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Novel motif:117

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name:motif117_SKSNGCGCTSN

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0007195 inhibition of adenylate cyclase activity by dopamine receptor signaling pathway 6.786705e-9
GO:0043503 skeletal muscle fiber adaptation 1.645276e-8
GO:0031442 positive regulation of mRNA 3'-end processing 5.019044e-8
GO:0006768 biotin metabolic process 8.404805e-8
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation 1.522595e-7
GO:0035470 positive regulation of vascular wound healing 2.476867e-7
GO:0009440 cyanate catabolic process 9.379166e-7
GO:0008033 tRNA processing 1.156828e-6
GO:0015878 biotin transport 1.331868e-6
GO:0015887 pantothenate transmembrane transport 1.331868e-6
GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 2.021992e-6
GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin 2.039557e-6
GO:0051898 negative regulation of protein kinase B signaling cascade 3.161718e-6
GO:0010982 regulation of high-density lipoprotein particle clearance 3.182567e-6
GO:0060038 cardiac muscle cell proliferation 3.349383e-6
GO:0006548 histidine catabolic process 4.883903e-6
GO:0050685 positive regulation of mRNA processing 5.244131e-6
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 5.555120e-6
GO:0032383 regulation of intracellular cholesterol transport 6.191724e-6
GO:0042136 neurotransmitter biosynthetic process 6.450758e-6
GO:0002002 regulation of angiotensin levels in blood 7.897887e-6
GO:0031468 nuclear envelope reassembly 8.089306e-6
GO:0055075 potassium ion homeostasis 9.238019e-6
GO:0006884 cell volume homeostasis 9.836570e-6
GO:0048102 autophagic cell death 9.962930e-6
GO:0006420 arginyl-tRNA aminoacylation 1.064954e-5
GO:0035461 vitamin transmembrane transport 1.233034e-5
GO:2000119 negative regulation of sodium-dependent phosphate transport 1.320360e-5
GO:0006268 DNA unwinding involved in replication 1.578898e-5
GO:0060419 heart growth 1.891984e-5
GO:0009264 deoxyribonucleotide catabolic process 1.901196e-5
GO:0048050 post-embryonic eye morphogenesis 2.218397e-5
GO:0018352 protein-pyridoxal-5-phosphate linkage 2.292720e-5
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway 2.469677e-5
GO:0031440 regulation of mRNA 3'-end processing 2.536818e-5
GO:0010225 response to UV-C 2.792563e-5
GO:0043089 positive regulation of Cdc42 GTPase activity 2.898100e-5
GO:0043097 pyrimidine nucleoside salvage 3.143770e-5
GO:0051586 positive regulation of dopamine uptake 3.405032e-5
GO:0070988 demethylation 4.279808e-5
GO:0051534 negative regulation of NFAT protein import into nucleus 4.283097e-5
GO:0010897 negative regulation of triglyceride catabolic process 4.587298e-5
GO:0010987 negative regulation of high-density lipoprotein particle clearance 4.587298e-5
GO:0016577 histone demethylation 4.593668e-5
GO:0010107 potassium ion import 5.097993e-5
GO:0035357 peroxisome proliferator activated receptor signaling pathway 5.739409e-5
GO:0010988 regulation of low-density lipoprotein particle clearance 5.870265e-5
GO:0060177 regulation of angiotensin metabolic process 5.899061e-5
GO:0006348 chromatin silencing at telomere 6.964059e-5
GO:0002071 glandular epithelial cell maturation 6.964059e-5
GO:0060999 positive regulation of dendritic spine development 7.312186e-5
GO:0055017 cardiac muscle tissue growth 8.906034e-5
GO:0050779 RNA destabilization 9.488761e-5
GO:0000724 double-strand break repair via homologous recombination 9.542175e-5
GO:0010984 regulation of lipoprotein particle clearance 1.033063e-4
GO:2000249 regulation of actin cytoskeleton reorganization 1.045644e-4
GO:0021568 rhombomere 2 development 1.152924e-4
GO:0032006 regulation of TOR signaling cascade 1.250712e-4
GO:0090035 positive regulation of cellular chaperone-mediated protein complex assembly 1.272170e-4
GO:0072337 modified amino acid transport 1.334305e-4
GO:0030539 male genitalia development 1.470506e-4
GO:0009304 tRNA transcription 1.522234e-4
GO:0010609 posttranscriptional regulation of gene expression by mRNA localization 1.522904e-4
GO:0061157 mRNA destabilization 1.522904e-4
GO:0002036 regulation of L-glutamate transport 1.560221e-4
GO:0048343 paraxial mesodermal cell fate commitment 1.600097e-4
GO:0001766 membrane raft polarization 1.601699e-4
GO:0007614 short-term memory 1.863058e-4
GO:0032862 activation of Rho GTPase activity 1.896885e-4
GO:0072272 proximal/distal pattern formation involved in metanephric nephron development 1.913483e-4
GO:0042420 dopamine catabolic process 1.938499e-4
GO:0031848 protection from non-homologous end joining at telomere 1.951112e-4
GO:0007379 segment specification 1.995164e-4
GO:0000725 recombinational repair 2.115556e-4
GO:0003326 pancreatic A cell fate commitment 2.161794e-4
GO:0003329 pancreatic PP cell fate commitment 2.161794e-4
GO:0001881 receptor recycling 2.170176e-4
GO:0070198 protein localization to chromosome, telomeric region 2.178836e-4
GO:0000731 DNA synthesis involved in DNA repair 2.205871e-4
GO:0071071 regulation of phospholipid biosynthetic process 2.226533e-4
GO:0022601 menstrual cycle phase 2.271488e-4
GO:0051764 actin crosslink formation 2.299341e-4
GO:0045005 maintenance of fidelity involved in DNA-dependent DNA replication 2.340984e-4
GO:0040015 negative regulation of multicellular organism growth 2.403575e-4
GO:0006482 protein demethylation 2.466053e-4
GO:0006540 glutamate decarboxylation to succinate 2.486651e-4
GO:0042424 catecholamine catabolic process 2.559010e-4
GO:2000786 positive regulation of autophagic vacuole assembly 2.596827e-4
GO:0071585 detoxification of cadmium ion 2.596827e-4
GO:0006778 porphyrin-containing compound metabolic process 2.834153e-4
GO:0072070 loop of Henle development 2.871402e-4
GO:0008272 sulfate transport 3.205815e-4
GO:0009451 RNA modification 3.243246e-4
GO:0034766 negative regulation of ion transmembrane transport 3.305143e-4
GO:0034723 DNA replication-dependent nucleosome organization 3.374492e-4
GO:0055026 negative regulation of cardiac muscle tissue development 3.374492e-4
GO:0071072 negative regulation of phospholipid biosynthetic process 3.448750e-4
GO:0045007 depurination 3.498614e-4
GO:0035356 cellular triglyceride homeostasis 3.498614e-4
GO:0030421 defecation 3.498614e-4
GO:0060430 lung saccule development 3.852040e-4
GO:0002357 defense response to tumor cell 3.853600e-4
GO:0045922 negative regulation of fatty acid metabolic process 3.880299e-4
GO:0007051 spindle organization 4.107491e-4
GO:0031558 induction of apoptosis in response to chemical stimulus 4.110167e-4
GO:0072086 specification of loop of Henle identity 4.111608e-4
GO:0071732 cellular response to nitric oxide 4.201713e-4
GO:0001946 lymphangiogenesis 4.332659e-4
GO:0006544 glycine metabolic process 4.821120e-4
GO:0031297 replication fork processing 5.125223e-4
GO:0051013 microtubule severing 5.196934e-4
GO:0070194 synaptonemal complex disassembly 5.219883e-4
GO:0044088 regulation of vacuole organization 5.219883e-4
GO:0031662 positive regulation of cyclin-dependent protein kinase activity involved in G2/M 5.219883e-4
GO:0045217 cell-cell junction maintenance 5.288544e-4
GO:0007288 sperm axoneme assembly 5.331109e-4
GO:0032312 regulation of ARF GTPase activity 5.439897e-4
GO:0006449 regulation of translational termination 5.679539e-4
GO:0006261 DNA-dependent DNA replication 5.884655e-4
GO:0048752 semicircular canal morphogenesis 5.982135e-4
GO:0006400 tRNA modification 6.111108e-4
GO:0051532 regulation of NFAT protein import into nucleus 6.671738e-4
GO:0006529 asparagine biosynthetic process 7.111688e-4
