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Novel motif:130

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name:motif130_TTTCAAACNCCC

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0042074 cell migration involved in gastrulation 3.459862e-13
GO:0006020 inositol metabolic process 1.026231e-12
GO:0034377 plasma lipoprotein particle assembly 3.705502e-11
GO:0008078 mesodermal cell migration 3.991508e-11
GO:0034379 very-low-density lipoprotein particle assembly 3.994037e-10
GO:0010269 response to selenium ion 1.253411e-9
GO:0000185 activation of MAPKKK activity 1.403009e-9
GO:0007509 mesoderm migration involved in gastrulation 8.210488e-9
GO:0051901 positive regulation of mitochondrial depolarization 1.561253e-8
GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 2.936635e-8
GO:0002889 regulation of immunoglobulin mediated immune response 3.948306e-8
GO:0032964 collagen biosynthetic process 4.961207e-8
GO:0001957 intramembranous ossification 7.044383e-8
GO:0002712 regulation of B cell mediated immunity 7.541009e-8
GO:0031536 positive regulation of exit from mitosis 7.637238e-8
GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 1.541378e-7
GO:0046543 development of secondary female sexual characteristics 1.774175e-7
GO:0019751 polyol metabolic process 1.985985e-7
GO:0000075 cell cycle checkpoint 2.125569e-7
GO:0006689 ganglioside catabolic process 3.270192e-7
GO:0003307 regulation of Wnt receptor signaling pathway involved in heart development 4.478891e-7
GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway 6.450902e-7
GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 6.598272e-7
GO:0010954 positive regulation of protein processing 6.898868e-7
GO:0035814 negative regulation of renal sodium excretion 6.952313e-7
GO:0071156 regulation of cell cycle arrest 6.993046e-7
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation 7.621984e-7
GO:0045136 development of secondary sexual characteristics 9.100880e-7
GO:0071316 cellular response to nicotine 1.095117e-6
GO:0048853 forebrain morphogenesis 1.260072e-6
GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation 1.303206e-6
GO:0070245 positive regulation of thymocyte apoptosis 1.430519e-6
GO:0070230 positive regulation of lymphocyte apoptosis 1.442893e-6
GO:0070417 cellular response to cold 1.740725e-6
GO:0070243 regulation of thymocyte apoptosis 1.981187e-6
GO:0060167 regulation of adenosine receptor signaling pathway 2.124738e-6
GO:0033555 multicellular organismal response to stress 2.288917e-6
GO:0042542 response to hydrogen peroxide 3.021802e-6
GO:0030514 negative regulation of BMP signaling pathway 3.403390e-6
GO:0070234 positive regulation of T cell apoptosis 3.573805e-6
GO:0022027 interkinetic nuclear migration 3.762978e-6
GO:0055093 response to hyperoxia 5.092982e-6
GO:0031133 regulation of axon diameter 5.432785e-6
GO:0007093 mitotic cell cycle checkpoint 6.711649e-6
GO:0043585 nose morphogenesis 7.117160e-6
GO:0033590 response to cobalamin 7.449616e-6
GO:0006117 acetaldehyde metabolic process 7.449616e-6
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 7.504429e-6
GO:0043320 natural killer cell degranulation 7.697330e-6
GO:0003308 negative regulation of Wnt receptor signaling pathway involved in heart development 8.161387e-6
GO:0007051 spindle organization 8.183523e-6
GO:0070232 regulation of T cell apoptosis 8.421221e-6
GO:0060343 trabecula formation 8.658899e-6
GO:0006097 glyoxylate cycle 8.982419e-6
GO:0051293 establishment of spindle localization 9.051827e-6
GO:0035419 activation of MAPK activity involved in innate immune response 9.138965e-6
GO:0034389 lipid particle organization 9.160432e-6
GO:0046491 L-methylmalonyl-CoA metabolic process 9.755547e-6
GO:0016554 cytidine to uridine editing 9.755547e-6
GO:0045191 regulation of isotype switching 1.018181e-5
GO:0035556 intracellular signal transduction 1.164228e-5
GO:0042159 lipoprotein catabolic process 1.176892e-5
GO:0000077 DNA damage checkpoint 1.182433e-5
GO:0002739 regulation of cytokine secretion involved in immune response 1.208909e-5
GO:0031627 telomeric loop formation 1.281151e-5
GO:0035121 tail morphogenesis 1.383272e-5
GO:0050768 negative regulation of neurogenesis 1.540835e-5
GO:0042360 vitamin E metabolic process 1.574042e-5
GO:0030844 positive regulation of intermediate filament depolymerization 1.574042e-5
GO:0042596 fear response 1.583964e-5
GO:0032926 negative regulation of activin receptor signaling pathway 1.586138e-5
GO:0061383 trabecula morphogenesis 1.592792e-5
GO:0030510 regulation of BMP signaling pathway 1.598767e-5
GO:0009264 deoxyribonucleotide catabolic process 1.600725e-5
GO:0030953 astral microtubule organization 1.655955e-5
GO:0009155 purine deoxyribonucleotide catabolic process 1.692276e-5
GO:0002740 negative regulation of cytokine secretion involved in immune response 1.740071e-5
GO:0090081 regulation of heart induction by regulation of canonical Wnt receptor signaling pathway 1.753528e-5
GO:0019882 antigen processing and presentation 1.870326e-5
GO:0046853 inositol or phosphatidylinositol phosphorylation 1.927763e-5
GO:0060389 pathway-restricted SMAD protein phosphorylation 1.983906e-5
GO:0060346 bone trabecula formation 2.124672e-5
GO:0007626 locomotory behavior 2.351911e-5
GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation 2.352729e-5
GO:0006779 porphyrin-containing compound biosynthetic process 3.172620e-5
GO:0000302 response to reactive oxygen species 3.208790e-5
GO:0045065 cytotoxic T cell differentiation 3.490473e-5
GO:0071206 establishment of protein localization to juxtaparanode region of axon 3.552397e-5
GO:0060168 positive regulation of adenosine receptor signaling pathway 3.552397e-5
GO:0030149 sphingolipid catabolic process 3.562944e-5
GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 3.577875e-5
GO:0021509 roof plate formation 4.045209e-5
GO:0032536 regulation of cell projection size 4.079373e-5
GO:0071300 cellular response to retinoic acid 4.115629e-5
GO:0007605 sensory perception of sound 4.260634e-5
GO:0060744 mammary gland branching involved in thelarche 4.438851e-5
GO:0045416 positive regulation of interleukin-8 biosynthetic process 4.644057e-5
GO:0006285 base-excision repair, AP site formation 4.727291e-5
GO:0046479 glycosphingolipid catabolic process 4.764168e-5
GO:0042267 natural killer cell mediated cytotoxicity 5.080972e-5
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 5.336818e-5
GO:0000722 telomere maintenance via recombination 5.447727e-5
GO:0006312 mitotic recombination 5.510234e-5
GO:0031860 telomeric 3' overhang formation 5.536820e-5
GO:0048592 eye morphogenesis 5.558396e-5
GO:0032924 activin receptor signaling pathway 5.619330e-5
GO:0046501 protoporphyrinogen IX metabolic process 5.661484e-5
GO:0045682 regulation of epidermis development 5.768570e-5
GO:0045007 depurination 5.769286e-5
GO:0010994 free ubiquitin chain polymerization 5.769286e-5
GO:0071312 cellular response to alkaloid 5.875769e-5
GO:0034505 tooth mineralization 5.938971e-5
GO:0006499 N-terminal protein myristoylation 5.981674e-5
GO:0031570 DNA integrity checkpoint 6.110909e-5
GO:0031064 negative regulation of histone deacetylation 6.119571e-5
GO:0044319 wound healing, spreading of cells 6.122791e-5
GO:0045994 positive regulation of translational initiation by iron 6.318061e-5
GO:0002037 negative regulation of L-glutamate transport 6.318061e-5
GO:0042137 sequestering of neurotransmitter 6.493966e-5
GO:0035023 regulation of Rho protein signal transduction 6.770801e-5
GO:0040001 establishment of mitotic spindle localization 6.782551e-5
GO:0003254 regulation of membrane depolarization 7.137611e-5
GO:0038007 netrin-activated signaling pathway 7.147945e-5
GO:0007266 Rho protein signal transduction 7.181259e-5
