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Novel motif:121

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name:motif121_TGCAWTGTA

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0046032 ADP catabolic process 1.376928e-16
GO:0046709 IDP catabolic process 1.376928e-16
GO:0032501 multicellular organismal process 1.020848e-15
GO:0009181 purine ribonucleoside diphosphate catabolic process 6.011790e-14
GO:0051606 detection of stimulus 2.026081e-13
GO:0016337 cell-cell adhesion 6.350196e-13
GO:0007208 activation of phospholipase C activity by serotonin receptor signaling pathway 8.408898e-13
GO:0048513 organ development 8.127035e-12
GO:0007155 cell adhesion 1.052215e-11
GO:0051179 localization 1.182261e-11
GO:0009191 ribonucleoside diphosphate catabolic process 1.945206e-11
GO:0065008 regulation of biological quality 6.366251e-11
GO:0090090 negative regulation of canonical Wnt receptor signaling pathway 7.024000e-11
GO:0051602 response to electrical stimulus 7.098922e-11
GO:0002376 immune system process 9.102573e-11
GO:0045666 positive regulation of neuron differentiation 1.508881e-10
GO:0050896 response to stimulus 1.794263e-10
GO:0006928 cellular component movement 1.935440e-10
GO:0009582 detection of abiotic stimulus 1.960641e-10
GO:0009611 response to wounding 2.311955e-10
GO:0048856 anatomical structure development 2.580254e-10
GO:0010038 response to metal ion 4.915576e-10
GO:0009888 tissue development 4.918556e-10
GO:0006953 acute-phase response 5.424383e-10
GO:0048731 system development 5.909890e-10
GO:0009581 detection of external stimulus 7.255502e-10
GO:0030178 negative regulation of Wnt receptor signaling pathway 1.128391e-9
GO:0050900 leukocyte migration 1.280175e-9
GO:0042060 wound healing 1.423870e-9
GO:0016477 cell migration 1.496131e-9
GO:0023057 negative regulation of signaling 1.506501e-9
GO:0010648 negative regulation of cell communication 1.588337e-9
GO:0045429 positive regulation of nitric oxide biosynthetic process 1.803122e-9
GO:0007611 learning or memory 1.857690e-9
GO:0032502 developmental process 2.259217e-9
GO:0045428 regulation of nitric oxide biosynthetic process 2.510965e-9
GO:0009653 anatomical structure morphogenesis 3.138939e-9
GO:0009607 response to biotic stimulus 3.139013e-9
GO:0009628 response to abiotic stimulus 3.793515e-9
GO:0006811 ion transport 4.215182e-9
GO:0009612 response to mechanical stimulus 4.246403e-9
GO:0007275 multicellular organismal development 4.298619e-9
GO:0050890 cognition 4.300189e-9
GO:0003008 system process 5.563296e-9
GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production 6.848174e-9
GO:0002526 acute inflammatory response 7.594232e-9
GO:0009617 response to bacterium 9.878527e-9
GO:0008228 opsonization 1.036017e-8
GO:0048518 positive regulation of biological process 1.447346e-8
GO:0010035 response to inorganic substance 1.484575e-8
GO:0006950 response to stress 2.058224e-8
GO:0006942 regulation of striated muscle contraction 2.232276e-8
GO:0007599 hemostasis 2.801115e-8
GO:0048870 cell motility 3.309873e-8
GO:0051707 response to other organism 3.547699e-8
GO:0060828 regulation of canonical Wnt receptor signaling pathway 3.586543e-8
GO:0007596 blood coagulation 3.814598e-8
GO:0007602 phototransduction 3.894000e-8
GO:0007610 behavior 4.294511e-8
GO:0050906 detection of stimulus involved in sensory perception 4.334283e-8
GO:0046031 ADP metabolic process 5.119355e-8
GO:0048869 cellular developmental process 5.279970e-8
GO:0050793 regulation of developmental process 6.171428e-8
GO:0032470 elevation of endoplasmic reticulum calcium ion concentration 8.574516e-8
GO:0090076 relaxation of skeletal muscle 8.574516e-8
GO:0010574 regulation of vascular endothelial growth factor production 9.334245e-8
GO:0040011 locomotion 9.389453e-8
GO:0032989 cellular component morphogenesis 9.651463e-8
GO:0050974 detection of mechanical stimulus involved in sensory perception 9.723852e-8
GO:0009179 purine ribonucleoside diphosphate metabolic process 1.241498e-7
GO:0006875 cellular metal ion homeostasis 1.305317e-7
GO:0009235 cobalamin metabolic process 1.346598e-7
GO:0008360 regulation of cell shape 1.400168e-7
GO:0044057 regulation of system process 1.680544e-7
GO:0030154 cell differentiation 1.879196e-7
GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production 2.058585e-7
GO:0010042 response to manganese ion 2.501465e-7
GO:0050982 detection of mechanical stimulus 2.560402e-7
GO:0007517 muscle organ development 2.794714e-7
GO:0048522 positive regulation of cellular process 2.868302e-7
GO:0009605 response to external stimulus 2.874904e-7
GO:0001558 regulation of cell growth 3.093894e-7
GO:0055065 metal ion homeostasis 3.144646e-7
GO:0009968 negative regulation of signal transduction 3.479884e-7
GO:0042221 response to chemical stimulus 3.536642e-7
GO:0050878 regulation of body fluid levels 3.679519e-7
GO:0065007 biological regulation 3.752863e-7
GO:0071287 cellular response to manganese ion 3.985383e-7
GO:0048583 regulation of response to stimulus 4.115709e-7
GO:0061024 membrane organization 4.307693e-7
GO:0030003 cellular cation homeostasis 4.325327e-7
GO:0048514 blood vessel morphogenesis 4.935352e-7
GO:0031946 regulation of glucocorticoid biosynthetic process 5.034835e-7
GO:0006810 transport 5.281725e-7
GO:0016044 cellular membrane organization 5.611655e-7
GO:0030301 cholesterol transport 5.774655e-7
GO:0015918 sterol transport 5.996300e-7
GO:0030111 regulation of Wnt receptor signaling pathway 6.022993e-7
GO:0014049 positive regulation of glutamate secretion 6.093527e-7
GO:0042418 epinephrine biosynthetic process 6.128915e-7
GO:0006585 dopamine biosynthetic process from tyrosine 6.128915e-7
GO:0072358 cardiovascular system development 6.968432e-7
GO:0048878 chemical homeostasis 7.198720e-7
GO:0052314 phytoalexin metabolic process 7.590143e-7
GO:0042127 regulation of cell proliferation 7.996912e-7
GO:0055082 cellular chemical homeostasis 8.332564e-7
GO:0051239 regulation of multicellular organismal process 8.407593e-7
GO:0051234 establishment of localization 8.675057e-7
GO:0015889 cobalamin transport 9.430576e-7
GO:0051047 positive regulation of secretion 1.047965e-6
GO:0014048 regulation of glutamate secretion 1.054826e-6
GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway 1.093499e-6
GO:0009185 ribonucleoside diphosphate metabolic process 1.113419e-6
GO:0001780 neutrophil homeostasis 1.113419e-6
GO:0072001 renal system development 1.120409e-6
GO:0051704 multi-organism process 1.164798e-6
GO:0048468 cell development 1.268992e-6
GO:0006542 glutamine biosynthetic process 1.483060e-6
GO:0030431 sleep 1.499472e-6
GO:0007613 memory 1.537163e-6
GO:0031448 positive regulation of fast-twitch skeletal muscle fiber contraction 1.688844e-6
GO:0002090 regulation of receptor internalization 1.706130e-6
GO:0072511 divalent inorganic cation transport 1.716706e-6
GO:0010646 regulation of cell communication 1.748801e-6
GO:0048646 anatomical structure formation involved in morphogenesis 1.868410e-6
GO:0015669 gas transport 2.001446e-6
GO:0042743 hydrogen peroxide metabolic process 2.025302e-6
GO:0042744 hydrogen peroxide catabolic process 2.053910e-6
GO:0001655 urogenital system development 2.242352e-6
GO:0090336 positive regulation of brown fat cell differentiation 2.267560e-6
GO:0090362 positive regulation of platelet-derived growth factor production 2.267560e-6