GO:0051181 cofactor transport 7.138749e-4
GO:0019264 glycine biosynthetic process from serine 7.227826e-4
GO:0090002 establishment of protein localization in plasma membrane 7.441672e-4
GO:0033013 tetrapyrrole metabolic process 7.560541e-4
GO:0000093 mitotic telophase 7.606177e-4
GO:0048561 establishment of organ orientation 7.678643e-4
GO:0015886 heme transport 7.750291e-4
GO:0045794 negative regulation of cell volume 7.910164e-4
GO:0006285 base-excision repair, AP site formation 7.972776e-4
GO:0042069 regulation of catecholamine metabolic process 8.950183e-4
GO:0032007 negative regulation of TOR signaling cascade 8.969008e-4
GO:0043088 regulation of Cdc42 GTPase activity 9.016631e-4
GO:0031936 negative regulation of chromatin silencing 9.025188e-4
GO:0031507 heterochromatin formation 9.296857e-4
GO:0009258 10-formyltetrahydrofolate catabolic process 9.403938e-4
GO:0046134 pyrimidine nucleoside biosynthetic process 9.824927e-4
GO:0030579 ubiquitin-dependent SMAD protein catabolic process 1.039055e-3
GO:0048627 myoblast development 1.086475e-3
GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery 1.102818e-3
GO:0043973 histone H3-K4 acetylation 1.102818e-3
GO:0046985 positive regulation of hemoglobin biosynthetic process 1.102818e-3
GO:0006478 peptidyl-tyrosine sulfation 1.102818e-3
GO:0042417 dopamine metabolic process 1.112787e-3
GO:0032864 activation of Cdc42 GTPase activity 1.149051e-3
GO:0090398 cellular senescence 1.165228e-3
GO:0018993 somatic sex determination 1.191081e-3
GO:0010719 negative regulation of epithelial to mesenchymal transition 1.196699e-3
GO:0045945 positive regulation of transcription from RNA polymerase III promoter 1.197706e-3
GO:0090307 spindle assembly involved in mitosis 1.212448e-3
GO:0007182 common-partner SMAD protein phosphorylation 1.215182e-3
GO:0000413 protein peptidyl-prolyl isomerization 1.215538e-3
GO:0061003 positive regulation of dendritic spine morphogenesis 1.223476e-3
GO:0014888 striated muscle adaptation 1.238872e-3
GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin 1.394915e-3
GO:0010735 positive regulation of transcription via serum response element binding 1.400065e-3
GO:0033002 muscle cell proliferation 1.451244e-3
GO:0010835 regulation of protein ADP-ribosylation 1.468991e-3
GO:0046684 response to pyrethroid 1.488747e-3
GO:0090281 negative regulation of calcium ion import 1.515238e-3
GO:0071584 negative regulation of zinc ion import 1.515238e-3
GO:0031627 telomeric loop formation 1.515238e-3
GO:0051324 prophase 1.626483e-3
GO:0090303 positive regulation of wound healing 1.691402e-3
GO:0060969 negative regulation of gene silencing 1.716744e-3
GO:0043174 nucleoside salvage 1.760325e-3
GO:0002523 leukocyte migration involved in inflammatory response 1.765604e-3
GO:0031118 rRNA pseudouridine synthesis 1.812085e-3
GO:0014908 myotube differentiation involved in skeletal muscle regeneration 1.812085e-3
GO:0009155 purine deoxyribonucleotide catabolic process 1.856342e-3
GO:0032615 interleukin-12 production 1.859958e-3
GO:0031055 chromatin remodeling at centromere 1.874556e-3
GO:0070368 positive regulation of hepatocyte differentiation 1.894111e-3
GO:0046015 regulation of transcription by glucose 1.898767e-3
GO:0003360 brainstem development 1.915377e-3
GO:0045112 integrin biosynthetic process 1.952282e-3
GO:0042168 heme metabolic process 2.011926e-3
GO:0006760 folic acid-containing compound metabolic process 2.162298e-3
GO:0060338 regulation of type I interferon-mediated signaling pathway 2.167662e-3
GO:0071104 response to interleukin-9 2.233786e-3
GO:0042942 D-serine transport 2.233786e-3
GO:0002418 immune response to tumor cell 2.233786e-3
GO:0032863 activation of Rac GTPase activity 2.234669e-3
GO:0090344 negative regulation of cell aging 2.239346e-3
GO:0042133 neurotransmitter metabolic process 2.266482e-3
GO:0034776 response to histamine 2.297422e-3
GO:0071422 succinate transmembrane transport 2.297422e-3
GO:0007398 ectoderm development 2.303113e-3
GO:0006359 regulation of transcription from RNA polymerase III promoter 2.321835e-3
GO:0045660 positive regulation of neutrophil differentiation 2.340964e-3
GO:0031365 N-terminal protein amino acid modification 2.416631e-3
GO:0071956 cellular component maintenance at cellular level 2.417268e-3
GO:0042506 tyrosine phosphorylation of Stat5 protein 2.438314e-3
GO:0007386 compartment pattern specification 2.495000e-3
GO:0043542 endothelial cell migration 2.507081e-3
GO:0042053 regulation of dopamine metabolic process 2.515293e-3
GO:0006244 pyrimidine nucleotide catabolic process 2.538481e-3
GO:0006779 porphyrin-containing compound biosynthetic process 2.547579e-3
GO:0090141 positive regulation of mitochondrial fission 2.555478e-3
GO:0051590 positive regulation of neurotransmitter transport 2.559548e-3
GO:0070544 histone H3-K36 demethylation 2.577188e-3
GO:0031935 regulation of chromatin silencing 2.609095e-3
GO:0080111 DNA demethylation 2.609095e-3
GO:0031999 negative regulation of fatty acid beta-oxidation 2.649009e-3
GO:0060381 positive regulation of single-stranded telomeric DNA binding 2.649009e-3
GO:0006391 transcription initiation from mitochondrial promoter 2.649009e-3
GO:0042538 hyperosmotic salinity response 2.672517e-3
GO:0045948 positive regulation of translational initiation 2.710542e-3
GO:0010511 regulation of phosphatidylinositol biosynthetic process 2.711054e-3
GO:0051645 Golgi localization 2.752627e-3
GO:0045064 T-helper 2 cell differentiation 2.752627e-3
GO:0002315 marginal zone B cell differentiation 2.752627e-3
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 2.775581e-3
GO:0033602 negative regulation of dopamine secretion 2.815452e-3
GO:0014034 neural crest cell fate commitment 2.818892e-3
GO:0070327 thyroid hormone transport 2.830661e-3
GO:0060580 ventral spinal cord interneuron fate determination 2.965297e-3
GO:0046984 regulation of hemoglobin biosynthetic process 2.965297e-3
GO:0003327 type B pancreatic cell fate commitment 2.965297e-3
GO:0030903 notochord development 3.038644e-3
GO:0000072 M phase specific microtubule process 3.068995e-3
GO:0032319 regulation of Rho GTPase activity 3.123132e-3
GO:0003310 pancreatic A cell differentiation 3.189641e-3
GO:0042732 D-xylose metabolic process 3.191912e-3
GO:0002522 leukocyte migration involved in immune response 3.191912e-3
GO:0044070 regulation of anion transport 3.220437e-3
GO:0060160 negative regulation of dopamine receptor signaling pathway 3.244398e-3
GO:0006335 DNA replication-dependent nucleosome assembly 3.244398e-3
GO:0002003 angiotensin maturation 3.244398e-3
GO:0090342 regulation of cell aging 3.271390e-3
GO:0045347 negative regulation of MHC class II biosynthetic process 3.333643e-3
GO:0022027 interkinetic nuclear migration 3.405414e-3
GO:0070979 protein K11-linked ubiquitination 3.429502e-3
GO:0043128 positive regulation of 1-phosphatidylinositol 4-kinase activity 3.486364e-3
GO:0033600 negative regulation of mammary gland epithelial cell proliferation 3.535278e-3
GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter 3.556098e-3
GO:0009303 rRNA transcription 3.572062e-3
GO:0061014 positive regulation of mRNA catabolic process 3.600659e-3
GO:0006491 N-glycan processing 3.611897e-3
GO:0060017 parathyroid gland development 3.673448e-3
GO:0021871 forebrain regionalization 3.723085e-3
GO:0002921 negative regulation of humoral immune response 3.760661e-3
GO:0033604 negative regulation of catecholamine secretion 3.815003e-3
GO:0042703 menstruation 3.864760e-3
GO:0003406 retinal pigment epithelium development 3.864760e-3
