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Novel motif:119

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name:motif119_TCAAAANCG

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0006281 DNA repair 1.152724e-12
GO:0071044 histone mRNA catabolic process 1.162461e-11
GO:0007094 mitotic cell cycle spindle assembly checkpoint 3.474359e-11
GO:0015742 alpha-ketoglutarate transport 3.763384e-11
GO:0071173 spindle assembly checkpoint 5.736781e-11
GO:0071174 mitotic cell cycle spindle checkpoint 6.334597e-11
GO:0045841 negative regulation of mitotic metaphase/anaphase transition 1.254375e-10
GO:0031577 spindle checkpoint 1.380892e-10
GO:0006289 nucleotide-excision repair 1.786219e-10
GO:0000296 spermine transport 1.403719e-9
GO:0022402 cell cycle process 4.197584e-9
GO:0046940 nucleoside monophosphate phosphorylation 4.198050e-9
GO:0030071 regulation of mitotic metaphase/anaphase transition 5.407658e-9
GO:0090399 replicative senescence 5.746870e-9
GO:0006259 DNA metabolic process 8.231544e-9
GO:0010754 negative regulation of cGMP-mediated signaling 8.419814e-9
GO:0043652 engulfment of apoptotic cell 8.419814e-9
GO:0002605 negative regulation of dendritic cell antigen processing and presentation 8.419814e-9
GO:0010751 negative regulation of nitric oxide mediated signal transduction 8.419814e-9
GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 8.419814e-9
GO:0000278 mitotic cell cycle 1.254074e-8
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway 1.464073e-8
GO:0010994 free ubiquitin chain polymerization 1.965093e-8
GO:0060574 intestinal epithelial cell maturation 1.965093e-8
GO:0022403 cell cycle phase 3.464126e-8
GO:0006303 double-strand break repair via nonhomologous end joining 3.698434e-8
GO:0051329 interphase of mitotic cell cycle 3.763519e-8
GO:0045839 negative regulation of mitosis 4.069695e-8
GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport 6.004789e-8
GO:0051325 interphase 6.506433e-8
GO:0032026 response to magnesium ion 8.199417e-8
GO:0040040 thermosensory behavior 8.324543e-8
GO:0032369 negative regulation of lipid transport 1.232340e-7
GO:0000075 cell cycle checkpoint 1.370747e-7
GO:0060764 cell-cell signaling involved in mammary gland development 1.635937e-7
GO:0006975 DNA damage induced protein phosphorylation 1.676504e-7
GO:0042535 positive regulation of tumor necrosis factor biosynthetic process 2.705898e-7
GO:0032891 negative regulation of organic acid transport 2.861661e-7
GO:0051897 positive regulation of protein kinase B signaling cascade 3.357321e-7
GO:0010755 regulation of plasminogen activation 3.402193e-7
GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition 3.846437e-7
GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation 3.846437e-7
GO:0032074 negative regulation of nuclease activity 3.999737e-7
GO:0019087 transformation of host cell by virus 4.425740e-7
GO:0002331 pre-B cell allelic exclusion 4.737477e-7
GO:0045786 negative regulation of cell cycle 4.867086e-7
GO:0006283 transcription-coupled nucleotide-excision repair 5.266035e-7
GO:0031123 RNA 3'-end processing 5.545838e-7
GO:0008049 male courtship behavior 6.153789e-7
GO:0006370 mRNA capping 6.172529e-7
GO:0006105 succinate metabolic process 6.788070e-7
GO:2000786 positive regulation of autophagic vacuole assembly 7.898829e-7
GO:0010591 regulation of lamellipodium assembly 9.657889e-7
GO:0043032 positive regulation of macrophage activation 9.766393e-7
GO:0043537 negative regulation of blood vessel endothelial cell migration 1.205986e-6
GO:0006333 chromatin assembly or disassembly 1.238268e-6
GO:0001953 negative regulation of cell-matrix adhesion 1.315346e-6
GO:0008334 histone mRNA metabolic process 1.324539e-6
GO:0001937 negative regulation of endothelial cell proliferation 1.376616e-6
GO:0010746 regulation of plasma membrane long-chain fatty acid transport 1.379589e-6
GO:0010458 exit from mitosis 1.544740e-6
GO:0006352 transcription initiation, DNA-dependent 1.664770e-6
GO:0042276 error-prone translesion synthesis 1.668503e-6
GO:0006367 transcription initiation from RNA polymerase II promoter 1.957254e-6
GO:0010812 negative regulation of cell-substrate adhesion 2.033759e-6
GO:0071156 regulation of cell cycle arrest 2.144280e-6
GO:0009452 RNA capping 2.415838e-6
GO:0016032 viral reproduction 2.737611e-6
GO:0034621 cellular macromolecular complex subunit organization 3.191917e-6
GO:0007093 mitotic cell cycle checkpoint 3.311577e-6
GO:2000119 negative regulation of sodium-dependent phosphate transport 3.326925e-6
GO:0010763 positive regulation of fibroblast migration 4.448622e-6
GO:0051444 negative regulation of ubiquitin-protein ligase activity 4.602545e-6
GO:0051208 sequestering of calcium ion 4.861809e-6
GO:0006413 translational initiation 5.810551e-6
GO:0051438 regulation of ubiquitin-protein ligase activity 6.156589e-6
GO:0044088 regulation of vacuole organization 6.305271e-6
GO:0090398 cellular senescence 6.306163e-6
GO:0035404 histone-serine phosphorylation 7.212417e-6
GO:0090281 negative regulation of calcium ion import 7.495067e-6
GO:0071584 negative regulation of zinc ion import 7.495067e-6
GO:0043030 regulation of macrophage activation 7.721590e-6
GO:0031081 nuclear pore distribution 7.846999e-6
GO:0060435 bronchiole development 8.135335e-6
GO:0042534 regulation of tumor necrosis factor biosynthetic process 8.545554e-6
GO:0071460 cellular response to cell-matrix adhesion 8.583551e-6
GO:0071585 detoxification of cadmium ion 1.000721e-5
GO:0042977 activation of JAK2 kinase activity 1.088787e-5
GO:0032914 positive regulation of transforming growth factor beta1 production 1.201916e-5
GO:0000082 G1/S transition of mitotic cell cycle 1.253640e-5
GO:0002069 columnar/cuboidal epithelial cell maturation 1.418729e-5
GO:0031103 axon regeneration 1.470362e-5
GO:0051896 regulation of protein kinase B signaling cascade 1.493087e-5
GO:0048168 regulation of neuronal synaptic plasticity 1.606809e-5
GO:0002577 regulation of antigen processing and presentation 1.631381e-5
GO:0006354 transcription elongation, DNA-dependent 1.685750e-5
GO:0051895 negative regulation of focal adhesion assembly 1.741953e-5
GO:0042255 ribosome assembly 1.925855e-5
GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 2.020600e-5
GO:0007049 cell cycle 2.070298e-5
GO:0006353 transcription termination, DNA-dependent 2.096556e-5
GO:0051340 regulation of ligase activity 2.108748e-5
GO:0031497 chromatin assembly 2.372152e-5
GO:0051168 nuclear export 2.390803e-5
GO:0010757 negative regulation of plasminogen activation 2.398071e-5
GO:0034766 negative regulation of ion transmembrane transport 2.491330e-5
GO:0051918 negative regulation of fibrinolysis 2.500248e-5
GO:0006399 tRNA metabolic process 2.504154e-5
GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway 2.607509e-5
GO:0046165 alcohol biosynthetic process 2.657944e-5
GO:0071824 protein-DNA complex subunit organization 2.766995e-5
GO:0000726 non-recombinational repair 2.780699e-5
GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 2.824992e-5
GO:0050908 detection of light stimulus involved in visual perception 2.834176e-5
GO:0090304 nucleic acid metabolic process 3.053836e-5
GO:0015734 taurine transport 3.092613e-5
GO:0031102 neuron projection regeneration 3.244889e-5
GO:0006302 double-strand break repair 3.385237e-5
GO:0051443 positive regulation of ubiquitin-protein ligase activity 3.564553e-5
GO:0006493 protein O-linked glycosylation 3.617999e-5
GO:0046449 creatinine metabolic process 3.816166e-5
GO:0006664 glycolipid metabolic process 4.071309e-5
GO:0046929 negative regulation of neurotransmitter secretion 4.190693e-5
