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Novel motif:118

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name:motif118_AATCCGGCT

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0031167 rRNA methylation 1.880964e-8
GO:0009744 response to sucrose stimulus 8.964676e-8
GO:0010871 negative regulation of receptor biosynthetic process 2.944896e-7
GO:0000154 rRNA modification 3.165911e-7
GO:0043457 regulation of cellular respiration 4.277974e-7
GO:0006391 transcription initiation from mitochondrial promoter 4.523933e-7
GO:0010999 regulation of eIF2 alpha phosphorylation by heme 5.647065e-7
GO:0009589 detection of UV 5.647065e-7
GO:0015742 alpha-ketoglutarate transport 6.789946e-7
GO:0070489 T cell aggregation 8.424625e-7
GO:0006290 pyrimidine dimer repair 1.488336e-6
GO:0042137 sequestering of neurotransmitter 1.776669e-6
GO:0051152 positive regulation of smooth muscle cell differentiation 2.922363e-6
GO:0046732 active induction of host immune response by virus 3.689583e-6
GO:0002456 T cell mediated immunity 3.956429e-6
GO:0051383 kinetochore organization 4.309302e-6
GO:0051382 kinetochore assembly 5.495637e-6
GO:0007168 receptor guanylyl cyclase signaling pathway 5.827152e-6
GO:0006261 DNA-dependent DNA replication 6.694707e-6
GO:0055099 response to high density lipoprotein particle stimulus 7.271615e-6
GO:0000088 mitotic prophase 9.953653e-6
GO:0060364 frontal suture morphogenesis 1.246552e-5
GO:0050765 negative regulation of phagocytosis 1.868442e-5
GO:0021557 oculomotor nerve development 2.162131e-5
GO:0042481 regulation of odontogenesis 2.195531e-5
GO:0043163 cell envelope organization 2.272029e-5
GO:0031627 telomeric loop formation 2.324623e-5
GO:0071593 lymphocyte aggregation 2.493557e-5
GO:0006540 glutamate decarboxylation to succinate 3.280186e-5
GO:0006817 phosphate ion transport 3.325799e-5
GO:0071109 superior temporal gyrus development 3.833555e-5
GO:0032801 receptor catabolic process 3.953051e-5
GO:0050783 cocaine metabolic process 4.315896e-5
GO:0045773 positive regulation of axon extension 4.392699e-5
GO:0051534 negative regulation of NFAT protein import into nucleus 4.461664e-5
GO:0007031 peroxisome organization 4.861141e-5
GO:0021783 preganglionic parasympathetic nervous system development 4.898915e-5
GO:0021602 cranial nerve morphogenesis 4.989855e-5
GO:0071042 nuclear polyadenylation-dependent mRNA catabolic process 5.498782e-5
GO:2000627 positive regulation of miRNA catabolic process 5.498782e-5
GO:0018352 protein-pyridoxal-5-phosphate linkage 5.498782e-5
GO:0000964 mitochondrial RNA 5'-end processing 5.498782e-5
GO:0016082 synaptic vesicle priming 5.825721e-5
GO:0051261 protein depolymerization 6.081229e-5
GO:0070537 histone H2A K63-linked deubiquitination 6.503818e-5
GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 6.875841e-5
GO:0009817 defense response to fungus, incompatible interaction 6.875841e-5
GO:0090086 negative regulation of protein deubiquitination 6.923214e-5
GO:0006173 dADP biosynthetic process 6.923214e-5
GO:0090231 regulation of spindle checkpoint 6.931715e-5
GO:0060560 developmental growth involved in morphogenesis 7.004584e-5
GO:0048075 positive regulation of eye pigmentation 7.093892e-5
GO:0045841 negative regulation of mitotic metaphase/anaphase transition 8.048225e-5
GO:0021603 cranial nerve formation 8.407294e-5
GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein 8.589728e-5
GO:0006682 galactosylceramide biosynthetic process 9.383044e-5
GO:0031081 nuclear pore distribution 1.099125e-4
GO:0043316 cytotoxic T cell degranulation 1.109111e-4
GO:0032096 negative regulation of response to food 1.131812e-4
GO:0021511 spinal cord patterning 1.207624e-4
GO:0031848 protection from non-homologous end joining at telomere 1.210428e-4
GO:0032740 positive regulation of interleukin-17 production 1.215070e-4
GO:0046730 induction of host immune response by virus 1.250924e-4
GO:0043249 erythrocyte maturation 1.275446e-4
GO:0032108 negative regulation of response to nutrient levels 1.276138e-4
GO:0034508 centromere complex assembly 1.277937e-4
GO:0032099 negative regulation of appetite 1.277937e-4
GO:0051148 negative regulation of muscle cell differentiation 1.289908e-4
GO:0045116 protein neddylation 1.425757e-4
GO:0048102 autophagic cell death 1.425757e-4
GO:0006538 glutamate catabolic process 1.425757e-4
GO:0033034 positive regulation of myeloid cell apoptosis 1.512208e-4
GO:0090311 regulation of protein deacetylation 1.541805e-4
GO:0043633 polyadenylation-dependent RNA catabolic process 1.623632e-4
GO:0000965 mitochondrial RNA 3'-end processing 1.623632e-4
GO:0000958 mitochondrial mRNA catabolic process 1.623632e-4
GO:0000962 positive regulation of mitochondrial RNA catabolic process 1.623632e-4
GO:0044089 positive regulation of cellular component biogenesis 1.625710e-4
GO:0043628 ncRNA 3'-end processing 1.654562e-4
GO:0016058 maintenance of membrane potential in photoreceptor cell by rhodopsin mediated signaling 1.759561e-4
GO:0022400 regulation of rhodopsin mediated signaling pathway 1.759561e-4
GO:0006208 pyrimidine base catabolic process 1.863446e-4
GO:0042509 regulation of tyrosine phosphorylation of STAT protein 1.989164e-4
GO:0048639 positive regulation of developmental growth 2.126581e-4
GO:0010891 negative regulation of sequestering of triglyceride 2.148007e-4
GO:0015812 gamma-aminobutyric acid transport 2.166933e-4
GO:0060603 mammary gland duct morphogenesis 2.182948e-4
GO:0006273 lagging strand elongation 2.230210e-4
GO:0030516 regulation of axon extension 2.364681e-4
GO:0021599 abducens nerve formation 2.445596e-4
GO:0016191 synaptic vesicle uncoating 2.445596e-4
GO:0007634 optokinetic behavior 2.445596e-4
GO:0015809 arginine transport 2.536863e-4
GO:0000089 mitotic metaphase 2.640831e-4
GO:0000085 G2 phase of mitotic cell cycle 2.654731e-4
GO:0061101 neuroendocrine cell differentiation 2.761768e-4
GO:0072361 regulation of glycolysis by regulation of transcription from RNA polymerase II promoter 2.792394e-4
GO:0050805 negative regulation of synaptic transmission 2.830397e-4
GO:0006369 termination of RNA polymerase II transcription 2.904741e-4
GO:0051898 negative regulation of protein kinase B signaling cascade 2.919720e-4
GO:0032331 negative regulation of chondrocyte differentiation 2.969219e-4
GO:0031536 positive regulation of exit from mitosis 3.079658e-4
GO:0001522 pseudouridine synthesis 3.079658e-4
GO:0042117 monocyte activation 3.298856e-4
GO:0071105 response to interleukin-11 3.478891e-4
GO:0043653 mitochondrial fragmentation involved in apoptosis 3.567228e-4
GO:0030853 negative regulation of granulocyte differentiation 3.589367e-4
GO:0003140 determination of left/right asymmetry in lateral mesoderm 3.669391e-4
GO:0051322 anaphase 3.687249e-4
GO:0006268 DNA unwinding involved in replication 3.744145e-4
GO:0010823 negative regulation of mitochondrion organization 3.779253e-4
GO:0046113 nucleobase catabolic process 3.783958e-4
GO:0021513 spinal cord dorsal/ventral patterning 3.828343e-4
GO:0051965 positive regulation of synapse assembly 4.054306e-4
GO:0000959 mitochondrial RNA metabolic process 4.148846e-4
GO:0001558 regulation of cell growth 4.262697e-4
GO:0007000 nucleolus organization 4.384864e-4
GO:0000022 mitotic spindle elongation 4.384864e-4
GO:0034623 cellular macromolecular complex disassembly 4.411470e-4
GO:0016139 glycoside catabolic process 4.455775e-4
GO:0010936 negative regulation of macrophage cytokine production 4.540984e-4
GO:0070358 actin polymerization-dependent cell motility 4.634194e-4
GO:0002309 T cell proliferation involved in immune response 4.719572e-4
GO:0042516 regulation of tyrosine phosphorylation of Stat3 protein 4.769353e-4
GO:0009451 RNA modification 4.885772e-4
GO:0002513 tolerance induction to self antigen 5.060161e-4
GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter 5.274818e-4
GO:0071173 spindle assembly checkpoint 5.317449e-4
GO:0050432 catecholamine secretion 5.327348e-4
GO:0061102 stomach neuroendocrine cell differentiation 5.371919e-4
GO:0061100 lung neuroendocrine cell differentiation 5.371919e-4
GO:0071259 cellular response to magnetism 5.371919e-4
GO:0061104 adrenal chromaffin cell differentiation 5.371919e-4
GO:0061103 carotid body glomus cell differentiation 5.371919e-4
GO:0003359 noradrenergic neuron fate commitment 5.371919e-4
GO:0060165 regulation of timing of subpallium neuron differentiation 5.371919e-4
GO:0007400 neuroblast fate determination 5.371919e-4
GO:0048073 regulation of eye pigmentation 5.371919e-4
GO:0060163 subpallium neuron fate commitment 5.371919e-4
GO:0008334 histone mRNA metabolic process 5.381636e-4
GO:0007051 spindle organization 5.542627e-4
GO:0071174 mitotic cell cycle spindle checkpoint 5.669992e-4
GO:0021569 rhombomere 3 development 5.722740e-4
GO:0032984 macromolecular complex disassembly 5.755198e-4
GO:0031577 spindle checkpoint 5.968213e-4
GO:2000534 positive regulation of renal albumin absorption 5.989993e-4
GO:2000481 positive regulation of cAMP-dependent protein kinase activity 5.989993e-4
GO:0070994 detection of oxidative stress 5.989993e-4
GO:2000461 negative regulation of eukaryotic cell surface binding 5.989993e-4
GO:2000478 positive regulation of metanephric glomerular visceral epithelial cell development 5.989993e-4
GO:0048627 myoblast development 6.014919e-4
GO:0007094 mitotic cell cycle spindle assembly checkpoint 6.116987e-4
GO:0035880 embryonic nail plate morphogenesis 6.244621e-4
GO:0006625 protein targeting to peroxisome 6.263872e-4
GO:0035625 epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway 6.512660e-4
GO:0045649 regulation of macrophage differentiation 6.789031e-4
GO:0043129 surfactant homeostasis 6.849619e-4
GO:0052509 positive regulation by symbiont of host defense response 6.905140e-4
GO:0045820 negative regulation of glycolysis 7.180013e-4
GO:0006379 mRNA cleavage 7.180013e-4
GO:0021623 oculomotor nerve formation 7.200958e-4
GO:0003409 optic cup structural organization 7.200958e-4
GO:0003404 optic vesicle morphogenesis 7.200958e-4
GO:0061387 regulation of extent of cell growth 7.361449e-4
GO:0002418 immune response to tumor cell 7.436272e-4
GO:0060465 pharynx development 7.436272e-4
GO:0043624 cellular protein complex disassembly 7.691840e-4
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 7.709876e-4
GO:0071281 cellular response to iron ion 7.745258e-4
GO:0051970 negative regulation of transmission of nerve impulse 7.892388e-4
GO:2000340 positive regulation of chemokine (C-X-C motif) ligand 1 production 7.987271e-4
GO:0035665 TIRAP-dependent toll-like receptor 4 signaling pathway 7.987271e-4
GO:0006427 histidyl-tRNA aminoacylation 7.987271e-4
GO:0032738 positive regulation of interleukin-15 production 7.987271e-4
GO:0048486 parasympathetic nervous system development 7.988989e-4
GO:0034080 CenH3-containing nucleosome assembly at centromere 7.988989e-4
GO:0072363 regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter 8.177327e-4
GO:0072366 regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter 8.177327e-4
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.177327e-4
GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport 8.177327e-4
GO:0051926 negative regulation of calcium ion transport 8.314330e-4
GO:0032812 positive regulation of epinephrine secretion 8.392231e-4
GO:0070253 somatostatin secretion 8.392231e-4
GO:0046683 response to organophosphorus 8.436078e-4
GO:0021545 cranial nerve development 8.496552e-4
GO:0031063 regulation of histone deacetylation 8.609251e-4
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 8.671099e-4
GO:0045653 negative regulation of megakaryocyte differentiation 8.716132e-4
GO:0060876 semicircular canal formation 9.165486e-4
GO:0034137 positive regulation of toll-like receptor 2 signaling pathway 9.165486e-4
GO:0070574 cadmium ion transmembrane transport 9.271345e-4
GO:0017085 response to insecticide 9.440765e-4
GO:0032845 negative regulation of homeostatic process 9.441110e-4
GO:0007228 positive regulation of hh target transcription factor activity 9.522179e-4
GO:0043981 histone H4-K5 acetylation 9.703993e-4
GO:0043982 histone H4-K8 acetylation 9.703993e-4
GO:0090312 positive regulation of protein deacetylation 9.851551e-4
GO:0048298 positive regulation of isotype switching to IgA isotypes 1.002847e-3
GO:0043932 ossification involved in bone remodeling 1.005937e-3
GO:0046724 oxalic acid secretion 1.027074e-3
GO:0019265 glycine biosynthetic process, by transamination of glyoxylate 1.027074e-3
GO:0043241 protein complex disassembly 1.031316e-3
GO:0021938 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation 1.049466e-3
GO:0015889 cobalamin transport 1.049466e-3
GO:0034436 glycoprotein transport 1.058424e-3
GO:0090085 regulation of protein deubiquitination 1.058424e-3
GO:0009720 detection of hormone stimulus 1.058424e-3
GO:0030573 bile acid catabolic process 1.067874e-3
GO:0060459 left lung development 1.079875e-3
GO:0001916 positive regulation of T cell mediated cytotoxicity 1.103409e-3
GO:0032660 regulation of interleukin-17 production 1.157529e-3
GO:0018108 peptidyl-tyrosine phosphorylation 1.175510e-3
GO:0035115 embryonic forelimb morphogenesis 1.186386e-3
GO:0042998 positive regulation of Golgi to plasma membrane protein transport 1.190827e-3
GO:0048008 platelet-derived growth factor receptor signaling pathway 1.211093e-3
GO:0010739 positive regulation of protein kinase A signaling cascade 1.224320e-3
GO:2000077 negative regulation of type B pancreatic cell development 1.286630e-3
GO:0006420 arginyl-tRNA aminoacylation 1.286630e-3
GO:0042520 positive regulation of tyrosine phosphorylation of Stat4 protein 1.310358e-3
GO:0043574 peroxisomal transport 1.326104e-3
GO:0000731 DNA synthesis involved in DNA repair 1.327876e-3
GO:0045839 negative regulation of mitosis 1.334397e-3
GO:0031055 chromatin remodeling at centromere 1.345820e-3
GO:2000062 negative regulation of ureter smooth muscle cell differentiation 1.355073e-3
GO:2000063 positive regulation of ureter smooth muscle cell differentiation 1.355073e-3
GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development 1.355073e-3
GO:2000358 positive regulation of kidney smooth muscle cell differentiation 1.355073e-3
GO:2000357 negative regulation of kidney smooth muscle cell differentiation 1.355073e-3
GO:0080125 multicellular structure septum development 1.355073e-3
GO:0007502 digestive tract mesoderm development 1.355073e-3
GO:0060783 mesenchymal smoothened signaling pathway involved in prostate gland development 1.355073e-3
GO:0014858 positive regulation of skeletal muscle cell proliferation 1.355073e-3
GO:0060782 regulation of mesenchymal cell proliferation involved in prostate gland development 1.355073e-3
GO:0046534 positive regulation of photoreceptor cell differentiation 1.355073e-3
GO:0022037 metencephalon development 1.356395e-3
GO:0070206 protein trimerization 1.398495e-3
GO:0021530 spinal cord oligodendrocyte cell fate specification 1.423822e-3
GO:0022616 DNA strand elongation 1.435988e-3
GO:0060447 bud outgrowth involved in lung branching 1.460716e-3
GO:0008361 regulation of cell size 1.497281e-3
GO:0031645 negative regulation of neurological system process 1.514767e-3
GO:0030071 regulation of mitotic metaphase/anaphase transition 1.533228e-3
GO:0018212 peptidyl-tyrosine modification 1.538934e-3
GO:0070172 positive regulation of tooth mineralization 1.573638e-3
GO:0006013 mannose metabolic process 1.588802e-3
GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter 1.596990e-3
GO:0021546 rhombomere development 1.617242e-3