GO:0019101 female somatic sex determination 3.864760e-3
GO:0021986 habenula development 3.910767e-3
GO:0045415 negative regulation of interleukin-8 biosynthetic process 3.984739e-3
GO:0009223 pyrimidine deoxyribonucleotide catabolic process 3.984739e-3
GO:0010512 negative regulation of phosphatidylinositol biosynthetic process 3.984739e-3
GO:0010989 negative regulation of low-density lipoprotein particle clearance 4.005633e-3
GO:0072610 interleukin-12 secretion 4.117701e-3
GO:0002408 myeloid dendritic cell chemotaxis 4.117701e-3
GO:0002074 extraocular skeletal muscle development 4.117701e-3
GO:0097151 positive regulation of inhibitory postsynaptic membrane potential 4.230832e-3
GO:0007090 regulation of S phase of mitotic cell cycle 4.235667e-3
GO:2000465 regulation of glycogen (starch) synthase activity 4.235815e-3
GO:0070309 lens fiber cell morphogenesis 4.251944e-3
GO:0051561 elevation of mitochondrial calcium ion concentration 4.326292e-3
GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter 4.329511e-3
GO:0060683 regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling 4.329511e-3
GO:0071340 skeletal muscle nicotinic acetylcholine receptor clustering 4.463491e-3
GO:0071469 cellular response to alkalinity 4.465577e-3
GO:0031860 telomeric 3' overhang formation 4.465577e-3
GO:0071722 detoxification of arsenic-containing substance 4.465577e-3
GO:0019413 acetate biosynthetic process 4.465577e-3
GO:0019542 propionate biosynthetic process 4.465577e-3
GO:0031081 nuclear pore distribution 4.465577e-3
GO:0006356 regulation of transcription from RNA polymerase I promoter 4.561966e-3
GO:0042309 homoiothermy 4.708885e-3
GO:0046333 octopamine metabolic process 4.708885e-3
GO:0051225 spindle assembly 4.742760e-3
GO:0070307 lens fiber cell development 4.766897e-3
GO:0018208 peptidyl-proline modification 4.788682e-3
GO:0010771 negative regulation of cell morphogenesis involved in differentiation 4.998306e-3
GO:2000077 negative regulation of type B pancreatic cell development 5.156547e-3
GO:0044205 'de novo' UMP biosynthetic process 5.156547e-3
GO:0042797 tRNA transcription from RNA polymerase III promoter 5.259068e-3
GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter 5.259068e-3
GO:0034470 ncRNA processing 5.272550e-3
GO:0032471 reduction of endoplasmic reticulum calcium ion concentration 5.396800e-3
GO:0050772 positive regulation of axonogenesis 5.420742e-3
GO:0006538 glutamate catabolic process 5.533302e-3
GO:0030327 prenylated protein catabolic process 5.626692e-3
GO:0060178 regulation of exocyst localization 5.626692e-3
GO:0001928 regulation of exocyst assembly 5.626692e-3
GO:0072301 regulation of metanephric glomerular mesangial cell proliferation 5.667824e-3
GO:0034969 histone arginine methylation 5.683938e-3
GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development 5.688778e-3
GO:0006281 DNA repair 5.811310e-3
GO:0035414 negative regulation of catenin import into nucleus 5.877360e-3
GO:0051935 glutamate uptake involved in synaptic transmission 5.927361e-3
GO:0006013 mannose metabolic process 5.942210e-3
GO:0051725 protein de-ADP-ribosylation 6.097341e-3
GO:0000022 mitotic spindle elongation 6.097341e-3
GO:0006515 misfolded or incompletely synthesized protein catabolic process 6.141211e-3
GO:0006419 alanyl-tRNA aminoacylation 6.294673e-3
GO:0032288 myelin assembly 6.300203e-3
GO:0016233 telomere capping 6.393833e-3
GO:0006447 regulation of translational initiation by iron 6.393833e-3
GO:0071218 cellular response to misfolded protein 6.427750e-3
GO:0042696 menarche 6.443491e-3
GO:0005997 xylulose metabolic process 6.443491e-3
GO:0002693 positive regulation of cellular extravasation 6.463929e-3
GO:0072061 inner medullary collecting duct development 6.549308e-3
GO:0097022 lymphocyte migration into lymph node 6.549308e-3
GO:0072060 outer medullary collecting duct development 6.549308e-3
GO:0016332 establishment or maintenance of polarity of embryonic epithelium 6.549308e-3
GO:0009798 axis specification 6.579837e-3
GO:0010816 calcitonin catabolic process 6.598159e-3
GO:0034959 endothelin maturation 6.598159e-3
GO:0010814 substance P catabolic process 6.598159e-3
GO:0071316 cellular response to nicotine 6.601396e-3
GO:0035419 activation of MAPK activity involved in innate immune response 6.617259e-3
GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly 6.617259e-3
GO:0051882 mitochondrial depolarization 6.635171e-3
GO:0060286 flagellar cell motility 6.635171e-3
GO:0043622 cortical microtubule organization 6.635171e-3
GO:0030103 vasopressin secretion 6.635171e-3
GO:0045065 cytotoxic T cell differentiation 6.638861e-3
GO:0021796 cerebral cortex regionalization 6.638861e-3
GO:0016140 O-glycoside metabolic process 6.647276e-3
GO:0061205 paramesonephric duct development 6.657975e-3
GO:2000466 negative regulation of glycogen (starch) synthase activity 6.657975e-3
GO:0060242 contact inhibition 6.657975e-3
GO:0034198 cellular response to amino acid starvation 6.657975e-3
GO:0030953 astral microtubule organization 6.812665e-3
GO:0000389 nuclear mRNA 3'-splice site recognition 6.812665e-3
GO:0032321 positive regulation of Rho GTPase activity 6.885635e-3
GO:0015816 glycine transport 6.912870e-3
GO:0021892 cerebral cortex GABAergic interneuron differentiation 6.960311e-3
GO:0045994 positive regulation of translational initiation by iron 7.464846e-3
GO:0000076 DNA replication checkpoint 7.464846e-3
GO:0002037 negative regulation of L-glutamate transport 7.464846e-3
GO:0001522 pseudouridine synthesis 7.512571e-3
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 7.519352e-3
GO:0060976 coronary vasculature development 7.555088e-3
GO:0043985 histone H4-R3 methylation 7.686661e-3
GO:0006547 histidine metabolic process 7.731451e-3
GO:0045820 negative regulation of glycolysis 7.829805e-3
GO:0007020 microtubule nucleation 7.871836e-3
GO:0072081 specification of nephron tubule identity 7.909586e-3
GO:0034080 CenH3-containing nucleosome assembly at centromere 7.938407e-3
GO:0009069 serine family amino acid metabolic process 7.949893e-3
GO:0042167 heme catabolic process 7.978662e-3
GO:0051956 negative regulation of amino acid transport 8.040203e-3
GO:0051955 regulation of amino acid transport 8.050575e-3
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 8.463682e-3
GO:0045329 carnitine biosynthetic process 8.575819e-3
GO:0032793 positive regulation of CREB transcription factor activity 8.647368e-3
GO:0048149 behavioral response to ethanol 8.678771e-3
GO:0006189 'de novo' IMP biosynthetic process 8.828636e-3
GO:0051953 negative regulation of amine transport 8.851401e-3
GO:0090031 positive regulation of steroid hormone biosynthetic process 8.983590e-3
GO:0051220 cytoplasmic sequestering of protein 8.983590e-3
GO:0019083 viral transcription 9.011082e-3
GO:0060998 regulation of dendritic spine development 9.030347e-3
GO:0006415 translational termination 9.112340e-3
GO:0021592 fourth ventricle development 9.211556e-3
GO:0010529 negative regulation of transposition 9.211556e-3
GO:0070814 hydrogen sulfide biosynthetic process 9.295574e-3
GO:0071423 malate transmembrane transport 9.349443e-3
GO:0090324 negative regulation of oxidative phosphorylation 9.349443e-3
GO:0006844 acyl carnitine transport 9.349443e-3
GO:0015919 peroxisomal membrane transport 9.349443e-3
GO:0015709 thiosulfate transport 9.349443e-3
GO:0010255 glucose mediated signaling pathway 9.349443e-3
GO:0090072 positive regulation of sodium ion transport via voltage-gated sodium channel activity 9.493141e-3
GO:0060023 soft palate development 9.493141e-3
GO:0051584 regulation of dopamine uptake 9.534751e-3