GO:0090271 positive regulation of fibroblast growth factor production 2.267560e-6
GO:0035845 photoreceptor cell outer segment organization 2.336161e-6
GO:0090287 regulation of cellular response to growth factor stimulus 2.549102e-6
GO:0001932 regulation of protein phosphorylation 2.558713e-6
GO:2000021 regulation of ion homeostasis 2.640068e-6
GO:0009583 detection of light stimulus 2.682536e-6
GO:0042325 regulation of phosphorylation 2.948256e-6
GO:0016192 vesicle-mediated transport 3.080578e-6
GO:0014823 response to activity 3.091817e-6
GO:0007210 serotonin receptor signaling pathway 3.106398e-6
GO:0055080 cation homeostasis 3.112469e-6
GO:0072503 cellular divalent inorganic cation homeostasis 3.162816e-6
GO:0006874 cellular calcium ion homeostasis 3.210122e-6
GO:0006873 cellular ion homeostasis 3.372219e-6
GO:0042414 epinephrine metabolic process 3.487565e-6
GO:0000902 cell morphogenesis 3.664643e-6
GO:0040008 regulation of growth 3.676735e-6
GO:0032496 response to lipopolysaccharide 3.722306e-6
GO:0033076 isoquinoline alkaloid metabolic process 3.789196e-6
GO:0007158 neuron cell-cell adhesion 3.811938e-6
GO:0045162 clustering of voltage-gated sodium channels 3.865949e-6
GO:0002237 response to molecule of bacterial origin 3.905766e-6
GO:0006816 calcium ion transport 4.113487e-6
GO:0046689 response to mercury ion 4.205374e-6
GO:0050910 detection of mechanical stimulus involved in sensory perception of sound 4.264753e-6
GO:0032846 positive regulation of homeostatic process 4.355150e-6
GO:0043402 glucocorticoid mediated signaling pathway 4.498714e-6
GO:0015671 oxygen transport 4.609639e-6
GO:0035176 social behavior 4.724383e-6
GO:0006812 cation transport 4.790024e-6
GO:0019725 cellular homeostasis 4.807748e-6
GO:0045410 positive regulation of interleukin-6 biosynthetic process 4.979558e-6
GO:0055074 calcium ion homeostasis 4.981777e-6
GO:0019220 regulation of phosphate metabolic process 5.056794e-6
GO:0006959 humoral immune response 5.280841e-6
GO:0071840 cellular component organization or biogenesis 5.367376e-6
GO:0001822 kidney development 5.480958e-6
GO:0050966 detection of mechanical stimulus involved in sensory perception of pain 5.655816e-6
GO:0010575 positive regulation vascular endothelial growth factor production 5.778789e-6
GO:0007612 learning 5.784240e-6
GO:0003007 heart morphogenesis 5.863908e-6
GO:0019233 sensory perception of pain 6.059676e-6
GO:0048585 negative regulation of response to stimulus 6.068104e-6
GO:0030728 ovulation 6.298790e-6
GO:0030185 nitric oxide transport 6.702246e-6
GO:0050789 regulation of biological process 6.747129e-6
GO:0016043 cellular component organization 7.102767e-6
GO:0001659 temperature homeostasis 7.394679e-6
GO:0008038 neuron recognition 7.543710e-6
GO:0050801 ion homeostasis 7.656869e-6
GO:0006952 defense response 7.747852e-6
GO:0030001 metal ion transport 8.206717e-6
GO:0072507 divalent inorganic cation homeostasis 8.964363e-6
GO:0051967 negative regulation of synaptic transmission, glutamatergic 9.064486e-6
GO:0032770 positive regulation of monooxygenase activity 9.562818e-6
GO:0007166 cell surface receptor linked signaling pathway 9.683650e-6
GO:0032879 regulation of localization 9.721910e-6
GO:0019227 neuronal action potential propagation 9.970271e-6
GO:0045161 neuronal ion channel clustering 1.013713e-5
GO:0010822 positive regulation of mitochondrion organization 1.013713e-5
GO:0034614 cellular response to reactive oxygen species 1.043700e-5
GO:0006954 inflammatory response 1.067031e-5
GO:0010883 regulation of lipid storage 1.091683e-5
GO:0051142 positive regulation of NK T cell proliferation 1.151440e-5
GO:0002711 positive regulation of T cell mediated immunity 1.212255e-5
GO:0042214 terpene metabolic process 1.212879e-5
GO:0010350 cellular response to magnesium starvation 1.235643e-5
GO:0022603 regulation of anatomical structure morphogenesis 1.258594e-5
GO:0061061 muscle structure development 1.271805e-5
GO:0003308 negative regulation of Wnt receptor signaling pathway involved in heart development 1.292513e-5
GO:0002092 positive regulation of receptor internalization 1.330009e-5
GO:0001568 blood vessel development 1.340221e-5
GO:0060537 muscle tissue development 1.360463e-5
GO:0006897 endocytosis 1.398778e-5
GO:0043380 regulation of memory T cell differentiation 1.467137e-5
GO:0031622 positive regulation of fever generation 1.491838e-5
GO:0050911 detection of chemical stimulus involved in sensory perception of smell 1.494629e-5
GO:0048169 regulation of long-term neuronal synaptic plasticity 1.533149e-5
GO:0031341 regulation of cell killing 1.537918e-5
GO:0023052 signaling 1.548817e-5
GO:0031943 regulation of glucocorticoid metabolic process 1.616433e-5
GO:0001910 regulation of leukocyte mediated cytotoxicity 1.618904e-5
GO:0090270 regulation of fibroblast growth factor production 1.629528e-5
GO:0001944 vasculature development 1.762645e-5
GO:0002709 regulation of T cell mediated immunity 1.796917e-5
GO:0009966 regulation of signal transduction 1.822718e-5
GO:0071320 cellular response to cAMP 1.825323e-5
GO:0051966 regulation of synaptic transmission, glutamatergic 1.889700e-5
GO:0051716 cellular response to stimulus 1.990047e-5
GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly 2.010232e-5
GO:0042592 homeostatic process 2.066103e-5
GO:0071396 cellular response to lipid 2.066853e-5
GO:0030325 adrenal gland development 2.077824e-5
GO:0031645 negative regulation of neurological system process 2.099686e-5
GO:0002706 regulation of lymphocyte mediated immunity 2.107497e-5
GO:0048769 sarcomerogenesis 2.118394e-5
GO:0016339 calcium-dependent cell-cell adhesion 2.197817e-5
GO:0009593 detection of chemical stimulus 2.239837e-5
GO:0032844 regulation of homeostatic process 2.277671e-5
GO:0009408 response to heat 2.300355e-5
GO:0034374 low-density lipoprotein particle remodeling 2.353926e-5
GO:0048729 tissue morphogenesis 2.362729e-5
GO:0070838 divalent metal ion transport 2.473091e-5
GO:0014842 regulation of satellite cell proliferation 2.577702e-5
GO:0031652 positive regulation of heat generation 2.603571e-5
GO:0048519 negative regulation of biological process 2.658452e-5
GO:0048853 forebrain morphogenesis 2.663776e-5
GO:0007157 heterophilic cell-cell adhesion 2.667465e-5
GO:0050907 detection of chemical stimulus involved in sensory perception 2.736792e-5
GO:0007165 signal transduction 2.817037e-5
GO:0051209 release of sequestered calcium ion into cytosol 2.887759e-5
GO:0042632 cholesterol homeostasis 2.898543e-5
GO:0031394 positive regulation of prostaglandin biosynthetic process 2.956319e-5
GO:0006937 regulation of muscle contraction 3.093187e-5
GO:0070301 cellular response to hydrogen peroxide 3.140745e-5
GO:0006781 succinyl-CoA pathway 3.174160e-5
GO:0050671 positive regulation of lymphocyte proliferation 3.322062e-5
GO:0018149 peptide cross-linking 3.373190e-5
GO:0060538 skeletal muscle organ development 3.373720e-5
GO:0051969 regulation of transmission of nerve impulse 3.393745e-5
GO:0009132 nucleoside diphosphate metabolic process 3.411099e-5
GO:0045765 regulation of angiogenesis 3.428118e-5
GO:0032768 regulation of monooxygenase activity 3.455845e-5
GO:0055003 cardiac myofibril assembly 3.589140e-5
GO:0008285 negative regulation of cell proliferation 3.679205e-5
GO:0014889 muscle atrophy 3.731653e-5
GO:0051384 response to glucocorticoid stimulus 3.774840e-5
