879 regulation of localization 6.920274e-9
GO:0071345 cellular response to cytokine stimulus 7.242163e-9
GO:0050974 detection of mechanical stimulus involved in sensory perception 7.698746e-9
GO:0002028 regulation of sodium ion transport 9.027151e-9
GO:0071356 cellular response to tumor necrosis factor 9.619275e-9
GO:0043627 response to estrogen stimulus 1.042724e-8
GO:0007522 visceral muscle development 1.391728e-8
GO:0042446 hormone biosynthetic process 1.431568e-8
GO:2000147 positive regulation of cell motility 1.652492e-8
GO:0051272 positive regulation of cellular component movement 1.792030e-8
GO:0006869 lipid transport 1.877875e-8
GO:0016075 rRNA catabolic process 1.970640e-8
GO:0002526 acute inflammatory response 2.249791e-8
GO:0010876 lipid localization 2.288916e-8
GO:0031099 regeneration 2.318950e-8
GO:0009719 response to endogenous stimulus 2.749337e-8
GO:0006766 vitamin metabolic process 3.227701e-8
GO:0048520 positive regulation of behavior 3.499918e-8
GO:0010288 response to lead ion 3.547819e-8
GO:0022414 reproductive process 3.677415e-8
GO:0052548 regulation of endopeptidase activity 3.930243e-8
GO:0042692 muscle cell differentiation 4.100778e-8
GO:0006082 organic acid metabolic process 4.203794e-8
GO:0000003 reproduction 4.401287e-8
GO:0043434 response to peptide hormone stimulus 4.591373e-8
GO:0051704 multi-organism process 4.654264e-8
GO:0032103 positive regulation of response to external stimulus 5.055359e-8
GO:0010766 negative regulation of sodium ion transport 5.556665e-8
GO:0046886 positive regulation of hormone biosynthetic process 5.806693e-8
GO:0007010 cytoskeleton organization 5.998136e-8
GO:0051049 regulation of transport 6.314660e-8
GO:0007015 actin filament organization 6.379346e-8
GO:0050810 regulation of steroid biosynthetic process 7.097608e-8
GO:0072358 cardiovascular system development 7.549253e-8
GO:0050927 positive regulation of positive chemotaxis 7.695970e-8
GO:0046456 icosanoid biosynthetic process 9.637086e-8
GO:0007599 hemostasis 9.889395e-8
GO:0050921 positive regulation of chemotaxis 1.057401e-7
GO:0008228 opsonization 1.120319e-7
GO:0048646 anatomical structure formation involved in morphogenesis 1.135266e-7
GO:0060627 regulation of vesicle-mediated transport 1.312237e-7
GO:0032269 negative regulation of cellular protein metabolic process 1.414561e-7
GO:0050926 regulation of positive chemotaxis 1.469743e-7
GO:0007596 blood coagulation 1.515209e-7
GO:0051707 response to other organism 1.939545e-7
GO:0007163 establishment or maintenance of cell polarity 1.946114e-7
GO:0042180 cellular ketone metabolic process 2.083572e-7
GO:0072376 protein activation cascade 2.099802e-7
GO:0071702 organic substance transport 2.100056e-7
GO:0006636 unsaturated fatty acid biosynthetic process 2.115447e-7
GO:0052547 regulation of peptidase activity 2.231929e-7
GO:0048608 reproductive structure development 2.659001e-7
GO:0019752 carboxylic acid metabolic process 2.958367e-7
GO:0030593 neutrophil chemotaxis 3.024047e-7
GO:0044243 multicellular organismal catabolic process 3.065357e-7
GO:0050906 detection of stimulus involved in sensory perception 3.104813e-7
GO:0006959 humoral immune response 3.146305e-7
GO:0045807 positive regulation of endocytosis 3.157335e-7
GO:0045766 positive regulation of angiogenesis 3.327797e-7
GO:0040012 regulation of locomotion 3.472137e-7
GO:0009181 purine ribonucleoside diphosphate catabolic process 3.556118e-7
GO:0045940 positive regulation of steroid metabolic process 3.669100e-7
GO:0051248 negative regulation of protein metabolic process 3.696939e-7
GO:0006631 fatty acid metabolic process 4.070004e-7
GO:0001819 positive regulation of cytokine production 4.126679e-7
GO:0050878 regulation of body fluid levels 4.607159e-7
GO:0000132 establishment of mitotic spindle orientation 4.741209e-7
GO:0010574 regulation of vascular endothelial growth factor production 4.935731e-7
GO:0003230 cardiac atrium development 5.043739e-7
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 5.628621e-7
GO:0035051 cardiac cell differentiation 5.651016e-7
GO:0048870 cell motility 6.308218e-7
GO:0040001 establishment of mitotic spindle localization 6.802678e-7
GO:0034694 response to prostaglandin stimulus 7.219215e-7
GO:0061162 establishment of monopolar cell polarity 7.309939e-7
GO:0042493 response to drug 8.092025e-7
GO:0003026 regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback 8.587534e-7
GO:0001300 chronological cell aging 9.014253e-7
GO:0032101 regulation of response to external stimulus 9.075782e-7
GO:0050982 detection of mechanical stimulus 9.301662e-7
GO:0019724 B cell mediated immunity 9.304087e-7
GO:0032355 response to estradiol stimulus 9.330482e-7
GO:0003006 developmental process involved in reproduction 9.732737e-7
GO:0044236 multicellular organismal metabolic process 9.805532e-7
GO:0070555 response to interleukin-1 1.110101e-6
GO:0044085 cellular component biogenesis 1.188088e-6
GO:0042304 regulation of fatty acid biosynthetic process 1.193406e-6
GO:0051297 centrosome organization 1.198873e-6
GO:0048545 response to steroid hormone stimulus 1.271722e-6
GO:0006434 seryl-tRNA aminoacylation 1.322871e-6
GO:0001938 positive regulation of endothelial cell proliferation 1.344315e-6
GO:0016477 cell migration 1.345241e-6
GO:0001933 negative regulation of protein phosphorylation 1.367428e-6
GO:0043269 regulation of ion transport 1.431798e-6
GO:0048584 positive regulation of response to stimulus 1.436850e-6
GO:0090031 positive regulation of steroid hormone biosynthetic process 1.451015e-6
GO:2000145 regulation of cell motility 1.456862e-6
GO:0007584 response to nutrient 1.479433e-6
GO:0044281 small molecule metabolic process 1.505428e-6
GO:0031100 organ regeneration 1.525444e-6
GO:0032350 regulation of hormone metabolic process 1.528174e-6
GO:0042592 homeostatic process 1.534686e-6
GO:0032352 positive regulation of hormone metabolic process 1.567895e-6
GO:0002237 response to molecule of bacterial origin 1.592345e-6
GO:0046394 carboxylic acid biosynthetic process 1.634184e-6
GO:0055009 atrial cardiac muscle tissue morphogenesis 1.810205e-6
GO:0009628 response to abiotic stimulus 1.810982e-6
GO:0009607 response to biotic stimulus 1.812281e-6
GO:0035089 establishment of apical/basal cell polarity 1.885397e-6
GO:0031400 negative regulation of protein modification process 1.907150e-6
GO:0002682 regulation of immune system process 1.985740e-6
GO:0051270 regulation of cellular component movement 2.015663e-6
GO:0010893 positive regulation of steroid biosynthetic process 2.018368e-6
GO:0014912 negative regulation of smooth muscle cell migration 2.034663e-6