GO:0016241 regulation of macroautophagy 4.190693e-5
GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry 4.378479e-5
GO:0019377 glycolipid catabolic process 5.237222e-5
GO:0046467 membrane lipid biosynthetic process 5.305766e-5
GO:0007163 establishment or maintenance of cell polarity 5.615977e-5
GO:0070535 histone H2A K63-linked ubiquitination 6.041640e-5
GO:0016476 regulation of embryonic cell shape 6.117765e-5
GO:0006349 regulation of gene expression by genetic imprinting 6.268519e-5
GO:0071423 malate transmembrane transport 6.527006e-5
GO:0015709 thiosulfate transport 6.527006e-5
GO:0006756 AMP phosphorylation 6.527006e-5
GO:0010756 positive regulation of plasminogen activation 6.675715e-5
GO:0045684 positive regulation of epidermis development 6.714548e-5
GO:0034763 negative regulation of transmembrane transport 6.837775e-5
GO:0000959 mitochondrial RNA metabolic process 6.945213e-5
GO:0006974 response to DNA damage stimulus 7.000741e-5
GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator 7.400543e-5
GO:0007614 short-term memory 7.400543e-5
GO:0051917 regulation of fibrinolysis 7.471636e-5
GO:0042416 dopamine biosynthetic process 7.653220e-5
GO:0000723 telomere maintenance 8.218627e-5
GO:0000255 allantoin metabolic process 8.838430e-5
GO:0034728 nucleosome organization 8.842969e-5
GO:0003341 cilium movement 8.954789e-5
GO:0043525 positive regulation of neuron apoptosis 9.280641e-5
GO:0016056 rhodopsin mediated signaling pathway 9.398452e-5
GO:0043570 maintenance of DNA repeat elements 9.433843e-5
GO:0006427 histidyl-tRNA aminoacylation 9.733990e-5
GO:0046512 sphingosine biosynthetic process 1.036256e-4
GO:0072659 protein localization in plasma membrane 1.041781e-4
GO:0019530 taurine metabolic process 1.068911e-4
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 1.086719e-4
GO:0006368 transcription elongation from RNA polymerase II promoter 1.152499e-4
GO:0002502 peptide antigen assembly with MHC class I protein complex 1.166211e-4
GO:0006405 RNA export from nucleus 1.167656e-4
GO:0045606 positive regulation of epidermal cell differentiation 1.196601e-4
GO:0002604 regulation of dendritic cell antigen processing and presentation 1.212911e-4
GO:0032695 negative regulation of interleukin-12 production 1.225050e-4
GO:0006310 DNA recombination 1.250812e-4
GO:0035088 establishment or maintenance of apical/basal cell polarity 1.264722e-4
GO:0006362 transcription elongation from RNA polymerase I promoter 1.269691e-4
GO:0051351 positive regulation of ligase activity 1.277463e-4
GO:0032200 telomere organization 1.280920e-4
GO:0060052 neurofilament cytoskeleton organization 1.289640e-4
GO:0042159 lipoprotein catabolic process 1.293594e-4
GO:0045727 positive regulation of translation 1.338897e-4
GO:0000398 nuclear mRNA splicing, via spliceosome 1.339676e-4
GO:0071404 cellular response to low-density lipoprotein particle stimulus 1.373587e-4
GO:0044260 cellular macromolecule metabolic process 1.378479e-4
GO:0010758 regulation of macrophage chemotaxis 1.379312e-4
GO:0022601 menstrual cycle phase 1.439221e-4
GO:0060179 male mating behavior 1.466235e-4
GO:0060480 lung goblet cell differentiation 1.466235e-4
GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 1.528011e-4
GO:0007009 plasma membrane organization 1.541491e-4
GO:0031507 heterochromatin formation 1.589718e-4
GO:0051320 S phase 1.599711e-4
GO:0006406 mRNA export from nucleus 1.626572e-4
GO:0071675 regulation of mononuclear cell migration 1.631364e-4
GO:0010759 positive regulation of macrophage chemotaxis 1.654427e-4
GO:0070979 protein K11-linked ubiquitination 1.662709e-4
GO:0032805 positive regulation of low-density lipoprotein particle receptor catabolic process 1.745263e-4
GO:0003016 respiratory system process 1.779070e-4
GO:0043277 apoptotic cell clearance 1.807878e-4
GO:0055098 response to low-density lipoprotein particle stimulus 1.815873e-4
GO:0006369 termination of RNA polymerase II transcription 1.818676e-4
GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 1.889464e-4
GO:0031959 mineralocorticoid receptor signaling pathway 2.064496e-4
GO:0006412 translation 2.076111e-4
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity 2.171127e-4
GO:0006401 RNA catabolic process 2.203600e-4
GO:0006107 oxaloacetate metabolic process 2.279479e-4
GO:0006610 ribosomal protein import into nucleus 2.317059e-4
GO:0032057 negative regulation of translational initiation in response to stress 2.480570e-4
GO:0010596 negative regulation of endothelial cell migration 2.500508e-4
GO:0030194 positive regulation of blood coagulation 2.563046e-4
GO:0002316 follicular B cell differentiation 2.651872e-4
GO:0006549 isoleucine metabolic process 2.651872e-4
GO:0035067 negative regulation of histone acetylation 2.660366e-4
GO:0070682 proteasome regulatory particle assembly 2.742683e-4
GO:0007113 endomitotic cell cycle 2.763257e-4
GO:0006600 creatine metabolic process 2.846669e-4
GO:0009225 nucleotide-sugar metabolic process 2.851793e-4
GO:0071402 cellular response to lipoprotein particle stimulus 3.046351e-4
GO:0031124 mRNA 3'-end processing 3.054003e-4
GO:0030538 embryonic genitalia morphogenesis 3.102587e-4
GO:0016071 mRNA metabolic process 3.126124e-4
GO:0006103 2-oxoglutarate metabolic process 3.179614e-4
GO:0006396 RNA processing 3.515537e-4
GO:0033693 neurofilament bundle assembly 3.525945e-4
GO:0034622 cellular macromolecular complex assembly 3.579856e-4
GO:0042976 activation of Janus kinase activity 3.612460e-4
GO:0007050 cell cycle arrest 3.636205e-4
GO:0071514 genetic imprinting 3.763112e-4
GO:0006390 transcription from mitochondrial promoter 3.810773e-4
GO:0032908 regulation of transforming growth factor beta1 production 3.865084e-4
GO:0045647 negative regulation of erythrocyte differentiation 3.868203e-4
GO:0000375 RNA splicing, via transesterification reactions 4.015677e-4
GO:0033119 negative regulation of RNA splicing 4.031128e-4
GO:0071622 regulation of granulocyte chemotaxis 4.135340e-4
GO:0000086 G2/M transition of mitotic cell cycle 4.160957e-4
GO:0051589 negative regulation of neurotransmitter transport 4.309025e-4
GO:0007214 gamma-aminobutyric acid signaling pathway 4.444155e-4
GO:0019303 D-ribose catabolic process 4.533831e-4
GO:0035083 cilium axoneme assembly 4.667493e-4
GO:0030148 sphingolipid biosynthetic process 4.834095e-4
GO:0019276 UDP-N-acetylgalactosamine metabolic process 4.922968e-4
GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process 4.937145e-4
GO:0015780 nucleotide-sugar transport 5.011760e-4
GO:0070613 regulation of protein processing 5.028515e-4
GO:0017183 peptidyl-diphthamide biosynthetic process from peptidyl-histidine 5.037650e-4
GO:0030838 positive regulation of actin filament polymerization 5.107553e-4
GO:0042423 catecholamine biosynthetic process 5.204132e-4
GO:0000279 M phase 5.219944e-4
GO:0000084 S phase of mitotic cell cycle 5.426599e-4
GO:0032055 negative regulation of translation in response to stress 5.779966e-4
GO:0051488 activation of anaphase-promoting complex activity 5.804968e-4
GO:0000209 protein polyubiquitination 5.812937e-4
GO:0065002 intracellular protein transmembrane transport 5.883808e-4
GO:0042780 tRNA 3'-end processing 6.101919e-4
GO:0043526 neuroprotection 6.208094e-4
GO:0060058 positive regulation of apoptosis involved in mammary gland involution 6.336750e-4
GO:0035722 interleukin-12-mediated signaling pathway 6.336750e-4
GO:0003009 skeletal muscle contraction 6.629595e-4
GO:0006101 citrate metabolic process 6.675428e-4
GO:0051028 mRNA transport 6.733370e-4
GO:0007088 regulation of mitosis 6.759383e-4
GO:0006097 glyoxylate cycle 6.863517e-4