GO:0032621 interleukin-18 production 3.798903e-5
GO:0002252 immune effector process 3.851780e-5
GO:0006958 complement activation, classical pathway 3.853763e-5
GO:0043408 regulation of MAPKKK cascade 3.879737e-5
GO:0072376 protein activation cascade 3.942599e-5
GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway 3.963502e-5
GO:0031644 regulation of neurological system process 3.982608e-5
GO:0003307 regulation of Wnt receptor signaling pathway involved in heart development 4.082867e-5
GO:0001775 cell activation 4.193265e-5
GO:0007156 homophilic cell adhesion 4.281283e-5
GO:0051282 regulation of sequestering of calcium ion 4.452878e-5
GO:0050870 positive regulation of T cell activation 4.454095e-5
GO:0051970 negative regulation of transmission of nerve impulse 4.475708e-5
GO:0009887 organ morphogenesis 4.825587e-5
GO:0045472 response to ether 4.855613e-5
GO:0034373 intermediate-density lipoprotein particle remodeling 5.012153e-5
GO:0034599 cellular response to oxidative stress 5.100787e-5
GO:0048643 positive regulation of skeletal muscle tissue development 5.319736e-5
GO:0032819 positive regulation of natural killer cell proliferation 5.437489e-5
GO:0032924 activin receptor signaling pathway 5.500368e-5
GO:0009306 protein secretion 5.532761e-5
GO:0051341 regulation of oxidoreductase activity 5.601264e-5
GO:0071248 cellular response to metal ion 5.714414e-5
GO:0051353 positive regulation of oxidoreductase activity 5.774298e-5
GO:0010942 positive regulation of cell death 5.873135e-5
GO:0032946 positive regulation of mononuclear cell proliferation 6.197098e-5
GO:0015722 canalicular bile acid transport 6.543789e-5
GO:0006824 cobalt ion transport 6.638525e-5
GO:0042178 xenobiotic catabolic process 6.833151e-5
GO:0014706 striated muscle tissue development 6.839805e-5
GO:0001525 angiogenesis 6.898280e-5
GO:0050810 regulation of steroid biosynthetic process 6.964776e-5
GO:0030240 skeletal muscle thin filament assembly 7.013682e-5
GO:0007154 cell communication 7.016739e-5
GO:0060559 positive regulation of calcidiol 1-monooxygenase activity 7.107581e-5
GO:0006111 regulation of gluconeogenesis 7.176830e-5
GO:0051251 positive regulation of lymphocyte activation 7.182046e-5
GO:0023051 regulation of signaling 7.327401e-5
GO:0070509 calcium ion import 7.409580e-5
GO:0030241 skeletal muscle myosin thick filament assembly 7.634583e-5
GO:0043409 negative regulation of MAPKKK cascade 7.668594e-5
GO:0090257 regulation of muscle system process 7.799592e-5
GO:0019216 regulation of lipid metabolic process 7.810598e-5
GO:0008037 cell recognition 7.823016e-5
GO:0070286 axonemal dynein complex assembly 7.984742e-5
GO:0071241 cellular response to inorganic substance 8.134227e-5
GO:0071286 cellular response to magnesium ion 8.138736e-5
GO:0006956 complement activation 8.152609e-5
GO:0015855 pyrimidine base transport 8.278279e-5
GO:0034638 phosphatidylcholine catabolic process 8.567910e-5
GO:0000904 cell morphogenesis involved in differentiation 8.734696e-5
GO:0046649 lymphocyte activation 9.000455e-5
GO:0035037 sperm entry 9.092330e-5
GO:0055013 cardiac muscle cell development 9.100255e-5
GO:0010743 regulation of macrophage derived foam cell differentiation 9.129641e-5
GO:0021509 roof plate formation 9.131483e-5
GO:0001781 neutrophil apoptosis 9.183675e-5
GO:0032817 regulation of natural killer cell proliferation 9.353299e-5
GO:0046903 secretion 9.409604e-5
GO:2000026 regulation of multicellular organismal development 9.485701e-5
GO:0034105 positive regulation of tissue remodeling 9.506433e-5
GO:0010886 positive regulation of cholesterol storage 9.582830e-5
GO:0006066 alcohol metabolic process 9.717668e-5
GO:0070164 negative regulation of adiponectin secretion 9.895329e-5
GO:0035505 positive regulation of myosin light chain kinase activity 9.895329e-5
GO:0060355 positive regulation of cell adhesion molecule production 9.895329e-5
GO:0051050 positive regulation of transport 9.904066e-5
GO:0051128 regulation of cellular component organization 9.913858e-5
GO:0042102 positive regulation of T cell proliferation 1.000575e-4
GO:0002262 myeloid cell homeostasis 1.013766e-4
GO:0060807 regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification 1.022624e-4
GO:0003142 cardiogenic plate morphogenesis 1.022624e-4
GO:0015842 synaptic vesicle amine transport 1.022624e-4
GO:0051131 chaperone-mediated protein complex assembly 1.046709e-4
GO:0050794 regulation of cellular process 1.060818e-4
GO:0002769 natural killer cell inhibitory signaling pathway 1.086148e-4
GO:0045769 negative regulation of asymmetric cell division 1.086148e-4
GO:0051272 positive regulation of cellular component movement 1.121098e-4
GO:0051960 regulation of nervous system development 1.133061e-4
GO:0046885 regulation of hormone biosynthetic process 1.181191e-4
GO:0050776 regulation of immune response 1.203073e-4
GO:0033552 response to vitamin B3 1.208683e-4
GO:0007267 cell-cell signaling 1.237679e-4
GO:0051657 maintenance of organelle location 1.252909e-4
GO:0001816 cytokine production 1.277832e-4
GO:0032940 secretion by cell 1.288406e-4
GO:0034381 plasma lipoprotein particle clearance 1.294951e-4
GO:0046329 negative regulation of JNK cascade 1.307057e-4
GO:0040017 positive regulation of locomotion 1.376952e-4
GO:0010817 regulation of hormone levels 1.397751e-4
GO:0008284 positive regulation of cell proliferation 1.410841e-4
GO:0055088 lipid homeostasis 1.428148e-4
GO:0061031 endodermal digestive tract morphogenesis 1.447813e-4
GO:0070163 regulation of adiponectin secretion 1.460450e-4
GO:0009987 cellular process 1.490706e-4
GO:0071639 positive regulation of monocyte chemotactic protein-1 production 1.503595e-4
GO:0090361 regulation of platelet-derived growth factor production 1.529906e-4
GO:0051561 elevation of mitochondrial calcium ion concentration 1.575852e-4
GO:0007600 sensory perception 1.598610e-4
GO:0030900 forebrain development 1.611599e-4
GO:0045893 positive regulation of transcription, DNA-dependent 1.627819e-4
GO:0043549 regulation of kinase activity 1.648480e-4
GO:0007631 feeding behavior 1.653495e-4
GO:0043407 negative regulation of MAP kinase activity 1.725843e-4
GO:0015825 L-serine transport 1.730806e-4
GO:0048854 brain morphogenesis 1.759725e-4
GO:0090149 membrane fission involved in mitochondrial fission 1.764960e-4
GO:0003374 dynamin polymerization involved in mitochondrial fission 1.764960e-4
GO:0051705 behavioral interaction between organisms 1.765434e-4
GO:0051093 negative regulation of developmental process 1.773985e-4
GO:0050867 positive regulation of cell activation 1.796040e-4
GO:0019371 cyclooxygenase pathway 1.817690e-4
GO:0050877 neurological system process 1.817757e-4
GO:0001947 heart looping 1.823372e-4
GO:0030518 steroid hormone receptor signaling pathway 1.831725e-4
GO:0070665 positive regulation of leukocyte proliferation 1.849152e-4
GO:0019835 cytolysis 1.856155e-4
GO:0051592 response to calcium ion 1.869355e-4
GO:0016140 O-glycoside metabolic process 1.870378e-4
GO:0045907 positive regulation of vasoconstriction 1.871656e-4
GO:0048634 regulation of muscle organ development 1.885966e-4
GO:0043933 macromolecular complex subunit organization 1.892637e-4
GO:0045597 positive regulation of cell differentiation 1.921835e-4
GO:0090200 positive regulation of release of cytochrome c from mitochondria 1.981644e-4
GO:0048096 chromatin-mediated maintenance of transcription 1.995771e-4