GO:0019217 regulation of fatty acid metabolic process 2.051044e-6
GO:0022409 positive regulation of cell-cell adhesion 2.075796e-6
GO:0051131 chaperone-mediated protein complex assembly 2.083291e-6
GO:0007598 blood coagulation, extrinsic pathway 2.122377e-6
GO:0071529 cementum mineralization 2.290878e-6
GO:0010800 positive regulation of peptidyl-threonine phosphorylation 2.382076e-6
GO:0061061 muscle structure development 2.391491e-6
GO:0007569 cell aging 2.487270e-6
GO:0014067 negative regulation of phosphatidylinositol 3-kinase cascade 2.540769e-6
GO:0071353 cellular response to interleukin-4 2.675812e-6
GO:0022408 negative regulation of cell-cell adhesion 2.725593e-6
GO:0032530 regulation of microvillus organization 2.741678e-6
GO:0046677 response to antibiotic 2.790883e-6
GO:0018894 dibenzo-p-dioxin metabolic process 2.879318e-6
GO:0007059 chromosome segregation 3.105629e-6
GO:0031947 negative regulation of glucocorticoid biosynthetic process 3.179095e-6
GO:0051239 regulation of multicellular organismal process 3.221028e-6
GO:0045066 regulatory T cell differentiation 3.246329e-6
GO:0009566 fertilization 3.369314e-6
GO:0030334 regulation of cell migration 3.397422e-6
GO:0016598 protein arginylation 3.499919e-6
GO:0006883 cellular sodium ion homeostasis 3.723097e-6
GO:0001738 morphogenesis of a polarized epithelium 3.842907e-6
GO:0006066 alcohol metabolic process 4.287965e-6
GO:0032787 monocarboxylic acid metabolic process 4.351686e-6
GO:0016125 sterol metabolic process 4.386165e-6
GO:0006725 cellular aromatic compound metabolic process 4.475272e-6
GO:0022600 digestive system process 4.532027e-6
GO:0002688 regulation of leukocyte chemotaxis 4.542754e-6
GO:0080134 regulation of response to stress 4.684464e-6
GO:0044106 cellular amine metabolic process 4.881420e-6
GO:0045321 leukocyte activation 4.898410e-6
GO:0071320 cellular response to cAMP 5.044579e-6
GO:0051930 regulation of sensory perception of pain 5.109824e-6
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 5.263392e-6
GO:0060137 maternal process involved in parturition 5.286034e-6
GO:0032431 activation of phospholipase A2 activity 5.836550e-6
GO:0071347 cellular response to interleukin-1 6.286215e-6
GO:0051303 establishment of chromosome localization 6.390409e-6
GO:0070887 cellular response to chemical stimulus 6.767692e-6
GO:0034446 substrate adhesion-dependent cell spreading 6.806651e-6
GO:0019953 sexual reproduction 6.931364e-6
GO:0032496 response to lipopolysaccharide 7.044512e-6
GO:0019538 protein metabolic process 7.167898e-6
GO:2000098 negative regulation of smooth muscle cell-matrix adhesion 7.616036e-6
GO:0071258 cellular response to gravity 7.616036e-6
GO:0035491 positive regulation of leukotriene production involved in inflammatory response 7.616036e-6
GO:0061044 negative regulation of vascular wound healing 7.616036e-6
GO:0048729 tissue morphogenesis 7.884114e-6
GO:0032353 negative regulation of hormone biosynthetic process 7.972770e-6
GO:0006414 translational elongation 8.294311e-6
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 8.301483e-6
GO:0061010 gall bladder development 8.343654e-6
GO:0048610 cellular process involved in reproduction 8.589088e-6
GO:0048002 antigen processing and presentation of peptide antigen 8.630759e-6
GO:0009308 amine metabolic process 8.657878e-6
GO:0046717 acid secretion 8.670153e-6
GO:0045123 cellular extravasation 8.747565e-6
GO:0001817 regulation of cytokine production 9.036529e-6
GO:0031667 response to nutrient levels 9.261716e-6
GO:0060676 ureteric bud formation 9.285959e-6
GO:0035684 helper T cell extravasation 9.501758e-6
GO:0010827 regulation of glucose transport 9.548065e-6
GO:0051295 establishment of meiotic spindle localization 9.677636e-6
GO:0050920 regulation of chemotaxis 9.926406e-6
GO:0003209 cardiac atrium morphogenesis 1.015666e-5
GO:0050776 regulation of immune response 1.088499e-5
GO:0010575 positive regulation vascular endothelial growth factor production 1.132561e-5
GO:0015760 glucose-6-phosphate transport 1.177895e-5
GO:0045834 positive regulation of lipid metabolic process 1.197320e-5
GO:0032425 positive regulation of mismatch repair 1.236416e-5
GO:0002684 positive regulation of immune system process 1.241114e-5
GO:0008284 positive regulation of cell proliferation 1.286447e-5
GO:0006956 complement activation 1.333108e-5
GO:0031023 microtubule organizing center organization 1.378024e-5
GO:0006629 lipid metabolic process 1.383342e-5
GO:0019725 cellular homeostasis 1.406718e-5
GO:0048146 positive regulation of fibroblast proliferation 1.465530e-5
GO:0030277 maintenance of gastrointestinal epithelium 1.501079e-5
GO:0051241 negative regulation of multicellular organismal process 1.523404e-5
GO:0015705 iodide transport 1.576607e-5
GO:0008202 steroid metabolic process 1.593993e-5
GO:0051130 positive regulation of cellular component organization 1.728894e-5
GO:0002685 regulation of leukocyte migration 1.734391e-5
GO:0033630 positive regulation of cell adhesion mediated by integrin 1.741789e-5
GO:2000679 positive regulation of transcription regulatory region DNA binding 1.876346e-5
GO:0007132 meiotic metaphase I 1.912751e-5
GO:0050911 detection of chemical stimulus involved in sensory perception of smell 1.920640e-5
GO:0033566 gamma-tubulin complex localization 1.938114e-5
GO:0002250 adaptive immune response 1.940258e-5
GO:0051186 cofactor metabolic process 1.940548e-5
GO:0006907 pinocytosis 1.949325e-5
GO:0003009 skeletal muscle contraction 1.977581e-5
GO:0009156 ribonucleoside monophosphate biosynthetic process 1.987097e-5
GO:0050801 ion homeostasis 2.015417e-5
GO:0044255 cellular lipid metabolic process 2.064881e-5
GO:0002274 myeloid leukocyte activation 2.118977e-5
GO:0006732 coenzyme metabolic process 2.132495e-5
GO:0034661 ncRNA catabolic process 2.206806e-5
GO:0048247 lymphocyte chemotaxis 2.207439e-5
GO:0015980 energy derivation by oxidation of organic compounds 2.290471e-5
GO:0050714 positive regulation of protein secretion 2.295291e-5
GO:0007155 cell adhesion 2.396478e-5
GO:0051054 positive regulation of DNA metabolic process 2.405375e-5
GO:0009437 carnitine metabolic process 2.442452e-5
GO:0022407 regulation of cell-cell adhesion 2.519562e-5
GO:0001554 luteolysis 2.596597e-5
GO:0042758 long-chain fatty acid catabolic process 2.618905e-5
GO:0042413 carnitine catabolic process 2.618905e-5
GO:0006775 fat-soluble vitamin metabolic process 2.649227e-5
GO:0050708 regulation of protein secretion 2.746562e-5
GO:0044057 regulation of system process 2.877469e-5
GO:0030859 polarized epithelial cell differentiation 2.947402e-5