GO:0046544 development of secondary male sexual characteristics 6.976966e-4
GO:0043631 RNA polyadenylation 7.059998e-4
GO:0014012 peripheral nervous system axon regeneration 7.244233e-4
GO:0030704 vitelline membrane formation 7.340737e-4
GO:0007126 meiosis 7.412811e-4
GO:0010957 negative regulation of vitamin D biosynthetic process 7.420915e-4
GO:0019047 provirus integration 7.473780e-4
GO:0045083 negative regulation of interleukin-12 biosynthetic process 7.872402e-4
GO:0021530 spinal cord oligodendrocyte cell fate specification 7.872402e-4
GO:0022415 viral reproductive process 7.942287e-4
GO:0007442 hindgut morphogenesis 8.005063e-4
GO:0006363 termination of RNA polymerase I transcription 8.056760e-4
GO:0042104 positive regulation of activated T cell proliferation 8.149796e-4
GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning 8.399671e-4
GO:0019083 viral transcription 8.433432e-4
GO:0007098 centrosome cycle 8.465066e-4
GO:0030719 P granule organization 8.532267e-4
GO:0090130 tissue migration 8.681762e-4
GO:0070231 T cell apoptosis 9.006848e-4
GO:0050680 negative regulation of epithelial cell proliferation 9.249603e-4
GO:0016339 calcium-dependent cell-cell adhesion 9.488768e-4
GO:0051293 establishment of spindle localization 9.596512e-4
GO:0046939 nucleotide phosphorylation 9.805689e-4
GO:0050820 positive regulation of coagulation 9.815071e-4
GO:2000330 positive regulation of T-helper 17 cell lineage commitment 9.847507e-4
GO:2000318 positive regulation of T-helper 17 type immune response 9.847507e-4
GO:0010955 negative regulation of protein processing 1.004333e-3
GO:0046511 sphinganine biosynthetic process 1.022506e-3
GO:0000226 microtubule cytoskeleton organization 1.029535e-3
GO:0006643 membrane lipid metabolic process 1.036365e-3
GO:0031397 negative regulation of protein ubiquitination 1.037094e-3
GO:0065004 protein-DNA complex assembly 1.040760e-3
GO:0010631 epithelial cell migration 1.065777e-3
GO:0048524 positive regulation of viral reproduction 1.087096e-3
GO:0009226 nucleotide-sugar biosynthetic process 1.089068e-3
GO:0018212 peptidyl-tyrosine modification 1.108913e-3
GO:0042407 cristae formation 1.126759e-3
GO:0035803 egg coat formation 1.126759e-3
GO:0072592 oxygen metabolic process 1.145771e-3
GO:0010966 regulation of phosphate transport 1.145771e-3
GO:0033002 muscle cell proliferation 1.154671e-3
GO:0006687 glycosphingolipid metabolic process 1.160809e-3
GO:0051301 cell division 1.168652e-3
GO:0030010 establishment of cell polarity 1.173373e-3
GO:0040001 establishment of mitotic spindle localization 1.199561e-3
GO:0000724 double-strand break repair via homologous recombination 1.246133e-3
GO:0006361 transcription initiation from RNA polymerase I promoter 1.260058e-3
GO:2000774 positive regulation of cellular senescence 1.266736e-3
GO:0035986 senescence-associated heterochromatin focus formation 1.266736e-3
GO:0060556 regulation of vitamin D biosynthetic process 1.279819e-3
GO:0033007 negative regulation of mast cell activation involved in immune response 1.285464e-3
GO:0051321 meiotic cell cycle 1.301646e-3
GO:0007341 penetration of zona pellucida 1.317373e-3
GO:0006233 dTDP biosynthetic process 1.318402e-3
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation 1.381746e-3
GO:0050434 positive regulation of viral transcription 1.409240e-3
GO:0018108 peptidyl-tyrosine phosphorylation 1.418760e-3
GO:0030889 negative regulation of B cell proliferation 1.445842e-3
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway 1.446452e-3
GO:0071480 cellular response to gamma radiation 1.464810e-3
GO:0008366 axon ensheathment 1.492495e-3
GO:0032890 regulation of organic acid transport 1.505768e-3
GO:0016567 protein ubiquitination 1.518503e-3
GO:0000725 recombinational repair 1.554751e-3
GO:0051726 regulation of cell cycle 1.583315e-3
GO:0060033 anatomical structure regression 1.596939e-3
GO:0006538 glutamate catabolic process 1.599260e-3
GO:0043633 polyadenylation-dependent RNA catabolic process 1.653904e-3
GO:0032287 peripheral nervous system myelin maintenance 1.677168e-3
GO:0051549 positive regulation of keratinocyte migration 1.682020e-3
GO:0006911 phagocytosis, engulfment 1.708613e-3
GO:0006414 translational elongation 1.728536e-3
GO:0046782 regulation of viral transcription 1.785014e-3
GO:0060576 intestinal epithelial cell development 1.822516e-3
GO:0008054 cyclin catabolic process 1.824883e-3
GO:0050881 musculoskeletal movement 1.840212e-3
GO:0000712 resolution of meiotic recombination intermediates 1.841858e-3
GO:0070830 tight junction assembly 1.867604e-3
GO:0010956 negative regulation of calcidiol 1-monooxygenase activity 1.893049e-3
GO:0009138 pyrimidine nucleoside diphosphate metabolic process 1.917688e-3
GO:0002769 natural killer cell inhibitory signaling pathway 1.968277e-3
GO:0046513 ceramide biosynthetic process 1.995251e-3
GO:0000132 establishment of mitotic spindle orientation 2.006860e-3
GO:0006382 adenosine to inosine editing 2.031854e-3
GO:0006689 ganglioside catabolic process 2.054198e-3
GO:0008033 tRNA processing 2.062706e-3
GO:0042572 retinol metabolic process 2.085344e-3
GO:0050769 positive regulation of neurogenesis 2.092485e-3
GO:0019673 GDP-mannose metabolic process 2.102137e-3
GO:0015696 ammonium transport 2.136997e-3
GO:0070206 protein trimerization 2.249820e-3
GO:0002312 B cell activation involved in immune response 2.278861e-3
GO:0006573 valine metabolic process 2.330045e-3
GO:0002344 B cell affinity maturation 2.346531e-3
GO:2000467 positive regulation of glycogen (starch) synthase activity 2.355937e-3
GO:0048678 response to axon injury 2.380657e-3
GO:0000083 regulation of transcription involved in G1/S phase of mitotic cell cycle 2.453325e-3
GO:0006139 nucleobase-containing compound metabolic process 2.484103e-3
GO:0045879 negative regulation of smoothened signaling pathway 2.554319e-3
GO:0019985 translesion synthesis 2.590416e-3
GO:0003219 cardiac right ventricle formation 2.590416e-3
GO:0006684 sphingomyelin metabolic process 2.634688e-3
GO:0071422 succinate transmembrane transport 2.715849e-3
GO:0071894 histone H2B conserved C-terminal lysine ubiquitination 2.738704e-3
GO:0031129 inductive cell-cell signaling 2.738704e-3
GO:0014827 intestine smooth muscle contraction 2.789392e-3
GO:2000737 negative regulation of stem cell differentiation 2.795916e-3
GO:0035020 regulation of Rac protein signal transduction 2.797910e-3
GO:0006665 sphingolipid metabolic process 2.918493e-3
GO:0032446 protein modification by small protein conjugation 2.966641e-3
GO:0042552 myelination 2.995048e-3
GO:0035411 catenin import into nucleus 3.001088e-3
GO:0032107 regulation of response to nutrient levels 3.018411e-3
GO:0007346 regulation of mitotic cell cycle 3.048281e-3
GO:2000191 regulation of fatty acid transport 3.103671e-3
GO:0006337 nucleosome disassembly 3.121319e-3
GO:0048025 negative regulation of nuclear mRNA splicing, via spliceosome 3.155280e-3
GO:0008089 anterograde axon cargo transport 3.169668e-3
GO:0046006 regulation of activated T cell proliferation 3.172595e-3
GO:0045919 positive regulation of cytolysis 3.204314e-3
GO:0043039 tRNA aminoacylation 3.212337e-3
GO:0071344 diphosphate metabolic process 3.218601e-3
GO:0030187 melatonin biosynthetic process 3.218601e-3
GO:0046931 pore complex assembly 3.443318e-3
GO:0030221 basophil differentiation 3.467032e-3
GO:2000379 positive regulation of reactive oxygen species metabolic process 3.486549e-3
GO:0043616 keratinocyte proliferation 3.536227e-3
GO:0001936 regulation of endothelial cell proliferation 3.589957e-3
GO:0070207 protein homotrimerization 3.596745e-3
GO:0060534 trachea cartilage development 3.604619e-3