GO:0007586 digestion 2.002096e-4
GO:0060438 trachea development 2.011099e-4
GO:0050805 negative regulation of synaptic transmission 2.027080e-4
GO:0090129 positive regulation of synapse maturation 2.052695e-4
GO:0050918 positive chemotaxis 2.061783e-4
GO:0010821 regulation of mitochondrion organization 2.092917e-4
GO:0009743 response to carbohydrate stimulus 2.145750e-4
GO:0050863 regulation of T cell activation 2.171550e-4
GO:0002455 humoral immune response mediated by circulating immunoglobulin 2.197471e-4
GO:0009266 response to temperature stimulus 2.203208e-4
GO:0043267 negative regulation of potassium ion transport 2.233768e-4
GO:0032874 positive regulation of stress-activated MAPK cascade 2.265469e-4
GO:0007076 mitotic chromosome condensation 2.319520e-4
GO:0045844 positive regulation of striated muscle tissue development 2.347574e-4
GO:0007204 elevation of cytosolic calcium ion concentration 2.420695e-4
GO:0007608 sensory perception of smell 2.440489e-4
GO:0010628 positive regulation of gene expression 2.465936e-4
GO:0048660 regulation of smooth muscle cell proliferation 2.497684e-4
GO:0033280 response to vitamin D 2.572775e-4
GO:0071901 negative regulation of protein serine/threonine kinase activity 2.661222e-4
GO:0001890 placenta development 2.661683e-4
GO:0042346 positive regulation of NF-kappaB import into nucleus 2.679409e-4
GO:0045408 regulation of interleukin-6 biosynthetic process 2.689136e-4
GO:0043525 positive regulation of neuron apoptosis 2.731197e-4
GO:0048245 eosinophil chemotaxis 2.732182e-4
GO:0045859 regulation of protein kinase activity 2.755252e-4
GO:0002251 organ or tissue specific immune response 2.819122e-4
GO:0002708 positive regulation of lymphocyte mediated immunity 2.858872e-4
GO:0050803 regulation of synapse structure and activity 2.889419e-4
GO:0042953 lipoprotein transport 2.901322e-4
GO:2000095 regulation of Wnt receptor signaling pathway, planar cell polarity pathway 2.931585e-4
GO:0007519 skeletal muscle tissue development 3.066864e-4
GO:0071705 nitrogen compound transport 3.099948e-4
GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity 3.108770e-4
GO:0090082 positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway 3.109558e-4
GO:0007368 determination of left/right symmetry 3.111609e-4
GO:0071637 regulation of monocyte chemotactic protein-1 production 3.126197e-4
GO:0002696 positive regulation of leukocyte activation 3.131803e-4
GO:0009566 fertilization 3.173052e-4
GO:0045664 regulation of neuron differentiation 3.248237e-4
GO:0070887 cellular response to chemical stimulus 3.264101e-4
GO:0032835 glomerulus development 3.269633e-4
GO:0014059 regulation of dopamine secretion 3.288552e-4
GO:0090128 regulation of synapse maturation 3.356680e-4
GO:0031536 positive regulation of exit from mitosis 3.356680e-4
GO:0007160 cell-matrix adhesion 3.370236e-4
GO:0070588 calcium ion transmembrane transport 3.537825e-4
GO:0050718 positive regulation of interleukin-1 beta secretion 3.553836e-4
GO:0032872 regulation of stress-activated MAPK cascade 3.558262e-4
GO:0051173 positive regulation of nitrogen compound metabolic process 3.587891e-4
GO:0030097 hemopoiesis 3.670433e-4
GO:0043113 receptor clustering 3.748883e-4
GO:0046486 glycerolipid metabolic process 3.752900e-4
GO:0046549 retinal cone cell development 3.777898e-4
GO:0097091 synaptic vesicle clustering 3.803012e-4
GO:0001706 endoderm formation 3.818792e-4
GO:0032026 response to magnesium ion 3.831690e-4
GO:0046890 regulation of lipid biosynthetic process 3.879105e-4
GO:0051258 protein polymerization 3.955566e-4
GO:0006935 chemotaxis 3.955785e-4
GO:0014866 skeletal myofibril assembly 3.962565e-4
GO:0022607 cellular component assembly 3.969061e-4
GO:0007413 axonal fasciculation 4.014983e-4
GO:0009314 response to radiation 4.043155e-4
GO:0015851 nucleobase transport 4.070583e-4
GO:0051480 cytosolic calcium ion homeostasis 4.119569e-4
GO:0001831 trophectodermal cellular morphogenesis 4.149265e-4
GO:0034369 plasma lipoprotein particle remodeling 4.151952e-4
GO:0034372 very-low-density lipoprotein particle remodeling 4.198393e-4
GO:0010565 regulation of cellular ketone metabolic process 4.205538e-4
GO:0044060 regulation of endocrine process 4.268521e-4
GO:0001696 gastric acid secretion 4.271401e-4
GO:0042129 regulation of T cell proliferation 4.278516e-4
GO:0008544 epidermis development 4.473779e-4
GO:0097114 N-methyl-D-aspartate receptor clustering 4.503889e-4
GO:0097112 gamma-aminobutyric acid receptor clustering 4.503889e-4
GO:0097117 guanylate kinase-associated protein clustering 4.503889e-4
GO:0032227 negative regulation of synaptic transmission, dopaminergic 4.503889e-4
GO:0014819 regulation of skeletal muscle contraction 4.503889e-4
GO:0001666 response to hypoxia 4.516138e-4
GO:0042921 glucocorticoid receptor signaling pathway 4.541286e-4
GO:0046716 muscle cell homeostasis 4.547396e-4
GO:0070303 negative regulation of stress-activated protein kinase signaling cascade 4.617685e-4
GO:0071827 plasma lipoprotein particle organization 4.650366e-4
GO:0003018 vascular process in circulatory system 4.693232e-4
GO:0031589 cell-substrate adhesion 4.724809e-4
GO:0043266 regulation of potassium ion transport 4.748305e-4
GO:0034446 substrate adhesion-dependent cell spreading 4.790847e-4
GO:0050670 regulation of lymphocyte proliferation 4.866302e-4
GO:0051180 vitamin transport 4.916382e-4
GO:0030182 neuron differentiation 5.007817e-4
GO:0030030 cell projection organization 5.132755e-4
GO:0015833 peptide transport 5.139999e-4
GO:0006661 phosphatidylinositol biosynthetic process 5.181276e-4
GO:0001660 fever generation 5.246802e-4
GO:0042307 positive regulation of protein import into nucleus 5.325849e-4
GO:0051823 regulation of synapse structural plasticity 5.449763e-4
GO:0051338 regulation of transferase activity 5.487215e-4
GO:0045723 positive regulation of fatty acid biosynthetic process 5.521299e-4
GO:0007417 central nervous system development 5.533225e-4
GO:0048584 positive regulation of response to stimulus 5.554938e-4
GO:0034201 response to oleic acid 5.565213e-4
GO:0030335 positive regulation of cell migration 5.576671e-4
GO:0042990 regulation of transcription factor import into nucleus 5.613257e-4
GO:0043116 negative regulation of vascular permeability 5.635879e-4
GO:0042345 regulation of NF-kappaB import into nucleus 5.697137e-4
GO:0032329 serine transport 5.794153e-4
GO:0031328 positive regulation of cellular biosynthetic process 5.822734e-4
GO:0030029 actin filament-based process 5.825398e-4
GO:0008104 protein localization 5.874473e-4
GO:0060562 epithelial tube morphogenesis 6.081435e-4
GO:0031960 response to corticosteroid stimulus 6.130322e-4
GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 6.131554e-4
GO:0034605 cellular response to heat 6.139271e-4
GO:0097006 regulation of plasma lipoprotein particle levels 6.195421e-4
GO:0007568 aging 6.250425e-4
GO:0015791 polyol transport 6.251683e-4


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0010591 regulation of lamellipodium assembly 1.329987e-9
GO:0045919 positive regulation of cytolysis 2.988867e-9
GO:0043519 regulation of myosin II filament organization 1.272751e-8
GO:0005980 glycogen catabolic process 2.033842e-8
GO:0060491 regulation of cell projection assembly 3.969690e-8
GO:0032956 regulation of actin cytoskeleton organization 6.561636e-8