GO:0070207 protein homotrimerization 1.617557e-3
GO:0019083 viral transcription 1.653667e-3
GO:0018065 protein-cofactor linkage 1.691000e-3
GO:0010887 negative regulation of cholesterol storage 1.698060e-3
GO:0060579 ventral spinal cord interneuron fate commitment 1.699102e-3
GO:0006272 leading strand elongation 1.708729e-3
GO:0046532 regulation of photoreceptor cell differentiation 1.721607e-3
GO:0051586 positive regulation of dopamine uptake 1.768199e-3
GO:0010722 regulation of ferrochelatase activity 1.768199e-3
GO:0009189 deoxyribonucleoside diphosphate biosynthetic process 1.789576e-3
GO:0006528 asparagine metabolic process 1.789576e-3
GO:0072298 regulation of metanephric glomerulus development 1.812750e-3
GO:0045684 positive regulation of epidermis development 1.813801e-3
GO:0044341 sodium-dependent phosphate transport 1.820138e-3
GO:0010523 negative regulation of calcium ion transport into cytosol 1.834717e-3
GO:0010043 response to zinc ion 1.877550e-3
GO:0045604 regulation of epidermal cell differentiation 1.881569e-3
GO:0010637 negative regulation of mitochondrial fusion 1.945116e-3
GO:0071279 cellular response to cobalt ion 1.945116e-3
GO:0030311 poly-N-acetyllactosamine biosynthetic process 1.945116e-3
GO:0001957 intramembranous ossification 1.965664e-3
GO:0060659 nipple sheath formation 1.977622e-3
GO:0060649 mammary gland bud elongation 1.977622e-3
GO:0043525 positive regulation of neuron apoptosis 1.983835e-3
GO:0000712 resolution of meiotic recombination intermediates 1.996118e-3
GO:0007019 microtubule depolymerization 2.036111e-3
GO:0010832 negative regulation of myotube differentiation 2.040480e-3
GO:0045776 negative regulation of blood pressure 2.062724e-3
GO:0018027 peptidyl-lysine dimethylation 2.131984e-3
GO:0009153 purine deoxyribonucleotide biosynthetic process 2.154971e-3
GO:0031860 telomeric 3' overhang formation 2.176356e-3
GO:2000009 negative regulation of protein localization at cell surface 2.176356e-3
GO:0071422 succinate transmembrane transport 2.216892e-3
GO:0042489 negative regulation of odontogenesis of dentine-containing tooth 2.302978e-3
GO:0014051 gamma-aminobutyric acid secretion 2.302978e-3
GO:0072136 metanephric mesenchymal cell proliferation involved in metanephros development 2.416355e-3
GO:0061003 positive regulation of dendritic spine morphogenesis 2.416355e-3
GO:0090084 negative regulation of inclusion body assembly 2.487436e-3
GO:0031657 regulation of cyclin-dependent protein kinase activity involved in G1/S 2.525576e-3
GO:0009066 aspartate family amino acid metabolic process 2.578852e-3
GO:0021592 fourth ventricle development 2.632474e-3
GO:0046501 protoporphyrinogen IX metabolic process 2.679871e-3
GO:0071585 detoxification of cadmium ion 2.689748e-3
GO:0006270 DNA-dependent DNA replication initiation 2.692537e-3
GO:0048840 otolith development 2.736897e-3
GO:0048714 positive regulation of oligodendrocyte differentiation 2.874974e-3
GO:0071549 cellular response to dexamethasone stimulus 2.889922e-3
GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter 2.891072e-3
GO:0000090 mitotic anaphase 2.938302e-3
GO:0006271 DNA strand elongation involved in DNA replication 2.964323e-3
GO:0034616 response to laminar fluid shear stress 2.964323e-3
GO:0045005 maintenance of fidelity involved in DNA-dependent DNA replication 3.053008e-3
GO:0070060 'de novo' actin filament nucleation 3.073662e-3
GO:0006529 asparagine biosynthetic process 3.073662e-3
GO:0045200 establishment of neuroblast polarity 3.093603e-3
GO:0009229 thiamine diphosphate biosynthetic process 3.093603e-3
GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response 3.093603e-3
GO:0002719 negative regulation of cytokine production involved in immune response 3.112119e-3
GO:0046425 regulation of JAK-STAT cascade 3.118795e-3
GO:0060516 primary prostatic bud elongation 3.120438e-3
GO:0071850 mitotic cell cycle arrest 3.215995e-3
GO:0070447 positive regulation of oligodendrocyte progenitor proliferation 3.215995e-3
GO:0070863 positive regulation of protein exit from endoplasmic reticulum 3.303992e-3
GO:0045792 negative regulation of cell size 3.347794e-3
GO:0090232 positive regulation of spindle checkpoint 3.347794e-3
GO:0006546 glycine catabolic process 3.347794e-3
GO:0048859 formation of anatomical boundary 3.370931e-3
GO:0007418 ventral midline development 3.370931e-3
GO:0001553 luteinization 3.391321e-3
GO:0018026 peptidyl-lysine monomethylation 3.411775e-3
GO:0030308 negative regulation of cell growth 3.446284e-3
GO:0021521 ventral spinal cord interneuron specification 3.453076e-3
GO:0031297 replication fork processing 3.464605e-3
GO:0019049 evasion of host defenses by virus 3.464605e-3
GO:0042482 positive regulation of odontogenesis 3.502283e-3
GO:0070925 organelle assembly 3.535627e-3
GO:0015701 bicarbonate transport 3.579874e-3
GO:0034214 protein hexamerization 3.588819e-3
GO:0033058 directional locomotion 3.588819e-3
GO:0019058 viral infectious cycle 3.601039e-3
GO:0006260 DNA replication 3.632540e-3
GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus 3.634728e-3
GO:0060611 mammary gland fat development 3.634728e-3
GO:0006415 translational termination 3.671608e-3
GO:0019695 choline metabolic process 3.680622e-3
GO:0060349 bone morphogenesis 3.702296e-3
GO:0060444 branching involved in mammary gland duct morphogenesis 3.709831e-3
GO:0043268 positive regulation of potassium ion transport 3.779267e-3
GO:0016233 telomere capping 3.862735e-3
GO:0033004 negative regulation of mast cell activation 3.910611e-3
GO:0031427 response to methotrexate 3.923223e-3
GO:0035458 cellular response to interferon-beta 3.926343e-3
GO:0031123 RNA 3'-end processing 3.952169e-3
GO:0002052 positive regulation of neuroblast proliferation 4.017832e-3
GO:0021549 cerebellum development 4.019104e-3
GO:0002369 T cell cytokine production 4.023294e-3
GO:0010742 macrophage derived foam cell differentiation 4.023294e-3
GO:0031125 rRNA 3'-end processing 4.040336e-3
GO:0032571 response to vitamin K 4.040336e-3
GO:0021568 rhombomere 2 development 4.040336e-3
GO:0016539 intein-mediated protein splicing 4.040336e-3
GO:0009263 deoxyribonucleotide biosynthetic process 4.087288e-3
GO:0006105 succinate metabolic process 4.107183e-3
GO:0016560 protein import into peroxisome matrix, docking 4.130400e-3
GO:0060381 positive regulation of single-stranded telomeric DNA binding 4.130400e-3
GO:0032463 negative regulation of protein homooligomerization 4.136237e-3
GO:0090218 positive regulation of lipid kinase activity 4.196352e-3
GO:0033205 cell cycle cytokinesis 4.208411e-3
GO:0021903 rostrocaudal neural tube patterning 4.228068e-3
GO:0032864 activation of Cdc42 GTPase activity 4.316854e-3
GO:0051320 S phase 4.346831e-3
GO:0050769 positive regulation of neurogenesis 4.431811e-3
GO:0048705 skeletal system morphogenesis 4.547801e-3
GO:0051532 regulation of NFAT protein import into nucleus 4.550372e-3
GO:0006828 manganese ion transport 4.550372e-3
GO:0060484 lung-associated mesenchyme development 4.559578e-3
GO:0045085 negative regulation of interleukin-2 biosynthetic process 4.574026e-3
GO:0042780 tRNA 3'-end processing 4.614312e-3
GO:0010734 negative regulation of protein glutathionylation 4.614312e-3
GO:0001778 plasma membrane repair 4.620432e-3
GO:0070086 ubiquitin-dependent endocytosis 4.627018e-3
GO:0050931 pigment cell differentiation 4.702177e-3
GO:0030917 midbrain-hindbrain boundary development 4.758917e-3
GO:0045682 regulation of epidermis development 4.796301e-3
GO:0006607 NLS-bearing substrate import into nucleus 4.807264e-3
GO:0021697 cerebellar cortex formation 4.817974e-3
GO:0044070 regulation of anion transport 4.863494e-3
GO:0032922 circadian regulation of gene expression 4.886460e-3
GO:0021526 medial motor column neuron differentiation 4.902694e-3