GO:0051298 centrosome duplication 3.678880e-3
GO:0048194 Golgi vesicle budding 3.688612e-3
GO:0046479 glycosphingolipid catabolic process 3.688612e-3
GO:0006913 nucleocytoplasmic transport 3.713870e-3
GO:0001893 maternal placenta development 3.733579e-3
GO:0046520 sphingoid biosynthetic process 3.744967e-3
GO:0071636 positive regulation of transforming growth factor beta production 3.845772e-3
GO:0045653 negative regulation of megakaryocyte differentiation 3.896845e-3
GO:0055017 cardiac muscle tissue growth 3.922874e-3
GO:0009988 cell-cell recognition 4.112029e-3
GO:0006108 malate metabolic process 4.167103e-3
GO:0006334 nucleosome assembly 4.199097e-3
GO:2000177 regulation of neural precursor cell proliferation 4.269602e-3
GO:0043297 apical junction assembly 4.305575e-3
GO:0050772 positive regulation of axonogenesis 4.310060e-3
GO:0018293 protein-FAD linkage 4.362245e-3
GO:0051388 positive regulation of nerve growth factor receptor signaling pathway 4.362245e-3
GO:0010963 regulation of L-arginine import 4.362245e-3
GO:0006121 mitochondrial electron transport, succinate to ubiquinone 4.362245e-3
GO:0021986 habenula development 4.396748e-3
GO:0001561 fatty acid alpha-oxidation 4.546090e-3
GO:0051297 centrosome organization 4.563155e-3
GO:0045556 positive regulation of TRAIL biosynthetic process 4.641710e-3
GO:0046628 positive regulation of insulin receptor signaling pathway 4.691423e-3
GO:0043415 positive regulation of skeletal muscle tissue regeneration 4.728447e-3
GO:0010693 negative regulation of alkaline phosphatase activity 4.728447e-3
GO:0071103 DNA conformation change 4.755634e-3
GO:0043648 dicarboxylic acid metabolic process 4.761102e-3
GO:0000216 M/G1 transition of mitotic cell cycle 4.860810e-3
GO:0006686 sphingomyelin biosynthetic process 4.918868e-3
GO:0045116 protein neddylation 4.946254e-3
GO:0042351 'de novo' GDP-L-fucose biosynthetic process 4.982169e-3
GO:0009313 oligosaccharide catabolic process 4.993129e-3
GO:0032984 macromolecular complex disassembly 5.002429e-3
GO:0002329 pre-B cell differentiation 5.052892e-3
GO:0034623 cellular macromolecular complex disassembly 5.084685e-3
GO:0019228 regulation of action potential in neuron 5.100547e-3
GO:0006612 protein targeting to membrane 5.132120e-3
GO:0015074 DNA integration 5.170556e-3
GO:0010720 positive regulation of cell development 5.232421e-3
GO:0072274 metanephric glomerular basement membrane development 5.233928e-3
GO:0072249 metanephric glomerular visceral epithelial cell development 5.233928e-3
GO:0048677 axon extension involved in regeneration 5.233928e-3
GO:0018931 naphthalene metabolic process 5.233928e-3
GO:0035284 brain segmentation 5.263951e-3
GO:0060419 heart growth 5.365347e-3
GO:0048167 regulation of synaptic plasticity 5.391073e-3
GO:0045541 negative regulation of cholesterol biosynthetic process 5.416900e-3
GO:0070995 NADPH oxidation 5.432148e-3
GO:0003218 cardiac left ventricle formation 5.432148e-3
GO:0035814 negative regulation of renal sodium excretion 5.453243e-3
GO:0045939 negative regulation of steroid metabolic process 5.473623e-3
GO:0015801 aromatic amino acid transport 5.487684e-3
GO:0055094 response to lipoprotein stimulus 5.504268e-3
GO:0060482 lobar bronchus development 5.548681e-3
GO:0043985 histone H4-R3 methylation 5.548681e-3
GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification 5.548681e-3
GO:0021776 smoothened signaling pathway involved in spinal cord motor neuron cell fate specification 5.548681e-3
GO:0010894 negative regulation of steroid biosynthetic process 5.708628e-3
GO:0019060 intracellular transport of viral proteins in host cell 5.724285e-3
GO:0033004 negative regulation of mast cell activation 5.734555e-3
GO:0015804 neutral amino acid transport 5.767344e-3
GO:0051169 nuclear transport 5.777363e-3
GO:0045292 nuclear mRNA cis splicing, via spliceosome 5.813574e-3
GO:0030833 regulation of actin filament polymerization 5.867614e-3
GO:0006415 translational termination 5.976916e-3
GO:0060038 cardiac muscle cell proliferation 6.133955e-3
GO:0022417 protein maturation by protein folding 6.207424e-3
GO:0006403 RNA localization 6.257998e-3
GO:0048619 embryonic hindgut morphogenesis 6.290609e-3
GO:0008611 ether lipid biosynthetic process 6.462771e-3
GO:0006477 protein sulfation 6.507719e-3
GO:0042053 regulation of dopamine metabolic process 6.533977e-3
GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process 6.579873e-3
GO:0018352 protein-pyridoxal-5-phosphate linkage 6.717439e-3
GO:0006418 tRNA aminoacylation for protein translation 6.755074e-3
GO:0006323 DNA packaging 6.981245e-3
GO:0043535 regulation of blood vessel endothelial cell migration 7.036835e-3
GO:0043217 myelin maintenance 7.042275e-3
GO:0019048 virus-host interaction 7.107281e-3
GO:0002544 chronic inflammatory response 7.165985e-3
GO:0010940 positive regulation of necrotic cell death 7.187479e-3
GO:0021515 cell differentiation in spinal cord 7.223761e-3
GO:0006614 SRP-dependent cotranslational protein targeting to membrane 7.240678e-3
GO:0051292 nuclear pore complex assembly 7.247684e-3
GO:0042694 muscle cell fate specification 7.247684e-3
GO:0019323 pentose catabolic process 7.247684e-3
GO:0002339 B cell selection 7.247684e-3
GO:0016572 histone phosphorylation 7.272727e-3
GO:0006556 S-adenosylmethionine biosynthetic process 7.273085e-3
GO:0035094 response to nicotine 7.277367e-3
GO:0045333 cellular respiration 7.332614e-3
GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process 7.443102e-3
GO:0019376 galactolipid catabolic process 7.443102e-3
GO:0031023 microtubule organizing center organization 7.503873e-3
GO:0033554 cellular response to stress 7.591581e-3
GO:0050658 RNA transport 7.637499e-3
GO:0050686 negative regulation of mRNA processing 7.642883e-3
GO:2000465 regulation of glycogen (starch) synthase activity 7.647611e-3
GO:0006402 mRNA catabolic process 7.669121e-3
GO:0008078 mesodermal cell migration 7.707798e-3
GO:0032185 septin cytoskeleton organization 7.707798e-3
GO:0034637 cellular carbohydrate biosynthetic process 7.787227e-3
GO:0031297 replication fork processing 7.809477e-3
GO:0001881 receptor recycling 7.917376e-3
GO:0031104 dendrite regeneration 8.066244e-3
GO:0031508 centromeric heterochromatin formation 8.066244e-3
GO:0043382 positive regulation of memory T cell differentiation 8.159647e-3
GO:0010498 proteasomal protein catabolic process 8.246851e-3
GO:0042069 regulation of catecholamine metabolic process 8.353663e-3
GO:0006670 sphingosine metabolic process 8.376842e-3
GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c 8.424536e-3
GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development 8.441034e-3
GO:0006667 sphinganine metabolic process 8.441034e-3
GO:0045005 maintenance of fidelity involved in DNA-dependent DNA replication 8.453573e-3
GO:0043523 regulation of neuron apoptosis 8.493691e-3
GO:0019896 axon transport of mitochondrion 8.536142e-3
GO:0043161 proteasomal ubiquitin-dependent protein catabolic process 8.672063e-3
GO:0031118 rRNA pseudouridine synthesis 8.701731e-3


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0007088 regulation of mitosis 4.420078e-13
GO:0014902 myotube differentiation 3.526030e-12
GO:0045840 positive regulation of mitosis 1.135514e-11
GO:0010800 positive regulation of peptidyl-threonine phosphorylation 8.416602e-11
GO:0007346 regulation of mitotic cell cycle 1.210589e-10
GO:0010799 regulation of peptidyl-threonine phosphorylation 2.141762e-10
GO:0051450 myoblast proliferation 6.888799e-10
GO:0010467 gene expression 2.058895e-9
GO:0010564 regulation of cell cycle process 8.529110e-9
GO:0043973 histone H3-K4 acetylation 1.051110e-8