GO:0032970 regulation of actin filament-based process 1.067931e-7
GO:0060998 regulation of dendritic spine development 2.294354e-7
GO:0043380 regulation of memory T cell differentiation 2.883031e-7
GO:0032185 septin cytoskeleton organization 3.535880e-7
GO:0006950 response to stress 4.697189e-7
GO:0035024 negative regulation of Rho protein signal transduction 4.988191e-7
GO:0010592 positive regulation of lamellipodium assembly 5.780448e-7
GO:0009605 response to external stimulus 6.824261e-7
GO:0032764 negative regulation of mast cell cytokine production 7.537905e-7
GO:0048294 negative regulation of isotype switching to IgE isotypes 9.358093e-7
GO:0045321 leukocyte activation 1.171495e-6
GO:0048293 regulation of isotype switching to IgE isotypes 1.637194e-6
GO:0006108 malate metabolic process 2.078179e-6
GO:0042092 type 2 immune response 2.466172e-6
GO:0022604 regulation of cell morphogenesis 2.841141e-6
GO:0009225 nucleotide-sugar metabolic process 2.946280e-6
GO:0000272 polysaccharide catabolic process 3.060800e-6
GO:0015876 acetyl-CoA transport 3.214517e-6
GO:0006810 transport 3.452516e-6
GO:0046395 carboxylic acid catabolic process 3.453634e-6
GO:0042769 DNA damage response, detection of DNA damage 3.632365e-6
GO:0051606 detection of stimulus 4.073292e-6
GO:0050793 regulation of developmental process 4.477558e-6
GO:0000902 cell morphogenesis 4.663896e-6
GO:0048858 cell projection morphogenesis 5.010845e-6
GO:0044282 small molecule catabolic process 5.275302e-6
GO:0030832 regulation of actin filament length 6.078567e-6
GO:0010638 positive regulation of organelle organization 6.141218e-6
GO:0002829 negative regulation of type 2 immune response 6.393989e-6
GO:0045620 negative regulation of lymphocyte differentiation 6.454294e-6
GO:0009063 cellular amino acid catabolic process 6.455114e-6
GO:0051234 establishment of localization 6.710766e-6
GO:0008064 regulation of actin polymerization or depolymerization 7.124148e-6
GO:0050896 response to stimulus 7.132660e-6
GO:0045629 negative regulation of T-helper 2 cell differentiation 7.414804e-6
GO:0032990 cell part morphogenesis 7.629961e-6
GO:0031667 response to nutrient levels 7.974919e-6
GO:0051491 positive regulation of filopodium assembly 8.170600e-6
GO:0044087 regulation of cellular component biogenesis 8.213794e-6
GO:0090276 regulation of peptide hormone secretion 8.306935e-6
GO:0023061 signal release 8.453252e-6
GO:0007584 response to nutrient 9.080839e-6
GO:0031344 regulation of cell projection organization 1.080345e-5
GO:0046826 negative regulation of protein export from nucleus 1.081767e-5
GO:0000103 sulfate assimilation 1.081767e-5
GO:0046639 negative regulation of alpha-beta T cell differentiation 1.095206e-5
GO:0009991 response to extracellular stimulus 1.144631e-5
GO:0051901 positive regulation of mitochondrial depolarization 1.251089e-5
GO:0032763 regulation of mast cell cytokine production 1.251089e-5
GO:0060271 cilium morphogenesis 1.293475e-5
GO:0046649 lymphocyte activation 1.293494e-5
GO:0002791 regulation of peptide secretion 1.333784e-5
GO:0001775 cell activation 1.337057e-5
GO:0046381 CMP-N-acetylneuraminate metabolic process 1.459713e-5
GO:0033043 regulation of organelle organization 1.561763e-5
GO:0060828 regulation of canonical Wnt receptor signaling pathway 1.603444e-5
GO:0065008 regulation of biological quality 1.642202e-5
GO:0007089 traversing start control point of mitotic cell cycle 1.677026e-5
GO:0007596 blood coagulation 1.725838e-5
GO:0048731 system development 1.772764e-5
GO:0030838 positive regulation of actin filament polymerization 1.825852e-5
GO:0051058 negative regulation of small GTPase mediated signal transduction 1.843029e-5
GO:0046587 positive regulation of calcium-dependent cell-cell adhesion 1.868979e-5
GO:0007599 hemostasis 2.057945e-5
GO:0010942 positive regulation of cell death 2.094885e-5
GO:0051046 regulation of secretion 2.121417e-5
GO:0045623 negative regulation of T-helper cell differentiation 2.217898e-5
GO:0006040 amino sugar metabolic process 2.234431e-5
GO:0051179 localization 2.324844e-5
GO:0007040 lysosome organization 2.453541e-5
GO:0030890 positive regulation of B cell proliferation 2.484215e-5
GO:0045619 regulation of lymphocyte differentiation 2.517169e-5
GO:0003183 mitral valve morphogenesis 2.704447e-5
GO:0007050 cell cycle arrest 2.783496e-5
GO:0043584 nose development 2.789211e-5
GO:0051493 regulation of cytoskeleton organization 2.799792e-5
GO:0071773 cellular response to BMP stimulus 2.846908e-5
GO:0044262 cellular carbohydrate metabolic process 3.008245e-5
GO:0046580 negative regulation of Ras protein signal transduction 3.029253e-5
GO:0061001 regulation of dendritic spine morphogenesis 3.042161e-5
GO:0021522 spinal cord motor neuron differentiation 3.342345e-5
GO:0045622 regulation of T-helper cell differentiation 3.567873e-5
GO:0006054 N-acetylneuraminate metabolic process 3.608911e-5
GO:0005975 carbohydrate metabolic process 3.722433e-5
GO:0071504 cellular response to heparin 3.945135e-5
GO:0051128 regulation of cellular component organization 4.395835e-5
GO:0048814 regulation of dendrite morphogenesis 4.490164e-5
GO:0061002 negative regulation of dendritic spine morphogenesis 4.605043e-5
GO:2000515 negative regulation of CD4-positive, alpha-beta T cell activation 4.730860e-5
GO:0006605 protein targeting 4.877584e-5
GO:0008360 regulation of cell shape 5.028671e-5
GO:0071503 response to heparin 5.114442e-5
GO:0030030 cell projection organization 5.421642e-5
GO:0043068 positive regulation of programmed cell death 5.487300e-5
GO:0019543 propionate catabolic process 5.609447e-5
GO:0050773 regulation of dendrite development 5.717174e-5
GO:0035567 non-canonical Wnt receptor signaling pathway 5.759161e-5
GO:0018105 peptidyl-serine phosphorylation 5.827606e-5
GO:0034695 response to prostaglandin E stimulus 6.381396e-5
GO:0042119 neutrophil activation 6.381396e-5
GO:0061301 cerebellum vasculature morphogenesis 6.556143e-5
GO:0051495 positive regulation of cytoskeleton organization 6.916760e-5
GO:0042268 regulation of cytolysis 6.972243e-5
GO:0055074 calcium ion homeostasis 7.432054e-5
GO:0046636 negative regulation of alpha-beta T cell activation 7.667355e-5
GO:0050671 positive regulation of lymphocyte proliferation 7.844906e-5
GO:0008285 negative regulation of cell proliferation 8.461708e-5
GO:0048699 generation of neurons 8.584221e-5
GO:0046883 regulation of hormone secretion 8.585351e-5
GO:0030182 neuron differentiation 9.101056e-5
GO:2000756 regulation of peptidyl-lysine acetylation 9.178798e-5
GO:0017157 regulation of exocytosis 9.216852e-5
GO:0005996 monosaccharide metabolic process 9.258568e-5
GO:2000080 negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation 9.292479e-5
GO:2000271 positive regulation of fibroblast apoptosis 9.292479e-5
GO:0070627 ferrous iron import 9.292479e-5
GO:2000270 negative regulation of fibroblast apoptosis 9.292479e-5
GO:0015676 vanadium ion transport 9.292479e-5
GO:0015692 lead ion transport 9.292479e-5
GO:0044345 stromal-epithelial cell signaling involved in prostate gland development 9.292479e-5
GO:0010025 wax biosynthetic process 9.331950e-5
GO:0032946 positive regulation of mononuclear cell proliferation 9.477193e-5
GO:0043434 response to peptide hormone stimulus 9.477990e-5
GO:0022008 neurogenesis 9.569187e-5
GO:0051900 regulation of mitochondrial depolarization 9.758249e-5