GO:0030237 female sex determination 9.594499e-3
GO:0043501 skeletal muscle adaptation 9.624512e-3
GO:0044314 protein K27-linked ubiquitination 9.655168e-3
GO:0061099 negative regulation of protein tyrosine kinase activity 9.797394e-3
GO:0007196 inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway 9.920568e-3
GO:0021759 globus pallidus development 9.920568e-3
GO:0060061 Spemann organizer formation 9.920956e-3
GO:0090150 establishment of protein localization in membrane 1.003449e-2
GO:0060923 cardiac muscle cell fate commitment 1.005365e-2
GO:0097039 protein linear polyubiquitination 1.005365e-2
GO:0001768 establishment of T cell polarity 1.008230e-2
GO:0006707 cholesterol catabolic process 1.012709e-2
GO:0001826 inner cell mass cell differentiation 1.016108e-2
GO:0015864 pyrimidine nucleoside transport 1.016108e-2
GO:0031427 response to methotrexate 1.021992e-2
GO:0060028 convergent extension involved in axis elongation 1.021992e-2
GO:0019086 late viral mRNA transcription 1.021992e-2
GO:0018206 peptidyl-methionine modification 1.027777e-2
GO:0007140 male meiosis 1.029476e-2
GO:0032984 macromolecular complex disassembly 1.029683e-2
GO:0006646 phosphatidylethanolamine biosynthetic process 1.032248e-2
GO:0045943 positive regulation of transcription from RNA polymerase I promoter 1.049359e-2
GO:0001510 RNA methylation 1.050991e-2
GO:0006998 nuclear envelope organization 1.055873e-2
GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity 1.059518e-2
GO:0097107 postsynaptic density assembly 1.059518e-2
GO:0045963 negative regulation of dopamine metabolic process 1.059518e-2
GO:0050668 positive regulation of homocysteine metabolic process 1.059518e-2
GO:0007128 meiotic prophase I 1.086151e-2
GO:0051684 maintenance of Golgi location 1.100458e-2
GO:0042664 negative regulation of endodermal cell fate specification 1.100458e-2
GO:0035481 positive regulation of Notch signaling pathway involved in heart induction 1.100458e-2
GO:0060975 cardioblast migration to the midline involved in heart field formation 1.100458e-2
GO:0060921 sinoatrial node cell differentiation 1.100458e-2
GO:0003236 sinus venosus morphogenesis 1.100458e-2
GO:0003210 cardiac atrium formation 1.100458e-2
GO:0010509 polyamine homeostasis 1.100458e-2
GO:0003241 growth involved in heart morphogenesis 1.100458e-2
GO:0006427 histidyl-tRNA aminoacylation 1.100458e-2
GO:0003259 cardioblast anterior-lateral migration 1.100458e-2
GO:0000089 mitotic metaphase 1.114306e-2
GO:0002606 positive regulation of dendritic cell antigen processing and presentation 1.121726e-2
GO:0009262 deoxyribonucleotide metabolic process 1.130651e-2
GO:0006220 pyrimidine nucleotide metabolic process 1.142849e-2
GO:0030007 cellular potassium ion homeostasis 1.154991e-2
GO:0070212 protein poly-ADP-ribosylation 1.154991e-2
GO:0035510 DNA dealkylation 1.165627e-2
GO:0032933 SREBP-mediated signaling pathway 1.191529e-2
GO:0030262 apoptotic nuclear change 1.207047e-2
GO:0051255 spindle midzone assembly 1.227452e-2
GO:0045717 negative regulation of fatty acid biosynthetic process 1.237775e-2
GO:0031017 exocrine pancreas development 1.262487e-2
GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter 1.263313e-2
GO:0042711 maternal behavior 1.263313e-2
GO:0000432 positive regulation of transcription from RNA polymerase II promoter by glucose 1.263313e-2
GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin 1.271129e-2
GO:0001840 neural plate development 1.271129e-2
GO:0090305 nucleic acid phosphodiester bond hydrolysis 1.296131e-2
GO:0042255 ribosome assembly 1.299052e-2
GO:0010890 positive regulation of sequestering of triglyceride 1.300342e-2
GO:0021569 rhombomere 3 development 1.310448e-2
GO:0010985 negative regulation of lipoprotein particle clearance 1.310448e-2
GO:0051292 nuclear pore complex assembly 1.325877e-2
GO:0042335 cuticle development 1.325877e-2
GO:0016486 peptide hormone processing 1.347268e-2
GO:0060377 negative regulation of mast cell differentiation 1.357771e-2
GO:0045403 negative regulation of interleukin-4 biosynthetic process 1.357771e-2
GO:0070512 positive regulation of histone H4-K20 methylation 1.357771e-2
GO:0022004 midbrain-hindbrain boundary maturation during brain development 1.357771e-2
GO:2000620 positive regulation of histone H4-K16 acetylation 1.357771e-2
GO:2000617 positive regulation of histone H3-K9 acetylation 1.357771e-2
GO:2000002 negative regulation of DNA damage checkpoint 1.357771e-2
GO:0003192 mitral valve formation 1.357771e-2
GO:0003106 negative regulation of glomerular filtration by angiotensin 1.357771e-2
GO:0002295 T-helper cell lineage commitment 1.357771e-2
GO:0003195 tricuspid valve formation 1.357771e-2
GO:0014895 smooth muscle hypertrophy 1.357771e-2
GO:0021551 central nervous system morphogenesis 1.357771e-2
GO:0021588 cerebellum formation 1.357771e-2
GO:0033326 cerebrospinal fluid secretion 1.372116e-2
GO:0090129 positive regulation of synapse maturation 1.397129e-2
GO:0071731 response to nitric oxide 1.404116e-2
GO:0001757 somite specification 1.409022e-2
GO:0002380 immunoglobulin secretion involved in immune response 1.417390e-2
GO:0009235 cobalamin metabolic process 1.417390e-2
GO:0050872 white fat cell differentiation 1.423981e-2
GO:0043241 protein complex disassembly 1.430000e-2
GO:0045819 positive regulation of glycogen catabolic process 1.440582e-2
GO:0045606 positive regulation of epidermal cell differentiation 1.473351e-2
GO:0046628 positive regulation of insulin receptor signaling pathway 1.480721e-2
GO:0009972 cytidine deamination 1.482961e-2
GO:0060920 pacemaker cell differentiation 1.486160e-2
GO:0052565 response to defense-related host nitric oxide production 1.486160e-2
GO:0030844 positive regulation of intermediate filament depolymerization 1.486160e-2
GO:0003175 tricuspid valve development 1.486160e-2
GO:0071474 cellular hyperosmotic response 1.502650e-2
GO:0018105 peptidyl-serine phosphorylation 1.506245e-2
GO:0061013 regulation of mRNA catabolic process 1.508254e-2
GO:0006360 transcription from RNA polymerase I promoter 1.512486e-2
GO:0032008 positive regulation of TOR signaling cascade 1.515469e-2
GO:0032922 circadian regulation of gene expression 1.518460e-2
GO:0071470 cellular response to osmotic stress 1.523477e-2
GO:0070857 regulation of bile acid biosynthetic process 1.529988e-2
GO:0003218 cardiac left ventricle formation 1.529988e-2
GO:0070489 T cell aggregation 1.535679e-2
GO:0043461 proton-transporting ATP synthase complex assembly 1.553976e-2
GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus 1.553976e-2
GO:0072144 glomerular mesangial cell development 1.569032e-2
GO:0060370 susceptibility to T cell mediated cytotoxicity 1.569032e-2
GO:0072011 glomerular endothelium development 1.569032e-2
GO:0009637 response to blue light 1.573790e-2
GO:0034260 negative regulation of GTPase activity 1.585866e-2
GO:0021658 rhombomere 3 morphogenesis 1.588456e-2
GO:0051182 coenzyme transport 1.588456e-2
GO:0006546 glycine catabolic process 1.593654e-2
GO:0015862 uridine transport 1.596817e-2
GO:0003184 pulmonary valve morphogenesis 1.596817e-2
GO:0060179 male mating behavior 1.597501e-2
GO:0045199 maintenance of epithelial cell apical/basal polarity 1.597501e-2
GO:0007063 regulation of sister chromatid cohesion 1.601338e-2
GO:0006284 base-excision repair 1.603961e-2
GO:0009394 2'-deoxyribonucleotide metabolic process 1.644682e-2
GO:0009070 serine family amino acid biosynthetic process 1.651787e-2
GO:0000712 resolution of meiotic recombination intermediates 1.657640e-2
GO:0072553 terminal button organization 1.696495e-2