GO:0046985 positive regulation of hemoglobin biosynthetic process 1.051110e-8
GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery 1.051110e-8
GO:0042760 very long-chain fatty acid catabolic process 1.058705e-8
GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 1.266917e-8
GO:0090068 positive regulation of cell cycle process 1.812038e-8
GO:0035019 somatic stem cell maintenance 2.439157e-8
GO:0035914 skeletal muscle cell differentiation 2.507623e-8
GO:0014834 satellite cell maintenance involved in skeletal muscle regeneration 2.624565e-8
GO:0060840 artery development 4.227257e-8
GO:0010801 negative regulation of peptidyl-threonine phosphorylation 6.217255e-8
GO:0031016 pancreas development 7.808349e-8
GO:0002536 respiratory burst involved in inflammatory response 8.403031e-8
GO:0034447 very-low-density lipoprotein particle clearance 1.082281e-7
GO:0014904 myotube cell development 2.163231e-7
GO:0060509 Type I pneumocyte differentiation 2.319856e-7
GO:0021533 cell differentiation in hindbrain 2.980526e-7
GO:0010900 negative regulation of phosphatidylcholine catabolic process 3.141362e-7
GO:0035674 tricarboxylic acid transmembrane transport 3.492429e-7
GO:0016070 RNA metabolic process 4.961036e-7
GO:0044260 cellular macromolecule metabolic process 5.902747e-7
GO:0090304 nucleic acid metabolic process 6.009753e-7
GO:0048844 artery morphogenesis 6.716604e-7
GO:0009889 regulation of biosynthetic process 6.756719e-7
GO:0046984 regulation of hemoglobin biosynthetic process 7.090027e-7
GO:0042522 regulation of tyrosine phosphorylation of Stat5 protein 7.900699e-7
GO:0035272 exocrine system development 8.320308e-7
GO:0006401 RNA catabolic process 8.759538e-7
GO:0071354 cellular response to interleukin-6 9.141512e-7
GO:0044237 cellular metabolic process 9.439644e-7
GO:0045862 positive regulation of proteolysis 1.034371e-6
GO:0000726 non-recombinational repair 1.215309e-6
GO:0006303 double-strand break repair via nonhomologous end joining 1.256714e-6
GO:0007067 mitosis 1.836082e-6
GO:0048863 stem cell differentiation 2.087197e-6
GO:0000226 microtubule cytoskeleton organization 2.133725e-6
GO:0006139 nucleobase-containing compound metabolic process 2.248028e-6
GO:0045596 negative regulation of cell differentiation 2.278393e-6
GO:0032270 positive regulation of cellular protein metabolic process 2.312087e-6
GO:0031326 regulation of cellular biosynthetic process 2.313241e-6
GO:0051247 positive regulation of protein metabolic process 2.374680e-6
GO:0071243 cellular response to arsenic-containing substance 2.792059e-6
GO:0060766 negative regulation of androgen receptor signaling pathway 3.023700e-6
GO:0048285 organelle fission 3.297177e-6
GO:0060741 prostate gland stromal morphogenesis 3.362559e-6
GO:0048864 stem cell development 3.487678e-6
GO:0001764 neuron migration 3.663049e-6
GO:0000387 spliceosomal snRNP assembly 3.768727e-6
GO:0000087 M phase of mitotic cell cycle 3.874863e-6
GO:0014812 muscle cell migration 4.206778e-6
GO:0043170 macromolecule metabolic process 4.222550e-6
GO:0033238 regulation of cellular amine metabolic process 4.256502e-6
GO:0046785 microtubule polymerization 4.486108e-6
GO:0035630 bone mineralization involved in bone maturation 4.486108e-6
GO:0000089 mitotic metaphase 4.827022e-6
GO:0071034 CUT catabolic process 5.292461e-6
GO:0010994 free ubiquitin chain polymerization 5.292461e-6
GO:0010556 regulation of macromolecule biosynthetic process 5.530698e-6
GO:0019827 stem cell maintenance 6.039615e-6
GO:0045188 regulation of circadian sleep/wake cycle, non-REM sleep 6.167285e-6
GO:0042769 DNA damage response, detection of DNA damage 6.232567e-6
GO:0031017 exocrine pancreas development 6.495973e-6
GO:0008334 histone mRNA metabolic process 6.820555e-6
GO:0016055 Wnt receptor signaling pathway 7.753458e-6
GO:0008152 metabolic process 8.848701e-6
GO:2000112 regulation of cellular macromolecule biosynthetic process 9.108496e-6
GO:0008380 RNA splicing 9.974226e-6
GO:0014911 positive regulation of smooth muscle cell migration 1.045933e-5
GO:0051651 maintenance of location in cell 1.100426e-5
GO:0051235 maintenance of location 1.101010e-5
GO:0060463 lung lobe morphogenesis 1.175399e-5
GO:0006396 RNA processing 1.206451e-5
GO:0043403 skeletal muscle tissue regeneration 1.213212e-5
GO:0044238 primary metabolic process 1.272772e-5
GO:0051171 regulation of nitrogen compound metabolic process 1.329023e-5
GO:0006275 regulation of DNA replication 1.352588e-5
GO:0033239 negative regulation of cellular amine metabolic process 1.355656e-5
GO:0034661 ncRNA catabolic process 1.372510e-5
GO:0015746 citrate transport 1.420497e-5
GO:0080164 regulation of nitric oxide metabolic process 1.458527e-5
GO:0007057 spindle assembly involved in female meiosis I 1.458527e-5
GO:0046777 protein autophosphorylation 1.638777e-5
GO:0042753 positive regulation of circadian rhythm 1.791346e-5
GO:0034641 cellular nitrogen compound metabolic process 1.875173e-5
GO:0048538 thymus development 1.928554e-5
GO:0071044 histone mRNA catabolic process 2.021318e-5
GO:0034392 negative regulation of smooth muscle cell apoptosis 2.022027e-5
GO:0030970 retrograde protein transport, ER to cytosol 2.080766e-5
GO:0031536 positive regulation of exit from mitosis 2.156144e-5
GO:0044330 canonical Wnt receptor signaling pathway involved in positive regulation of wound healing 2.389887e-5
GO:0044328 canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration 2.389887e-5
GO:0044329 canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion 2.389887e-5
GO:0001676 long-chain fatty acid metabolic process 2.581067e-5
GO:0043931 ossification involved in bone maturation 2.638611e-5
GO:0030071 regulation of mitotic metaphase/anaphase transition 2.775428e-5
GO:0042104 positive regulation of activated T cell proliferation 2.807581e-5
GO:0032007 negative regulation of TOR signaling cascade 2.960979e-5
GO:0009892 negative regulation of metabolic process 3.072126e-5
GO:0016071 mRNA metabolic process 3.254271e-5
GO:0046890 regulation of lipid biosynthetic process 3.378148e-5
GO:0051005 negative regulation of lipoprotein lipase activity 3.390541e-5
GO:0034382 chylomicron remnant clearance 3.390541e-5
GO:0009057 macromolecule catabolic process 3.534176e-5
GO:0060696 regulation of phospholipid catabolic process 3.559922e-5
GO:0060736 prostate gland growth 3.565835e-5
GO:0050995 negative regulation of lipid catabolic process 3.657295e-5
GO:0071422 succinate transmembrane transport 3.845123e-5
GO:0046426 negative regulation of JAK-STAT cascade 3.930469e-5
GO:0060319 primitive erythrocyte differentiation 4.096227e-5
GO:0060192 negative regulation of lipase activity 4.098473e-5
GO:0006357 regulation of transcription from RNA polymerase II promoter 4.098969e-5
GO:0006807 nitrogen compound metabolic process 4.582738e-5
GO:0021522 spinal cord motor neuron differentiation 4.930215e-5
GO:0021940 positive regulation of cerebellar granule cell precursor proliferation 4.957693e-5
GO:0032784 regulation of transcription elongation, DNA-dependent 5.197414e-5
GO:0033144 negative regulation of steroid hormone receptor signaling pathway 5.748026e-5
GO:0070541 response to platinum ion 5.873912e-5
GO:0070741 response to interleukin-6 5.949032e-5
GO:0070977 bone maturation 6.204543e-5
GO:2000381 negative regulation of mesoderm development 6.360741e-5
GO:0031129 inductive cell-cell signaling 6.535724e-5
GO:0060510 Type II pneumocyte differentiation 6.641766e-5
GO:0021697 cerebellar cortex formation 6.644681e-5
GO:0051258 protein polymerization 7.135390e-5
GO:0045595 regulation of cell differentiation 7.287512e-5
GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly 7.576855e-5