GO:0051260 protein homooligomerization 7.249038e-5
GO:0002863 positive regulation of inflammatory response to antigenic stimulus 7.624930e-5
GO:0090130 tissue migration 8.271145e-5
GO:0046931 pore complex assembly 8.377495e-5
GO:0009062 fatty acid catabolic process 8.536066e-5
GO:0007265 Ras protein signal transduction 8.767794e-5
GO:0051532 regulation of NFAT protein import into nucleus 8.813409e-5
GO:0051896 regulation of protein kinase B signaling cascade 8.937593e-5
GO:0019230 proprioception 9.189377e-5
GO:0009151 purine deoxyribonucleotide metabolic process 9.881740e-5
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 1.001730e-4
GO:0060621 negative regulation of cholesterol import 1.004798e-4
GO:0034384 high-density lipoprotein particle clearance 1.013728e-4
GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 1.018117e-4
GO:0060157 urinary bladder development 1.027866e-4
GO:0002637 regulation of immunoglobulin production 1.034489e-4
GO:0006635 fatty acid beta-oxidation 1.065727e-4
GO:0002088 lens development in camera-type eye 1.078274e-4
GO:0000132 establishment of mitotic spindle orientation 1.081911e-4
GO:0001909 leukocyte mediated cytotoxicity 1.112993e-4
GO:0060689 cell differentiation involved in salivary gland development 1.123442e-4
GO:0001306 age-dependent response to oxidative stress 1.129610e-4
GO:0033025 regulation of mast cell apoptosis 1.168987e-4
GO:0022616 DNA strand elongation 1.182541e-4
GO:0051798 positive regulation of hair follicle development 1.221972e-4
GO:0000060 protein import into nucleus, translocation 1.279044e-4
GO:0032319 regulation of Rho GTPase activity 1.285876e-4
GO:0000086 G2/M transition of mitotic cell cycle 1.305840e-4
GO:0032862 activation of Rho GTPase activity 1.327488e-4
GO:0051298 centrosome duplication 1.328807e-4
GO:0043243 positive regulation of protein complex disassembly 1.348523e-4
GO:0006447 regulation of translational initiation by iron 1.427113e-4
GO:0009967 positive regulation of signal transduction 1.446405e-4
GO:0050957 equilibrioception 1.531116e-4
GO:0032148 activation of protein kinase B activity 1.549023e-4
GO:2000309 positive regulation of tumor necrosis factor (ligand) superfamily member 11 production 1.605790e-4
GO:0046466 membrane lipid catabolic process 1.649809e-4
GO:0021877 forebrain neuron fate commitment 1.660178e-4
GO:0002861 regulation of inflammatory response to antigenic stimulus 1.672197e-4
GO:0051488 activation of anaphase-promoting complex activity 1.674325e-4
GO:0034380 high-density lipoprotein particle assembly 1.702773e-4
GO:0019048 virus-host interaction 1.703893e-4
GO:0021893 cerebral cortex GABAergic interneuron fate commitment 1.744055e-4
GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment 1.744055e-4
GO:0016973 poly(A)+ mRNA export from nucleus 1.748874e-4
GO:0051602 response to electrical stimulus 1.774143e-4
GO:0071299 cellular response to vitamin A 1.777338e-4
GO:0042772 DNA damage response, signal transduction resulting in transcription 1.817695e-4
GO:0042994 cytoplasmic sequestering of transcription factor 1.920639e-4
GO:0070159 mitochondrial threonyl-tRNA aminoacylation 1.968711e-4
GO:0001845 phagolysosome assembly 1.984887e-4
GO:0010721 negative regulation of cell development 1.998285e-4
GO:0003198 epithelial to mesenchymal transition involved in endocardial cushion formation 2.040187e-4
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 2.104603e-4
GO:0010564 regulation of cell cycle process 2.156503e-4
GO:0060686 negative regulation of prostatic bud formation 2.221145e-4
GO:0048048 embryonic eye morphogenesis 2.290954e-4
GO:0060973 cell migration involved in heart development 2.300566e-4
GO:0007221 positive regulation of transcription of Notch receptor target 2.315967e-4
GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase 2.320357e-4
GO:0003032 detection of oxygen 2.352051e-4
GO:2000836 positive regulation of androgen secretion 2.426754e-4
GO:0006768 biotin metabolic process 2.426754e-4
GO:2000500 positive regulation of induction of apoptosis in response to chemical stimulus 2.426754e-4
GO:0032526 response to retinoic acid 2.450908e-4
GO:0005980 glycogen catabolic process 2.471656e-4
GO:0010189 vitamin E biosynthetic process 2.474249e-4
GO:0033013 tetrapyrrole metabolic process 2.494567e-4
GO:0071779 G1/S transition checkpoint 2.505278e-4
GO:2000678 negative regulation of transcription regulatory region DNA binding 2.515372e-4
GO:0001662 behavioral fear response 2.549454e-4
GO:0019101 female somatic sex determination 2.615980e-4
GO:0042703 menstruation 2.615980e-4
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 2.636480e-4
GO:0097151 positive regulation of inhibitory postsynaptic membrane potential 2.677162e-4
GO:0048320 axial mesoderm formation 2.735408e-4
GO:0060620 regulation of cholesterol import 2.735408e-4
GO:0015824 proline transport 2.754645e-4
GO:0002431 Fc receptor mediated stimulatory signaling pathway 2.754672e-4
GO:0001805 positive regulation of type III hypersensitivity 2.754672e-4
GO:0031848 protection from non-homologous end joining at telomere 2.765684e-4
GO:0072331 signal transduction by p53 class mediator 2.779944e-4
GO:0006471 protein ADP-ribosylation 2.789399e-4
GO:0060816 random inactivation of X chromosome 2.836229e-4
GO:0030330 DNA damage response, signal transduction by p53 class mediator 2.860590e-4
GO:0009258 10-formyltetrahydrofolate catabolic process 2.866199e-4
GO:0051181 cofactor transport 2.888697e-4
GO:0006333 chromatin assembly or disassembly 3.037253e-4
GO:0010874 regulation of cholesterol efflux 3.113046e-4
GO:0007468 regulation of rhodopsin gene expression 3.153197e-4
GO:0072355 histone H3-T3 phosphorylation 3.227257e-4
GO:0008049 male courtship behavior 3.227257e-4
GO:0001963 synaptic transmission, dopaminergic 3.351715e-4
GO:0072329 monocarboxylic acid catabolic process 3.415854e-4
GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway 3.536286e-4
GO:0051955 regulation of amino acid transport 3.610339e-4
GO:0010799 regulation of peptidyl-threonine phosphorylation 3.611372e-4
GO:0045112 integrin biosynthetic process 3.624968e-4
GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint 3.629248e-4
GO:0043589 skin morphogenesis 3.695598e-4
GO:0035966 response to topologically incorrect protein 3.703281e-4
GO:0090082 positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway 3.723830e-4
GO:0006435 threonyl-tRNA aminoacylation 3.723830e-4
GO:0048593 camera-type eye morphogenesis 3.723899e-4
GO:0090381 regulation of heart induction 3.759215e-4
GO:0030825 positive regulation of cGMP metabolic process 3.790349e-4
GO:0045629 negative regulation of T-helper 2 cell differentiation 3.879881e-4
GO:0000212 meiotic spindle organization 3.942859e-4
GO:0032730 positive regulation of interleukin-1 alpha production 3.948805e-4
GO:0071827 plasma lipoprotein particle organization 3.983651e-4
GO:0002089 lens morphogenesis in camera-type eye 3.990391e-4
GO:0051964 negative regulation of synapse assembly 4.242158e-4
GO:0002432 granuloma formation 4.276643e-4
GO:0002209 behavioral defense response 4.293439e-4
GO:0045684 positive regulation of epidermis development 4.306241e-4
GO:2000045 regulation of G1/S transition of mitotic cell cycle 4.515855e-4
GO:0006778 porphyrin-containing compound metabolic process 4.517657e-4
GO:0032321 positive regulation of Rho GTPase activity 4.520780e-4
GO:0006102 isocitrate metabolic process 4.575560e-4
GO:0048265 response to pain 4.584246e-4
GO:0072676 lymphocyte migration 4.614401e-4
GO:0072500 negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor 4.639331e-4
GO:0032963 collagen metabolic process 4.721922e-4
GO:0010826 negative regulation of centrosome duplication 4.889648e-4