GO:0042177 negative regulation of protein catabolic process 2.960630e-5
GO:0055078 sodium ion homeostasis 3.006257e-5
GO:0061011 hepatic duct development 3.008953e-5
GO:0044283 small molecule biosynthetic process 3.051870e-5
GO:0019370 leukotriene biosynthetic process 3.069691e-5
GO:0010623 developmental programmed cell death 3.223871e-5
GO:0050806 positive regulation of synaptic transmission 3.255428e-5
GO:0035058 nonmotile primary cilium assembly 3.267222e-5
GO:0009191 ribonucleoside diphosphate catabolic process 3.451479e-5
GO:0022402 cell cycle process 3.453576e-5
GO:0010595 positive regulation of endothelial cell migration 3.489491e-5
GO:0035881 amacrine cell differentiation 3.549962e-5
GO:0016064 immunoglobulin mediated immune response 3.567206e-5
GO:0009895 negative regulation of catabolic process 3.750217e-5
GO:0033993 response to lipid 3.792981e-5
GO:0051240 positive regulation of multicellular organismal process 3.894426e-5
GO:0010621 negative regulation of transcription by transcription factor localization 3.894716e-5
GO:0048609 multicellular organismal reproductive process 4.081238e-5
GO:0048878 chemical homeostasis 4.095621e-5
GO:0051591 response to cAMP 4.108424e-5
GO:0048742 regulation of skeletal muscle fiber development 4.458017e-5
GO:0070145 mitochondrial asparaginyl-tRNA aminoacylation 4.467680e-5
GO:0007166 cell surface receptor linked signaling pathway 4.515406e-5
GO:0006996 organelle organization 4.539697e-5
GO:0010565 regulation of cellular ketone metabolic process 4.669351e-5
GO:0021543 pallium development 4.715236e-5
GO:0034696 response to prostaglandin F stimulus 4.847882e-5
GO:0070543 response to linoleic acid 4.847882e-5
GO:0035105 sterol regulatory element binding protein import into nucleus 4.874828e-5
GO:0060070 canonical Wnt receptor signaling pathway 4.920993e-5
GO:0048583 regulation of response to stimulus 4.968180e-5
GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway 4.986496e-5
GO:0031960 response to corticosteroid stimulus 5.212494e-5
GO:0035883 enteroendocrine cell differentiation 5.266240e-5
GO:0032429 regulation of phospholipase A2 activity 5.362897e-5
GO:0007320 insemination 5.415758e-5
GO:0050793 regulation of developmental process 5.479492e-5
GO:0048627 myoblast development 5.485245e-5
GO:0015920 lipopolysaccharide transport 5.485245e-5
GO:0051384 response to glucocorticoid stimulus 5.486483e-5
GO:0008203 cholesterol metabolic process 5.590101e-5
GO:0048589 developmental growth 5.680486e-5
GO:0016310 phosphorylation 5.700892e-5
GO:0006958 complement activation, classical pathway 5.729117e-5
GO:0006091 generation of precursor metabolites and energy 5.767236e-5
GO:0032534 regulation of microvillus assembly 5.774713e-5
GO:0030317 sperm motility 5.803242e-5
GO:0007608 sensory perception of smell 6.153929e-5
GO:0042254 ribosome biogenesis 6.157078e-5
GO:0034111 negative regulation of homotypic cell-cell adhesion 6.299461e-5
GO:0046426 negative regulation of JAK-STAT cascade 6.352919e-5
GO:0015698 inorganic anion transport 6.487011e-5
GO:0009161 ribonucleoside monophosphate metabolic process 6.564702e-5
GO:0090068 positive regulation of cell cycle process 6.886660e-5
GO:0071158 positive regulation of cell cycle arrest 6.979427e-5
GO:0018904 organic ether metabolic process 7.019572e-5
GO:0014061 regulation of norepinephrine secretion 7.028518e-5
GO:0044241 lipid digestion 7.085070e-5
GO:0007162 negative regulation of cell adhesion 7.159469e-5
GO:0032673 regulation of interleukin-4 production 7.162090e-5
GO:0033036 macromolecule localization 7.380074e-5
GO:0016337 cell-cell adhesion 7.483135e-5
GO:0046031 ADP metabolic process 7.770009e-5
GO:0032963 collagen metabolic process 7.787906e-5
GO:0006144 purine base metabolic process 7.787906e-5
GO:0007606 sensory perception of chemical stimulus 7.835026e-5
GO:0016072 rRNA metabolic process 7.852404e-5
GO:0002690 positive regulation of leukocyte chemotaxis 7.857545e-5
GO:0071379 cellular response to prostaglandin stimulus 7.929590e-5
GO:0060157 urinary bladder development 8.017328e-5
GO:0048856 anatomical structure development 8.047243e-5
GO:0044259 multicellular organismal macromolecule metabolic process 8.331500e-5
GO:0051725 protein de-ADP-ribosylation 8.387580e-5
GO:0051409 response to nitrosative stress 8.398305e-5
GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback 8.454044e-5
GO:0045833 negative regulation of lipid metabolic process 8.548716e-5
GO:0050866 negative regulation of cell activation 8.687131e-5
GO:0002455 humoral immune response mediated by circulating immunoglobulin 8.701992e-5
GO:0009448 gamma-aminobutyric acid metabolic process 8.752222e-5
GO:0006820 anion transport 8.910488e-5
GO:0006109 regulation of carbohydrate metabolic process 8.911166e-5
GO:0032502 developmental process 9.200270e-5
GO:0050795 regulation of behavior 9.293408e-5
GO:0050865 regulation of cell activation 9.406338e-5
GO:0006700 C21-steroid hormone biosynthetic process 9.433068e-5
GO:0019882 antigen processing and presentation 9.537799e-5
GO:0051454 intracellular pH elevation 9.605597e-5
GO:0060571 morphogenesis of an epithelial fold 9.649592e-5
GO:0032430 positive regulation of phospholipase A2 activity 9.667791e-5
GO:0048585 negative regulation of response to stimulus 9.753968e-5
GO:0006690 icosanoid metabolic process 9.782811e-5
GO:0060730 regulation of intestinal epithelial structure maintenance 9.788440e-5
GO:0051128 regulation of cellular component organization 9.860353e-5
GO:0007586 digestion 1.025496e-4
GO:0009060 aerobic respiration 1.057260e-4
GO:0060992 response to fungicide 1.069661e-4
GO:0050482 arachidonic acid secretion 1.086765e-4
GO:0043623 cellular protein complex assembly 1.098939e-4
GO:0071715 icosanoid transport 1.127092e-4
GO:0002687 positive regulation of leukocyte migration 1.144221e-4
GO:0030186 melatonin metabolic process 1.162602e-4
GO:0030195 negative regulation of blood coagulation 1.164682e-4
GO:0022607 cellular component assembly 1.184716e-4
GO:0006508 proteolysis 1.186394e-4
GO:0007568 aging 1.205186e-4
GO:0055114 oxidation-reduction process 1.216672e-4
GO:0071840 cellular component organization or biogenesis 1.245631e-4
GO:0046320 regulation of fatty acid oxidation 1.246732e-4
GO:0018879 biphenyl metabolic process 1.330579e-4
GO:0018963 phthalate metabolic process 1.387415e-4
GO:0071214 cellular response to abiotic stimulus 1.398993e-4
GO:0051790 short-chain fatty acid biosynthetic process 1.417246e-4
GO:0033559 unsaturated fatty acid metabolic process 1.453700e-4
GO:0006873 cellular ion homeostasis 1.479930e-4
GO:2000097 regulation of smooth muscle cell-matrix adhesion 1.480196e-4