GO:0021658 rhombomere 3 morphogenesis 4.933848e-3
GO:0015886 heme transport 5.089333e-3
GO:0008210 estrogen metabolic process 5.095822e-3
GO:0048808 male genitalia morphogenesis 5.133366e-3
GO:0007262 STAT protein import into nucleus 5.135847e-3
GO:0021523 somatic motor neuron differentiation 5.135847e-3
GO:0005983 starch catabolic process 5.135925e-3
GO:0006172 ADP biosynthetic process 5.159280e-3
GO:0000966 RNA 5'-end processing 5.159280e-3
GO:0030953 astral microtubule organization 5.219233e-3
GO:0002357 defense response to tumor cell 5.325004e-3
GO:0008057 eye pigment granule organization 5.468644e-3
GO:0046031 ADP metabolic process 5.482145e-3
GO:0015844 monoamine transport 5.482957e-3
GO:0033007 negative regulation of mast cell activation involved in immune response 5.524184e-3
GO:0001579 medium-chain fatty acid transport 5.583526e-3
GO:0060648 mammary gland bud morphogenesis 5.603128e-3
GO:0031065 positive regulation of histone deacetylation 5.755708e-3
GO:0030852 regulation of granulocyte differentiation 5.836010e-3
GO:0035284 brain segmentation 5.993242e-3
GO:0072075 metanephric mesenchyme development 6.049360e-3
GO:0051154 negative regulation of striated muscle cell differentiation 6.087865e-3
GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway 6.132594e-3
GO:0021587 cerebellum morphogenesis 6.239969e-3
GO:0003416 endochondral bone growth 6.242240e-3
GO:0045616 regulation of keratinocyte differentiation 6.277464e-3
GO:0016137 glycoside metabolic process 6.484638e-3
GO:0015802 basic amino acid transport 6.565195e-3
GO:0009186 deoxyribonucleoside diphosphate metabolic process 6.617607e-3
GO:0030309 poly-N-acetyllactosamine metabolic process 6.688732e-3
GO:0048676 axon extension involved in development 6.698452e-3
GO:0050873 brown fat cell differentiation 6.699812e-3
GO:0072500 negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor 6.713499e-3
GO:0002115 store-operated calcium entry 6.713499e-3
GO:0051937 catecholamine transport 6.729126e-3
GO:0021514 ventral spinal cord interneuron differentiation 6.950944e-3
GO:0090201 negative regulation of release of cytochrome c from mitochondria 6.976440e-3
GO:0006303 double-strand break repair via nonhomologous end joining 6.976440e-3
GO:0042320 regulation of circadian sleep/wake cycle, REM sleep 7.058743e-3
GO:0002076 osteoblast development 7.088888e-3
GO:0042487 regulation of odontogenesis of dentine-containing tooth 7.177333e-3
GO:0003105 negative regulation of glomerular filtration 7.203547e-3
GO:0043320 natural killer cell degranulation 7.236779e-3
GO:0021558 trochlear nerve development 7.236779e-3
GO:0006836 neurotransmitter transport 7.266065e-3
GO:0043983 histone H4-K12 acetylation 7.358811e-3
GO:0060602 branch elongation of an epithelium 7.420618e-3
GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation 7.510580e-3
GO:0022415 viral reproductive process 7.516724e-3
GO:0072060 outer medullary collecting duct development 7.557900e-3
GO:0072061 inner medullary collecting duct development 7.557900e-3
GO:0016332 establishment or maintenance of polarity of embryonic epithelium 7.557900e-3
GO:0060768 regulation of epithelial cell proliferation involved in prostate gland development 7.600713e-3
GO:0006401 RNA catabolic process 7.608025e-3
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 7.638004e-3
GO:0006221 pyrimidine nucleotide biosynthetic process 7.680213e-3
GO:0045650 negative regulation of macrophage differentiation 7.853433e-3
GO:0021559 trigeminal nerve development 7.861912e-3
GO:0060535 trachea cartilage morphogenesis 8.093918e-3
GO:2000466 negative regulation of glycogen (starch) synthase activity 8.100058e-3
GO:0060242 contact inhibition 8.100058e-3
GO:0021533 cell differentiation in hindbrain 8.105529e-3
GO:0045618 positive regulation of keratinocyte differentiation 8.314318e-3
GO:0048818 positive regulation of hair follicle maturation 8.314318e-3
GO:0003198 epithelial to mesenchymal transition involved in endocardial cushion formation 8.314318e-3
GO:0070845 polyubiquitinated misfolded protein transport 8.387440e-3
GO:0009436 glyoxylate catabolic process 8.389402e-3
GO:0070170 regulation of tooth mineralization 8.459906e-3
GO:0043089 positive regulation of Cdc42 GTPase activity 8.481756e-3
GO:0045345 positive regulation of MHC class I biosynthetic process 8.679398e-3
GO:0001836 release of cytochrome c from mitochondria 8.699592e-3
GO:0006353 transcription termination, DNA-dependent 8.801539e-3
GO:0045066 regulatory T cell differentiation 8.820488e-3
GO:0060253 negative regulation of glial cell proliferation 8.992013e-3
GO:0061180 mammary gland epithelium development 8.996625e-3
GO:0070723 response to cholesterol 9.072373e-3
GO:0009265 2'-deoxyribonucleotide biosynthetic process 9.094924e-3
GO:0006390 transcription from mitochondrial promoter 9.246797e-3
GO:0010869 regulation of receptor biosynthetic process 9.295772e-3
GO:0002071 glandular epithelial cell maturation 9.342247e-3
GO:0000917 barrier septum formation 9.342247e-3
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 9.466464e-3
GO:0031662 positive regulation of cyclin-dependent protein kinase activity involved in G2/M 9.530652e-3
GO:0070194 synaptonemal complex disassembly 9.530652e-3
GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway 9.668510e-3
GO:0060923 cardiac muscle cell fate commitment 9.698747e-3
GO:0021678 third ventricle development 9.698747e-3
GO:0035313 wound healing, spreading of epidermal cells 9.709167e-3
GO:0034728 nucleosome organization 9.768247e-3
GO:0010821 regulation of mitochondrion organization 9.769275e-3
GO:0010944 negative regulation of transcription by competitive promoter binding 9.784857e-3
GO:0060359 response to ammonium ion 9.792952e-3
GO:0050716 positive regulation of interleukin-1 secretion 9.855040e-3
GO:0000093 mitotic telophase 9.925068e-3
GO:0006402 mRNA catabolic process 9.962436e-3
GO:0005978 glycogen biosynthetic process 9.987531e-3
GO:0010452 histone H3-K36 methylation 1.006924e-2
GO:0000271 polysaccharide biosynthetic process 1.012127e-2
GO:0018022 peptidyl-lysine methylation 1.024238e-2
GO:0005993 trehalose catabolic process 1.037645e-2
GO:0016559 peroxisome fission 1.037645e-2
GO:0042273 ribosomal large subunit biogenesis 1.043942e-2
GO:0033032 regulation of myeloid cell apoptosis 1.067165e-2
GO:0033504 floor plate development 1.072030e-2
GO:0032095 regulation of response to food 1.072973e-2
GO:0020028 hemoglobin import 1.094037e-2
GO:0035659 Wnt receptor signaling pathway involved in wound healing, spreading of epidermal cells 1.114401e-2
GO:0014719 satellite cell activation 1.114401e-2
GO:0051795 positive regulation of catagen 1.128677e-2
GO:0019227 neuronal action potential propagation 1.137168e-2
GO:0001561 fatty acid alpha-oxidation 1.140203e-2
GO:0045343 regulation of MHC class I biosynthetic process 1.151356e-2
GO:0042488 positive regulation of odontogenesis of dentine-containing tooth 1.152941e-2
GO:0033133 positive regulation of glucokinase activity 1.163294e-2
GO:0021575 hindbrain morphogenesis 1.165367e-2
GO:2001044 regulation of integrin-mediated signaling pathway 1.174481e-2
GO:0032474 otolith morphogenesis 1.174481e-2
GO:0006741 NADP biosynthetic process 1.174481e-2
GO:0021532 neural tube patterning 1.200423e-2
GO:0006333 chromatin assembly or disassembly 1.208699e-2
GO:0031659 positive regulation of cyclin-dependent protein kinase activity involved in G1/S 1.209366e-2
GO:0030318 melanocyte differentiation 1.213336e-2
GO:0009636 response to toxin 1.219456e-2
GO:0021571 rhombomere 5 development 1.247672e-2


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0060923 cardiac muscle cell fate commitment 2.086099e-10
GO:0060911 cardiac cell fate commitment 1.313870e-8