GO:0007091 mitotic metaphase/anaphase transition 4.905295e-4
GO:0007243 intracellular protein kinase cascade 5.006351e-4
GO:0051900 regulation of mitochondrial depolarization 5.124336e-4
GO:0019395 fatty acid oxidation 5.141351e-4
GO:0060056 mammary gland involution 5.294053e-4
GO:0051701 interaction with host 5.442138e-4
GO:0006642 triglyceride mobilization 5.459695e-4
GO:0035313 wound healing, spreading of epidermal cells 5.482796e-4
GO:0010875 positive regulation of cholesterol efflux 5.561787e-4
GO:0031575 mitotic cell cycle G1/S transition checkpoint 5.574765e-4
GO:0000272 polysaccharide catabolic process 5.634521e-4
GO:0030859 polarized epithelial cell differentiation 5.742219e-4
GO:0050954 sensory perception of mechanical stimulus 5.797638e-4
GO:0044242 cellular lipid catabolic process 5.798955e-4
GO:0042992 negative regulation of transcription factor import into nucleus 5.905464e-4
GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway 5.982928e-4
GO:0051259 protein oligomerization 6.275441e-4
GO:0010800 positive regulation of peptidyl-threonine phosphorylation 6.361815e-4
GO:0060762 regulation of branching involved in mammary gland duct morphogenesis 6.373013e-4
GO:0014028 notochord formation 6.431738e-4
GO:0006297 nucleotide-excision repair, DNA gap filling 6.516216e-4
GO:0007164 establishment of tissue polarity 6.728535e-4
GO:0071346 cellular response to interferon-gamma 6.898057e-4
GO:0050717 positive regulation of interleukin-1 alpha secretion 7.002067e-4
GO:0035470 positive regulation of vascular wound healing 7.002067e-4
GO:0007223 Wnt receptor signaling pathway, calcium modulating pathway 7.012723e-4
GO:0000956 nuclear-transcribed mRNA catabolic process 7.164947e-4
GO:0051461 positive regulation of corticotropin secretion 7.171646e-4
GO:0061014 positive regulation of mRNA catabolic process 7.200266e-4
GO:0044247 cellular polysaccharide catabolic process 7.218923e-4
GO:0009251 glucan catabolic process 7.218923e-4
GO:0006783 heme biosynthetic process 7.247659e-4
GO:0002456 T cell mediated immunity 7.330050e-4
GO:0009109 coenzyme catabolic process 7.496320e-4
GO:0006749 glutathione metabolic process 7.530821e-4
GO:0000084 S phase of mitotic cell cycle 7.778495e-4
GO:0048239 negative regulation of DNA recombination at telomere 7.795550e-4
GO:0051320 S phase 7.834211e-4
GO:0050767 regulation of neurogenesis 7.867060e-4
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 7.961347e-4
GO:0001738 morphogenesis of a polarized epithelium 8.026380e-4
GO:0009394 2'-deoxyribonucleotide metabolic process 8.056879e-4
GO:0045471 response to ethanol 8.164649e-4
GO:0051961 negative regulation of nervous system development 8.316050e-4
GO:0010742 macrophage derived foam cell differentiation 8.331190e-4
GO:0048773 erythrophore differentiation 8.331190e-4
GO:0034021 response to silicon dioxide 8.331190e-4
GO:0003069 vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure 8.331190e-4
GO:0001315 age-dependent response to reactive oxygen species 8.331190e-4
GO:0045084 positive regulation of interleukin-12 biosynthetic process 8.392905e-4
GO:0046148 pigment biosynthetic process 8.504187e-4
GO:0006986 response to unfolded protein 8.526403e-4
GO:0072668 tubulin complex biogenesis 8.697396e-4
GO:0060088 auditory receptor cell stereocilium organization 8.793131e-4
GO:0007253 cytoplasmic sequestering of NF-kappaB 8.876815e-4
GO:0003181 atrioventricular valve morphogenesis 8.947012e-4
GO:0014054 positive regulation of gamma-aminobutyric acid secretion 9.053008e-4
GO:0007096 regulation of exit from mitosis 9.066253e-4
GO:0033189 response to vitamin A 9.087525e-4
GO:0002693 positive regulation of cellular extravasation 9.110114e-4
GO:0001707 mesoderm formation 9.306421e-4
GO:0070228 regulation of lymphocyte apoptosis 9.395434e-4
GO:0002407 dendritic cell chemotaxis 9.598353e-4
GO:0061013 regulation of mRNA catabolic process 9.851503e-4
GO:0002072 optic cup morphogenesis involved in camera-type eye development 1.023420e-3
GO:0018993 somatic sex determination 1.031681e-3
GO:0010890 positive regulation of sequestering of triglyceride 1.031681e-3
GO:0061017 hepatoblast differentiation 1.048697e-3
GO:0045199 maintenance of epithelial cell apical/basal polarity 1.048697e-3
GO:0045830 positive regulation of isotype switching 1.054908e-3
GO:2000242 negative regulation of reproductive process 1.068774e-3
GO:0034763 negative regulation of transmembrane transport 1.083022e-3
GO:0003309 type B pancreatic cell differentiation 1.102184e-3
GO:0002883 regulation of hypersensitivity 1.115067e-3
GO:0009057 macromolecule catabolic process 1.115623e-3
GO:0051897 positive regulation of protein kinase B signaling cascade 1.132620e-3
GO:0006271 DNA strand elongation involved in DNA replication 1.135527e-3
GO:0048854 brain morphogenesis 1.140018e-3
GO:0061048 negative regulation of branching involved in lung morphogenesis 1.148372e-3
GO:0060695 negative regulation of cholesterol transporter activity 1.148372e-3
GO:0001812 positive regulation of type I hypersensitivity 1.148372e-3
GO:0042308 negative regulation of protein import into nucleus 1.173611e-3
GO:0044403 symbiosis, encompassing mutualism through parasitism 1.181689e-3
GO:0002074 extraocular skeletal muscle development 1.192138e-3
GO:0033344 cholesterol efflux 1.203081e-3
GO:0050884 neuromuscular process controlling posture 1.203629e-3
GO:0048266 behavioral response to pain 1.203629e-3
GO:0032796 uropod organization 1.203903e-3
GO:0048298 positive regulation of isotype switching to IgA isotypes 1.226007e-3
GO:0035356 cellular triglyceride homeostasis 1.233947e-3
GO:0043132 NAD transport 1.233947e-3
GO:0030421 defecation 1.233947e-3
GO:0001736 establishment of planar polarity 1.247938e-3
GO:0051607 defense response to virus 1.248004e-3
GO:0016571 histone methylation 1.253054e-3
GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity 1.257534e-3
GO:0033032 regulation of myeloid cell apoptosis 1.270360e-3
GO:0032495 response to muramyl dipeptide 1.294728e-3
GO:0043316 cytotoxic T cell degranulation 1.299386e-3
GO:0048332 mesoderm morphogenesis 1.394434e-3
GO:0010812 negative regulation of cell-substrate adhesion 1.396901e-3
GO:0031115 negative regulation of microtubule polymerization 1.403818e-3
GO:0045872 positive regulation of rhodopsin gene expression 1.424896e-3
GO:0010883 regulation of lipid storage 1.431940e-3
GO:0007406 negative regulation of neuroblast proliferation 1.442348e-3
GO:0032633 interleukin-4 production 1.452822e-3
GO:0001865 NK T cell differentiation 1.452822e-3
GO:0045414 regulation of interleukin-8 biosynthetic process 1.453010e-3
GO:0071824 protein-DNA complex subunit organization 1.489058e-3
GO:0046784 intronless viral mRNA export from host nucleus 1.496627e-3
GO:0033628 regulation of cell adhesion mediated by integrin 1.498379e-3
GO:0048011 nerve growth factor receptor signaling pathway 1.499926e-3
GO:0006527 arginine catabolic process 1.503143e-3
GO:0007264 small GTPase mediated signal transduction 1.525739e-3
GO:0071549 cellular response to dexamethasone stimulus 1.531643e-3
GO:0051005 negative regulation of lipoprotein lipase activity 1.563741e-3
GO:0033089 positive regulation of T cell differentiation in thymus 1.626486e-3
GO:0002885 positive regulation of hypersensitivity 1.626486e-3
GO:0002891 positive regulation of immunoglobulin mediated immune response 1.655979e-3
GO:0032008 positive regulation of TOR signaling cascade 1.667256e-3
GO:0005977 glycogen metabolic process 1.685284e-3
GO:0051220 cytoplasmic sequestering of protein 1.685578e-3
GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis 1.685676e-3
GO:0034614 cellular response to reactive oxygen species 1.686736e-3
GO:0050435 beta-amyloid metabolic process 1.690075e-3
GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development 1.693151e-3
GO:0003061 positive regulation of the force of heart contraction by norepinephrine 1.693151e-3
GO:2000833 positive regulation of steroid hormone secretion 1.694158e-3
GO:0060117 auditory receptor cell development 1.709787e-3
GO:0045299 otolith mineralization 1.711873e-3
GO:0032790 ribosome disassembly 1.711873e-3
GO:0048147 negative regulation of fibroblast proliferation 1.736481e-3
GO:0022415 viral reproductive process 1.739717e-3
GO:0060601 lateral sprouting from an epithelium 1.741729e-3
GO:0060326 cell chemotaxis 1.747773e-3
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 1.785652e-3
GO:0003272 endocardial cushion formation 1.785652e-3
GO:0007021 tubulin complex assembly 1.785652e-3
GO:0002093 auditory receptor cell morphogenesis 1.806007e-3
GO:0060324 face development 1.829071e-3
GO:0034440 lipid oxidation 1.839111e-3
GO:0021892 cerebral cortex GABAergic interneuron differentiation 1.843228e-3
GO:0050706 regulation of interleukin-1 beta secretion 1.849233e-3
GO:0030237 female sex determination 1.876097e-3
GO:0007499 ectoderm and mesoderm interaction 1.876097e-3
GO:0071379 cellular response to prostaglandin stimulus 1.884715e-3
GO:0010722 regulation of ferrochelatase activity 1.886972e-3
GO:0015734 taurine transport 1.886972e-3
GO:0006848 pyruvate transport 1.886972e-3
GO:0045599 negative regulation of fat cell differentiation 1.887899e-3
GO:0048280 vesicle fusion with Golgi apparatus 1.909409e-3
GO:0071044 histone mRNA catabolic process 1.914263e-3
GO:0002864 regulation of acute inflammatory response to antigenic stimulus 1.922769e-3
GO:0044236 multicellular organismal metabolic process 1.982502e-3
GO:0007346 regulation of mitotic cell cycle 1.988957e-3
GO:0010042 response to manganese ion 1.996661e-3
GO:0070206 protein trimerization 2.059325e-3
GO:0045163 clustering of voltage-gated potassium channels 2.122779e-3
GO:0050704 regulation of interleukin-1 secretion 2.158888e-3
GO:0012501 programmed cell death 2.162106e-3
GO:0061011 hepatic duct development 2.163848e-3
GO:0008334 histone mRNA metabolic process 2.202302e-3
GO:0010043 response to zinc ion 2.215583e-3
GO:0010948 negative regulation of cell cycle process 2.234813e-3
GO:0035625 epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway 2.242800e-3
GO:0000910 cytokinesis 2.263193e-3
GO:0032863 activation of Rac GTPase activity 2.319348e-3
GO:0043029 T cell homeostasis 2.326813e-3
GO:0044259 multicellular organismal macromolecule metabolic process 2.335726e-3
GO:0006915 apoptosis 2.347176e-3
GO:0010763 positive regulation of fibroblast migration 2.357961e-3
GO:0016570 histone modification 2.375844e-3
GO:0032376 positive regulation of cholesterol transport 2.376878e-3
GO:0006518 peptide metabolic process 2.381626e-3
GO:0051534 negative regulation of NFAT protein import into nucleus 2.395305e-3
GO:0060197 cloacal septation 2.411659e-3
GO:0010901 regulation of very-low-density lipoprotein particle remodeling 2.411659e-3
GO:0043588 skin development 2.427346e-3
GO:0035993 deltoid tuberosity development 2.449116e-3
GO:0034341 response to interferon-gamma 2.469370e-3
GO:0015816 glycine transport 2.481306e-3
GO:0051881 regulation of mitochondrial membrane potential 2.493989e-3
GO:0007130 synaptonemal complex assembly 2.498241e-3
GO:0071482 cellular response to light stimulus 2.573008e-3
GO:0002706 regulation of lymphocyte mediated immunity 2.581311e-3
GO:0050765 negative regulation of phagocytosis 2.598806e-3
GO:0014826 vein smooth muscle contraction 2.598806e-3
GO:0060026 convergent extension 2.607515e-3
GO:0010888 negative regulation of lipid storage 2.616608e-3
GO:0000154 rRNA modification 2.662756e-3
GO:0007004 telomere maintenance via telomerase 2.701862e-3
GO:0023056 positive regulation of signaling 2.712935e-3
GO:0071985 multivesicular body sorting pathway 2.750087e-3
GO:0034728 nucleosome organization 2.768391e-3
GO:0030823 regulation of cGMP metabolic process 2.770183e-3
GO:0006479 protein methylation 2.785660e-3
GO:0072144 glomerular mesangial cell development 2.797931e-3
GO:0072011 glomerular endothelium development 2.797931e-3
GO:0060035 notochord cell development 2.797931e-3
GO:0007192 activation of adenylate cyclase activity by serotonin receptor signaling pathway 2.797931e-3
GO:0060325 face morphogenesis 2.826569e-3
GO:0010647 positive regulation of cell communication 2.833092e-3
GO:0060022 hard palate development 2.837610e-3
GO:0014013 regulation of gliogenesis 2.839903e-3
GO:0051568 histone H3-K4 methylation 2.844326e-3
GO:0060253 negative regulation of glial cell proliferation 2.858853e-3
GO:0034969 histone arginine methylation 2.909529e-3
GO:0042347 negative regulation of NF-kappaB import into nucleus 2.914301e-3
GO:0000226 microtubule cytoskeleton organization 2.925936e-3
GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus 2.931904e-3
GO:0023019 signal transduction involved in regulation of gene expression 2.936379e-3
GO:0048850 hypophysis morphogenesis 2.952342e-3
GO:0043217 myelin maintenance 2.960573e-3
GO:0060751 branch elongation involved in mammary gland duct branching 3.030706e-3
GO:0006073 cellular glucan metabolic process 3.070294e-3
GO:0042254 ribosome biogenesis 3.085198e-3
GO:0071356 cellular response to tumor necrosis factor 3.086022e-3
GO:0061325 cell proliferation involved in outflow tract morphogenesis 3.107318e-3
GO:0003253 cardiac neural crest cell migration involved in outflow tract morphogenesis 3.107318e-3
GO:0060127 prolactin secreting cell differentiation 3.107318e-3
GO:0035924 cellular response to vascular endothelial growth factor stimulus 3.160627e-3
GO:0006066 alcohol metabolic process 3.169493e-3
GO:0046112 nucleobase biosynthetic process 3.191481e-3
GO:0010833 telomere maintenance via telomere lengthening 3.206771e-3
GO:0016569 covalent chromatin modification 3.231107e-3
GO:0045604 regulation of epidermal cell differentiation 3.286738e-3
GO:0033026 negative regulation of mast cell apoptosis 3.351137e-3
GO:0072553 terminal button organization 3.379012e-3
GO:0061050 regulation of cell growth involved in cardiac muscle cell development 3.384814e-3
GO:0000093 mitotic telophase 3.392037e-3
GO:0002513 tolerance induction to self antigen 3.423640e-3
GO:0043519 regulation of myosin II filament organization 3.426144e-3
GO:0042440 pigment metabolic process 3.465449e-3
GO:0048319 axial mesoderm morphogenesis 3.514481e-3
GO:0010523 negative regulation of calcium ion transport into cytosol 3.514481e-3
GO:0046110 xanthine metabolic process 3.523191e-3
GO:0048841 regulation of axon extension involved in axon guidance 3.541012e-3
GO:0055025 positive regulation of cardiac muscle tissue development 3.580077e-3
GO:0002418 immune response to tumor cell 3.620354e-3
GO:0019377 glycolipid catabolic process 3.621720e-3
GO:0045839 negative regulation of mitosis 3.635643e-3
GO:0051289 protein homotetramerization 3.662991e-3
GO:0006325 chromatin organization 3.713938e-3
GO:0034694 response to prostaglandin stimulus 3.734729e-3
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation 3.754898e-3
GO:0045911 positive regulation of DNA recombination 3.792391e-3
GO:0006817 phosphate ion transport 3.817025e-3
GO:0060561 apoptosis involved in morphogenesis 3.819760e-3
GO:0046578 regulation of Ras protein signal transduction 3.837782e-3
GO:0032851 positive regulation of Rab GTPase activity 3.843445e-3
GO:0042424 catecholamine catabolic process 3.924947e-3
GO:0030509 BMP signaling pathway 3.967184e-3


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0071870 cellular response to catecholamine stimulus 1.674343e-12
GO:0071874 cellular response to norepinephrine stimulus 2.396422e-11
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB cascade 3.138666e-10