GO:0034231 islet amyloid polypeptide processing 1.696495e-2
GO:0000088 mitotic prophase 1.696495e-2
GO:0034230 enkephalin processing 1.696495e-2


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0050668 positive regulation of homocysteine metabolic process 9.993106e-7
GO:0045963 negative regulation of dopamine metabolic process 9.993106e-7
GO:0055015 ventricular cardiac muscle cell development 2.535470e-6
GO:0071294 cellular response to zinc ion 3.386559e-6
GO:0043973 histone H3-K4 acetylation 4.228854e-6
GO:0046985 positive regulation of hemoglobin biosynthetic process 4.228854e-6
GO:0035269 protein O-linked mannosylation 4.228854e-6
GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery 4.228854e-6
GO:0006829 zinc ion transport 4.240007e-6
GO:2000020 positive regulation of male gonad development 6.673759e-6
GO:0018192 enzyme active site formation via L-cysteine persulfide 1.584391e-5
GO:0035307 positive regulation of protein dephosphorylation 2.235522e-5
GO:0000183 chromatin silencing at rDNA 2.334561e-5
GO:0090161 Golgi ribbon formation 2.415763e-5
GO:0030035 microspike assembly 2.761058e-5
GO:0061034 olfactory bulb mitral cell layer development 2.842038e-5
GO:0035306 positive regulation of dephosphorylation 3.318695e-5
GO:0070316 regulation of G0 to G1 transition 3.399904e-5
GO:0046847 filopodium assembly 3.575974e-5
GO:2000195 negative regulation of female gonad development 5.229123e-5
GO:0021526 medial motor column neuron differentiation 5.347379e-5
GO:0071422 succinate transmembrane transport 5.347379e-5
GO:0046580 negative regulation of Ras protein signal transduction 5.422592e-5
GO:2000018 regulation of male gonad development 5.572383e-5
GO:0016925 protein sumoylation 5.623617e-5
GO:0006383 transcription from RNA polymerase III promoter 5.706498e-5
GO:0021696 cerebellar cortex morphogenesis 7.341940e-5
GO:0048672 positive regulation of collateral sprouting 8.248710e-5
GO:0021819 layer formation in cerebral cortex 8.251215e-5
GO:0021527 spinal cord association neuron differentiation 8.383226e-5
GO:0048665 neuron fate specification 9.139195e-5
GO:0070179 D-serine biosynthetic process 9.998660e-5
GO:0035674 tricarboxylic acid transmembrane transport 9.998660e-5
GO:0014028 notochord formation 9.998660e-5
GO:0046984 regulation of hemoglobin biosynthetic process 1.001283e-4
GO:0046416 D-amino acid metabolic process 1.191805e-4
GO:0051586 positive regulation of dopamine uptake 1.447431e-4
GO:0051058 negative regulation of small GTPase mediated signal transduction 1.565917e-4
GO:0006297 nucleotide-excision repair, DNA gap filling 1.687811e-4
GO:0021695 cerebellar cortex development 1.691995e-4
GO:0003221 right ventricular cardiac muscle tissue morphogenesis 2.010220e-4
GO:0006011 UDP-glucose metabolic process 2.016877e-4
GO:0035520 monoubiquitinated protein deubiquitination 2.016877e-4
GO:0021511 spinal cord patterning 2.330415e-4
GO:0018205 peptidyl-lysine modification 2.407067e-4
GO:0021513 spinal cord dorsal/ventral patterning 2.430810e-4
GO:0035024 negative regulation of Rho protein signal transduction 2.437699e-4
GO:0015876 acetyl-CoA transport 2.511731e-4
GO:0006342 chromatin silencing 2.529235e-4
GO:0035444 nickel ion transmembrane transport 2.607722e-4
GO:0070278 extracellular matrix constituent secretion 2.636115e-4
GO:0010260 organ senescence 2.636115e-4
GO:0002098 tRNA wobble uridine modification 2.749667e-4
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2.970552e-4
GO:0060452 positive regulation of cardiac muscle contraction 2.970552e-4
GO:0051176 positive regulation of sulfur metabolic process 3.216518e-4
GO:0034227 tRNA thio-modification 3.817561e-4
GO:0018076 N-terminal peptidyl-lysine acetylation 3.817561e-4
GO:0032312 regulation of ARF GTPase activity 3.909787e-4
GO:2000194 regulation of female gonad development 3.930340e-4
GO:0021871 forebrain regionalization 4.107554e-4
GO:0055014 atrial cardiac muscle cell development 4.396171e-4
GO:0045647 negative regulation of erythrocyte differentiation 4.700188e-4
GO:0090083 regulation of inclusion body assembly 4.821897e-4
GO:0035855 megakaryocyte development 4.821897e-4
GO:0006474 N-terminal protein amino acid acetylation 4.924490e-4
GO:0070318 positive regulation of G0 to G1 transition 5.037032e-4
GO:0021514 ventral spinal cord interneuron differentiation 5.270274e-4
GO:0070831 basement membrane assembly 5.780599e-4
GO:0019255 glucose 1-phosphate metabolic process 5.906008e-4
GO:0019101 female somatic sex determination 6.309555e-4
GO:0072355 histone H3-T3 phosphorylation 6.309555e-4
GO:0042703 menstruation 6.309555e-4
GO:0006121 mitochondrial electron transport, succinate to ubiquinone 6.309555e-4
GO:0006258 UDP-glucose catabolic process 6.309555e-4
GO:0018293 protein-FAD linkage 6.309555e-4
GO:0060579 ventral spinal cord interneuron fate commitment 6.476981e-4
GO:0001825 blastocyst formation 6.648465e-4
GO:0021797 forebrain anterior/posterior pattern specification 6.656963e-4
GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 7.018326e-4
GO:0043314 negative regulation of neutrophil degranulation 7.808992e-4
GO:0035802 adrenal cortex formation 7.948504e-4
GO:0002074 extraocular skeletal muscle development 7.948504e-4
GO:0042273 ribosomal large subunit biogenesis 8.019034e-4
GO:0046102 inosine metabolic process 8.894790e-4
GO:0016573 histone acetylation 9.422816e-4
GO:0007140 male meiosis 9.594259e-4
GO:0010735 positive regulation of transcription via serum response element binding 9.614174e-4
GO:0060896 neural plate pattern specification 9.799109e-4
GO:0035507 regulation of myosin-light-chain-phosphatase activity 1.018121e-3
GO:0030851 granulocyte differentiation 1.035966e-3
GO:0031507 heterochromatin formation 1.060482e-3
GO:0019359 nicotinamide nucleotide biosynthetic process 1.109625e-3
GO:0030431 sleep 1.184940e-3
GO:0015670 carbon dioxide transport 1.195536e-3
GO:0033239 negative regulation of cellular amine metabolic process 1.242820e-3
GO:0001829 trophectodermal cell differentiation 1.258818e-3
GO:0014909 smooth muscle cell migration 1.281764e-3
GO:0042428 serotonin metabolic process 1.466389e-3
GO:0071577 zinc ion transmembrane transport 1.481818e-3
GO:0032119 sequestering of zinc ion 1.540840e-3
GO:0006409 tRNA export from nucleus 1.584961e-3
GO:0071169 establishment of protein localization to chromatin 1.584961e-3
GO:0031468 nuclear envelope reassembly 1.584961e-3
GO:0040040 thermosensory behavior 1.611851e-3
GO:0002730 regulation of dendritic cell cytokine production 1.611851e-3
GO:0032319 regulation of Rho GTPase activity 1.613900e-3
GO:0019673 GDP-mannose metabolic process 1.645559e-3
GO:0051443 positive regulation of ubiquitin-protein ligase activity 1.655260e-3
GO:0030219 megakaryocyte differentiation 1.659229e-3
GO:0021521 ventral spinal cord interneuron specification 1.694069e-3
GO:0009435 NAD biosynthetic process 1.731742e-3
GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity 1.835854e-3
GO:0097107 postsynaptic density assembly 1.835854e-3
GO:0031914 negative regulation of synaptic plasticity 1.835854e-3
GO:0070845 polyubiquitinated misfolded protein transport 1.835854e-3
GO:0048384 retinoic acid receptor signaling pathway 1.847341e-3
GO:0010950 positive regulation of endopeptidase activity 1.866293e-3
GO:0071715 icosanoid transport 1.874354e-3
GO:0060033 anatomical structure regression 1.910299e-3
GO:0045908 negative regulation of vasodilation 1.911964e-3
GO:0030903 notochord development 1.936181e-3
GO:0060124 positive regulation of growth hormone secretion 1.968233e-3
GO:0030828 positive regulation of cGMP biosynthetic process 1.985239e-3