GO:0015931 nucleobase-containing compound transport 7.606559e-5
GO:0009059 macromolecule biosynthetic process 7.690191e-5
GO:0019219 regulation of nucleobase-containing compound metabolic process 7.747126e-5
GO:0002320 lymphoid progenitor cell differentiation 8.091792e-5
GO:0048713 regulation of oligodendrocyte differentiation 8.579513e-5
GO:0007398 ectoderm development 8.719397e-5
GO:0045740 positive regulation of DNA replication 8.782614e-5
GO:0002328 pro-B cell differentiation 8.935279e-5
GO:0021515 cell differentiation in spinal cord 8.953442e-5
GO:0050810 regulation of steroid biosynthetic process 9.009878e-5
GO:0045732 positive regulation of protein catabolic process 9.016527e-5
GO:0032900 negative regulation of neurotrophin production 9.194669e-5
GO:0051315 attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation 9.194669e-5
GO:0032244 positive regulation of nucleoside transport 9.194669e-5
GO:0010468 regulation of gene expression 9.203553e-5
GO:0006397 mRNA processing 9.601761e-5
GO:0000278 mitotic cell cycle 9.738791e-5
GO:0042524 negative regulation of tyrosine phosphorylation of Stat5 protein 9.761053e-5
GO:2000172 regulation of branching morphogenesis of a nerve 9.761053e-5
GO:0055123 digestive system development 9.896534e-5
GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein 9.905117e-5
GO:0009890 negative regulation of biosynthetic process 9.972568e-5
GO:0042752 regulation of circadian rhythm 1.009902e-4
GO:0021936 regulation of cerebellar granule cell precursor proliferation 1.032673e-4
GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep 1.035416e-4
GO:0001649 osteoblast differentiation 1.047328e-4
GO:0071322 cellular response to carbohydrate stimulus 1.057558e-4
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 1.110596e-4
GO:0044265 cellular macromolecule catabolic process 1.146315e-4
GO:0019836 hemolysis by symbiont of host erythrocytes 1.160106e-4
GO:0060992 response to fungicide 1.171107e-4
GO:0010638 positive regulation of organelle organization 1.208560e-4
GO:0031331 positive regulation of cellular catabolic process 1.219502e-4
GO:0046006 regulation of activated T cell proliferation 1.225317e-4
GO:0010519 negative regulation of phospholipase activity 1.299714e-4
GO:0006168 adenine salvage 1.299714e-4
GO:0000122 negative regulation of transcription from RNA polymerase II promoter 1.304767e-4
GO:0002244 hemopoietic progenitor cell differentiation 1.311948e-4
GO:0006699 bile acid biosynthetic process 1.333153e-4
GO:0034645 cellular macromolecule biosynthetic process 1.355260e-4
GO:0001522 pseudouridine synthesis 1.367608e-4
GO:0048333 mesodermal cell differentiation 1.391142e-4
GO:0006412 translation 1.565804e-4
GO:0000956 nuclear-transcribed mRNA catabolic process 1.602664e-4
GO:0060765 regulation of androgen receptor signaling pathway 1.607220e-4
GO:0060458 right lung development 1.624647e-4
GO:0021702 cerebellar Purkinje cell differentiation 1.637789e-4
GO:0034391 regulation of smooth muscle cell apoptosis 1.647008e-4
GO:0071877 regulation of adrenergic receptor signaling pathway 1.711481e-4
GO:0031327 negative regulation of cellular biosynthetic process 1.734861e-4
GO:0006284 base-excision repair 1.759259e-4
GO:0045445 myoblast differentiation 1.793848e-4
GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway 1.828290e-4
GO:0060644 mammary gland epithelial cell differentiation 1.859579e-4
GO:0010310 regulation of hydrogen peroxide metabolic process 1.905430e-4
GO:0045938 positive regulation of circadian sleep/wake cycle, sleep 1.909719e-4
GO:0010656 negative regulation of muscle cell apoptosis 1.948714e-4
GO:0014050 negative regulation of glutamate secretion 1.964377e-4
GO:0051252 regulation of RNA metabolic process 2.027339e-4
GO:0061136 regulation of proteasomal protein catabolic process 2.070382e-4
GO:0000279 M phase 2.096070e-4
GO:0048566 embryonic digestive tract development 2.269230e-4
GO:0045833 negative regulation of lipid metabolic process 2.339705e-4
GO:0006116 NADH oxidation 2.345986e-4
GO:0046325 negative regulation of glucose import 2.352623e-4
GO:0032077 positive regulation of deoxyribonuclease activity 2.360593e-4
GO:0051323 metaphase 2.365537e-4
GO:0070979 protein K11-linked ubiquitination 2.377335e-4
GO:0048012 hepatocyte growth factor receptor signaling pathway 2.438826e-4
GO:0051897 positive regulation of protein kinase B signaling cascade 2.463526e-4
GO:0021696 cerebellar cortex morphogenesis 2.540914e-4
GO:0051257 spindle midzone assembly involved in meiosis 2.594976e-4
GO:0051301 cell division 2.663847e-4
GO:0006355 regulation of transcription, DNA-dependent 2.685284e-4
GO:0021517 ventral spinal cord development 2.737763e-4
GO:0006403 RNA localization 2.761243e-4
GO:0071773 cellular response to BMP stimulus 2.833729e-4
GO:0045540 regulation of cholesterol biosynthetic process 2.836392e-4
GO:0060070 canonical Wnt receptor signaling pathway 2.877605e-4
GO:0031324 negative regulation of cellular metabolic process 2.936140e-4
GO:0060574 intestinal epithelial cell maturation 3.035557e-4
GO:0051093 negative regulation of developmental process 3.181266e-4
GO:0031133 regulation of axon diameter 3.234599e-4
GO:0051172 negative regulation of nitrogen compound metabolic process 3.320270e-4
GO:0016075 rRNA catabolic process 3.336672e-4
GO:0010458 exit from mitosis 3.377606e-4
GO:0010829 negative regulation of glucose transport 3.386597e-4
GO:0051052 regulation of DNA metabolic process 3.647817e-4
GO:0007040 lysosome organization 3.712973e-4
GO:2000113 negative regulation of cellular macromolecule biosynthetic process 3.726327e-4
GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process 3.800684e-4
GO:0010558 negative regulation of macromolecule biosynthetic process 3.853408e-4
GO:0019216 regulation of lipid metabolic process 3.887490e-4
GO:0045725 positive regulation of glycogen biosynthetic process 3.970970e-4
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 4.152649e-4
GO:0032878 regulation of establishment or maintenance of cell polarity 4.197830e-4
GO:0031109 microtubule polymerization or depolymerization 4.197830e-4
GO:0032864 activation of Cdc42 GTPase activity 4.208547e-4
GO:0044249 cellular biosynthetic process 4.293983e-4
GO:0034241 positive regulation of macrophage fusion 4.386233e-4
GO:0031468 nuclear envelope reassembly 4.386233e-4
GO:0050793 regulation of developmental process 4.494609e-4
GO:0045187 regulation of circadian sleep/wake cycle, sleep 4.499364e-4
GO:0060348 bone development 4.592293e-4
GO:0006561 proline biosynthetic process 4.661484e-4
GO:0035414 negative regulation of catenin import into nucleus 4.738128e-4
GO:0009058 biosynthetic process 4.790021e-4
GO:0019835 cytolysis 4.885615e-4
GO:0045892 negative regulation of transcription, DNA-dependent 4.890429e-4
GO:0060981 cell migration involved in coronary angiogenesis 4.938493e-4
GO:0046038 GMP catabolic process 4.938493e-4
GO:0071670 smooth muscle cell chemotaxis 4.938493e-4
GO:0006178 guanine salvage 4.938493e-4
GO:0032263 GMP salvage 4.938493e-4
GO:0032264 IMP salvage 4.938493e-4
GO:0010629 negative regulation of gene expression 4.989802e-4
GO:0010001 glial cell differentiation 5.087415e-4
GO:0060688 regulation of morphogenesis of a branching structure 5.183358e-4
GO:0006402 mRNA catabolic process 5.196938e-4
GO:0080090 regulation of primary metabolic process 5.212809e-4
GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration 5.403265e-4
GO:0001708 cell fate specification 5.435534e-4
GO:0051640 organelle localization 5.482137e-4
GO:0007017 microtubule-based process 5.546717e-4
GO:0046037 GMP metabolic process 5.561372e-4