GO:0031055 chromatin remodeling at centromere 1.713197e-8
GO:0060461 right lung morphogenesis 4.053559e-8
GO:0090131 mesenchyme migration 4.053559e-8
GO:0060446 branching involved in open tracheal system development 4.053559e-8
GO:0014822 detection of wounding 4.053559e-8
GO:0048371 lateral mesodermal cell differentiation 4.053559e-8
GO:0048613 embryonic ectodermal digestive tract morphogenesis 4.053559e-8
GO:0048566 embryonic digestive tract development 4.515185e-8
GO:0045814 negative regulation of gene expression, epigenetic 6.403893e-8
GO:0070245 positive regulation of thymocyte apoptosis 8.155481e-8
GO:0007044 cell-substrate junction assembly 8.759291e-8
GO:0070234 positive regulation of T cell apoptosis 1.328265e-7
GO:0009303 rRNA transcription 2.127390e-7
GO:0019060 intracellular transport of viral proteins in host cell 2.223967e-7
GO:0046967 cytosol to ER transport 2.223967e-7
GO:0000238 zygotene 3.999134e-7
GO:0060948 cardiac vascular smooth muscle cell development 5.196099e-7
GO:0003281 ventricular septum development 5.215539e-7
GO:0032606 type I interferon production 5.915518e-7
GO:0070243 regulation of thymocyte apoptosis 6.721793e-7
GO:0046485 ether lipid metabolic process 9.755894e-7
GO:0070232 regulation of T cell apoptosis 1.064831e-6
GO:0033085 negative regulation of T cell differentiation in thymus 1.497503e-6
GO:0002792 negative regulation of peptide secretion 1.510115e-6
GO:0000165 MAPKKK cascade 1.699809e-6
GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway 2.196196e-6
GO:0060458 right lung development 2.465484e-6
GO:0014819 regulation of skeletal muscle contraction 2.906416e-6
GO:0033993 response to lipid 3.220500e-6
GO:0045580 regulation of T cell differentiation 3.504104e-6
GO:0030818 negative regulation of cAMP biosynthetic process 3.573931e-6
GO:0034329 cell junction assembly 3.575322e-6
GO:0048240 sperm capacitation 3.688100e-6
GO:0097107 postsynaptic density assembly 4.862346e-6
GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity 4.862346e-6
GO:0032765 positive regulation of mast cell cytokine production 4.862346e-6
GO:0002431 Fc receptor mediated stimulatory signaling pathway 4.862346e-6
GO:0045060 negative thymic T cell selection 5.389524e-6
GO:0097084 vascular smooth muscle cell development 6.178549e-6
GO:0002649 regulation of tolerance induction to self antigen 6.204285e-6
GO:0033081 regulation of T cell differentiation in thymus 6.441740e-6
GO:0002885 positive regulation of hypersensitivity 6.816704e-6
GO:0034330 cell junction organization 7.201167e-6
GO:0007183 SMAD protein complex assembly 7.647157e-6
GO:2000108 positive regulation of leukocyte apoptosis 8.031377e-6
GO:0031508 centromeric heterochromatin formation 8.308650e-6
GO:0007243 intracellular protein kinase cascade 9.025837e-6
GO:0033026 negative regulation of mast cell apoptosis 9.089057e-6
GO:0002863 positive regulation of inflammatory response to antigenic stimulus 9.588584e-6
GO:0000187 activation of MAPK activity 1.091371e-5
GO:0045351 type I interferon biosynthetic process 1.181233e-5
GO:2000377 regulation of reactive oxygen species metabolic process 1.211363e-5
GO:0045980 negative regulation of nucleotide metabolic process 1.283283e-5
GO:0009988 cell-cell recognition 1.290535e-5
GO:0003279 cardiac septum development 1.344633e-5
GO:0031448 positive regulation of fast-twitch skeletal muscle fiber contraction 1.503477e-5
GO:0006473 protein acetylation 1.806055e-5
GO:2000106 regulation of leukocyte apoptosis 1.991878e-5
GO:0090278 negative regulation of peptide hormone secretion 2.308292e-5
GO:0051043 regulation of membrane protein ectodomain proteolysis 2.536567e-5
GO:0021918 regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment 2.709314e-5
GO:0021905 forebrain-midbrain boundary formation 2.709314e-5
GO:0021902 commitment of neuronal cell to specific neuron type in forebrain 2.709314e-5
GO:0003322 pancreatic A cell development 2.709314e-5
GO:0006342 chromatin silencing 2.817781e-5
GO:0046638 positive regulation of alpha-beta T cell differentiation 3.221586e-5
GO:0060977 coronary vasculature morphogenesis 3.287492e-5
GO:0070230 positive regulation of lymphocyte apoptosis 3.405586e-5
GO:0006970 response to osmotic stress 3.516998e-5
GO:2000653 regulation of genetic imprinting 3.672006e-5
GO:0043252 sodium-independent organic anion transport 3.672006e-5
GO:0045198 establishment of epithelial cell apical/basal polarity 3.838667e-5
GO:0046124 purine deoxyribonucleoside catabolic process 3.857306e-5
GO:0001778 plasma membrane repair 3.864792e-5
GO:0043383 negative T cell selection 4.024714e-5
GO:0048170 positive regulation of long-term neuronal synaptic plasticity 4.107387e-5
GO:0032148 activation of protein kinase B activity 4.153380e-5
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 4.298311e-5
GO:0090042 tubulin deacetylation 4.500819e-5
GO:0070846 Hsp90 deacetylation 4.500819e-5
GO:0019882 antigen processing and presentation 4.581873e-5
GO:0043525 positive regulation of neuron apoptosis 5.031895e-5
GO:0046676 negative regulation of insulin secretion 5.060579e-5
GO:0070301 cellular response to hydrogen peroxide 5.477781e-5
GO:0034508 centromere complex assembly 5.758335e-5
GO:0090316 positive regulation of intracellular protein transport 6.426036e-5
GO:0003289 atrial septum primum morphogenesis 6.471706e-5
GO:0021773 striatal medium spiny neuron differentiation 6.612153e-5
GO:0008631 induction of apoptosis by oxidative stress 6.612153e-5
GO:0048557 embryonic digestive tract morphogenesis 6.671332e-5
GO:0046373 L-arabinose metabolic process 7.784024e-5
GO:0035625 epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway 8.070097e-5
GO:0046637 regulation of alpha-beta T cell differentiation 8.151757e-5
GO:0042307 positive regulation of protein import into nucleus 8.170027e-5
GO:0033025 regulation of mast cell apoptosis 8.925959e-5
GO:0002864 regulation of acute inflammatory response to antigenic stimulus 8.929671e-5
GO:0045627 positive regulation of T-helper 1 cell differentiation 9.245850e-5
GO:0002883 regulation of hypersensitivity 9.703136e-5
GO:0071407 cellular response to organic cyclic compound 9.782421e-5
GO:0042306 regulation of protein import into nucleus 9.942629e-5
GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus 1.006352e-4
GO:0051222 positive regulation of protein transport 1.061832e-4
GO:0045061 thymic T cell selection 1.078652e-4
GO:0006538 glutamate catabolic process 1.135336e-4
GO:0000387 spliceosomal snRNP assembly 1.135408e-4
GO:0021796 cerebral cortex regionalization 1.135408e-4
GO:0007339 binding of sperm to zona pellucida 1.170678e-4
GO:0060412 ventricular septum morphogenesis 1.261903e-4
GO:0060425 lung morphogenesis 1.288887e-4
GO:0046121 deoxyribonucleoside catabolic process 1.343864e-4
GO:0034764 positive regulation of transmembrane transport 1.363478e-4
GO:0002861 regulation of inflammatory response to antigenic stimulus 1.386996e-4
GO:0043305 negative regulation of mast cell degranulation 1.396256e-4
GO:0042401 cellular biogenic amine biosynthetic process 1.437257e-4
GO:0090076 relaxation of skeletal muscle 1.513966e-4
GO:0032470 elevation of endoplasmic reticulum calcium ion concentration 1.513966e-4
GO:0002250 adaptive immune response 1.575178e-4
GO:0045582 positive regulation of T cell differentiation 1.594537e-4
GO:0006346 methylation-dependent chromatin silencing 1.612302e-4
GO:0048041 focal adhesion assembly 1.662524e-4
GO:0003183 mitral valve morphogenesis 1.687366e-4
GO:0043543 protein acylation 1.700665e-4
GO:0071882 activation of phospholipase C activity by adrenergic receptor signaling pathway 1.703301e-4
GO:0071881 inhibition of adenylate cyclase activity by adrenergic receptor signaling pathway 1.703301e-4