GO:0051489 regulation of filopodium assembly 1.017424e-4
GO:0046825 regulation of protein export from nucleus 1.019333e-4
GO:0045595 regulation of cell differentiation 1.080000e-4
GO:0009310 amine catabolic process 1.087044e-4
GO:0051899 membrane depolarization 1.089700e-4
GO:0070665 positive regulation of leukocyte proliferation 1.095569e-4
GO:0043065 positive regulation of apoptosis 1.118417e-4
GO:0030111 regulation of Wnt receptor signaling pathway 1.121427e-4
GO:0018209 peptidyl-serine modification 1.144088e-4
GO:0019541 propionate metabolic process 1.181382e-4
GO:0001522 pseudouridine synthesis 1.195286e-4
GO:0060123 regulation of growth hormone secretion 1.210534e-4
GO:2000079 regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation 1.282815e-4
GO:0071380 cellular response to prostaglandin E stimulus 1.282815e-4
GO:0060341 regulation of cellular localization 1.397653e-4
GO:0060041 retina development in camera-type eye 1.425715e-4
GO:0045580 regulation of T cell differentiation 1.444133e-4
GO:0033144 negative regulation of steroid hormone receptor signaling pathway 1.582701e-4
GO:0097115 neurexin clustering 1.724694e-4
GO:0055065 metal ion homeostasis 1.734543e-4
GO:0044275 cellular carbohydrate catabolic process 1.790656e-4
GO:0006886 intracellular protein transport 1.811851e-4
GO:0046637 regulation of alpha-beta T cell differentiation 1.836047e-4
GO:0007033 vacuole organization 1.918462e-4
GO:0071305 cellular response to vitamin D 1.956251e-4
GO:0043113 receptor clustering 2.103113e-4
GO:0090090 negative regulation of canonical Wnt receptor signaling pathway 2.137329e-4
GO:0034694 response to prostaglandin stimulus 2.161828e-4
GO:0007158 neuron cell-cell adhesion 2.205651e-4
GO:0046677 response to antibiotic 2.248807e-4
GO:0016476 regulation of embryonic cell shape 2.251165e-4
GO:0072507 divalent inorganic cation homeostasis 2.323398e-4
GO:0002719 negative regulation of cytokine production involved in immune response 2.324045e-4
GO:0051053 negative regulation of DNA metabolic process 2.400859e-4
GO:0006066 alcohol metabolic process 2.413600e-4
GO:0032501 multicellular organismal process 2.455506e-4
GO:0034435 cholesterol esterification 2.473626e-4
GO:0021543 pallium development 2.485862e-4
GO:0010975 regulation of neuron projection development 2.490025e-4
GO:0006479 protein methylation 2.559973e-4
GO:0045581 negative regulation of T cell differentiation 2.628783e-4
GO:0005978 glycogen biosynthetic process 2.647727e-4
GO:0050775 positive regulation of dendrite morphogenesis 2.716358e-4
GO:0045910 negative regulation of DNA recombination 2.716358e-4
GO:0016052 carbohydrate catabolic process 2.728542e-4
GO:0051927 negative regulation of calcium ion transport via voltage-gated calcium channel activity 2.737415e-4
GO:0072643 interferon-gamma secretion 2.826175e-4
GO:0072608 interleukin-10 secretion 2.826175e-4
GO:0090198 negative regulation of chemokine secretion 2.826175e-4
GO:0043311 positive regulation of eosinophil degranulation 2.826175e-4
GO:0035926 chemokine (C-C motif) ligand 2 secretion 2.826175e-4
GO:0070963 positive regulation of neutrophil mediated killing of gram-negative bacterium 2.826175e-4
GO:0048856 anatomical structure development 2.885271e-4
GO:0050864 regulation of B cell activation 3.262947e-4
GO:0045664 regulation of neuron differentiation 3.296092e-4
GO:0009083 branched chain family amino acid catabolic process 3.302551e-4
GO:0072657 protein localization in membrane 3.401783e-4
GO:0007399 nervous system development 3.449141e-4
GO:0033674 positive regulation of kinase activity 3.460775e-4
GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway 3.804593e-4
GO:0032319 regulation of Rho GTPase activity 3.847165e-4
GO:0016042 lipid catabolic process 3.850255e-4
GO:0021537 telencephalon development 3.874623e-4
GO:0048878 chemical homeostasis 3.884843e-4
GO:0051182 coenzyme transport 3.966881e-4
GO:0048522 positive regulation of cellular process 4.108793e-4
GO:0002701 negative regulation of production of molecular mediator of immune response 4.245724e-4
GO:0033143 regulation of steroid hormone receptor signaling pathway 4.386240e-4
GO:2000602 regulation of interphase of mitotic cell cycle 4.521118e-4
GO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis 4.572177e-4
GO:0045191 regulation of isotype switching 4.592219e-4
GO:0010646 regulation of cell communication 4.602311e-4
GO:0060079 regulation of excitatory postsynaptic membrane potential 4.785733e-4
GO:0030098 lymphocyte differentiation 4.882657e-4
GO:0032232 negative regulation of actin filament bundle assembly 4.921232e-4
GO:0021953 central nervous system neuron differentiation 5.242472e-4
GO:0051347 positive regulation of transferase activity 5.314646e-4
GO:0007416 synapse assembly 5.317325e-4
GO:0000018 regulation of DNA recombination 5.322554e-4
GO:0045628 regulation of T-helper 2 cell differentiation 5.404706e-4
GO:0006436 tryptophanyl-tRNA aminoacylation 5.584445e-4
GO:0050796 regulation of insulin secretion 5.646514e-4
GO:0034261 negative regulation of Ras GTPase activity 5.740398e-4
GO:0035023 regulation of Rho protein signal transduction 5.812803e-4
GO:0032273 positive regulation of protein polymerization 5.980374e-4
GO:0051649 establishment of localization in cell 6.137664e-4
GO:0035910 ascending aorta morphogenesis 6.248866e-4
GO:2000761 positive regulation of N-terminal peptidyl-lysine acetylation 6.248866e-4
GO:0045921 positive regulation of exocytosis 6.252226e-4
GO:0016572 histone phosphorylation 6.253563e-4
GO:0007218 neuropeptide signaling pathway 6.364807e-4
GO:0090263 positive regulation of canonical Wnt receptor signaling pathway 6.410088e-4
GO:0032989 cellular component morphogenesis 6.489124e-4
GO:0015908 fatty acid transport 6.501494e-4
GO:0061304 retinal blood vessel morphogenesis 6.564344e-4
GO:0070574 cadmium ion transmembrane transport 6.564344e-4
GO:0042110 T cell activation 6.606928e-4
GO:0007204 elevation of cytosolic calcium ion concentration 6.693373e-4
GO:0031960 response to corticosteroid stimulus 7.361745e-4
GO:0060413 atrial septum morphogenesis 7.393415e-4
GO:0060872 semicircular canal development 7.397094e-4
GO:0007275 multicellular organismal development 7.399240e-4
GO:0090317 negative regulation of intracellular protein transport 7.467002e-4
GO:0048518 positive regulation of biological process 7.611245e-4
GO:0046475 glycerophospholipid catabolic process 7.672227e-4
GO:0046323 glucose import 7.672227e-4
GO:0032502 developmental process 7.821526e-4
GO:0007267 cell-cell signaling 8.026117e-4
GO:0045860 positive regulation of protein kinase activity 8.281662e-4
GO:0070727 cellular macromolecule localization 8.286913e-4
GO:0051318 G1 phase 8.380528e-4
GO:0006874 cellular calcium ion homeostasis 8.384885e-4
GO:0042701 progesterone secretion 8.411188e-4
GO:0032879 regulation of localization 8.423443e-4
GO:0048869 cellular developmental process 8.487077e-4
GO:0046928 regulation of neurotransmitter secretion 8.489197e-4
GO:0050869 negative regulation of B cell activation 8.494309e-4
GO:0051971 positive regulation of transmission of nerve impulse 8.790460e-4
GO:0032940 secretion by cell 8.859508e-4
GO:0051251 positive regulation of lymphocyte activation 8.875861e-4
GO:0010033 response to organic substance 8.935943e-4
GO:0060166 olfactory pit development 8.961999e-4
GO:0035444 nickel ion transmembrane transport 8.961999e-4