GO:0090083 regulation of inclusion body assembly 2.052600e-8
GO:0060307 regulation of ventricular cardiomyocyte membrane repolarization 3.248306e-8
GO:0060299 negative regulation of sarcomere organization 3.248306e-8
GO:0060932 His-Purkinje system cell differentiation 4.692870e-8
GO:0060926 pacemaker cell development 4.692870e-8
GO:0060920 pacemaker cell differentiation 9.010162e-8
GO:0010159 specification of organ position 1.539555e-7
GO:0045416 positive regulation of interleukin-8 biosynthetic process 1.066657e-6
GO:0090084 negative regulation of inclusion body assembly 1.101375e-6
GO:0003163 sinoatrial node development 1.358790e-6
GO:0003167 atrioventricular bundle cell differentiation 1.562217e-6
GO:0060931 sinoatrial node cell development 1.562217e-6
GO:0032094 response to food 1.690144e-6
GO:0006012 galactose metabolic process 1.722919e-6
GO:0060047 heart contraction 1.742472e-6
GO:0060921 sinoatrial node cell differentiation 2.723834e-6
GO:0005981 regulation of glycogen catabolic process 2.902760e-6
GO:0070842 aggresome assembly 4.094571e-6
GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 5.205097e-6
GO:0003161 cardiac conduction system development 7.116796e-6
GO:0034260 negative regulation of GTPase activity 7.950292e-6
GO:0060048 cardiac muscle contraction 8.768935e-6
GO:0034421 post-translational protein acetylation 9.748536e-6
GO:0030382 sperm mitochondrion organization 1.041893e-5
GO:0003166 bundle of His development 1.476667e-5
GO:0021586 pons maturation 1.526136e-5
GO:0090231 regulation of spindle checkpoint 1.738287e-5
GO:0033005 positive regulation of mast cell activation 1.903001e-5
GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 2.089295e-5
GO:0070430 positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 2.089295e-5
GO:0045362 positive regulation of interleukin-1 biosynthetic process 2.089295e-5
GO:0032707 negative regulation of interleukin-23 production 2.089295e-5
GO:0032757 positive regulation of interleukin-8 production 2.154938e-5
GO:0043306 positive regulation of mast cell degranulation 2.426067e-5
GO:0034509 centromeric core chromatin assembly 2.432284e-5
GO:0034080 CenH3-containing nucleosome assembly at centromere 2.432284e-5
GO:0019285 glycine betaine biosynthetic process from choline 2.745192e-5
GO:0032275 luteinizing hormone secretion 3.743055e-5
GO:0046884 follicle-stimulating hormone secretion 3.743055e-5
GO:0003015 heart process 3.859303e-5
GO:0042339 keratan sulfate metabolic process 4.494210e-5
GO:0045414 regulation of interleukin-8 biosynthetic process 4.880225e-5
GO:0018364 peptidyl-glutamine methylation 5.095311e-5
GO:0032647 regulation of interferon-alpha production 5.645614e-5
GO:0032648 regulation of interferon-beta production 5.996517e-5
GO:0032218 riboflavin transport 6.042099e-5
GO:0043302 positive regulation of leukocyte degranulation 6.690968e-5
GO:0035802 adrenal cortex formation 6.700499e-5
GO:0045359 positive regulation of interferon-beta biosynthetic process 8.335831e-5
GO:0042398 cellular modified amino acid biosynthetic process 9.246972e-5
GO:0090086 negative regulation of protein deubiquitination 1.163433e-4
GO:2000491 positive regulation of hepatic stellate cell activation 1.304200e-4
GO:0021935 cerebellar granule cell precursor tangential migration 1.304200e-4
GO:0051769 regulation of nitric-oxide synthase biosynthetic process 1.308520e-4
GO:0051148 negative regulation of muscle cell differentiation 1.313793e-4
GO:0090192 regulation of glomerulus development 1.415679e-4
GO:0019255 glucose 1-phosphate metabolic process 1.608371e-4
GO:0033578 protein glycosylation in Golgi 1.631719e-4
GO:0045964 positive regulation of dopamine metabolic process 1.761115e-4
GO:0021933 radial glia guided migration of cerebellar granule cell 1.803254e-4
GO:0080164 regulation of nitric oxide metabolic process 1.803254e-4
GO:0006825 copper ion transport 2.039550e-4
GO:0001880 Mullerian duct regression 2.186412e-4
GO:0045749 negative regulation of S phase of mitotic cell cycle 2.902402e-4
GO:0051586 positive regulation of dopamine uptake 2.979498e-4
GO:0060216 definitive hemopoiesis 3.281213e-4
GO:0051775 response to redox state 3.350617e-4
GO:0008355 olfactory learning 3.350617e-4
GO:0006409 tRNA export from nucleus 3.582389e-4
GO:0006427 histidyl-tRNA aminoacylation 3.582389e-4
GO:0031329 regulation of cellular catabolic process 3.610868e-4
GO:0007405 neuroblast proliferation 3.802538e-4
GO:0051150 regulation of smooth muscle cell differentiation 4.033242e-4
GO:0072298 regulation of metanephric glomerulus development 4.388178e-4
GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint 4.524721e-4
GO:0006413 translational initiation 4.559308e-4
GO:0021998 neural plate mediolateral regionalization 4.574470e-4
GO:0048352 paraxial mesoderm structural organization 4.574470e-4
GO:0048672 positive regulation of collateral sprouting 4.980384e-4
GO:0032479 regulation of type I interferon production 5.182391e-4
GO:0006089 lactate metabolic process 5.186043e-4
GO:0032781 positive regulation of ATPase activity 5.267100e-4
GO:0033121 regulation of purine nucleotide catabolic process 5.996707e-4
GO:0072125 negative regulation of glomerular mesangial cell proliferation 6.395157e-4
GO:0045357 regulation of interferon-beta biosynthetic process 6.598751e-4
GO:0016559 peroxisome fission 6.671652e-4
GO:0016557 peroxisome membrane biogenesis 7.501122e-4
GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 7.869184e-4
GO:0006030 chitin metabolic process 8.074323e-4
GO:0002418 immune response to tumor cell 8.180551e-4
GO:0090138 regulation of actin cytoskeleton organization by cell-cell adhesion 8.180551e-4
GO:0051103 DNA ligation involved in DNA repair 8.317026e-4
GO:0032849 positive regulation of cellular pH reduction 8.463357e-4
GO:2000426 negative regulation of apoptotic cell clearance 8.481007e-4
GO:0060821 inactivation of X chromosome by DNA methylation 8.636409e-4
GO:0072355 histone H3-T3 phosphorylation 8.636409e-4
GO:0006258 UDP-glucose catabolic process 8.636409e-4
GO:0016578 histone deubiquitination 9.099897e-4
GO:0035115 embryonic forelimb morphogenesis 9.155825e-4
GO:2000466 negative regulation of glycogen (starch) synthase activity 9.582277e-4
GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter 1.011046e-3
GO:0071901 negative regulation of protein serine/threonine kinase activity 1.061562e-3
GO:0015670 carbon dioxide transport 1.075018e-3
GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis 1.077179e-3
GO:0048670 regulation of collateral sprouting 1.122847e-3
GO:2001076 positive regulation of metanephric ureteric bud development 1.123680e-3
GO:0007356 thorax and anterior abdomen determination 1.123680e-3
GO:0072302 negative regulation of metanephric glomerular mesangial cell proliferation 1.123680e-3
GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway 1.188836e-3
GO:0035412 regulation of catenin import into nucleus 1.207048e-3
GO:0009081 branched chain family amino acid metabolic process 1.232963e-3
GO:0030539 male genitalia development 1.234763e-3
GO:0022904 respiratory electron transport chain 1.269853e-3
GO:0060060 post-embryonic retina morphogenesis in camera-type eye 1.344247e-3
GO:0007090 regulation of S phase of mitotic cell cycle 1.357354e-3
GO:0043407 negative regulation of MAP kinase activity 1.403621e-3
GO:0090287 regulation of cellular response to growth factor stimulus 1.413236e-3
GO:0043457 regulation of cellular respiration 1.429080e-3
GO:0021502 neural fold elevation formation 1.429080e-3
GO:0000212 meiotic spindle organization 1.429080e-3
GO:0032274 gonadotropin secretion 1.446784e-3
GO:0032727 positive regulation of interferon-alpha production 1.449304e-3
GO:0045662 negative regulation of myoblast differentiation 1.460525e-3