GO:0021697 cerebellar cortex formation 2.007510e-3
GO:0050685 positive regulation of mRNA processing 2.024195e-3
GO:0046498 S-adenosylhomocysteine metabolic process 2.072863e-3
GO:0021515 cell differentiation in spinal cord 2.124936e-3
GO:0043300 regulation of leukocyte degranulation 2.225941e-3
GO:0030902 hindbrain development 2.302367e-3
GO:0033158 regulation of protein import into nucleus, translocation 2.302706e-3
GO:0032774 RNA biosynthetic process 2.358491e-3
GO:0006601 creatine biosynthetic process 2.396398e-3
GO:0010544 negative regulation of platelet activation 2.499162e-3
GO:0046717 acid secretion 2.525320e-3
GO:0030046 parallel actin filament bundle assembly 2.668934e-3
GO:0042694 muscle cell fate specification 2.668934e-3
GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway 2.694291e-3
GO:0021587 cerebellum morphogenesis 2.766016e-3
GO:0032784 regulation of transcription elongation, DNA-dependent 2.772369e-3
GO:0048025 negative regulation of nuclear mRNA splicing, via spliceosome 2.898044e-3
GO:0045112 integrin biosynthetic process 2.910084e-3
GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation 2.910084e-3
GO:0042866 pyruvate biosynthetic process 2.910084e-3
GO:0015747 urate transport 2.916217e-3
GO:0008612 peptidyl-lysine modification to hypusine 2.916217e-3
GO:0007143 female meiosis 2.977467e-3
GO:0060319 primitive erythrocyte differentiation 3.085430e-3
GO:0042053 regulation of dopamine metabolic process 3.086493e-3
GO:0030031 cell projection assembly 3.155171e-3
GO:0006351 transcription, DNA-dependent 3.175968e-3
GO:0018394 peptidyl-lysine acetylation 3.177114e-3
GO:2000772 regulation of cellular senescence 3.310945e-3
GO:0006473 protein acetylation 3.339276e-3
GO:0030970 retrograde protein transport, ER to cytosol 3.364034e-3
GO:0018393 internal peptidyl-lysine acetylation 3.401422e-3
GO:0021549 cerebellum development 3.481749e-3
GO:0045454 cell redox homeostasis 3.563828e-3
GO:0071340 skeletal muscle nicotinic acetylcholine receptor clustering 3.669215e-3
GO:0035611 protein branching point deglutamylation 3.669215e-3
GO:0048663 neuron fate commitment 3.727215e-3
GO:0018364 peptidyl-glutamine methylation 3.737723e-3
GO:0046103 inosine biosynthetic process 3.737723e-3
GO:0006154 adenosine catabolic process 3.737723e-3
GO:0048227 plasma membrane to endosome transport 3.981374e-3
GO:0021528 commissural neuron differentiation in spinal cord 3.981374e-3
GO:0021516 dorsal spinal cord development 4.306356e-3
GO:0045162 clustering of voltage-gated sodium channels 4.346827e-3
GO:0019348 dolichol metabolic process 4.346827e-3
GO:0001840 neural plate development 4.454716e-3
GO:0042136 neurotransmitter biosynthetic process 4.464516e-3
GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation 4.464516e-3
GO:0034453 microtubule anchoring 4.477718e-3
GO:0090084 negative regulation of inclusion body assembly 4.558234e-3
GO:2000383 regulation of ectoderm development 4.558234e-3
GO:0043543 protein acylation 4.563644e-3
GO:0006290 pyrimidine dimer repair 4.825750e-3
GO:0007352 zygotic specification of dorsal/ventral axis 4.916645e-3
GO:0032321 positive regulation of Rho GTPase activity 4.946513e-3
GO:0042420 dopamine catabolic process 4.961818e-3
GO:0048840 otolith development 4.977790e-3
GO:0042069 regulation of catecholamine metabolic process 5.280366e-3
GO:0051567 histone H3-K9 methylation 5.307952e-3
GO:0034059 response to anoxia 5.480393e-3
GO:0048670 regulation of collateral sprouting 5.499090e-3
GO:0016068 type I hypersensitivity 5.706935e-3
GO:0035621 ER to Golgi ceramide transport 5.706935e-3
GO:0009798 axis specification 5.711670e-3
GO:0072224 metanephric glomerulus development 5.984818e-3
GO:0021575 hindbrain morphogenesis 6.034701e-3
GO:0050891 multicellular organismal water homeostasis 6.081212e-3
GO:0072302 negative regulation of metanephric glomerular mesangial cell proliferation 6.150168e-3
GO:2001076 positive regulation of metanephric ureteric bud development 6.150168e-3
GO:0018065 protein-cofactor linkage 6.150168e-3
GO:0007356 thorax and anterior abdomen determination 6.150168e-3
GO:0090218 positive regulation of lipid kinase activity 6.563241e-3
GO:0035928 rRNA import into mitochondrion 6.691318e-3
GO:0006668 sphinganine-1-phosphate metabolic process 6.691318e-3
GO:0002481 antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent 6.691318e-3
GO:0048570 notochord morphogenesis 6.862669e-3
GO:0035625 epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway 7.115672e-3
GO:0009452 RNA capping 7.223038e-3
GO:0032571 response to vitamin K 7.436684e-3
GO:2001037 positive regulation of tongue muscle cell differentiation 7.436684e-3
GO:2000384 negative regulation of ectoderm development 7.436684e-3
GO:0018993 somatic sex determination 7.491491e-3
GO:0008611 ether lipid biosynthetic process 7.491491e-3
GO:0043457 regulation of cellular respiration 7.787230e-3
GO:0072166 posterior mesonephric tubule development 7.821569e-3
GO:0060978 angiogenesis involved in coronary vascular morphogenesis 7.821569e-3
GO:0051238 sequestering of metal ion 7.873304e-3
GO:0023021 termination of signal transduction 7.873304e-3
GO:0007216 metabotropic glutamate receptor signaling pathway 7.927011e-3
GO:0021794 thalamus development 8.171295e-3
GO:0042998 positive regulation of Golgi to plasma membrane protein transport 8.263002e-3
GO:0060928 atrioventricular node cell development 8.263002e-3
GO:0060929 atrioventricular node cell fate commitment 8.263002e-3
GO:0031119 tRNA pseudouridine synthesis 8.263002e-3
GO:0032782 bile acid secretion 8.263002e-3
GO:0017196 N-terminal peptidyl-methionine acetylation 8.263002e-3
GO:0003342 proepicardium development 8.263002e-3
GO:0003168 cardiac Purkinje fiber cell differentiation 8.263002e-3
GO:0003096 renal sodium ion transport 8.263002e-3
GO:0015761 mannose transport 8.263002e-3
GO:0006837 serotonin transport 8.370684e-3
GO:0050482 arachidonic acid secretion 8.405538e-3
GO:0070309 lens fiber cell morphogenesis 8.743304e-3
GO:0015746 citrate transport 8.967865e-3
GO:0007614 short-term memory 9.217850e-3
GO:0022037 metencephalon development 9.644294e-3
GO:0072015 glomerular visceral epithelial cell development 9.857285e-3
GO:0032515 negative regulation of phosphoprotein phosphatase activity 9.857285e-3
GO:0015696 ammonium transport 9.950588e-3
GO:0070430 positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 1.000096e-2
GO:0051684 maintenance of Golgi location 1.000096e-2
GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 1.000096e-2
GO:2000119 negative regulation of sodium-dependent phosphate transport 1.000096e-2
GO:0071624 positive regulation of granulocyte chemotaxis 1.000096e-2
GO:0050983 deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase 1.000096e-2
GO:0031619 homologous chromosome orientation involved in meiotic metaphase I plate congression 1.000096e-2
GO:0019676 ammonia assimilation cycle 1.000096e-2
GO:0002368 B cell cytokine production 1.000096e-2
GO:0032707 negative regulation of interleukin-23 production 1.000096e-2
GO:0042450 arginine biosynthetic process via ornithine 1.000096e-2
GO:0045362 positive regulation of interleukin-1 biosynthetic process 1.000096e-2
GO:0048291 isotype switching to IgG isotypes 1.000096e-2
GO:0007144 female meiosis I 1.014357e-2
GO:0001678 cellular glucose homeostasis 1.027945e-2
GO:0034447 very-low-density lipoprotein particle clearance 1.038359e-2
GO:0090224 regulation of spindle organization 1.052144e-2
GO:0006403 RNA localization 1.069355e-2
GO:0048339 paraxial mesoderm development 1.082552e-2