GO:0030154 cell differentiation 9.071063e-4
GO:0030317 sperm motility 9.088820e-4
GO:0097091 synaptic vesicle clustering 9.163473e-4
GO:0034613 cellular protein localization 9.301177e-4
GO:0030217 T cell differentiation 9.428088e-4
GO:0034137 positive regulation of toll-like receptor 2 signaling pathway 9.439882e-4
GO:0031161 phosphatidylinositol catabolic process 9.439882e-4
GO:0010983 positive regulation of high-density lipoprotein particle clearance 9.439882e-4
GO:0035304 regulation of protein dephosphorylation 9.445906e-4
GO:2000778 positive regulation of interleukin-6 secretion 9.505923e-4
GO:0043549 regulation of kinase activity 9.860164e-4
GO:0097113 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering 9.892058e-4
GO:0033692 cellular polysaccharide biosynthetic process 1.003720e-3
GO:0001659 temperature homeostasis 1.006692e-3
GO:0048871 multicellular organismal homeostasis 1.053236e-3
GO:0007223 Wnt receptor signaling pathway, calcium modulating pathway 1.056643e-3
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER 1.077217e-3
GO:0042592 homeostatic process 1.085074e-3
GO:0055080 cation homeostasis 1.097728e-3
GO:0048812 neuron projection morphogenesis 1.101159e-3
GO:0046823 negative regulation of nucleocytoplasmic transport 1.106721e-3
GO:0033554 cellular response to stress 1.154453e-3
GO:0071392 cellular response to estradiol stimulus 1.176193e-3
GO:0051567 histone H3-K9 methylation 1.184404e-3
GO:0001963 synaptic transmission, dopaminergic 1.184441e-3
GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity 1.191224e-3
GO:0050806 positive regulation of synaptic transmission 1.194373e-3
GO:2000758 positive regulation of peptidyl-lysine acetylation 1.194644e-3
GO:0009719 response to endogenous stimulus 1.198760e-3
GO:0048513 organ development 1.205834e-3
GO:0045666 positive regulation of neuron differentiation 1.218496e-3
GO:0032231 regulation of actin filament bundle assembly 1.222221e-3
GO:0042221 response to chemical stimulus 1.240385e-3
GO:0051965 positive regulation of synapse assembly 1.257281e-3
GO:0007417 central nervous system development 1.258708e-3
GO:0009582 detection of abiotic stimulus 1.266312e-3
GO:0046634 regulation of alpha-beta T cell activation 1.270507e-3
GO:0007341 penetration of zona pellucida 1.279838e-3
GO:2000117 negative regulation of cysteine-type endopeptidase activity 1.293620e-3
GO:0035108 limb morphogenesis 1.310581e-3
GO:0031016 pancreas development 1.328710e-3
GO:0045786 negative regulation of cell cycle 1.339555e-3
GO:0046165 alcohol biosynthetic process 1.341293e-3
GO:0042060 wound healing 1.343219e-3
GO:0010719 negative regulation of epithelial to mesenchymal transition 1.390717e-3
GO:0051492 regulation of stress fiber assembly 1.410573e-3
GO:0050871 positive regulation of B cell activation 1.422097e-3
GO:0033146 regulation of estrogen receptor signaling pathway 1.480768e-3
GO:0045956 positive regulation of calcium ion-dependent exocytosis 1.480768e-3
GO:0060840 artery development 1.485602e-3
GO:0097105 presynaptic membrane assembly 1.486274e-3
GO:0031646 positive regulation of neurological system process 1.495575e-3
GO:0042113 B cell activation 1.509087e-3
GO:0048752 semicircular canal morphogenesis 1.512847e-3
GO:0035786 protein complex oligomerization 1.577466e-3
GO:0003289 atrial septum primum morphogenesis 1.591946e-3
GO:0002710 negative regulation of T cell mediated immunity 1.599923e-3
GO:0009725 response to hormone stimulus 1.615764e-3
GO:0003283 atrial septum development 1.625363e-3
GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism 1.636858e-3
GO:0006694 steroid biosynthetic process 1.641615e-3
GO:0051338 regulation of transferase activity 1.651117e-3
GO:0048844 artery morphogenesis 1.665223e-3
GO:0010771 negative regulation of cell morphogenesis involved in differentiation 1.709791e-3
GO:0060284 regulation of cell development 1.763671e-3
GO:0070460 thyroid-stimulating hormone secretion 1.807876e-3
GO:0030888 regulation of B cell proliferation 1.821654e-3
GO:0000080 G1 phase of mitotic cell cycle 1.834592e-3
GO:0044242 cellular lipid catabolic process 1.865091e-3
GO:0048666 neuron development 1.885487e-3
GO:0060173 limb development 1.891905e-3
GO:0071322 cellular response to carbohydrate stimulus 1.899335e-3
GO:0032271 regulation of protein polymerization 1.900323e-3
GO:0097120 receptor localization to synapse 1.924724e-3
GO:0072578 neurotransmitter-gated ion channel clustering 1.924724e-3
GO:0006700 C21-steroid hormone biosynthetic process 1.924724e-3
GO:0046907 intracellular transport 1.960349e-3
GO:0007093 mitotic cell cycle checkpoint 1.963592e-3
GO:0070495 negative regulation of thrombin receptor signaling pathway 1.978717e-3
GO:0051622 negative regulation of norepinephrine uptake 1.978717e-3
GO:0051585 negative regulation of dopamine uptake 1.978717e-3
GO:0050812 regulation of acyl-CoA biosynthetic process 1.978717e-3
GO:0072503 cellular divalent inorganic cation homeostasis 2.005311e-3
GO:0021515 cell differentiation in spinal cord 2.019190e-3
GO:0042127 regulation of cell proliferation 2.021026e-3
GO:0033273 response to vitamin 2.021708e-3
GO:0060766 negative regulation of androgen receptor signaling pathway 2.106253e-3
GO:0060586 multicellular organismal iron ion homeostasis 2.114643e-3
GO:0015684 ferrous iron transport 2.114643e-3
GO:0022603 regulation of anatomical structure morphogenesis 2.134379e-3
GO:0009653 anatomical structure morphogenesis 2.135861e-3
GO:0044089 positive regulation of cellular component biogenesis 2.148288e-3
GO:0010986 positive regulation of lipoprotein particle clearance 2.162436e-3
GO:0071158 positive regulation of cell cycle arrest 2.177614e-3
GO:0097090 presynaptic membrane organization 2.180433e-3
GO:0051224 negative regulation of protein transport 2.200231e-3
GO:0048791 calcium ion-dependent exocytosis of neurotransmitter 2.228809e-3
GO:0045578 negative regulation of B cell differentiation 2.253175e-3
GO:0007601 visual perception 2.267475e-3
GO:0060078 regulation of postsynaptic membrane potential 2.317900e-3
GO:0050670 regulation of lymphocyte proliferation 2.417370e-3
GO:0051712 positive regulation of killing of cells of other organism 2.457662e-3
GO:0032387 negative regulation of intracellular transport 2.464121e-3
GO:0010812 negative regulation of cell-substrate adhesion 2.480563e-3
GO:0032535 regulation of cellular component size 2.506309e-3
GO:0051641 cellular localization 2.513508e-3
GO:0009583 detection of light stimulus 2.522969e-3
GO:0048148 behavioral response to cocaine 2.532572e-3
GO:0034637 cellular carbohydrate biosynthetic process 2.548141e-3
GO:0001944 vasculature development 2.629939e-3
GO:0030177 positive regulation of Wnt receptor signaling pathway 2.638003e-3
GO:0051057 positive regulation of small GTPase mediated signal transduction 2.641467e-3
GO:0032410 negative regulation of transporter activity 2.672501e-3
GO:0050953 sensory perception of light stimulus 2.679265e-3
GO:0045582 positive regulation of T cell differentiation 2.698106e-3
GO:0045453 bone resorption 2.721760e-3
GO:0032944 regulation of mononuclear cell proliferation 2.727370e-3
GO:0008653 lipopolysaccharide metabolic process 2.737269e-3
GO:0035307 positive regulation of protein dephosphorylation 2.746511e-3
GO:0021517 ventral spinal cord development 2.779276e-3
GO:0007254 JNK cascade 2.828933e-3