GO:0051152 positive regulation of smooth muscle cell differentiation 5.662906e-4
GO:0051310 metaphase plate congression 5.714209e-4
GO:0051642 centrosome localization 5.848652e-4
GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway 5.856872e-4
GO:0060662 salivary gland cavitation 6.031043e-4
GO:0090201 negative regulation of release of cytochrome c from mitochondria 6.141902e-4
GO:0010605 negative regulation of macromolecule metabolic process 6.163226e-4
GO:0000212 meiotic spindle organization 6.199222e-4
GO:0010660 regulation of muscle cell apoptosis 6.204943e-4
GO:0042176 regulation of protein catabolic process 6.207906e-4
GO:2000179 positive regulation of neural precursor cell proliferation 6.237261e-4
GO:0015986 ATP synthesis coupled proton transport 6.343851e-4
GO:0042523 positive regulation of tyrosine phosphorylation of Stat5 protein 6.483003e-4
GO:0071294 cellular response to zinc ion 6.510037e-4
GO:0051574 positive regulation of histone H3-K9 methylation 6.510037e-4
GO:0007096 regulation of exit from mitosis 6.510037e-4
GO:2000467 positive regulation of glycogen (starch) synthase activity 6.697975e-4
GO:0032851 positive regulation of Rab GTPase activity 6.900703e-4
GO:0006266 DNA ligation 6.939700e-4
GO:0046823 negative regulation of nucleocytoplasmic transport 6.963876e-4
GO:0002377 immunoglobulin production 7.084035e-4
GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter 7.161482e-4
GO:0008277 regulation of G-protein coupled receptor protein signaling pathway 7.284897e-4
GO:0032536 regulation of cell projection size 7.365025e-4
GO:0009896 positive regulation of catabolic process 7.462870e-4
GO:2000173 negative regulation of branching morphogenesis of a nerve 7.485161e-4
GO:0006420 arginyl-tRNA aminoacylation 7.485161e-4
GO:0032313 regulation of Rab GTPase activity 7.497841e-4
GO:0006641 triglyceride metabolic process 7.606923e-4
GO:0060764 cell-cell signaling involved in mammary gland development 7.616568e-4
GO:0018924 mandelate metabolic process 7.616568e-4
GO:0048523 negative regulation of cellular process 7.784999e-4
GO:0051044 positive regulation of membrane protein ectodomain proteolysis 7.823400e-4
GO:0018026 peptidyl-lysine monomethylation 7.823400e-4
GO:0008333 endosome to lysosome transport 7.871006e-4
GO:0010232 vascular transport 7.943439e-4
GO:2000384 negative regulation of ectoderm development 7.943439e-4
GO:0014910 regulation of smooth muscle cell migration 8.014145e-4
GO:0002440 production of molecular mediator of immune response 8.085099e-4
GO:0031323 regulation of cellular metabolic process 8.208503e-4
GO:0060174 limb bud formation 8.265739e-4
GO:0060973 cell migration involved in heart development 8.365659e-4
GO:0007093 mitotic cell cycle checkpoint 8.641631e-4
GO:0007625 grooming behavior 8.733212e-4
GO:0071333 cellular response to glucose stimulus 8.752533e-4
GO:0010823 negative regulation of mitochondrion organization 8.800200e-4
GO:0045653 negative regulation of megakaryocyte differentiation 8.813324e-4
GO:0006657 CDP-choline pathway 8.813324e-4
GO:0051726 regulation of cell cycle 8.865468e-4
GO:0050884 neuromuscular process controlling posture 8.940450e-4
GO:0010985 negative regulation of lipoprotein particle clearance 8.973393e-4
GO:2000009 negative regulation of protein localization at cell surface 9.004814e-4
GO:0006683 galactosylceramide catabolic process 9.004814e-4
GO:0045769 negative regulation of asymmetric cell division 9.004814e-4
GO:0008612 peptidyl-lysine modification to hypusine 9.013430e-4
GO:0050658 RNA transport 9.101718e-4
GO:0045821 positive regulation of glycolysis 9.477842e-4
GO:0031401 positive regulation of protein modification process 9.563561e-4
GO:0060487 lung epithelial cell differentiation 9.744118e-4
GO:0030282 bone mineralization 9.744118e-4
GO:2000026 regulation of multicellular organismal development 9.765852e-4
GO:0070875 positive regulation of glycogen metabolic process 9.807558e-4
GO:0016998 cell wall macromolecule catabolic process 9.858209e-4
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 9.877701e-4
GO:0001570 vasculogenesis 9.897269e-4
GO:2000177 regulation of neural precursor cell proliferation 1.001020e-3
GO:0045844 positive regulation of striated muscle tissue development 1.012660e-3
GO:0051782 negative regulation of cell division 1.013607e-3
GO:0002036 regulation of L-glutamate transport 1.015502e-3
GO:0043587 tongue morphogenesis 1.016164e-3
GO:0034622 cellular macromolecular complex assembly 1.036101e-3
GO:0001933 negative regulation of protein phosphorylation 1.069794e-3
GO:0002344 B cell affinity maturation 1.081106e-3
GO:0045647 negative regulation of erythrocyte differentiation 1.094897e-3
GO:0001501 skeletal system development 1.110482e-3
GO:0042509 regulation of tyrosine phosphorylation of STAT protein 1.115998e-3
GO:0032241 positive regulation of nucleobase-containing compound transport 1.124594e-3
GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine 1.124594e-3
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 1.145534e-3
GO:0051253 negative regulation of RNA metabolic process 1.159925e-3
GO:0060693 regulation of branching involved in salivary gland morphogenesis 1.160815e-3
GO:0010827 regulation of glucose transport 1.168863e-3
GO:0051313 attachment of spindle microtubules to chromosome 1.175257e-3
GO:0060255 regulation of macromolecule metabolic process 1.199375e-3
GO:0007519 skeletal muscle tissue development 1.234370e-3
GO:0034621 cellular macromolecular complex subunit organization 1.269151e-3
GO:0043096 purine base salvage 1.282285e-3
GO:0002439 chronic inflammatory response to antigenic stimulus 1.285337e-3
GO:0072092 ureteric bud invasion 1.345212e-3
GO:0070836 caveola assembly 1.345228e-3
GO:0043060 meiotic metaphase I plate congression 1.345228e-3
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 1.353939e-3
GO:0060024 rhythmic synaptic transmission 1.356288e-3
GO:0048732 gland development 1.358181e-3
GO:0051303 establishment of chromosome localization 1.368237e-3
GO:0001503 ossification 1.394521e-3
GO:0072500 negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor 1.427957e-3
GO:2000647 negative regulation of stem cell proliferation 1.427957e-3
GO:0071247 cellular response to chromate 1.427957e-3
GO:0010933 positive regulation of macrophage tolerance induction 1.427957e-3
GO:0070563 negative regulation of vitamin D receptor signaling pathway 1.427957e-3
GO:0010839 negative regulation of keratinocyte proliferation 1.427957e-3
GO:0035921 desmosome disassembly 1.427957e-3
GO:0006367 transcription initiation from RNA polymerase II promoter 1.451281e-3
GO:0043567 regulation of insulin-like growth factor receptor signaling pathway 1.501034e-3
GO:0018202 peptidyl-histidine modification 1.524022e-3
GO:0002679 respiratory burst involved in defense response 1.524022e-3
GO:0060123 regulation of growth hormone secretion 1.535811e-3
GO:0071286 cellular response to magnesium ion 1.573476e-3
GO:2000383 regulation of ectoderm development 1.600855e-3
GO:0006177 GMP biosynthetic process 1.600855e-3
GO:0006449 regulation of translational termination 1.600855e-3
GO:0002541 activation of plasma proteins involved in acute inflammatory response 1.601316e-3
GO:0060312 regulation of blood vessel remodeling 1.624259e-3
GO:0014816 satellite cell differentiation 1.624259e-3
GO:0071695 anatomical structure maturation 1.631138e-3
GO:0001919 regulation of receptor recycling 1.635526e-3
GO:2000679 positive regulation of transcription regulatory region DNA binding 1.672292e-3
GO:0001921 positive regulation of receptor recycling 1.672292e-3
GO:0090181 regulation of cholesterol metabolic process 1.715283e-3