GO:0034014 response to triglyceride 1.504441e-4
GO:0010669 epithelial structure maintenance 1.525639e-4
GO:0006691 leukotriene metabolic process 1.531275e-4
GO:0010701 positive regulation of norepinephrine secretion 1.565918e-4
GO:0006767 water-soluble vitamin metabolic process 1.594719e-4
GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin 1.594931e-4
GO:0043069 negative regulation of programmed cell death 1.599669e-4
GO:0002720 positive regulation of cytokine production involved in immune response 1.610155e-4
GO:0050966 detection of mechanical stimulus involved in sensory perception of pain 1.629243e-4
GO:0009605 response to external stimulus 1.632239e-4
GO:0043066 negative regulation of apoptosis 1.668298e-4
GO:0006721 terpenoid metabolic process 1.670589e-4
GO:0007049 cell cycle 1.694081e-4
GO:0009991 response to extracellular stimulus 1.720006e-4
GO:0043129 surfactant homeostasis 1.814217e-4
GO:0050819 negative regulation of coagulation 1.844479e-4
GO:0010675 regulation of cellular carbohydrate metabolic process 1.851509e-4
GO:0009260 ribonucleotide biosynthetic process 1.852974e-4
GO:0051597 response to methylmercury 1.865176e-4
GO:0030850 prostate gland development 1.874815e-4
GO:0061077 chaperone-mediated protein folding 1.901655e-4
GO:0021987 cerebral cortex development 1.913973e-4
GO:0044403 symbiosis, encompassing mutualism through parasitism 1.930307e-4
GO:0007154 cell communication 1.952508e-4
GO:0045663 positive regulation of myoblast differentiation 1.962558e-4
GO:0002718 regulation of cytokine production involved in immune response 1.989300e-4
GO:0071310 cellular response to organic substance 2.021403e-4
GO:0055082 cellular chemical homeostasis 2.035930e-4
GO:0023056 positive regulation of signaling 2.051294e-4
GO:0006897 endocytosis 2.126271e-4
GO:0090181 regulation of cholesterol metabolic process 2.184707e-4
GO:0008610 lipid biosynthetic process 2.228420e-4
GO:0042246 tissue regeneration 2.270863e-4
GO:0010647 positive regulation of cell communication 2.309268e-4
GO:0009449 gamma-aminobutyric acid biosynthetic process 2.315927e-4
GO:0060548 negative regulation of cell death 2.336723e-4
GO:0007512 adult heart development 2.341060e-4
GO:2000677 regulation of transcription regulatory region DNA binding 2.352719e-4
GO:0008643 carbohydrate transport 2.372012e-4
GO:0010646 regulation of cell communication 2.379256e-4
GO:0009887 organ morphogenesis 2.435888e-4
GO:0023052 signaling 2.438470e-4
GO:0010959 regulation of metal ion transport 2.503799e-4
GO:0001934 positive regulation of protein phosphorylation 2.517504e-4
GO:0042742 defense response to bacterium 2.524880e-4
GO:0009268 response to pH 2.551218e-4
GO:0009069 serine family amino acid metabolic process 2.627064e-4
GO:0009071 serine family amino acid catabolic process 2.627841e-4
GO:0021509 roof plate formation 2.633357e-4
GO:0000212 meiotic spindle organization 2.635404e-4
GO:0060461 right lung morphogenesis 2.647389e-4
GO:0060446 branching involved in open tracheal system development 2.647389e-4
GO:0090131 mesenchyme migration 2.647389e-4


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0044259 multicellular organismal macromolecule metabolic process 4.900695e-13
GO:0032963 collagen metabolic process 6.421865e-13
GO:0045653 negative regulation of megakaryocyte differentiation 3.820412e-12
GO:0044236 multicellular organismal metabolic process 1.292873e-11
GO:0070208 protein heterotrimerization 2.074213e-11
GO:0050953 sensory perception of light stimulus 1.548633e-10
GO:0007601 visual perception 1.744704e-10
GO:0031667 response to nutrient levels 2.547847e-10
GO:0009991 response to extracellular stimulus 6.233621e-10
GO:0007600 sensory perception 7.762988e-10
GO:0010269 response to selenium ion 1.359881e-8
GO:0007584 response to nutrient 1.411755e-8
GO:0003008 system process 2.070954e-8
GO:0000072 M phase specific microtubule process 2.231289e-8
GO:0030574 collagen catabolic process 2.270191e-8
GO:0070206 protein trimerization 2.816154e-8
GO:0006936 muscle contraction 3.233159e-8
GO:0009607 response to biotic stimulus 3.238890e-8
GO:0019221 cytokine-mediated signaling pathway 4.554606e-8
GO:0000302 response to reactive oxygen species 1.583828e-7
GO:0032792 negative regulation of CREB transcription factor activity 2.013188e-7
GO:0031960 response to corticosteroid stimulus 2.128246e-7
GO:0045085 negative regulation of interleukin-2 biosynthetic process 2.617630e-7
GO:0030573 bile acid catabolic process 2.713836e-7
GO:0002252 immune effector process 3.344054e-7
GO:0071345 cellular response to cytokine stimulus 3.495984e-7
GO:0007021 tubulin complex assembly 4.131591e-7
GO:0090074 negative regulation of protein homodimerization activity 4.211782e-7
GO:0009303 rRNA transcription 5.118498e-7
GO:0071396 cellular response to lipid 5.330094e-7
GO:0060828 regulation of canonical Wnt receptor signaling pathway 5.779575e-7
GO:0034374 low-density lipoprotein particle remodeling 8.978616e-7
GO:0090263 positive regulation of canonical Wnt receptor signaling pathway 1.024001e-6
GO:0060561 apoptosis involved in morphogenesis 1.061905e-6
GO:0010035 response to inorganic substance 1.118294e-6
GO:0071300 cellular response to retinoic acid 1.268932e-6
GO:0003012 muscle system process 1.367977e-6
GO:0071299 cellular response to vitamin A 1.558463e-6
GO:0044242 cellular lipid catabolic process 1.654387e-6
GO:0051707 response to other organism 1.684570e-6
GO:0045540 regulation of cholesterol biosynthetic process 1.971976e-6
GO:0035094 response to nicotine 2.079770e-6
GO:0050877 neurological system process 2.196279e-6
GO:0071379 cellular response to prostaglandin stimulus 2.279825e-6
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis 2.828429e-6
GO:0032966 negative regulation of collagen biosynthetic process 4.201388e-6
GO:0045721 negative regulation of gluconeogenesis 4.213707e-6
GO:0032964 collagen biosynthetic process 4.553031e-6
GO:0009743 response to carbohydrate stimulus 4.739628e-6
GO:0032501 multicellular organismal process 4.777482e-6
GO:0030199 collagen fibril organization 4.934243e-6
GO:0072333 signal transduction by p53 class mediator resulting in induction of anoikis 5.127757e-6
GO:0044243 multicellular organismal catabolic process 5.244794e-6
GO:0055002 striated muscle cell development 5.754138e-6
GO:2000209 regulation of anoikis 5.939543e-6
GO:0010770 positive regulation of cell morphogenesis involved in differentiation 6.080874e-6
GO:0033189 response to vitamin A 6.110530e-6
GO:0009185 ribonucleoside diphosphate metabolic process 7.075758e-6
GO:0090181 regulation of cholesterol metabolic process 7.278884e-6