GO:0048671 negative regulation of collateral sprouting 1.084827e-2
GO:0060123 regulation of growth hormone secretion 1.102284e-2
GO:0021702 cerebellar Purkinje cell differentiation 1.124839e-2
GO:0071157 negative regulation of cell cycle arrest 1.129609e-2
GO:0043302 positive regulation of leukocyte degranulation 1.140192e-2
GO:0032012 regulation of ARF protein signal transduction 1.141599e-2
GO:0042424 catecholamine catabolic process 1.147507e-2
GO:0021938 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation 1.147507e-2
GO:0001831 trophectodermal cellular morphogenesis 1.147507e-2
GO:0071394 cellular response to testosterone stimulus 1.172243e-2
GO:0060947 cardiac vascular smooth muscle cell differentiation 1.174361e-2
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 1.180766e-2
GO:0070368 positive regulation of hepatocyte differentiation 1.189867e-2
GO:0006475 internal protein amino acid acetylation 1.191020e-2
GO:0033160 positive regulation of protein import into nucleus, translocation 1.195776e-2
GO:0003091 renal water homeostasis 1.214079e-2
GO:0021997 neural plate axis specification 1.219898e-2
GO:0032855 positive regulation of Rac GTPase activity 1.253762e-2
GO:0060948 cardiac vascular smooth muscle cell development 1.263527e-2
GO:0031662 positive regulation of cyclin-dependent protein kinase activity involved in G2/M 1.263527e-2
GO:0045814 negative regulation of gene expression, epigenetic 1.265970e-2
GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway 1.273236e-2
GO:0060729 intestinal epithelial structure maintenance 1.275614e-2
GO:0007418 ventral midline development 1.275614e-2
GO:0021681 cerebellar granular layer development 1.315284e-2
GO:0055012 ventricular cardiac muscle cell differentiation 1.318447e-2
GO:0051351 positive regulation of ligase activity 1.367024e-2
GO:0048340 paraxial mesoderm morphogenesis 1.409282e-2
GO:0043304 regulation of mast cell degranulation 1.434531e-2
GO:0048368 lateral mesoderm development 1.438582e-2
GO:0032792 negative regulation of CREB transcription factor activity 1.446826e-2
GO:0001778 plasma membrane repair 1.446826e-2
GO:0006405 RNA export from nucleus 1.468534e-2
GO:0060163 subpallium neuron fate commitment 1.474487e-2
GO:0060217 hemangioblast cell differentiation 1.474487e-2
GO:0090035 positive regulation of cellular chaperone-mediated protein complex assembly 1.474487e-2
GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity 1.474487e-2
GO:2000016 negative regulation of determination of dorsal identity 1.474487e-2
GO:0006408 snRNA export from nucleus 1.474487e-2
GO:0000073 spindle pole body separation 1.474487e-2
GO:0045799 positive regulation of chromatin assembly or disassembly 1.474487e-2
GO:0022417 protein maturation by protein folding 1.474487e-2
GO:0045299 otolith mineralization 1.474487e-2
GO:0010447 response to acidity 1.494362e-2
GO:0060911 cardiac cell fate commitment 1.517469e-2
GO:0031365 N-terminal protein amino acid modification 1.533315e-2
GO:0010669 epithelial structure maintenance 1.576470e-2
GO:0006884 cell volume homeostasis 1.581944e-2
GO:0033006 regulation of mast cell activation involved in immune response 1.628879e-2
GO:0060215 primitive hemopoiesis 1.634056e-2
GO:0007616 long-term memory 1.664769e-2
GO:0032836 glomerular basement membrane development 1.665246e-2
GO:0072239 metanephric glomerulus vasculature development 1.665741e-2
GO:0051313 attachment of spindle microtubules to chromosome 1.665741e-2
GO:0060923 cardiac muscle cell fate commitment 1.669301e-2
GO:0060971 embryonic heart tube left/right pattern formation 1.687591e-2
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 1.687591e-2
GO:0016191 synaptic vesicle uncoating 1.687591e-2
GO:0032805 positive regulation of low-density lipoprotein particle receptor catabolic process 1.687591e-2
GO:0043306 positive regulation of mast cell degranulation 1.690943e-2
GO:0048251 elastic fiber assembly 1.717247e-2
GO:0060177 regulation of angiotensin metabolic process 1.722207e-2
GO:0045750 positive regulation of S phase of mitotic cell cycle 1.741367e-2
GO:0043313 regulation of neutrophil degranulation 1.741367e-2
GO:0015879 carnitine transport 1.778341e-2
GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation 1.818008e-2
GO:2000774 positive regulation of cellular senescence 1.819913e-2
GO:0090402 oncogene-induced senescence 1.819913e-2
GO:0035986 senescence-associated heterochromatin focus formation 1.819913e-2
GO:0035810 positive regulation of urine volume 1.819913e-2
GO:0001880 Mullerian duct regression 1.832961e-2
GO:0032853 positive regulation of Ran GTPase activity 1.835985e-2
GO:0030322 stabilization of membrane potential 1.835985e-2
GO:0015966 diadenosine tetraphosphate biosynthetic process 1.835985e-2
GO:0072104 glomerular capillary formation 1.836274e-2
GO:0015692 lead ion transport 1.841222e-2
GO:0070627 ferrous iron import 1.841222e-2
GO:0015676 vanadium ion transport 1.841222e-2
GO:0010312 detoxification of zinc ion 1.841222e-2
GO:0045880 positive regulation of smoothened signaling pathway 1.844742e-2
GO:0051865 protein autoubiquitination 1.874797e-2
GO:0003002 regionalization 1.882298e-2
GO:0002886 regulation of myeloid leukocyte mediated immunity 1.924898e-2
GO:0050772 positive regulation of axonogenesis 1.929561e-2
GO:0006824 cobalt ion transport 1.944308e-2
GO:0006669 sphinganine-1-phosphate biosynthetic process 1.946993e-2
GO:0045943 positive regulation of transcription from RNA polymerase I promoter 1.985779e-2
GO:0060024 rhythmic synaptic transmission 1.985779e-2
GO:0030221 basophil differentiation 2.014796e-2
GO:0021508 floor plate formation 2.014796e-2
GO:0006189 'de novo' IMP biosynthetic process 2.014796e-2
GO:0015824 proline transport 2.019782e-2
GO:0014047 glutamate secretion 2.019782e-2
GO:0016572 histone phosphorylation 2.024949e-2
GO:0060561 apoptosis involved in morphogenesis 2.039129e-2
GO:0032926 negative regulation of activin receptor signaling pathway 2.045019e-2
GO:0042747 circadian sleep/wake cycle, REM sleep 2.052689e-2
GO:0019388 galactose catabolic process 2.052689e-2
GO:0031442 positive regulation of mRNA 3'-end processing 2.058339e-2
GO:0045905 positive regulation of translational termination 2.063203e-2
GO:0045901 positive regulation of translational elongation 2.063203e-2
GO:0051639 actin filament network formation 2.063203e-2
GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity 2.063203e-2
GO:0030505 inorganic diphosphate transport 2.063203e-2
GO:0006452 translational frameshifting 2.063203e-2
GO:0034653 retinoic acid catabolic process 2.063203e-2
GO:2000381 negative regulation of mesoderm development 2.067116e-2
GO:0065001 specification of axis polarity 2.067116e-2
GO:0010991 negative regulation of SMAD protein complex assembly 2.067116e-2
GO:0030837 negative regulation of actin filament polymerization 2.072141e-2
GO:0035886 vascular smooth muscle cell differentiation 2.157125e-2
GO:0045657 positive regulation of monocyte differentiation 2.163074e-2
GO:0030968 endoplasmic reticulum unfolded protein response 2.167856e-2
GO:0070293 renal absorption 2.221275e-2
GO:0072125 negative regulation of glomerular mesangial cell proliferation 2.255754e-2
GO:0033120 positive regulation of RNA splicing 2.259051e-2
GO:0021510 spinal cord development 2.266035e-2
GO:0014056 regulation of acetylcholine secretion 2.350872e-2
GO:0061104 adrenal chromaffin cell differentiation 2.434126e-2
GO:0061103 carotid body glomus cell differentiation 2.434126e-2
GO:0071247 cellular response to chromate 2.434126e-2
GO:0072500 negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor 2.434126e-2