GO:0051386 regulation of nerve growth factor receptor signaling pathway 1.462917e-3
GO:0006658 phosphatidylserine metabolic process 1.462917e-3
GO:0006266 DNA ligation 1.462917e-3
GO:0035417 negative regulation of mitotic prometaphase 1.556272e-3
GO:0048382 mesendoderm development 1.631821e-3
GO:0051152 positive regulation of smooth muscle cell differentiation 1.657360e-3
GO:0035887 aortic smooth muscle cell differentiation 1.809702e-3
GO:0051494 negative regulation of cytoskeleton organization 1.812346e-3
GO:0006659 phosphatidylserine biosynthetic process 1.818593e-3
GO:0035414 negative regulation of catenin import into nucleus 1.831113e-3
GO:0051639 actin filament network formation 1.846162e-3
GO:0007092 activation of mitotic anaphase-promoting complex activity 1.846162e-3
GO:0031658 negative regulation of cyclin-dependent protein kinase activity involved in G1/S 1.846162e-3
GO:0002642 positive regulation of immunoglobulin biosynthetic process 1.890894e-3
GO:0031584 activation of phospholipase D activity 1.919332e-3
GO:0072124 regulation of glomerular mesangial cell proliferation 1.947915e-3
GO:0002537 nitric oxide production involved in inflammatory response 2.008533e-3
GO:0032370 positive regulation of lipid transport 2.061128e-3
GO:0048671 negative regulation of collateral sprouting 2.089224e-3
GO:0043087 regulation of GTPase activity 2.117972e-3
GO:0002561 basophil degranulation 2.227656e-3
GO:0002357 defense response to tumor cell 2.227656e-3
GO:0071545 inositol phosphate catabolic process 2.240834e-3
GO:0001841 neural tube formation 2.262220e-3
GO:0051898 negative regulation of protein kinase B signaling cascade 2.274689e-3
GO:0033124 regulation of GTP catabolic process 2.297836e-3
GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly 2.305902e-3
GO:0072015 glomerular visceral epithelial cell development 2.305902e-3
GO:0051301 cell division 2.376688e-3
GO:0033006 regulation of mast cell activation involved in immune response 2.461752e-3
GO:0021535 cell migration in hindbrain 2.471840e-3
GO:0043653 mitochondrial fragmentation involved in apoptosis 2.487167e-3
GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process 2.633071e-3
GO:0010875 positive regulation of cholesterol efflux 2.762696e-3
GO:0033261 regulation of S phase 2.782538e-3
GO:0046599 regulation of centriole replication 2.820586e-3
GO:0051387 negative regulation of nerve growth factor receptor signaling pathway 3.034025e-3
GO:0046488 phosphatidylinositol metabolic process 3.069504e-3
GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway 3.117217e-3
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 3.171848e-3
GO:0046755 non-lytic virus budding 3.171848e-3
GO:0006551 leucine metabolic process 3.179639e-3
GO:0002092 positive regulation of receptor internalization 3.225280e-3
GO:0032728 positive regulation of interferon-beta production 3.353132e-3
GO:0042254 ribosome biogenesis 3.376100e-3
GO:0043687 post-translational protein modification 3.523526e-3
GO:0051129 negative regulation of cellular component organization 3.749685e-3
GO:0051488 activation of anaphase-promoting complex activity 3.783785e-3
GO:0006578 betaine biosynthetic process 3.783785e-3
GO:0003197 endocardial cushion development 3.911470e-3
GO:0046855 inositol phosphate dephosphorylation 3.991549e-3
GO:0034470 ncRNA processing 4.036844e-3
GO:0017148 negative regulation of translation 4.049010e-3
GO:0016180 snRNA processing 4.120089e-3
GO:0033523 histone H2B ubiquitination 4.166035e-3
GO:2000425 regulation of apoptotic cell clearance 4.246861e-3
GO:0010948 negative regulation of cell cycle process 4.247908e-3
GO:0071529 cementum mineralization 4.289464e-3
GO:0090085 regulation of protein deubiquitination 4.289464e-3
GO:0060564 negative regulation of mitotic anaphase-promoting complex activity 4.290344e-3
GO:0006561 proline biosynthetic process 4.290344e-3
GO:0007614 short-term memory 4.617966e-3
GO:0035117 embryonic arm morphogenesis 4.670463e-3
GO:0003156 regulation of organ formation 4.682851e-3
GO:0043471 regulation of cellular carbohydrate catabolic process 4.709068e-3
GO:0006288 base-excision repair, DNA ligation 4.714893e-3
GO:0006032 chitin catabolic process 4.714893e-3
GO:0009236 cobalamin biosynthetic process 4.720211e-3
GO:0022400 regulation of rhodopsin mediated signaling pathway 4.720211e-3
GO:0045575 basophil activation 4.720211e-3
GO:0019047 provirus integration 4.720211e-3
GO:0051147 regulation of muscle cell differentiation 4.741385e-3
GO:0006488 dolichol-linked oligosaccharide biosynthetic process 4.771797e-3
GO:0045661 regulation of myoblast differentiation 5.071648e-3
GO:0010874 regulation of cholesterol efflux 5.086449e-3
GO:0032776 DNA methylation on cytosine 5.149903e-3
GO:0043966 histone H3 acetylation 5.265681e-3
GO:0071894 histone H2B conserved C-terminal lysine ubiquitination 5.275424e-3
GO:0050861 positive regulation of B cell receptor signaling pathway 5.275424e-3
GO:0043304 regulation of mast cell degranulation 5.423789e-3
GO:0048368 lateral mesoderm development 5.432376e-3
GO:0002318 myeloid progenitor cell differentiation 5.501464e-3
GO:0030046 parallel actin filament bundle assembly 5.506675e-3
GO:0015705 iodide transport 5.506675e-3
GO:0034661 ncRNA catabolic process 5.546901e-3
GO:0014020 primary neural tube formation 5.624161e-3
GO:0001947 heart looping 5.644070e-3
GO:0045347 negative regulation of MHC class II biosynthetic process 5.676743e-3
GO:0016925 protein sumoylation 5.778012e-3
GO:0045819 positive regulation of glycogen catabolic process 5.780129e-3
GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process 5.881998e-3
GO:0046434 organophosphate catabolic process 5.884415e-3
GO:0034261 negative regulation of Ras GTPase activity 6.199279e-3
GO:0032376 positive regulation of cholesterol transport 6.228449e-3
GO:0050850 positive regulation of calcium-mediated signaling 6.318746e-3
GO:0052556 positive regulation by symbiont of host immune response 6.407448e-3
GO:0003285 septum secundum development 6.407448e-3
GO:0052509 positive regulation by symbiont of host defense response 6.407448e-3
GO:0030902 hindbrain development 6.431133e-3
GO:0045943 positive regulation of transcription from RNA polymerase I promoter 6.448480e-3
GO:0021783 preganglionic parasympathetic nervous system development 6.718224e-3
GO:0060179 male mating behavior 6.893674e-3
GO:0032226 positive regulation of synaptic transmission, dopaminergic 6.893674e-3
GO:0006097 glyoxylate cycle 6.893674e-3
GO:0001560 regulation of cell growth by extracellular stimulus 6.974225e-3
GO:0043482 cellular pigment accumulation 7.025789e-3
GO:0022037 metencephalon development 7.158845e-3
GO:0042274 ribosomal small subunit biogenesis 7.346811e-3
GO:0052033 pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity 7.379224e-3
GO:0010587 miRNA catabolic process 7.379224e-3
GO:0051541 elastin metabolic process 7.410599e-3
GO:2000297 negative regulation of synapse maturation 7.448763e-3
GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway 7.448763e-3
GO:0042048 olfactory behavior 7.448763e-3
GO:0009169 purine ribonucleoside monophosphate catabolic process 7.448763e-3
GO:0048532 anatomical structure arrangement 7.565326e-3
GO:0001759 organ induction 7.565326e-3
GO:0070244 negative regulation of thymocyte apoptosis 7.609832e-3
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 7.610929e-3
GO:0072301 regulation of metanephric glomerular mesangial cell proliferation 7.885005e-3
GO:0032264 IMP salvage 8.187269e-3
GO:0046038 GMP catabolic process 8.187269e-3
GO:0023035 CD40 signaling pathway 8.187269e-3
GO:0006178 guanine salvage 8.187269e-3
GO:0032263 GMP salvage 8.187269e-3
GO:0043576 regulation of respiratory gaseous exchange 8.232761e-3
GO:0045168 cell-cell signaling involved in cell fate commitment 8.462527e-3