GO:0043434 response to peptide hormone stimulus 7.488645e-6
GO:0009612 response to mechanical stimulus 8.140235e-6
GO:0007346 regulation of mitotic cell cycle 9.681888e-6
GO:0071295 cellular response to vitamin 1.047253e-5
GO:0033273 response to vitamin 1.202503e-5
GO:0030177 positive regulation of Wnt receptor signaling pathway 1.266828e-5
GO:0009395 phospholipid catabolic process 1.282969e-5
GO:0019285 glycine betaine biosynthetic process from choline 1.370413e-5
GO:0002443 leukocyte mediated immunity 1.445782e-5
GO:0048747 muscle fiber development 1.457863e-5
GO:0032355 response to estradiol stimulus 1.462720e-5
GO:0001649 osteoblast differentiation 1.516374e-5
GO:0006952 defense response 1.571308e-5
GO:0070474 positive regulation of uterine smooth muscle contraction 1.585896e-5
GO:0007320 insemination 1.680591e-5
GO:0019374 galactolipid metabolic process 1.715028e-5
GO:0072087 renal vesicle development 2.090217e-5
GO:0090049 regulation of cell migration involved in sprouting angiogenesis 2.120418e-5
GO:0010193 response to ozone 2.159499e-5
GO:0042542 response to hydrogen peroxide 2.418987e-5
GO:0001558 regulation of cell growth 2.577891e-5
GO:2000210 positive regulation of anoikis 2.666394e-5
GO:0009145 purine nucleoside triphosphate biosynthetic process 2.746559e-5
GO:0045589 regulation of regulatory T cell differentiation 2.841730e-5
GO:0019371 cyclooxygenase pathway 3.043178e-5
GO:0002456 T cell mediated immunity 3.101084e-5
GO:0009206 purine ribonucleoside triphosphate biosynthetic process 3.197835e-5
GO:0009134 nucleoside diphosphate catabolic process 3.265558e-5
GO:0002679 respiratory burst involved in defense response 3.320154e-5
GO:0072668 tubulin complex biogenesis 3.381637e-5
GO:0051704 multi-organism process 3.445982e-5
GO:0032965 regulation of collagen biosynthetic process 3.518468e-5
GO:0000003 reproduction 3.565902e-5
GO:0009201 ribonucleoside triphosphate biosynthetic process 3.593038e-5
GO:0006754 ATP biosynthetic process 3.744706e-5
GO:0090403 oxidative stress-induced premature senescence 3.759974e-5
GO:0032526 response to retinoic acid 3.909427e-5
GO:0008306 associative learning 4.003575e-5
GO:0007620 copulation 4.100198e-5
GO:0006979 response to oxidative stress 4.117467e-5
GO:0046890 regulation of lipid biosynthetic process 4.225436e-5
GO:0022007 convergent extension involved in neural plate elongation 4.460402e-5
GO:0055001 muscle cell development 4.556611e-5
GO:0031670 cellular response to nutrient 4.765343e-5
GO:0051384 response to glucocorticoid stimulus 4.766811e-5
GO:0045918 negative regulation of cytolysis 4.854911e-5
GO:0060029 convergent extension involved in organogenesis 5.184548e-5
GO:0044246 regulation of multicellular organismal metabolic process 5.304923e-5
GO:0007164 establishment of tissue polarity 5.309266e-5
GO:0048668 collateral sprouting 5.366826e-5
GO:0051146 striated muscle cell differentiation 5.981952e-5
GO:0002792 negative regulation of peptide secretion 6.022277e-5
GO:0001934 positive regulation of protein phosphorylation 6.029276e-5
GO:0010718 positive regulation of epithelial to mesenchymal transition 6.045212e-5
GO:0034097 response to cytokine stimulus 6.130315e-5
GO:0071340 skeletal muscle nicotinic acetylcholine receptor clustering 6.359296e-5
GO:0060346 bone trabecula formation 6.401461e-5
GO:0010717 regulation of epithelial to mesenchymal transition 6.442866e-5
GO:0002449 lymphocyte mediated immunity 7.155385e-5
GO:0060026 convergent extension 7.569375e-5
GO:0043589 skin morphogenesis 7.599591e-5
GO:0009142 nucleoside triphosphate biosynthetic process 8.331479e-5
GO:0016998 cell wall macromolecule catabolic process 8.713604e-5
GO:0010350 cellular response to magnesium starvation 8.874947e-5
GO:0048311 mitochondrion distribution 9.396174e-5
GO:0045590 negative regulation of regulatory T cell differentiation 9.507551e-5
GO:0010574 regulation of vascular endothelial growth factor production 1.054272e-4
GO:0090361 regulation of platelet-derived growth factor production 1.081992e-4
GO:0045652 regulation of megakaryocyte differentiation 1.096776e-4
GO:0001798 positive regulation of type IIa hypersensitivity 1.110762e-4
GO:0010866 regulation of triglyceride biosynthetic process 1.153410e-4
GO:0050832 defense response to fungus 1.172799e-4
GO:0050810 regulation of steroid biosynthetic process 1.250549e-4
GO:0050896 response to stimulus 1.271076e-4
GO:0045065 cytotoxic T cell differentiation 1.299849e-4
GO:0045747 positive regulation of Notch signaling pathway 1.355555e-4
GO:0060416 response to growth hormone stimulus 1.386221e-4
GO:0051260 protein homooligomerization 1.400342e-4
GO:0009179 purine ribonucleoside diphosphate metabolic process 1.407231e-4
GO:0006957 complement activation, alternative pathway 1.415383e-4
GO:0022414 reproductive process 1.533564e-4
GO:0002149 hypochlorous acid biosynthetic process 1.549562e-4
GO:0006642 triglyceride mobilization 1.549796e-4
GO:0007606 sensory perception of chemical stimulus 1.594560e-4
GO:0009191 ribonucleoside diphosphate catabolic process 1.594773e-4
GO:0001736 establishment of planar polarity 1.641040e-4
GO:0042692 muscle cell differentiation 1.649453e-4
GO:0007512 adult heart development 1.657589e-4
GO:0055114 oxidation-reduction process 1.700275e-4
GO:0071287 cellular response to manganese ion 1.830683e-4
GO:0001969 regulation of activation of membrane attack complex 1.853804e-4
GO:0048563 post-embryonic organ morphogenesis 1.871159e-4
GO:0090336 positive regulation of brown fat cell differentiation 1.883065e-4
GO:0090362 positive regulation of platelet-derived growth factor production 1.883065e-4
GO:0090271 positive regulation of fibroblast growth factor production 1.883065e-4
GO:0050760 negative regulation of thymidylate synthase biosynthetic process 1.883065e-4
GO:0030111 regulation of Wnt receptor signaling pathway 1.883669e-4
GO:0007568 aging 1.908515e-4
GO:0045860 positive regulation of protein kinase activity 1.915239e-4
GO:0010744 positive regulation of macrophage derived foam cell differentiation 1.952058e-4
GO:0061061 muscle structure development 1.972911e-4
GO:0042221 response to chemical stimulus 1.973208e-4
GO:0048545 response to steroid hormone stimulus 2.041463e-4
GO:0015986 ATP synthesis coupled proton transport 2.042661e-4
GO:0090270 regulation of fibroblast growth factor production 2.184854e-4
GO:0043316 cytotoxic T cell degranulation 2.263085e-4
GO:0045076 regulation of interleukin-2 biosynthetic process 2.264977e-4
GO:0070141 response to UV-A 2.291460e-4
GO:0033182 regulation of histone ubiquitination 2.428192e-4