GO:0042063 gliogenesis 1.730574e-3
GO:0006366 transcription from RNA polymerase II promoter 1.748731e-3
GO:0033484 nitric oxide homeostasis 1.753595e-3
GO:0008054 cyclin catabolic process 1.763327e-3
GO:0006351 transcription, DNA-dependent 1.771641e-3
GO:0048643 positive regulation of skeletal muscle tissue development 1.783878e-3
GO:0051055 negative regulation of lipid biosynthetic process 1.788279e-3
GO:0051960 regulation of nervous system development 1.791127e-3
GO:0060479 lung cell differentiation 1.822130e-3
GO:0051438 regulation of ubiquitin-protein ligase activity 1.879467e-3
GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway 1.901730e-3
GO:0006413 translational initiation 1.903888e-3
GO:0048661 positive regulation of smooth muscle cell proliferation 1.916225e-3
GO:0051094 positive regulation of developmental process 1.948467e-3
GO:0001765 membrane raft assembly 1.977720e-3
GO:0034453 microtubule anchoring 1.980144e-3
GO:0014003 oligodendrocyte development 1.988892e-3
GO:0032774 RNA biosynthetic process 2.020745e-3
GO:0002070 epithelial cell maturation 2.028047e-3
GO:0048699 generation of neurons 2.054043e-3
GO:0045727 positive regulation of translation 2.093046e-3
GO:0022008 neurogenesis 2.095840e-3
GO:0032006 regulation of TOR signaling cascade 2.110888e-3
GO:0030177 positive regulation of Wnt receptor signaling pathway 2.118764e-3
GO:0007095 mitotic cell cycle G2/M transition DNA damage checkpoint 2.125203e-3
GO:0090138 regulation of actin cytoskeleton organization by cell-cell adhesion 2.147220e-3
GO:2000119 negative regulation of sodium-dependent phosphate transport 2.147220e-3
GO:0051882 mitochondrial depolarization 2.147220e-3
GO:0031860 telomeric 3' overhang formation 2.147220e-3
GO:0051657 maintenance of organelle location 2.195794e-3
GO:0060480 lung goblet cell differentiation 2.211234e-3
GO:0045964 positive regulation of dopamine metabolic process 2.211234e-3
GO:0016572 histone phosphorylation 2.221568e-3
GO:0010984 regulation of lipoprotein particle clearance 2.232674e-3
GO:0045950 negative regulation of mitotic recombination 2.249426e-3
GO:0048343 paraxial mesodermal cell fate commitment 2.249426e-3
GO:0051775 response to redox state 2.263604e-3
GO:0050717 positive regulation of interleukin-1 alpha secretion 2.263604e-3
GO:0022410 circadian sleep/wake cycle process 2.295241e-3
GO:0022403 cell cycle phase 2.321766e-3
GO:0007520 myoblast fusion 2.369273e-3
GO:0046425 regulation of JAK-STAT cascade 2.385041e-3
GO:0051340 regulation of ligase activity 2.388913e-3
GO:0006110 regulation of glycolysis 2.415579e-3
GO:0060215 primitive hemopoiesis 2.450929e-3
GO:0007051 spindle organization 2.523222e-3
GO:0060159 regulation of dopamine receptor signaling pathway 2.571608e-3
GO:0014013 regulation of gliogenesis 2.637716e-3
GO:2000761 positive regulation of N-terminal peptidyl-lysine acetylation 2.637721e-3
GO:0035910 ascending aorta morphogenesis 2.637721e-3
GO:0016446 somatic hypermutation of immunoglobulin genes 2.637721e-3
GO:0071841 cellular component organization or biogenesis at cellular level 2.674861e-3
GO:0001678 cellular glucose homeostasis 2.755683e-3
GO:0021953 central nervous system neuron differentiation 2.777590e-3
GO:0008542 visual learning 2.787086e-3
GO:0060638 mesenchymal-epithelial cell signaling 2.818287e-3
GO:2000286 receptor internalization involved in canonical Wnt receptor signaling pathway 2.843852e-3
GO:0051255 spindle midzone assembly 2.843852e-3
GO:0051899 membrane depolarization 2.887937e-3
GO:0007628 adult walking behavior 2.909342e-3
GO:0061002 negative regulation of dendritic spine morphogenesis 2.933915e-3
GO:0080125 multicellular structure septum development 2.974219e-3
GO:0070256 negative regulation of mucus secretion 2.974219e-3
GO:0060783 mesenchymal smoothened signaling pathway involved in prostate gland development 2.974219e-3
GO:2000063 positive regulation of ureter smooth muscle cell differentiation 2.974219e-3
GO:2000357 negative regulation of kidney smooth muscle cell differentiation 2.974219e-3
GO:2000358 positive regulation of kidney smooth muscle cell differentiation 2.974219e-3
GO:2000062 negative regulation of ureter smooth muscle cell differentiation 2.974219e-3
GO:0060782 regulation of mesenchymal cell proliferation involved in prostate gland development 2.974219e-3
GO:0007502 digestive tract mesoderm development 2.974219e-3
GO:0021526 medial motor column neuron differentiation 2.974219e-3
GO:0014858 positive regulation of skeletal muscle cell proliferation 2.974219e-3
GO:0046534 positive regulation of photoreceptor cell differentiation 2.974219e-3
GO:0042323 negative regulation of circadian sleep/wake cycle, non-REM sleep 2.974219e-3
GO:0007059 chromosome segregation 2.991310e-3
GO:0035270 endocrine system development 3.044808e-3
GO:0070373 negative regulation of ERK1 and ERK2 cascade 3.045150e-3
GO:0050679 positive regulation of epithelial cell proliferation 3.135266e-3
GO:0045685 regulation of glial cell differentiation 3.165945e-3
GO:0060525 prostate glandular acinus development 3.208915e-3
GO:0060516 primary prostatic bud elongation 3.226121e-3
GO:0072093 metanephric renal vesicle formation 3.226121e-3
GO:0032075 positive regulation of nuclease activity 3.226121e-3
GO:0046717 acid secretion 3.253370e-3
GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway 3.253370e-3
GO:0042053 regulation of dopamine metabolic process 3.280601e-3
GO:0002381 immunoglobulin production involved in immunoglobulin mediated immune response 3.292501e-3
GO:0060428 lung epithelium development 3.337500e-3
GO:0042745 circadian sleep/wake cycle 3.372308e-3
GO:0001945 lymph vessel development 3.372308e-3
GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity 3.416191e-3
GO:0043623 cellular protein complex assembly 3.505261e-3
GO:0021679 cerebellar molecular layer development 3.527697e-3
GO:0021750 vestibular nucleus development 3.527697e-3
GO:0021590 cerebellum maturation 3.527697e-3
GO:0010936 negative regulation of macrophage cytokine production 3.527697e-3
GO:0006548 histidine catabolic process 3.540231e-3
GO:0033345 asparagine catabolic process via L-aspartate 3.548325e-3
GO:0007060 male meiosis chromosome segregation 3.548325e-3
GO:0001986 negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure 3.548325e-3
GO:0042362 fat-soluble vitamin biosynthetic process 3.551603e-3
GO:2000602 regulation of interphase of mitotic cell cycle 3.617193e-3
GO:0051896 regulation of protein kinase B signaling cascade 3.617193e-3
GO:0007442 hindgut morphogenesis 3.623559e-3
GO:0014068 positive regulation of phosphatidylinositol 3-kinase cascade 3.657494e-3
GO:0031400 negative regulation of protein modification process 3.700866e-3
GO:0051054 positive regulation of DNA metabolic process 3.732421e-3
GO:0060556 regulation of vitamin D biosynthetic process 3.737165e-3
GO:2000465 regulation of glycogen (starch) synthase activity 3.764513e-3
GO:0060538 skeletal muscle organ development 3.801215e-3
GO:0090187 positive regulation of pancreatic juice secretion 3.820066e-3
GO:0090340 positive regulation of secretion of lysosomal enzymes 3.820066e-3
GO:0090108 positive regulation of high-density lipoprotein particle assembly 3.820066e-3
GO:0035087 siRNA loading onto RISC involved in RNA interference 3.820066e-3
GO:0031123 RNA 3'-end processing 3.820270e-3
GO:0048814 regulation of dendrite morphogenesis 3.840645e-3
GO:0045787 positive regulation of cell cycle 3.844252e-3
GO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis 3.855559e-3
GO:0045597 positive regulation of cell differentiation 3.868648e-3
GO:0050767 regulation of neurogenesis 3.908878e-3