GO:0050857 positive regulation of antigen receptor-mediated signaling pathway 1.722767e-4
GO:0040029 regulation of gene expression, epigenetic 1.761840e-4
GO:0051044 positive regulation of membrane protein ectodomain proteolysis 1.786003e-4
GO:0002673 regulation of acute inflammatory response 1.789815e-4
GO:0006930 substrate-dependent cell migration, cell extension 1.824943e-4
GO:0045065 cytotoxic T cell differentiation 1.832404e-4
GO:0006475 internal protein amino acid acetylation 1.836949e-4
GO:0046165 alcohol biosynthetic process 1.849725e-4
GO:0046173 polyol biosynthetic process 1.931099e-4
GO:0033617 mitochondrial respiratory chain complex IV assembly 2.014318e-4
GO:0007224 smoothened signaling pathway 2.073311e-4
GO:0045619 regulation of lymphocyte differentiation 2.117773e-4
GO:0051659 maintenance of mitochondrion location 2.121358e-4
GO:0045358 negative regulation of interferon-beta biosynthetic process 2.168786e-4
GO:0021539 subthalamus development 2.234190e-4
GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process 2.234190e-4
GO:0071418 cellular response to amine stimulus 2.239820e-4
GO:0014009 glial cell proliferation 2.293569e-4
GO:0006044 N-acetylglucosamine metabolic process 2.293569e-4
GO:0006540 glutamate decarboxylation to succinate 2.420344e-4
GO:0060563 neuroepithelial cell differentiation 2.665205e-4
GO:0034502 protein localization to chromosome 2.683848e-4
GO:0042089 cytokine biosynthetic process 2.720443e-4
GO:0021877 forebrain neuron fate commitment 2.843969e-4
GO:0033157 regulation of intracellular protein transport 2.932413e-4
GO:0060463 lung lobe morphogenesis 2.942521e-4
GO:0090035 positive regulation of cellular chaperone-mediated protein complex assembly 2.986606e-4
GO:0050689 negative regulation of defense response to virus by host 2.986606e-4
GO:0018158 protein oxidation 2.986606e-4
GO:0002891 positive regulation of immunoglobulin mediated immune response 3.025459e-4
GO:2000677 regulation of transcription regulatory region DNA binding 3.036878e-4
GO:0071417 cellular response to organic nitrogen 3.050997e-4
GO:0045058 T cell selection 3.054793e-4
GO:2000379 positive regulation of reactive oxygen species metabolic process 3.061743e-4
GO:0000460 maturation of 5.8S rRNA 3.080829e-4
GO:0045581 negative regulation of T cell differentiation 3.128827e-4
GO:0046635 positive regulation of alpha-beta T cell activation 3.146572e-4
GO:0051956 negative regulation of amino acid transport 3.241945e-4
GO:0002922 positive regulation of humoral immune response 3.318224e-4
GO:0001709 cell fate determination 3.483536e-4
GO:0021798 forebrain dorsal/ventral pattern formation 3.489286e-4
GO:0050854 regulation of antigen receptor-mediated signaling pathway 3.497896e-4
GO:0007288 sperm axoneme assembly 3.644494e-4
GO:0060161 positive regulation of dopamine receptor signaling pathway 3.750796e-4
GO:0009817 defense response to fungus, incompatible interaction 3.821769e-4
GO:0071316 cellular response to nicotine 3.852026e-4
GO:0071385 cellular response to glucocorticoid stimulus 3.875213e-4
GO:0007406 negative regulation of neuroblast proliferation 3.929334e-4
GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation 4.031115e-4
GO:0042421 norepinephrine biosynthetic process 4.031115e-4
GO:0006378 mRNA polyadenylation 4.046662e-4
GO:0018206 peptidyl-methionine modification 4.204434e-4
GO:0018394 peptidyl-lysine acetylation 4.610248e-4
GO:0051054 positive regulation of DNA metabolic process 4.676872e-4
GO:0032846 positive regulation of homeostatic process 4.716473e-4
GO:0060022 hard palate development 5.064240e-4
GO:0072404 signal transduction involved in G1/S transition checkpoint 5.078487e-4
GO:0034616 response to laminar fluid shear stress 5.078487e-4
GO:0051101 regulation of DNA binding 5.113318e-4
GO:0034614 cellular response to reactive oxygen species 5.126985e-4
GO:0002675 positive regulation of acute inflammatory response 5.139955e-4
GO:0008625 induction of apoptosis via death domain receptors 5.216402e-4
GO:0032740 positive regulation of interleukin-17 production 5.376439e-4
GO:0032388 positive regulation of intracellular transport 5.497582e-4
GO:0035036 sperm-egg recognition 5.503174e-4
GO:0040034 regulation of development, heterochronic 5.644324e-4
GO:0060979 vasculogenesis involved in coronary vascular morphogenesis 5.680311e-4
GO:0071222 cellular response to lipopolysaccharide 6.170020e-4
GO:0007254 JNK cascade 6.286995e-4
GO:0072395 signal transduction involved in cell cycle checkpoint 6.295672e-4
GO:0045740 positive regulation of DNA replication 6.314248e-4
GO:0033077 T cell differentiation in thymus 6.346873e-4
GO:0003211 cardiac ventricle formation 6.395392e-4
GO:0000281 cytokinesis after mitosis 6.427828e-4
GO:0034509 centromeric core chromatin assembly 6.519733e-4
GO:0034080 CenH3-containing nucleosome assembly at centromere 6.519733e-4
GO:0031129 inductive cell-cell signaling 6.519733e-4
GO:0001812 positive regulation of type I hypersensitivity 6.520317e-4
GO:0007286 spermatid development 6.543803e-4
GO:0006568 tryptophan metabolic process 6.566946e-4
GO:0018393 internal peptidyl-lysine acetylation 6.627981e-4
GO:2000779 regulation of double-strand break repair 6.635670e-4
GO:0001738 morphogenesis of a polarized epithelium 6.645067e-4
GO:0033160 positive regulation of protein import into nucleus, translocation 6.673805e-4
GO:0016573 histone acetylation 6.687101e-4
GO:0008643 carbohydrate transport 6.787839e-4
GO:0003215 cardiac right ventricle morphogenesis 6.800942e-4
GO:0097022 lymphocyte migration into lymph node 7.094565e-4
GO:0072610 interleukin-12 secretion 7.094565e-4
GO:0045596 negative regulation of cell differentiation 7.179547e-4
GO:0030217 T cell differentiation 7.203748e-4
GO:0048535 lymph node development 7.265590e-4
GO:0033205 cell cycle cytokinesis 7.291102e-4
GO:0060407 negative regulation of penile erection 7.324898e-4
GO:0060169 negative regulation of adenosine receptor signaling pathway 7.324898e-4
GO:2000256 positive regulation of male germ cell proliferation 7.324898e-4
GO:0046111 xanthine biosynthetic process 7.324898e-4
GO:0072355 histone H3-T3 phosphorylation 7.324898e-4
GO:0015739 sialic acid transport 7.324898e-4
GO:0002314 germinal center B cell differentiation 7.324898e-4
GO:0006157 deoxyadenosine catabolic process 7.324898e-4
GO:0009637 response to blue light 7.324898e-4
GO:0042231 interleukin-13 biosynthetic process 7.324898e-4
GO:0046061 dATP catabolic process 7.324898e-4
GO:0090086 negative regulation of protein deubiquitination 7.426680e-4
GO:0046888 negative regulation of hormone secretion 7.503156e-4
GO:0044283 small molecule biosynthetic process 7.535892e-4
GO:2000172 regulation of branching morphogenesis of a nerve 7.721949e-4
GO:0019441 tryptophan catabolic process to kynurenine 7.725829e-4
GO:0060411 cardiac septum morphogenesis 8.183919e-4
GO:0048505 regulation of timing of cell differentiation 8.350406e-4
GO:0042761 very long-chain fatty acid biosynthetic process 8.422990e-4
GO:0048515 spermatid differentiation 8.472294e-4
GO:0070542 response to fatty acid 8.625528e-4
GO:0033037 polysaccharide localization 8.637606e-4
GO:0048002 antigen processing and presentation of peptide antigen 8.797899e-4
GO:0002518 lymphocyte chemotaxis across high endothelial venule 8.821966e-4
GO:0003207 cardiac chamber formation 8.850036e-4
GO:0050428 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process 9.142626e-4
GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification 9.237946e-4
GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 9.266302e-4
GO:0021983 pituitary gland development 9.276502e-4
GO:0032760 positive regulation of tumor necrosis factor production 9.407132e-4