GO:0000379 tRNA-type intron splice site recognition and cleavage 2.428192e-4
GO:0045066 regulatory T cell differentiation 2.446188e-4
GO:0031064 negative regulation of histone deacetylation 2.476171e-4
GO:0002883 regulation of hypersensitivity 2.515436e-4
GO:0003337 mesenchymal to epithelial transition involved in metanephros morphogenesis 2.537439e-4
GO:0002309 T cell proliferation involved in immune response 2.558223e-4
GO:0048013 ephrin receptor signaling pathway 2.574593e-4
GO:0007406 negative regulation of neuroblast proliferation 2.724671e-4
GO:0006334 nucleosome assembly 2.791636e-4
GO:0007586 digestion 2.796571e-4
GO:0034694 response to prostaglandin stimulus 3.066970e-4
GO:0030431 sleep 3.092291e-4
GO:0042713 sperm ejaculation 3.106339e-4
GO:0009620 response to fungus 3.133648e-4
GO:0072332 signal transduction by p53 class mediator resulting in induction of apoptosis 3.197935e-4
GO:0009725 response to hormone stimulus 3.205495e-4
GO:0008340 determination of adult lifespan 3.294504e-4
GO:0032859 activation of Ral GTPase activity 3.374583e-4
GO:0046888 negative regulation of hormone secretion 3.391917e-4
GO:0031424 keratinization 3.633429e-4
GO:0002513 tolerance induction to self antigen 3.667550e-4
GO:0043519 regulation of myosin II filament organization 3.701003e-4
GO:0006699 bile acid biosynthetic process 3.701003e-4
GO:0042104 positive regulation of activated T cell proliferation 3.735745e-4
GO:0070252 actin-mediated cell contraction 3.764355e-4
GO:0033275 actin-myosin filament sliding 3.799782e-4
GO:0050863 regulation of T cell activation 3.878448e-4
GO:0022607 cellular component assembly 3.965966e-4
GO:0090179 planar cell polarity pathway involved in neural tube closure 4.018986e-4
GO:0010033 response to organic substance 4.031784e-4
GO:0031032 actomyosin structure organization 4.052498e-4
GO:0031668 cellular response to extracellular stimulus 4.123527e-4
GO:0030035 microspike assembly 4.124726e-4
GO:0010936 negative regulation of macrophage cytokine production 4.143203e-4
GO:0090192 regulation of glomerulus development 4.229484e-4
GO:0045730 respiratory burst 4.281851e-4
GO:0009750 response to fructose stimulus 4.384419e-4
GO:0050974 detection of mechanical stimulus involved in sensory perception 4.538170e-4
GO:0034505 tooth mineralization 4.607422e-4
GO:0007608 sensory perception of smell 4.638007e-4
GO:0043933 macromolecular complex subunit organization 4.813931e-4
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 4.863662e-4
GO:0055003 cardiac myofibril assembly 4.935369e-4
GO:0019216 regulation of lipid metabolic process 5.126376e-4
GO:0010638 positive regulation of organelle organization 5.144745e-4
GO:0050829 defense response to Gram-negative bacterium 5.174133e-4
GO:0043276 anoikis 5.238384e-4
GO:0033674 positive regulation of kinase activity 5.330124e-4
GO:0070306 lens fiber cell differentiation 5.356468e-4
GO:0030049 muscle filament sliding 5.396750e-4
GO:0050868 negative regulation of T cell activation 5.457713e-4
GO:0010466 negative regulation of peptidase activity 5.461491e-4
GO:0021535 cell migration in hindbrain 5.535749e-4
GO:0050982 detection of mechanical stimulus 5.583302e-4
GO:0071496 cellular response to external stimulus 5.712785e-4
GO:0009605 response to external stimulus 5.715597e-4
GO:0018993 somatic sex determination 5.820755e-4
GO:0001516 prostaglandin biosynthetic process 5.883449e-4
GO:0090278 negative regulation of peptide hormone secretion 5.901345e-4
GO:0032780 negative regulation of ATPase activity 5.939884e-4
GO:0002115 store-operated calcium entry 5.939884e-4
GO:0050954 sensory perception of mechanical stimulus 5.955312e-4
GO:0046676 negative regulation of insulin secretion 6.020904e-4
GO:0001839 neural plate morphogenesis 6.079373e-4
GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 6.283244e-4
GO:0043627 response to estrogen stimulus 6.296085e-4
GO:0060632 regulation of microtubule-based movement 6.344908e-4
GO:0010575 positive regulation vascular endothelial growth factor production 6.461255e-4
GO:0044085 cellular component biogenesis 6.728847e-4
GO:0061005 cell differentiation involved in kidney development 6.740623e-4
GO:0003093 regulation of glomerular filtration 6.832442e-4
GO:0009408 response to heat 6.865615e-4
GO:0001970 positive regulation of activation of membrane attack complex 7.041257e-4
GO:0051259 protein oligomerization 7.103769e-4
GO:0034446 substrate adhesion-dependent cell spreading 7.328193e-4
GO:0061302 smooth muscle cell-matrix adhesion 7.336440e-4
GO:0000237 leptotene 7.336440e-4
GO:0015884 folic acid transport 7.346694e-4
GO:0006289 nucleotide-excision repair 7.403910e-4
GO:0072283 metanephric renal vesicle morphogenesis 7.514288e-4
GO:0046882 negative regulation of follicle-stimulating hormone secretion 7.516942e-4
GO:0007205 activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway 7.637624e-4
GO:0045937 positive regulation of phosphate metabolic process 7.709163e-4
GO:0060762 regulation of branching involved in mammary gland duct morphogenesis 7.730340e-4
GO:0007283 spermatogenesis 7.777966e-4
GO:0006461 protein complex assembly 7.969763e-4
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 7.974183e-4
GO:0043029 T cell homeostasis 8.239059e-4
GO:0009152 purine ribonucleotide biosynthetic process 8.260686e-4
GO:0008333 endosome to lysosome transport 8.275421e-4
GO:0065003 macromolecular complex assembly 8.525637e-4
GO:0031282 regulation of guanylate cyclase activity 8.528684e-4
GO:0042327 positive regulation of phosphorylation 8.533326e-4
GO:0006682 galactosylceramide biosynthetic process 8.701108e-4
GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions 8.701108e-4
GO:0009615 response to virus 8.740706e-4
GO:0031669 cellular response to nutrient levels 9.032665e-4
GO:0032383 regulation of intracellular cholesterol transport 9.136968e-4
GO:0002885 positive regulation of hypersensitivity 9.149383e-4
GO:0072161 mesenchymal cell differentiation involved in kidney development 9.172420e-4
GO:0045603 positive regulation of endothelial cell differentiation 9.186607e-4
GO:0048739 cardiac muscle fiber development 9.433816e-4
GO:0072221 metanephric distal convoluted tubule development 9.528560e-4
GO:0051346 negative regulation of hydrolase activity 9.816635e-4
GO:0072202 cell differentiation involved in metanephros development 9.960133e-4
GO:0060047 heart contraction 1.000654e-3
GO:2000758 positive regulation of peptidyl-lysine acetylation 1.005276e-3
GO:0000733 DNA strand renaturation 1.013104e-3
GO:0072143 mesangial cell development 1.013104e-3
GO:0045930 negative regulation of mitotic cell cycle 1.024519e-3