GO:0061102 stomach neuroendocrine cell differentiation 2.434126e-2
GO:0071259 cellular response to magnetism 2.434126e-2
GO:0003359 noradrenergic neuron fate commitment 2.434126e-2
GO:0007400 neuroblast fate determination 2.434126e-2
GO:0000059 protein import into nucleus, docking 2.434126e-2
GO:0034259 negative regulation of Rho GTPase activity 2.434126e-2
GO:0048697 positive regulation of collateral sprouting in absence of injury 2.434126e-2
GO:0060165 regulation of timing of subpallium neuron differentiation 2.434126e-2
GO:0061100 lung neuroendocrine cell differentiation 2.434126e-2
GO:0032849 positive regulation of cellular pH reduction 2.448145e-2
GO:0085029 extracellular matrix assembly 2.467963e-2
GO:0021683 cerebellar granular layer morphogenesis 2.508679e-2
GO:0080164 regulation of nitric oxide metabolic process 2.512144e-2
GO:0070317 negative regulation of G0 to G1 transition 2.512144e-2
GO:0035502 metanephric ureteric bud development 2.512144e-2
GO:0060035 notochord cell development 2.512144e-2
GO:0006882 cellular zinc ion homeostasis 2.537424e-2
GO:2000210 positive regulation of anoikis 2.547187e-2
GO:0072112 glomerular visceral epithelial cell differentiation 2.627671e-2
GO:0060359 response to ammonium ion 2.647480e-2
GO:0021612 facial nerve structural organization 2.748343e-2
GO:0048026 positive regulation of nuclear mRNA splicing, via spliceosome 2.813234e-2
GO:0071333 cellular response to glucose stimulus 2.814998e-2
GO:0033566 gamma-tubulin complex localization 2.840995e-2
GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase 2.840995e-2
GO:0034048 negative regulation of protein phosphatase type 2A activity 2.840995e-2
GO:0006235 dTTP biosynthetic process 2.840995e-2
GO:0010966 regulation of phosphate transport 2.840995e-2
GO:0018230 peptidyl-L-cysteine S-palmitoylation 2.840995e-2
GO:0032416 negative regulation of sodium:hydrogen antiporter activity 2.840995e-2
GO:0070574 cadmium ion transmembrane transport 2.848880e-2
GO:0008608 attachment of spindle microtubules to kinetochore 2.848880e-2
GO:0035313 wound healing, spreading of epidermal cells 2.877688e-2
GO:0033083 regulation of immature T cell proliferation 2.908229e-2
GO:0021546 rhombomere development 2.908229e-2
GO:0009649 entrainment of circadian clock 2.912371e-2
GO:0032481 positive regulation of type I interferon production 2.926533e-2
GO:0009168 purine ribonucleoside monophosphate biosynthetic process 2.943509e-2
GO:0000072 M phase specific microtubule process 2.947926e-2
GO:0055075 potassium ion homeostasis 2.948085e-2
GO:0007097 nuclear migration 2.989652e-2
GO:0021517 ventral spinal cord development 3.005197e-2
GO:0051303 establishment of chromosome localization 3.034442e-2
GO:0031584 activation of phospholipase D activity 3.043962e-2
GO:0042363 fat-soluble vitamin catabolic process 3.043962e-2
GO:0034587 piRNA metabolic process 3.060216e-2
GO:0001820 serotonin secretion 3.061349e-2
GO:0043551 regulation of phosphatidylinositol 3-kinase activity 3.064946e-2
GO:0043276 anoikis 3.088729e-2
GO:0021569 rhombomere 3 development 3.088729e-2
GO:0001955 blood vessel maturation 3.088729e-2
GO:0042360 vitamin E metabolic process 3.106497e-2
GO:0031129 inductive cell-cell signaling 3.106497e-2
GO:0007264 small GTPase mediated signal transduction 3.107628e-2
GO:0006449 regulation of translational termination 3.135010e-2
GO:0005981 regulation of glycogen catabolic process 3.146950e-2
GO:0055069 zinc ion homeostasis 3.189796e-2
GO:0006415 translational termination 3.235235e-2
GO:0035912 dorsal aorta morphogenesis 3.269200e-2
GO:0034421 post-translational protein acetylation 3.269200e-2
GO:0046952 ketone body catabolic process 3.269200e-2
GO:0046940 nucleoside monophosphate phosphorylation 3.269200e-2
GO:0033572 transferrin transport 3.269200e-2
GO:0008216 spermidine metabolic process 3.269200e-2
GO:0021979 hypothalamus cell differentiation 3.269200e-2
GO:0030038 contractile actin filament bundle assembly 3.269200e-2
GO:0090234 regulation of kinetochore assembly 3.291018e-2
GO:0090169 regulation of spindle assembly 3.291018e-2
GO:2000124 regulation of endocannabinoid signaling pathway 3.291018e-2
GO:0022616 DNA strand elongation 3.291018e-2
GO:0003056 regulation of vascular smooth muscle contraction 3.291018e-2
GO:0051292 nuclear pore complex assembly 3.348141e-2
GO:0072262 metanephric glomerular mesangial cell proliferation involved in metanephros development 3.348141e-2
GO:0006438 valyl-tRNA aminoacylation 3.348141e-2
GO:0032933 SREBP-mediated signaling pathway 3.355352e-2
GO:0021523 somatic motor neuron differentiation 3.355352e-2
GO:0015891 siderophore transport 3.357140e-2
GO:0000415 negative regulation of histone H3-K36 methylation 3.357140e-2
GO:0001830 trophectodermal cell fate commitment 3.357140e-2
GO:0043923 positive regulation by host of viral transcription 3.359909e-2
GO:0007090 regulation of S phase of mitotic cell cycle 3.363239e-2
GO:0060032 notochord regression 3.383944e-2
GO:0032613 interleukin-10 production 3.383944e-2
GO:0045906 negative regulation of vasoconstriction 3.387624e-2
GO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway 3.387624e-2
GO:0015937 coenzyme A biosynthetic process 3.390002e-2
GO:0034498 early endosome to Golgi transport 3.390512e-2
GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway 3.390512e-2
GO:0021530 spinal cord oligodendrocyte cell fate specification 3.390512e-2
GO:0009953 dorsal/ventral pattern formation 3.397682e-2
GO:0072488 ammonium transmembrane transport 3.545847e-2
GO:0009264 deoxyribonucleotide catabolic process 3.545847e-2
GO:0042733 embryonic digit morphogenesis 3.627837e-2
GO:0043624 cellular protein complex disassembly 3.638947e-2
GO:0010665 regulation of cardiac muscle cell apoptosis 3.692693e-2
GO:0070584 mitochondrion morphogenesis 3.739984e-2
GO:0006364 rRNA processing 3.747501e-2
GO:0021707 cerebellar granule cell differentiation 3.757792e-2
GO:0035176 social behavior 3.759008e-2
GO:0001824 blastocyst development 3.795818e-2
GO:0043967 histone H4 acetylation 3.869058e-2
GO:2000015 regulation of determination of dorsal identity 3.879108e-2
GO:0072333 signal transduction by p53 class mediator resulting in induction of anoikis 3.879108e-2
GO:0010667 negative regulation of cardiac muscle cell apoptosis 3.919402e-2
GO:0009113 purine base biosynthetic process 3.932515e-2
GO:0007182 common-partner SMAD protein phosphorylation 3.957427e-2
GO:0042942 D-serine transport 4.009888e-2
GO:0034725 DNA replication-dependent nucleosome disassembly 4.009888e-2
GO:0051160 L-xylitol catabolic process 4.009888e-2
GO:0071352 cellular response to interleukin-2 4.009888e-2
GO:0046604 positive regulation of mitotic centrosome separation 4.009888e-2
GO:0046370 fructose biosynthetic process 4.009888e-2
GO:0034276 kynurenic acid biosynthetic process 4.009888e-2
GO:0000027 ribosomal large subunit assembly 4.009888e-2
GO:0002534 cytokine production involved in inflammatory response 4.009888e-2
GO:0002357 defense response to tumor cell 4.009888e-2
GO:0021941 negative regulation of cerebellar granule cell precursor proliferation 4.009888e-2
GO:0006062 sorbitol catabolic process 4.009888e-2
GO:0060026 convergent extension 4.046004e-2
GO:0031333 negative regulation of protein complex assembly 4.122744e-2
GO:0043586 tongue development 4.134537e-2
GO:0055089 fatty acid homeostasis 4.135120e-2
GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 4.168434e-2
GO:0006999 nuclear pore organization 4.168434e-2
GO:0002524 hypersensitivity 4.168434e-2
GO:0045862 positive regulation of proteolysis 4.176391e-2