GO:0043304 regulation of mast cell degranulation 9.575863e-4
GO:0070228 regulation of lymphocyte apoptosis 1.002533e-3
GO:0033132 negative regulation of glucokinase activity 1.010893e-3
GO:0048568 embryonic organ development 1.010913e-3
GO:0051657 maintenance of organelle location 1.015393e-3
GO:2000822 regulation of behavioral fear response 1.019130e-3
GO:2000429 negative regulation of neutrophil aggregation 1.024991e-3
GO:0071638 negative regulation of monocyte chemotactic protein-1 production 1.024991e-3
GO:2000469 negative regulation of peroxidase activity 1.024991e-3
GO:0000027 ribosomal large subunit assembly 1.024991e-3
GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase 1.024991e-3
GO:0035726 common myeloid progenitor cell proliferation 1.024991e-3
GO:0018205 peptidyl-lysine modification 1.069688e-3
GO:0045006 DNA deamination 1.070862e-3
GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification 1.070862e-3
GO:0051052 regulation of DNA metabolic process 1.074163e-3
GO:0017004 cytochrome complex assembly 1.099198e-3
GO:0019049 evasion of host defenses by virus 1.099198e-3
GO:0080164 regulation of nitric oxide metabolic process 1.104933e-3
GO:0060112 generation of ovulation cycle rhythm 1.104933e-3
GO:0001988 positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure 1.104933e-3
GO:0031347 regulation of defense response 1.109710e-3
GO:0042107 cytokine metabolic process 1.115318e-3
GO:0042538 hyperosmotic salinity response 1.126989e-3
GO:0090322 regulation of superoxide metabolic process 1.133718e-3
GO:0072091 regulation of stem cell proliferation 1.135885e-3
GO:0097026 dendritic cell dendrite assembly 1.136594e-3
GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 1.136594e-3
GO:0006275 regulation of DNA replication 1.155035e-3
GO:0043434 response to peptide hormone stimulus 1.172364e-3
GO:0003357 noradrenergic neuron differentiation 1.220941e-3
GO:0071479 cellular response to ionizing radiation 1.230188e-3
GO:0006351 transcription, DNA-dependent 1.230317e-3
GO:0071779 G1/S transition checkpoint 1.240361e-3
GO:0034105 positive regulation of tissue remodeling 1.240361e-3
GO:0072539 T-helper 17 cell differentiation 1.243302e-3
GO:0045994 positive regulation of translational initiation by iron 1.243302e-3
GO:0061048 negative regulation of branching involved in lung morphogenesis 1.243302e-3
GO:0002037 negative regulation of L-glutamate transport 1.243302e-3
GO:0018199 peptidyl-glutamine modification 1.243302e-3
GO:0034116 positive regulation of heterotypic cell-cell adhesion 1.243302e-3
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 1.277945e-3
GO:0032774 RNA biosynthetic process 1.290561e-3
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1.293827e-3
GO:0002003 angiotensin maturation 1.304310e-3
GO:2000648 positive regulation of stem cell proliferation 1.331177e-3
GO:0006955 immune response 1.338351e-3
GO:0042110 T cell activation 1.339017e-3
GO:0046634 regulation of alpha-beta T cell activation 1.372859e-3
GO:0048562 embryonic organ morphogenesis 1.385594e-3
GO:0046649 lymphocyte activation 1.397110e-3
GO:0002376 immune system process 1.397648e-3
GO:0006952 defense response 1.450471e-3
GO:0003348 cardiac endothelial cell differentiation 1.461635e-3
GO:0006633 fatty acid biosynthetic process 1.487369e-3
GO:0050995 negative regulation of lipid catabolic process 1.496530e-3
GO:0031444 slow-twitch skeletal muscle fiber contraction 1.557580e-3
GO:0002175 protein localization to paranode region of axon 1.557580e-3
GO:0045647 negative regulation of erythrocyte differentiation 1.557740e-3
GO:0032471 reduction of endoplasmic reticulum calcium ion concentration 1.563401e-3
GO:0060976 coronary vasculature development 1.573801e-3
GO:0045780 positive regulation of bone resorption 1.591822e-3
GO:0030308 negative regulation of cell growth 1.612529e-3
GO:0060413 atrial septum morphogenesis 1.646630e-3
GO:0071356 cellular response to tumor necrosis factor 1.672980e-3
GO:0045321 leukocyte activation 1.694386e-3
GO:0001819 positive regulation of cytokine production 1.708645e-3
GO:0032288 myelin assembly 1.734665e-3
GO:0007184 SMAD protein import into nucleus 1.734665e-3
GO:2000381 negative regulation of mesoderm development 1.754554e-3
GO:0010991 negative regulation of SMAD protein complex assembly 1.754554e-3
GO:0043932 ossification involved in bone remodeling 1.754554e-3
GO:0048714 positive regulation of oligodendrocyte differentiation 1.769526e-3
GO:0006283 transcription-coupled nucleotide-excision repair 1.780603e-3
GO:0048333 mesodermal cell differentiation 1.807446e-3
GO:0031365 N-terminal protein amino acid modification 1.814475e-3
GO:0042255 ribosome assembly 1.841197e-3
GO:0032731 positive regulation of interleukin-1 beta production 1.845034e-3
GO:0045741 positive regulation of epidermal growth factor-activated receptor activity 1.854758e-3
GO:0021978 telencephalon regionalization 1.854758e-3
GO:0000059 protein import into nucleus, docking 1.856809e-3
GO:0051823 regulation of synapse structural plasticity 1.862881e-3
GO:0071803 positive regulation of podosome assembly 1.866148e-3
GO:0035886 vascular smooth muscle cell differentiation 1.881073e-3
GO:0043392 negative regulation of DNA binding 1.890663e-3
GO:0071359 cellular response to dsRNA 1.909056e-3
GO:0009262 deoxyribonucleotide metabolic process 1.918582e-3
GO:0043406 positive regulation of MAP kinase activity 1.927415e-3
GO:0034260 negative regulation of GTPase activity 1.928894e-3
GO:0009719 response to endogenous stimulus 1.930673e-3
GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process 1.931629e-3
GO:0031018 endocrine pancreas development 1.939571e-3
GO:0032844 regulation of homeostatic process 1.951685e-3
GO:0006114 glycerol biosynthetic process 1.965544e-3
GO:0010741 negative regulation of intracellular protein kinase cascade 1.996084e-3
GO:0003170 heart valve development 2.010005e-3
GO:0031324 negative regulation of cellular metabolic process 2.014121e-3
GO:0071219 cellular response to molecule of bacterial origin 2.077565e-3
GO:0090200 positive regulation of release of cytochrome c from mitochondria 2.078374e-3
GO:0009651 response to salt stress 2.104973e-3
GO:0050862 positive regulation of T cell receptor signaling pathway 2.113272e-3
GO:0090181 regulation of cholesterol metabolic process 2.118563e-3
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 2.136951e-3
GO:0007352 zygotic specification of dorsal/ventral axis 2.164457e-3
GO:0090023 positive regulation of neutrophil chemotaxis 2.173959e-3
GO:0031098 stress-activated protein kinase signaling cascade 2.175305e-3
GO:0045620 negative regulation of lymphocyte differentiation 2.189169e-3
GO:0060557 positive regulation of vitamin D biosynthetic process 2.221441e-3
GO:0003290 atrial septum secundum morphogenesis 2.221441e-3
GO:0002651 positive regulation of tolerance induction to self antigen 2.221441e-3
GO:0001798 positive regulation of type IIa hypersensitivity 2.240318e-3
GO:2000758 positive regulation of peptidyl-lysine acetylation 2.291938e-3
GO:0070845 polyubiquitinated misfolded protein transport 2.301680e-3
GO:0009181 purine ribonucleoside diphosphate catabolic process 2.308073e-3
GO:0070265 necrotic cell death 2.308073e-3
GO:0009120 deoxyribonucleoside metabolic process 2.308073e-3
GO:0003195 tricuspid valve formation 2.308073e-3
GO:0030497 fatty acid elongation 2.330872e-3
GO:2000679 positive regulation of transcription regulatory region DNA binding 2.348813e-3
GO:0046822 regulation of nucleocytoplasmic transport 2.365769e-3
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 2.374896e-3
GO:0015870 acetylcholine transport 2.410859e-3
GO:0006950 response to stress 2.435792e-3
GO:0035640 exploration behavior 2.575841e-3
GO:0071216 cellular response to biotic stimulus 2.580599e-3