GO:0006283 transcription-coupled nucleotide-excision repair 1.026255e-3
GO:0019376 galactolipid catabolic process 1.035078e-3
GO:0048541 Peyer's patch development 1.037037e-3
GO:0090343 positive regulation of cell aging 1.064311e-3
GO:0070271 protein complex biogenesis 1.095839e-3
GO:0070741 response to interleukin-6 1.105800e-3
GO:0015980 energy derivation by oxidation of organic compounds 1.106261e-3
GO:0010623 developmental programmed cell death 1.111148e-3
GO:0010830 regulation of myotube differentiation 1.112005e-3
GO:0006164 purine nucleotide biosynthetic process 1.130969e-3
GO:0060039 pericardium development 1.162247e-3
GO:0071822 protein complex subunit organization 1.184017e-3
GO:0030317 sperm motility 1.186874e-3
GO:0045933 positive regulation of muscle contraction 1.196150e-3
GO:0008588 release of cytoplasmic sequestered NF-kappaB 1.217714e-3
GO:0072098 anterior/posterior pattern specification involved in kidney development 1.226682e-3
GO:0048389 intermediate mesoderm development 1.226682e-3
GO:0070498 interleukin-1-mediated signaling pathway 1.236135e-3
GO:0072329 monocarboxylic acid catabolic process 1.248160e-3
GO:0008217 regulation of blood pressure 1.269624e-3
GO:0009101 glycoprotein biosynthetic process 1.273473e-3
GO:0032971 regulation of muscle filament sliding 1.290860e-3
GO:0090030 regulation of steroid hormone biosynthetic process 1.342520e-3
GO:0072422 signal transduction involved in DNA damage checkpoint 1.362651e-3
GO:0042159 lipoprotein catabolic process 1.366239e-3
GO:0001508 regulation of action potential 1.376070e-3
GO:0030252 growth hormone secretion 1.377887e-3
GO:0060324 face development 1.393212e-3
GO:0051705 behavioral interaction between organisms 1.404563e-3
GO:0019049 evasion of host defenses by virus 1.417976e-3
GO:0007522 visceral muscle development 1.429757e-3
GO:0006360 transcription from RNA polymerase I promoter 1.430555e-3
GO:0001840 neural plate development 1.432949e-3
GO:0060325 face morphogenesis 1.448459e-3
GO:0070307 lens fiber cell development 1.450593e-3
GO:0031058 positive regulation of histone modification 1.452053e-3
GO:0030239 myofibril assembly 1.480498e-3
GO:0001967 suckling behavior 1.481166e-3
GO:0072300 positive regulation of metanephric glomerulus development 1.496730e-3
GO:0006631 fatty acid metabolic process 1.600141e-3
GO:0042149 cellular response to glucose starvation 1.605635e-3
GO:0050906 detection of stimulus involved in sensory perception 1.605658e-3
GO:0007618 mating 1.653193e-3
GO:0060071 Wnt receptor signaling pathway, planar cell polarity pathway 1.657369e-3
GO:0030157 pancreatic juice secretion 1.684515e-3
GO:0019369 arachidonic acid metabolic process 1.727613e-3
GO:0006707 cholesterol catabolic process 1.730476e-3
GO:0060685 regulation of prostatic bud formation 1.730476e-3
GO:0006333 chromatin assembly or disassembly 1.736874e-3
GO:0021935 cerebellar granule cell precursor tangential migration 1.748315e-3
GO:0006772 thiamine metabolic process 1.748315e-3
GO:0070207 protein homotrimerization 1.750462e-3
GO:0061360 optic chiasma development 1.804397e-3
GO:2000597 positive regulation of optic nerve formation 1.804397e-3
GO:0035799 ureter maturation 1.804397e-3
GO:0033129 positive regulation of histone phosphorylation 1.804397e-3
GO:0021633 optic nerve structural organization 1.804397e-3
GO:0021650 vestibulocochlear nerve formation 1.804397e-3
GO:0006111 regulation of gluconeogenesis 1.807771e-3
GO:0001957 intramembranous ossification 1.807771e-3
GO:0030854 positive regulation of granulocyte differentiation 1.825606e-3
GO:0035066 positive regulation of histone acetylation 1.844297e-3
GO:0010868 negative regulation of triglyceride biosynthetic process 1.849597e-3
GO:0008015 blood circulation 1.876568e-3
GO:0031063 regulation of histone deacetylation 1.882198e-3
GO:0071731 response to nitric oxide 1.903199e-3
GO:0045668 negative regulation of osteoblast differentiation 1.912633e-3
GO:0022617 extracellular matrix disassembly 1.926043e-3
GO:0042110 T cell activation 1.940410e-3
GO:0042592 homeostatic process 1.943812e-3
GO:0030539 male genitalia development 1.946725e-3
GO:2000178 negative regulation of neural precursor cell proliferation 1.956119e-3
GO:0007154 cell communication 1.959578e-3
GO:0032026 response to magnesium ion 2.014600e-3
GO:0006987 activation of signaling protein activity involved in unfolded protein response 2.037413e-3
GO:0006091 generation of precursor metabolites and energy 2.038322e-3
GO:0021782 glial cell development 2.048009e-3
GO:0034605 cellular response to heat 2.055875e-3
GO:0046031 ADP metabolic process 2.079488e-3
GO:0051046 regulation of secretion 2.102194e-3
GO:0045666 positive regulation of neuron differentiation 2.114247e-3
GO:0045214 sarcomere organization 2.154776e-3
GO:0046034 ATP metabolic process 2.159634e-3
GO:0072077 renal vesicle morphogenesis 2.178319e-3
GO:0051347 positive regulation of transferase activity 2.183273e-3
GO:0006354 transcription elongation, DNA-dependent 2.195044e-3
GO:0009913 epidermal cell differentiation 2.199329e-3
GO:0045077 negative regulation of interferon-gamma biosynthetic process 2.228690e-3
GO:0006540 glutamate decarboxylation to succinate 2.228690e-3
GO:0071827 plasma lipoprotein particle organization 2.235741e-3
GO:0030048 actin filament-based movement 2.256895e-3
GO:0065008 regulation of biological quality 2.283926e-3
GO:0072259 metanephric interstitial cell development 2.312095e-3
GO:0090094 metanephric cap mesenchymal cell proliferation involved in metanephros development 2.312095e-3
GO:2000369 regulation of clathrin-mediated endocytosis 2.312095e-3
GO:0072208 metanephric smooth muscle tissue development 2.312095e-3
GO:0072168 specification of anterior mesonephric tubule identity 2.312095e-3
GO:0072169 specification of posterior mesonephric tubule identity 2.312095e-3
GO:0072184 renal vesicle progenitor cell differentiation 2.312095e-3
GO:0006323 DNA packaging 2.346306e-3
GO:0071636 positive regulation of transforming growth factor beta production 2.355470e-3
GO:0048609 multicellular organismal reproductive process 2.374553e-3
GO:0006958 complement activation, classical pathway 2.385427e-3
GO:0002864 regulation of acute inflammatory response to antigenic stimulus 2.405086e-3
GO:0007566 embryo implantation 2.458492e-3
GO:0030154 cell differentiation 2.506103e-3
GO:0019226 transmission of nerve impulse 2.533054e-3
GO:0010458 exit from mitosis 2.573936e-3
GO:0030216 keratinocyte differentiation 2.652490e-3
GO:0050870 positive regulation of T cell activation 2.680701e-3
GO:0090193 positive regulation of glomerulus development 2.690621e-3