GO:0060155 platelet dense granule organization 8.471328e-3
GO:0060928 atrioventricular node cell development 8.576781e-3
GO:0060929 atrioventricular node cell fate commitment 8.576781e-3
GO:0006844 acyl carnitine transport 8.576781e-3
GO:0003168 cardiac Purkinje fiber cell differentiation 8.576781e-3
GO:0002462 tolerance induction to nonself antigen 8.576781e-3
GO:0003342 proepicardium development 8.576781e-3
GO:0061136 regulation of proteasomal protein catabolic process 8.717617e-3
GO:0048378 regulation of lateral mesodermal cell fate specification 8.723083e-3
GO:0000422 mitochondrion degradation 8.723083e-3
GO:0060159 regulation of dopamine receptor signaling pathway 8.778265e-3
GO:0043388 positive regulation of DNA binding 9.071650e-3
GO:0001838 embryonic epithelial tube formation 9.094023e-3
GO:0000085 G2 phase of mitotic cell cycle 9.611307e-3
GO:0072198 mesenchymal cell proliferation involved in ureter development 9.622464e-3
GO:0072192 ureter epithelial cell differentiation 9.622464e-3
GO:0072200 negative regulation of mesenchymal cell proliferation involved in ureter development 9.622464e-3
GO:0072138 mesenchymal cell proliferation involved in ureteric bud development 9.622464e-3
GO:0072101 specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway 9.622464e-3
GO:2000007 negative regulation of metanephric comma-shaped body morphogenesis 9.622464e-3
GO:0072097 negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway 9.622464e-3
GO:2000137 negative regulation of cell proliferation involved in heart morphogenesis 9.622464e-3
GO:2000005 negative regulation of metanephric S-shaped body morphogenesis 9.622464e-3
GO:0090194 negative regulation of glomerulus development 9.622464e-3
GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis 9.622464e-3
GO:0007500 mesodermal cell fate determination 9.622464e-3
GO:0055020 positive regulation of cardiac muscle fiber development 9.622464e-3
GO:0071893 BMP signaling pathway involved in nephric duct formation 9.622464e-3
GO:0048392 intermediate mesodermal cell differentiation 9.622464e-3
GO:0006481 C-terminal protein methylation 9.622464e-3
GO:0060502 epithelial cell proliferation involved in lung morphogenesis 9.622464e-3
GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process 9.622464e-3
GO:0061155 pulmonary artery endothelial tube morphogenesis 9.622464e-3
GO:0061151 BMP signaling pathway involved in renal system segmentation 9.622464e-3
GO:0061149 BMP signaling pathway involved in ureter morphogenesis 9.622464e-3
GO:0060503 bud dilation involved in lung branching 9.622464e-3
GO:0051153 regulation of striated muscle cell differentiation 9.661225e-3
GO:0031128 developmental induction 9.764634e-3
GO:0035928 rRNA import into mitochondrion 9.848843e-3
GO:0019388 galactose catabolic process 9.848843e-3
GO:0009268 response to pH 9.863759e-3
GO:0045454 cell redox homeostasis 1.000354e-2
GO:0060396 growth hormone receptor signaling pathway 1.003247e-2
GO:0032785 negative regulation of transcription elongation, DNA-dependent 1.008302e-2
GO:0033205 cell cycle cytokinesis 1.008448e-2
GO:0007252 I-kappaB phosphorylation 1.017909e-2
GO:0001675 acrosome assembly 1.017909e-2
GO:0032025 response to cobalt ion 1.030857e-2
GO:0003350 pulmonary myocardium development 1.030857e-2
GO:0060449 bud elongation involved in lung branching 1.038408e-2
GO:0033363 secretory granule organization 1.073903e-2
GO:0010741 negative regulation of intracellular protein kinase cascade 1.110521e-2
GO:0046856 phosphatidylinositol dephosphorylation 1.112479e-2
GO:0072215 regulation of metanephros development 1.123407e-2
GO:0000266 mitochondrial fission 1.141802e-2
GO:0002224 toll-like receptor signaling pathway 1.141802e-2
GO:0016073 snRNA metabolic process 1.144346e-2
GO:0006941 striated muscle contraction 1.159527e-2
GO:0016358 dendrite development 1.163538e-2
GO:0048486 parasympathetic nervous system development 1.165010e-2
GO:0002221 pattern recognition receptor signaling pathway 1.181578e-2
GO:0007354 zygotic determination of anterior/posterior axis, embryo 1.204225e-2
GO:0071711 basement membrane organization 1.204225e-2
GO:0090238 positive regulation of arachidonic acid secretion 1.204898e-2
GO:0045356 positive regulation of interferon-alpha biosynthetic process 1.204898e-2
GO:0018095 protein polyglutamylation 1.204898e-2
GO:0002138 retinoic acid biosynthetic process 1.204898e-2
GO:0071378 cellular response to growth hormone stimulus 1.205930e-2
GO:0072199 regulation of mesenchymal cell proliferation involved in ureter development 1.210318e-2
GO:0021602 cranial nerve morphogenesis 1.214799e-2
GO:0061113 pancreas morphogenesis 1.217969e-2
GO:0033148 positive regulation of estrogen receptor signaling pathway 1.217969e-2
GO:0034660 ncRNA metabolic process 1.218415e-2
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 1.248513e-2
GO:0072175 epithelial tube formation 1.262439e-2
GO:0046129 purine ribonucleoside biosynthetic process 1.267591e-2
GO:0060427 lung connective tissue development 1.276662e-2
GO:2000119 negative regulation of sodium-dependent phosphate transport 1.298320e-2
GO:0031619 homologous chromosome orientation involved in meiotic metaphase I plate congression 1.298320e-2
GO:0034394 protein localization at cell surface 1.299924e-2
GO:2000171 negative regulation of dendrite development 1.319090e-2
GO:0090340 positive regulation of secretion of lysosomal enzymes 1.343029e-2
GO:0090187 positive regulation of pancreatic juice secretion 1.343029e-2
GO:0006393 termination of mitochondrial transcription 1.343029e-2
GO:0060847 endothelial cell fate specification 1.343029e-2
GO:0090108 positive regulation of high-density lipoprotein particle assembly 1.343029e-2
GO:2000018 regulation of male gonad development 1.354484e-2
GO:0031331 positive regulation of cellular catabolic process 1.384928e-2
GO:0070734 histone H3-K27 methylation 1.391012e-2
GO:0061156 pulmonary artery morphogenesis 1.391012e-2
GO:0030836 positive regulation of actin filament depolymerization 1.391012e-2
GO:0051001 negative regulation of nitric-oxide synthase activity 1.398479e-2
GO:0042417 dopamine metabolic process 1.400340e-2
GO:0071882 activation of phospholipase C activity by adrenergic receptor signaling pathway 1.403234e-2
GO:0071881 inhibition of adenylate cyclase activity by adrenergic receptor signaling pathway 1.403234e-2
GO:0016331 morphogenesis of embryonic epithelium 1.415577e-2
GO:0006346 methylation-dependent chromatin silencing 1.420388e-2
GO:0002248 connective tissue replacement involved in inflammatory response wound healing 1.420388e-2
GO:0016082 synaptic vesicle priming 1.420842e-2
GO:0006546 glycine catabolic process 1.420842e-2
GO:0042773 ATP synthesis coupled electron transport 1.425077e-2
GO:0060390 regulation of SMAD protein import into nucleus 1.455933e-2
GO:0060729 intestinal epithelial structure maintenance 1.479598e-2
GO:0002282 microglial cell activation involved in immune response 1.479598e-2
GO:0009894 regulation of catabolic process 1.503698e-2
GO:0048285 organelle fission 1.510390e-2
GO:0016072 rRNA metabolic process 1.532057e-2
GO:0010639 negative regulation of organelle organization 1.536475e-2
GO:0060754 positive regulation of mast cell chemotaxis 1.555061e-2
GO:0001661 conditioned taste aversion 1.555061e-2
GO:0014819 regulation of skeletal muscle contraction 1.558343e-2
GO:0071354 cellular response to interleukin-6 1.583549e-2
GO:0060033 anatomical structure regression 1.595945e-2
GO:0090263 positive regulation of canonical Wnt receptor signaling pathway 1.596079e-2
GO:0032364 oxygen homeostasis 1.605003e-2
GO:0021756 striatum development 1.606698e-2
GO:0046847 filopodium assembly 1.611192e-2
GO:0043586 tongue development 1.617860e-2
GO:0045768 positive regulation of anti-apoptosis 1.622998e-2