GO:0006515 misfolded or incompletely synthesized protein catabolic process 2.606538e-3
GO:0001805 positive regulation of type III hypersensitivity 2.623349e-3
GO:0021879 forebrain neuron differentiation 2.634820e-3
GO:0060426 lung vasculature development 2.704671e-3
GO:0071549 cellular response to dexamethasone stimulus 2.740745e-3
GO:0006094 gluconeogenesis 2.744931e-3
GO:0034261 negative regulation of Ras GTPase activity 2.755211e-3
GO:0006927 transformed cell apoptosis 2.755211e-3
GO:0006105 succinate metabolic process 2.770577e-3
GO:0042254 ribosome biogenesis 2.819338e-3
GO:0032008 positive regulation of TOR signaling cascade 2.884895e-3
GO:0034625 fatty acid elongation, monounsaturated fatty acid 2.892925e-3
GO:0009892 negative regulation of metabolic process 2.897448e-3
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 2.931423e-3
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation 2.953969e-3
GO:0043654 recognition of apoptotic cell 2.969341e-3
GO:0045861 negative regulation of proteolysis 2.977148e-3
GO:0000060 protein import into nucleus, translocation 2.977529e-3
GO:0019368 fatty acid elongation, unsaturated fatty acid 2.998604e-3
GO:0032383 regulation of intracellular cholesterol transport 3.045271e-3
GO:0010826 negative regulation of centrosome duplication 3.045271e-3
GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus 3.052774e-3
GO:0001555 oocyte growth 3.052774e-3
GO:0060947 cardiac vascular smooth muscle cell differentiation 3.055935e-3
GO:0043631 RNA polyadenylation 3.070116e-3
GO:0071346 cellular response to interferon-gamma 3.080861e-3
GO:0009890 negative regulation of biosynthetic process 3.085213e-3
GO:0003231 cardiac ventricle development 3.087843e-3
GO:0010758 regulation of macrophage chemotaxis 3.096068e-3
GO:2000412 positive regulation of thymocyte migration 3.166789e-3
GO:0002449 lymphocyte mediated immunity 3.222340e-3
GO:0007256 activation of JNKK activity 3.323284e-3
GO:0001775 cell activation 3.354534e-3
GO:0045624 positive regulation of T-helper cell differentiation 3.399173e-3
GO:0007141 male meiosis I 3.420371e-3
GO:0002606 positive regulation of dendritic cell antigen processing and presentation 3.420371e-3
GO:0032732 positive regulation of interleukin-1 production 3.488353e-3
GO:2000173 negative regulation of branching morphogenesis of a nerve 3.489136e-3
GO:0070935 3'-UTR-mediated mRNA stabilization 3.489136e-3
GO:0060547 negative regulation of necrotic cell death 3.551089e-3
GO:0071218 cellular response to misfolded protein 3.614047e-3
GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development 3.614047e-3
GO:0032916 positive regulation of transforming growth factor beta3 production 3.614047e-3
GO:0043011 myeloid dendritic cell differentiation 3.630440e-3
GO:0045621 positive regulation of lymphocyte differentiation 3.639505e-3
GO:0048368 lateral mesoderm development 3.641191e-3
GO:0048617 embryonic foregut morphogenesis 3.679138e-3
GO:0051856 adhesion to symbiont 3.684946e-3
GO:0003283 atrial septum development 3.689524e-3
GO:0003205 cardiac chamber development 3.765873e-3
GO:0003179 heart valve morphogenesis 3.784506e-3
GO:2000384 negative regulation of ectoderm development 3.801437e-3
GO:0032386 regulation of intracellular transport 3.803688e-3
GO:0033209 tumor necrosis factor-mediated signaling pathway 3.822071e-3
GO:0033059 cellular pigmentation 3.832714e-3
GO:0060695 negative regulation of cholesterol transporter activity 3.871287e-3
GO:0046102 inosine metabolic process 3.871287e-3
GO:0009217 purine deoxyribonucleoside triphosphate catabolic process 3.871287e-3
GO:0015759 beta-glucoside transport 3.871287e-3
GO:0070267 oncosis 3.925378e-3
GO:0019255 glucose 1-phosphate metabolic process 3.964491e-3
GO:0010457 centriole-centriole cohesion 3.964491e-3
GO:0016070 RNA metabolic process 3.992664e-3
GO:0007173 epidermal growth factor receptor signaling pathway 4.031124e-3
GO:0045089 positive regulation of innate immune response 4.041069e-3
GO:0031349 positive regulation of defense response 4.053139e-3
GO:0046333 octopamine metabolic process 4.085898e-3
GO:0051142 positive regulation of NK T cell proliferation 4.085898e-3
GO:0042309 homoiothermy 4.085898e-3
GO:0032863 activation of Rac GTPase activity 4.104141e-3
GO:0048484 enteric nervous system development 4.184539e-3
GO:0014823 response to activity 4.185051e-3
GO:0006476 protein deacetylation 4.201580e-3
GO:0045908 negative regulation of vasodilation 4.226331e-3
GO:0045989 positive regulation of striated muscle contraction 4.229384e-3
GO:0035910 ascending aorta morphogenesis 4.229686e-3
GO:2000761 positive regulation of N-terminal peptidyl-lysine acetylation 4.229686e-3
GO:0006359 regulation of transcription from RNA polymerase III promoter 4.229686e-3
GO:0006958 complement activation, classical pathway 4.234093e-3
GO:0042345 regulation of NF-kappaB import into nucleus 4.246459e-3
GO:0006366 transcription from RNA polymerase II promoter 4.270504e-3
GO:0002763 positive regulation of myeloid leukocyte differentiation 4.272708e-3
GO:0002791 regulation of peptide secretion 4.313110e-3
GO:0045080 positive regulation of chemokine biosynthetic process 4.354212e-3
GO:0051835 positive regulation of synapse structural plasticity 4.412239e-3
GO:0002683 negative regulation of immune system process 4.433545e-3
GO:0002920 regulation of humoral immune response 4.506940e-3
GO:0035089 establishment of apical/basal cell polarity 4.523061e-3
GO:0009186 deoxyribonucleoside diphosphate metabolic process 4.523061e-3
GO:0001771 immunological synapse formation 4.523061e-3
GO:0090074 negative regulation of protein homodimerization activity 4.526758e-3
GO:0006419 alanyl-tRNA aminoacylation 4.526758e-3
GO:0046823 negative regulation of nucleocytoplasmic transport 4.543533e-3
GO:0031663 lipopolysaccharide-mediated signaling pathway 4.569258e-3
GO:0006586 indolalkylamine metabolic process 4.569258e-3
GO:0010569 regulation of double-strand break repair via homologous recombination 4.588147e-3
GO:0043331 response to dsRNA 4.672948e-3
GO:0032808 lacrimal gland development 4.720146e-3
GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus 4.887098e-3
GO:0044403 symbiosis, encompassing mutualism through parasitism 4.929592e-3
GO:0050714 positive regulation of protein secretion 4.973205e-3
GO:0035601 protein deacylation 4.986202e-3
GO:0033006 regulation of mast cell activation involved in immune response 5.012371e-3
GO:0002455 humoral immune response mediated by circulating immunoglobulin 5.017139e-3
GO:0006646 phosphatidylethanolamine biosynthetic process 5.070984e-3
GO:0045625 regulation of T-helper 1 cell differentiation 5.070984e-3
GO:0009950 dorsal/ventral axis specification 5.123599e-3
GO:0050868 negative regulation of T cell activation 5.153732e-3
GO:0006576 cellular biogenic amine metabolic process 5.160706e-3
GO:0021536 diencephalon development 5.194502e-3
GO:0034405 response to fluid shear stress 5.197658e-3
GO:0034626 fatty acid elongation, polyunsaturated fatty acid 5.233604e-3
GO:0031394 positive regulation of prostaglandin biosynthetic process 5.238425e-3
GO:0090130 tissue migration 5.323314e-3
GO:0046168 glycerol-3-phosphate catabolic process 5.326636e-3
GO:0043103 hypoxanthine salvage 5.326636e-3
GO:0032261 purine nucleotide salvage 5.326636e-3
GO:0060997 dendritic spine morphogenesis 5.350688e-3
GO:0031581 hemidesmosome assembly 5.367930e-3
GO:0042271 susceptibility to natural killer cell mediated cytotoxicity 5.382580e-3
GO:0006040 amino sugar metabolic process 5.460873e-3
GO:0070509 calcium ion import 5.584498e-3
GO:0003214 cardiac left ventricle morphogenesis 5.605436e-3
GO:0070293 renal absorption 5.619082e-3
GO:0030913 paranodal junction assembly 5.619082e-3