GO:0006578 betaine biosynthetic process 2.690621e-3
GO:0070309 lens fiber cell morphogenesis 2.766630e-3
GO:2000594 positive regulation of metanephric DCT cell differentiation 2.783870e-3
GO:2000384 negative regulation of ectoderm development 2.783870e-3
GO:0039003 pronephric field specification 2.783870e-3
GO:0072305 negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis 2.783870e-3
GO:0007605 sensory perception of sound 2.788540e-3
GO:0030514 negative regulation of BMP signaling pathway 2.830836e-3
GO:0050957 equilibrioception 2.837188e-3
GO:0090311 regulation of protein deacetylation 2.863794e-3
GO:0010038 response to metal ion 2.864549e-3
GO:0042772 DNA damage response, signal transduction resulting in transcription 2.895347e-3
GO:0072017 distal tubule development 2.895672e-3
GO:0010092 specification of organ identity 2.911543e-3
GO:0042840 D-glucuronate catabolic process 2.926330e-3
GO:2001051 positive regulation of tendon cell differentiation 2.926330e-3
GO:0033314 mitotic cell cycle DNA replication checkpoint 2.926330e-3
GO:0051447 negative regulation of meiotic cell cycle 2.926330e-3
GO:0042703 menstruation 2.926330e-3
GO:0032789 unsaturated monocarboxylic acid metabolic process 2.926330e-3
GO:0021509 roof plate formation 2.926330e-3
GO:0019101 female somatic sex determination 2.926330e-3
GO:0032788 saturated monocarboxylic acid metabolic process 2.926330e-3
GO:0033088 negative regulation of immature T cell proliferation in thymus 2.932665e-3
GO:0034383 low-density lipoprotein particle clearance 2.939409e-3
GO:0046466 membrane lipid catabolic process 2.953787e-3
GO:0072522 purine-containing compound biosynthetic process 2.959743e-3
GO:0009260 ribonucleotide biosynthetic process 2.962896e-3
GO:0009132 nucleoside diphosphate metabolic process 2.963520e-3
GO:0060296 regulation of cilium beat frequency involved in ciliary motility 2.970061e-3
GO:0071217 cellular response to external biotic stimulus 2.987140e-3
GO:0070684 seminal clot liquefaction 2.987140e-3
GO:0009617 response to bacterium 2.995257e-3
GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter 3.039011e-3
GO:0090185 negative regulation of kidney development 3.039011e-3
GO:0042249 establishment of planar polarity of embryonic epithelium 3.039011e-3
GO:0016197 endosome transport 3.058479e-3
GO:0033363 secretory granule organization 3.081697e-3
GO:0006643 membrane lipid metabolic process 3.096000e-3
GO:0007166 cell surface receptor linked signaling pathway 3.108242e-3
GO:0019725 cellular homeostasis 3.112358e-3
GO:0003013 circulatory system process 3.113369e-3
GO:0050670 regulation of lymphocyte proliferation 3.189895e-3
GO:0051225 spindle assembly 3.194550e-3
GO:0035235 ionotropic glutamate receptor signaling pathway 3.199829e-3
GO:0000189 MAPK import into nucleus 3.212357e-3
GO:0007096 regulation of exit from mitosis 3.212410e-3
GO:0071732 cellular response to nitric oxide 3.261396e-3
GO:0060019 radial glial cell differentiation 3.269136e-3
GO:0042522 regulation of tyrosine phosphorylation of Stat5 protein 3.269136e-3
GO:0052547 regulation of peptidase activity 3.297164e-3
GO:0032944 regulation of mononuclear cell proliferation 3.303054e-3
GO:0021941 negative regulation of cerebellar granule cell precursor proliferation 3.373600e-3
GO:0002357 defense response to tumor cell 3.373600e-3
GO:0010701 positive regulation of norepinephrine secretion 3.373600e-3
GO:0022010 central nervous system myelination 3.377645e-3
GO:0009181 purine ribonucleoside diphosphate catabolic process 3.396220e-3
GO:0070663 regulation of leukocyte proliferation 3.411319e-3
GO:0042953 lipoprotein transport 3.472788e-3
GO:0002260 lymphocyte homeostasis 3.486089e-3
GO:0046847 filopodium assembly 3.530512e-3
GO:0046716 muscle cell homeostasis 3.564865e-3
GO:0061113 pancreas morphogenesis 3.578655e-3
GO:0010042 response to manganese ion 3.601697e-3
GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development 3.614298e-3
GO:0031129 inductive cell-cell signaling 3.614298e-3
GO:0060259 regulation of feeding behavior 3.698213e-3
GO:0006638 neutral lipid metabolic process 3.698949e-3
GO:0045766 positive regulation of angiogenesis 3.724500e-3
GO:0014049 positive regulation of glutamate secretion 3.733661e-3
GO:0055013 cardiac muscle cell development 3.789035e-3
GO:0070085 glycosylation 3.792347e-3
GO:0003015 heart process 3.793136e-3
GO:0001776 leukocyte homeostasis 3.793136e-3
GO:0009582 detection of abiotic stimulus 3.841348e-3
GO:0008366 axon ensheathment 3.885258e-3
GO:0014070 response to organic cyclic compound 3.887554e-3
GO:0072162 metanephric mesenchymal cell differentiation 3.923569e-3
GO:0010954 positive regulation of protein processing 3.973573e-3
GO:0009266 response to temperature stimulus 3.977823e-3
GO:0060992 response to fungicide 4.029935e-3
GO:0072307 regulation of metanephric nephron tubule epithelial cell differentiation 4.075060e-3
GO:0006639 acylglycerol metabolic process 4.079535e-3
GO:0031295 T cell costimulation 4.091410e-3
GO:0042346 positive regulation of NF-kappaB import into nucleus 4.106202e-3
GO:0002250 adaptive immune response 4.127614e-3
GO:0015868 purine ribonucleotide transport 4.161314e-3
GO:0043462 regulation of ATPase activity 4.187163e-3
GO:0002861 regulation of inflammatory response to antigenic stimulus 4.203746e-3
GO:0014074 response to purine-containing compound 4.219310e-3
GO:0051971 positive regulation of transmission of nerve impulse 4.224320e-3
GO:0006172 ADP biosynthetic process 4.229830e-3
GO:0072003 kidney rudiment formation 4.229830e-3
GO:0002791 regulation of peptide secretion 4.267754e-3
GO:0043056 forward locomotion 4.268559e-3
GO:0046006 regulation of activated T cell proliferation 4.288623e-3
GO:0072040 negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis 4.296058e-3
GO:0030091 protein repair 4.296058e-3
GO:0033382 maintenance of granzyme B location in T cell secretory granule 4.296058e-3
GO:0033373 maintenance of protease location in mast cell secretory granule 4.296058e-3
GO:0031497 chromatin assembly 4.297905e-3
GO:0060560 developmental growth involved in morphogenesis 4.304598e-3
GO:0072194 kidney smooth muscle tissue development 4.327138e-3
GO:0046340 diacylglycerol catabolic process 4.327138e-3
GO:0006956 complement activation 4.387002e-3
GO:0010935 regulation of macrophage cytokine production 4.388601e-3
GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus 4.407164e-3
GO:0006950 response to stress 4.509562e-3
GO:0007040 lysosome organization 4.512669e-3
GO:0071103 DNA conformation change 4.610476e-3
GO:0072376 protein activation cascade 4.634305e-3