GO:0016539 intein-mediated protein splicing 1.625685e-2
GO:0045654 positive regulation of megakaryocyte differentiation 1.653269e-2
GO:0006166 purine ribonucleoside salvage 1.653269e-2
GO:0006072 glycerol-3-phosphate metabolic process 1.665566e-2
GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching 1.666108e-2
GO:0021915 neural tube development 1.670771e-2
GO:0050918 positive chemotaxis 1.681143e-2
GO:0000724 double-strand break repair via homologous recombination 1.681143e-2
GO:0070831 basement membrane assembly 1.698072e-2
GO:0045226 extracellular polysaccharide biosynthetic process 1.698072e-2
GO:0046500 S-adenosylmethionine metabolic process 1.699811e-2
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 1.699873e-2
GO:0014743 regulation of muscle hypertrophy 1.707384e-2
GO:0003283 atrial septum development 1.707384e-2
GO:0045123 cellular extravasation 1.709617e-2
GO:0035990 tendon cell differentiation 1.722454e-2
GO:0021530 spinal cord oligodendrocyte cell fate specification 1.722454e-2
GO:0045862 positive regulation of proteolysis 1.725317e-2
GO:0051297 centrosome organization 1.747684e-2
GO:0060828 regulation of canonical Wnt receptor signaling pathway 1.755879e-2
GO:0043409 negative regulation of MAPKKK cascade 1.762763e-2
GO:0006661 phosphatidylinositol biosynthetic process 1.809097e-2
GO:0072166 posterior mesonephric tubule development 1.817391e-2
GO:0019344 cysteine biosynthetic process 1.817391e-2
GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development 1.841063e-2
GO:0050765 negative regulation of phagocytosis 1.896164e-2
GO:2000020 positive regulation of male gonad development 1.904222e-2
GO:0033373 maintenance of protease location in mast cell secretory granule 1.916135e-2
GO:0033382 maintenance of granzyme B location in T cell secretory granule 1.916135e-2
GO:0032225 regulation of synaptic transmission, dopaminergic 1.937955e-2
GO:0032486 Rap protein signal transduction 1.940419e-2
GO:0052572 response to host immune response 1.950360e-2
GO:0060413 atrial septum morphogenesis 2.020291e-2
GO:0030834 regulation of actin filament depolymerization 2.032841e-2
GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development 2.037134e-2
GO:0007049 cell cycle 2.047905e-2
GO:0001843 neural tube closure 2.087273e-2
GO:0021559 trigeminal nerve development 2.109454e-2
GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway 2.126749e-2
GO:0030327 prenylated protein catabolic process 2.126749e-2
GO:0008295 spermidine biosynthetic process 2.126749e-2
GO:0014063 negative regulation of serotonin secretion 2.126749e-2
GO:0030035 microspike assembly 2.128316e-2
GO:0045637 regulation of myeloid cell differentiation 2.140424e-2
GO:0030433 ER-associated protein catabolic process 2.157825e-2
GO:0048742 regulation of skeletal muscle fiber development 2.166303e-2
GO:0010811 positive regulation of cell-substrate adhesion 2.168476e-2
GO:0071843 cellular component biogenesis at cellular level 2.168854e-2
GO:0032481 positive regulation of type I interferon production 2.170444e-2
GO:0032677 regulation of interleukin-8 production 2.172550e-2
GO:2000104 negative regulation of DNA-dependent DNA replication 2.181828e-2
GO:0010832 negative regulation of myotube differentiation 2.181828e-2
GO:0060351 cartilage development involved in endochondral bone morphogenesis 2.185664e-2
GO:0031055 chromatin remodeling at centromere 2.206946e-2
GO:0003151 outflow tract morphogenesis 2.214765e-2
GO:0006412 translation 2.216217e-2
GO:0043103 hypoxanthine salvage 2.224515e-2
GO:0060540 diaphragm morphogenesis 2.224515e-2
GO:0060464 lung lobe formation 2.224515e-2
GO:0032261 purine nucleotide salvage 2.224515e-2
GO:0018065 protein-cofactor linkage 2.224515e-2
GO:0006168 adenine salvage 2.224515e-2
GO:0031648 protein destabilization 2.243352e-2
GO:0051584 regulation of dopamine uptake 2.247382e-2
GO:0043101 purine-containing compound salvage 2.247382e-2
GO:0010830 regulation of myotube differentiation 2.266381e-2
GO:0035993 deltoid tuberosity development 2.278589e-2
GO:0016075 rRNA catabolic process 2.278589e-2
GO:0010572 positive regulation of platelet activation 2.278589e-2
GO:0060562 epithelial tube morphogenesis 2.300665e-2
GO:0007019 microtubule depolymerization 2.308518e-2
GO:0003278 apoptosis involved in heart morphogenesis 2.308518e-2
GO:0010575 positive regulation vascular endothelial growth factor production 2.314243e-2
GO:0048588 developmental cell growth 2.316251e-2
GO:0061004 pattern specification involved in kidney development 2.340536e-2
GO:0051891 positive regulation of cardioblast differentiation 2.360157e-2
GO:0043587 tongue morphogenesis 2.360157e-2
GO:0060691 epithelial cell maturation involved in salivary gland development 2.373874e-2
GO:0071284 cellular response to lead ion 2.373874e-2
GO:0060096 serotonin secretion, neurotransmission 2.373874e-2
GO:0043128 positive regulation of 1-phosphatidylinositol 4-kinase activity 2.373874e-2
GO:0018160 peptidyl-pyrromethane cofactor linkage 2.373874e-2
GO:0006571 tyrosine biosynthetic process 2.373874e-2
GO:0021545 cranial nerve development 2.376976e-2
GO:0018027 peptidyl-lysine dimethylation 2.381592e-2
GO:0045005 maintenance of fidelity involved in DNA-dependent DNA replication 2.381592e-2
GO:0030853 negative regulation of granulocyte differentiation 2.411539e-2
GO:0003382 epithelial cell morphogenesis 2.426062e-2
GO:0060986 endocrine hormone secretion 2.435292e-2
GO:0019695 choline metabolic process 2.466306e-2
GO:0009083 branched chain family amino acid catabolic process 2.466306e-2
GO:2001054 negative regulation of mesenchymal cell apoptosis 2.492607e-2
GO:0031054 pre-miRNA processing 2.504679e-2
GO:0046498 S-adenosylhomocysteine metabolic process 2.504679e-2
GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly 2.507001e-2
GO:0000725 recombinational repair 2.517961e-2
GO:0071526 semaphorin-plexin signaling pathway 2.535516e-2
GO:0043088 regulation of Cdc42 GTPase activity 2.563424e-2
GO:0043486 histone exchange 2.588374e-2
GO:0008595 anterior/posterior axis specification, embryo 2.595052e-2
GO:0035050 embryonic heart tube development 2.629498e-2
GO:0035162 embryonic hemopoiesis 2.649128e-2
GO:0072278 metanephric comma-shaped body morphogenesis 2.651825e-2
GO:0072284 metanephric S-shaped body morphogenesis 2.651825e-2
GO:0055099 response to high density lipoprotein particle stimulus 2.651825e-2
GO:0035022 positive regulation of Rac protein signal transduction 2.658495e-2
GO:0006596 polyamine biosynthetic process 2.658495e-2
GO:0070542 response to fatty acid 2.663489e-2
GO:0071223 cellular response to lipoteichoic acid 2.675717e-2
GO:0070925 organelle assembly 2.675967e-2
GO:0006556 S-adenosylmethionine biosynthetic process 2.687455e-2
GO:0042255 ribosome assembly 2.740572e-2
GO:0000188 inactivation of MAPK activity 2.746749e-2
GO:0010810 regulation of cell-substrate adhesion 2.781294e-2
GO:0042659 regulation of cell fate specification 2.814109e-2
GO:0021516 dorsal spinal cord development 2.814109e-2
GO:0046487 glyoxylate metabolic process 2.816371e-2
GO:0042245 RNA repair 2.816371e-2
GO:0008306 associative learning 2.816491e-2
GO:0021549 cerebellum development 2.837237e-2
GO:0010611 regulation of cardiac muscle hypertrophy 2.853217e-2
GO:0060606 tube closure 2.899657e-2
GO:2000602 regulation of interphase of mitotic cell cycle 2.931398e-2
GO:0045109 intermediate filament organization 2.951452e-2
GO:0045956 positive regulation of calcium ion-dependent exocytosis 2.962140e-2
GO:0045815 positive regulation of gene expression, epigenetic 2.962140e-2
GO:0009948 anterior/posterior axis specification 2.970388e-2
GO:0031442 positive regulation of mRNA 3'-end processing 2.978291e-2
GO:0048387 negative regulation of retinoic acid receptor signaling pathway 2.990207e-2