GO:0051026 chiasma assembly 2.837180e-3
GO:0035425 autocrine signaling 2.839324e-3
GO:0035426 extracellular matrix-cell signaling 2.839324e-3
GO:0045597 positive regulation of cell differentiation 2.848900e-3
GO:0002643 regulation of tolerance induction 2.861320e-3
GO:0008090 retrograde axon cargo transport 2.864921e-3
GO:0051497 negative regulation of stress fiber assembly 2.864921e-3
GO:0002696 positive regulation of leukocyte activation 2.894696e-3
GO:0002820 negative regulation of adaptive immune response 2.916751e-3
GO:0030178 negative regulation of Wnt receptor signaling pathway 2.926642e-3
GO:0035306 positive regulation of dephosphorylation 2.928656e-3
GO:0009612 response to mechanical stimulus 2.952903e-3
GO:0000086 G2/M transition of mitotic cell cycle 3.003420e-3
GO:0002521 leukocyte differentiation 3.004662e-3
GO:0097029 mature dendritic cell differentiation 3.018235e-3
GO:0046960 sensitization 3.018235e-3
GO:0043309 regulation of eosinophil degranulation 3.018235e-3
GO:0007049 cell cycle 3.029450e-3
GO:0046879 hormone secretion 3.065481e-3
GO:0017158 regulation of calcium ion-dependent exocytosis 3.083162e-3
GO:0090200 positive regulation of release of cytochrome c from mitochondria 3.120305e-3
GO:0007155 cell adhesion 3.133130e-3
GO:0002328 pro-B cell differentiation 3.197828e-3
GO:0032024 positive regulation of insulin secretion 3.203525e-3
GO:0070663 regulation of leukocyte proliferation 3.236496e-3
GO:0033147 negative regulation of estrogen receptor signaling pathway 3.262024e-3
GO:0060411 cardiac septum morphogenesis 3.278839e-3
GO:0009581 detection of external stimulus 3.311478e-3
GO:0007269 neurotransmitter secretion 3.324895e-3
GO:0071842 cellular component organization at cellular level 3.383080e-3
GO:0071379 cellular response to prostaglandin stimulus 3.426314e-3
GO:0006875 cellular metal ion homeostasis 3.442370e-3
GO:0030833 regulation of actin filament polymerization 3.452890e-3
GO:0031399 regulation of protein modification process 3.505604e-3
GO:0060547 negative regulation of necrotic cell death 3.527534e-3
GO:0016571 histone methylation 3.554783e-3
GO:0051384 response to glucocorticoid stimulus 3.593825e-3
GO:0016051 carbohydrate biosynthetic process 3.616377e-3
GO:0050801 ion homeostasis 3.690532e-3
GO:0044338 canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation 3.728159e-3
GO:0044339 canonical Wnt receptor signaling pathway involved in osteoblast differentiation 3.728159e-3
GO:0042446 hormone biosynthetic process 3.738253e-3
GO:0051480 cytosolic calcium ion homeostasis 3.739693e-3
GO:0007154 cell communication 3.786500e-3
GO:0019220 regulation of phosphate metabolic process 3.786966e-3
GO:0022610 biological adhesion 3.804181e-3
GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 3.820925e-3
GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation 3.887638e-3
GO:0010810 regulation of cell-substrate adhesion 3.893413e-3
GO:0035137 hindlimb morphogenesis 3.905152e-3
GO:0048169 regulation of long-term neuronal synaptic plasticity 3.905306e-3
GO:0034260 negative regulation of GTPase activity 3.926609e-3
GO:0051589 negative regulation of neurotransmitter transport 3.926609e-3
GO:0023052 signaling 3.936840e-3
GO:0006629 lipid metabolic process 3.941929e-3
GO:0050804 regulation of synaptic transmission 3.958286e-3
GO:0044065 regulation of respiratory system process 3.984549e-3
GO:0016080 synaptic vesicle targeting 3.988925e-3
GO:0051249 regulation of lymphocyte activation 4.016403e-3
GO:0051593 response to folic acid 4.038121e-3
GO:0015866 ADP transport 4.054901e-3
GO:0035623 renal glucose absorption 4.054901e-3
GO:0006869 lipid transport 4.107889e-3
GO:0043901 negative regulation of multi-organism process 4.194624e-3
GO:0009743 response to carbohydrate stimulus 4.224416e-3
GO:0060687 regulation of branching involved in prostate gland morphogenesis 4.233381e-3
GO:0033157 regulation of intracellular protein transport 4.261995e-3
GO:0097022 lymphocyte migration into lymph node 4.286647e-3
GO:0072610 interleukin-12 secretion 4.286647e-3
GO:0001692 histamine metabolic process 4.286647e-3
GO:0006851 mitochondrial calcium ion transport 4.286647e-3
GO:0043648 dicarboxylic acid metabolic process 4.329889e-3
GO:0007042 lysosomal lumen acidification 4.335379e-3
GO:0002649 regulation of tolerance induction to self antigen 4.335379e-3
GO:2000026 regulation of multicellular organismal development 4.425441e-3
GO:0051051 negative regulation of transport 4.433931e-3
GO:0035556 intracellular signal transduction 4.523495e-3
GO:0097104 postsynaptic membrane assembly 4.591170e-3
GO:0097119 postsynaptic density protein 95 clustering 4.591170e-3
GO:0002244 hemopoietic progenitor cell differentiation 4.599816e-3
GO:0002087 regulation of respiratory gaseous exchange by neurological system process 4.602561e-3
GO:0045859 regulation of protein kinase activity 4.620966e-3
GO:0060159 regulation of dopamine receptor signaling pathway 4.650915e-3
GO:0050777 negative regulation of immune response 4.688819e-3
GO:0007628 adult walking behavior 4.735409e-3
GO:0051048 negative regulation of secretion 4.750567e-3
GO:0001915 negative regulation of T cell mediated cytotoxicity 4.757638e-3
GO:0097070 ductus arteriosus closure 4.786880e-3
GO:0070314 G1 to G0 transition 4.800256e-3
GO:0051612 negative regulation of serotonin uptake 4.800256e-3
GO:0016050 vesicle organization 4.811596e-3
GO:0002698 negative regulation of immune effector process 4.833449e-3
GO:0002467 germinal center formation 4.840997e-3
GO:0060412 ventricular septum morphogenesis 4.889400e-3
GO:0051588 regulation of neurotransmitter transport 4.905225e-3
GO:0021987 cerebral cortex development 4.924147e-3
GO:0050867 positive regulation of cell activation 4.984384e-3
GO:0034383 low-density lipoprotein particle clearance 5.018843e-3
GO:0050767 regulation of neurogenesis 5.036181e-3
GO:2000514 regulation of CD4-positive, alpha-beta T cell activation 5.036766e-3
GO:0071295 cellular response to vitamin 5.041101e-3
GO:0035019 somatic stem cell maintenance 5.045193e-3
GO:0097026 dendritic cell dendrite assembly 5.063301e-3
GO:0006438 valyl-tRNA aminoacylation 5.063301e-3
GO:0032413 negative regulation of ion transmembrane transporter activity 5.078940e-3
GO:0031017 exocrine pancreas development 5.109680e-3
GO:0031400 negative regulation of protein modification process 5.114000e-3
GO:0001952 regulation of cell-matrix adhesion 5.240143e-3
GO:0070848 response to growth factor stimulus 5.266194e-3
GO:0071481 cellular response to X-ray 5.271983e-3
GO:0032602 chemokine production 5.282753e-3
GO:0006048 UDP-N-acetylglucosamine biosynthetic process 5.282753e-3
GO:0016043 cellular component organization 5.283249e-3
GO:0051329 interphase of mitotic cell cycle 5.445124e-3
GO:0016339 calcium-dependent cell-cell adhesion 5.452610e-3
GO:0008202 steroid metabolic process 5.476804e-3
GO:0018272 protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine 5.511085e-3
GO:0022615 protein to membrane docking 5.511085e-3
GO:0014009 glial cell proliferation 5.523034e-3
GO:0001649 osteoblast differentiation 5.537746e-3
GO:0033993 response to lipid 5.594475e-3
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 5.653884e-3
GO:0031175 neuron projection development 5.700928e-3
GO:0051047 positive regulation of secretion 5.704059e-3
GO:0065009 regulation of molecular function 5.727850e-3